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At least 577 records · Page 32

Infrared On-Orbit Inspection of Shuttle Orbiter Reinforced Carbon-Carbon Using Solar Heating

Thermographic nondestructive inspection techniques have been shown to provide quantitative, large area damage detection capabilities for the ground inspection of the reinforced carbon-carbon (RCC) used for the wing leading edge of the Shuttle orbiter. The method is non-contacting and able to inspect large areas in a relatively short inspection time. Thermal nondestructive evaluation (NDE) inspections have been shown to be applicable for several applications to the Shuttle in preparation for return to flight, including for inspection of RCC panels during impact testing, and for between-flight orbiter inspections. The focus of this work is to expand the capabilities of the thermal NDE methodology to enable inspection by an astronaut during orbital conditions. The significant limitations of available resources, such as weight and power, and the impact of these limitations on the inspection technique are discussed, as well as the resultant impact on data analysis and processing algorithms. Of particular interest is the impact to the inspection technique resulting from the use of solar energy as a heat source, the effect on the measurements due to working in the vacuum of space, and the effect of changes in boundary conditions, such as radiation losses seen by the material, on the response of the RCC. The resultant effects on detectability limits are discussed. Keywords: Nondestructive Evaluation, Shuttle, on-orbit inspection, thermography, infrared

Howell, P. A.↗

Earth Rotation and Global Change

Global climate change, whether from natural or man-made causes, can be expected to lead to changes in the Earth's rotation. General Circulation Models (GCMs) of the atmosphere that have been used to study the effects of changes in the amount of atmospheric greenhouse gasses general predict the globally averaged temperature to increase by 1 degree to 4 degrees C during the next century. This temperature increase is not expected to occur uniformly over the globe, but should exhibit regional variations. This changing atmospheric temperature field will cause changes in the atmospheric wind field and hence in the atmospheric angular momentum (AAM). Since the angular momentum of the atmosphere-solid Earth system is conserved, a thermally-induced change in the AAM will cause consequent changes in the rotation of the solid Earth...

Dickey, J. O.↗

Climate change, malaria and neglected tropical diseases: a scoping review

Abstract To explore the effects of climate change on malaria and 20 neglected tropical diseases (NTDs), and potential effect amelioration through mitigation and adaptation, we searched for papers published from January 2010 to October 2023. We descriptively synthesised extracted data. We analysed numbers of papers meeting our inclusion criteria by country and national disease burden, healthcare access and quality index (HAQI), as well as by climate vulnerability score. From 42 693 retrieved records, 1543 full-text papers were assessed. Of 511 papers meeting the inclusion criteria, 185 studied malaria, 181 dengue and chikungunya and 53 leishmaniasis; other NTDs were relatively understudied. Mitigation was considered in 174 papers (34%) and adaption strategies in 24 (5%). Amplitude and direction of effects of climate change on malaria and NTDs are likely to vary by disease and location, be non-linear and evolve over time. Available analyses do not allow confident prediction of the overall global impact of climate change on these diseases. For dengue and chikungunya and the group of non-vector-borne NTDs, the literature privileged consideration of current low-burden countries with a high HAQI. No leishmaniasis papers considered outcomes in East Africa. Comprehensive, collaborative and standardised modelling efforts are needed to better understand how climate change will directly and indirectly affect malaria and NTDs.

60 APPLIED LIFE SCIENCES↗

Viscous-flow analysis of a subsonic transport aircraft high-lift system and correlation with flight data

High-lift system aerodynamics has been gaining attention in recent years. In an effort to improve aircraft performance, comprehensive studies of multi-element airfoil systems are being undertaken in wind-tunnel and flight experiments. Recent developments in Computational Fluid Dynamics (CFD) offer a relatively inexpensive alternative for studying complex viscous flows by numerically solving the Navier-Stokes (N-S) equations. Current limitations in computer resources restrict practical high-lift N-S computations to two dimensions, but CFD predictions can yield tremendous insight into flow structure, interactions between airfoil elements, and effects of changes in airfoil geometry or free-stream conditions. These codes are very accurate when compared to strictly 2D data provided by wind-tunnel testing, as will be shown here. Yet, additional challenges must be faced in the analysis of a production aircraft wing section, such as that of the NASA Langley Transport Systems Research Vehicle (TSRV). A primary issue is the sweep theory used to correlate 2D predictions with 3D flight results, accounting for sweep, taper, and finite wing effects. Other computational issues addressed here include the effects of surface roughness of the geometry, cove shape modeling, grid topology, and transition specification. The sensitivity of the flow to changing free-stream conditions is investigated. In addition, the effects of Gurney flaps on the aerodynamic characteristics of the airfoil system are predicted.

Potter, R. C.↗

Landscape Evolution, A Comparison of Form and Process

This project's goals were to collect, analyze and interpret 3-dimensional physiographic data for understanding the processes responsible for landscape modification. The primary landforms to be studied were Neogene cinder cones in Arizona (San Francisco Volcanic Field (SFVF), Coconino and Kaibab National Forests, Arizona). We also obtained and are still analyzing digital topographic data for the Long Valley-White Mountains area of California, which display Quaternary normal fault scarps, as well as extensive evidence of degradation. The work resulted in a large database of measured rates of downslope transport of slope debris. It was hypothesized that the work would increase our understanding of process-response models of hillslope degradation, and of the effects of climate change and other parameters on degradation rates. In greater detail, our primary goal was to compare evolutionary sequences of hillslopes, as exemplified by the topography of landforms of the same type but of different ages, with measurements of the surficial processes active on the landforms. Assuming that other parameters, such as hillslope materials and vegetation are held constant, and that the effects of changing climate are negligible, then the sediment transport rates measured today on the landforms should be the same as those calculated from the inversion of landform topography by use of a diffusion-type model. However, if the effects of changing climate or other factors are not negligible, then the observed transport rates would differ from those which must be invoked to explain the current topography. We hypothesized in fact that because degradation on the event scale is highly transient and localized, we would find a wide divergence between modern, measured transport rates, and rates calculated by global landform inversion or modeling. Because of the length of time involved in collection of sufficient data on current degradation rates, we are still continuing to analyse and interpret the data. Completion of the work will increase our understanding of the potential effects of anthropogenic climate and surficial change on the Earth's solid surface, and possibly allow us to constrain paths of hill-slope evolution following anthropogenic modifications, as well as compare the short-term with the long-term rates of hillslope degradation.

Bursik, Marcus I.↗

Laser with a transmitting window.

The effect of transmission of radiation through one mirror of a laser is investigated. For a laser oscillator the result is to change the effective resonance frequency and Q of the cavity. Using the same model for the cavity, a signal is injected into the active medium through the transmitting window, and its effect on the system studied. When the external signal is strong enough and sufficiently close to the natural frequency of the laser oscillator, the laser locks its frequency to the input signal. The equations describing the system are solved over the range of input frequencies where the laser is locked, and the resulting gain found. In the high-intensity limit the medium saturates, and the gain tends to that of a lossy cavity. As the input intensity vanishes, the gain approaches infinity and the system tends to a laser oscillator.

Spencer, M. B.↗

Analytical study of the cruise performance of a class of remotely piloted, microwave-powered, high-altitude airplane platforms

Each cycle of the flight profile consists of climb while the vehicle is tracked and powered by a microwave beam, followed by gliding flight back to a minimum altitude. Parameter variations were used to define the effects of changes in the characteristics of the airplane aerodynamics, the power transmission systems, the propulsion system, and winds. Results show that wind effects limit the reduction of wing loading and increase the lift coefficient, two effective ways to obtain longer range and endurance for each flight cycle. Calculated climb performance showed strong sensitivity to some power and propulsion parameters. A simplified method of computing gliding endurance was developed.

Morris, C. E. K., Jr.↗

Parametric study of microwave-powered high-altitude airplane platforms designed for linear flight

The performance of a class of remotely piloted, microwave powered, high altitude airplane platforms is studied. The first part of each cycle of the flight profile consists of climb while the vehicle is tracked and powered by a microwave beam; this is followed by gliding flight back to a minimum altitude above a microwave station and initiation of another cycle. Parametric variations were used to define the effects of changes in the characteristics of the airplane aerodynamics, the energy transmission systems, the propulsion system, and winds. Results show that wind effects limit the reduction of wing loading and the increase of lift coefficient, two effective ways to obtain longer range and endurance for each flight cycle. Calculated climb performance showed strong sensitivity to some power and propulsion parameters. A simplified method of computing gliding endurance was developed.

Morris, C. E. K., Jr.↗

A NASA study of the impact of technology on future multimission aircraft

A conceptual aircraft design study was recently completed which compared three supersonic multimission tactical aircraft. The aircraft were evaluated in two technology timeframes and were sized with consistent methods and technology assumptions so that the aircraft could be compared in operational utility or cost analysis trends. The three aircraft are a carrier-based Fighter/Attack aircraft, a land-based Multirole Fighter, and a Short Takeoff/Vertical Landing (STOVL) aircraft. This paper describes the design study ground rules used and the aircraft designed. The aircraft descriptions include weights, dimensions and layout, design mission and maneuver performance, and fallout mission performance. The effect of changing technology and mission requirements on the STOVL aircraft and the impact of aircraft navalization are discussed. Also discussed are the effects on the STOVL aircraft of both Thrust/Weight required in hover and design mission radius.

Samuels, Jeffrey J.↗

Effects of Acoustically Lined Cylindrical Ducts on Instability Waves in Confined Supersonic Jets

The pressure disturbances generated by an instability wave in the shear layer of a supersonic jet are studied for an axisymmetric jet inside a lined cylindrical duct. For the supersonic jet, locally linear stability analysis with duct wall boundary conditions is used to calculate the eigenvalues and the eigenfunctions. These values are used to determine the growth rates and phase velocities of the instability waves and the radial pressure disturbance patterns. The study is confined to the dominant Kelvin-Helmholtz instability mode and to the region just downstream of the nozzle exit where the shear layer is growing but is still small in size compared to the radius of the duct. Numerical results are used to study the effects of changes in the outer flow, growth in the shear layer thickness, wall distance, wall impedance, and frequency. Results indicate that the effects of the duct wall on shear layer growth rates diminish as the outer flow increases. Also, wall reflections cause variations in growth rates depending on wall height and Strouhal number. These variations are due to the phase relationship between the outgoing and the reflected incoming pressure disturbances at the shear layer. The growth rate variations can be reduced and the maximum growth rate minimized by keeping the imaginary part of the impedance negative.

Dahl, Milo D.↗

Are Medications Involved in Vision and Intracranial Pressure Changes Seen in Spaceflight?

Some crewmembers have experienced changes in their vision after long-duration spaceflight on the ISS. These impairments include visual performance decrements, development of cotton-wool spots or choroidal folds, optic-disc edema, optic nerve sheath distention, and/or posterior globe flattening with varying degrees of severity and permanence. These changes are now used to define the visual impairment/intracranial pressure (VIIP) syndrome. It is known that many medications can have side effects that are similar to VIIP symptoms. Some medications raise blood pressure, which can affect intracranial pressure. Many medications that act in the central nervous system can affect intracranial pressures and/or vision. About 40% of the medications in the ISS kit are known to cause side effects involving changes in blood pressure, intracranial pressure and/or vision. For this reason, we have begun an investigation of the potential relationship between ISS medications and their risk of causing or exacerbating VIIP-like symptoms.

Wotring, V. E.↗

Effects of matter density profiles on neutrino oscillations for T2HK and T2HKK

This paper explores the effects of changes in matter density profiles on neutrino oscillation probabilities, and whether these could potentially be seen by the future Hyper-Kamiokande long-baseline oscillation experiment (T2HK). The analysis is extended to include the possibility of having an additional detector in Korea (T2HKK). In both cases, we find that these effects will be immeasurable, as the magnitudes of the changes in the oscillation probabilities induced in all density profile scenarios considered here remain smaller than the estimated experimental sensitivity to the oscillation probabilities of each experiment, for both appearance and disappearance channels. Therefore, we conclude that using a constant density profile is sufficient for both the T2HK and T2HKK experiments.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Plasma GFAP for populational enrichment of clinical trials in preclinical Alzheimer's disease

Abstract INTRODUCTION Cognitively unimpaired (CU) amyloid beta (Aβ)+ individuals with elevated plasma glial fibrillary acidic protein (GFAP) have an increased risk of Alzheimer's disease (AD)‐related progression. We tested the utility of plasma GFAP for population enrichment CU populations in clinical trials. METHODS We estimated longitudinal progression, effect size, and costs of hypothetical clinical trials designed to test an estimated 25% drug effect on reducing tau positron emission tomography (PET) accumulation in the medial temporal lobe (MTL) and temporal neocortical region (NEO‐T). RESULTS CU GFAP+/Aβ+ individuals present an increased annual rate of change and effect size in tau PET MTL and tau PET NEO‐T compared to the other groups. An enrichment strategy selecting CU GFAP+/Aβ+ individuals would require a smaller sample size (≈ 57% reduction) and fewer Aβ PET scans (≈ 74% reduction) than trials enriched with Aβ PET alone, reducing total clinical trial costs by up to 64%. DISCUSSION Our results suggest that clinical trials focusing on preclinical AD recruiting Aβ+ individuals with elevated GFAP levels would improve cost effectiveness. Highlights Cognitively unimpaired (CU) glial fibrillary acidic protein (GFAP)+/amyloid beta (Aβ)+ shows increased changes in tau positron emission tomography (PET) . CU GFAP+/Aβ+ enriched clinical trials require a reduced sample size compared to Aβ+ only. CU GFAP+/Aβ+ enrichment reduces Aβ PET scans required and costs. CU GFAP+/Aβ+ enrichment allows the selection of individuals at early stages of the Alzheimer's disease continuum.

Neurosciences & Neurology↗

The simulated Indian monsoon: A GCM sensitivity study

A series of sensitivity experiments are conducted in an attempt to understand and correct deficiencies in the simulation of the seasonal mean Indian monsoon with a global atmospheric general circulation model. The seasonal mean precipitation is less than half that observed. This poor simulation in seasonal integrations is independent of the choice of initial conditions and global sea surface temperature data used. Experiments are performed to test the sensitivity of the Indian monsoon simulation to changes in orography, vegetation, soil, wetness, and cloudiness. The authors find that the deficiency of the model precipitation simulation may be attributed to the use of an enhanced orography in the integrations. Replacement of this orography with a mean orography results in a much more realistic simulation of Indian monsoon circulation and rainfall. Experiments with a linear primitive equation model on the sphere suggest that this striking improvement is due to modulations of the orographically forced waves in the lower troposphere. This improvement in the monsoon simulation is due to the kinematic and dynamical effects of changing the topography, rather than the thermal effects, which were minimal. The magnitude of the impact on the Indian monsoon of the other sensitivity experiments varied considerably, but was consistently less than the impact of using the mean orography. However, results from the soil moisture sensitivity experiments suggest a possibly important role for soil moisture in simulating tropical precipitation, including that associated with the Indian monsoon.

Fennessy, M. J.↗

Deposition of ultrathick heavy-metal alloys on rotating substrates by high-power impulse magnetron sputtering: Target erosion effects

Sputter deposition of ultrathick (≈20μm) Au–Ta alloy coatings on sphero-cylindrical substrates is key for the fabrication of hohlraums for magnetically assisted inertial confinement fusion. In this work, we study the deposition of AuTa 4 alloy coatings onto rotating substrates. We use high-power impulse magnetron sputtering (HiPIMS) in a constant peak target voltage mode. Results show that the target erosion state has a strong impact on the dominant crystallographic phase, microstructure, surface morphology, and electrical resistivity of AuTa 4 films. This is due to effects of changes in the confining magnetic field with target erosion on the HiPIMS discharge characteristics and the sputter source output. We quantify these effects via plasma diagnostics and discuss the optimization of HiPIMS deposition of ultrathick films for cases when target erosion effects dominate film properties.

36 MATERIALS SCIENCE↗

Dynamic-stability tests on an aircraft escape module at Mach numbers from 0.40 to 2.16

Wind-tunnel measurements of the aerodynamic damping and oscillatory stability of a model of a proposed escape module for a military aircraft have been made using a small-amplitude forced-oscillation technique in pitch and yaw at Mach numbers from 0.40 to 2.16 and in roll at Mach numbers from 0.40 to 1.20. The results in pitch indicate regions in the angle-of-attack range where the model exhibits large and rapid changes in both damping and stability with angle of attack, probably caused by vortex flow over the fins. There was no pronounced effect of change in angle of attack on damping in yaw. Except for the highest Mach number, negative damping in roll was produced at high negative angles of attack.

Davenport, E. E.↗

Alternative jet aircraft fuels

Potential changes in jet aircraft fuel specifications due to shifts in supply and quality of refinery feedstocks are discussed with emphasis on the effects these changes would have on the performance and durability of aircraft engines and fuel systems. Combustion characteristics, fuel thermal stability, and fuel pumpability at low temperature are among the factors considered. Combustor and fuel system technology needs for broad specification fuels are reviewed including prevention of fuel system fouling and fuel system technology for fuels with higher freezing points.

Grobman, J.↗

Experimental performance of the regenerator for the Chrysler upgraded automotive gas turbine engine

Automobile gas turbine engine regenerator performance was studied in a regenerator test facility that provided a satisfactory simulation of the actual engine operating environment but with independent control of airflow and gas flow. Velocity and temperature distributions were measured immediately downstream of both the core high-pressure-side outlet and the core low-pressure-side outlet. For the original engine housing, the regenerator temperature effectiveness was 1 to 2 percent higher than the design value, and the heat transfer effectiveness was 2 to 4 percent lower than the design value over the range of test conditions simulating 50 to 100 percent of gas generator speed. Recalculating the design values to account for seal leakage decreased the design heat transfer effectiveness to values consistent with those measured herein. A baffle installed in the engine housing high-pressure-side inlet provided more uniform velocities out of the regenerator but did not improve the effectiveness. A housing designed to provide more uniform axial flow to the regenerator was also tested. Although temperature uniformity was improved, the effectiveness values were not improved. Neither did 50-percent flow blockage (90 degree segment) applied to the high-pressure-side inlet change the effectiveness significantly.

Winter, J. M.↗