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At least 595 records · Page 33

SU-F-BRF-14: Increasing the Accuracy of Dose Calculation On Cone-Beam Imaging Using Deformable Image Registration in the Case of Prostate Translation

Purpose: Artifacts can reduce the quality of dose re-calculations on CBCT scans during a treatment. The aim of this project is to correct the CBCT images in order to allow for more accurate and exact dose calculations in the case of a translation of the tumor in prostate cancer. Methods: Our approach is to develop strategies based on deformable image registration algorithms using the elastix software (Klein et al., 2010) to register the treatment planning CT on a daily CBCT scan taken during treatment. Sets of images are provided by a 3D deformable phantom and comprise two CT and two CBCT scans: one of both with the reference anatomy and the others with known deformations (i.e. translations of the prostate). The reference CT is registered onto the deformed CBCT and the deformed CT serves as the control for dose calculation accuracy. The planned treatment used for the evaluation of dose calculation is a 2-Gy fraction prescribed at the location of the reference prostate and assigned to 7 rectangular fields. Results: For a realistic 0.5-cm translation of the prostate, the relative dose discrepancy between the CBCT and the CT control scan at the prostate's centroid is 8.9 ± 0.8 % while dose discrepancy between the registered CT and the control scan lessens to −2.4 ± 0.8 %. For a 2-cm translation, clinical indices like the V90 and the D100 are more accurate by 0.7 ± 0.3 % and 8.0 ± 0.5 cGy respectively when using registered CT than when using CBCT for dose calculation. Conclusion: The results show that this strategy gives doses in agreement within a few percents with those from calculations on actual CT scans. In the future, various deformations of the phantom anatomy will allow a thorough characterization of the registration strategies needed for more complex anatomies.

60 APPLIED LIFE SCIENCES↗

Catalyst-layer ionomer imaging of fuel cells

Investigation of membrane/electrode assembly (MEA) microstructure has become an essential step to optimize the MEA components and manufacturing processes or to study the MEA degradation. For these investigations, transmission electron microscopy (TEM) is a tool of choice as it provides direct imaging of the different components. TEM is then widely used for analyzing the catalyst nanoparticles and their carbon support. However, the ionomer inside the electrode is more difficult to be imaged. The difficulties come from the fact that the ionomer forms an ultrathin layer surrounding the carbon particles and in addition, these two components, having similar density, present no difference in contrast. In this paper, we show how the recent progresses in TEM techniques as spherical aberration (Cs) corrected HRTEM, electron tomography and X-EDS elemental mapping provide new possibilities for imaging this ionomer network and consequently to study its degradation.

30 DIRECT ENERGY CONVERSION↗

High-resolution ptychographic imaging enabled by high-speed multi-pass scanning

As a coherent diffraction imaging technique, ptychography provides high-spatial resolution beyond Rayleigh’s criterion of the focusing optics, but it is also sensitively affected by the decoherence coming from the spatial and temporal variations in the experiment. Here we show that high-speed ptychographic data acquisition with short exposure can effectively reduce the impact from experimental variations. To reach a cumulative dose required for a given resolution, we further demonstrate that a continuous multi-pass scan via high-speed ptychography can achieve high-resolution imaging. This low-dose scan strategy is shown to be more dose-efficient, and has potential for radiation-sensitive sample studies and time-resolved imaging.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Toward inverse backscatter absorption gas imaging: imaging a dry gas plume with ambient H 2 O absorption

This paper introduces inverse backscatter absorption gas imaging (iBAGI), a transparent gas imaging technique based on absorption spectroscopy of gases naturally present in ambient air being displaced by transparent gases. We demonstrate reconstruction of a 2-D image of a dry gas plume by measuring light of a raster-scanned diode laser tuned to an absorption line of atmospheric H 2 O. We quantify the performance depending on the distance to the backdrop and show that the key transmission metric is independent of absorption path length. We conclude with an outlook toward calibration-free, single-ended iBAGI using scattering from low-reflectivity backdrops.

Klug, Joseph C.↗

Commercial Opportunity Cancer Imaging Ultrasonics-based methods for cancer imaging & diagnostics

Breast cancer is the most frequently diagnosed cancer in U.S. women and prostate cancer is the second leading cause of cancer death in American men. X-ray mammography is the principal breastcancer screening tool available, but its false positive rate is more than 80%. Prostate-specific antigen (PSA) screening, which measures the level of PSA in a man’s blood, is no longer recommended by the U.S. task force for prostate-cancer screening. Los Alamos National Security (LANS) has developed novel imaging technologies for early-stage cancer detection based on advanced ultrasonic analyses. In particular, Los Alamos has developed ultrasoundwaveform tomography and related super-resolution ultrasound- imaging technologies that can provide significantly improved image resolution and characterization of early-stage cancers and thus potentially save lives.

60 APPLIED LIFE SCIENCES↗

Limited-view 3D Imaging Technology or “LV 3D Imaging” Technology Assessment

Limited View 3D or “LV 3D” imaging is important because it addresses a technology gap that has life, time, radiation dose and monetary-saving impacts. It provides something that currently does not exist and its potential products open a variety of technology domains in which SRNL could become competitive in. It can become a low cost, safer and alternative approach to conducting what is commonly referred to as computer tomographic imaging. This project develops a bucket list of technologies that will be needed to develop a portable system for conducting LV 3D imaging.

47 OTHER INSTRUMENTATION↗

Limited-view 3D Imaging Technology or “LV 3D Imaging” Technology Assessment

Limited View 3D or “LV 3D” imaging is important because it addresses a tech nology gap that has life, time, radiation dose and monetary-saving impacts. It provides something that currently does not exist and its potential products open a variety of technology domains in which SRNL could become competitive in. It can become a low cost, safer and alternative approach to conducting what is commonly referred to as computer tomographic imaging. This project develops a bucket list of technologies that will be needed to develop a portable system for conducting LV 3D imaging.

47 OTHER INSTRUMENTATION↗

Cloud Particle Imager (CPI) and 3-View Cloud Particle Imager (3V-CPI) Instrument Handbook

The cloud particle imager (CPI) is a U.S. Department of Energy (DOE) Atmospheric Radiation Measurement (ARM) user facility instrument for measuring the concentration and size of cloud droplet and ice crystals. Hydrometeors entering the tube will be detected by a system of two continuous wave lasers that are perpendicular to each other, monitoring the sample volume. When a hydrometeor obscures both laser beams it is inside the sample volume and a third laser is triggered to illuminate the hydrometeor and a camera records a two-dimensional image. The CPI records images with a resolution of 2.3 μm. Since the camera has 1024 x 1024 pixels, the maximum detectable size is 2.3 mm x 2.3 mm.

54 ENVIRONMENTAL SCIENCES↗

Combining hyperspectral imaging and micro-X-ray fluorescence imaging methods for ultra-high-resolution biogeochemical analysis

Current non-destructive methods for high-resolution geochemical imaging open new avenues for high-resolution paleoenvironmental research. We discuss how two of these methods, hyperspectral imaging and micro-X-ray fluorescence imaging, can be combined for organic and inorganic geochemical analyses at a micrometer scale.

Zander, Paul [Lawrence Livermore National Laborato↗

Supplementary material for manuscript: Microcomputed X-ray Tomographic Imaging and Image Processing for Microstructural Characterization of Explosives

This data contains the supplemental information that will be accessible to the public from the paper “Microcomputed X-ray Tomographic Imaging and Image Processing for Microstructural Characterization of Explosives”. The data set contains the reconstructed slices for the 3D images of three different high explosives including: HMX-HTPB, PBX 9501 and PBX 9502. The data sets are folders of reconstructed tiffs showing the microstructure (crystals, binder, voids) and a segmented data set of each. Finally, a .gif movie is also present that plays the slices sequentially. The folders contain the voxel size information. See the manuscript for more details.

36 MATERIALS SCIENCE↗

THE LEECH EXOPLANET IMAGING SURVEY: CHARACTERIZATION OF THE COLDEST DIRECTLY IMAGED EXOPLANET, GJ 504 b, AND EVIDENCE FOR SUPERSTELLAR METALLICITY

As gas giant planets and brown dwarfs radiate away the residual heat from their formation, they cool through a spectral type transition from L to T, which encompasses the dissipation of cloud opacity and the appearance of strong methane absorption. While there are hundreds of known T-type brown dwarfs, the first generation of directly imaged exoplanets were all L type. Recently, Kuzuhara et al. announced the discovery of GJ 504 b, the first T dwarf exoplanet. GJ 504 b provides a unique opportunity to study the atmosphere of a new type of exoplanet with a ∼500 K temperature that bridges the gap between the first directly imaged planets (∼1000 K) and our own solar system's Jupiter (∼130 K). We observed GJ 504 b in three narrow L-band filters (3.71, 3.88, and 4.00 μm), spanning the red end of the broad methane fundamental absorption feature (3.3 μm) as part of the LBTI Exozodi Exoplanet Common Hunt (LEECH) exoplanet imaging survey. By comparing our new photometry and literature photometry with a grid of custom model atmospheres, we were able to fit GJ 504 b's unusual spectral energy distribution for the first time. We find that GJ 504 b is well fit by models with the following parameters: T{sub eff} = 544 ± 10 K, g < 600 m s{sup −2}, [M/H] = 0.60 ± 0.12, cloud opacity parameter of f{sub sed} = 2–5, R = 0.96 ± 0.07 R{sub Jup}, and log(L) = −6.13 ± 0.03 L{sub ⊙}, implying a hot start mass of 3–30 M{sub jup} for a conservative age range of 0.1–6.5 Gyr. Of particular interest, our model fits suggest that GJ 504 b has a superstellar metallicity. Since planet formation can create objects with nonstellar metallicities, while binary star formation cannot, this result suggests that GJ 504 b formed like a planet, not like a binary companion.

79 ASTRONOMY AND ASTROPHYSICS↗

Direct Imaging of the HD 35841 Debris Disk: A Polarized Dust Ring from Gemini Planet Imager and an Outer Halo from HST/STIS

In this work, we present new high resolution imaging of a light-scattering dust ring and halo around the young star HD 35841. Using spectroscopic and polarimetric data from the Gemini Planet Imager in H-band (1.6 μm), we detect the highly inclined (i = 85°) ring of debris down to a projected separation of ~12 au (~0farcs12) for the first time. Optical imaging from HST/STIS shows a smooth dust halo extending outward from the ring to >140 au (>1farcs4). We measure the ring's scattering phase function and polarization fraction over scattering angles of 22°–125°, showing a preference for forward scattering and a polarization fraction that peaks at ~30% near the ansae. Modeling of the scattered-light disk indicates that the ring spans radii of ~60–220 au, has a vertical thickness similar to that of other resolved dust rings, and contains grains as small as 1.5 μm in diameter. These models also suggest the grains have a low porosity, are more likely to consist of carbon than astrosilicates, and contain significant water ice. The halo has a surface brightness profile consistent with that expected from grains pushed by radiation pressure from the main ring onto highly eccentric but still bound orbits. We also briefly investigate arrangements of a possible inner disk component implied by our spectral energy distribution models, and speculate about the limitations of Mie theory for doing detailed analyses of debris disk dust populations.

79 ASTRONOMY AND ASTROPHYSICS↗

A Uniform Analysis of Debris Disks with the Gemini Planet Imager. I. An Empirical Search for Perturbations from Planetary Companions in Polarized Light Images

The Gemini Planet Imager (GPI) has excelled in imaging debris disks in the near-infrared. The GPI Exoplanet Survey imaged 24 debris disks in polarized H-band light, while other programs observed half of these disks in polarized J and/or K1 bands. Using these data, we present a uniform analysis of the morphology of each disk to find asymmetries suggestive of perturbations, particularly those due to planet–disk interactions. The multiwavelength surface brightness, disk color, and geometry permit the identification of any asymmetries such as warps or disk offsets from the central star. We find that 19 of the disks in this sample exhibit asymmetries in surface brightness, disk color, disk geometry, or a combination of the three, suggesting that for this sample, perturbations, as seen in scattered light, are common. The relationship between these perturbations and potential planets in the system is discussed. We also explore correlations among stellar temperatures, ages, disk properties, and observed perturbations. We find significant trends between the vertical aspect ratio and the stellar temperature, disk radial extent, and the dust grain size distribution power law, q. We also confirm a trend between the disk color and stellar effective temperature, where the disk becomes increasingly red/neutral with increasing temperature. Such results have important implications for the evolution of debris disk systems around stars of various spectral types.

79 ASTRONOMY AND ASTROPHYSICS↗

X-ray and gamma-ray imaging with multiple-pinhole cameras using a posteriori image synthesis.

In 1968, Dicke had suggested that multiple-pinhole camera systems would have significant advantages concerning the SNR in X-ray and gamma-ray astronomy if the multiple images could be somehow synthesized into a single image. The practical development of an image-synthesis method based on these suggestions is discussed. A formulation of the SNR gain theory which is particularly suited for dealing with the proposal by Dicke is considered. It is found that the SNR gain is by no means uniform in all X-ray astronomy applications.

Groh, G.↗

Parametric analysis of an imaging radar for use as an imaging radar for use as an independent landing monitor

The capabilities are analyzed of a real aperture, forward-looking imaging radar for use as an independent landing monitor, which will provide the pilot with an independent means of assessing the progress of an automatic landing during Category 3 operations. The analysis shows that adequate ground resolution and signal-to-noise ratio can be obtained to image a runway with grassy surroundings using a radar operating at 35 GHz in good weather and in most fog but that performance is severely degraded in moderate to heavy rain and wet snow. Weather effects on a 10 GHz imager are not serious, with the possible exception of very heavy rain, but the azimuthal resolution at 10 GHz is inadequate with antennas up to 2 m long.

Bundick, W. T.↗

Application of ERTS images and image processing to regional geologic problems and geologic mapping in northern Arizona

The author has identified the following significant results. Computer image processing was shown to be both valuable and necessary in the extraction of the proper subset of the 200 million bits of information in an ERTS image to be applied to a specific problem. Spectral reflectivity information obtained from the four MSS bands can be correlated with in situ spectral reflectance measurements after path radiance effects have been removed and a proper normalization has been made. A detailed map of the major fault systems in a 90,000 sq km area in northern Arizona was compiled from high altitude photographs and pre-existing published and unpublished map data. With the use of ERTS images, three major fault systems, the Sinyala, Bright Angel, and Mesa Butte, were identified and their full extent measured. A byproduct of the regional studies was the identification of possible sources of shallow ground water, a scarce commodity in these regions.

Goetz, A. F. H.↗