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At least 559 records · Page 31

Effects of Spaceflight on Bone: The Rat as an Animal Model for Human Bone Loss

The loss of weight bearing during spaceflight results in osteopenia in humans. Decrements in bone mineral reach 3-10% after as little as 75-184 days in space. Loss of bone mineral during flight decreases bone strength and increases fracture risk. The mechanisms responsible for, and the factors contributing to, the changes in bone induced by spaceflight are poorly understood. The rat has been widely used as an animal model for human bone loss during spaceflight. Despite its potential usefulness, the results of bone studies performed in the rat in space have been inconsistent. In some flights bone formation is decreased and cancellous bone volume reduced, while in others no significant changes in bone occur. In June of 1996 Drs. T. Wronski, S. Miller and myself participated in a flight experiment (STS 78) to examine the effects of glucocorticoids on bone during weightlessness. Technically the 17 day flight experiment was flawless. The results, however, were surprising. Cancellous bone volume and osteoblast surface in the proximal tibial metaphysis were the same in flight and ground-based control rats. Normal levels of cancellous bone mass and bone formation were also detected in the lumbar vertebrae and femoral neck of flight rats. Furthermore, periosteal bone formation rate was found to be identical in flight and ground-based control rats. Spaceflight had little or no effect on bone metabolism! These results prompted us to carefully review the changes in bone observed in, and the flight conditions of previous spaceflight missions.

Halloran, B.↗

On gravity from SST, geoid from Seasat, and plate age and fracture zones in the Pacific

A composite map produced by combining 90 passes of SST data show good agreement with conventional GEM models. The SEASAT altimeter data were deduced and found to agree with both the SST and GEM fields. The maps are dominated (especially in the east) by a pattern of roughly east-west anomalies with a transverse wavelength of about 2000 km. Comparison with regional bathymetric data shows a remarkedly close correlation with plate age. Most anomalies in the east half of the Pacific could be partly caused by regional differences in plate age. The amplitude of these geoid or gravity anomalies caused by age differences should decrease with absolute plate age, and large anomalies (approximately 3 m) over old, smooth sea floor may indicate a further deeper source within or perhaps below the lithosphere. The possible plume size and ascent velocity necessary to supply deep mantle material to the upper mantle without complete thermal equilibration was considered. A plume emanating from a buoyant layer 100 km thick and 10,000 times less viscous than the surrounding mantle should have a diameter of about 400 km and must ascend at about 10 cm/yr to arrive still anomalously hot in the uppermost mantle.

Marsh, B. D.↗

Damage Instability and Transition From Quasi-Static to Dynamic Fracture

In a typical mechanical test, the loading phase is intended to be a quasi-static process, while the failure and collapse is usually a dynamic event. The structural strength and modes of damage can seldom be predicted without accounting for these two aspects of the response. For a proper prediction, it is therefore essential to use tools and methodologies that are capable of addressing both aspects of responses. In some cases, implicit quasi-static models have been shown to be able to predict the entire response of a structure, including the unstable path that leads to fracture. However, is it acceptable to ignore the effect of inertial forces in the formation of damage? In this presentation we examine aspects of the damage processes that must be simulated for an accurate prediction of structural strength and modes of failure.

Davila, Carlos G.↗

Fracture of cylindrical and spherical shells containing a crack.

Fatigue and fracture of cylindrical and spherical shells containing a through crack and subjected to internal pressure or torsion are considered. The stress intensity factor ratios giving the effect of curvature are obtained as functions of a dimensionless shell parameter. By using the conventional plastic strip model the plastic zone size around the crack tip and the crack opening displacement are calculated. The calculated COD values are shown to be in good agreement with the experimental results. The fracture criterion of critical COD is verified by using the results of the burst tests in titanium and aluminum alloy cryogenic pressure vessels. Modified fatigue crack propagation models taking into account the bending effect in shells are introduced and are applied to the analysis of experimental data obtained from flat plates, and cylindrical shells under axial tension, internal pressure, and torsion. Finally, the paper includes the effect of humidity on the crack growth rate and the effect of load biaxiality on the rupture strength.

Erdogan, F.↗

Myco-Architecture off Planet: Growing Surface Structures at Destination

Our work focused on filling major select key technical knowledge gaps, and technical aspects to be addressed in a Phase II proposal were identified such as the secretion of glues or plastics by the fungi or bacteria to form biocomposites. Specifically, we raised the technical TRL by assessing the growth of in-house mycelial-producing strains on potential food substrates and analyzed the advantages and disadvantages to their use off planet. Growth of the mycelia on sawdust and powdered nutrients including dried, powdered algae, was used as a baseline. We measured growth as a function of temperature, tested the relevant material properties of the mycelia products produced, and measured the mass of input and output volume for production per volume of material. Mycotecture was produced in a bag simulating the proposed mission implementation. Post-production such as heat treatment (as is done with terrestrial mycotecture)was assessed.The material properties of the dried, frozen and baked mycelial outputs included density, strength,thermal insulation and flame retardation. Tensile/compression testing on biocomposite material specimens was performed to obtain three-dimensional elastic constants, as well as to examine deformation and fracture behavior. These mechanical tests were performed on both dormant and activated samples to understand the evolution of the structural material. In addition, experimental data obtained from the mechanical testing was used to build a failure prediction model that accounts for material anisotropy. This aided in future structural design through a quantitative understanding of the mechanical limits of the material. To examine the texture, defects, fracture surfaces of the material, high-resolution microstructural imaging was utilized before and after the mechanical tests. This microstructural analysis informed us about the macro-structural behavior and influenced structural design. Thermal decomposition analysis was also performed tounderstand the thermal limits.

Biocomposites↗

Analysis of a unidirectional, symmetric buffer strip laminate with damage

A method for predicting the fracture behavior of hybrid buffer strip laminates is presented in which the classical shear-lag model is used to represent the shear stress distribution between adjacent fibers. The method is demonstrated by applying it to a notched graphite/epoxy laminate, and the results show clearly the manner in which the most efficient combination of buffer strip properties can be selected in order to arrest the crack. The ultimate failure stress of the laminate is plotted vs the buffer strip width. It is shown that in the case of graphite-epoxy and S-glass epoxy laminates, the optimum buffer strip spacing to width ratio should be about four to one.

Dharani, L. R.↗

Modeling of the flexural behavior of ceramic-matrix composites

This paper examines the effects of matrix cracking and fiber breakage on the flexural behavior of ceramic composite beams. A model has been proposed to represent the damage evolution of the beam, of which the matrix fracture strain is smaller than that of the fibers. Close form solutions of the critical loads for the initiation of matrix cracking and fiber breakage in the tension side of the beam have been found. The effects of thermal residual stresses and fiber/matrix debonding have been taken into account. The initial deviation of the load-deflection curve from linearity is due to matrix cracking, while fiber breakages are responsible for the drop in the load carrying capacity of the beam. The proportional limit as well as the nonlinear behavior of the beam deflection have been identified. The growth of the damaged zone has also been predicted. A three-point bending case is given as a numerical example.

Kuo, Wen-Shyong↗

Effect of Measured Welding Residual Stresses on Crack Growth

Welding residual stresses in thin plate A516-70 steel and 2219-T87 aluminum butt weldments were measured by the strain-gage hole drilling and X-ray diffraction methods. The residual stress data were used to construct 3D strain fields which were modeled as thermally induced strains. These 3D strain fields were then analyzed with the WARP31) FEM fracture analysis code in order to predict their effect on fatigue and on fracture. For analyses of fatigue crack advance and subsequent verification testing, fatigue crack growth increments were simulated by successive saw-cuts and incremental loading to generate, as a function of crack length, effects on crack growth of the interaction between residual stresses and load induced stresses. The specimen experimental response was characterized and compared to the WARM linear elastic and elastic-plastic fracture mechanics analysis predictions. To perform the fracture analysis, the plate material's crack tearing resistance was determined by tests of thin plate M(T) specimens. Fracture analyses of these specimen were performed using WARP31D to determine the critical Crack Tip Opening Angle [CTOA] of each material. These critical CTOA values were used to predict crack tearing and fracture in the weldments. To verify the fracture predictions, weldment M(T) specimen were tested in monotonic loading to fracture while characterizing the fracture process.

Hampton, Roy W.↗

Martian Central Pit Craters

Impact craters containing central pits are rare on the terrestrial planets but common on icy bodies. Mars is the exception among the terrestrial planets, where central pits are seen on crater floors ( floor pits ) as well as on top of central peaks ( summit pits ). Wood et al. [1] proposed that degassing of subsurface volatiles during crater formation produced central pits. Croft [2] argued instead that central pits might form during the impact of volatile-rich comets. Although central pits are seen in impact craters on icy moons such as Ganymede, they do show some significant differences from their martian counterparts: (a) only floor pits are seen on Ganymede, and (b) central pits begin to occur at crater diameters where the peak ring interior morphology begins to appear in terrestrial planet craters [3]. A study of craters containing central pits was conducted by Barlow and Bradley [4] using Viking imagery. They found that 28% of craters displaying an interior morphology on Mars contain central pits. Diameters of craters containing central pits ranged from 16 to 64 km. Barlow and Bradley noted that summit pit craters tended to be smaller than craters containing floor pits. They also noted a correlation of central pit craters with the proposed rings of large impact basins. They argued that basin ring formation fractured the martian crust and allowed subsurface volatiles to concentrate in these locations. They favored the model that degassing of the substrate during crater formation was responsible for central pit formation due to the preferential location of central pit craters along these basin rings.

Hillman, E.↗

Using the Climbing Drum Peel (CDP) Test to Obtain a G(sub IC) value for Core/Facesheet Bonds

A method of measuring the Mode I fracture toughness of core/facesheet bonds in sandwich Structures is desired, particularly with the widespread use of models that need this data as input. This study examined if a critical strain energy release rate, G(sub IC), can be obtained from the climbing drum peel (CDP) test. The CDP test is relatively simple to perform and does not rely on measuring small crack lengths such as required by the double cantilever beam (DCB) test. Simple energy methods were used to calculate G(sub IC) from CDP test data on composite facesheets bonded to a honeycomb core. Facesheet thicknesses from 2 to 5 plies were tested to examine the upper and lower bounds on facesheet thickness requirements. Results from the study suggest that the CDP test, with certain provisions, can be used to find the GIG value of a core/facesheet bond.

Nettles, A. T.↗

New Developments in NASA's Rodent Research Hardware for Conducting Long Duration Biomedical and Basic Research in Space

Animal models, particularly rodents, are the foundation of pre-clinical research to understand human diseases and evaluate new therapeutics, and play a key role in advancing biomedical discoveries both on Earth and in space. The National Research Councils Decadal survey emphasized the importance of expanding NASA's life sciences research to perform long duration, rodent experiments on the International Space Station (ISS) to study effects of the space environment on the musculoskeletal and neurological systems of mice as model organisms of human health and disease, particularly in areas of muscle atrophy, bone loss, and fracture healing. To accomplish this objective, flight hardware, operations, and science capabilities were developed at NASA Ames Research Center (ARC) to enhance science return for both commercial (CASIS) and government-sponsored rodent research. The Rodent Research Project at NASA ARC has pioneered a new research capability on the International Space Station and has progressed toward translating research to the ISS utilizing commercial rockets, collaborating with academia and science industry, while training crewmembers to assist in performing research on orbit. The Rodent Research Habitat provides a living environment for animals on ISS according to standard animal welfare requirements, and daily health checks can be performed using the habitats camera system. Results from these studies contribute to the science community via both the primary investigation and banked samples that are shared in publicly available data repository such as GeneLab. Following each flight, through the Biospecimen Sharing Program (BSP), numerous tissues and thousands of samples will be harvested, and distributed from the Space Life and Physical Sciences (SLPS) to Principal Investigators (PIs) through the Ames Life Science Data Archive (ALSDA). Every completed mission sets a foundation to build and design greater complexity into future research and answer questions about common human diseases. Together, the hardware improvements (enrichment, telemetry sensors, cameras), new capabilities (live animal return), and experience that the Rodent Research team has gained working with principal investigator teams and ISS crew to conduct complex experiments on orbit are expanding capabilities for long duration rodent research on the ISS to achieve both basic science and biomedical research objectives.

Shirazi, Yasaman↗

A simplified approach to strain energy release rate computations for interlaminar fracture of composites

A simple approach for the strain energy release rate computations based on the finite element method and a singular fitting model is presented. The model uses the stress and displacement distributions at the delamination front. The method is applied to a mixed-mode double cracked-lap-shear composite configuration. The strain energy release rate components predicted by the model are compared with the finite element crack-closure method. The effect of the mesh size on the stress and displacement distribution is isolated. The strain energy release rates predicted by relatively coarse mesh sizes are in good agreement with the finite element crack closure method.

Armanios, Erian A.↗

Numerical Analysis Of Interlaminar-Fracture Toughness

Finite-element analysis applied in conjunction with strain-energy and micromechanical concepts. Computational procedure involves local, local-crack-closure, and/or the "unique" local-crack-closure method developed at NASA Lewis Research Center, for mathematical modeling of ENF and MMF. Methods based on three-dimensional finite-element analysis in conjunction with concept of strain-energy-release rate and with micromechanics of composite materials. Assists in interpretation of ENF and MMF fracture tests performed to obtain fracture-toughness parameters, by enabling evaluation of states of stress likely to induce interlaminar fractures.

Chamis, C. C.↗

A material selection method based on material properties and operating parameters

The influence of strength, fracture toughness, and crack growth resistance on the design stress level has been determined from a mathematical model of crack growth and failure. The results show that to select materials properly, the operating parameters of desired life and initial flaw size must be considered simultaneously with the material properties. To do this, a method for constructing an operating surface is derived, discussed, and illustrated.

Elber, W.↗

Fracture and crack growth in orthotropic laminates. Part 2: Experimental determination of internal damage growth in unidirectional boron/aluminum composite laminates

The fracture behavior of unidirectional boron/aluminum composite laminates is investigated in order to verify the results of mathematical models. These models predict the stresses and displacements of fibers and the amount of damage growth in a center-notched lamina as a function of the applied remote stress and the matrix and fiber material properties. The damage may take the form of longitudinal yielding and splitting in the matrix as well as stable transverse damage consisting of broken fibers and matrix yielding ahead of the notch. A brittle lacquer coating is used to detect the yielding in the matrix while X-ray techniques are used to detemine the number of broken fibers in the laminate. The notched strengths and the amounts of damage found in the experimental specimens agree well with those predicted by the mathematical model.

Goree, J. G.↗

Experimental and analytical investigation of the fracture processes of boron/aluminum laminates containing notches

Experimental results for five laminate orientations of boron/aluminum composites containing either circular holes or crack-like slits are presented. Specimen stress-strain behavior, stress at first fiber failure, and ultimate strength were determined. Radiographs were used to monitor the fracture process. The specimens were analyzed with a three-dimensional elastic-elastic finite-element model. The first fiber failures in notched specimens with laminate orientation occurred at or very near the specimen ultimate strength. For notched unidirectional specimens, the first fiber failure occurred at approximately one-half of the specimen ultimate strength. Acoustic emission events correlated with fiber breaks in unidirectional composites, but did not for other laminates. Circular holes and crack-like slits of the same characteristic length were found to produce approximately the same strength reduction. The predicted stress-strain responses and stress at first fiber failure compared very well with test data for laminates containing 0 deg fibers.

Johnson, W. S.↗

Fracture behavior of unidirectional boron/aluminum composite laminates

An experimental investigation of the fracture behavior of unidirectional boron/aluminum composite laminates was conducted in order to verify the results of mathematical models. These models predict the fiber stresses and displacements and the amount of damage growth in a center-notched lamina as a function of the applied remote stress and the matrix and fiber material properties. A brittle lacquer coating was used to detect the yielding in the matrix while X-ray techniques were used to determine the number of broken fibers in the laminate. The notched strengths and the amounts of damage found in the specimens agreed well with those predicted by the models. It was shown that for thin laminates the amount of damage and the fiber displacements do not depend strongly on the number of plies for a given notch width.

Jones, F. W.↗

Gas-driven water volcanism in the resurfacing of Europa

The creation of pathways for resurfacing of water or volatiles in a model of Europa in which an ocean underlies a thin ice shell is subjected to linear elastic fracture mechanical treatment. The gas-filled portion of the upward-propagating cracks pinches off from the water-filled portion, and may rapidly rise to the surface. The eruption thus generated is at first dominated by gas, but may subsequently include a less extended foam eruption; there may be no direct relationship between this resurfacing phenomenon and the geological features thus far noted on the Europa surface.

Crawford, Glen D.↗