Nuclear magnetic resonance of phosphorus in deoxythmidine polynucleotides.
Terminal monoester and diester phosphate of deoxythymidine polynucleotide identified by nuclear magnetic resonance
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Terminal monoester and diester phosphate of deoxythymidine polynucleotide identified by nuclear magnetic resonance
Geminal and vicinal proton-proton couplings - nuclear magnetic resonance spin-spin coupling
Apollo 11 rock and fines magnetic resonance, examining line shapes, temperature dependences and electron spin
Chondritic meteorites electron and nuclear magnetic resonance spectra at various frequencies
We apply the magnetic resonance sounding (MRS) method to investigate a firn aquifer in the south-east region of the Greenland ice sheet. Our study aims to delineate and estimate the volume of the recently discovered water stored within the firn (compacted snow) that remains liquid throughout the year. We develop and test successfully amethodology for joint use of MRS and ground-penetrating radar (GPR). This noninvasive geophysical approach is particularly well-adapted to glacier conditions and has a promising future for in situ investigation of water distribution in glaciers. At our field site, MRS showed an aquifer located at variable depths between 20 and 30 m beneath the ice-sheet surface. At the monitoring site, both MRS and GPR show an increase in the water volume stored between April 2015 and July 2016. MRS estimates suggest that the volume increased by approximately 28%.
The Mars lander missions will involve in-situ sample analysis techniques and we are proposing the Magnetic Resonance Spectroscopy to obtain much needed martian surface chemical information.
Nuclear magnetic resonance of phosphorus compounds, discussing signs of spin-spin couplings in dimethylphosphine and methylphosphine
Gas-liquid and thin layer chromatography and nuclear magnetic resonance techniques to steric analysis of diketopiperazines
System calibrates and records the responses of a nuclear magnetic resonance spectrometer. Calibration markers which have a highly stable frequency source are utilized to maintain frequency stability.
Ground-based investigations of a new biomedical diagnostic technology: nuclear magnetic resonance of laser polarized noble gas are addressed. The specific research tasks discussed are: (1) Development of a large-scale noble gas polarization system; (2) biomedical investigations using laser polarized noble gas in conventional (high magnetic field) NMR systems; and (3) the development and application of a low magnetic field system for laser polarized noble gas NMR.
Nuclear magnetic resonance (NMR) is a powerful and versatile, noninvasive method for studying fluid transport problems, However, its applications to these types of investigations have been limited. A primary factor that limits the application of NMR has been the lack of a user-friendly, versatile, and inexpensive NMR imaging apparatus that can be used by scientists who are not familiar with sophisticated NMR. To rectify this situation, we developed a user-friendly, NMR imager for projects of relevance to the MRD science community. To that end, we performed preliminary collaborative experiments between NASA, NCMR, and New Mexico Resonance in the high field NMR set up at New Mexico Resonance to track wetting front dynamics in foams under gravity. The experiments were done in a 30 cm, 1.9T Oxford magnet with a TECMAG Libra spectrometer (Tecmag, Inc., Houston, TX). We used two different imaging strategies depending on whether the water in the foam sample was static or moving. Stationary water distributions were imaged with the standard Fourier imaging method, as used in medical MRI, in which data are acquired from all parts of the region of interest at all times and Fourier transformed into a static spatial image.
A high-resolution magnetic resonance imaging (MRI) protocol, together with specialized image processing techniques, was applied to the quantitative measurement of age-related changes in calcaneal trabecular structure. The reproducibility of the technique was assessed and the annual rates of change for several trabecular structure parameters were measured. The MR-derived trabecular parameters were compared with calcaneal bone mineral density (BMD), measured by dual X-ray absorptiometry (DXA) in the same subjects. Sagittal MR images were acquired at 1.5 T in 23 healthy women (mean age: 49.3 +/- 16.6 [SD]), using a three-dimensional gradient echo sequence. Image analysis procedures included internal gray-scale calibration, bone and marrow segmentation, and run-length methods. Three trabecular structure parameters, apparent bone volume (ABV/TV), intercept thickness (I.Th), and intercept separation (I.Sp) were calculated from the MR images. The short- and long-term precision errors (mean %CV) of these measured parameters were in the ranges 1-2% and 3-6%, respectively. Linear regression of the trabecular structure parameters vs. age showed significant correlation: ABV/TV (r2 = 33.7%, P < 0.0037), I.Th (r2 = 26.6%, P < 0.0118), I.Sp (r2 = 28.9%, P < 0.0081). These trends with age were also expressed as annual rates of change: ABV/TV (-0.52%/year), I.Th (-0.33%/year), and I.Sp (0.59%/year). Linear regression analysis also showed significant correlation between the MR-derived trabecular structure parameters and calcaneal BMD values. Although a larger group of subjects is needed to better define the age-related changes in trabecular structure parameters and their relation to BMD, these preliminary results demonstrate that high-resolution MRI may potentially be useful for the quantitative assessment of trabecular structure.
Cis- and trans-beta-bromostyrene reaction with lithium diphenylphosphide in tetrahydrofuran producing cis- and trans-beta- styryldiphenylphosphine, discussing proton magnetic resonance and configuration retention
Precise sweep calibrations and simultaneous spectrum recording for high resolution nuclear magnetic resonance spectroscopy
Apollo 12 lunar soil samples magnetic resonance properties, determining temperature, frequency and thermal annealing dependence
A new method for analyzing the kinematics of joint motion using magnetic resonance imaging (MRI) is described. The reconstruction of the metacarpalphalangeal joint of the left index finger into a 3D graphic display is shown. From the reconstructed volumetric images, measurements of the angles of movement of the applicable bones are obtained and processed by analyzing the screw motion of the joint. Landmark positions are chosen at distinctive locations of the joint at fixed image threshold intensity levels to ensure repeatability. The primarily 2D planar motion of this joint is then studied using a method of constructing coordinate systems using three or more points. A transformation matrix based on a world coordinate system describes the location and orientation of the local target coordinate system. The findings show the applicability of MRI to joint kinematics for gaining further knowledge of the hand-glove design for EVA.
Nuclear magnetic resonance spectrometer for moisture content measurement of lunar and terrestrial soils and rocks
It is proposed that in a nuclear magnetic resonance (NMR) imaging experiment that it should be possible to measure temperature through an extended volume. The basis for such a measurement would depend upon sensing a temperature dependent on NMR parameter in an inert, volatile molecule (or fluid) filling the volume of interest. Exploratory work suggest that one suitable candidate for such a purpose might be CH3Cl. Possible parameters, other inert gases and feasible measurement schemes that might provide such temperature measurement are discussed.