Controlled freezing of biological samples
Apparatus consists of thermocouple connected to semiconductor reference junction. Junction is connected to amplifier that boosts signal by 1,000. High-level signal is displayed on recorder and fed into second amplifier where it is compared with signal from potentiometer of programmed dc reference in bag-temperature programer. Difference in signals indicates output voltage. Remaining circuitry provides zero-phase, time-proportion control of heaters such that heater power is directly proportional to error signal.