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At least 595 records · Page 33
All sourcesNASA NTRSDOE OSTI
DOE OSTI2024

Key Takeaways: Second Cohort of Action Plans for Rapid Power Sector Decarbonization

A collaborative report from the Clean Energy Ministerial (CEM), Lessons Learned for Rapid Decarbonization of Power Sectors, was delivered to energy ministers and presented at the 13th CEM (CEM13) in the United States in September 2022. As a result, Action Plans for power sector decarbonization were developed by the first cohort of countries. The fist cohort included India, Australia, Chile, the European Union, and the United Kingdom. The first cohort's Action Plans were presented at CEM14 in India in July 2023. These Action Plans, supported by the 21st Century Power Partnership and other CEM workstreams via direct technical assistance and capacity building, are intended to focus on select implementation actions given each country's existing power sector goals and activities, and are an opportunity for countries to display leadership in power sector decarbonization. The second set of Action Plans has been developed by Brazil, Canada, the United States, and Uruguay, released at CEM15 in Brazil in October 2024.

21st Century Power Partnership↗
DOE OSTI2026

Aeromonas in South Asia: genomic insights into an environmental pathogen and reservoir of antimicrobial resistance

Aeromonads are an ecologically versatile group of bacteria that cause infections in aquatic animals and are recognised as emerging human pathogens. Despite this, our understanding of Aeromonas diversity, especially the relationship between clinical and environmental strains, remains limited. Here, we present a genomic analysis of the Aeromonas genus, comprising 1853 genomes, and a detailed comparison of clinical and environmental strains from South Asia, including 996 newly sequenced genomes from Bangladesh and India. Phylogenetic analyses revealed that Aeromonas is a highly diverse genus, with no distinct clade separating clinical and environmental isolates. We identified 28 Aeromonas species and 905 novel sequence types, comprising 72.5% of the genomes. Notably, we show a high incidence of antimicrobial resistance (AMR) genes across all isolates, including against front and last-line antibiotics. Finally, we highlight frequent misidentification of Aeromonas as Vibrio cholerae, which is relevant to cholera-endemic regions where both genera co-exist and are associated with diarrhoeal disease. Our study underscores Aeromonas as an important environmental AMR reservoir and emerging multi-species pathogen capable of spilling over into human populations.

59 BASIC BIOLOGICAL SCIENCES↗
DOE OSTI2019

Xenicanes attenuate pro-inflammatory 5-lipoxygenase: Prospective natural anti-inflammatory leads from intertidal brown seaweed Padina tetrastromatica

Two previously unreported xenicane class of novaxenicin-type xenicin diterpenoids (1–2) bearing cyclonona[d]furo [2,3-b]pyrandiol and three xeniolide-type diterpenoids with unprecedented octahydrocyclonona[c]pyran-3(1H)-one backbones (3–5) were separated from the organic extract of the intertidal seaweed Padina tetrastomatica (family Dictyotaceae), collected from southern India. The compounds were deduced to bear a xenicane moiety with a 2-oxabicyclo[7.4.0]tridecane cyclic system. The structures of these specialized metabolites were attributed based on the extensive nuclear magnetic resonance spectral analyses, and comparison of related compounds. Xeniolide-type diterpenes (3–5) registered significantly greater attenuation potential against pro-inflammatory 5-lipoxygenase (IC{sub 50} ~ 2.04 mM) than that exhibited by non-steroidal anti-inflammatory drug ibuprofen (IC{sub 50} 4.50 mM, P< 0.05). The xeniolide derivative octahydro-1,7-dihydroxy-4-(4{sup 1}-hydroxy-4{sup 2}-methylpropyl)-6-(6{sup 1}-hydroxy-6{sup 2}-propenyl)-10-methyl-cyclonona[c]pyran-3(1H)-one (5) exhibited comparable antioxidant activity (DPPH IC{sub 50} 1.73 mM) along with standard antioxidative agent α-tocopherol (IC{sub 50} < 2 mM). In silico molecular modelling studies were performed to designate the 5-lipoxygenase inhibitory mechanism of the xenicanes, and the comparison of docking parameters suggested that the xeniolide derivative 5 exhibited least binding energy of −11.56 kcal mol{sup −1}, and that was corroborated with its greater inhibition potential against the pro-inflammatory enzyme. These results demonstrated that the xeniolide-type diterpenoids with previously unreported δ-lactone cyclononane framework might constitute promising anti-inflammatory leads with pro-inflammatory 5-lipoxygenase enzyme inhibitory activities.

60 APPLIED LIFE SCIENCES↗
DOE OSTI2019

Metallothionein Induced Time Dependent Histomorphometric Analysis of Clarias gariepinus Exposed to Cadmium

Cadmium (Cd), an extremely toxic heavy metal is extensively used in modern era because of its constructive chemical and physical properties. Recently Cd contamination was estimated in India’s major cities fresh water ecosystem, which may have firm impact on human health. Hence, this study was aimed to detect the time dependent effect of cadmium in fresh water fish C. gariepinus, a bioindicator species of water pollution. In a controlled environment, fishes were exposed to cadmium for different duration and analyzed for Cd accumulation. Cd induced toxicity was assessed by estimating metallothionein biomarker protein of heavy metal toxicity and histomorphometric changes in liver and kidney. Our results revealed that fish exposed to Cd induced apoptosis in fish tissues via induction of caspases and in contrast the metallothionein was also increased consistently with different doses of Cd exposure. Hence we conclude Cd induced structural damages to fishes are attributed to induction of caspases and estimating MT level in tissues can be effective biomarker to analyze the effect of acute environmental exposure to Cd.

54 ENVIRONMENTAL SCIENCES↗
DOE OSTI2018

Hydrological processes in glacierized high-altitude basins of the western Himalayas

Western Himalaya is a strategically important region, where the water resources are shared by China, India and Pakistan. The economy of the region is largely dependent on the water resources delivered by snow and glacier melt. The presented study used stable isotopes of water to further understand the basin-scale hydro-meteorological, hydrological and recharge processes in three high-altitude mountainous basins of the western Himalayas. The study provided new insights in understanding the dominant factors affecting the isotopic composition of the precipitation, snowpack, glacier melt, streams and springs. It was observed that elevation-dependent post-depositional processes and snowpack evolution resulted in the higher isotopic altitude gradient in snowpacks. The similar temporal trends of isotopic signals in rivers and karst springs reflect the rapid flow transfer due to karstification of the carbonate aquifers. The attenuation of the extreme isotopic input signal in karst springs appears to be due to the mixing of source waters with the underground karst reservoirs. Basin-wise, the input–output response demonstrates the vital role of winter precipitation in maintaining the perennial flow in streams and karst springs in the region. Isotopic data were also used to estimate the mean recharge altitude of the springs.

58 GEOSCIENCES↗
DOE OSTI2019

Factors that impact the outcomes in testicular germ cell tumors in low–middle-income countries

Germ cell tumors (GCTs) are one of the most common tumors in adolescents and young adults. There is paucity of data on GCT from low–middle-income countries (LMIC). The present study was conducted to assess the demographic features, clinical manifestations, pathology, and outcomes of GCT patients treated at our center. Patients with testicular GCT above the age of 18 years, treated at our center from 2001 to 2015 were included in the study. Data were extracted retrospectively from the case records. Event-free survival (EFS) and overall survival (OS) were calculated using the Kaplan–Meier method and the variables were compared using the log-rank test. The study included 421 patients among whom 128 (30%) had a histological diagnosis of seminoma and 293 (70%) had non-seminomatous germ cell tumor (NSGCT). Metastatic disease at presentation was observed in 83/128 (65%) with seminoma and 254/293 (87%) with NSGCT. According to the International Germ Cell Cancer Collaborative Group (IGCCCG) risk stratification for metastatic disease, good- and intermediate-risk seminoma were observed in 55/83 (66%) and 28/83 (34%) patients, respectively, and good-, intermediate-, and poor-risk NSGCT were observed in 82/254 (32%), 76/254 (30%), and 96/254 (38%) patients, respectively. The median follow-up was 32.3 months (range 0.03–200 months). The 3-year OS for the entire cohort was 80.3%. The 3-year OS for seminoma was 91.4%, and for NSGCT was 75.3%. Factors significantly associated with inferior EFS and OS on multivariate analysis included poor performance status, scrotal orchidectomy, carboplatin-based regimen, NSGCT histology, and treatment default. Patients with testicular GCT in India present in an advanced stage and higher IGCCCG risk compared to Western data. Factors unique to LMIC like treatment default, bulky disease, dose compromise, and scrotal orchidectomy have a negative impact on the outcome.

62 RADIOLOGY AND NUCLEAR MEDICINE↗
DOE OSTI2017

Recent aspects of uranium toxicology in medical geology

Uranium (U) is a chemo-toxic, radiotoxic and even a carcinogenic element. Due to its radioactivity, the effects of U on humans health have been extensively investigated. Prolonged U exposure may cause kidney disease and cancer. The geological distribution of U radionuclides is still a great concern for human health. Uranium in groundwater, frequently used as drinking water, and general environmental pollution with U raise concerns about the potential public health problem in several areas of Asia. The particular paleo-geological hallmark of India and other Southern Asiatic regions enhances the risk of U pollution in rural and urban communities. This paper highlights different health and environmental aspects of U as well as uptake and intake. It discusses levels of U in soil and water and the related health issues. Also described are different issues of U pollution, such as U and fertilizers, occupational exposure in miners, use and hazards of U in weapons (depleted U), U and plutonium as catalysts in the reaction between DNA and H{sub 2}O{sub 2,} and recycling of U from groundwater to surface soils in irrigation. For use in medical geology and U research, large databases and data warehouses are currently available in Europe and the United States. - Highlights: • Uranium (U) is a chemo-toxic, radiotoxic and even a carcinogenic element. • Effects of U on humans health have been extensively studied in recent years. • Prolonged U exposure may cause kidney disease and cancer. • Drinking water is a source of U exposure in some parts of the world.

54 ENVIRONMENTAL SCIENCES↗
DOE OSTI2011

Quantification of greenhouse gas emissions from waste management processes for municipalities - A comparative review focusing on Africa

The amount of greenhouse gases (GHG) emitted due to waste management in the cities of developing countries is predicted to rise considerably in the near future; however, these countries have a series of problems in accounting and reporting these gases. Some of these problems are related to the status quo of waste management in the developing world and some to the lack of a coherent framework for accounting and reporting of greenhouse gases from waste at municipal level. This review summarizes and compares GHG emissions from individual waste management processes which make up a municipal waste management system, with an emphasis on developing countries and, in particular, Africa. It should be seen as a first step towards developing a more holistic GHG accounting model for municipalities. The comparison between these emissions from developed and developing countries at process level, reveals that there is agreement on the magnitude of the emissions expected from each process (generation of waste, collection and transport, disposal and recycling). The highest GHG savings are achieved through recycling, and these savings would be even higher in developing countries which rely on coal for energy production (e.g. South Africa, India and China) and where non-motorized collection and transport is used. The highest emissions are due to the methane released by dumpsites and landfills, and these emissions are predicted to increase significantly, unless more of the methane is captured and either flared or used for energy generation. The clean development mechanism (CDM) projects implemented in the developing world have made some progress in this field; however, African countries lag behind.

09 BIOMASS FUELS↗
DOE OSTI2010

Global effects on Ionospheric Weather over the Indian subcontinent at Sunrise and Sunset

Study of Very Low Frequency (VLF) electromagnetic wave is very important for knowing the behavior of the Ionospheric layers due to Sunrise-Sunset, Earthquakes, Solar flares, Solar eclipses and other terrestrial and extra terrestrial radiations. We study the properties of the variation of the VLF signal strength theoretically all over Indian sub-continent. As an example, we concentrate on the VLF signal transmitted by Indian Naval Transmitter VTX at Vijayanarayanam (Latitude 08 deg. 23', Longitude 77 deg. 45') near the southern tip of Indian subcontinent. As has been noticed, several receiving stations placed during the VLF campaign in all over India, the VLF signal strength varies significantly with place and time. To understand the diurnal and seasonal variation of the received signal, a complete knowledge of physics of intensity distribution of the VLF signal is essential. The spatial variation of VLF signal plays an important role in selecting future VLF stations. In the wave-hop theoretical model presented here, horizontally stratified ionospheric layers have been considered. The VLF wave emitted by the transmitter has both the ground wave and the sky wave components. The ground wave attenuates during propagation. The sky wave component experiences reflections by the ionosphere on its way to the receiver and its attenuation depends on the degree of ionization. Intensity variation occurs at a given receiver location for interference among singly and multiply reflected waves. This has been simulated considering some simplified and justifiable assumptions. This spatial variation wave-hop theoretical model developed here has been compared with LWPC code generated results.

79 ASTRONOMY AND ASTROPHYSICS↗
DOE OSTI2011

Nuclear Physics Activities in Asia and ANPhA

On 18 July 2009 the Asian Nuclear Physics Association (ANPhA) has been officially launched in Beijing by the representatives from China, Korea, Japan and Vietnam. Since then Australia, India, Mongolia and Taiwan have joined to ANPhA and now the member country/region has increased to eight. Some activities and features on ANPhA are introduced. In addition, pleasant collaboration with Professor Arima by the author in regard to the Gamow-Teller quenching problem is also briefly mentioned.

73 NUCLEAR PHYSICS AND RADIATION PHYSICS↗
DOE OSTI2011

RF-Plasma Source Commissioning in Indian Negative Ion Facility

The Indian program of the RF based negative ion source has started off with the commissioning of ROBIN, the inductively coupled RF based negative ion source facility under establishment at Institute for Plasma research (IPR), India. The facility is being developed under a technology transfer agreement with IPP Garching. It consists of a single RF driver based beam source (BATMAN replica) coupled to a 100 kW, 1 MHz RF generator with a self excited oscillator, through a matching network, for plasma production and ion extraction and acceleration. The delivery of the RF generator and the RF plasma source without the accelerator, has enabled initiation of plasma production experiments. The recent experimental campaign has established the matching circuit parameters that result in plasma production with density in the range of 0.5-1x10{sup 18}/m{sup 3}, at operational gas pressures ranging between 0.4-1 Pa. Various configurations of the matching network have been experimented upon to obtain a stable operation of the set up for RF powers ranging between 25-85 kW and pulse lengths ranging between 4-20 s. It has been observed that the range of the parameters of the matching circuit, over which the frequency of the power supply is stable, is narrow and further experiments with increased number of turns in the coil are in the pipeline to see if the range can be widened. In this paper, the description of the experimental system and the commissioning data related to the optimisation of the various parameters of the matching network, to obtain stable plasma of required density, are presented and discussed.

43 PARTICLE ACCELERATORS↗
DOE OSTI2011

Characterization of Structural and Pigmentary Colors in Common Emigrant (Catopsilia Pomona) Butterfly

Study of structural colors in case of insects and butterflies is important for their biomimic and biophotonics applications. Structural color is the color which is produced by physical structures and their interaction with light while pigmentary color is produced by absorption of light by pigments. Common Emigrant butterfly is widely distributed in India. It is of moderate size with wing span of about 60-80 mm. The wings are broadly white with yellow or sulphur yellow coloration at places as well as few dark black patches. It belongs to family Pieridae. A study of structural color in case of Common Emigrant butterfly has been carried out in the present work. The characterization of wing color was performed using absorption spectroscopy. Scanning electron microscopic study of the wings of Common Emigrant butterfly showed that three different types of scales are present on the wing surface dorsally. Diffracting structures are present in certain parts of the surfaces of the various scales. Bead like structures are embedded in the intricate structures of the scales. Absorption spectra revealed that a strong absorption peak is seen in the UV-range. Crystalline structure of beads was confirmed by the X-ray diffraction analysis.

60 APPLIED LIFE SCIENCES↗
DOE OSTI2012

Indus synchrotron source: A national facility

Indus Synchrotron Radiation complex at Raja Ramanna Centre for Advanced Technology at Indore, India houses two synchrotron radiation sources: Indus-1 and Indus-2 respectively. Indus-1 is a 450 MeV source emitting in VUV and soft x-ray region and operating at 100 mA since 1990 and Indus-2, designed for 2.5 GeV, 300 mA and is currently operating at 2 GeV and 100 mA. Indus-1 has five operational beamlines while Indus-2 has six beamlines installed and operational. Several materials research related problems have been investigated using the reflectivity and photo-electron spectroscopy beamlines at Indus-1 and also the beamlines at Indus-2. Here we will report the current status of both these sources and discuss a few of our studies carried out using these beamlines.

43 PARTICLE ACCELERATORS↗
DOE OSTI2014

Cirrus cloud-temperature interactions over a tropical station, Gadanki from lidar and satellite observations

The cirrus clouds play an important role in the radiation budget of the earth's atmospheric system and are important to characterize their vertical structure and optical properties. LIDAR measurements are obtained from the tropical station Gadanki (13.5{sup 0} N, 79.2{sup 0} E), India, and meteorological indicators derived from Radiosonde data. Most of the cirrus clouds are observed near to the tropopause, which substantiates the strength of the tropical convective processes. The height and temperature dependencies of cloud height, optical depth, and depolarization ratio were investigated. Cirrus observations made using CALIPSO satellite are compared with lidar data for systematic statistical study of cirrus climatology.

54 ENVIRONMENTAL SCIENCES↗
DOE OSTI2015

Assessment of natural radioactivity concentrations and gamma dose levels around Shorapur, Karnataka

This study assesses the level of background radiation around Shorapur. The study region locates the western part of the Yadgir district of Karnataka. Shorapur and Shahapur talukas are mostly composed of clay, shale sandstone, granite rock and part of study area is black soil. Thirty sample locations were selected along the length and breadth of Shorapur and Shahapur taluka. Natural radionuclide activity concentrations in soil samples were determined using 4'X4' NaI (Tl) gamma spectroscopy. Outdoor gamma dose measurements in air at 1 m above ground level were determined using Rad Eye PRD survey meter. Estimated dose values are compared with the survey meter values and found to be good agreement between them and also with the data obtained from different other areas of Karnataka and India. The average values were found to be slightly higher in the present investigation.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗
DOE OSTI2015

Determination of elements in ayurvedic medicinal plants by AAS

India has a rich country for the uses of Ayurvedic medicinal plants for treatment and also the north- Karnataka boasts an unparallel diversity of medicinal plants. The present study attempts to estimate and compare the level of trace and heavy metals in some selected leaves and root samples of Ayurvedic medicinal plants such as Mg, Al, K, Cr, Mn, Fe, Cu, Zn, and Cd. The samples are collected from different places of North-Karnataka regions and sample solutions prepared as the ratio of 1:25:25+950ml=1000ppm.the trace and heavy elemental concentration was estimated using Atomic Absorption Spectrometric (AAS) Method. The average concentrations of Mg, Mn, Fe and Zn, are ranging from 2ppm to 5250.2ppm and potassium (K) has more concentration as compare to all other. The other elements likes Al, Cr, Cu, and Cd were also estimed and presented in the table. Therefore, these medicinal plants are rich in some essential minerals, especially K, Mg, Mn, Fe and Zn which are essential for human health.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗
DOE OSTI2015

Measurement of radon concentration in some water samples belonging to some adjoining areas of Pathankot, Punjab

The study of radon concentration was measured in some areas of Pathankot district, Punjab, India, from the health hazard point of view due to radon. The exposure to radon through drinking water is largely by inhalation and ingestion. RAD 7, an electronic solid state silicon detector (Durridgeco., USA) was used to measure the radon concentration in drinking water samples of the study area. The recorded values of radon concentration in these water samples are below the recommended limit by UNSCEAR and European commission. The recommended limit of radon concentration in water samples is 4 to 40 Bq/l given by UNSCEAR [1] and European commission has recommended the safe limit for radon concentration in water sample is 100 Bq/l [2].

54 ENVIRONMENTAL SCIENCES↗
DOE OSTI2016

Contribution of the conferences of the parties and the renewable energy role for the fight against climate change

The Kyoto Protocol, which entered into force on 16 February 2005, commits developed countries to reduce their emissions of greenhouse gases by 5% in 2012 compared to 1990. Due to the abstention of the United States and the absence of constraint on Southern countries, the protocol establishes obligations only to countries that represent only 33% of global CO{sub 2} emissions. All the diplomatic effort is therefore to seek the commitment of discussion for the period after 2012. The participation of the United States and emerging countries is imperative. The essential point of this second negotiation process is to search in the effort to integrate the United States and the developing countries and, more particularly, emerging economies such as China, India or Brazil, whose current emissions and / or projected should exceed those of developed countries during the first half of the twenty-first century. Real progress has been made in recent years. Indeed, a first universal historic agreement and legally binding was adopted after two weeks of intense negotiations by the Parties from 30 November to 12 December 2015, which aims to limit global warming by the end of this century well below 2 ° C while continuing efforts to not exceed 1.5 ° C. Moreover, the European Union, China and the United States have expressed their willingness to reduce their greenhouse gas. Because, one of the great hopes of the fight against the emission of greenhouse gases is the development of renewable energy, the IPCC (Intergovernmental Panel on Climate Change) report highlights the need to move towards renewable energy sources. The European Union, China and United States also expressed their willingness to increase the share of renewable energy. It is therefore necessary to develop the only inexhaustible energy, renewable energy, to fight against climate change.

54 ENVIRONMENTAL SCIENCES↗