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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 55 records · Page 3
All sourcesNASA NTRSDOE OSTI
DOE OSTI2025

Cryogenic Testing of HL-LHC Q1/Q3 Cryo-Assemblies at Fermilab

Fermilab is conducting horizontal cryogenic testing of Q1/Q3 Cryo-Assemblies for the high-luminosity LHC upgrade (HL-LHC). Cryo-Assemblies are installed on the upgraded Fermilab horizontal test stand previously used for testing the LHC inner triplet quadrupoles. The cryogenic process requirements of these tests include controlled cool-down and warm-up with a 100 K maximum temperature differential between the two ends of the cold mass, operation of a 1.3 bar, 1.9 K bath of subcooled superfluid helium during power testing and magnetic measurements, and operation at pressures up to 18 bar with full helium recovery after a quench. This paper presents the operational experience gained from the first tests as well as improvements for subsequent tests.

Rabehl, R. [Fermilab]↗
DOE OSTI2026

US HL-LHC cryo-assemblies at FNAL - testing and lessons learned

The U.S. High-Luminosity LHC Accelerator Upgrade Project (AUP) is fabricating ten cryogenic assemblies for the HL-LHC Q1/Q3 quadrupole optics at CERN, each integrating two Nb_{3}Sn-based magnets. Fermilab has tested three assemblies (LQXFA/B01–03) at its upgraded horizontal test stand under 1.9 K conditions. Overview of the test stand and the cryo-assembly tests is given along with main results. Challenges met and lessons learned are discussed. Successful testing validates the design and integration of U.S.-produced cryo-assemblies, keeping the project on track for timely delivery to CERN.

Stoynev, Stoyan [Fermilab] (ORCID:0000000345637702↗
NASA NTRS2003

Finding the Cold Needle in a Warm Haystack: Infrared Imaging Applied to Locating Cryo-cooled Crystals in Loops

Thermally imaging the cryocooling processes of crystals has been demonstrated showing the progression of a cold wave through a crystal from the face closest to the origin of the coldstream ending at the point furthest away. During these studies large volume crystals were clearly distinguished from the loop holding them. Large volume crystals, used for neutron studies, were chosen deliberately to enhance the imaging. The different infrared transmission and reflectance properties of the crystal in comparison to the cryo-protectant are thought to be the parameter that produces the contrast making the crystal visible. As an application of the technology to locating crystals, more small crystals of lysozyme and a bFGF/dna complex were cryo-protected and imaged in large loops. The crystals were clearly distinguished from the vitrified solution. In the case of the bFGF/dna complex the illumination had to be carefully manipulated to enable the crystal to be seen in the visible spectrum. These preliminary results will be presented along with advantages and disadvantages of the technique and a discussion of how it might be applied.

Snell, Edward↗
NASA NTRS2015

JWST Pathfinder Telescope Risk Reduction Cryo Test Program

In 2014, the Optical Ground Support Equipment was integrated into the large cryo vacuum chamber at Johnson Space Center (JSC) and an initial Chamber Commissioning Test was completed. This insured that the support equipment was ready for the three Pathfinder telescope cryo tests. The Pathfinder telescope which consists of two primary mirror segment assemblies and the secondary mirror was delivered to JSC in February 2015 in support of this critical risk reduction test program prior to the flight hardware. This paper will detail the Chamber Commissioning and first optical test of the JWST Pathfinder telescope.

Integration↗
NASA NTRS2018

Thermal Model Performance for the James Webb Space Telescope OTIS Cryo-Vacuum Test

The James Webb Space Telescope (JWST), set to launch in mid-2020, is currently undergoing a series of system-level environmental tests to verify its workmanship and end-to-end functionality. As part of this series, the Optical Telescope Element and Integrated Science Instrument Module (OTIS) Cryo-Vacuum (CV) test, the most complex cryogenic test executed to date by NASA, has recently been completed at the Johnson Space Center's Chamber A facility. The OTIS CV test was intended as a comprehensive test of the integrated instrument and telescope systems to fully understand its optical, structural, and thermal performance within its intended flight environment. Due to its complexity, extensive pre-test planning was required to ensure payload safety and compliance with all limits and constraints. A system-level pre-test thermal model was constructed which fully captured the behavior of the payload, ground support equipment, and surrounding test chamber. This thermal model simulated both the transient cooldown to and warmup from a 20 K flight-like environment, as well as predicted the payload performance at cryo-stable conditions. The current work is an assessment of thermal model pre-test prediction performance against actual payload response during the OTIS CV test. Overall, the thermal model performed exceedingly well at predicting schedule and payload response. Looking in depth, this work examines both the benefits and shortcomings of assumptions made pre-test to simplify model execution when compared against test data. It explores in detail the role of temperature-dependent emissivities during transition to cryogenic temperatures, as well as the impact that model geometry simplifications have on tracking of critical hardware limits and constraints. This work concludes with a list of recommendations to improve the accuracy of thermal modeling for future large cryogenic tests. The insight gained from the OTIS CV test thermal modeling will benefit planning and execution for upcoming cryogenic missions.

Testing↗
NASA NTRS2018

Thermal Model Performance for the James Webb Space Telescope OTIS Cryo-Vacuum Test

The James Webb Space Telescope (JWST), set to launch in early 2019, is currently undergoing a series of system-level environmental tests to verify its workmanship and end-to-end functionality. As part of this series, the Optical Telescope Element and Integrated Science Instrument Module (OTIS) Cryo-Vacuum (CV) test, the most complex cryogenic test executed to date by NASA, has recently been completed at the Johnson Space Center's Chamber A facility. The OTIS CV test was intended as a comprehensive test of the integrated instrument and telescope systems to fully understand its optical, structural, and thermal performance within its intended flight environment. Due to its complexity, extensive pre-test planning was required to ensure payload safety and compliance with all limits and constraints. A system-level pre-test thermal model was constructed which fully captured the behavior of the payload, ground support equipment, and surrounding test chamber. This thermal model simulated both the transient cooldown to and warmup from a 20K flight-like environment, as well as predicted the payload performance at cryo-stable conditions. The current work is a preliminary assessment of thermal model performance against actual payload response during the OTIS CV test. It examines both the benefits and shortcomings of assumptions made pre-test to simplify model execution when compared against test data. It explores in detail the role of temperature-dependent emissivities during transition to cryogenic temperatures, as well as the impact that model geometry simplifications have on tracking of critical hardware limits and constraints. This work concludes with a list of recommendations to improve the accuracy of thermal modeling for future large cryogenic tests. It is hoped that the insight gained from the OTIS CV test thermal modeling will benefit planning and execution for upcoming cryogenic missions.

JWST↗
NASA NTRS2018

Thermal Model Performance for the James Webb Space Telescope OTIS Cryo-Vacuum Test

The James Webb Space Telescope (JWST), set to launch in early 2019, is currently undergoing a series of system-level environmental tests to verify its workmanship and end-to-end functionality. As part of this series, the Optical Telescope Element and Integrated Science Instrument Module (OTIS) Cryo-Vacuum (CV) test, the most complex cryogenic test executed to date by NASA, has recently been completed at the Johnson Space Center’s Chamber A facility. The OTIS CV test was intended as a comprehensive test of the integrated instrument and telescope systems to fully understand its optical, structural, and thermal performance within its intended flight environment. Due to its complexity, extensive pre-test planning was required to ensure payload safety and compliance with all limits and constraints. A system-level pre-test thermal model was constructed which fully captured the behavior of the payload, ground support equipment, and surrounding test chamber. This thermal model simulated both the transient cooldown to and warmup from a 20K flight-like environment, as well as predicted the payload performance at cryo-stable conditions. The current work is a preliminary assessment of thermal model performance against actual payload response during the OTIS CV test. Overall, the thermal model performed exceedingly well at predicting schedule and payload response. Looking in depth, this work examines both the benefits and shortcomings of assumptions made pre-test to simplify model execution when compared against test data. It explores in detail the role of temperature-dependent emissivities during transition to cryogenic temperatures, as well as the impact that model geometry simplifications have on tracking of critical hardware limits and constraints. This work concludes with a list of recommendations to improve the accuracy of thermal modeling for future large cryogenic tests. It is hoped that the insight gained from the OTIS CV test thermal modeling will benefit planning and execution for upcoming cryogenic missions.

Yang, Kan↗
DOE OSTI2025

Cryogenic testing of HL-LHC Q1/Q3 cryo-assemblies at Fermilab

Fermilab is conducting horizontal cryogenic testing of Q1/Q3 cryo-assemblies for the high-luminosity LHC upgrade (HL-LHC). Cryo-assemblies are installed on the upgraded Fermilab horizontal test stand previously used for testing the LHC inner triplet quadrupoles. The cryogenic process requirements of these tests include controlled cool-down and warm-up with a 100 K maximum temperature differential between the two ends of the cold mass, operation of a 1.3 bar, 1.9 K bath of subcooled superfluid helium during power testing and magnetic measurements, and operation at pressure up to 18 bar with full helium recovery after a quench. This paper presents the operational experience gained from the first tests as well as improvement for subsequent tests.

Rabehl, R. [Fermilab] (ORCID:0000000311130030)↗
DOE OSTI2024

First operation and validation of simulations for the divertor cryo-vacuum pump in Wendelstein 7-X

Ten cryo-vacuum pumps (CVPs) were installed in the subdivertor region of each island divertor in the stellarator Wendelstein 7-X (W7-X) and operated for the first time during the recently completed plasma campaign OP2.1. A pumping speed of 70 ± 1 $\frac{m^3}{s}$ was measured during dedicated tests with known hydrogen gas injection. Based on a conductance model, the estimated pumping speed ranges from 86-93 $\frac{m^3}{s}$ for different sticking coefficients between 0.6 and 0.8. After completion of the initial tests the CVPs were operated successfully throughout the campaign, with regeneration performed once a week. Neutral gas pressures in the subdivertor in the range of 10 −4 mbar are well within the molecular flow regime and limit the particle exhaust capabilities of the CVPs. Simulations of the neutral gas pressure in the three-dimensional complex geometry of the subdivertor were performed using the DIVGAS code based on the direct simulation Monte Carlo method and a model implemented in the steady-state thermal package in ANSYS, which are in agreement with the measured values during plasma operation.

Cryo-vacuum pumping↗
DOE OSTI2024

Angle between DNA linker and nucleosome core particle regulates array compaction revealed by individual-particle cryo-electron tomography

Abstract The conformational dynamics of nucleosome arrays generate a diverse spectrum of microscopic states, posing challenges to their structural determination. Leveraging cryogenic electron tomography (cryo-ET), we determine the three-dimensional (3D) structures of individual mononucleosomes and arrays comprising di-, tri-, and tetranucleosomes. By slowing the rate of condensation through a reduction in ionic strength, we probe the intra-array structural transitions that precede inter-array interactions and liquid droplet formation. Under these conditions, the arrays exhibite irregular zig-zag conformations with loose packing. Increasing the ionic strength promoted intra-array compaction, yet we do not observe the previously reported regular 30-nanometer fibers. Interestingly, the presence of H1 do not induce array compaction; instead, one-third of the arrays display nucleosomes invaded by foreign DNA, suggesting an alternative role for H1 in chromatin network construction. We also find that the crucial parameter determining the structure adopted by chromatin arrays is the angle between the entry and exit of the DNA and the corresponding tangents to the nucleosomal disc. Our results provide insights into the initial stages of intra-array compaction, a critical precursor to condensation in the regulation of chromatin organization.

59 BASIC BIOLOGICAL SCIENCES↗
DOE OSTI2026

Two datasets are better than one: method of double moments for 3D reconstruction in cryo-EM

Cryo-electron microscopy is a powerful imaging technique for reconstructing three-dimensional molecular structures from noisy tomographic projection images of randomly oriented particles. We introduce a new data fusion framework, termed the method of double moments, which reconstructs molecular structures from two instances of the second-order moment of projection images obtained under distinct orientation distributions: one uniform, the other non-uniform and unknown. We prove that these moments generically uniquely determine the underlying structure, up to a global rotation and reflection, and we develop a convex-relaxation-based algorithm that achieves accurate recovery using only second-order statistics. Our results demonstrate the advantage of collecting and modeling multiple datasets under different experimental conditions, illustrating that leveraging dataset diversity can substantially enhance reconstruction quality in computational imaging tasks.

Kam’s method↗
DOE OSTI2024

Likelihood-based interactive local docking into cryo-EM maps in ChimeraX

The interpretation of cryo-EM maps often includes the docking of known or predicted structures of the components, which is particularly useful when the map resolution is worse than 4 Å. Although it can be effective to search the entire map to find the best placement of a component, the process can be slow when the maps are large. However, frequently there is a well-founded hypothesis about where particular components are located. In such cases, a local search using a map subvolume will be much faster because the search volume is smaller, and more sensitive because optimizing the search volume for the rotation-search step enhances the signal to noise. A Fourier-space likelihood-based local search approach, based on the previously published em_placement software, has been implemented in the new emplace_local program. Tests confirm that the local search approach enhances the speed and sensitivity of the computations. An interactive graphical interface in the ChimeraX molecular-graphics program provides a convenient way to set up and evaluate docking calculations, particularly in defining the part of the map into which the components should be placed.

59 BASIC BIOLOGICAL SCIENCES↗
NASA NTRS2014

James Webb Space Telescope (JWST) Integrated Science Instruments Module (ISIM) Cryo-Vacuum (CV) Test at GSFC

JWST ISIM has entered into its system-level testing program at NASA Goddard Space Flight Center (GSFC). In December 2013, ISIM successfully completed the first in a series of three cryo-vacuum tests, which included two flight science instruments. Since then, there have been full-fledged efforts towards the CV2 test scheduled to finish at the end of 2014. The complexity of the mission has generated challenging requirements that demand highly reliable system performance and capabilities from the Space Environment Simulator (SES) vacuum chamber. In order to satisfy the program requirements, GSFC had to develop unique structural and thermal hardware to test ISIM. Most noteworthy is a helium shroud structure and cooling system built in order to achieve operational temperatures below 20K (-253C). This paper: (1) provides an overview of the integrated mechanical and thermal facility systems required to achieve the objectives of JWST ISIM testing, (2) communicates the performance and challenges of the SES during the first ISIM test, and (3) summarizes the action plan to improve the system prior to the next test.

Thermal Vacuum Cryo Testing Chamber↗
NASA NTRS2017

Thermal Considerations for Reducing the Cooldown and Warmup Duration of the James Webb Space Telescope OTIS Cryo-Vacuum Test

The James Webb Space Telescope (JWST), set to launch in 2018, is NASAs next-generation flagship telescope. The Optical Telescope Element (OTE) and Integrated Science Instrument Module (ISIM) contain all of the optical surfaces and instruments to capture and analyze the telescopes infrared targets. The integrated OTE and ISIM are denoted as OTIS, and will be tested as a single unit in a critical thermal-vacuum test in mid-2017 at NASA Johnson Space Centers Chamber A facility. The payload will be evaluated for workmanship and functionality in a 20K simulated flight environment during this thermal-vacuum test. However, the sheer thermal mass of the OTIS payload as well as the restrictive gradient, rate, and contamination-related constraints placed on test components precludes rapid cooldown or warmup to its steady-state cryo-balance condition. Hardware safety considerations precludes injection of helium gas for free molecular heat transfer. Initial thermal analysis predicted that transient radiative cooldown from ambient temperatures, while meeting all limits and constraints, would take 33.3 days; warmup similarly would take 28.4 days. This paper discusses methods used to reduce transition times from the original predictions through modulation of boundary temperatures and environmental conditions. By optimizing helium shroud transition rates and heater usage, as well as rigorously re-examining previously imposed constraints, savings of up to three days on cooldown and up to a week on warmup can be achieved. The efficiencies gained through these methods allow the JWST thermal test team to create faster cooldown and warmup profiles, thus reducing the overall test duration and cost, while keeping all of the required test operations.

Thermal↗
NASA NTRS2017

Thermal Considerations for Reducing the Cooldown and Warmup Duration of the James Webb Space Telescope OTIS Cryo-Vacuum Test

The James Webb Space Telescope (JWST), set to launch in 2018, is NASAs next-generation flagship telescope. The Optical Telescope Element (OTE) and Integrated Science Instrument Module (ISIM) contain all of the optical surfaces and instruments to capture and analyze the telescopes infrared targets. The integrated OTE and ISIM are denoted as OTIS, and will be tested as a single unit in a critical thermal-vacuum test in mid-2017 at NASA Johnson Space Centers Chamber A facility. The payload will be evaluated for workmanship and functionality in a 20K simulated flight environment during this thermal-vacuum test. However, the sheer thermal mass of the OTIS payload as well as the restrictive gradient, rate, and contamination-related constraints placed on test components precludes rapid cooldown or warmup to its steady-state cryo-balance condition. Hardware safety considerations precludes injection of helium gas for free molecular heat transfer. Initial thermal analysis predicted that transient radiative cooldown from ambient temperatures, while meeting all limits and constraints, would take 33.3 days; warmup similarly would take 28.4 days. This paper discusses methods used to reduce transition times from the original predictions through modulation of boundary temperatures and environmental conditions. By optimizing helium shroud transition rates and heater usage, as well as rigorously re-examining previously imposed constraints, savings of up to three days on cooldown and up to a week on warmup can be achieved. The efficiencies gained through these methods allow the JWST thermal test team to create faster cooldown and warmup profiles, thus reducing the overall test duration and cost, while keeping all of the required test operations.

JWST↗
NASA NTRS1995

Lessons Learned From the Flight of the NASA In-Step Cryo System Experiment

The Cryo System Experiment (CSE), a NASA In-Space Technology Experiments Program (IN- STEP) Flight Experiment, was developed by Hughes Aircraft Company under contract to the Jet Propulsion Laboratory (JPL) to validate in near zero-g space a 65 K cryogenic system for focal planes, optics, instruments, or other equipment (gamma-ray spectrometers, and infrared and submillimeter imaging instruments) that require continuous cryogenic cooling.

NASA↗
DOE OSTI2026

Cryo-electron microscopy structure of a zinc uptake ABC transporter

Zn2+ is an essential micronutrient required for many biological processes. Microorganisms employ high-affinity Zn2+ ABC transporters to take up zinc from the environment when it is scarce, yet the mechanism of zinc uptake and its regulation remain poorly understood. Here, we report the cryo-electron microscopy structure of the Zn2+ ABC transporter complex ZnuB-ZnuC from Escherichia coli. It contains two ZnuB transport and two ZnuC regulatory subunits. The ZnuB homodimer is in an outward-facing, closed conformation with a large hydrophilic cavity at the dimer interface. Each ZnuC subunit contains an N-terminal nucleotide-binding domain and a C-terminal zinc-sensing domain (ZSD). Zn2+ binding to the ZSD locks the transporter in a closed state, whereas under low-Zn2+ conditions, the disorder of ZSD permits ATP-driven zinc uptake. Zn2+ ABC transporters are ubiquitously utilized by pathogenic bacteria to compete with hosts for Zn2+. These findings reveal potential therapeutic targets for disrupting Zn2+ homeostasis in antibiotic-resistant pathogens.

59 BASIC BIOLOGICAL SCIENCES↗
DOE OSTI2026

Optimizing Cryo-Focused Pyrolysis GC/MS for Tracing Soil Organic Matter Across Diverse Ecosystems

The cycling of organic matter in terrestrial soils and sediments is central to a range of biogeochemical processes that regulate nutrient cycling, crop productivity, trace gas emissions, and contaminant transport. Pyrolysis-gas chromatography/mass spectrometry (py-GC/MS) is a powerful tool for characterizing bulk soil organic matter (SOM) at the molecular level. In this study, we used a cryo-focused py-GC/MS system to analyze soil samples from seven diverse ecosystems: vernal pool, prairie pothole, temperate forest, tropical forest, tundra, wildfire-affected boreal forest, and grassland. We addressed a key bottleneck in molecular-level SOM characterization by developing an automated data analysis pipeline to optimize py-GC/MS and complementary evolved gas analysis/mass spectrometry (EGA/MS) methods, incorporating advanced tools for peak deconvolution, developing a custom compound class library, and implementing fragmentation spectrum-based molecular networking for the first time. This improved workflow was applied to soil samples from all seven ecosystems, including multiple depths and density fractions. Our findings demonstrate that ecosystem type plays a dominant role in shaping compositional differences in SOM. We also identified trends in the source of SOM compounds (e.g., microbial vs plantderived) across soil depth and density fractions, which are critical for understanding persistence and turnover of SOM. Our molecular networking analysis indicated that although many compounds are widespread across ecosystems, others are restricted to specific environments, such as wetlands. This underscores the utility of molecular-level data in elucidating the complexity of SOM composition and the environmental drivers that shape it. Such molecular-level insights can deepen our knowledge of biogeochemical SOM cycles.

54 ENVIRONMENTAL SCIENCES↗