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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 541 records · Page 30
All sourcesNASA NTRSDOE OSTI
DOE OSTI2016

Low frequency pulsed electromagnetic field promotes C2C12 myoblasts proliferation via activation of MAPK/ERK pathway

Low frequency pulsed electromagnetic field (PEMF) has been shown to affect the activity of various cell types and promote them proliferation. However, its effect on skeletal muscle cells remains to be determined. In our study, we confirmed that PEMF (100 Hz, 1 mT) could promote C2C12 myoblasts proliferation by using Cell Counting Kit-8 (CCK-8) and 5-Ethynyl-2’-deoxyuridine (EdU) assays, yet hardly any distinction was found in the rate of cell apoptosis between PEMF and control groups by flow cytometry (Annexin V-FITC/PI double staining method). To further study the mechanism of action of PEMF, Western blot was utilized to detect the mitogen-activated protein kinase (MAPK) signaling pathways. After exposing C2C12 myoblasts to PEMF, we found the phosphorylation level of extracellular signal-regulated kinase (ERK) was significantly increased, while p38 MAPK and c-Jun N-terminal kinase (JNK) pathways were not affected. Pretreating the cells with the ERK kinase1/2 (MEK1/2) inhibitor U0126 obviously inhibited the proliferation of C2C12 cells. Taken together, our research for the first time demonstrated that PEMF promoted C2C12 myoblasts proliferation via activating MAPK/ERK pathway.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗
DOE OSTI2017

Pulsed electromagnetic field inhibits RANKL-dependent osteoclastic differentiation in RAW264.7 cells through the Ca{sup 2+}-calcineurin-NFATc1 signaling pathway

Pulsed electromagnetic field (PEMF) has been reported to improve bone healing in osteoporosis patients. However, the precise mechanism has remained largely unknown. This study aimed to investigate the effects of PEMF on nuclear factor κB ligand (RANKL)-dependent osteoclastic differentiation and the Ca{sup 2+}-calcineurin-NFATc1 signaling pathway in RAW264.7 cells in vitro. Treating RAW264.7 cells with RANKL for 4 days induced osteoclastic differentiation in vitro, and the formation of multinucleated osteoclasts, bone resorption-pit formation, tartrate-resistant acid phosphatase (TRAP) activity and the protein levels of cathepsin K, TRAP, Nuclear factor of activated T-cells, cytoplasmic 1 (NFATc1) and matrix metalloproteinase 9 (MMP-9) were significantly decreased. The mRNA levels of specific genes related to osteoclastogenesis (TRAP, NFATc1, CTSK and MMP-9) were also reduced. Moreover, the oscillations of intracellular Ca{sup 2+} in RANKL-dependent RAW264.7 cells were suppressed by PEMF, as well as by inhibitors of membrane and store-operated Ca{sup 2+} channels. Meanwhile, calcineurin activity was increased, although its protein level was not changed. PEMF increased phospho-NFATc1 in the cytosol while suppressing the nuclear translocation of NFATc1, thus inhibiting osteoclastic differentiation by suppressing the Ca{sup 2+}-calcineurin-NFATc1 signaling pathway. Although many questions remain unresolved, to our knowledge, this is the first report demonstrating that PEMF is beneficial against RANKL-dependent osteoclastic differentiation in RAW264.7 cells in vitro via inhibiting the Ca{sup 2+}-calcineurin-NFATc1 signaling pathway.

60 APPLIED LIFE SCIENCES↗
DOE OSTI2018

Ultrahigh-order Maxwell solver with extreme scalability for electromagnetic PIC simulations of plasmas

The advent of massively parallel supercomputers, with their distributed-memory technology using many processing units, has favored the development of highly-scalable local low-order solvers at the expense of harder-to-scale global very high-order spectral methods. Indeed, FFT-based methods, which were very popular on shared memory computers, have been largely replaced by finite-difference (FD) methods for the solution of many problems, including plasmas simulations with electromagnetic Particle-In-Cell methods. For some problems, such as the modeling of so-called “plasma mirrors” for the generation of high-energy particles and ultra-short radiations, we have shown that the inaccuracies of standard FD-based PIC methods prevent the modeling on present supercomputers at sufficient accuracy. Here, we demonstrate here that a new method, based on the use of local FFTs, enables ultrahigh-order accuracy with unprecedented scalability, and thus for the first time the accurate modeling of plasma mirrors in 3D.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗
DOE OSTI2024

Numerical modeling of electromagnetic field spatiotemporal evolution to evaluate the effects on calcium carbonate crystallization

Calcium carbonate (CaCO 3 ) scaling is a significant impediment to water systems. Electromagnetic field (EMF) treatment is a promising approach to control scaling owing to its simplicity and low or no energy requirements. However, the underlying mechanisms by which EMF impacts CaCO 3 crystallization remain unclear due to the challenges in measuring the EMFs in feed solutions and the lack of a fundamental understanding of the applied EMFs and the observed physicochemical phenomena. To fill this knowledge gap, a high-fidelity COMSOL model was first developed to simulate EMFs in bulk solutions for three alternating current-induced EMF devices with different configurations and properties. These were then integrated with experimental data to unveil the underlying mechanism by which applied EMFs alter the physicochemical processes. The study revealed that even low-strength EMFs (e.g., electric fields <0.15 V/m and magnetic fields <0.03 mT) promoted CaCO 3 precipitation in bulk solutions. The electric fields created by these EMF devices resulted in higher Lorentz force compared to their induced magnetic fields. In conclusion, the methodology of this study offers the capability to predict the effectiveness of different EMF devices in facilitating crystallization processes, and these mechanistic insights lay the foundation for the smart design of EMF devices for diverse water treatment applications.

COMSOL simulation↗
DOE OSTI2013

Assessment of outdoor radiofrequency electromagnetic field exposure through hotspot localization using kriging-based sequential sampling

In this study, a novel methodology is proposed to create heat maps that accurately pinpoint the outdoor locations with elevated exposure to radiofrequency electromagnetic fields (RF-EMF) in an extensive urban region (or, hotspots), and that would allow local authorities and epidemiologists to efficiently assess the locations and spectral composition of these hotspots, while at the same time developing a global picture of the exposure in the area. Moreover, no prior knowledge about the presence of radiofrequency radiation sources (e.g., base station parameters) is required. After building a surrogate model from the available data using kriging, the proposed method makes use of an iterative sampling strategy that selects new measurement locations at spots which are deemed to contain the most valuable information—inside hotspots or in search of them—based on the prediction uncertainty of the model. The method was tested and validated in an urban subarea of Ghent, Belgium with a size of approximately 1 km{sup 2}. In total, 600 input and 50 validation measurements were performed using a broadband probe. Five hotspots were discovered and assessed, with maximum total electric-field strengths ranging from 1.3 to 3.1 V/m, satisfying the reference levels issued by the International Commission on Non-Ionizing Radiation Protection for exposure of the general public to RF-EMF. Spectrum analyzer measurements in these hotspots revealed five radiofrequency signals with a relevant contribution to the exposure. The radiofrequency radiation emitted by 900 MHz Global System for Mobile Communications (GSM) base stations was always dominant, with contributions ranging from 45% to 100%. Finally, validation of the subsequent surrogate models shows high prediction accuracy, with the final model featuring an average relative error of less than 2 dB (factor 1.26 in electric-field strength), a correlation coefficient of 0.7, and a specificity of 0.96. -- Highlights: • We present an iterative measurement and modeling method for outdoor RF-EMF exposure. • Hotspots are rapidly identified, and accurately characterized. • An accurate graphical representation, or heat map, is created, using kriging. • Random validation shows good correlation (0.7) and low relative errors (2 dB)

61 RADIATION PROTECTION AND DOSIMETRY↗
DOE OSTI2018

Assessment of long-term spatio-temporal radiofrequency electromagnetic field exposure

Highlights: • A year's worth of RF-EMF data is collected in an urban sensor network is analysed. • A full spatio-temporal model of the RF-EMF exposure in the study area is built. • Short-term variations of the RF-EMF exposure are collected in temporal profiles. • Models using data collected at different instants are improved by adjusting for time. As both the environment and telecommunications networks are inherently dynamic, our exposure to environmental radiofrequency (RF) electromagnetic fields (EMF) at an arbitrary location is not at all constant in time. In this study, more than a year's worth of measurement data collected in a fixed low-cost exposimeter network distributed over an urban environment was analysed and used to build, for the first time, a full spatio-temporal surrogate model of outdoor exposure to downlink Global System for Mobile Communications (GSM) and Universal Mobile Telecommunications System (UMTS) signals. Though no global trend was discovered over the measuring period, the difference in measured exposure between two instances could reach up to 42 dB (a factor 12,000 in power density). Furthermore, it was found that, taking into account the hour and day of the measurement, the accuracy of the surrogate model in the area under study was improved by up to 50% compared to models that neglect the daily temporal variability of the RF signals. However, further study is required to assess the extent to which the results obtained in the considered environment can be extrapolated to other geographic locations.

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTAN↗
DOE OSTI2018

Representativeness and repeatability of microenvironmental personal and head exposures to radio-frequency electromagnetic fields

Highlights: • First time assessment of head exposure to RF-EMF in uncontrolled environments, in 15 microenvironments in Melbourne, Australia. • We show that our measurement protocol is repeatable over time. • We show that the paths selected in our protocol are representative for the larger areas in which they are defined. • Exposure to RF-EMF is higher in more dense urban areas than in less populated suburban areas in the outskirts of the city. The aims of this study were to: i) investigate the repeatability and representativeness of personal radio frequency-electromagnetic fields (RF-EMFs) exposure measurements, across different microenvironments, ii) perform simultaneous evaluations of personal RF-EMF exposures for the whole body and the head, iii) validate the data obtained with a head-worn personal distributed exposimeter (PDE) against those obtained with an on-body worn personal exposimeter (PEM). Data on personal and head RF-EMF exposures were collected by performing measurements across 15 microenvironments in Melbourne, Australia. A body-worn PEM and a head-worn PDE were used for measuring body and head exposures, respectively. The summary statistics obtained for total RF-EMF exposure showed a high representativeness (r{sup 2} > 0.66 for two paths in the same area) and a high repeatability over time (r{sup 2} > 0.87 for repetitions of the same path). The median head exposure in the 900 MHz downlink band ranged between 0.06 V/m and 0.31 V/m. The results obtained during simultaneous measurements using the two devices showed high correlations (0.42 < r{sup 2} < 0.94). The highest mean total RF-EMF exposure was measured in Melbourne's central business district (0.89 V/m), whereas the lowest mean total exposure was measured in a suburban residential area (0.05 V/m). This study shows that personal RF-EMF microenvironmental measurements in multiple microenvironments have high representativeness and repeatability over time. The personal RF-EMF exposure levels (i.e. body and head exposures) demonstrated moderate to high correlations.

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTAN↗
DOE OSTI2018

Genotoxic and carcinogenic effects of non-ionizing electromagnetic fields

Highlights: • Public concern over the effects of EMF on cancer is growing. • In vitro and in vivo experiments concerning ELF and EMF have elicited contradictory results. • Epidemiological studies may help us to understand the genotoxic and carcinogenic effects of EMF. • Do adverse effects differ depending on the EMF frequency involved? New technologies in electronics and communications are continually emerging. An increasing use of these electronic devices such as mobile phone, computer, wireless fidelity connectors or cellular towers is raising questions concerning whether they have an adverse effect on the body. Exposure to electromagnetic fields (EMF) is frequently suggested to have adverse health effects on humans and other organisms. This idea has been reported in many studies. In contrast, the therapeutic effects of EMF on different organs have also been reported. Research findings are inconsistent. This has given rise to very profound discrepancies. The duration and frequency of mobile phone calls and the association observed with various health effects has raised serious concerns due to the frequency with which these devices are used and the way they are held close to the head. The present review assesses the results of in vitro, in vivo, experimental, and epidemiological studies. The purpose of the study is to assess data concerning the carcinogenic and genotoxic effects of non-ionizing EMF. The major genotoxic and carcinogenic effects of EMF, divided into subsections as low frequency effects and radiofrequency effects, were reviewed. The inconsistent results between similar studies and the same research groups have made it very difficult to make any comprehensive interpretation. However, evaluation of current studies suggests that EMF may represent a serious source of concern and may be hazardous to living organisms.

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTAN↗
DOE OSTI2018

Results of lifespan exposure to continuous and intermittent extremely low frequency electromagnetic fields (ELFEMF) administered alone to Sprague Dawley rats

Highlights: • Carcinogenic effects of ELFEMF whole-body chronic exposure were evaluated on rats. • Exposure to ELFEMF alone does not represent risk factor for neoplastic development. • ELFEMF might act as a cancer enhancer if co-administered to other known carcinogens. Up to now, experimental studies on rodents have failed to provide definitive confirmation of the carcinogenicity of extremely low frequency electromagnetic fields (ELFEMF). Two recent studies performed in our laboratory on Sprague-Dawley rats reported a statistically significant increase in malignant tumors of different sites (mammary gland, C-cells carcinoma, hemolymphoreticular neoplasia, and malignant heart Schwannoma) when ELFEMF exposure was associated with exposure to formaldehyde (50 mg/l) or acute low dose of γ-radiation (0.1 Gy) (Soffritti et al., 2016a) (Soffritti et al., 2016b). The same doses of known carcinogenic agents (50 mg/l formaldehyde, or acute 0.1 Gy γ-radiation), when administered alone, previously failed to induce any statistically significant increase in the incidence of total and specific malignant tumors in rats of the same colony.

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTAN↗
DOE OSTI2024

Validation of Phasor-Domain Transmission and Distribution Co-simulation Against Electromagnetic Transient Simulation

The rapid deployment of renewable energy resources has led to the widespread use of power electronics in modern power systems. As these systems transition from being dominated by large synchronous machines to increasingly incorporating inverter-based resources (IBRs), traditional methods are becoming inadequate. Addressing this challenge, this paper introduces a scalable phasor-domain T\&D co-simulation framework based on open-source software. It focuses on the framework's validation against the PSCAD Electromagnetic Transient (EMT) analysis tool. The validation results demonstrate the framework's high-fidelity and a computational time speed-up of 60 to 100 times, marking a pioneering validation effort in T\&D co-simulation research.

Inverter-based resources, co-simulation, Electroma↗
DOE OSTI2024

Iron-sandstone synergy: Advancing in-situ hydrogen production from natural gas via electromagnetic heating

Here, to address the escalating demands for decarbonization in the petroleum industry, a carbon-zero technology, known as in-situ hydrogen (H 2 ) production via electromagnetic (EM)-assisted catalytic heating, has recently been proposed for generating and extracting clean H 2 directly from petroleum reservoirs. Although preliminary techno-economic analyses show significant potential of this emerging technology for clean and affordable hydrogen, the fundamentals of natural gas conversion to H 2 in the presence of reservoir rocks are poorly understood. In this study, we explore the synergy between sandstone and artificial iron-based catalysts in enhancing in-situ H 2 production from methane (CH 4 ) cracking under EM irradiation. The dynamic behaviors of sandstone under EM heating are comprehensively investigated, including its thermal behaviors, thermal runaway (TR) phenomenon, gas generation during TR, and energy consumption. We found that sandstone demonstrates an evident natural catalytic effect for promoting CH 4 conversion to H 2 , enabling H 2 production starting at about 394 °C. The natural catalytic role of iron minerals in sandstone is elucidated using various advanced characterization techniques. Remarkably, when adding iron catalysts into the sandstone, the highest H 2 concentration and CH 4 conversion reaches 91 mol.% and 80%, respectively, at a temperature of 666 °C, while they are 50 mol.% and 35%, respectively, for the sample consisting of iron catalysts and quartz at the same level of temperature. This result indicates a strong iron-sandstone synergy and a potential to stimulate H 2 production by leveraging this synergy. Throughout the experimental process, the generation of carbon oxides (CO and CO 2 ) is negligible. These findings pave a pathway towards future pilot for carbon-zero in-situ H 2 production from sandstone gas reservoirs.

03 NATURAL GAS↗
DOE OSTI2013

Influence of numerical schemes on statistical properties of computed charged particle trajectories in turbulent electromagnetic fields

A class of numerical schemes is developed for the study of charged particle transport in complex stationary electromagnetic fields and tested for fields obtained from a numerical solution of the magneto-hydrodynamic equation. The performances of these schemes are evaluated by analyzing the conservation of energy and the statistical properties of the trajectories. Energy conservation is affected by the interpolation technique used to estimate the field value at the particle position. However, the particle transport properties are more robust, except in the limit of low energy when a significant fraction of the particles are trapped.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗
DOE OSTI2014

Phase field method to optimize dielectric devices for electromagnetic wave propagation

We discuss a phase field method for shape optimization in the context of electromagnetic wave propagation. The proposed method has the same functional capabilities as the level set method for shape optimization. The first advantage of the method is the simplicity of computation, since extra operations such as re-initialization of functions are not required. The second is compatibility with the topology optimization method due to the similar domain representation and the sensitivity analysis. Structural shapes are represented by the phase field function defined in the design domain, and this function is optimized by solving a time-dependent reaction diffusion equation. The artificial double-well potential function used in the equation is derived from sensitivity analysis. We study four types of 2D or 2.5D (axisymmetric) optimization problems. Two are the classical problems of photonic crystal design based on the Bloch theory and photonic crystal wave guide design, and two are the recent topics of designing dielectric left-handed metamaterials and dielectric ring resonators.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗
DOE OSTI2014

Numerical approximation of the Schrödinger equation with the electromagnetic field by the Hagedorn wave packets

In this paper, we approximate the semi-classical Schrödinger equation in the presence of electromagnetic field by the Hagedorn wave packets approach. By operator splitting, the Hamiltonian is divided into the modified part and the residual part. The modified Hamiltonian, which is the main new idea of this paper, is chosen by the fact that Hagedorn wave packets are localized both in space and momentum so that a crucial correction term is added to the truncated Hamiltonian, and is treated by evolving the parameters associated with the Hagedorn wave packets. The residual part is treated by a Galerkin approximation. We prove that, with the modified Hamiltonian only, the Hagedorn wave packets dynamics give the asymptotic solution with error O(ε{sup 1/2}), where ε is the scaled Planck constant. We also prove that, the Galerkin approximation for the residual Hamiltonian can reduce the approximation error to O(ε{sup k/2}), where k depends on the number of Hagedorn wave packets added to the dynamics. This approach is easy to implement, and can be naturally extended to the multidimensional cases. Unlike the high order Gaussian beam method, in which the non-constant cut-off function is necessary and some extra error is introduced, the Hagedorn wave packets approach gives a practical way to improve accuracy even when ε is not very small.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗
DOE OSTI2015

Second order finite volume scheme for Maxwell's equations with discontinuous electromagnetic properties on unstructured meshes

This paper presents a second order finite volume scheme for numerical solution of Maxwell's equations with discontinuous dielectric permittivity and magnetic permeability on unstructured meshes. The scheme is based on Godunov scheme and employs approaches of Van Leer and Lax–Wendroff to increase the order of approximation. To keep the second order of approximation near dielectric permittivity and magnetic permeability discontinuities a novel technique for gradient calculation and limitation is applied near discontinuities. Results of test computations for problems with linear and curvilinear discontinuities confirm second order of approximation. The scheme was applied to modelling propagation of electromagnetic waves inside photonic crystal waveguides with a bend.

75 CONDENSED MATTER PHYSICS, SUPERCONDUCTIVITY AND↗
DOE OSTI2014

Performance of the first prototype of the CALICE scintillator strip electromagnetic calorimeter

A first prototype of a scintillator strip-based electromagnetic calorimeter was built, consisting of 26 layers of tungsten absorber plates interleaved with planes of 45 × 10 × 3 mm³ plastic scintillator strips. Data were collected using a positron test beam at DESY with momenta between 1 and 6 GeV/c. The prototype's performance is presented in terms of the linearity and resolution of the energy measurement. These results represent an important milestone in the development of highly granular calorimeters using scintillator strip technology. A number of possible design improvements were identified, which should be implemented in a future detector of this type. This technology is being developed for a future linear collider experiment, aiming at the precise measurement of jet energies using particle flow techniques.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗
DOE OSTI2018

Construction and response of a highly granular scintillator-based electromagnetic calorimeter

Here, a highly granular electromagnetic calorimeter with scintillator strip readout is being developed for future linear collider experiments. A prototype of 21.5 X 0 depth and 180 × 180 mm 2 transverse dimensions was constructed, consisting of 2160 individually read out 10 × 45 × 3 mm 3 scintillator strips. This prototype was tested using electrons of 2–32 Ge V at the Fermilab Test Beam Facility in 2009. Deviations from linear energy response were less than 1.1%, and the intrinsic energy resolution was determined to be ( 12 . 5 ± 0 . 1 ( stat. ) ± 0 . 4 ( syst. ) ) % / E [ Ge V ] ⊕ ( 1 . 2 ± 0 . 1 ( stat. ) - 0 . 7 + 0 . 6 ( syst. ) ) % , where the uncertainties correspond to statistical and systematic sources, respectively.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗
DOE OSTI2018

Construction and performance of the barrel electromagnetic calorimeter for the Gluex experiment

The barrel calorimeter is part of the new spectrometer installed in Hall D at Jefferson Lab for the GlueX experiment. The calorimeter was installed in 2013, commissioned in 2014 and has been operating routinely since early 2015. The detector configuration, associated Monte Carlo simulations, calibration and operational performance are described in this paper. The calorimeter records the time and energy deposited by charged and neutral particles created by a multi-GeV photon beam. It is constructed as a lead and scintillating-fiber calorimeter and read out with 3840 large-area silicon photomultiplier arrays. Particles impinge on the detector over a wide range of angles, from normal incidence at 90 degrees down to 11.5 degrees, which defines a geometry that is fairly unique among calorimeters. The response of the calorimeter has been measured during a running experiment and performs as expected for electromagnetic showers below 2.5 GeV. Finally, we characterize the performance of the BCAL using the energy resolution integrated over typical angular distributions for π 0 and η production of σ E / E = 5 . 2 % / E ( GeV ) ⊕ 3 . 6 % and a timing resolution of σ = 150 ps at 1 GeV.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗