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Effects of Replacing Treadmill Running with Alternative Exercise Countermeasures During Long-Duration Spaceflight on Astronaut Health and Performance

INTRODUCTION Current exercise countermeasures on the International Space Station (ISS) include treadmill running, cycle ergometry, and resistive exercise, which are used to protect crewmember health and performance during long-duration spaceflight. However, exploration vehicles for Artemis missions to the Moon and beyond will have volume and power restrictions, requiring exercise hardware to have a smaller footprint and use fewer resources. Thus, recent efforts have focused on developing exercise devices that provide both aerobic and resistive capabilities on one platform without including a treadmill. The European Enhanced Exploration Exercise Device [E4D] is one such apparatus. It is critical to validate the efficacy of using exploration-focused exercise modalities to preserve muscle strength, aerobic fitness, bone density, and sensorimotor performance. Thus, the aim of this study is to determine the effectiveness of using nominal ISS exercise devices for an entire mission compared to exploration-forward exercise modalities to determine if a treadmill is required to maintain current levels of protection during long-duration missions. METHODS Crewmembers are assigned to one of three groups: 1) Controls (n ≥ 40), who partake in nominal exercise on the ISS, including running on the Treadmill with Vibration Isolation and Stabilization 2 (T2), cycling on the Cycle Ergometer with Vibration Isolation and Stabilization (CEVIS), and strength training on the Advanced Resistive Exercise Device (ARED); 2) Active Group 1, who exercise on the CEVIS and ARED only (n = 8); and 3) Active Group 2, who perform aerobic and resistive exercise on the E4D only (n = 8). For Active Group 1, nominal exercise on T2 will be replaced with corresponding exercise on CEVIS. For Active Group 2, a dedicated exercise prescription will be designed to maximize the capabilities of the E4D to include resistive exercise, cycle ergometry, rowing, and rope pulling. Crewmembers in both Active groups are not permitted to perform treadmill exercise for the entirety of their flight. Health and performance markers, including bone mineral density (dual-energy x-ray absorptiometry [DXA]), body composition (DXA), cardiovascular fitness (cycle VO2peak), muscle strength and endurance (isometric/isokinetic testing, power endurance testing), sensorimotor performance (sit-to-stand, obstacle course), postural control (computerized dynamic posturography), and blood and urine biochemical markers of bone metabolism will be assessed before, during, and after spaceflight. RESULTS Fifteen subjects (4 Active [CEVIS + ARED], 11 Control) have been recruited. Data collection is ongoing. CONCLUSIONS This study will assess the efficacy of using exploration exercise modalities, including removing the treadmill exercise capability or exclusively using the E4D, compared to the nominal ISS exercise regimen across an entire mission on bone, muscle, aerobic, and sensorimotor health and performance. Findings from this study will help provide a recommendation on whether these exploration exercise modalities can sufficiently protect against physiological deconditioning during spaceflight or whether a treadmill may be required to maintain current levels of protection during future exploration class spaceflight missions. Supported by the NASA Human Research Program and NASA Exploration Capabilities

A N Varanoske↗
DOE OSTI2025

Nine Canyon Long-Duration Energy Storage: A Feasibility Study

The Nine Canyon Long Duration Energy Storage (LDES) Feasibility Study explores the technical and economic viability of deploying advanced energy storage technologies at Energy Northwest's (EN) Nine Canyon (9C) Wind Project site in Benton County, Washington. Supported by the Washington State Department of Commerce and the U.S. Department of Energy’s Office of Electricity under its LDES Voucher Program, the study represents a collaborative effort between EN, Pacific Northwest National Laboratory (PNNL), and ARES North America. At the core of this effort is the development of a generalized techno-economic modeling framework and evaluation tool designed to assess the value proposition of LDES projects across a variety of contexts. The modeling tool is technology-agnostic and accommodates user-defined parameters such as rated power, energy duration, round-trip efficiency, capital and operational costs, and dispatch constraints. It also integrates economic inputs, including market prices, energy revenue structures, and financing parameters to evaluate performance through key metrics. The tool provides utilities with a transparent, adaptable platform to support decision-making, investment prioritization, and portfolio planning for various storage technologies. To guide scenario design and interpretation, the study first surveyed the LDES technology landscape, including lithium-ion batteries, flow batteries, non-hydro gravity storage, and thermo-mechanical systems, comparing cost trajectories, technical performance, safety and hazards, materials sourcing and recyclability, and spatial/siting considerations. This literature-grounded review highlights technology trade-offs and reinforces the need to align technology choice with site characteristics, use cases, and project objectives. A companion chapter examines ownership structures (EN ownership, third-party ownership, shared models) and offtake options (energy marketing, capacity/energy PPAs, time-of-use PPAs, block-delivery PPAs, and tolling), where PPAs (power purchase agreements) represent contractual arrangements for buying and selling electricity. The chapter also highlights implications for risk allocation, capital access, operational control, and revenue certainty. The study also evaluates supervisory control and data acquisition (SCADA) and transmission interconnection pathways, options include upgrading the existing SCADA or deploying a dedicated LDES controller, with attention to protection schemes, data telemetry, cybersecurity, and regulatory coordination with BPA. In addition, an ARES-specific geotechnical and hydrology assessment presented in the appendix screens multiple corridors for slope stability, bearing capacity, cut-and-fill magnitude, and stormwater behavior.

25 ENERGY STORAGE↗
DOE OSTI2022

Nuclide inventory characterization of EBR-II MOX fuel test pins

Characterization of 3 mixed oxide (MOX) fuel pins from the Experimental Breeder Reactor II (EBR-II) SPA-2/-2B experiment program was performed in support of the Advanced Reactor Experiments for Sodium Fast Reactor Fuels (ARES) joint project between Idaho National Laboratory (INL) and the Japan Atomic Energy Agency (JAEA). The characterization efforts were performed to enable transient testing in the Transient Reactor Test (TREAT) facility at INL and will include post irradiation examination (PIE) and other analyses. MOX fuel pins UW02009, 02011, and 06024 were historically irradiated from 1989 to 1994 for a total of 822.42 effective full power days (EFPDs) and peak burnup of approximately 14.3 at.% (atomic percent of heavy metal atoms, ∼134.4 GWd/t). They had since been placed in storage until a future use was identified. Characterization of the fission products and activation of each fuel pin was necessary to enable removal from storage and subsequent irradiation testing or PIE activities. The initial fuel pin geometry and composition were established using historical documentation. Irradiation history details were utilized to compute irradiated and decayed fuel pin masses, atomic densities, and activities. A pellet-wise axial neutron flux was also computed to assist in evaluation of the axial distribution of {sup 235}U and {sup 239}Pu, per pellet, within each of the test fuel pins. The results computed herein supported experiment design for advanced high-burnup MOX fuel designs under slow transient overpower (MOXTOP) conditions, which was Phase I of the ARES project. (authors)

21 SPECIFIC NUCLEAR REACTORS AND ASSOCIATED PLANTS↗
NASA NTRS1990

Wind-Tunnel Survey of an Oscillating Flow Field for Application to Model Helicopter Rotor Testing

A survey was conducted of the flow field produced by the Airstream Oscillator System (AOS) in the Langley Transonic Dynamics Tunnel (TDT). The magnitude of a simulated gust field was measured at 15 locations in the plane of a typical model helicopter rotor when tested in the TDT using the Aeroelastic Rotor Experimental System (ARES) model. These measurements were made over a range of tunnel dynamic pressures typical of those used for an ARES test. The data indicate that the gust field produced by the AOS is non-uniform across the tunnel test section, but should be sufficient to excite a model rotor.

Mirick, Paul H.↗
NASA NTRS1994

Thermal studies of Martian channels and valleys using Termoskan data

The Termoskan instrument on board the Phobos '88 spacecraft acquired the highest spatial resolution thermal infrared emission data ever obtained for Mars. Included in the thermal images 2 km/pixel, midday observations of several major channel and valley systems including significant portions of Shalbatana, Ravi, Al-Qahira, and Ma'adim Valles, the channel connecting Valles Marineris with Hydraotes Chaos, and channel material in Eos Chasma. Termoskan also observed small portions of the southern beginnings of Simud, Tiu, and Ares Valles and some channel material in Gangis Chasma. Simultaneous broadband visible reflectance data were obtained for all but Ma'adim Vallis. We find that most of the channels and valleys have higher thermal inertias than their surroundings, consistent with previous thermal studies. We show for the first time that the thermal inertia boundaries closely match flat channel floor boundaries. Also, buttes within channels have inertias similiar to the plains surrounding the channels, suggesting the buttes are remnants of a contiguous plains surface. Lower bounds on typical channel thermal inertias range from 8.4 to 12.5 (10(exp -3) cal cm(exp -2) s(exp -1/2)/K) (352 to 523 in SI units of J m(exp -2) s(exp -1/2)/K). Lower bounds on inertia differences with the surrounding heavily cratered plains range from 1.1 to 3.5 (46 to 147 SI). Atmospheric and geometric effects are not sufficient to cause the observed channel inertia enhancements. We favor nonaeolian explanations of the overall channel inertia enhancements based primarily upon the channel floors' thermal homogeneity and the strong correlation of thermal boundaries with floor boundaries. However, localized, dark regions within some channels are likely aeolian in nature as reported previously. Most channels with increased inertias have fretted morphologies such as flat floors with steep walls. Eastern Ravi and southern Ares Valles, the only major channel sections observed that have obvious catastrophic flood bedforms, do not have enhanced inertias. Therefore, we favor fretting processes over catastrophic flooding for explaining the inertia enhancements. We postulate that the inertia enhancements were caused either by the original fretting process or by a process involving the bonding of fines due to an increased availability of water, either initially or secondarily.

Betts, Bruce H.↗
NASA NTRS2003

Buried and Visible Impact Basin Distribution on Mars: Comparison with Magnetization, Gravity and Crustal Thickness Models

The large population of buried impact basins found in MOLA elevation data on Mars provides compelling evidence for a pre-Noachian crust below the oldest visible Early Noachian surface units, and lowland crust below the younger plains that is Early Noachian in age, older than much of the visible highlands, but not as old as the buried pre-Noachian highlands. The large (D greater than 200 km) buried basins are suggested by Quasi-Circular Depressions (QCDs) that are not apparent in image data, and include features up to 3000 lun diameter in both the lowlands (Utopia) and highlands (a newly found "Ares Basin"). There are about a dozen QCDs larger than 1000 km diameter. We have placed these large features in a relative age sequence based on superimposed smaller QCD. Only the youngest and most obvious of these (Hellas, Argyre, Isidis) lack magnetic anomalies within their main rings. These all have an N(200) cumulative crater density of less than 2.5. Somewhat older lowland-making basins (Utopia, Chryse, Acidalia) with an N(200) age of approximately 3.0, have weak magnetic anomalies, and the oldest, most subdued basins (including Ares) with N(200) greater than 3.5 have many strong magnetic anomalies within their main ring. These older basins likely formed before the main magnetic field died. We have compared our inventory of large QCDs with the distribution of gravity anomalies and with a crustal thickness model which shows many roughly circular areas of thinner crust completely or partly surrounded by narrow regions of thicker crust. These have the structure expected for impact basins, and many of them do correspond to the visible or buried QCDs we previously identified. But there are cases where the crustal thickness feature is offset from the QCD found in topography alone, and there are also several, sometimes large examples of such features which do not coincide with QCDs previously identified. For example, we find several likely buried basins revealed in the crustal thickness data in the Arcadia and Amazonis regions which we did not previously identify, including several features in the 600-1200 km diameter range.

Frey, Herbert↗
NASA NTRS2004

Parametric Study for Increasing On-Station Duration via Unconventional Aircraft Launch Approach

The need for better atmospheric predictions is causing the atmospheric science community to look for new ways to obtain longer, higher-resolution measurements over several diurnal cycles. The high resolution, in-situ measurements required to study many atmospheric phenomena can be achieved by an Autonomous Aerial Observation System (AAOS); however, meeting the long on-station time requirements with an aerial platform poses many challenges. Inspired by the half-scale drop test of the deployable Aerial Regional-scale Environmental Survey (ARES) Mars airplane, a study was conducted at the NASA Langley Research Center to examine the possibility of increasing on-station time by launching an airplane directly at the desired altitude. The ARES Mars airplane concept was used as a baseline for Earth atmospheric flight, and parametric analyses of fundamental configuration elements were performed to study their impact on achieving desired on-station time with this class of airplane. The concept involved lifting the aircraft from the ground to the target altitude by means of an air balloon, thereby unburdening the airplane of ascent requirements. The parameters varied in the study were aircraft wingspan, payload, fuel quantity, and propulsion system. The results show promising trends for further research into aircraft-payload design using this unconventional balloon-based launch approach.

Kuhl, Christopher A.↗
NASA NTRS2004

Bioavailability and Pharmacodynamics of Promethazine in Human Subjects

The acute effects of exposure to microgravity include the development of space motion sickness, which usually requires therapeutic intervention. The current drug of choice, promethazine (PMZ), is available to astronauts in three different dosage forms during space flight; its side effects include nausea, dizziness, sedation and impaired psychomotor performance. This ground-based study is designed to validate flight-suitable methods for pharmacodynamic evaluation of PMZ and to estimate bioavailability and pharmacodynamics of PMZ. Experimental design consists of intramuscular administration of three doses of PMZ (12.5,25 and 50 mg) and placebo in a randomized double blind fashion to human subjects and collecting blood, urine and saliva samples for 72 h. Subjects also complete cognitive performance test batteries, WinSCAT (Windows based Space Cognitive Assessment Test) and ARES (ANAM Readiness Evaluation System). Preliminary results indicate a significant relationship (p=9.88e-05) between circulating PMZ levels and cognitive performance parameters. Time to accurately complete memory tasks increases significantly with concentrations; higher concentrations also increase response time and decrease accuracy of substitution and matching tasks. AUC and half-life estimates for PMZ ranged between 0.12 and 1.7 mg.h/L and 15 and 50 h, respectively. These preliminary results indicate that PMZ may exhibit dose-dependent pharmacokinetics in humans; also, WinSCAT and ARES are sensitive for pharmacodynamic assessment of PMZ, and may be applicable for assessing the pharmacodynamics of other neurocognitive drugs.

Boyd, J. L.↗
NASA NTRS2007

Multispectral Imaging from Mars PATHFINDER

The Imager for Mars Pathfinder (IMP) was a mast-mounted instrument on the Mars Pathfinder lander which landed on Mars Ares Vallis floodplain on July 4, 1997. During the 83 sols of Mars Pathfinders landed operations, the IMP collected over 16,600 images. Multispectral images were collected using twelve narrowband filters at wavelengths between 400 and 1000 nm in the visible and near infrared (VNIR) range. The IMP provided VNIR spectra of the materials surrounding the lander including rocks, bright soils, dark soils, and atmospheric observations. During the primary mission, only a single primary rock spectral class, Gray Rock, was recognized; since then, Black Rock, has been identified. The Black Rock spectra have a stronger absorption at longer wavelengths than do Gray Rock spectra. A number of coated rocks have also been described, the Red and Maroon Rock classes, and perhaps indurated soils in the form of the Pink Rock class. A number of different soil types were also recognized with the primary ones being Bright Red Drift, Dark Soil, Brown Soil, and Disturbed Soil. Examination of spectral parameter plots indicated two trends which were interpreted as representing alteration products formed in at least two different environmental epochs of the Ares Vallis area. Subsequent analysis of the data and comparison with terrestrial analogs have supported the interpretation that the rock coatings provide evidence of earlier martian environments. However, the presence of relatively uncoated examples of the Gray and Black rock classes indicate that relatively unweathered materials can persist on the martian surface.

Ferrand, William H.↗
NASA NTRS2006

Launching to the Moon, Mars, and Beyond

The U.S. Vision for Space Exploration, announced in 2004, calls on NASA to finish constructing the International Space Station, retire the Space Shuttle, and build the new spacecraft needed to return to the Moon and go on the Mars. By exploring space, America continues the tradition of great nations who mastered the Earth, air, and sea, and who then enjoyed the benefits of increased commerce and technological advances. The progress being made today is part of the next chapter in America's history of leadership in space. In order to reach the Moon and Mars within the planned timeline and also within the allowable budget, NASA is building upon the best of proven space transportation systems. Journeys to the Moon and Mars will require a variety of vehicles, including the Ares I Crew Launch Vehicle, the Ares V Cargo Launch Vehicle, the Orion Crew Exploration Vehicle, and the Lunar Surface Access Module. What America learns in reaching for the Moon will teach astronauts how to prepare for the first human footprints on Mars. While robotic science may reveal information about the nature of hydrogen on the Moon, it will most likely tale a human being with a rock hammer to find the real truth about the presence of water, a precious natural resource that opens many possibilities for explorers. In this way, the combination of astronauts using a variety of tools and machines provides a special synergy that will vastly improve our understanding of Earth's cosmic neighborhood.

Dumbacher, Daniel L.↗
NASA NTRS2007

International Collaboration in Lunar Exploration

The U.S. Vision for Space Exploration commits the United States to return astronauts to the moon by 2020 using the Ares I Crew Launch Vehicle and Ares V Cargo Launch Vehicle. Like the Apollo program of the 1960s and 1970s, this effort will require preliminary reconnaissance in the form of robotic landers and probes. Unlike Apollo, some of the data NASA will rely upon to select landing sites and conduct science will be based on international missions as well, including SMART-1, SELENE, and Lunar Reconnaissance Orbiter (LRO). Opportunities for international cooperation on the moon also lie in developing lunar exploration technologies. The European Space Agency's SMART-1 orbiter (Figure 1) is making the first comprehensive inventory of key chemical elements in the lunar surface. It is also investigating the impact theory of the moon's formation.'

Morris, K. Bruce↗
NASA NTRS2007

Propellant Gauging for Exploration

This paper presents a brief overview of propellant gauging needs and requirements in the context of lunar exploration missions defined by the Exploration Systems Architecture Study (ESAS) report. A timeline for the development and testing of gauging technologies, and a few key design review dates are presented. A lunar exploration mission scenario is discussed which aids in defining the propellant gauging needs. The fleet of new exploration vehicles includes the Ares I and Ares V launch vehicles, Earth Departure Stage (EDS), Lunar Surface Access Module (LSAM) ascent and descent stages, and the Orion Crew Exploration Vehicle (CEV). The liquid propellant choices are currently oxygen - hydrogen for the launch vehicles, the EDS, and LSAM descent module; oxygen - methane for LSAM ascent module; and monomethylhydrazine nitrogen tetroxide (MMH-NTO) for the CEV. Estimated tank sizes, temperatures, pressures, and storage durations are presented. A baseline propellant gauging system is proposed that is based on high Technology Readiness Level (TRL) gauging technologies. In order to be considered for use on the new exploration vehicles, any new gauging technologies will have to show a clear benefit over the baseline methods in terms of performance and/or cost.

Zimmerli, Gregory A.↗
NASA NTRS2007

Orion GN and C Overview and Architecture

The Crew Exploration Vehicle, named Orion, is a critical element in the Constellation Program to develop the transportation system needed to send humans back to the moon and then beyond. Lockheed Martin is the prime contractor for the Orion spacecraft, which is managed by the Johnson Space Center. The Orion GN&C sub-system is being jointly developed by NASA and Lockheed Martin through a mode team approach. The GN&C is a critical element of the Orion mission to carry astronauts to low earth orbit to service the International Space Station and then on later flights to transfer and return a crew of four to the moon. The Orion GN&C system must perform monitoring and abort functions during ascent, rendezvous and docking in both low earth and lunar orbits, perform uncrewed lunar loiter operations, perform trans earth injection and atmospheric entry and landing. The Orion also must be integrated with the Ares I Crew Launch Vehicle, the Earth Departure Stage of the Ares V and the Lunar Surface Access Module. This paper provides an overview of the Orion GN&C system. The functional capabilities of the Orion GN&C will be provided in the context of Constellation architecture, the key GN&C requirements will be summarized, the GN&C architecture will be presented, the development schedule and plans will summarized and finally conclusions will be presented.

Hu, Howard↗
NASA NTRS2007

A Hardware-in-the-Loop Simulator for Software Development for a Mars Airplane

Draper Laboratory recently developed a Hardware-In-The-Loop Simulator (HILSIM) to provide a simulation of the Aerial Regional-scale Environmental Survey (ARES) airplane executing a mission in the Martian environment. The HILSIM was used to support risk mitigation activities under the Planetary Airplane Risk Reduction (PARR) program. PARR supported NASA Langley Research Center's (LaRC) ARES proposal efforts for the Mars Scout 2011 opportunity. The HILSIM software was a successful integration of two simulation frameworks, Draper's CSIM and NASA LaRC's Langley Standard Real-Time Simulation in C++ (LaSRS++).

Slagowski, Stefan E.↗
NASA NTRS2007

Design for Reliability and Safety Approach for the New NASA Launch Vehicle

The United States National Aeronautics and Space Administration (NASA) is in the midst of a space exploration program intended for sending crew and cargo to the international Space Station (ISS), to the moon, and beyond. This program is called Constellation. As part of the Constellation program, NASA is developing new launch vehicles aimed at significantly increase safety and reliability, reduce the cost of accessing space, and provide a growth path for manned space exploration. Achieving these goals requires a rigorous process that addresses reliability, safety, and cost upfront and throughout all the phases of the life cycle of the program. This paper discusses the "Design for Reliability and Safety" approach for the NASA new launch vehicles, the ARES I and ARES V. Specifically, the paper addresses the use of an integrated probabilistic functional analysis to support the design analysis cycle and a probabilistic risk assessment (PRA) to support the preliminary design and beyond.

Safie, Fayssal M.↗
NASA NTRS2007

Launching to the Moon, Mars, and Beyond

This presentation presents the goals of the Vision for Space Exploration. It gives a general overview of the Ares I and Ares V launch vehicles and shows how they enable NASA's lunar exploration missions. It explains how space exploration can inspire the next generation of explorers.

Kynard, Michael H.↗
NASA NTRS2008

Petrography and Origin of the Unique Achondrite GRA 06128 and 06129: Preliminary Results

GRA 06128 & 06129 are paired achondrites [1], with unique mineral proportions (75% oligoclase), mineral compositions, and oxygen isotope ratios. They appear to represent alkalic igneous rock from a hitherto unsampled differentiated parent body, modified significantly by thermal and shock metamorphism. Samples and Methods: Bulk samples were examined at JSC during splitting for consortium analyses. Microscope and BSE images here are on thick section GRA06128,40. Chemical analyses of minerals were acquired at Johnson Space Center with the Cameca SX100, operated at 15 kV. Feldspar was analyzed with a defocused 5 micron beam @ 5 nA; other minerals were analyzed with a focused beam @ 20 nA. Moessbauer spectra were obtained at ARES, JSC [2]. Intrinsic radioactivity was measured in the low-level counting facility at ARES JSC [3]. An estimated abundance of Al-26 of approx. 70 dpm/kg is within the range determined for eucrites.

Treiman, A. H.↗
NASA NTRS2008

Test and Verification Approach for the NASA Constellation Program

This viewgraph presentation is a test and verification approach for the NASA Constellation Program. The contents include: 1) The Vision for Space Exploration: Foundations for Exploration; 2) Constellation Program Fleet of Vehicles; 3) Exploration Roadmap; 4) Constellation Vehicle Approximate Size Comparison; 5) Ares I Elements; 6) Orion Elements; 7) Ares V Elements; 8) Lunar Lander; 9) Map of Constellation content across NASA; 10) CxP T&V Implementation; 11) Challenges in CxP T&V Program; 12) T&V Strategic Emphasis and Key Tenets; 13) CxP T&V Mission & Vision; 14) Constellation Program Organization; 15) Test and Evaluation Organization; 16) CxP Requirements Flowdown; 17) CxP Model Based Systems Engineering Approach; 18) CxP Verification Planning Documents; 19) Environmental Testing; 20) Scope of CxP Verification; 21) CxP Verification - General Process Flow; 22) Avionics and Software Integrated Testing Approach; 23) A-3 Test Stand; 24) Space Power Facility; 25) MEIT and FEIT; 26) Flight Element Integrated Test (FEIT); 27) Multi-Element Integrated Testing (MEIT); 28) Flight Test Driving Principles; and 29) Constellation s Integrated Flight Test Strategy Low Earth Orbit Servicing Capability.

Strong, Edward↗