Engineering Papers⌕ Search

SEARCH · Engineering Papers

Results for “FRED”

Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 595 records · Page 33
All sourcesNASA NTRSDOE OSTI
DOE OSTI2016

Continued emissions of carbon tetrachloride from the United States nearly two decades after its phaseout for dispersive uses

National-scale emissions of carbon tetrachloride (CCl 4 ) are derived based on inverse modeling of atmospheric observations at multiple sites across the United States from the National Oceanic and Atmospheric Administration's flask air sampling network. We estimate an annual average US emission of 4.0 (2.0-6.5) Gg CCl 4 y -1 during 2008- 2012, which is almost two orders of magnitude larger than reported to the US Environmental Protection Agency (EPA) Toxics Release Inventory (TRI) (mean of 0.06 Gg y -1 ) but only 8% (3-22%) of global CCl 4 emissions during these years. Emissive regions identified by the observations and consistently shown in all inversion results include the Gulf Coast states, the San Francisco Bay Area in California, and the Denver area in Colorado. Both the observation-derived emissions and the US EPA TRI identified Texas and Louisiana as the largest contributors, accounting for one- to two-thirds of the US national total CCl 4 emission during 2008-2012. These results are qualitatively consistent with multiple aircraft and ship surveys conducted in earlier years, which suggested significant enhancements in atmospheric mole fractions measured near Houston and surrounding areas. Furthermore, the emission distribution derived for CCl 4 throughout the United States is more consistent with the distribution of industrial activities included in the TRI than with the distribution of other potential CCl 4 sources such as uncapped landfills or activities related to population density (e.g., use of chlorine-containing bleach).

54 ENVIRONMENTAL SCIENCES↗
DOE OSTI2016

A remotely sensed pigment index reveals photosynthetic phenology in evergreen conifers

In evergreen conifers, where the foliage amount changes little with season, accurate detection of the underlying “photosynthetic phenology” from satellite remote sensing has been difficult, presenting challenges for global models of ecosystem carbon uptake. In this paper, we report a close correspondence between seasonally changing foliar pigment levels, expressed as chlorophyll/carotenoid ratios, and evergreen photosynthetic activity, leading to a “chlorophyll/carotenoid index” (CCI) that tracks evergreen photosynthesis at multiple spatial scales. When calculated from NASA’s Moderate Resolution Imaging Spectroradiometer satellite sensor, the CCI closely follows the seasonal patterns of daily gross primary productivity of evergreen conifer stands measured by eddy covariance. This discovery provides a way of monitoring evergreen photosynthetic activity from optical remote sensing, and indicates an important regulatory role for carotenoid pigments in evergreen photosynthesis. Improved methods of monitoring photosynthesis from space can improve our understanding of the global carbon budget in a warming world of changing vegetation phenology.

59 BASIC BIOLOGICAL SCIENCES↗
DOE OSTI2016

Dopaminergic inputs in the dentate gyrus direct the choice of memory encoding

Rewarding experiences are often well remembered, and such memory formation is known to be dependent on dopamine modulation of the neural substrates engaged in learning and memory; however, it is unknown how and where in the brain dopamine signals bias episodic memory toward preceding rather than subsequent events. Here we found that photostimulation of channelrhodopsin-2–expressing dopaminergic fibers in the dentate gyrus induced a long-term depression of cortical inputs, diminished theta oscillations, and impaired subsequent contextual learning. Computational modeling based on this dopamine modulation indicated an asymmetric association of events occurring before and after reward in memory tasks. In subsequent behavioral experiments, preexposure to a natural reward suppressed hippocampus-dependent memory formation, with an effective time window consistent with the duration of dopamine-induced changes of dentate activity. Altogether, our results suggest a mechanism by which dopamine enables the hippocampus to encode memory with reduced interference from subsequent experience.

59 BASIC BIOLOGICAL SCIENCES↗
DOE OSTI2022

Omicron mutations enhance infectivity and reduce antibody neutralization of SARS-CoV-2 virus-like particles

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant contains extensive sequence changes relative to the earlier-arising B.1, B.1.1, and Delta SARS-CoV-2 variants that have unknown effects on viral infectivity and response to existing vaccines. Using SARS-CoV-2 virus-like particles (VLPs), we examined mutations in all four structural proteins and found that Omicron and Delta showed 4.6-fold higher luciferase delivery overall relative to the ancestral B.1 lineage, a property conferred mostly by enhancements in the S and N proteins, while mutations in M and E were mostly detrimental to assembly. Thirty-eight antisera samples from individuals vaccinated with Pfizer/BioNTech, Moderna, or Johnson & Johnson vaccines and convalescent sera from unvaccinated COVID-19 survivors had 15-fold lower efficacy to prevent cell transduction by VLPs containing the Omicron mutations relative to the ancestral B.1 spike protein. A third dose of Pfizer vaccine elicited substantially higher neutralization titers against Omicron, resulting in detectable neutralizing antibodies in eight out of eight subjects compared to one out of eight preboosting. Furthermore, the monoclonal antibody therapeutics casirivimab and imdevimab had robust neutralization activity against B.1 and Delta VLPs but no detectable neutralization of Omicron VLPs, while newly authorized bebtelovimab maintained robust neutralization across variants. Our results suggest that Omicron has similar assembly efficiency and cell entry compared to Delta and that its rapid spread is due mostly to reduced neutralization in sera from previously vaccinated subjects. In addition, most currently available monoclonal antibodies will not be useful in treating Omicron-infected patients with the exception of bebtelovimab.

59 BASIC BIOLOGICAL SCIENCES↗
DOE OSTI2025

High-temperature anomalous Hall effect driven by frustrated spin fluctuations in the antiferromagnetic delafossite metal PdCrO 2

Metallic delafossite oxides are of exceptional interest due to their ultraclean metallic transport. In the case of PdCrO 2 , this arises in a triangular-lattice antiferromagnet, creating a unique opportunity to study frustrated magnetism in a very clean metal. Here, we combine a chemical vapor transport crystal growth approach with magnetic, thermodynamic, magnetotransport, and neutron scattering measurements to elucidate the striking anomalous Hall effect (AHE) in antiferromagnetic PdCrO 2 . The unconventional AHE (with anomalous Hall conductivity ~10 5 Ω −1 cm −1 ) and a large positive magnetoresistance effect (>1,000%) are shown to exhibit complex temperature dependencies, persisting to almost seven times the Néel temperature (~250 K). These effects are directly compared to elastic neutron scattering, inelastic neutron scattering, and neutron magnetic pair distribution function data, establishing unambiguous links between anomalous magnetotransport properties and directly probed short-range spin fluctuations. The latter occur over a notably broad temperature range due to geometrical magnetic frustration. Connecting to recent experimental and theoretical developments, these findings are discussed in terms of a temperature-dependent interplay between chiral spin order and chiral spin fluctuations, significantly elucidating the high-temperature anomalous magnetotransport in such compounds.

anomalous Hall effect↗
DOE OSTI2013

Comparative phosphoproteomics reveals components of host cell invasion and post-transcriptional regulation during Francisella infection

Francisella tularensis is a facultative intracellular bacterium that causes the deadly disease tularemia. Most evidence suggests that Francisella is not well recognized by the innate immune system that normally leads to cytokine expression and cell death. In previous work, we identified new bacterial factors that were hyper-cytotoxic to macrophages. Four of the identified hyper-cytotoxic strains (lpcC, manB, manC and kdtA) had an impaired lipopolysaccharide (LPS) synthesis and produced an exposed lipid A lacking the O-antigen. These mutants were not only hyper-cytotoxic but also were phagocytosed at much higher rates compared to the wild type parent strain. To elucidate the cellular signaling underlying this enhanced phagocytosis and cell death, we performed a large-scale comparative phosphoproteomic analysis of cells infected with wild-type and delta-lpcC F. novicida. Our data suggest that not only actin but also intermediate filaments and microtubules are important for F. novicida entry into the host cells. In addition, we observed differential phosphorylation of tristetraprolin (TTP), a key component of the mRNA-degrading machinery that controls the expression of a variety of genes including many cytokines. Infection with the delta-lpcC mutant induced the hyper-phosphorylation and inhibition of TTP, leading to the production of cytokines such as IL-1beta and TNF-alpha which may kill the host cells by triggering apoptosis. Together, our data provide new insights for Francisella invasion and a post-transcriptional mechanism that prevents the expression of host immune response factors that controls infection by this pathogen.

Environmental Molecular Sciences Laboratory↗
DOE OSTI2023

Application of MELCOR for Simulating Molten Salt Reactor Accident Source Terms

Molten Salt Reactor (MSR) systems can be divided into two basic categories: liquid-fueled MSRs in which the fuel is dissolved in the salt, and solid-fueled systems such as the Fluoride-salt-cooled High-temperature Reactor (FHR). The molten salt provides an impediment to fission product release as actinides and many fission products are soluble in molten salt. Nonetheless, under accident conditions, some radionuclides may escape the salt by vaporization and aerosol formation, which may lead to release into the environment. Here, we present recent enhancements to MELCOR to represent the transport of radionuclides in the salt and releases from the salt. Some soluble but volatile radionuclides may vaporize and subsequently condense to aerosol. Insoluble fission products can deposit on structures. Thermochimica, an open-source Gibbs Energy Minimization (GEM) code, has been integrated into MELCOR. With the appropriate thermochemical database, Thermochimica provides the solubility and vapor pressure of species as a function of temperature, pressure, and composition, which are needed to characterize the vaporization rate and the state of the salt with fission products. Since thermochemical databases are still under active development for molten salt systems, thermodynamic data for fission product solubility and vapor pressure may be user specified. This enables preliminary assessments of fission product transport in molten salt systems. In this paper, we discuss modeling of soluble and insoluble fission product releases in a MSR with Thermochimica incorporated into MELCOR. Separate-effects experiments performed as part of the Molten Salt Reactor Experiment in which radioactive aerosol was released are discussed as needed for determining the source term.

21 SPECIFIC NUCLEAR REACTORS AND ASSOCIATED PLANTS↗
DOE OSTI2026

Evaluation of a catalytically aided thermal regeneration method for quartz filter-based black carbon sensing

Black carbon (BC)–a strong indicator of diesel particulate matter and other sources of incomplete carbonaceous fuel combustion–is an important air pollutant that affects public health, yet low-cost sensors capable of long-term, autonomous BC monitoring remain underdeveloped. We report on the development and evaluation of a novel BC prototype sensor that integrates soot collection on a quartz filter, in-situ optical transmission measurement, and thermal filter regeneration. To enable regeneration at lower temperatures, we evaluated the catalytic effects of various alkali metal salts pre-applied to the filter. Among these, cesium carbonate (Cs 2 CO 3 ) exhibited the strongest catalytic activity, lowering the temperature required for complete BC removal by up to 190 °C and reducing energy consumption by more than 75% compared to that required for untreated filters. The catalytic effect persisted through 10 BC collection–regeneration cycles. These findings demonstrate the potential of catalytically aided thermal regeneration in BC sensors and suggest a pathway toward energy-efficient and reduced maintenance air quality monitoring suitable for distributed BC monitoring networks.

Tang, Xiaochen [Lawrence Berkeley National Laborat↗
DOE OSTI2017

The Influence of Microstructure on Deuterium Retention in Polycrystalline Tungsten

The retention of hydrogen isotopes in the plasma-facing materials of a fusion reactor is dependent on the density of trapping sites in the material. One factor that can influence the trapping defects is the surface state of the material before exposure. Mechanically polished, electropolished, and recrystallized tungsten samples were compared by exposing them to 350 eV D + beams with peak fluences of ~1 × 10 24 D + /m 2 at 500 and 740 K at the Multicharged Ion Research Facility (MIRF). At the exposure temperature of 740 K, no significant retention was detected. For material exposed at 500 K, significant differences in retention were observed, and the order of increasing retention was recrystallized, electropolished, and mechanically polished. Lastly, the other variable besides surface treatment was the time delay between ion exposure and thermal desorption spectroscopy which also may have impacted the retention measurements if there was out-gassing of the D while samples were in storage before thermal desorption spectroscopy (TDS).

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗
DOE OSTI2023

Previous exposure to Spike-providing parental strains confers neutralizing immunity to XBB lineage and other SARS-CoV-2 recombinants in the context of vaccination

The emergence of SARS-CoV-2 recombinants is of particular concern as they can result in a sudden increase in immune evasion due to antigenic shift. Recent recombinants XBB and XBB.1.5 have higher transmissibility than previous recombinants such as “Deltacron.” We hypothesized that immunity to a SARS-CoV-2 recombinant depends on prior exposure to its parental strains. To test this hypothesis, we examined whether Delta or Omicron (BA.1 or BA.2) immunity conferred through infection, vaccination, or breakthrough infection could neutralize Deltacron and XBB/XBB.1.5 recombinants. We found that Delta, BA.1, or BA.2 breakthrough infections provided better immune protection against Deltacron and its parental strains than did the vaccine booster. None of the sera were effective at neutralizing the XBB lineage or its parent BA.2.75.2, except for the sera from the BA.2 breakthrough group. These results support our hypothesis. In turn, our findings underscore the importance of multivalent vaccines that correspond to the antigenic profile of circulating variants of concern and of variant-specific diagnostics that may guide public health and individual decisions in response to emerging SARS-CoV-2 recombinants.

59 BASIC BIOLOGICAL SCIENCES↗
DOE OSTI2012

PLANETARY CONSTRUCTION ZONES IN OCCULTATION: DISCOVERY OF AN EXTRASOLAR RING SYSTEM TRANSITING A YOUNG SUN-LIKE STAR AND FUTURE PROSPECTS FOR DETECTING ECLIPSES BY CIRCUMSECONDARY AND CIRCUMPLANETARY DISKS

The large relative sizes of circumstellar and circumplanetary disks imply that they might be seen in eclipse in stellar light curves. We estimate that a survey of {approx}10{sup 4} young ({approx}10 million year old) post-accretion pre-main-sequence stars monitored for {approx}10 years should yield at least a few deep eclipses from circumplanetary disks and disks surrounding low-mass companion stars. We present photometric and spectroscopic data for a pre-main-sequence K5 star (1SWASP J140747.93-394542.6 = ASAS J140748-3945.7), a newly discovered {approx}0.9 M{sub Sun} member of the {approx}16 Myr old Upper Centaurus-Lupus subgroup of Sco-Cen at a kinematic distance of 128 {+-} 13 pc. This star exhibited a remarkably long, deep, and complex eclipse event centered on 2007 April 29 (as discovered in Super Wide Angle Search for Planets (SuperWASP) photometry, and with portions of the dimming confirmed by All Sky Automated Survey (ASAS) data). At least five multi-day dimming events of >0.5 mag are identified, with a >3.3 mag deep eclipse bracketed by two pairs of {approx}1 mag eclipses symmetrically occurring {+-}12 days and {+-}26 days before and after. Hence, significant dimming of the star was taking place on and off over at least a {approx}54 day period in 2007, and a strong >1 mag dimming event occurring over a {approx}12 day span. We place a firm lower limit on the period of 850 days (i.e., the orbital radius of the eclipser must be >1.7 AU and orbital velocity must be <22 km s{sup -1}). The shape of the light curve is similar to the lopsided eclipses of the Be star EE Cep. We suspect that this new star is being eclipsed by a low-mass object orbited by a dense inner disk, further girded by at least three dusty rings of optical depths near unity. Between these rings are at least two annuli of near-zero optical depth (i.e., gaps), possibly cleared out by planets or moons, depending on the nature of the secondary. For possible periods in the range 2.33-200 yr, the estimated total ring mass is {approx}8-0.4 M{sub Moon} (if the rings have optical opacity similar to Saturn's rings), and the edge of the outermost detected ring has orbital radius {approx}0.4-0.09 AU. In the new era of time-domain astronomy opened by surveys like SuperWASP, ASAS, etc., and soon to be revolutionized by Large Synoptic Survey Telescope, discovering and characterizing eclipses by circumplanetary and circumsecondary disks will provide us with observational constraints on the conditions that spawn satellite systems around gas giant planets and planetary systems around stars.

79 ASTRONOMY AND ASTROPHYSICS↗
DOE OSTI2012

INVISIBLE ACTIVE GALACTIC NUCLEI. I. SAMPLE SELECTION AND OPTICAL/NEAR-IR SPECTRAL ENERGY DISTRIBUTIONS

In order to find more examples of the elusive high-redshift molecular absorbers, we have embarked on a systematic discovery program for highly obscured, radio-loud 'invisible active galactic nuclei' using the Very Large Array Faint Images of the Radio Sky at Twenty centimeters radio survey in conjunction with the Sloan Digital Sky Survey (SDSS) to identify 82 strong ({>=}300 mJy) radio sources positionally coincident with late-type, presumably gas-rich galaxies. In this first paper, the basic properties of this sample are described including the selection process and the analysis of the spectral energy distributions (SEDs) derived from the optical (SDSS) + near-IR (NIR) photometry obtained by us at the Apache Point Observatory 3.5 m. The NIR images confirm the late-type galaxy morphologies found by SDSS for these sources in all but a few (6 of 70) cases (12 previously well studied or misclassified sources were culled). Among 70 sources in the final sample, 33 show galaxy type SEDs, 17 have galaxy components to their SEDs, and 20 have quasar power-law continua. At least nine sources with galaxy SEDs have K-band flux densities too faint to be giant ellipticals if placed at their photometric redshifts. Photometric redshifts for this sample are analyzed and found to be too inaccurate for an efficient radio-frequency absorption line search; spectroscopic redshifts are required. A few new spectroscopic redshifts for these sources are presented here but more will be needed to make significant progress in this field. Subsequent papers will describe the radio continuum properties of the sample and the search for redshifted H I 21 cm absorption.

79 ASTRONOMY AND ASTROPHYSICS↗