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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.
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This profile provides a snapshot of the energy landscape of Antigua and Barbuda, an independent nation in the Leeward Islands in the eastern Caribbean Sea. Antigua and Barbuda's base residential utility rates are approximately $0.15 U.S. dollars (USD) per kilowatt-hour (kWh) plus a variable fuel charge.
This profile provides a snapshot of the energy landscape of the Federated States of Micronesia (FSM), a sovereign nation and U.S.-associated state in the western Pacific Ocean. The FSM is made up of more than 600 islands, which presents a significant challenge of delivering electricity to people living on outer islands. The country is striving to overcome electricity access needs, reduce high energy costs, and ensure energy security. Currently, almost all of the electricity produced in Micronesia is dependent upon imported petroleum based fossil fuels, with some solar photovoltaic systems in operation.
This profile provides a snapshot of the energy landscape of the British Virgin Islands (BVI), one of three sets of the Virgin Island territories in an archipelago making up the northern portion of the Lesser Antilles.
This profile provides a snapshot of the energy landscape of the Commonwealth of Dominica, an island nation located southeast of Guadeloupe and northwest of Martinique in the Lesser Antilles.
This profile provides a snapshot of the energy profile of the Cayman Islands, a British Overseas Territory, encompasses 3 islands in the western Caribbean Sea. Grand Cayman, Cayman Brac, and Little Cayman.
This profile provides a snapshot of the energy landscape of Montserrat, a British overseas territory located in the northern half of the Lesser Antilles.
This profile provides a snapshot of the energy landscape of Martinique, an insular region of France located in the Lesser Antilles of the West Indies in the eastern Caribbean Sea.
This profile provides a snapshot of the energy landscape for Guyana, a country on the northern mainland of South America that is culturally tied to the Caribbean. In the Nationally Determined Contributions, Guyana has committed to develop a mix of wind, solar, biomass and hydro-power to supply both demand of the national grid and the energy requirements for towns and villages in Guyana’s hinterland. Guyana has set an ambitious target of achieving close to 100% renewable energy in the power sector by 2025.
This profile provides a snapshot of the energy landscape of Guadeloupe, an overseas region of France located in the eastern Caribbean Sea. Guadeloupe has set a target to achieve 100% energy independence by 2030. As of 2018, 21% of Guadeloupe's electricity was generated by renewable energy.
This profile provides a snapshot of the energy landscape of the northeast Caribbean island Saint Martin. The island is divided between two nations, France in the north (Saint-Martin) and the Netherlands in the south (Sint Maarten).
This profile provides a snapshot of the energy landscape of Grenada—a small island nation consisting of the island of Grenada and six smaller islands in the southeastern Caribbean Sea—three of which are inhabited: Grenada, Carriacou, and Petite Martinique.
This profile provides a snapshot of the energy landscape of Aruba, an autonomous member of the Kingdom of the Netherlands located off the coast of Venezuela.
This profile provides a snapshot of the energy landscape of Trinidad and Tobago, a two-island nation located off the coast of Venezuela. Trinidad and Tobago's electricity rates are some of the lowest in the Caribbean at approximately $0.05 per kilowatt-hour (kWh), well below the regional average of $0.34/kWh.
This profile provides a snapshot of the energy landscape of Guadeloupe, an overseas region of France located in the eastern Caribbean Sea. Guadeloupe has set a target to achieve 100% energy independence by 2030. As of 2018, 21% of Guadeloupe's electricity was generated by renewable energy.
Serotonin (5-hydroxytryptamine [5-HT]) 5-HT2-family receptors represent essential targets for lysergic acid diethylamide (LSD) and all other psychedelic drugs. Although the primary psychedelic drug effects are mediated by the 5-HT 2A serotonin receptor (HTR2A), the 5-HT 2B serotonin receptor (HTR2B) has been used as a model receptor to study the activation mechanisms of psychedelic drugs due to its high expression and similarity to HTR2A. Here, in this study, we determined the cryo-EM structures of LSD-bound HTR2B in the transducer-free, Gq-protein-coupled, and β-arrestin-1-coupled states. These structures provide distinct signaling snapshots of LSD’s action, ranging from the transducer-free, partially active state to the transducer-coupled, fully active states. Insights from this study will both provide comprehensive molecular insights into the signaling mechanisms of the prototypical psychedelic LSD and accelerate the discovery of novel psychedelic drugs.
Reactions of lanthanide(III) chloride salts with 4-amino-1,2,4-triazole (4-NH 2 -1,2,4-Triaz) in azole melts have led to the isolation of both hydrolysis and non-hydrolysis products in the same synthesis with the inclusion of a variety of ligands, anions, and water, allowing us to capture crystallographic snapshots of different forms and intermediate hydrolysis fragments. The structural studies reported here include anhydrous and hydrated nonhydrolyzed complexes which were isolated alongside hydrolysis products giving oxide/hydroxide lanthanide(III) dimers, tetramers, and ultimately hexamers. The compounds isolated include [Nd 2 Cl 6 (μ 2 -4-NH 2 -1,2,4-Triaz) 4 (4-NH 2 -1,2,4-Triaz) 2 ], [Ce 2 Cl 4 (μ 2 -Cl) 2 (μ 2 -4-NH 2 -1,2,4-Triaz) 4 ] n , [Ce 2 (µ 2 -Cl) 4 (µ 2 -OH) 2 (µ 2 -4-NH 2 -1,2,4-Triaz) 2 ] n , [Ln 4 Cl 4 (µ 2 -Cl) 4 (µ 3 -OH) 4 (µ 2 -4-NH 2 -1,2,4-Triaz) 4 ] n •2nH 2 O (Ln = Ce, Nd), and [Ce 6 Cl 6 (µ 6 -O 0.5 )(µ 3 -Cl 0.5 ) 4 (µ 3 -Cl 0.75 ) 3 (µ 3 -OH) 0.75 (µ 2 -4-NH 2 -1,2,4-Triaz) 12 ((OH 2 ) 0.25 ) 2 ] 2 [CeCl 6 ][Cl 9 ]•xH 2 O. In all complexes all lanthanide atoms are pairwise connected via one or more 4-NH2-1,2,4-Triaz ligands and sometimes additional Cl - anions.
Abstract Multispectral imaging has been used for numerous applications in e.g., environmental monitoring, aerospace, defense, and biomedicine. Here, we present a diffractive optical network-based multispectral imaging system trained using deep learning to create a virtual spectral filter array at the output image field-of-view. This diffractive multispectral imager performs spatially-coherent imaging over a large spectrum, and at the same time, routes a pre-determined set of spectral channels onto an array of pixels at the output plane, converting a monochrome focal-plane array or image sensor into a multispectral imaging device without any spectral filters or image recovery algorithms. Furthermore, the spectral responsivity of this diffractive multispectral imager is not sensitive to input polarization states. Through numerical simulations, we present different diffractive network designs that achieve snapshot multispectral imaging with 4, 9 and 16 unique spectral bands within the visible spectrum, based on passive spatially-structured diffractive surfaces, with a compact design that axially spans ~72 λ m , where λ m is the mean wavelength of the spectral band of interest. Moreover, we experimentally demonstrate a diffractive multispectral imager based on a 3D-printed diffractive network that creates at its output image plane a spatially repeating virtual spectral filter array with 2 × 2 = 4 unique bands at terahertz spectrum. Due to their compact form factor and computation-free, power-efficient and polarization-insensitive forward operation, diffractive multispectral imagers can be transformative for various imaging and sensing applications and be used at different parts of the electromagnetic spectrum where high-density and wide-area multispectral pixel arrays are not widely available.
Abstract A primary reason for the intense interest in structural biology is the fact that knowledge of structure can elucidate macromolecular functions in living organisms. Sustained effort has resulted in an impressive arsenal of tools for determining the static structures. But under physiological conditions, macromolecules undergo continuous conformational changes, a subset of which are functionally important. Techniques for capturing the continuous conformational changes underlying function are essential for further progress. Here, we present chemically-detailed conformational movies of biological function, extracted data-analytically from experimental single-particle cryo-electron microscopy (cryo-EM) snapshots of ryanodine receptor type 1 (RyR1), a calcium-activated calcium channel engaged in the binding of ligands. The functional motions differ substantially from those inferred from static structures in the nature of conformationally active structural domains, the sequence and extent of conformational motions, and the way allosteric signals are transduced within and between domains. Our approach highlights the importance of combining experiment, advanced data analysis, and molecular simulations.