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At least 55 records · Page 3

The genomic effects of cell phone exposure on the reproductive system

Highlights: • Electromagnetic fields (EMF) causes an imbalance between pro-oxidant and antioxidant mechanismsEMF increases reactive oxygen species production. • Exposure to EMF leads to disruptions in spermatogenic cells. • Exposure to GSM-modulated EMF causes an increase in superoxide formation levels in human spermatozoa. Humans are exposed to increasing levels of electromagnetic fields (EMF) at various frequencies as technology advances. In this context, improving understanding of the biological effects of EMF remains an important, high priority issue. Although a number of studies in this issue and elsewhere have focused on the mechanisms of the oxidative stress caused by EMF, the precise understanding of the processes involved remains to be elucidated. Due to unclear results among the studies, the issue of EMF exposure in the literature should be evaluated at the genomic level on the reproductive system. Based on this requirement, a detail review of recently published studies is necessary. The main objectives of this study are to show differences between negative and positive effect of EMF on the reproductive system of animal and human. Extensive review of literature has been made based on well known data bases like Web of Science, PubMed, MEDLINE, Google Scholar, Science Direct, Scopus. This paper reviews the current literature and is intended to contribute to a better understanding of the genotoxic effects of EMF emitted from mobile phones and wireless systems on the human reproductive system, especially on fertility. The current literature reveals that mobile phones can affect cellular functions via non-thermal effects. Although the cellular targets of global system for mobile communications (GSM)-modulated EMF are associated with the cell membrane, the subject is still controversial. Studies regarding the genotoxic effects of EMF have generally focused on DNA damage. Possible mechanisms are related to ROS formation due to oxidative stress. EMF increases ROS production by enhancing the activity of nicotinamide adenine dinucleotide (NADH) oxidase in the cell membrane. Further detailed studies are needed to elucidate DNA damage mechanisms and apoptotic pathways during oogenesis and spermatogenesis in germ cells exposed to EMF.

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTAN↗

Development of structural health monitoring and early warning system for reinforced concrete system

Many buildings have been damaged due to earthquakes that occurred recently in Indonesia. The main cause of the damage is the large deformation of the building structural component cannot accommodate properly. Therefore, it is necessary to develop the Structural Health Monitoring System (SHMS) to measure precisely the deformation of the building structural component in the real time conditions. This paper presents the development of SHMS for reinforced concrete structural system. This monitoring system is based on deformation component such as strain of reinforcement bar, concrete strain, and displacement of reinforced concrete component. Since the deformation component has exceeded the limit value, the warning message can be sent to the building occupies. This warning message has also can be performed as early warning system of the reinforced concrete structural system. The warning message can also be sent via Short Message Service (SMS) through the Global System for Mobile Communications (GSM) network. Hence, the SHMS should be integrated with internet modem to connect with GSM network. Additionally, the SHMS program is verified with experimental study of simply supported reinforced concrete beam. Verification results show that the SHMS has good agreement with experimental results.

42 ENGINEERING↗

A statistical study of gyro-averaging effects in a reduced model of drift-wave transport

Here, a statistical study of finite Larmor radius (FLR) effects on transport driven by electrostatic driftwaves is presented. The study is based on a reduced discrete Hamiltonian dynamical system known as the gyro-averaged standard map (GSM). In this system, FLR effects are incorporated through the gyro-averaging of a simplified weak-turbulence model of electrostatic fluctuations. Formally, the GSM is a modified version of the standard map in which the perturbation amplitude, K 0 , becomes K 0 J 0 ($\hat{p}$), where J 0 is the zeroth-order Bessel function and $\hat{p}$ s the Larmor radius. Assuming a Maxwellian probability density function (pdf) for $\hat{p}$ , we compute analytically and numerically the pdf and the cumulative distribution function of the effective drift-wave perturba- tion amplitude K 0 J 0 ($\hat{p}$). Using these results, we compute the probability of loss of confinement (i.e., global chaos), P c provides an upper bound for the escape rate, and that P t rovides a good estimate of the particle trapping rate. Lastly. the analytical results are compared with direct numerical Monte-Carlo simulations of particle transport.

42 ENGINEERING↗

Ab initio no-core solutions for 6 Li

Here, we solve for properties of 6 Li in the ab initio no-core full configuration (NCFC) approach and we separately solve for its ground state and ${J}^{\pi }={2}_{2}^{+}$ resonance with the Gamow shell model (GSM) in the Berggren basis. We employ both the JISP16 and chiral ${\mathrm{NNLO}}_{\mathrm{opt}}$ realistic nucleon–nucleon interactions and investigate the ground state energy, excitation energies, point proton root mean square (rms) radius and a suite of electroweak observables. We also extend and test methods to extrapolate the ground state energy, point proton rms radius, and electric quadrupole moment. We attain improved estimates of these observables in the NCFC approach by using basis spaces up through ${N}_{\max }=18$ that enable more definitive comparisons with experiment. Using the density matrix renormalization group approach with the JISP16 interaction, we find that we can significantly improve the convergence of the GSM treatment of the 6Li ground state and ${J}^{\pi }={2}_{2}^{+}$ resonance by adopting a natural orbital single-particle basis.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Gamow-shell-model description of Li isotopes and their mirror partners

Background: Weakly bound and unbound nuclei close to particle drip lines are laboratories of new nuclear structure physics at the extremes of neutron/proton excess. The comprehensive description of these systems requires an open quantum system framework that is capable of treating resonant and nonresonant many-body states on equal footing. Purpose: In this work, we develop the complex-energy configuration interaction approach to describe binding energies and spectra of selected 5 ≤ $\textit{A}$ ≤ 11 nuclei. Method: We employ the complex-energy Gamow shell model (GSM) assuming a rigid 4 He core. The effective Hamiltonian, consisting of a core-nucleon Woods-Saxon potential and a simplified version of the Furutani-Horiuchi-Tamagaki interaction with the mass-dependent scaling, is optimized in the $\textit{sp}$ space. To diagonalize the Hamiltonian matrix, we employ the Davidson method and the Density Matrix Renormalization Group technique. Results: We report our optimized GSM Hamiltonian offers a good reproduction of binding energies and spectra with the root-mean-square (rms) deviation from experiment of 160 keV. Since the model performs well when used to predict known excitations that have not been included in the fit, it can serve as a reliable tool to describe poorly known states. A case in point is our prediction for the pair of unbound mirror nuclei 10 Li – 10 N in which a huge Thomas-Ehrman shift dramatically alters the pattern of low-energy excitations. Conclusion: The new model will enable comprehensive studies of structure and reactions aspects of light drip-line nuclei.

73 NUCLEAR PHYSICS AND RADIATION PHYSICS↗

Neutron-rich calcium isotopes within realistic Gamow shell model calculations with continuum coupling

Based on the realistic nuclear force of the high-precision CD-Bonn potential, we have performed comprehensive calculations for neutron-rich calcium isotopes using the Gamow shell model (GSM) which includes resonance and continuum. The realistic GSM calculations produce well binding energies, one- and two-neutron separation energies, predicting that 57 Ca is the heaviest bound odd isotope and 70 Ca is the dripline nucleus. Resonant states are predicted, which provides useful information for future experiments on particle emissions in neutron-rich calcium isotopes. Shell evolutions in the calcium chain around neutron numbers $\textit{N}$ = 32, 34, and 40 are understood by calculating effective single-particle energies, the excitation energies of the first 2 + states and two-neutron separation energies. The calculations support shell closures at 52 Ca ($\textit{N}$ = 32) and 54 Ca ($\textit{N}$ = 34) but show a weakening of shell closure at 60 Ca ($\textit{N}$ = 40). Finally, the possible shell closure at 70 Ca ($\textit{N}$ = 50) is predicted.

73 NUCLEAR PHYSICS AND RADIATION PHYSICS↗

New narrow resonances observed in the unbound nucleus F 15

The structure of the unbound 15 F nucleus is investigated using the inverse kinematics resonant scattering of a radioactive 14 O beam impinging on a CH 2 target. The analysis of 1 H( 14 O,p) 14 O and 1 H( 14 O,2p) 13 N reactions allowed the confirmation of the previously observed narrow 1/2 - resonance, near the two-proton decay threshold, and the identification of two new narrow 5/2 - and 3/2 - resonances. The newly observed levels decay by 1p emission to the ground of 14 O, and by sequential 2p emission to the ground state (g.s.) of 13 N via the 1 - resonance of 14 O. Gamow shell model (GSM) analysis of the experimental data suggests that the wave functions of the 5/2 - and 3/2 - resonances may be collectivized by the continuum coupling to nearby 2p- and 1p- decay channels. Finally, the observed excitation function 1 H( 14 O, p) 14 O and resonance spectrum in 15 F are well reproduced in the unified framework of the GSM.

73 NUCLEAR PHYSICS AND RADIATION PHYSICS↗

MOSIQS: Persistent Memory Object Storage With Metadata Indexing and Querying for Scientific Computing

Scientific applications often require high-bandwidth shared storage to perform joint simulations and collaborative data analytics. Shared memory pools provide a chance to satisfy such needs. Recently, a high-speed network such as Gen-Z utilizing persistent memory (PM) offers an opportunity to create a shared memory pool connected to compute nodes. However, there are several challenges to use scientific applications on the shared memory pool directly such as scalability, failure-atomicity, and lack of scientific metadata-based search and query. In this paper, we propose MOSIQS, a persistent memory object storage framework with metadata indexing and querying for scientific computing. We design MOSIQS based on the key idea that memory objects on PM pool can live beyond the application lifetime and can become the sharing currency for applications and scientists. MOSIQS provides an aggregate memory pool atop an array of persistent memory devices to store and access memory objects to accelerate scientific computing. MOSIQS uses a lightweight persistent memory key-value store to manage the metadata of memory objects, which enables memory object sharing. To facilitate metadata search and query over millions of memory objects resident on memory pool, we introduce Group Split and Merge (GSM), a novel persistent index data structure designed primarily for scientific datasets. GSM splits and merges dynamically to minimize the query search space and maintains low query processing time while overcoming the index storage overhead. MOSIQS is implemented on top of PMDK. We evaluate the proposed approach on many-core server with an array of real PM devices. Experimental results show that MOSIQS gains a 100% write performance improvement and executes multi-attribute queries efficiently with 2.7× less index storage overhead offering significant potential to speed up scientific computing applications.

97 MATHEMATICS AND COMPUTING↗

Capturing the response of Clostridium acetobutylicum to chemical stressors using a regulated genome-scale metabolic model

Clostridia are anaerobic Gram-positive Firmicutes containing broad and flexible systems for substrate utilization, which have been used successfully to produce a range of industrial compounds. Clostridium acetobutylicum has been used to produce butanol on an industrial scale through acetone-butanol-ethanol (ABE) fermentation. A genome-scale metabolic (GSM) model is a powerful tool for understanding the metabolic capacities of an organism and developing metabolic engineering strategies for strain development. The integration of stress related specific transcriptomics information with the GSM model provides opportunities for elucidating the focal points of regulation.

59 BASIC BIOLOGICAL SCIENCES↗

Test and Validate Distributed Coaxial Cable Sensors for in situ Condition Monitoring of Coal-Fired Boiler Tubes

This project aims to test, validate, and advance the technology readiness level (from TRL5 to TRL7) of a novel low-cost distributed stainless-steel/ceramic coaxial cable sensing (SSC-CCS) technology for in situ monitoring of the boiler tube temperature in existing coal-fired power plants. The novel SSC-CCS sensing technology and associated condition-based monitoring (CBM) software to be demonstrated in this project will lead to an improved understanding of the boiler tube failure mechanisms and a prognostic system to improve the overall performance, reliability, and flexibility of the nation’s coal-fired power plant fleet. A boiler tube monitoring system with distributed coaxial cable temperature sensors and a sensor acquisition system was constructed. The high-temperature coaxial cable sensor with a length of 1.3m was made by using a quartz tube (1mm inner diameter (ID) and 6mm outer diameter (OD)) to concentrically separate a 304 stainless-steel (SS) rod (1mm OD) and SS tube (7.94mm OD and 6.16mm ID). The sensor acquisition system includes a vector network analyzer (VNA), a radio frequency (RF) power amplifier, multiple switches and a USB hub. The distributed stainless-steel quartz coaxial cable sensor (SSQ-CCS) had a linear response to temperature with a resolution uncertainty of σ = 0.77℃. To withstand the harsh conditions of 3,300 steam pressures and 800℃ high temperatures, the sensor was shielded by a protective tube made of the same material as the boiler tube. The protection tube had an OD of 1.5 inches and a thickness of 0.25 inches. In the laboratory tests, the sensor showed good sensitivity and fast response. The drift was bounded between +0.33% and -0.67% during a test at 600℃ for 350 hours, indicating good stability of the sensor. A field test was conducted where four sensors were welded on four superheat tubes (SH-Ts) at a coal-fired power station over 400 days. Conventional thermocouples were welded to the superheater tubes alongside the coaxial cable sensors for the purpose of comparison. Two sensors were capable of distributed sensing, with three multiplexed sensing sections. The other two sensors were single section. During the 400-day test period, the power plant experienced startups and shutdowns. At the steady state operations, the temperature of the boiler tube is about 600℃ (1112°F). The sensors recorded the entire coal-firing processes (start-up, steady state, and shut-down) and the glitch event. A GSM modem and a Watchdog were added to the system to ensure reliable data recording. The GSM modem sent daily messages to plant managers and Clemson team to inform the status of the sensor system. If the system was not normally working, the Watchdog would reboot the system automatically. The new coaxial cable based distributed sensing technology has been proven to be successful in both laboratory and field tests. A comprehensive four-stage multi-physics computational framework has been developed to assist the design, optimization, installation, and operation of SSQ-CCS. With the consideration of various operation conditions, we predict the distributions of flue gas temperatures within coal-fired boilers, the temperature correlation between the boiler tube and SSQ-CCS, and the safety of SSQ-CCS. A conditional-based monitoring system is implemented as well. The computational framework developed in this work can guide the future operation of coal-fired plants and other power plants for the safety prediction of boiler operations.

01 COAL, LIGNITE, AND PEAT↗

A Genome-Scale Metabolic Model of Anabaena 33047 to Guide Genetic Modifications to Overproduce Nylon Monomers

Nitrogen fixing-cyanobacteria can significantly improve the economic feasibility of cyanobacterial production processes by eliminating the requirement for reduced nitrogen. Anabaena sp. ATCC 33047 is a marine, heterocyst forming, nitrogen fixing cyanobacteria with a very short doubling time of 3.8 h. We developed a comprehensive genome-scale metabolic (GSM) model, iAnC892, for this organism using annotations and content obtained from multiple databases. iAnC892 describes both the vegetative and heterocyst cell types found in the filaments of Anabaena sp. ATCC 33047. iAnC892 includes 953 unique reactions and accounts for the annotation of 892 genes. Comparison of iAnC892 reaction content with the GSM of Anabaena sp. PCC 7120 revealed that there are 109 reactions including uptake hydrogenase, pyruvate decarboxylase, and pyruvate-formate lyase unique to iAnC892. iAnC892 enabled the analysis of energy production pathways in the heterocyst by allowing the cell specific deactivation of light dependent electron transport chain and glucose-6-phosphate metabolizing pathways. The analysis revealed the importance of light dependent electron transport in generating ATP and NADPH at the required ratio for optimal N2 fixation. When used alongside the strain design algorithm, OptForce, iAnC892 recapitulated several of the experimentally successful genetic intervention strategies that over produced valerolactam and caprolactam precursors.

59 BASIC BIOLOGICAL SCIENCES↗

Modification and updating of the Manned Activity Scheduling System (MASS) for shuttle and shuttle payloads analysis. Volume 1: Model specifications

The LRC MASS was modified and updated to include logic for efficient analysis of space shuttle payload operations. All MASS computer models were reviewed for compatibility with, and applicability to, the shuttle sortie mission. The MASS modification efforts were concentrated on two computer programs, the general scheduling model (GSM) and one day model (ODM). A new computer program, the DAYLIB Tape Processor, was developed to update the link between the GSM and ODM. The resulting MASS is an operationally efficient analytical tool that will allow a rapid assessment of shuttle and shuttle payload operations.

Ring, R. C.↗

IMS/Satellite Situation Center report. Predicted orbit plots for Hawkeye 1, 1976

The predicted orbit plots are shown in three projections. The time period covered by each set of projections is 2 days 1 hour, corresponding approximately to the period of Hawkeye 1. The three coordinate systems used are the Geocentric Solar Ecliptic system (GSE), the Geocentric Solar Magnetospheric system (GSM), and the Solar Magnetic system (SM). For each of the three projections, time ticks and codes are given on the satellite trajectories. The codes are interpreted in the table at the base of each plot. Time is given in the table as year/day/decimal hour. The total time covered by each plot is shown at the bottom of each table, and an additional variable is given in the table for each time tick. For the GSM and SM projection this variable is the geocentric distance to the satellite in earth radii, and for the GSE projection the variable is satellite ecliptic latitude in degrees.

Source record↗

IMS/Satellite Situation Center report. Predicted orbit plots for IMP-H-1976

Predicted orbit plots are shown in three projections. The time period covered by each set of projections is 12 days 6 hours, corresponding approximately to the period of IMP-H satellite. The three coordinate systems used are the Geocentric Solar Ecliptic system (GSE), the Geocentric Solar Magnetospheric system (GSM), and the Solar Magnetic system (SM). For each of the three projections, time ticks and codes are given on the satellite trajectories. The codes are interpreted in the table at the base of each plot. Time is given in the table as year/day/decimal hour. The total time covered by each plot is shown at the bottom of each table. An additional variable is given in the table for each time tick. For the GSM and SM projection this variable is the geocentric distance to the satellite in earth radii, and for the GSE projection the variable is satellite ecliptic latitude in degrees.

Source record↗

Twisting of the geomagnetic tail

Theory and models indicate that the IMF causes the magnetotail to produce an observable twist, predicting that the torque should bring the north lobe south of the GSM xy plane on one flank of the magnetotail, and the south lobe north of the plane on the other flank. In this paper, ISEE-3 geotail observations are compared with simultaneously made IMP 8 IMF observations supplemented by inferred IMF B(y) polarities to demonstrate the IMF-induced magnetotail twist. The results indicate that twisting is the single most important factor accounting for observations of the north lobe south of the GSM xy plane and the south lobe north of the plane. The value of the observed magnetotail twist about its aberrated axis is about 18 deg.

Sibeck, D. G.↗

Remote sensing of biomass of salt marsh vegetation in France

Spectral data (gathered using a hand-held radiometer) and harvest data were collected from four salt marsh vegetation types in Brittany, France, to develop equations predicting live aerial biomass from spectral measurements. Remote sensing estimates of biomass of the general salt marsh community (GSM) and of Spartina alterniflora can be obtained throughout the growing season if separate biomass prediction equations are formulated for different species mixtures (for the GSM) and for different canopy types (for S. alterniflora). Results suggest that remote sensing will not be useful for predicting Halimione portulacoides biomass, but can be used to estimate Puccinellia maritima biomass early in the growing season.

Gross, M. F.↗

The effects of dipole tilt on magnetotail structure and dynamics

A three-dimensional time-dependent global magnetohydrodynamic (MHD) model of the interaction between the solar wind and the earth's magnetosphere has been used to study the effects of dipole tilt on the structure and dynamics of the magnetotail. The location of the tail neutral sheet shifts in the north-south direction following changes in the dipole tilt. When the northern edge of the geomagnetic dipole is tilted toward the sun (positive tilt), it is above the geocentric solar magnetosphere (GSM) equator, while for negative tilt, it is below. The neutral sheet forms an arc across the tail in the y-z plane for nonzero tilt. For positive tilt, the neutral sheet rises above the GSM equatorial plane near the noon-midnight meridian and returns to the equator near the magnetopause. The position and shape of the neutral sheet result from the requirement that the earthward magnetic flux equals the tailward flux and can be well explained by a simple analytical model.

Walker, Raymond J.↗

Feasibility of an EHF (40/50 GHz) mobile satellite system using highly inclined orbits

The pan-European L-band terrestrial cellular system (GSM) is expected to provide service to more than 10 million users by the year 2000. Discussed here is the feasibility of a new satellite system at EHF (40/50 GHz) to complement, at the end of the decade, the GSM system or its decendants in order to provide additional services at 64 kbits/s, or so. The main system aspects, channel characteristics, technology issues, and both on-board and earth terminal architectures are highlighted. Based on the performed analyses, a proposal was addressed to the Italian Space Agency (ASI), aimed at the implementation of a national plan.

Falciasecca, G.↗