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At least 541 records · Page 30

Characterization of Radiation Exposure at Aviation Flight Altitudes Using the Nowcast of Aerospace Ionizing Radiation System (NAIRAS)

Exposure to ionizing radiation from galactic cosmic rays (GCRs) and solar energetic particles (SEPs) at aircraft flight altitudes can have an adverse effect on human health. Although airline crews are classified as radiation workers by the International Commission on Radiological Protection (ICRP), in most countries, their level of exposure is unquantified and undocumented throughout the duration of their career. As such, there is a need to assess pilot ionizing radiation exposure. The Nowcast of Aerospace Ionizing Radiation System (NAIRAS), a real-time global, physics-based model is used to assess such exposure. The Automated Radiation Measurements for Aerospace Safety (ARMAS) measurement dataset consists of high latitude, high altitude, and long-duration aircraft flights between 2013-2021. Here, we characterize radiation exposure at aviation flight altitudes using the NAIRAS model and compare with over 800 flight trajectories from the ARMAS flight measurement inventory.

Daniel B Phoenix↗

Improving Tornado Casualty Predictions in the US With Population Exposure Data and A Modified Social Vulnerability Index

Tornadoes are frequent and widespread events that often account for hundreds of injuries and fatalities, and millions of dollars in damages. Multiple studies have analyzed tornado climatology and associated exposure; however, fewer have focused on predicting fatalities and injuries by coupling geospatial data on tornado characteristics and underlying social and economic vulnerability. In this study, we test the ability of negative binomial regression models to predict tornado-induced injuries and fatalities by coupling data on physical characteristics of tornadoes, exposure of populations, and underlying social vulnerability. We also present a modified spatially weighted social vulnerability index SVI* wt . We used 10-year (2005-2014) tornado data over the continental United States for this analysis. The results of this study indicate that the tornado length, magnitude and nocturnality seem to be the major hazard-related indicators of fatalities (McFadden’s Pseudo- R 2 ranged from 0.01-0.12). Population exposure and SVI* wt are positive and statistically significant in predicting tornado related fatalities and injuries (Pseudo R 2 of 0.11-0.18). Although combining SVI* wt with hazard variables does not substantially improve model fit when compared to adding population exposure, combining SVI* wt , hazard and exposure results in better predictions of both injuries and fatalities (Pseudo R 2 of 0.17) and is also an improvement on previous similar studies.

disaster↗

Exposure of Plant Seeds to the Space Environment Outside the International Space Station

Crop seeds may prove to be a vital component of future long-term spaceflight missions, and the impacts of extended exposure on seed degradation is not well understood. The MISSE-Seed project was designed to investigate the effects of space exposure on seed quality and storage. The project also served as a test of biological materials aboard the Materials International Space Station Experiment (MISSE) platform, and evaluated the capability of a newly designed passive sample containment vessel for the provision of acceptable storage conditions for seed and other biological samples to be preserved upon exposure to the space environment outside the ISS. MISSE-Seed was launched to the ISS on NG-15 in July of 2021 and returned to Earth aboard SpX-24 after approximately 8 months of exposure to the space environment. The specimens consisted of eleven seed varieties (Lettuce, Scarlet Frills, Amara, Garnet Giant, Pac Choi, Radish, Mizuna, Tomato, Cauliflower, Pepper, and Arabidopsis). Data-loggers and thermoluminescent dosimeters (TLDs) were included in each container to record environmental data. Temperature profiles and radiation/UV exposure data were also provided by Aegis Aerospace, the MISSE Implementation Partner. Hardware and experimental design, environmental profiles, and post-flight germination and growth results will be presented.

Alexander D Meyers↗

Durability of Geopolymer Lunar Concrete From Exposure in Low Earth Orbit

Constructing infrastructure autonomously with concrete materials through additive manufacturing techniques on the lunar surface is a feasible option. The environmental and exposure conditions that the lunar concrete material will undergo are more extreme than on Earth and studying the durability aspect is important to scaling up the implementation of such materials. Conditions that the material will be exposed to include a hard vacuum, extreme temperatures, and ultraviolet radiation. To that end, geopolymer lunar concrete and ordinary portland cement paste samples were placed outside the International Space Station (ISS) for an approximate six-month exposure period. The samples were part of the 15th Materials International Space Station Experiment (MISSE-15) mission and were mounted in the zenith direction. After the exposure time, results for the samples exhibited discoloration, microstructural cracking, and an overall reduction in volume compared to data collected beforehand. The intent of this work was to characterize geopolymer lunar concrete durability in terms of the lunar environmental conditions in LEO and potential exposure scenarios from a simulated subscale rocket engine plume. To understand the durability of samples in space environment conditions, samples were placed outside the International Space Station (ISS) for a six-month period on the MISSE-FF. Additionally, to test the material's durability if implemented for use in a landing pad, samples were created for an experiment that mimics the exposure of the material to a rocket engine associated with the human lander system. This work is essential to progressing and scaling up geopolymer lunar concrete for implementation as the material's durability is assessed.

Peter J Collins↗

Characterization of Radiation Exposure at Aviation Flight Altitudes Using the Nowcast of Aerospace Ionizing Radiation System (NAIRAS)

Exposure to ionizing radiation from galactic cosmic rays (GCR) and solar energetic particles (SEP) at aircraft flight altitudes can have an adverse effect on human health. Although airline crews are classified as radiation workers by the International Commission on Radiological Protection (ICRP), in most countries, their level of exposure is unquantified and undocumented throughout the duration of their career. As such, there is a need to assess pilot ionizing radiation exposure. The Nowcast of Aerospace Ionizing Radiation System (NAIRAS), a real-time, global, physics-based model is used to assess such exposure. The Automated Radiation Measurements for Aerospace Safety (ARMAS) measurement dataset consists of high latitude, high altitude, and long-duration aircraft flights between 2013-2023. Here, we characterize radiation exposure at aviation flight altitudes using the NAIRAS model and compare with over 1000 flight trajectories from the ARMAS flight measurement inventory.

Daniel B Phoenix↗

Exposure of Highly Reflective Far-Ultraviolet Coatings to LEO Environment for TRL Advancement for the Habitable Worlds Observatory

Over the past several years, our team at the NASA Goddard Space Flight Center (GSFC), in collaboration with the Jet Propulsion Laboratory (JPL) and the Naval Research Laboratory (NRL), have developed several new protected Al coating technologies with improved Far-Ultraviolet (FUV) reflectance performance and more robust environmental stability. These include Al protected with lithium-based fluoride (LiF) coatings such as hot deposited LiF (eLiF), XeF 2 -passivated LiF coatings (XeLiF), Li 3 AlF 6 overcoats, AlF 3 (plasma passivated), and XeF 2 passivated MgF 2 coatings (XeMgF 2 ). However, despite these developments, relatively little experimental information exists regarding the long-term stability of these coatings after simultaneous exposure to the Low Earth Orbit (LEO) environment. To evaluate their environmental durability and advance their Technology Readiness Level (TRL), representative samples of these coating technologies, Al+XeLiF, Al+eLiF, Al+Li 3 AlF 6 , Al+AlF 3 , Al+XeMgF 2 , and bare Al as reference samples, were flown onboard the International Space Station (ISS) as part of the Materials International Space Station Experiment 20 (MISSE-20). The MISSE platform is operated by Aegis Aerospace for relatively long-duration (e.g. 6 months) external exposure experiments in a space environment. The coatings were deposited on ULE and Zerodur substrates, and witness samples deposited on the same coatings runs, but on glass slides were left on Earth as control. A subset of the flight samples were fitted with MgF 2 windows to reduce direct exposure to atomic oxygen (AO) and charged particles, and still let through UV and other types of radiation on these samples. After approximately 6 months of exposure in the forward-facing (RAM) direction, the samples were returned to Earth and characterized by performing FUV/NUV/VIS/NIR reflectance measurements to quantify degradation, spectroscopic ellipsometry to evaluate coating thickness and optical constants, atomic force microscopy (AFM) to quantify surface roughness evolution during the flight in the ISS. The MgF 2 protective windows were also analyzed through FUV transmission measurements. Comparison with the witness samples left on the ground and with the flown bare Al samples (with just the naturally occurring Al 2 O 3 layer) provided a quantitative assessment of coating thickness variations, optical performance degradation, and morphological changes induced by prolonged exposure to the LEO environment.

Far Ultraviolet (FUV)↗

Effects of Cell Phone Radiofrequency Signal Exposure on Brain Glucos Metabolism

The dramatic increase in use of cellular telephones has generated concern about possible negative effects of radiofrequency signals delivered to the brain. However, whether acute cell phone exposure affects the human brain is unclear. To evaluate if acute cell phone exposure affects brain glucose metabolism, a marker of brain activity. Randomized crossover study conducted between January 1 and December 31, 2009, at a single US laboratory among 47 healthy participants recruited from the community. Cell phones were placed on the left and right ears and positron emission tomography with ({sup 18}F)fluorodeoxyglucose injection was used to measure brain glucose metabolism twice, once with the right cell phone activated (sound muted) for 50 minutes ('on' condition) and once with both cell phones deactivated ('off' condition). Statistical parametric mapping was used to compare metabolism between on and off conditions using paired t tests, and Pearson linear correlations were used to verify the association of metabolism and estimated amplitude of radiofrequency-modulated electromagnetic waves emitted by the cell phone. Clusters with at least 1000 voxels (volume >8 cm{sup 3}) and P < .05 (corrected for multiple comparisons) were considered significant. Brain glucose metabolism computed as absolute metabolism ({micro}mol/100 g per minute) and as normalized metabolism (region/whole brain). Whole-brain metabolism did not differ between on and off conditions. In contrast, metabolism in the region closest to the antenna (orbitofrontal cortex and temporal pole) was significantly higher for on than off conditions (35.7 vs 33.3 {micro}mol/100 g per minute; mean difference, 2.4 [95% confidence interval, 0.67-4.2]; P = .004). The increases were significantly correlated with the estimated electromagnetic field amplitudes both for absolute metabolism (R = 0.95, P < .001) and normalized metabolism (R = 0.89; P < .001). In healthy participants and compared with no exposure, 50-minute cell phone exposure was associated with increased brain glucose metabolism in the region closest to the antenna. This finding is of unknown clinical significance.

38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEA↗

Lung function growth trajectories in non-asthmatic children aged 4–9 in relation to prenatal exposure to airborne particulate matter and polycyclic aromatic hydrocarbons – Krakow birth cohort study

Highlights: • The cohort of children has been followed from birth through the age of 9. • Individual growth trajectories of children's lung function in childhood were studied. • Prenatal exposure to airborne PM2.5 and PAHs on the growth rates was investigated. • High exposure to PM{sub 2.5} and PAH was associated with lower trajectories of FVC and FEV1. • High exposure to PM{sub 2.5} and PAH was not associated with the rate of increase over time. Patterns of lung function development during childhood can be helpful in understanding the pathogenesis of respiratory diseases. A variety of environmental and lifestyle factors, present from the prenatal period to adulthood, may affect or modulate lung function growth. The aim of this study was to investigate, the associations between individual growth trajectories of children's lung function during childhood and prenatal exposure to airborne fine particulate matter (PM{sub 2.5}) and polycyclic aromatic hydrocarbons (PAH), which were hypothesized to adversely affect spirometry parameters.

54 ENVIRONMENTAL SCIENCES↗

Home Nighttime Light Exposures: How much are we really getting?

This article summarizes the results of a survey of lighting professionals about the light levels in their homes, as measured at the eye. This should correspond better to estimates of light exposure for light and health concerns. It includes measurements of light exposure from interior and exterior light sources, as well as reading paper tasks, watching TV, and light exposure from cell phones and electronic tablets. The survey results are a pilot study to learn about actual light exposures at night in homes.

Light exposure, Exterior lighting, Bedroom lightin↗

Reducing Blood-borne Exposure in Interventional Radiology: What the IR Should Know

Interventional radiologists are at risk of exposure to blood-borne pathogens in their day-to-day practice. Percutaneous exposure from unsafe sharps handling, mucocutaneous exposure from body fluid splashes, and glove perforation from excessive wear can expose the radiologist to potentially infectious material. The increasing prevalence of blood-borne pathogens, including hepatitis B and C, and human immunodeficiency virus, puts nurses, residents, fellows, and interventional radiologists at risk for occupational exposure. This review outlines suggestions to establish a culture of safety in the interventional suite.

60 APPLIED LIFE SCIENCES↗

Assessing the use of portable air cleaners for reducing exposure to airborne diseases in a conference room with thermal stratification

The COVID-19 pandemic has highlighted the need for strategies that mitigate the risk of aerosol disease transmission in indoor environments with different ventilation strategies. It is necessary for building operators to be able to estimate and compare the relative impacts of different mitigation strategies to determine suitable strategies for a particular situation. Using a validated CFD model, this study simulates the dispersion of exhaled contaminants in a thermally stratified conference room with overhead heating. The impacts of portable air-cleaners (PACs) on the room airflow and contaminant distribution were evaluated for different PAC locations and flow rates, as well as for different room setups (socially distanced or fully occupied). To obtain a holistic view of a strategy's impacts under different release scenarios, we simultaneously model the steady-state distribution of aerosolized virus contaminants from eight distinct sources in 18 cases for a total of 144 release scenarios. The simulations show that the location of the source, the PAC settings, and the room set-up can impact the average exposure and PAC effectiveness. For this studied case, the PACs reduced the room average exposure by 31%-66% relative to the baseline case. Some occupant locations were shown to have a higher-than-average exposure, particularly those seated near the airflow outlet, and occupants closest to sources tended to see the highest exposure from said source. We found that these PACs were effective at reducing the stratification caused by overhead heating, and also identified at least one sub-optimal location for placing a PAC in this space.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗

Progress in cadmium-related health effects in persons with high environmental exposure in northwestern Thailand: A five-year follow-up

Food-borne cadmium was the principal source of exposure for persons living in the 12 cadmium-contaminated villages in Mae Sot District, Tak Province, northwestern Thailand. This report presents progress in cadmium-related health effects among persons with high cadmium exposure. The study included 436 persons who had urinary cadmium levels {>=}5 {mu}g/g creatinine and were screened for urinary cadmium, renal function, hypertension, diabetes and urinary stones in 2005 (baseline) and 2010 (5-year follow-up). Study renal biomarkers included urinary excretion of {beta}{sub 2}-microglobulin ({beta}{sub 2}-MG), total protein and calcium, serum creatinine and glomerular filtration rate (GFR). The geometric mean level of urinary cadmium statistically significantly reduced from 9.5{+-}1.6 {mu}g/g creatinine in 2005 to 8.8{+-}1.6 {mu}g/g creatinine in 2010. Compared to baseline, the follow-up examination revealed significant increases in urinary {beta}{sub 2}-MG (tubular effect), urinary total protein and serum creatinine, and a decrease in GFR (glomerular effects). Progressive renal dysfunctions were similarly observed in persons both with and without reduction in cadmium intake. Significant increases in prevalence of hypertension, diabetes and urinary stones were also detected at follow-up. These three disorders were found to markedly impair renal functions in the study persons. Our study indicates that in persons with prolonged excessive cadmium exposure, toxic health effects may progress even after exposure reduction. Renal damage from cadmium can be due to its direct nephrotoxic effect and also through the related disorders causing nephropathy.

54 ENVIRONMENTAL SCIENCES↗

Exposure to mercury among Spanish preschool children: Trend from birth to age four

The purpose of this study is to describe the total hair mercury concentrations and their determinants in preschool Spanish children, as well as to explore the trend in mercury exposure from birth to the age four. This evolution has been scarcely studied in other birth cohort studies. The study population was 580 four year old children participating in the INMA (i.e. Childhood and Environment) birth cohort study in Valencia (2008–2009). Total mercury concentration at age four was measured in hair samples by atomic absorption spectrometry. Fish consumption and other covariates were obtained by questionnaire. Multivariate linear regression models were conducted in order to explore the association between mercury exposure and fish consumption, socio-demographic characteristics and prenatal exposure to mercury. The geometric mean was 1.10 µg/g (95%CI: 1.02, 1.19). Nineteen percent of children had mercury concentrations above the equivalent to the Provisional Tolerable Weekly Intake proposed by WHO. Mercury concentration was associated with increasing maternal age, fish consumption and cord blood mercury levels, as well as decreasing parity. Children whose mothers worked had higher mercury levels than those with non working mothers. Swordfish, lean fish and canned fish were the fish categories most associated with hair mercury concentrations. We observed a decreasing trend in mercury concentrations between birth and age four. In conclusion, the children participating in this study had high hair mercury concentrations compared to reported studies on children from other European countries and similar to other countries with high fish consumption. The INMA study design allows the evaluation of the exposure to mercury longitudinally and enables this information to be used for biomonitoring purposes and dietary recommendations. - Highlights: • The geometric mean of hair Hg concentrations was 1.10 µg/g. • 19% of children had Hg concentrations above the RfD proposed by the WHO. • Hair Hg concentrations in children increased as a function of total fish intake. • Swordfish, lean fish and canned fish were the most related to Hg concentrations. • There was a decrease in Hg concentrations from birth to age four.

54 ENVIRONMENTAL SCIENCES↗

Iodine nutritional status and thyroid effects of exposure to ethylenebisdithiocarbamates

Introduction: Italy is still characterized by a mild iodine deficiency and is among the most intensive users of chemical products for agriculture in Europe. The aim of this study was i) to evaluate thyroid effects of exposure to mancozeb, a fungicide widely used in agriculture, in a sample of Italian grapevine workers, and ii) to verify whether the iodine intake may modulate the risk of thyroid disruption due to the mancozeb metabolite ethylenthiourea (ETU). Methods: One hundred seventy-seven occupationally exposed male workers (29 from Chianti, a mild iodine deficient area, and 148 from Bolzano an iodine sufficient province) and 74 non-occupationally exposed male controls (34 from Chianti and 40 from Bolzano) were enrolled in the study. Serum biomarkers of thyroid function, as well as urinary iodine and ETU concentrations were assessed. Moreover all the recruited subjects underwent clinical examination and thyroid ultrasound. Results: Multivariate comparisons showed lower mean serum levels of FT4 in Chianti-workers as compared to Bolzano-workers. Moreover, an increased urinary iodine excretion (>250 µg/L) was more frequently found among more exposed workers (ETU>20 µg/L) than among less exposed ones and this effect was more pronounced in Chianti- than in Bolzano-workers. Chianti-workers also showed a significantly higher frequency of very low thyroid volume (≤6.0 ml) as compared to controls. Conclusions: These findings showed a mild thyroid disrupting effect due to occupational exposure to mancozeb, more pronounced in workers residing in an area characterized by a mild to moderate iodine deficiency as compared to workers residing in an area covered by a long-lasting iodine prophylaxis program. - Highlights: • Thyroid is vulnerable to endocrine disrupting effects due to environmental exposures. • Mancozeb is a fungicide widely used in agriculture worldwide. • Mancozeb is broken down into ethylenthiourea (ETU) which has anti-thyroid activity. • Iodine intake may modulate thyroid disruption due to occupational exposure to ETU.

54 ENVIRONMENTAL SCIENCES↗

Combined effects of prenatal exposure to polycyclic aromatic hydrocarbons and material hardship on child ADHD behavior problems

Highlights: • PAH are common carcinogenic and neurotoxic combustion-related air pollutants. • Exposure to PAH tends to be disproportionately high in low income communities. • Prenatal PAH exposure was measured by PAH-DNA adducts in maternal blood. • We evaluated the combined effects of prenatal PAH and material hardship on ADHD. • We observed significant effects of combined exposures on ADHD behavior problems. Polycyclic aromatic hydrocarbons (PAH) are carcinogenic and neurotoxic combustion by-products commonly found in urban air. Exposure to PAH is disproportionately high in low income communities of color who also experience chronic economic stress.

54 ENVIRONMENTAL SCIENCES↗

Cognitive decline, mortality, and organophosphorus exposure in aging Mexican Americans

Highlights: • In a cohort of Mexican Americans, we examined how organophosphorus (OP) exposures influence cognitive decline and mortality. • Participants with high OP exposure in the 5-yrs prior to baseline experienced faster cognitive decline and higher mortality. • High OP exposure predicted lower levels of the metabolic hormone adiponectin, which mediated the OP-mortality association. Cognitive impairment is a major health concern among older Mexican Americans, associated with significant morbidity and mortality, and may be influenced by environmental exposures.

54 ENVIRONMENTAL SCIENCES↗

Mercury exposure and health impacts in dental personnel

Highlights: • Symptoms attributed to Hg frequently appear in dental personnel working with amalgam. • Symptoms of chronic low-level Hg{sup 0} exposure include weakness, fatigue, and anorexia. • It is crucial to protect human health and the environment against negative Hg effects. • World Health Organization (WHO) has recommended phasing out dental amalgam. Based on toxicological, clinical, and epidemiological knowledge, the present paper reviews the status regarding possible deleterious health effects from occupational exposure to metallic mercury (Hg) in dental practice. Symptoms from the central nervous system are among the health problems that most often are attributed to Hg exposure in dentists and dental nurses working with amalgam. Uncharacteristic symptoms of chronic low-level Hg vapor exposure including weakness, fatigue, and anorexia have been observed in numerous studies of dental personnel. It is crucial to protect both human health and the environment against negative effects of Hg. In line with this, the use of dental amalgam in industrial countries is about to be phased out. In Norway and Sweden, the use of the filling material is banned.

54 ENVIRONMENTAL SCIENCES↗

Results of lifespan exposure to continuous and intermittent extremely low frequency electromagnetic fields (ELFEMF) administered alone to Sprague Dawley rats

Highlights: • Carcinogenic effects of ELFEMF whole-body chronic exposure were evaluated on rats. • Exposure to ELFEMF alone does not represent risk factor for neoplastic development. • ELFEMF might act as a cancer enhancer if co-administered to other known carcinogens. Up to now, experimental studies on rodents have failed to provide definitive confirmation of the carcinogenicity of extremely low frequency electromagnetic fields (ELFEMF). Two recent studies performed in our laboratory on Sprague-Dawley rats reported a statistically significant increase in malignant tumors of different sites (mammary gland, C-cells carcinoma, hemolymphoreticular neoplasia, and malignant heart Schwannoma) when ELFEMF exposure was associated with exposure to formaldehyde (50 mg/l) or acute low dose of γ-radiation (0.1 Gy) (Soffritti et al., 2016a) (Soffritti et al., 2016b). The same doses of known carcinogenic agents (50 mg/l formaldehyde, or acute 0.1 Gy γ-radiation), when administered alone, previously failed to induce any statistically significant increase in the incidence of total and specific malignant tumors in rats of the same colony.

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTAN↗