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At least 577 records · Page 32

Comprehensive constraints on a spin-3/2 singlet particle as a dark matter candidate

We consider the proposal that dark matter (DM) is composed of a spin-3/2 Dirac-type particle that is a singlet of the standard model (SM). Its leading effective interactions with ordinary matter involve a pair of their fields and a pair of SM fermions, in the form of products of chiral currents. We make a comprehensive analysis on possible phenomenological effects of the interactions in various experiments and observations. These include collider searches for monojet plus missing transverse energy events, direct detections of DM scattering off nuclei, possible impacts on the gamma rays and antiproton-to-proton flux ratio in cosmic rays, and the observed relic density. The current data already set strong constraints on the effective interactions in a complementary manner. The constraint from collider searches is most effective at a relatively low mass of DM, and the antiproton-to-proton flux ratio offers the best bound for a heavy DM, while the spin-independent direct detection is the best in between. Putting all constraints together, a DM mass less than ∼ 1TeV has been excluded, leaving behind a small window for a heavy DM particle of spin-3/2.

79 ASTRONOMY AND ASTROPHYSICS↗

Revealing W51C as a cosmic ray source using Fermi-LAT data

Supernova remnants (SNRs) are commonly believed to be the primary sources of Galactic cosmic rays. Despite intensive study of the non-thermal emission of many SNRs the identification of the accelerated particle type relies heavily on assumptions of ambient-medium parameters that are only loosely constrained. Compelling evidence of hadronic acceleration can be provided by detecting a strong roll-off in the secondary γ-ray spectrum below the π{sup 0} production threshold energy of about 135 MeV, the so called “pion bump.” Here we use five years of Fermi-Large Area Telescope data to study the spectrum above 60 MeV of the middle-aged SNR W51C. A clear break in the power-law γ-ray spectrum at E{sub break}=290±20 MeV is detected with 9σ significance and we show that this break is most likely associated with the energy production threshold of π{sup 0}mesons. A high-energy break in the γ-ray spectrum at about 2.7 GeV is found with 7.5σ significance. The spectral index at energies beyond this second break is Γ{sub 2}=2.52{sub −0.07}{sup +0.06} and closely matches the spectral index derived by the MAGIC Collaboration above 75 GeV. Therefore our analysis provides strong evidence to explain the γ-ray spectrum of W51C by a single particle population of protons with a momentum spectrum best described by a broken power law with break momentum p{sub break}∼80 GeV/c. W51C is the third middle-aged SNR that displays compelling evidence for cosmic-ray acceleration and thus strengthens the case of SNRs as the main source of Galactic cosmic rays.

79 ASTRONOMY AND ASTROPHYSICS↗

ExMC Ground-Based Space Radiation Analog Pilot Drug Stability Studay: Final Data Review

Uncertainty regarding space radiation effects on medication degradation and potency remains high, though early data suggest that space radiation may affect the potency and quality of some pharmaceuticals. In the absence of empirical spaceflight measurements to characterize this risk area for long-duration planetary missions, high-fidelity ground-based targeted radiation analogs could provide valuable insights. The NASA Human Research Program's (HRP) Exploration Medical Capability (ExMC) Element conducted a pilot study to characterize the chemical stability of four selected medications exposed to rapid switching, mixed-species simulated galactic cosmic radiation (GCR) beams at the NASA Space Radiation Laboratory (NSRL), at Brookhaven National Laboratory (BNL). The research objective was to compare the effects of simulated GCR beam exposures on drug stability to those previously observed following spaceflight.

Vernie R Daniels↗

Explanation of the secondary to primary ratio within the continuous Fermi accelerator model

The secondary to primary ratio in galactic cosmic radiation at relativistic momenta is calculated in a model, where the primaries are continuously accelerated from the thermal galactic background medium by 1st and 2nd order Fermi acceleration. It is shown that the measured decrease with momentum does not exclude that cosmic rays are accelerated in the interstellar medium as a whole. Once a momentum dependence of the mean lifetime and the different spatial source distributions are adequately taken into account, the measured decreasing ratio can be explained.

Lerche, I.↗

Effect of re-acceleration on cosmic ray components

Reacceleration of cosmic rays in interstellar space has been studied in detail in order to examine the behavior of the ratios of secondary to primary nuclei in cosmic radiation. It is found that modest acceleration in a confinement region, where particles escape more freely at high energies, provides a better fit to the observed data. The effect of reacceleration on the spectral shape of proton and helium components of cosmic rays has been studied. The examination of two different models has shown that reacceleration provides a poor fit to the observed proton data.

Stephens, S. A.↗

Cardiovascular Responses to Simulated Spaceflight: Molecular Signatures and Surrogate Outputs to Measure CVD Risk

During extended space missions beyond low Earth orbit, astronauts will encounter prolonged periods of weightlessness and low dose space radiation. Previous studies have shown that exposure to small doses of high LET radiation (< 50 cGy) can lead to both short-term and long-term alterations in heart function, structure and underlying molecular mechanisms. In this study, we aim to identify the molecular signature associated with the cardiovascular response to simulated galactic cosmic radiation (5-ion GCR) alone or in combination with simulated weightlessness at time intervals relevant to mission length and recovery. Additionally, we aim to determine whether sex impacts cardiovascular responses to these spaceflight factors. Our overarching goal is to enhance our understanding of the cardiovascular risks associated with extended space missions and the clinical endpoints they suggest. We hypothesize that exposure to simulated space radiation leads to enduring alterations in the transcriptome, redox signaling and cytokine environment of cardiovascular tissue, some which have known links with reduced cardiovascular performance, aging, and increased risk of cardiovascular disease (CVD). Furthermore, we posit that simulated space radiation exposure in combination with simulated microgravity exacerbates cardiovascular deficits compared to single factor exposure. Female and male C57BL/6J mice, aged 23-24 weeks, were exposed to a single dose of 5, 15, or 50 cGy of 5-ion GCR, or sham-treated (0 cGy). Euthanasia was performed at 14 days and ~4 months post-irradiation. Hearts, aorta and blood plasma were collected shortly thereafter. RNA-sequencing of left ventricles at ~4 months post-GCR exposure revealed sex differences in the heart transcriptome with a few genes showing radiation-dependent changes in expression levels. Notably, some of the differentially expressed genes in 15 and 50 cGy GCR groups are known to play roles in the development of CVD. Analysis of protein levels of a subset of inflammatory cytokines in the heart indicated sex differences but no differences between sham and 50 cGy groups. Results also showed correlations among differentially expressed genes and a subset of inflammatory cytokines, with some correlations altered by GCR exposure. These findings suggest that GCR exposure can modify protein and gene networks linked to inflammation and CVD progression. In the aorta, telomere lengths were comparable across treatment groups sexes. Mitochondrial copy number is a biomarker for mitochondrial function with decreased copy numbers associated with cardiometabolic disease traits. Mitochondrial copy numbers of aorta also showed no sex nor dose differences. In a second study, mice underwent one week of simulated microgravity by hindlimb unloading (HU) and then exposed to a single dose of 15 cGy of 5-ion GCR. HU was conducted for an additional two weeks following GCR exposure. Single factor exposure groups (HU or GCR only) also were included in the study. Euthanasia was then performed and the same tissues were collected. Protein levels of select inflammatory cytokines in the heart showed sex-dependent differences in expression. In the aorta, telomere lengths and mitochondrial copy number also showed sex differences. In summary, our results indicate differences between sexes in biomarkers related to cardiovascular health. Exposure to 5-ion GCR or HU, alone or in combination, did not result in changes in most of the cardiovascular biomarkers that were examined. However, in the heart, simulated space radiation at doses of 15 and 50 cGy led to long-term alterations in the expression levels of a small group of genes known to be associated with the progression of CVD. The long-term transcriptomic changes resulting from exposure to simulated space radiation should be carefully investigated to mitigate adverse cardiovascular events during and after deep space missions. Our results also highlight the importance of sex-specific strategies in monitoring and maintaining cardiovascular health during and after deep space missions.

cardiovascular↗

Preliminary total dose measurements on LDEF

After spending nearly six years in Earth's orbit twenty stacks consisting of radiation detectors and biological objects are now back on Earth. These Free Flyer Biostack experiments are part of the Long Duration Exposure Facility (LDEF). The major objective of the experiments are to investigate the biological effectiveness of single heavy ions of the cosmic radiation in various biological systems and to provide information about the spectral composition of the radiation field and the total dose received in the LDEF orbit. The preliminary analysis of the thermoluminescence dosimeters (TLD) yields maximum absorbed dose rates of 2.24 mGy day(exp -1) behind 0.7 g cm(exp -2) shielding and 1.17 mGy day(exp -1) behind 12 g cm(exp -2) shielding. A thermal neutron fluence of 1.7 n cm(exp -2)s(exp -1) is determined from the differences in absorbed dose for different isotopic mixtures of lithium. The results of this experiment on LDEF are especially valuable since LDEF stayed for almost six years in the prospected orbit of the Space Station Freedom.

Reitz, G.↗

Large-scale anisotropy of the cosmic microwave background radiation

Inhomogeneities in the large-scale distribution of matter inevitably lead to the generation of large-scale anisotropy in the cosmic background radiation. The dipole, quadrupole, and higher order fluctuations expected in an Einstein-de Sitter cosmological model have been computed. The dipole and quadrupole anisotropies are comparable to the measured values, and impose important constraints on the allowable spectrum of large-scale matter density fluctuations. A significant dipole anisotropy is generated by the matter distribution on scales greater than approximately 100 Mpc. The large-scale anisotropy is insensitive to the ionization history of the universe since decoupling, and cannot easily be reconciled with a galaxy formation theory that is based on primordial adiabatic density fluctuations.

Silk, J.↗

Secondary antiproton production in relativistic plasmas

The possibility is investigated that the reported excess low energy antiproton component of the cosmic radiation results from proton-proton (p-p) interactions in relativistic plasmas. Because of both target and projectile motion in such plasmas, the antiproton production threshold in the frame of the plasma is much lower than the threshold of antiproton production in cosmic ray interactions with ambient matter. The spectrum of the resultant antiprotons therefore extends to much lower energy than in the cosmic ray case. The antiproton spectrum is calculated for relativistic thermal plasmas and the spectrum is estimated for relativistic nonthermal plasmas. As possible production sites, matter accreting onto compact objects located in the galaxy is considered. Possible overproduction of gamma rays from associated neutral pion production can be avoided if the site is optically thick to the photons but not to the antiprotons. A possible scenario involves a sufficiently large photon density that the neutral pion gamma rays are absorbed by photon-photon pair production. Escape of the antiprotons to the interstellar medium can be mediated by antineutron production.

Dermer, C. D.↗

Estimating the change in asymptotic direction due to secular changes in the geomagnetic field

The concept of geomagnetic optics, as described by the asymptotic directions of approach, is extremely useful in the analysis of cosmic radiation data. However, when changes in cutoff occur as a result of evolution in the geomagnetic field, there are corresponding changes in the asymptotic cones of acceptance. A method is introduced of estimating the change in the asymptotic direction of approach for vertically incident cosmic ray particles from a reference set of directions at a specific epoch by considering the change in the geomagnetic cutoff.

Flueckiger, E. O.↗

The First Flight of ATIC : Preliminary Results on CNO Nuclei

We present preliminary results on the spectra of CNO nuclei in the cosmic radiation as measured in the first flight of the Advanced Thin Ionization Calorimeter Balloon Experiment (ATIC) which lasted for 16 days, starting in December, 2000 with a launch from McMurdo, Antarctica. ATIC is a multiple, long duration balloon flight,investigation for the study of cosmic ray spectra from below 50 GeV to near 100 TeV total energy, using a fully active Bismuth Germanate (BGO) calorimeter. It is equipped with the first large area mosaic of small fully depleted silicon detector pads capable of charge identification in cosmic rays from H to Fe. As a redundancy check for the charge identification and a coarse particle tracking system, three projective layers of x-y scintillator hodoscopes were employed, above, in the center and below a Carbon interaction'target'.

Fazely, A.↗

The CNO Concentration in Cosmic Ray Spectrum as Measured From The Advanced Thin Ionization Calorimeter Experiment

We present preliminary results on the spectra of CNO nuclei in the cosmic radiation as measured in the first flight of the Advanced Thin Ionization Calorimeter Balloon Experiment (ATIC) which lasted for 16 days, starting in December, 2000 with a launch from McMurdo, Antarctica. ATIC is a multiple, long duration balloon flight, investigation for the study of cosmic ray spectra from below 50 GeV to near 100 TeV total energy, using a fully active Bismuth Germanate (BGO) calorimeter. It is equipped with the first large area mosaic of small fully depleted silicon detector pads capable of charge identification in cosmic rays from H to Fe. As a redundancy check for the charge identification and a coarse particle tracking system, three projective layers of x-y scintillator hodoscopes were employed, above, in the center and below a Carbon interaction "target".

Fazely, A. R.↗

Relative Abundances and Energy Spectra of C, N, and 0 as Measured by the Advanced Thin Ionization Calorimeter Balloon Experiment

We present results on the spectra and the relative abundances of C, N, and 0 nuclei in the cosmic radiation as measured from the Advanced Thin Ionization Calorimeter Balloon Experiment (ATIC) . The ATIC detector has completed two successful balloon flights from McMurdo, Antarctica lasting a total of more than 35 days. ATIC is designed as a multiple, long duration balloon flight, investigation of the cosmic ray spectra from below 50 GeV to near 100 TeV total energy, using a fully active Bismuth Germanate calorimeter. It is equipped with a large area mosaic of silicon detector pixels capable of charge identification from H to Fe. As a redundancy check for the charge identification and a particle tracking system, three projective layers of x-y scintillator hodoscopes were employed, above, in the middle and below a 0.75 nuclear interaction length graphite target.

Fazely, A. R.↗

Visual Risk Assessment of Space Radiation Exposure for Future Space Exploration Missions

Protecting astronauts from space radiation exposure during an interplanetary mission is an important challenge for mission design and operations. If sufficient protection is not provided near solar maximum, the risk can be significant due to exposure to sporadic solar particle events (SPEs) as well as to the continuous galactic cosmic radiation (GCR). Polyethylene shielded "storm shelters" inside spacecraft have been shown to limit total exposure from a large SPE to a permissible level, preventing acute risks and providing a potential approach to fulfill the ALARA (as low as reasonably achievable) requirement. For accurate predictions of radiation dose to astronauts involved in future space exploration missions, detailed variations of radiation shielding properties are required. Radiation fluences and doses vary considerably across both the spacecraft geometry and the body-shielding distribution. A model using a modern CAD tool ProE(TradeMark), which is the leading engineering design platform at NASA, has been developed to account for these local variations in the radiation distribution. Visual assessment of radiation distribution at different points inside a spacecraft module and in the human body for a given radiation environment are described. Results will ultimately guide in developing requirements for maximal protection for astronauts from space radiation.

Hussein, Hesham F.↗

Long-term effects of acute irradiation and isolation on crew age-matched mice

The future of space missions beyond low-Earth orbit presents exciting opportunities but may come with formidable health challenges. Astronauts face a unique combination of space stressors capable of exerting effects on the central nervous system (CNS) with possible sex-dependent differences. The interaction of these combined spaceflight stressors may induce oxidative stress, thereby altering brain integrity and behavioral performance. Understanding these changes is critical for safeguarding astronaut health and enabling successful exploration. By understanding the physiological responses to the combined effects of ionizing radiation (IR) and social isolation in the brain through immunohistochemistry (IHC), proteomics and cytokine expression analyses, we aim to identify CNS pathways ripe for countermeasure development to mitigate adverse brain changes with future deep space exploration. Here, we study the combined effects of simulated 5-ion galactic cosmic radiation (GCRsim) at acute dosage (5, 15, and 50 cGy) and social isolation on crew age-matched male and female mice at 124 days post-irradiation. We conducted analyses of hippocampal cytokine biomarkers and proteomic profiling on hippocampal lysates. Our findings reveal sex-specific regulation of hippocampal cytokines and proteomic profiles. Ongoing immunohistochemistry findings on the hippocampus will provide qualitative information regarding key protein expression and cellular changes such as microglial activation, blood brain barrier integrity, and neuroinflammation. With future plans for long-duration space missions, such as Mars exploration, understanding CNS changes over extended periods in mice can provide insights into potential long-term health impacts on astronauts. This project will provide us with valuable insights into sex-differences in neurobiological processes and disease mechanisms impacting men and women in space.

space radiation↗

BLAZARS AS ULTRA-HIGH-ENERGY COSMIC-RAY SOURCES: IMPLICATIONS FOR TeV GAMMA-RAY OBSERVATIONS

The spectra of BL Lac objects and Fanaroff-Riley I radio galaxies are commonly explained by the one-zone leptonic synchrotron self-Compton (SSC) model. Spectral modeling of correlated multiwavelength data gives the comoving magnetic field strength, the bulk outflow Lorentz factor, and the emission region size. Assuming the validity of the SSC model, the Hillas condition shows that only in rare cases such sources accelerate protons to much above 10{sup 19} eV, so {approx}> 10{sup 20} eV ultra-high-energy cosmic rays (UHECRs) are likely to be heavy ions if powered by this type of radio-loud active galactic nuclei (AGNs). Survival of nuclei is shown to be possible in TeV BL Lacs and misaligned counterparts with weak photohadronic emissions. Another signature of hadronic production is intergalactic UHECR-induced cascade emission, which is an alternative explanation of the TeV spectra of some extreme non-variable blazars such as 1ES 0229+200 or 1ES 1101-232. We study this kind of cascade signal, taking into account effects of the structured extragalactic magnetic fields in which the sources should be embedded. We demonstrate the importance of cosmic-ray deflections on the {gamma}-ray flux, and show that required absolute cosmic-ray luminosities are larger than the average UHECR luminosity inferred from UHECR observations and can even be comparable to the Eddington luminosity of supermassive black holes. Future TeV {gamma}-ray observations using the Cerenkov Telescope Array and the High Altitude Water Cerenkov detector array can test for UHECR acceleration by observing >25 TeV photons from relatively low redshift sources such as 1ES 0229+200, and {approx}>TeV photons from more distant radio-loud AGNs.

79 ASTRONOMY AND ASTROPHYSICS↗

Ultra high energy cosmic rays and possible signature of black strings

Ultra high energy cosmic rays (UHECRs) probably originate in extreme conditions in which extra dimension effects might be important. In this paper we calculate the correction in black hole accretion mechanisms due to extra dimension effects in the static and rotating cases. A parametrization of the external Kerr horizons in both cases is presented and analysed. We use previous calculations of upper limits on the UHECR flux to set limits on the UHECR production efficiency of nine sources. The upper limit on the UHECR luminosity calculation is based on GeV-TeV gamma-ray measurements. The total luminosity due to the accretion mechanism is compared to the upper limit on UHECRs. The dependence of the UHECR production efficiency upper limit on black hole mass is also presented and discussed.

79 ASTRONOMY AND ASTROPHYSICS↗

Radiological Impact of 2020 Operations at the Savannah River Site

This report presents environmental dose assessment methods and the estimated potential doses to the public from 2020 Savannah River Site (SRS) atmospheric and liquid radioactive releases. It also documents potential doses from special-case exposure scenarios, such as the consumption of wildlife and/or goat milk. Unless noted, the generic term “dose,” as used in this report, includes both the committed effective dose (50-year committed dose) from internal deposition of radionuclides and the effective dose attributable to sources external to the body. Using the effective dose allows doses from different types of radiation and to different parts of the body to be expressed on the same basis. Humans, plants, and animals potentially receive radiation doses from natural and man-made occurrences. The average annual “background” dose for all people living in the United States is 625 mrem. This includes an average background dose of 311 mrem from naturally occurring radionuclides (found in our bodies and in the earth) and from cosmic radiation. Man-made sources include medical procedures (300 mrem), consumer products (13 mrem), and industrial and occupational exposures (less than 1 mrem).

54 ENVIRONMENTAL SCIENCES↗