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At least 559 records · Page 31

A Biodosimeter for Multiparametric Determination of Radiation Dose, Radiation Quality, and Radiation Risk

Predicting risk of human cancer following exposure of an individual or a population to ionizing radiation is challenging. To an approximation, this is because uncertainties of uniform absorption of dose and the uniform processing of dose-related damage at the cellular level within a complex set of biological variables degrade the confidence of predicting the delayed expression of cancer as a relatively rare event. Cellular biodosimeters that simultaneously report: 1) the quantity of absorbed dose after exposure to ionizing radiation, 2) the quality of radiation delivering that dose, and 3) the risk of developing cancer by the cells absorbing that dose would therefore be useful. An approach to such a multiparametric biodosimeter will be reported. This is the demonstration of a dose responsive field effect of enhanced expression of keratin 18 (K18) in cultures of human mammary epithelial cells irradiated with cesium-1 37 gamma-rays. Dose response of enhanced K18 expression was experimentally extended over a range of 30 to 90 cGy for cells evaluated at mid-log phase. K18 has been reported to be a marker for tumor staging and for apoptosis, and thereby serves as an example of a potential marker for cancer risk, where the reality of such predictive value would require additional experimental development. Since observed radiogenic increase in expression of K18 is a field effect, ie., chronically present in all cells of the irradiated population, it may be hypothesized that K18 expression in specific cells absorbing particulate irradiation, such as the high-LET-producing atomic nuclei of space radiation, will report on both the single-cell distributions of those particles amongst cells within the exposed population, and that the relatively high dose per cell delivered by densely ionizing tracks of those intersecting particles will lead to cell-specific high-expression levels of K18, thereby providing analytical end points that may be used to resolve both the quantity and the quality of the radiation dose absorbed by individual cells. The principal value of this reported potential multiparametric cellular biodosimeter is suggested to be that it justifies a search for similar but more robust radiogenic assays. That is, K18 is only one radiation dose-sensitive expressed protein, whereas analytical techniques of genomics and proteomics can be used to simultaneously analyze multiple gene and protein expressions resulting from radiation-dose absorption. The potential usefulness of multiparametric cellular biodosimeters will be best realized from quantitatively profiling these multiple markers using these modern techniques.

Richmond, Robert↗

Effects of duration and other noise characteristics on the annoyance caused by aircraft-flyover noise

A laboratory experiment was conducted to determine the effects of duration and other noise characteristics on the annoyance caused by aircraft-flyover noise. Duration, doppler shift, and spectra were individually controlled by specifying aircraft operational factors, such as velocity, altitude, and spectrum, in a computer synthesis of the aircraft-noise stimuli. This control allowed the separation of the effects of duration from the other main factors in the experimental design: velocity, tonal content, and sound pressure level. The annoyance of a set of noise stimuli which were comprised of factorial combinations of a 3 durations, 3 velocities, 3 sound pressure levels, and 2 tone conditions were judged. The judgements were made by using a graphical scale procedure similar to numerical category scaling. Each of the main factors except velocity was found to affect the judged annoyance significantly. The interaction of tonal content with sound pressure level was also found to be significant. The duration correction used in the effective-perceived-noise-level procedure, 3 dB per doubling of effective duration, was found to account most accurately for the effect of duration. No significant effect doppler shift was found.

Mccurdy, D. A.↗

BERT-Based Topic Modeling and Information Retrieval to Support Fishbone Diagramming for Safe Integration of Unmanned Aircraft Systems in Wildfire Response

Recent concepts for emerging wildfire response operations have included unmanned aircraft systems (UAS) due to their increasing accessibility and capabilities. To integrate UAS into wildfire response safely, researchers have studied the use of large repositories of historic incident reports to improve the scope of root cause analysis. Recent work has emphasized applying state-of-the-art natural language processing techniques to extract useful information from these repositories. However, it has not yet been studied how these results can be interpreted and integrated into the systems engineering process. In this work, we propose a process in which Bidirectional Encoder Representations from Transformers (BERT)-based topic modeling and information retrieval are applied to a relevant set of documents in order to support the development of a fishbone diagram in a semiautomated process. High-level themes in the document set are identified using topic modeling, which are then refined and interpreted by a human analyst. Then, the themes are used to guide a finer search using information retrieval, which returns specific incident reports of relevance. This provides traceability to specific incidents as well as broader categorizations that comprise the fishbone branches. We apply the proposed process to relevant documents from NASA’s Aviation Safety Reporting System (ASRS). The proposed process is widely applicable when relevant documents are available, and the results from this study will be useful to identifying potential causes of wildfire response UAS incidents.

Hazard analysis↗

BERT-based Topic Modeling and Information Retrieval to Support Fishbone Diagramming for Safe Integration of Unmanned Aircraft Systems in Wildfire Response

Recent concepts for emerging wildfire response operations have included unmanned aircraft systems (UAS) due to their increasing accessibility and capabilities. To integrate UAS into wildfire response safely, researchers have studied the use of large repositories of historic incident reports to improve the scope of root cause analysis. Recent work has emphasized applying state-of-the-art natural language processing techniques to extract useful information from these repositories. However, it has not yet been studied how these results can be interpreted and integrated into the systems engineering process. In this work, we propose a process in which Bidirectional Encoder Representations from Transformers (BERT)-based topic modeling and information retrieval are applied to a relevant set of documents in order to support the development of a fishbone diagram in a semiautomated process. High-level themes in the document set are identified using topic modeling, which are then refined and interpreted by a human analyst. Then, the themes are used to guide a finer search using information retrieval, which returns specific incident reports of relevance. This provides traceability to specific incidents as well as broader categorizations that comprise the fishbone branches. We apply the proposed process to relevant documents from NASA’s Aviation Safety Reporting System (ASRS). The proposed process is widely applicable when relevant documents are available, and the results from this study will be useful to identifying potential causes of wildfire response UAS incidents.

hazard analysis↗

BERT-based Topic Modeling and Information Retrieval to Support Fishbone Diagramming for Safe Integration of Unmanned Aircraft Systems in Wildfire Response

Recent concepts for emerging wildfire response operations have included unmanned aircraft systems (UAS) due to their increasing accessibility and capabilities. To integrate UAS into wildfire response safely, researchers have studied the use of large repositories of historic incident reports to improve the scope of root cause analysis. Recent work has emphasized applying state-of-the-art natural language processing techniques to extract useful information from these repositories. However, it has not yet been studied how these results can be interpreted and integrated into the systems engineering process. In this work, we propose a process in which Bidirectional Encoder Representations from Transformers (BERT)-based topic modeling and information retrieval are applied to a relevant set of documents in order to support the development of a fishbone diagram in a semiautomated process. High-level themes in the document set are identified using topic modeling, which are then refined and interpreted by a human analyst. Then, the themes are used to guide a finer search using information retrieval, which returns specific incident reports of relevance. This provides traceability to specific incidents as well as broader categorizations that comprise the fishbone branches. We apply the proposed process to relevant documents from NASA’s Aviation Safety Reporting System (ASRS). The proposed process is widely applicable when relevant documents are available, and the results from this study will be useful to identifying potential causes of wildfire response UAS incidents.

hazard analysis↗

Integration of SAR and DEM data: Geometrical considerations

General principles for integrating data from different sources are derived from the experience of registration of SAR images with digital elevation models (DEM) data. The integration consists of establishing geometrical relations between the data sets that allow us to accumulate information from both data sets for any given object point (e.g., elevation, slope, backscatter of ground cover, etc.). Since the geometries of the two data are completely different they cannot be compared on a pixel by pixel basis. The presented approach detects instances of higher level features in both data sets independently and performs the matching at the high level. Besides the efficiency of this general strategy it further allows the integration of additional knowledge sources: world knowledge and sensor characteristics are also useful sources of information. The SAR features layover and shadow can be detected easily in SAR images. An analytical method to find such regions also in a DEM needs in addition the parameters of the flight path of the SAR sensor and the range projection model. The generation of the SAR layover and shadow maps is summarized and new extensions to this method are proposed.

Kropatsch, Walter G.↗

Studies of new Higgs boson interactions through nonresonant $HH$ production in the $ b\overline{b}\gamma \gamma $ final state in $pp$ collisions at $ \sqrt{s} $ = 13 TeV with the ATLAS detector

A search for nonresonant Higgs boson pair production in the $ b\overline{b}\gamma \gamma $ final state is performed using 140 fb –1 of proton-proton collisions at a centre-of-mass energy of 13 TeV recorded by the ATLAS detector at the CERN Large Hadron Collider. This analysis supersedes and expands upon the previous nonresonant ATLAS results in this final state based on the same data sample. The analysis strategy is optimised to probe anomalous values not only of the Higgs (H) boson self-coupling modifier κλ but also of the quartic HHVV (V = W, Z) coupling modifier κ 2V . No significant excess above the expected background from Standard Model processes is observed. An observed upper limit μHH < 4.0 is set at 95% confidence level on the Higgs boson pair production cross-section normalised to its Standard Model prediction. The 95% confidence intervals for the coupling modifiers are –1.4 < κ λ < 6.9 and –0.5 < κ 2V < 2.7, assuming all other Higgs boson couplings except the one under study are fixed to the Standard Model predictions. The results are interpreted in the Standard Model effective field theory and Higgs effective field theory frameworks in terms of constraints on the couplings of anomalous Higgs boson (self-)interactions.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Search for boosted low-mass resonances decaying into hadrons produced in association with a photon in pp collisions at $ \sqrt{s}$ = 13 TeV with the ATLAS detector

Many extensions of the Standard Model, including those with dark matter particles, propose new mediator particles that decay into hadrons. This paper presents a search for such low mass narrow resonances decaying into hadrons using 140 fb −1 of proton-proton collision data recorded with the ATLAS detector at a centre-of-mass energy of 13 TeV. The resonances are searched for in the invariant mass spectrum of large-radius jets with two-pronged substructure that are recoiling against an energetic photon from initial state radiation, which is used as a trigger to circumvent limitations on the maximum data recording rate. This technique enables the search for boosted hadronically decaying resonances in the mass range 20–100 GeV hitherto unprobed by the ATLAS Collaboration. The observed data are found to agree with Standard Model predictions and 95% confidence level upper limits are set on the coupling of a hypothetical new spin-1 Z′ resonance with Standard Model quarks as a function of the assumed Z′-boson mass in the range between 20 and 200 GeV.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Search for resonant production of dark quarks in the dijet final state with the ATLAS detector

This paper presents a search for a new Z' resonance decaying into a pair of dark quarks which hadronise into dark hadrons before promptly decaying back as Standard Model particles. This analysis is based on proton-proton collision data recorded at $\sqrt{s}$ = 13 TeV with the ATLAS detector at the Large Hadron Collider between 2015 and 2018, corresponding to an integrated luminosity of 139 fb –1 . After selecting events containing large-radius jets with high track multiplicity, the invariant mass distribution of the two highest-transverse-momentum jets is scanned to look for an excess above a data-driven estimate of the Standard Model multijet background. No significant excess of events is observed and the results are thus used to set 95% confidence-level upper limits on the production cross-section times branching ratio of the Z' to dark quarks as a function of the Z' mass for various dark-quark scenarios.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Test of lepton flavor universality and search for lepton flavor violation in B → Kℓℓ decays

We present measurements of the branching fractions for the decays B → Kμ + μ - and B → Ke + e - , and their ratio (R K ), using a data sample of 711 fb -1 that contains 772 × 10 6 B$\bar{B}$ events. The data were collected at the Υ(4S) resonance with the Belle detector at the KEKB asymmetric-energy e + e - collider. The ratio R K is measured in five bins of dilepton invariant-mass-squared (q 2 ): q 2 $\epsilon$ (0.1, 4.0), (4.00, 8.12), (1.0, 6.0), (10.2, 12.8) and (> 14.18) GeV 2 /c 4 , along with the whole q 2 region. The R K value for q 2 $\epsilon$ (1.0, 6.0) GeV 2 /c 4 is 1.03$^{+0.28}_{-0.24}$ ± 0.01. The first and second uncertainties listed are statistical and systematic, respectively. All results for RK are consistent with Standard Model predictions. We also measure CP-averaged isospin asymmetries in the same q 2 bins. The results are consistent with a null asymmetry, with the largest difference of 2.6 standard deviations occurring for the q 2 $\epsilon$ (1.0, 6.0) GeV 2 /c 4 bin in the mode with muon final states. The measured differential branching fractions, dB/dq 2 , are consistent with theoretical predictions for charged B decays, while the corresponding values are below the expectations for neutral B decays. We have also searched for lepton-flavor-violating B → Kμ ± e ∓ decays and set 90% confidence-level upper limits on the branching fraction in the range of 10 -8 for B + → K + μ ± e ∓ , and B 0 → K 0 μ ± e ∓ modes.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

Search for heavy resonances and quantum black holes in eμ, eτ, and μτ final states in proton-proton collisions at $\sqrt{s}$ = 13 TeV

A search is reported for heavy resonances and quantum black holes decaying into eμ, eτ, and μτ final states in proton-proton collision data recorded by the CMS experiment at the CERN LHC during 2016–2018 at $\sqrt{s}$ = 13 TeV, corresponding to an integrated luminosity of 138 fb -1 . The eμ, eτ, and μτ invariant mass spectra are reconstructed, and no evidence is found for physics beyond the standard model. Upper limits are set at 95% confidence level on the product of the cross section and branching fraction for lepton flavor violating signals. Three benchmark signals are studied: resonant τ sneutrino production in R parity violating supersymmetric models, heavy Z' gauge bosons with lepton flavor violating decays, and nonresonant quantum black hole production in models with extra spatial dimensions. Resonant τ sneutrinos are excluded for masses up to 4.2TeV in the eμ channel, 3.7TeV in the eτ channel, and 3.6TeV in the μτ channel. A Z' boson with lepton flavor violating couplings is excluded up to a mass of 5.0TeV in the eμ channel, up to 4.3Te V in the eτ channel, and up to 4.1TeV in the μτ channel. Quantum black holes in the benchmark model are excluded up to the threshold mass of 5.6TeV in the eμ channel, 5.2TeV in the eτ channel, and 5.0TeV in the μτ channel. In addition, model-independent limits are extracted to allow comparisons with other models for the same final states and similar event selection requirements. The results of these searches provide the most stringent limits available from collider experiments for heavy particles that undergo lepton flavor violating decays.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Search for vector-like leptons coupling to first- and second-generation Standard Model leptons in pp collisions at s = 13 TeV with the ATLAS detector

A search for pair production of vector-like leptons coupling to first- and second-generation Standard Model leptons is presented. The search is based on a dataset of proton-proton collisions at s$$ \sqrt{s} $$ = 13 TeV recorded with the ATLAS detector during Run 2 of the Large Hadron Collider, corresponding to an integrated luminosity of 140 fb−1. Events are categorised depending on the flavour and multiplicity of leptons (electrons or muons), as well as on the scores of a deep neural network targeting particular signal topologies according to the decay modes of the vector-like leptons. In each of the signal regions, the scalar sum of the transverse momentum of the leptons and the missing transverse momentum is analysed. The main background processes are estimated using dedicated control regions in a simultaneous fit with the signal regions to data. No significant excess above the Standard Model background expectation is observed and limits are set at 95% confidence level on the production cross-sections of vector-like electrons and muons as a function of the vector-like lepton mass, separately for SU(2) doublet and singlet scenarios. The resulting mass lower limits are 1220 GeV (1270 GeV) and 320 GeV (400 GeV) for vector-like electrons (muons) in the doublet and singlet scenarios, respectively.

Aad, G↗

Search for charged-lepton flavor violation in top quark production and decay in pp collisions at $ \sqrt{s} $ = 13 TeV

Results are presented from a search for charged-lepton flavor violating (CLFV) interactions in top quark production and decay in pp collisions at a center-of-mass energy of 13 TeV. The events are required to contain one oppositely charged electron-muon pair in the final state, along with at least one jet identified as originating from a bottom quark. The data correspond to an integrated luminosity of 138 fb$^{-1}$, collected by the CMS experiment at the LHC. This analysis includes both the production (q → eμt) and decay (t → eμq) modes of the top quark through CLFV interactions, with q referring to a u or c quark. These interactions are parametrized using an effective field theory approach. With no significant excess over the standard model expectation, the results are interpreted in terms of vector-, scalar-, and tensor-like CLFV four-fermion effective interactions. Finally, observed exclusion limits are set at 95% confidence levels on the respective branching fractions of a top quark to an eμ pair and an up (charm) quark of 0.13 × 10$^{-6}$ (1.31 × 10$^{-6}$), 0.07 × 10$^{-6}$ (0.89 × 10$^{-6}$), and 0.25 × 10$^{-6}$ (2.59 × 10$^{-6}$) for vector, scalar, and tensor CLFV interactions, respectively.[graphic not available: see fulltext]

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Search for lepton-flavor-violating τ decays into a lepton and a vector meson using the full Belle data sample

Charged-lepton-flavor-violation is predicted in several new physics scenarios. We update the analysis of τ lepton decays into a light charged lepton (ℓ = e ± or μ ± ) and a vector meson (V 0 = ρ 0 , Φ, ω, K *0 , or $\overline{K}$ *0 ) using 980 fb -1 of data collected with the Belle detector at the KEKB collider. No significant excess of such signal events is observed, and thus 90% credibility level upper limits are set on the τ → ℓV 0 branching fractions in the range of (1.7–4.3) × 10 -8 . These limits are improved by 30% on average from the previous results.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Search for central exclusive production of top quark pairs in proton-proton collisions at $\sqrt{s}$ = 13 TeV with tagged protons

A search for the central exclusive production of top quark-antiquark pairs ($t\overline{t}$) is performed for the first time using proton-tagged events in proton-proton collisions at the LHC at a centre-of-mass energy of 13 TeV. The data correspond to an integrated luminosity of 29.4 fb -1 . The $t\overline{t}$ decay products are reconstructed using the central CMS detector, while forward protons are measured in the CMS-TOTEM precision proton spectrometer. An observed (expected) upper bound on the production cross section of 0.59 (1.14) pb is set at 95% confdence level, for collisions of protons with fractional momentum losses between 2 and 20%.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Search for resonant and non-resonant Higgs boson pair production in the $b\overline{b}{\tau}^{+}{\tau}^{-}$ decay channel using 13 TeV $pp$ collision data from the ATLAS detector

A search for Higgs boson pair production in events with two $b$-jets and two $τ$-leptons is presented, using a proton–proton collision dataset with an integrated luminosity of 139 fb -1 collected at $\sqrt{s}$ = 13 TeV by the ATLAS experiment at the LHC. Higgs boson pairs produced non-resonantly or in the decay of a narrow scalar resonance in the mass range from 251 to 1600 GeV are targeted. Events in which at least one $τ$-lepton decays hadronically are considered, and multivariate discriminants are used to reject the backgrounds. No significant excess of events above the expected background is observed in the non-resonant search. The largest excess in the resonant search is observed at a resonance mass of 1 TeV, with a local (global) significance of 3.1$σ$ (2.0$σ$). Observed (expected) 95% confidence-level upper limits are set on the non-resonant Higgs boson pair-production cross-section at 4.7 (3.9) times the Standard Model prediction, assuming Standard Model kinematics, and on the resonant Higgs boson pair-production cross-section at between 21 and 900 fb (12 and 840 fb), depending on the mass of the narrow scalar resonance.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Search for vector-like leptons with long-lived particle decays in the CMS muon system in proton-proton collisions at $$\sqrt{\text{s}}$$ = 13 TeV

Abstract A first search is presented for vector-like leptons (VLLs) exclusively decaying into a light long-lived pseudoscalar boson and a standard model τ lepton. The pseudoscalar boson is assumed to have a mass below the τ + τ − threshold, so that it decays exclusively into two photons. It is identified using the CMS muon system. The analysis is carried out using a data set of proton-proton collisions at a center-of-mass energy of 13 TeV collected by the CMS experiment in 2016–2018, corresponding to an integrated luminosity of 138 fb −1. Selected events contain at least one pseudoscalar boson decaying electromagnetically in the muon system and at least one hadronically decaying τ lepton. No significant excess of data events is observed compared to the background expectation. Upper limits are set at 95% confidence level on the vector-like lepton production cross section as a function of the VLL mass and the pseudoscalar boson mean proper decay length. The observed and expected exclusion ranges of the VLL mass extend up to 700 and 670 GeV, respectively, depending on the pseudoscalar boson lifetime.

Chekhovsky, V. [Yerevan Physics Institute]↗

Search for vector-like leptons with long-lived particle decays in the CMS muon system in proton-proton collisions at $\sqrt{s}$ = 13 TeV

A first search is presented for vector-like leptons (VLLs) exclusively decaying into a light long-lived pseudoscalar boson and a standard model τ lepton. The pseudoscalar boson is assumed to have a mass below the τ + τ − threshold, so that it decays exclusively into two photons. It is identified using the CMS muon system. The analysis is carried out using a data set of proton-proton collisions at a center-of-mass energy of 13 TeV collected by the CMS experiment in 2016–2018, corresponding to an integrated luminosity of 138 fb −1 . Selected events contain at least one pseudoscalar boson decaying electromagnetically in the muon system and at least one hadronically decaying τ lepton. No significant excess of data events is observed compared to the background expectation. Upper limits are set at 95% confidence level on the vector-like lepton production cross section as a function of the VLL mass and the pseudoscalar boson mean proper decay length. The observed and expected exclusion ranges of the VLL mass extend up to 700 and 670 GeV, respectively, depending on the pseudoscalar boson lifetime.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗