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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 595 records · Page 33

Systems identification and application systems development for monitoring the physiological and health status of crewmen in space

The use of automated, analytical techniques to aid medical support teams is suggested. Recommendations are presented for characterizing crew health in terms of: (1) wholebody function including physiological, psychological and performance factors; (2) a combination of critical performance indexes which consist of multiple factors of measurable parameters; (3) specific responses to low noise level stress tests; and (4) probabilities of future performance based on present and periodic examination of past performance. A concept is proposed for a computerized real time biomedical monitoring and health care system that would have the capability to integrate monitored data, detect off-nominal conditions based on current knowledge of spaceflight responses, predict future health status, and assist in diagnosis and alternative therapies. Mathematical models could play an important role in this approach, especially when operating in a real time mode. Recommendations are presented to update the present health monitoring systems in terms of recent advances in computer technology and biomedical monitoring systems.

Leonard, J. I.↗

Improvements and validation of the erythropoiesis control model for bed rest simulation

The most significant improvement in the model is the explicit formulation of separate elements representing erythropoietin production and red cell production. Other modifications include bone marrow time-delays, capability to shift oxyhemoglobin affinity and an algorithm for entering experimental data as time-varying driving functions. An area of model development is suggested by applying the model to simulating onset, diagnosis and treatment of a hematologic disorder. Recommendations for further improvements in the model and suggestions for experimental application are also discussed. A detailed analysis of the hematologic response to bed rest including simulation of the recent Baylor Medical College bed rest studies is also presented.

Leonard, J. I.↗

Telemetry of intracranial pressure

A completely implantable epidural pressure telemetry system designed for accurate measurement of intracranial pressure (ICP) is described. The implant device is batteryless, providing unlimited operating life. The described system uses a capacitive pressure transducer with excellent long-term stability. Once detected with the transducer and converted to a frequency with the oscillator electronics, the pressure signal is digitized. It is then telemetered without the possibility of further degradation. After detection with the small external module, the data can be retransmitted by a radio link for complete patient mobility or the energizer signal pickup module can be wired to a bedside readout unit. Continuous data are available from the system so that the dynamic ICP changes reflecting arterial blood pressure can be observed and used for diagnosis.

Fryer, T. B.↗

Portable high-resolution laser monochromator-interferometer with multichannel electronic readout

A high-resolution 0.4-m monochromator is described for use in wavelength diagnosis of tunable pulsed and CW laser sources in the 3000-10,000-A region. The f/20 design uses an echelle grating in an over-and-under Ebert configuration with a scanned photodiode array to provide a real-time multichannel display of spectral output. Absolute wavelength may be determined to 0.1 A with the monochromator, and a Fabry-Perot interferometer attachment extends linewidth measurement capability to 0.01 A or better. Spectra are displayed on a storage oscilloscope, and calculation of laser parameters is explained. The instrument measures 70 cm long x 15 cm wide x 20 cm high.

Morris, M. B.↗

Experimental shock metamorphism of mono- and polycrystalline olivine - A comparative study

The paper reports on a series of controlled shock recovery experiments which have been performed on over 40 samples including monocrystalline, polycrystalline, dunite, and porous particulate olivine-bearing targets. Results of the mineralogical and petrological analyses of these samples are used to establish a general and comparative diagnosis of shock effects generated in various olivine-bearing materials. Finally, some experiments are conducted under different ambient pO2 conditions so that information on the distribution of observed impact features is derived as a function not only of peak pressure and texture of the target sample, but also of specific environmental conditions.

Bauer, J. F.↗

The soft X-ray polychromator for the Solar Maximum Mission

The paper considers the soft X-ray polychromator (XRP) operating in the 1.4-22.4 A range of the soft X-ray spectrum which includes many emission lines important for the diagnosis of plasmas in the 1.5-50 million deg temperature range. The flat crystal scanning spectrometer provides for a channel polychromatic mapping of flares and active regions in the resonance lines of O VIII, Ne IX, and Mg XI; in its spectral scanning mode it covers essentially the entire 1.4-22.5 A region.

Acton, L. W.↗

Immunomicrospheres - Reagents for cell labeling and separation

Immunomicrospheres are specially designed microscopic particles that have antibodies or similar molecules chemically bound to their surfaces. The antibody-coated microspheres react in a highly specific way with target cells, viruses, or other antigenic agents. Immunomicrospheres may be synthesized so that they incorporate compounds that are highly radioactive, intensely fluorescent, magnetic, electron opaque, highly colored, or pharmacologically active. These various types of microspheres may be coated with pure, highly specific monoclonal antibodies obtained by the new hybridoma cell cloning techniques or with conventional antibody preparations. Some of the many present and potential applications for these new reagents are (1) new types of radioimmune or immunofluorescent assays, (2) improved fluorescence microscopy, (3) separation of cells on the basis of the fluorescent, electrophoretic, or magnetic properties of bound immunomicrospheres, (4) markers for use in several types of electron or standard light microscopy, and (5) delivery of lethal compouds to specific undesirable living cells. The combination of the various new types of synthetic microspheres and the newly available homogeneous antibodies offers new opportunities in research, diagnosis, and therapy.

Rembaum, A.↗

Particle acceleration by propagating interplanetary shocks

The process of charged particle acceleration in interplanetary shocks has been simulated for typical parameters. Since space probe observations of charged particle fluxes are the principle means of inferring the action of an acceleration mechanism, the simulation was designed to follow particles backwards in time from a given observing point, usually 1 AU. This allowed a full diagnosis of which observed particles had interacted with an oncoming shock, where the interacting occurred, and by how much the energy had been changed by the shock interaction. Simple assumptions about the preshock energy spectrum allow the construction of a full temporal profile of the expected intensity, anisotropy, and energy spectrum. The simulations are apparently capable of reproducing the main features of the less than 10 MeV/nuc ion flux enhancements observed at interplanetary shocks using only a laminar interplanetary magnetic field, Archimidean spiral, and a spherical oblique shock with typical speed, strength, and shock normal-magnetic field angle.

Armstrong, T. P.↗

Genesis of breath sounds-Preliminary verification of theory

Experimental results are presented which tend to validate a previously developed theory of sound production in the human lung over a particular Reynolds number range. In addition, a new, presently nonunderstood, phenomenon was observed at higher Reynolds number. These results, which show how sound generation in the lung depends upon the physiologically important variables of volume flow rate and bronchial diameter, have potentially important application in noninvasive lung examination and the diagnosis of lung disease.

Patterson, J. L.↗

Orthostatic hypotension

Following a brief physiopathological review, orthostatic hypotension is classified into three groups: organic, functional and medication-dependent. The importance of etiological diagnosis, the use of objective tests and appropriate therapy, especially concerning the organic forms, is stressed.

Grimm, J. J.↗

Monitoring and decision making by people in man machine systems

The analysis of human monitoring and decision making behavior as well as its modeling are described. Classic and optimal control theoretical, monitoring models are surveyed. The relationship between attention allocation and eye movements is discussed. As an example of applications, the evaluation of predictor displays by means of the optimal control model is explained. Fault detection involving continuous signals and decision making behavior of a human operator engaged in fault diagnosis during different operation and maintenance situations are illustrated. Computer aided decision making is considered as a queueing problem. It is shown to what extent computer aids can be based on the state of human activity as measured by psychophysiological quantities. Finally, management information systems for different application areas are mentioned. The possibilities of mathematical modeling of human behavior in complex man machine systems are also critically assessed.

Johannsen, G.↗

Skylab: Cytogenetic studies of blood (experiment mill)

Preflight and postflight chromosomal analyses of space flight crews are presented. Special attention is given to findings suggestive of exposure to ionizing radiation. Information was obtained by study of persons receiving an external body source, such as, therapeutic dosage or those accidentally exposed. Others receiving radiation exposure from an internal source, such as the decay of radioisotopes administered for diagnosis or treatment, were also analyzed.

Lockhart, L. H.↗

Scatter of X-rays on polished surfaces

In investigating the dispersion properties of telescope mirrors used in X-ray astronomy, the slight scattering characteristics of X-ray radiation by statistically rough surfaces were examined. The mathematics and geometry of scattering theory are described. The measurement test assembly is described and results of measurements on samples of plane mirrors are given. Measurement results are evaluated. The direct beam, the convolution of the direct beam and the scattering halo, curve fitting by the method of least squares, various autocorrelation functions, results of the fitting procedure for small scattering, and deviations in the kernel of the scattering distribution are presented. A procedure for quality testing of mirror systems through diagnosis of rough surfaces is described.

Hasinger, G.↗

Questions of diagnosing and treating Meniere's disease

The possibilities of diagnosis and treatment of Meniere's disease are considered. Attention is given to the use of dehydration tests which are based on glycerol administration or intravenous injection of furosemide. The risks of bilateral sensorineural hearing impairment in prolonged conservative treatment is emphasized. The data of auditory function study before and following endolymphatic sac surgery are presented.

Khechinashvili, S. N.↗

Event Recorder Scans 2,048 Channels

Up to 16 input signals feed each of up to 128 input circuit cards. Single input circuit card contains optical isolators with input-diode lamping, RC filters, Schmitt-trigger input buffers, and 16-to-1 multiplexer. Input circuit cards feed logic, memory, and input/output circuits, which are standard, off-the-shelf devices. Instrument records sequence and time of events and could be useful in monitoring operation of manufacturing machinery and furnishing information useful in diagnosis of machinery malfunctions.

Slusser, K. J.↗

Ion Mass/Velocity/Charge Spectrometer

Ion spectrometer distributes ions two-dimensionally and measures three characteristics of incident-ion beam: (1) mass/charge distribution, (2) ion velocity distribution, and (3) direction of incidence. Also useful for diagnosis in experimental plasma physics in collisionless regime. Ion spectrometer uses novel combination of standard electrostatic and magnetic deflection techniques to sort incident ions according to speed, diretion of incidence, and mass/ charge ratio.

Neugebauer, M. M.↗

Traveling-wave maser, closed cycle refrigerator automation

At the present time all traveling-wave maser and closed-cycle refrigerator system (TWM-CCR) and their power supply and helium compressor assemblies are operated manually. Many man-hours are required of highly trained and experienced operators, resulting in high operator cost. Of greater importance are the problems of unpredictable failure and long downtimes. Since field performance is not monitored, system degradation is detected only when it has progressed to the point of catastrophic failure. Without the aid of performance histories, failure diagnosis is arduous and slow. Rational and functional requirements for the TWM-CCR Automation project are the following: (1) to improve reliability and reduce downtime by providing unattended monitor and control, alarm and fault location, failure prediction and self-corrective action; (2) to reduce operator cost by providing automatic tuning and cooldown procedures; and (3) to improve system operations and development by providing the needed engineering data.

Mcneil, J. A.↗