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At least 541 records · Page 30

Manufacture of porous biodegradable polymer conduits by an extrusion process for guided tissue regeneration

We have fabricated porous, biodegradable tubular conduits for guided tissue regeneration using a combined solvent casting and extrusion technique. The biodegradable polymers used in this study were poly(DL-lactic-co-glycolic acid) (PLGA) and poly(L-lactic acid) (PLLA). A polymer/salt composite was first prepared by a solvent casting process. After drying, the composite was extruded to form a tubular construct. The salt particles in the construct were then leached out leaving a conduit with an open-pore structure. PLGA was studied as a model polymer to analyze the effects of salt weight fraction, salt particle size, and processing temperature on porosity and pore size of the extruded conduits. The porosity and pore size were found to increase with increasing salt weight fraction. Increasing the salt particle size increased the pore diameter but did not affect the porosity. High extrusion temperatures decreased the pore diameter without altering the porosity. Greater decrease in molecular weight was observed for conduits manufactured at higher temperatures. The mechanical properties of both PLGA and PLLA conduits were tested after degradation in vitro for up to 8 weeks. The modulus and failure strength of PLLA conduits were approximately 10 times higher than those of PLGA conduits. Failure strain was similar for both conduits. After degradation for 8 weeks, the molecular weights of the PLGA and PLLA conduits decreased to 38% and 43% of the initial values, respectively. However, both conduits maintained their shape and did not collapse. The PLGA also remained amorphous throughout the time course, while the crystallinity of PLLA increased from 5.2% to 11.5%. The potential of seeding the conduits with cells for transplantation or with biodegradable polymer microparticles for drug delivery was also tested with dyed microspheres. These porous tubular structures hold great promise for the regeneration of tissues which require tubular scaffolds such as peripheral nerve, long bone, intestine, or blood vessel.

NASA Discipline Cell Biology↗

Whistler Chorus Amplification in the Magnetosphere: The Nonlinear Free‐Electron Laser Model and the Ginzburg‐Landau Equation

We present a novel nonlinear model for whistler-mode chorus amplification based on the free-electron laser (FEL) mechanism. First, we derive the nonlinear collective variable equations for the whistler-electron interaction. Consistent with in situ satellite observations, these equations predict that a small seed wave can undergo exponential growth, reaching a peak of a few hundred picoteslas after a few milliseconds, followed by millisecond timescale amplitude modulations. Next, we show that when one accounts for multiple wave frequencies and wave spatial variations, the amplitude and phase of the whistler wave can be described by the Ginzburg-Landau equation (GLE), providing a framework for the investigation of solitary wave behavior of chorus modes. These findings enhance our understanding of wave-particle interactions and space weather in the Van Allen radiation belts, deepen the connection between whistler-electron dynamics and FELs, and reveal a novel connection between whistler-mode chorus and the GLE.

Ginsburg-Landau equation↗

Simulation of the SPARC plasma boundary with the UEDGE code

Here in this work, the UEDGE edge transport code is used to examine conditions in the SPARC divertor and edge plasma for various levels of carbon impurity and power from the core (P SOL ). A double-null magnetic configuration is simulated assuming up-down symmetry in geometry and physics. The anomalous heat and particle transport coefficients are tuned to match empirical predictions for SPARC's midplane density profiles, target plate heat flux profiles, and inner/outer divertor power sharing. Convective transport is included on the low-field side, while on the high-field side the transport is modeled as purely diffusive. Hydrogen neutrals are modeled as a fluid with inertial effects, and a carbon impurity is included using the fixed-fraction model. We find that detachment induced by impurity seeding could significantly reduce the heat flux to the divertor surfaces in the SPARC tokamak. At P SOL = 28 MW (the value predicted for SPARC's full-power H-mode scenario) cases with both divertor legs detached were obtained with a carbon impurity fraction between 0.3%–1.4%, far below Z eff limits for SPARC. When the plasma in the outer leg is detached, the peak heat flux density perpendicular to the target plate is below 1 MW m -2 , electron and ion temperatures are less than 1.5 eV, and momentum detachment is observed. However, the detachment state is found to be sensitive to the side-wall boundary conditions, the level of neutral pumping, and the target plate tilt. Finally, a broadly similar SOLPS simulation of SPARC is used to assess the appropriateness of the simpler impurity and neutral models used in UEDGE.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

Achievements of actively controlled divertor detachment compatible with sustained high confinement core in DIII-D and EAST

The compatibility of efficient divertor detachment with high-performance core plasma is vital to the development of magnetically controlled fusion energy. The joint research on the EAST and DIII-D tokamaks demonstrates successful integration of divertor detachment with excellent core plasma confinement quality, a milestone towards solving the critical plasma–wall-interaction (PWI) issue and core-edge integration for ITER and future reactors. In EAST, actively controlled partial detachment with T et,div ~ 5 eV around the strike point and H 98 > 1 in different H-mode scenarios including the high β P H-mode scenario have been achieved with ITER-like tungsten divertor, by optimizing the detachment access condition and performing detailed experiments for core-edge integration. For active long-pulse detachment feedback control, a 30 s H-mode operation with detachment-control duration being 25 s has been successfully achieved in EAST. DIII-D has achieved actively controlled fully detached divertor with low plasma electron temperature (T et,div ≤ 5 eV across the entire divertor target) and low particle flux (degree of detachment, DoD > 3), simultaneously with very high core performance (β N ~3, β P > 2 and H 98 ~ 1.5) in the high βP scenario being developed for ITER and future reactors. The high-β P high confinement scenario is characterized by an internal transport barrier (ITB) at large radius and a weak edge transport barrier (ETB, or pedestal), which are synergistically self-organized. Both the high-β P scenario and impurity seeding facilitate divertor detachment. The detachment access leads to the reduction of ETB, which facilitates the development of an even stronger ITB at large radius in the high β P scenario. Thus, this strong large radius ITB enables the core confinement improvement during detachment. In conclusion, these significant joint DIII-D and EAST advances on the compatibility of high confinement core and detached divertor show a great potential for achieving a high-performance core plasma suitable for long-pulse operation of fusion reactors with controllable steady-state PWIs.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

Fast electron transport dynamics and energy deposition in magnetized, imploded cylindrical plasma

Inertial confinement fusion approaches involve the creation of high-energy-density states through compression. High gain scenarios may be enabled by the beneficial heating from fast electrons produced with an intense laser and by energy containment with a high-strength magnetic field. Here, we report experimental measurements from a configuration integrating a magnetized, imploded cylindrical plasma and intense laser-driven electrons as well as multi-stage simulations that show fast electrons transport pathways at different times during the implosion and quantify their energy deposition contribution. The experiment consisted of a CH foam cylinder, inside an external coaxial magnetic field of 5 T, that was imploded using 36 OMEGA laser beams. Two-dimensional (2D) hydrodynamic modelling predicts the CH density reaches 9.0 g cm − 3 , the temperature reaches 920 eV and the external B-field is amplified at maximum compression to 580 T. At pre-determined times during the compression, the intense OMEGA EP laser irradiated one end of the cylinder to accelerate relativistic electrons into the dense imploded plasma providing additional heating. The relativistic electron beam generation was simulated using a 2D particle-in-cell (PIC) code. Finally, three-dimensional hybrid-PIC simulations calculated the electron propagation and energy deposition inside the target and revealed the roles the compressed and self-generated B-fields play in transport. During a time window before the maximum compression time, the self-generated B-field on the compression front confines the injected electrons inside the target, increasing the temperature through Joule heating. For a stronger B-field seed of 20 T, the electrons are predicted to be guided into the compressed target and provide additional collisional heating. This article is part of a discussion meeting issue ‘Prospects for high gain inertial fusion energy (part 2)’.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

Spatio-temporally shaped deep UV laser source for ultrabright photocathodes using novel upconversion techniques (Final Report)

The goal of this project was to take a VUV laser system designed by Kapteyn-Murnane Labs (KMLabs)—the Hyperion VUV, and increase its functionality, efficiency, and applicability by further probing the fundamental physics taking place in the system and optimizing the system performance. More specifically, DOE accelerator applications—particularly for XFELs that require low-emittance electron beams, require precisely controlled ultrashort pulses in the deep-UV at 250-260 nm to drive the photocathode electron source. This is conventionally done using an ultrafast infrared laser, with subsequent stages of nonlinear upconversion in solid-state nonlinear-optical crystal media (principally BBO, which is commonly used for UV upconversion). However, maintaining high spatial mode beam quality, as well as precisely controlled temporal profile, has proven a persistent challenge. As a possible alternative to this approach, KMLabs has demonstrated a system that generates vacuum ultraviolet light (VUV) by upconverting pulses from an infrared ultrafast laser in a gas-filled hollow waveguide, driving a process of highly cascaded harmonic generation (HCHG). Because HCHG upconversion is done in a gas, rather than a solid, at high intensity in a guided-wave geometry, it retains an excellent beam spatial profile as well as a large spectral bandwidth that allows for control over the temperal structure of the pulse. A challenge, however, is in energy scaling of this HCHG technique to the ~1-20 μJ pulses required for photocathode applications. To-date, the pulse energies used in published HCHG work are sub-10-nJ. This project proposed to explore ways to generate higher-energy pulses using HCHG, as well as to investigate spectral and temporal shaping of the deep UV pulses by pulse shaping the infrared laser used to seed the process. Although we showed that our approach works for generating light at 259 nm, the total pulse energy achieved seems limited to approximately the same value as past work. However, the techniques we investigated may well have benefits for extending this source to much shorter wavelength output.

43 PARTICLE ACCELERATORS↗

Progress in Hybrid Plasma Wakefield Acceleration

Plasma wakefield accelerators can be driven either by intense laser pulses (LWFA) or by intense particle beams (PWFA). A third approach that combines the complementary advantages of both types of plasma wakefield accelerator has been established with increasing success over the last decade and is called hybrid LWFA→PWFA. Essentially, a compact LWFA is exploited to produce an energetic, high-current electron beam as a driver for a subsequent PWFA stage, which, in turn, is exploited for phase-constant, inherently laser-synchronized, quasi-static acceleration over extended acceleration lengths. The sum is greater than its parts: the approach not only provides a compact, cost-effective alternative to linac-driven PWFA for exploitation of PWFA and its advantages for acceleration and high-brightness beam generation, but extends the parameter range accessible for PWFA and, through the added benefit of co-location of inherently synchronized laser pulses, enables high-precision pump/probing, injection, seeding and unique experimental constellations, e.g., for beam coordination and collision experiments. We report on the accelerating progress of the approach achieved in a series of collaborative experiments and discuss future prospects and potential impact.

43 PARTICLE ACCELERATORS↗

Setting up a Rayleigh Scattering Based Flow Measuring System in a Large Nozzle Testing Facility

A molecular Rayleigh scattering based air density measurement system has been built in a large nozzle testing facility at NASA Glenn Research Center. The technique depends on the light scattering by gas molecules present in air; no artificial seeding is required. Light from a single mode, continuous wave laser was transmitted to the nozzle facility by optical fiber, and light scattered by gas molecules, at various points along the laser beam, is collected and measured by photon-counting electronics. By placing the laser beam and collection optics on synchronized traversing units, the point measurement technique is made effective for surveying density variation over a cross-section of the nozzle plume. Various difficulties associated with dust particles, stray light, high noise level and vibration are discussed. Finally, a limited amount of data from an underexpanded jet are presented and compared with expected variations to validate the technique.

Panda, Jayanta↗

Stormtime Particle Energization with AMIE Potentials

Simulations were conducted to investigate the influence of rapid electric field fluctuations on electron energization in the inner magnetosphere based on the assimilative mapping of ionospheric electrodynamics (AMIE) technique. Simulations for four different magnetic storms were run, namely those that occurred on May 15,1997, May 4, 1998, September 25, 1998, and October 19, 1998. Here, we have examined the formation of high energy electrons in the inner magnetosphere during these storm events with our recently-developed relativistic radiation belt transport code. The point of this numerical experiment is to show that a simulation of a real event must have the high time resolution electric field input files in order to produce the seed population for the radiation belts, which are often observed to increase in the days following a magnetic storm. Specifically, a cadence of the global electric field pattern of 5 minutes or less produces inner magnetospheric fluxes that are larger (by up to 5 orders of magnitude) than fluxes produced with a longer cadence. Differences were particularly large relative to simulation results with a 3-hour time cadence, analogous to a Kp-driven electric field model.

Khazanov, George V.↗

Power and particle exhaust for the ARC fusion power plant

To successfully show that fusion is an attractive energy source, the ARCTM fusion power plant will need to operate with a robust, integrated power and particle exhaust solution. To maximise ARC’s fusion power output while avoiding excessive erosion of the plasma-facing components, we will need to radiatively dissipate most of the power crossing the last-closed flux surface, injecting radiating impurities such as argon or neon to access divertor detachment. Divertor detachment will need to be integrated with a high-performance core plasma, and with efficient impurity pumping to prevent the accumulation of helium ash in the core. To access and control detachment in high-performance plasmas, we have designed ARC with up–down-symmetric divertors, with secondary X-points in long, tightly baffled outer legs. Using a core-edge modelling workflow, we predict that with this divertor design, ARC will access detachment with modest argon seeding in the divertor (c Ar,div ∼0.9%), which should have minimal impact on the core ( Z eff,core <0.5) for reasonable argon enrichment (c Ar,div /c Ar,core =6). Due to the high predicted divertor neutral pressure (p div ∼20 Pa), we predict that ARC will sufficiently pump helium to limit ash accumulation in the core (c He,core <2%) for a helium enrichment of c He,div /c He,core =0.4. ARC’s divertor design is expected to increase the stability of a detachment front in the outer divertor leg, helping to prevent divertor reattachment during smaller heat-flux transients such as scrape-off-layer filaments associated with the quasi-continuous exhaust regime. However, this buffering will not be sufficient to prevent divertor reattachment during large type-I edge-localised modes (ELMs), and as such these will need to be avoided on ARC. Experiments on SPARC will be used to select an integrated scenario which avoids or mitigates type-I-ELMs while maintaining access to detachment, good core fusion performance and sufficient impurity exhaust. SPARC experiments will also be used to finalise ARC’s divertor design, by studying the impact of magnetic and first-wall geometry on detachment stability, impurity enrichment and neutral baffling under conditions similar to those expected for ARC. In conclusion, our analysis finds that ARC will have a viable power and particle exhaust solution which is compatible with high-power operations, and this solution will be validated in experiments on SPARC.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

Recent and planned hydrodynamic instability experiments on indirect-drive implosions on the National Ignition Facility

At National Ignition Facility (NIF), yield amplification due to alpha particle heating approached ~3 in the highest performing inertial confinement fusion (ICF) implosions, while yield amplification of ~15-30 is needed for ignition. Hydrodynamic instabilities are a major factor in degradation of implosions while understanding and mitigation of the instabilities are critical to achieving ignition. This article describes recent and planned hydrodynamic instability experiments with several focused platforms that have been developed to directly measure these instabilities in all phases of ICF implosions. Measurements of ripple-shock generation at OMEGA laser have indicated initial seeds for the instabilities in three ablators - plastic (CH), beryllium, and high-density carbon (HDC). Hydrodynamic Growth Radiography (HGR) platform was used to measure instability growth at the ablation front in the acceleration phase of implosions. This platform used pre-imposed 2-D perturbations for growth factor measurements at different perturbation wavelengths and was also used to measure growth of “native roughness” modulations, fill tubes, and capsule support membranes or “tents”. Also, in the acceleration phase several new experimental platforms have been or are being developed to measure instability growth at the ablator-ice interface. In the deceleration phase of implosions, “self-emission” and “self-backlighting” platforms were developed to measure perturbations near peak compression. This article reviews recent progress and results.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

Stormtime Particle Energization with High Temporal Resolution AMIE Potentials

Simulations were conducted to investigate the influence of rapid electric field fluctuations on electron energization in the inner magnetosphere based on the assimilative mapping of ionospheric electrodynamics (AMIE) technique. Simulations for four different magnetic storms were run, namely those that occurred on 15 May 1997, 4 May 1998, 25 September 1998, and 19 October 1998. Here we have examined the formation of high- energy (100-500 keV) electrons in the inner magnetosphere during these storm events with our recently developed relativistic radiation belt transport code. The point of this numerical experiment is to show that a simulation of a real event must have the high time resolution electric field input files in order to produce the seed population for the radiation belts, which are often observed to increase in the days following a magnetic storm. Specifically, a cadence of the global electric field pattern of 5 min or less produces inner magnetospheric fluxes that are larger (by up to several orders of magnitude) than fluxes produced with a longer cadence. Differences were particularly large relative to simulation results with a 3-hour time cadence, analogous to a Kpdriven electric field model.

Khazanov, George V.↗

Hematite Crystallization from a Two-Line Ferrihydrite Suspension

Rational design and synthesis of materials, determination of environmental conditions at the time of mineral formation, and definition of mechanisms in biomineralizing systems all require an understanding of the effect of multiple factors on modulating crystallization pathways. In this study, we investigate the influence of temperature, oxalate additive, aging time, and addition of seed crystals on hematite (α-Fe 2 O 3 , Hm) crystallization from a two-line ferrihydrite (Fe 2 O 3 ·xH 2 O, Fh) suspension. We also investigate the effect of temperature on the aging of spindle-shaped Hm mesocrystals, which we synthesize through the addition of sodium oxalate. The results show that Hm mesocrystals form in a temperature window of 45 °C-130 °C. Temperatures ≥ 140 °C favor formation of rhombohedral Hm, suggesting classical monomer-by-monomer growth dominates, whereas crystallization by particle attachment (CPA) is dominant between 45 and 90 °C, while the two processes compete in the intermediate temperature range. Aging of mesocrystals in the original solution at 90 °C or 180 °C leads to a slow morphological evolution towards rhombohedral crystals due to Ostwald ripening. Then, by utilizing rhombohedral Hm and rod-shaped goethite as substrates on which to assemble the mesocrystals, we demonstrate formation of complex heterogeneous structures.

36 MATERIALS SCIENCE↗

Stormtime Particle Energization with High Temporal Resolution AMIE Potentials

Simulations were conducted to investigate the influence of rapid electric field fluctuations on electron energization in the inner magnetosphere based on the assimilative mapping of ionospheric electrodynamics (AMIE) technique. Simulations for four different magnetic storms were run, namely those that occurred on May 15, 1997, May 4, 1998, September 25, 1998, and October 19, 1998. Here, we have examined the formation of high energy (10-1000 keV) electrons in the inner magnetosphere during these storm events with our recently-developed relativistic radiation belt transport code. The point of this numerical experiment is to show that a simulation of a real event must have the high time resolution electric field input files in order to produce the seed population for the radiation belts, which are often observed to increase in the days following a magnetic storm. Specifically, a cadence of the global electric field pattern of 5 minutes or less produces inner magnetospheric fluxes that are larger (by up to several orders of magnitude) than fluxes produced with a longer cadence. Differences were particularly large relative to simulation results with a 3-hour time cadence, analogous to a Kp-driven electric field model.

Khazanov, George V.↗

Quantification of Aerosol Transmission through Stress Corrosion Crack-Like Geometries

The formation of a stress corrosion crack (SCC) in the canister wall of a dry cask storage system (DCSS) has been identified as a potential issue for the long-term storage of spent nuclear fuel. The presence of an SCC in a storage system could represent a through-wall flow path from the canister interior to the environment. Modern, vertical DCSSs are of particular interest due to the commercial practice of using more significant backfill pressures in the canister, up to approximately 800 kPa. This pressure differential offers a relatively high driving potential for blowdown of any particulates that might be present in the canister. In this study, the rates of gas flow and aerosol transmission of a spent fuel surrogate through an engineered microchannel with dimensions representative of an SCC were evaluated experimentally using coupled mass flow and aerosol analyzers. The microchannel was formed by mating two gage blocks with a linearly tapering slot orifice nominally 13 μm (0.005 in.) tall on the upstream side and 25 μm (0.0010 in.) tall on the downstream side. The orifice is 12.7 mm (0.500 in.) wide by 8.86 mm (0.349 in.) long (flow length). Surrogate aerosols of cerium oxide, CeO 2 , were seeded and mixed with either helium or air inside a pressurized tank. The aerosol characteristics were measured immediately upstream and downstream of the simulated SCC at elevated and ambient pressures, respectively. These data sets are intended to add to previous testing that characterized SCCs under well-controlled boundary conditions through the inclusion of testing improvements that establish initial conditions in a more consistent way. These ongoing testing efforts are focused on understanding the evolution in both size and quantity of a hypothetical release of aerosolized spent fuel particles from failed fuel to the canister interior and ultimately through an SCC.

12 MANAGEMENT OF RADIOACTIVE AND NON-RADIOACTIVE W↗

Temperature distributions of a cesium-seeded hydrogen-oxygen supersonic free jet

The hydrogen-oxygen plasma was generated at combustion chamber pressures ranging from 0.5 to 2.0 megapascals and for various seed ratios (1 to 10 percent). The plasma was observed as the atmospheric exhaust from a Mach 2 rocket test facility. Transverse profiles of the absolute integrated intensity were measured with the optically thin CsI lines (0.5664 and 0.5636 microns) at a range of axial positions downstream of the 5-cm-diameter combustor nozzle exit. Radial profiles of the emission coefficient were obtained from the measured transverse profiles of intensity by Abel inversion. Temperatures were then determined from the emission coefficients for conditions of local thermodynamic equilibrium using particle densities generated by a two-dimensional free jet computer program. Temperature results show the inherent effects of compression and expansion pressure waves characteristic of a free jet exiting from a supersonic nozzle.

Wang, S. Y.↗

Fundamental tests of galaxy formation theory

The structure of the universe as an environment where traces exist of the seed fluctuations from which galaxies formed is studied. The evolution of the density fluctuation modes that led to the eventual formation of matter inhomogeneities is reviewed, How the resulting clumps developed into galaxies and galaxy clusters acquiring characteristic masses, velocity dispersions, and metallicities, is discussed. Tests are described that utilize the large scale structure of the universe, including the dynamics of the local supercluster, the large scale matter distribution, and the anisotropy of the cosmic background radiation, to probe the earliest accessible stages of evolution. Finally, the role of particle physics is described with regard to its observable implications for galaxy formation.

Silk, J.↗

Application of Digital Particle Imaging Velocimetry to Turbomachinery

Digital Particle Imaging Velocimetry (DPIV) is a powerful measurement technique, which can be used as an alternative or complementary approach to Laser Doppler Velocimetry (LDV) in a wide range of research applications. The instantaneous planar velocity measurements obtained with PIV make it an attractive technique for use in the study of the complex flow fields encountered in turbomachinery. Many of the same issues encountered in the application of LDV to rotating machinery apply in the application of PIV. Techniques for optical access, light sheet delivery, CCD camera technology and particulate seeding are discussed. Results from the successful application of the PIV technique to both the blade passage region of a transonic axial compressor and the diffuser region of a high speed centrifugal compressor are presented. Both instantaneous and time-averaged flow fields were obtained. The 95% confidence intervals for the time-averaged velocity estimates were also determined. Results from the use of PIV to study surge in a centrifugal compressor are discussed. In addition, combined correlation/particle tracking results yielding super-resolution velocity measurements are presented.

Wernet, Mark P.↗