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At least 541 records · Page 30

Dose Rate Effects on Degradation of Nuclear Power Plant Electrical Cable Insulation at a Common Dose

The intent of this report is to address an identified knowledge gap in relating accelerated aging of nuclear electrical cables to service aging: dose rate effects (DRE). Here, DRE refer to gamma radiation-induced polymer degradation being a function of dose rate in addition to total absorbed dose. The concern raised is that historical qualification conducted at higher dose rates to simulate service lifetime may underestimate insulation degradation that occurs at lower dose rates in service. In the work described herein, common nuclear cable insulation materials—cross-linked polyethylene (XLPE) and ethylene propylene diene elastomer (EPDM)—were subjected to accelerated aging at ambient temperature (26°C) at different gamma dose rates of 100, 200 and 1800 Gy/h for select exposure durations to achieve constant total doses of 170, 210 and 300 kGy to evaluate DRE. First, the cable insulation material types investigated are described. Then, the accelerated aging experimental process involving gamma irradiation applied to the insulation specimens at room temperature and different dose rates is discussed. Then, the experimental characterization techniques used to perform this work are elucidated. These include elongation at break (EAB), mass change, yellowness index (YI), carbonyl index (CI), density, indenter modulus (IM), and relaxation constant (t). Theory of polymer degradation is discussed, and characterization results and discussion are provided. Finally, concluding remarks are made. The findings from this work and cited prior work reveal that DRE are material dependent, even between similar material categories (e.g., XLPE). In the case of the EPDM studied, degradation of ductility was observed to be greater at higher dose rate for the same total dose, indicating accelerated gamma aging to be more conservative than extended aging. Thus, conclusions regarding the conservatism of historical qualification likely require additional consideration for specific materials and conditions in question. The results of this study support the contention that, due to inherent limitations and uncertainties associated with prediction of cable remaining useful life from accelerated aging experiments, trending of installed cable insulation health status will be more practical and useful for safe and efficient cable aging management repair and replace decisions than lifetime prediction from historical qualification. The combination of material robustness demonstrated by the qualification process and ongoing monitoring of cable health status combine to provide confidence in continued safe use of existing nuclear cables. Additional research into effective and efficient condition monitoring methods for non-destructive evaluation of installed cables is needed to support aging cable management, including material studies to inform interpretation of measured results.

21 SPECIFIC NUCLEAR REACTORS AND ASSOCIATED PLANTS↗

The LANL Common Modeling Framework (CMF) [Slides]

The Common Modeling Framework is a modern software repository built and maintained by the LANL Weapons Physics Directorate (ALDX). ALDX’s mission space is to develop and apply cutting-edge theory, computational models, and multi-physics simulation codes, and to design, execute, and analyze complex experiments

97 MATHEMATICS AND COMPUTING↗

Distribution System Model Calibration for GMLC 3.3.3 "Incipient Failure Identification for Common Grid Asset Classes" - Project Summary

Distribution system model calibration is a key enabling task for incipient failure identification within the distribution system. This report summarizes the work and publications by Sandia National Laboratories on the GMLC project titled “Incipient Failure Identification for Common Grid Asset Classes”. This project was a joint effort between Sandia National Laboratories, Lawrence Livermore National Laboratory, National Energy Technology Laboratory, and Oak Ridge National Laboratory. The included work covers distribution system topology identification, transformer groupings, phase identification, regulator and tap position estimation, and the open-source release and implementation of the developed algorithms.

24 POWER TRANSMISSION AND DISTRIBUTION↗

Application of aerosol-ice nucleating particle closure to establish the leading parameters governing ice crystal number concentration under commonly observed mixed-phase cloud conditions

This is the final technical report for DOE DE-SC0021034 award entitled “Application of aerosol-ice nucleating particle closure to establish the leading parameters governing ice crystal number concentration under commonly observed mixed-phase cloud conditions”. The overarching objective of this project was to gain a predictive understanding of the processes that lead from aerosols to ice-nucleating particles (INPs) to ice crystal number concentrations (ICNCs) in stratiform mixed-phase clouds where supercooled water droplets and ice crystals coexist, and to inform climate model parameterizations. During this four-year project we addressed the three main research goals of this objective: 1) Study the aerosol-INP link; 2) Develop an aerosol-cloud column model (AC-1D); and 3) Study the INP-ICNC link. Those activities significantly advanced our predictive understanding of how to represent INPs in could models and its implications on ice crystal number concentrations. The results have been published in five peer-reviewed publications with three more in review and preparation. It allowed for collaboration resulting in additional fourteen peer-reviewed publications that are concerned with the objective of this research project. This research has been communicated to the scientific community at national and international meetings and conferences by numerous talks, seminars, and posters including fifteen invited presentations. This project allowed training of four graduate students and one postdoctoral research associate resulting in one M.S. thesis and advancement to Ph.D. candidacy.

54 ENVIRONMENTAL SCIENCES↗

Evaluation of the Self Retrieval Augmented Generation Technique on Common Security Advisory Framework Data

This small experimental report evaluates a variation of Retrieval Augmented Generation (RAG), called Self-RAG. This method uses a generative language model that incorporates retrieved facts into its generation and is explicitly trained to be able to determine whether retrieved information is enough to answer the input query, with a user-defined threshold for confidence. We performed an experiment using data from the publicly available CISA Common Security Advisory Framework (CSAF) repository (https://github.com/cisagov/CSAF) as the database of facts to be used in retrieval. Qualitative results from the experiment demonstrate that the Self-RAG method has some ability to provide reasonable answers to queries that are in the dataset and will often ignore irrelevant information when asked outside of domain questions (e.g., general facts). In settings with deliberately confusing questions (the question is within domain, but asks about a fabricated advisory), it was able to refuse 40% of the time without further adjustments to the original framework. While this performance is not sufficient for current practical use, further improvements to data formatting, disambiguating results, and leveraging threshold values could improve performance significantly. However, evaluating this will require more extensive evaluations on larger datasets and potentially better models.

97 MATHEMATICS AND COMPUTING↗

Restoring Homes After Wildfires, Interviews with Practitioners about Common Cleanup Approaches and Knowledge Gaps

This document summarizes the key themes from our interviews with 10 remediation companies regarding common approaches used to remove odor and contaminants from homes impacted by fire and smoke damage Remediation companies are in agreement that thorough cleaning is the first step. Cleaning and removing contaminants from homes impacted by wildfires may be sufficient to eliminate smoke odor, which is the most important step when it comes to reducing exposure to any residues that may pose health risks to residents. Remediation companies differ in their approaches to addressing odors, such as using ozone generators, hydroxyl generators, chlorine dioxide treatment, thermal fogging and applying sealants. Their opinions of what works and why differs. There is little consensus on efficacy, safety, or application protocols. For example, some view ozone very favorably, while others would prefer using other methods. The influence of insurance companies in their coverage for some methods but not others also impact the decision about the approaches used. Remediation companies differ in their view on laboratory testing for contaminants, which may be partly influenced by insurance companies as well.

99 GENERAL AND MISCELLANEOUS↗

Blueprint: Open Worldwide Application Security Project Top 10 Common Weakness Enumerations for Electric Vehicle Supply Equipment

This report categorizes the top 10 security weaknesses in electric vehicle supply equipment (EVSE) using a similar approach by the Open Worldwide Application Security Project (OWASP) Top 10, and it describes example exploitations, methods for prevention, and related common weakness enumerations (CWEs) for each category. The weaknesses listed in this report could lead to security issues or vulnerabilities in EVSE if they are exploited by an attacker to compromise the confidentiality, integrity, or availability of a system. This report also recommends EVSE industry best practices and remediations for the identified weaknesses to use as guidelines for their secure products and systems.

33 ADVANCED PROPULSION SYSTEMS↗

Delayed HIV diagnosis common in Sweden, 2003–2010

Background: Early diagnosis of HIV is important for the prognosis of individual patients, because antiretroviral treatment can be started at the appropriate time, and for public health, because transmission can be prevented. Methods: Data were collected from 767 HIV patients who were diagnosed in Sweden during 2003–2010 and were infected in Sweden or born in Sweden and infected abroad. A recent infection testing algorithm (RITA) was applied to BED-EIA test results (OD-n < 0.8), CD4 counts (≥ 200 cells/μl), and clinical information. A recent infection classification was used as indicator for early diagnosis. Time trends in early diagnosis were investigated to detect population changes in HIV testing behavior. Patients with early diagnosis were compared to patients with delayed diagnosis with respect to age, gender, transmission route, and country of infection (Sweden or abroad). Results: Early diagnosis was observed in 271 patients (35%). There was no statistically significant time trend in the yearly percentage of patients with early diagnosis in the entire study group (p = 0.836) or in subgroups. Early diagnosis was significantly more common in men who have sex men (MSM) (45%) than in heterosexuals (21%) and injecting drug users (27%) (p < 0.001 and p = 0.001, respectively) in both univariate and multivariable analyses. The only other factor that remained associated with early diagnosis in multivariable analysis was young age group. Conclusion: Approximately one-third of the study patients were diagnosed early with no significant change over time. Delayed HIV diagnosis is a considerable problem in Sweden, which does not appear to diminish.

delayed diagnosis↗

Applying the core-satellite species concept: Characteristics of rare and common riverine dissolved organic matter

Introduction: Dissolved organic matter (DOM) composition varies over space and time, with a multitude of factors driving the presence or absence of each compound found in the complex DOM mixture. Compounds ubiquitously present across a wide range of river systems (hereafter termed core compounds) may differ in chemical composition and reactivity from compounds present in only a few settings (hereafter termed satellite compounds). Here, we investigated the spatial patterns in DOM molecular formulae presence (occupancy) in surface water and sediments across 97 river corridors at a continental scale using the “Worldwide Hydrobiogeochemical Observation Network for Dynamic River Systems—WHONDRS” research consortium. Methods: We used a novel data-driven approach to identify core and satellite compounds and compared their molecular properties identified with Fourier-transform ion cyclotron resonance mass spectrometry (FT-ICR MS). Results: In this work, we found that core compounds clustered around intermediate hydrogen/carbon and oxygen/carbon ratios across both sediment and surface water samples, whereas the satellite compounds varied widely in their elemental composition. Within surface water samples, core compounds were dominated by lignin-like formulae, whereas protein-like formulae dominated the core pool in sediment samples. In contrast, satellite molecular formulae were more evenly distributed between compound classes in both sediment and water molecules. Core compounds found in both sediment and water exhibited lower molecular mass, lower oxidation state, and a higher degree of aromaticity, and were inferred to be more persistent than global satellite compounds. Higher putative biochemical transformations were found in core than satellite compounds, suggesting that the core pool was more processed. Discussion: The observed differences in chemical properties of core and satellite compounds point to potential differences in their sources and contribution to DOM processing in river corridors. Overall, our work points to the potential of data-driven approaches separating rare and common compounds to reduce some of the complexity inherent in studying riverine DOM.

54 ENVIRONMENTAL SCIENCES↗

Influence of Common Assumptions Regarding Aerosol Composition and Mixing State on Predicted CCN Concentration

A 4-year record of aerosol size and hygroscopic growth factor distributions measured at the Department of Energy’s Southern Great Plains (SGP) site in Oklahoma, U.S. were used to estimate supersaturation (S)-dependent cloud condensation nuclei concentrations (N CCN ). Baseline or reference N CCN (S) spectra were estimated using κ-Köhler Theory without any averaging of the measured distributions by creating matrices of size- and hygroscopicity-dependent number concentration (N) and then integrating for S > critical supersaturation (S c ) calculated for the same size and hygroscopicity pairs. Moreover, those estimates were first compared with directly measured N CCN at the same site. Subsequently, N CCN was calculated using the same dataset but with an array of simplified treatments in which the aerosol was assumed to be either an internal or an external mixture and the hygroscopicity either assumed or based on averages derived from the growth factor distributions. The CCN spectra calculated using the simplified treatments were compared with those calculated using the baseline approach to evaluate the error introduced with commonly used approximations.

54 ENVIRONMENTAL SCIENCES↗

Consensus Modeling for Prediction of Estrogenic Activity of Ingredients Commonly Used in Sunscreen Products

Sunscreen products are predominantly regulated as over-the-counter (OTC) drugs by the US FDA. The “active” ingredients function as ultraviolet filters. Once a sunscreen product is generally recognized as safe and effective (GRASE) via an OTC drug review process, new formulations using these ingredients do not require FDA review and approval, however, the majority of ingredients have never been tested to uncover any potential endocrine activity and their ability to interact with the estrogen receptor (ER) is unknown, despite the fact that this is a very extensively studied target related to endocrine activity. Consequently, we have developed an in silico model to prioritize single ingredient estrogen receptor activity for use when actual animal data are inadequate, equivocal, or absent. It relies on consensus modeling to qualitatively and quantitatively predict ER binding activity. As proof of concept, the model was applied to ingredients commonly used in sunscreen products worldwide and a few reference chemicals. Of the 32 chemicals with unknown ER binding activity that were evaluated, seven were predicted to be active estrogenic compounds. Five of the seven were confirmed by the published data. Further experimental data is needed to confirm the other two predictions.

60 APPLIED LIFE SCIENCES↗

A Comparative Multi-System Approach to Characterizing Bioactivity of Commonly Occurring Chemicals

A 2019 retrospective study analyzed wristband personal samplers from fourteen different communities across three different continents for over 1530 organic chemicals. Investigators identified fourteen chemicals (G14) detected in over 50% of personal samplers. The G14 represent a group of chemicals that individuals are commonly exposed to, and are mainly associated with consumer products including plasticizers, fragrances, flame retardants, and pesticides. The high frequency of exposure to these chemicals raises questions of their potential adverse human health effects. Additionally, the possibility of exposure to mixtures of these chemicals is likely due to their co-occurrence; thus, the potential for mixtures to induce differential bioactivity warrants further investigation. This study describes a novel approach to broadly evaluate the hazards of personal chemical exposures by coupling data from personal sampling devices with high-throughput bioactivity screenings using in vitro and non-mammalian in vivo models. To account for species and sensitivity differences, screening was conducted using primary normal human bronchial epithelial (NHBE) cells and early life-stage zebrafish. Mixtures of the G14 and most potent G14 chemicals were created to assess potential mixture effects. Chemical bioactivity was dependent on the model system, with five and eleven chemicals deemed bioactive in NHBE and zebrafish, respectively, supporting the use of a multi-system approach for bioactivity testing and highlighting sensitivity differences between the models. In both NHBE and zebrafish, mixture effects were observed when screening mixtures of the most potent chemicals. Observations of BMC-based mixtures in NHBE (NHBE BMC Mix) and zebrafish (ZF BMC Mix) suggested antagonistic effects. In this study, consumer product-related chemicals were prioritized for bioactivity screening using personal exposure data. High-throughput high-content screening was utilized to assess the chemical bioactivity and mixture effects of the most potent chemicals.

60 APPLIED LIFE SCIENCES↗

Comparative Phenotyping of Two Commonly Used Chlamydomonas reinhardtii Background Strains: CC-1690 (21gr) and CC-5325 (The CLiP Mutant Library Background)

The unicellular green alga Chlamydomonas reinhardtii is an excellent model organism to investigate many essential cellular processes in photosynthetic eukaryotes. Two commonly used background strains of Chlamydomonas are CC-1690 and CC-5325. CC-1690, also called 21gr, has been used for the Chlamydomonas genome project and several transcriptome analyses. CC-5325 is the background strain for the Chlamydomonas Library Project (CLiP). Photosynthetic performance in CC-5325 has not been evaluated in comparison with CC-1690. Additionally, CC-5325 is often considered to be cell-wall deficient, although detailed analysis is missing. The circadian rhythms in CC-5325 are also unclear. To fill these knowledge gaps and facilitate the use of the CLiP mutant library for various screens, we performed phenotypic comparisons between CC-1690 and CC-5325. Our results showed that CC-5325 grew faster heterotrophically in dark and equally well in mixotrophic liquid medium as compared to CC-1690. CC-5325 had lower photosynthetic efficiency and was more heat-sensitive than CC-1690. Furthermore, CC-5325 had an intact cell wall which had comparable integrity to that in CC-1690 but appeared to have reduced thickness. Additionally, CC-5325 could perform phototaxis, but could not maintain a sustained circadian rhythm of phototaxis as CC1690 did. Finally, in comparison to CC-1690, CC-5325 had longer cilia in the medium with acetate but slower swimming speed in the medium without nitrogen and acetate. Our results will be useful for researchers in the Chlamydomonas community to choose suitable background strains for mutant analysis and employ the CLiP mutant library for genome-wide mutant screens under appropriate conditions, especially in the areas of photosynthesis, thermotolerance, cell wall, and circadian rhythms.

59 BASIC BIOLOGICAL SCIENCES↗

In Situ High Pressure Hydrogen Tribological Testing of Common Polymer Materials Used in the Hydrogen Delivery Infrastructure

High pressure hydrogen gas is known to adversely affect metallic components of compressors, valves, hoses, and actuators. However, relatively little is known about the effects of high pressure hydrogen on the polymer sealing and barrier materials also found within these components. More study is required in order to determine the compatibility of common polymer materials found in the components of the hydrogen fuel delivery infrastructure with high pressure hydrogen. As a result, it is important to consider the changes in physical properties such as friction and wear in situ while the polymer is exposed to high pressure hydrogen. In this protocol, we present a method for testing the friction and wear properties of ethylene propylene diene monomer (EPDM) elastomer samples in a 28 MPa high pressure hydrogen environment using a custom-built in situ pin-on-flat linear reciprocating tribometer. Representative results from this testing are presented which indicate that the coefficient of friction between the EPDM sample coupon and steel counter surface is increased in high pressure hydrogen as compared to the coefficient of friction similarly measured in ambient air.

hydrogen↗

Evolution of dwarf spheroidal satellites in the common surface-density dark halos

We investigate the growth histories of dark matter halos associated with dwarf satellites in Local Group galaxies and the resultant evolution of the baryonic component. Our model is based on the recently proposed property that the mean surface density of a dark halo inside a radius at maximum circular velocity V{sub max} is universal over a large range of V{sub max}. Given that a surface density of 20 M {sub ⊙} pc{sup −2} well explains dwarf satellites in the Milky Way and Andromeda, we find that the evolution of the dark halo in this common surface-density scale is characterized by the rapid increase of the halo mass assembled by the redshift z{sub TT} of the tidal truncation by its host halo, at early epochs of z{sub TT}≳6 or V{sub max}≲22 km s{sup −1}. This mass growth of the halo is slow at lower z{sub TT} or larger V{sub max}. Taking into account the baryon content in this dark halo evolution, under the influence of the ionizing background radiation, we find that the dwarf satellites are divided into roughly two families: those with V{sub max}≲22 km s{sup −1} having high star formation efficiency and those with larger V{sub max} having less efficient star formation. This semianalytical model is in agreement with the high-resolution numerical simulation for galaxy formation and with the observed star formation histories for Fornax and Leo II. This suggests that the evolution of a dark halo may play a key role in understanding star formation histories in dwarf satellites.

79 ASTRONOMY AND ASTROPHYSICS↗

Tatooine's future: the eccentric response of Kepler's circumbinary planets to common-envelope evolution of their host stars

Inspired by the recent Kepler discoveries of circumbinary planets orbiting nine close binary stars, we explore the fate of the former as the latter evolve off the main sequence. We combine binary star evolution models with dynamical simulations to study the orbital evolution of these planets as their hosts undergo common-envelope (CE) stages, losing in the process a tremendous amount of mass on dynamical timescales. Five of the systems experience at least one Roche-lobe overflow and CE stage (Kepler-1647 experiences three), and the binary stars either shrink to very short orbits or coalesce; two systems trigger a double-degenerate supernova explosion. Kepler’s circumbinary planets predominantly remain gravitationally bound at the end of the CE phase, migrate to larger orbits, and may gain significant eccentricity; their orbital expansion can be more than an order of magnitude and can occur over the course of a single planetary orbit. The orbits these planets can reach are qualitatively consistent with those of the currently known post-CE, eclipse-time variations circumbinary candidates. Our results also show that circumbinary planets can experience both modes of orbital expansion (adiabatic and nonadiabatic) if their host binaries undergo more than one CE stage; multiplanet circumbinary systems like Kepler-47 can experience both modes during the same CE stage. Additionally, unlike Mercury orbiting the Sun, a circumbinary planet with the same semimajor axis can survive the CE evolution of a close binary star with a total mass of 1 M{sub ⊙}.

79 ASTRONOMY AND ASTROPHYSICS↗

4.5 YEARS OF MULTI-WAVELENGTH OBSERVATIONS OF MRK 421 DURING THE ARGO-YBJ AND FERMI COMMON OPERATION TIME

We report on the extensive multi-wavelength observations of the blazar Markarian 421 (Mrk 421) covering radio to γ-rays, during the 4.5 year period of ARGO-YBJ and Fermi common operation time, from 2008 August to 2013 February. These long-term observations, extending over an energy range of 18 orders of magnitude, provide a unique chance to study the variable emission of Mrk 421. In particular, due to the ARGO-YBJ and Fermi data, the entire energy range from 100 MeV to 10 TeV is covered without any gap. In the observation period, Mrk 421 showed both low- and high-activity states at all wavebands. The correlations among flux variations in different wavebands were analyzed. The X-ray flux is clearly correlated with the TeV γ-ray flux, while the GeV γ-rays only show a partial correlation with the TeV γ-rays. Radio and UV fluxes seem to be weakly or not correlated with the X-ray and γ-ray fluxes. Seven large flares, including five X-ray flares and two GeV γ-ray flares with variable durations (3–58 days), and one X-ray outburst phase were identified and used to investigate the variation of the spectral energy distribution with respect to a relative quiescent phase. During the outburst phase and the seven flaring episodes, the peak energy in X-rays is observed to increase from sub-keV to a few keV. The TeV γ-ray flux increases up to 0.9–7.2 times the flux of the Crab Nebula. The behavior of GeV γ-rays is found to vary depending on the flare, a feature that leads us to classify flares into three groups according to the GeV flux variation. Finally, the one-zone synchrotron self-Compton model was adopted to describe the emission spectra. Two out of three groups can be satisfactorily described using injected electrons with a power-law spectral index around 2.2, as expected from relativistic diffuse shock acceleration, whereas the remaining group requires a harder injected spectrum. The underlying physical mechanisms responsible for different groups may be related to the acceleration process or to the environment properties.

79 ASTRONOMY AND ASTROPHYSICS↗