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At least 55 records · Page 3

A Novel Telometric Metric for In-Situ Measurement of Intrauterine Pressure (IUP) in Pregnant and Parturient Rats

During labor and birth, considerable forces exerted on fetuses help instigate certain adaptive postpartum responses (viz., breathing and suckling). To make precise, reliable measures of the forces experienced by rat fetuses during parturition, we developed a novel method for measuring intrauterine pressure (IUP) in late pregnant rats. A small (1.25 x 4cm) telemetric blood pressure sensor is fitted within a fluid-filled balloon, similar in size to a full term rat fetus. The balloon is surgically implanted in the uterus on Gestational Day 19 of the rats' 22-day pregnancy. During birth, dams are able to deliver their pups and the balloon. IUP arsenals are recorded during labor (G22 or 23) and birth. Data derived from a group of implanted rats indicated that pressures on the balloon increased across the period of birth, reaching 18 mmHg during labor, 25 mmHg during pup births and 39 mmHg just prior to delivery of the balloon. These data are within the range reported for conventional IUP measurement techniques. Dams are simultaneously videotaped, enabling us to analyze behavioral expressions of labor contractions and to integrate in-situ and behavioral findings.

Baer, Lisa A.↗

Correlative Analysis of Behavioral and Physiological Concomitants of Labor in Pregnant Rats

During parturition, rats exhibit characteristic behavioral expressions of labor. Lordosis contractions, consisting of an elongation of the dams body, are observed beginning several hours prior to neonate births, whereas vertical contractions, repeated rapid lifts of the abdomen, occur immediately preceding the birth of each neonate. We analyzed underlying changes in intrauterine pressure (IUP) using a telemetric sensor that we modified for use in freely-moving rats. This technique enabled us to correlate behavioral expressions of labor contractions with IUP. A small telemetric blood pressure sensor was fitted within a fluid-filled balloon, similar in size to a full term rat fetus. On Gestational day 19 of the rats' 22-day pregnancy, a unit was surgically implanted within the uterus. The dams were simultaneously videotaped, enabling us to directly correlate IUP signals with behavioral expressions of labor contractions. Earlier phases of labor, consisting predominantly of lordosis contractions were characterized by lower pressures relative to later phases during which higher pressures and vertical contractions were frequently observed.

Baer, L. A.↗

Behavioral and Physiological Analyses of Parturition In Pregnant Rats: Insights Derived from Intrauterine Telemetry

During labor and birth, fetuses are exposed to considerable physical stimulation associated with labor contractions and expulsion from the womb These forces are important for the neonates' adaptation to tile extrauterine environment. To further our understanding of the relationship between labor and postpartum outcome, we developed a novel method for measuring intrauterine pressure (IUP) in freely-moving, late pregnant and parturient rats that enables us to make precise, reliable measures of the forces experienced by rat fetuses during parturition. A small (1.25 x 4 cm) telemetric blood pressure sensor was fitted within a fluid-filled balloon, similar in size to a full term rat fetus. On Gestational day (G) 19 of the rats' 22/23 day pregnancy, each dam was anesthetized and a balloon/sensor unit surgically implanted within the uterus following removal of two fetuses. Comparisons were made between sensor-implanted dams (IMPL) and a control conditions: 1) LAP-R, laparotomy with two fetuses removed or 2) LAP-NR, laparotomy with no fetuses removed. IUP signals were sampled at 10s intervals from the IMPL dams during labor and birth. Dams in all three conditions were videorecorded enabling us to analyze the effect of the implant on behavioral expressions of parturition. Contraction frequency, duration, pup-to-pup birth intervals and pup-oriented activities of the dams measured from one hour prior to the first pup birth until the birth of the third pup were unaffected by the sensor implant. Intrauterine telemetry of freely-moving dams offers significant advantages over conventional hardwired IUP measurement techniques. These findings establish and validate intrauterine telemetry as a reliable, non-invasive technique for quantifying pressures associated with parturition.

Villareal, J.↗

Revised and extended benchmark results for Rayleigh scattering of sunlight in spherical atmospheres

While most of traditional Earth-atmosphere satellite remote sensing relies on radiative transfer in the plane parallel geometry, effects of sphericity are important at high sun and view zenith angles. Broad understanding of these effects is limited and, contrary to the plane-parallel case, finding accurate numerical results to test spherical RT codes is not easy. This paper aims to partially fill in this gap. Using the full-spherical RT code MYSTIC (Monte Carlo), and the plane-parallel RT code VLIDORT (discrete ordinates) corrected for atmospheric sphericity in the single and multiple scattering, we reproduced with better accuracy and extended the benchmark results by Adams & Kattawar [1978].

spherical atmospheres↗

Asbestos Free Insulation Development for the Space Shuttle Solid Propellant Rocket Motor (RSRM)

Asbestos has been used for many years as an ablation inhibitor in insulating materials. It has been a constituent of the AS/NBR insulation used to protect the steel case of the RSRM (Reusable Solid Rocket Motor) since its inception. This paper discusses the development of a potential replacement RSRM insulation design, several of the numerous design issues that were worked and processing problems that were resolved. The earlier design demonstration on FSM-5 (Flight Support Motor) of the selected 7% and 11% Kevlar(registered) filled EPDM (KF/EPDM) candidate materials was expanded. Full-scale process simulation articles were built and FSM-8 was manufactured using multiple Asbestos Free (AF) components and materials. Two major problems had to be overcome in developing the AF design. First, bondline corrosion, which occurred in the double-cured region of the aft dome, had to be eliminated. Second, KF/EPDM creates high levels of electrostatic energy (ESE), which does not readily dissipate from the insulation surface. An uncontrolled electrostatic discharge (ESD) of this surface energy during many phases of production could create serious safety hazards. Numerous processing changes were implemented and a conductive paint was developed to prevent exposed external insulation surfaces from generating ESE/ESD. Additionally, special internal instrumentation was incorporated into FSM-8 to record real-time internal motor environment data. These data included inhibitor insulation erosion rates and internal thermal environments. The FSM-8 static test was successfully conducted in February 2000 and much valuable data were obtained to characterize the AF insulation design.

Allred, Larry D.↗

The 12x32 Pop-Up Bolometer Array for the SHARC II Camera

SHARC II is a 350 micron facility camera for the Caltech Submillimeter Observatory (CSO) expected to come on-line in 2002. The key component of SHARC II is a 12x32 array of doped silicon 'pop-up' bolometers developed at NASA/Goddard and delivered to Caltech in March 2002. Each pixel is 1 mm x 1 mm, coated with a 400 Omega/square bismuth film, and located lambda/4 above a reflective backshort to maximize radiation absorption. The pixels cover the focal plane with greater than 95% filling factor. Each doped thermistor occupies nearly the full area of the pixel to minimize 1/f noise. We report some results from the first cold measurements of this array. The bolometers were located inside a dark cover, and 4x32 pixels were read simultaneously. In the best 25% of winter nights on Mauna Kea, SHARC II is expected to have an NEFD at 350 microns of 1 Jy s(sup 1/2) or better.

Dowell, C. Darren↗

Radio Frequency Mass Gauging of Propellants

A combined experimental and computer simulation effort was conducted to measure radio frequency (RF) tank resonance modes in a dewar partially filled with liquid oxygen, and compare the measurements with numerical simulations. The goal of the effort was to demonstrate that computer simulations of a tank's electromagnetic eigenmodes can be used to accurately predict ground-based measurements, thereby providing a computational tool for predicting tank modes in a low-gravity environment. Matching the measured resonant frequencies of several tank modes with computer simulations can be used to gauge the amount of liquid in a tank, thus providing a possible method to gauge cryogenic propellant tanks in low-gravity. Using a handheld RF spectrum analyzer and a small antenna in a 46 liter capacity dewar for experimental measurements, we have verified that the four lowest transverse magnetic eigenmodes can be accurately predicted as a function of liquid oxygen fill level using computer simulations. The input to the computer simulations consisted of tank dimensions, and the dielectric constant of the fluid. Without using any adjustable parameters, the calculated and measured frequencies agree such that the liquid oxygen fill level was gauged to within 2 percent full scale uncertainty. These results demonstrate the utility of using electromagnetic simulations to form the basis of an RF mass gauging technology with the power to simulate tank resonance frequencies from arbitrary fluid configurations.

Zimmerli, Gregory A.↗

Vehicle Sketch Pad: a Parametric Geometry Modeler for Conceptual Aircraft Design

The conceptual aircraft designer is faced with a dilemma, how to strike the best balance between productivity and fidelity? Historically, handbook methods have required only the coarsest of geometric parameterizations in order to perform analysis. Increasingly, there has been a drive to upgrade analysis methods, but these require considerably more precise and detailed geometry. Attempts have been made to use computer-aided design packages to fill this void, but their cost and steep learning curve have made them unwieldy at best. Vehicle Sketch Pad (VSP) has been developed over several years to better fill this void. While no substitute for the full feature set of computer-aided design packages, VSP allows even novices to quickly become proficient in defining three-dimensional, watertight aircraft geometries that are adequate for producing multi-disciplinary meta-models for higher order analysis methods, wind tunnel and display models, as well as a starting point for animation models. This paper will give an overview of the development and future course of VSP.

Hahn, Andrew S.↗

Providing Housing, Food and Medical Support for 25,000 Katrina Evacuees with 12 Hours Notice: The Harris County Medical Support of the Superdome Evacuees

Hurricane Katrina was responsible for trapping 25,000 people in the New Orleans Superdome and isolating many others throughout Louisiana and Mississippi. The transport of these evacuees to the Reliant Park (Houston, Texas) used 500 buses each containing about 55 people. Processing the arriving evacuees included addressing their health status and medical needs as follows: an initial triage at disembarkation, a secondary triage in the Reliant Astrodome and Center, and definitive clinical care in the Reliant Arena "Katrina" Clinic. Baylor College of Medicine (BCM) physicians boarded buses and identified the sickest for emergency transport to Harris County Hospital District (HCHD) hospitals. BCM departments represented included pediatrics, family and community medicine, internal medicine, radiology, obstetrics and gynecology, orthopedics, surgery, and psychiatry. Astrodome and Center triage was managed by BCM physicians and staffed by HCHD Nurses and volunteers from Texas and beyond. The Reliant Astrodome, Center and Arena reached peak headcounts of 15,000,4500, and 2500, respectively Most evacuees visiting the triage sites in the Astrodome and Center were treated using "over-the-counter" medications with the remaining being transported to the "Katrina" clinic. The clinic was equipped with a lab, pharmacy, digital X-ray, and ultrasound machines in addition to electronic patient records created using 80 computer terminals. The Katrina clinic saw more than 15,000 patients during 15 days of operations (2,000 on the first full day), administered 10,000 tetanus shots, and filled thousands of prescriptions. At the peak of operations, the clinic saw 150 patients/hour with 25 physicians scheduled for each 12-hour shift. Approximately 900 people were transported to hospital emergency rooms. Within 3 weeks of arriving at the Reliant Park facilities, more than 90% of the families found permanent housing, enrolled children in schools, and found work. Using data obtained from manual and electronic medical records, this presentation will document the major milestones and lessons learned from this extraordinary project to help the Katrina evacuees.

Hamilton, Douglas↗

Historic Emissions from Deforestation and Forest Degradation in Mato Grosso, Brazil: 1. Source Data Uncertainties

Historic carbon emissions are an important foundation for proposed efforts to Reduce Emissions from Deforestation and forest Degradation and enhance forest carbon stocks through conservation and sustainable forest management (REDD+). The level of uncertainty in historic carbon emissions estimates is also critical for REDD+, since high uncertainties could limit climate benefits from mitigation actions. Here, we analyzed source data uncertainties based on the range of available deforestation, forest degradation, and forest carbon stock estimates for the Brazilian state of Mato Grosso during 1990-2008. Results: Deforestation estimates showed good agreement for multi-year trends of increasing and decreasing deforestation during the study period. However, annual deforestation rates differed by >20% in more than half of the years between 1997-2008, even for products based on similar input data. Tier 2 estimates of average forest carbon stocks varied between 99-192 Mg C/ha, with greatest differences in northwest Mato Grosso. Carbon stocks in deforested areas increased over the study period, yet this increasing trend in deforested biomass was smaller than the difference among carbon stock datasets for these areas. Conclusions: Patterns of spatial and temporal disagreement among available data products provide a roadmap for future efforts to reduce source data uncertainties for estimates of historic forest carbon emissions. Specifically, regions with large discrepancies in available estimates of both deforestation and forest carbon stocks are priority areas for evaluating and improving existing estimates. Full carbon accounting for REDD+ will also require filling data gaps, including forest degradation and secondary forest, with annual data on all forest transitions.

Morton, Douglas C.↗

ODC-Free Solvent Implementation Issues for Vulcanized Rubber and Bond Systems

Thiokol Propulsion has worked extensively to replace 1,1,1-trichloroethane (TCA) with ozone depleting chemicals (ODC)-free solvents for use in the manufacture of the Reusable Solid Rocket Motor (RSRM) for the Space Shuttle Program. As Thiokol has transitioned from sub-scale to full-scale testing and implementation of these new solvents, issues have been discovered which have required special attention. The original intent of Thiokol's solvent replacement strategy was to replace TCA with a single drop-in solvent for all equivalent applications. We have learned that a single candidate does not exist for replacing TCA. Solvent incompatibility with process materials has caused us to seek for niche solvents and/or processing changes that provide an ODC-free solution for special applications. This paper addresses some of the solvent incompatibilities, which have lead to processes changes and possible niche solvent usage. These incompatibilities were discovered during full-scale testing of ODC-free solvents and relate to vulcanized rubber and bond systems in the RSRM. Specifically, the following items are presented: (1) Cure effects of d-limonene based solvents on Silica Filled Ethylene Propylene Diene Monomer (SF-EPDM) rubber. During full-scale test operations, Thiokol discovered that d-limonene (terpene) based solvents inhibit the cure of EPDM rubber. Subsequent testing showed the same issue with Nitrile Butadiene Rubber (NBR). Also discussed are efforts to minimize uncured rubber exposure to solvents; and (2) Cured bond system sensitivity to ODC-free solvents. During full scale testing it was discovered that a natural rubber to steel vulcanized bond could degrade after prolonged exposure to ODC-free solvents. Follow on testing showed that low vapor pressure and residence time seemed to be most likely cause for failure.

Hodgson, James R.↗

Optical Observations of GEO Debris with Two Telescopes

For several years, the Michigan Orbital DEbris Survey Telescope (MODEST), the University of Michigan s 0.6/0.9-m Schmidt telescope on Cerro Tololo Inter-American Observatory in Chile has been used to survey the debris population at GEO in the visible regime. Magnitudes, positions, and angular rates are determined for GEO objects as they move across the telescope s field-of-view (FOV) during a 5-minute window. This short window of time is not long enough to determine a full six parameter orbit so usually a circular orbit is assumed. A longer arc of time is necessary to determine eccentricity and to look for changes in the orbit with time. MODEST can follow objects in real-time, but only at the price of stopping survey operations. A second telescope would allow for longer arcs of orbit to obtain the full six orbital parameters, as well as assess the changes over time. An additional benefit of having a second telescope is the capability of obtaining BVRI colors of the faint targets, aiding efforts to determine the material type of faint debris. For 14 nights in March 2007, two telescopes were used simultaneously to observe the GEO debris field. MODEST was used exclusively in survey mode. As objects were detected, they were handed off in near real-time to the Cerro Tololo 0.9-m telescope for follow-up observations. The goal was to determine orbits and colors for all objects fainter than R = 15th magnitude (corresponds to 1 meter in size assuming a 0.2 albedo) detected by MODEST. The hand-off process was completely functional during the final eight nights and follow-ups for objects from night-to-night were possible. The cutoff magnitude level of 15th was selected on the basis of an abrupt change in the observed angular rate distribution in the MODEST surveys. Objects brighter than 15th magnitude tend to lie on a well defined locus in the angular rate plane (and have orbits in the catalog), while fainter objects fill the plane almost uniformly. We need to determine full six-parameter orbits to investigate what causes this change in observed angular rates. Are these faint objects either the same population of high area-to-mass (A/M) objects on eccentric orbits as discovered by the ESA Space Debris Telescope (Schildknecht, et al. 2004), or are they just normal debris from breakups in GEO?

Seitzer, P.↗

In Situ Alloying Enabled by Active Liquid Metal Filler for Self‐Healing Composite Polymer Electrolytes

Abstract Solid inorganics, known for kinetically inhibiting polymer crystallization and enhancing ionic conductivity, have attracted significant attention in solid polymer electrolytes. However, current composite polymer electrolytes (CPEs) are still facing challenges in Li metal batteries, falling short of inhibiting severe dendritic growth and resulting in very limited cycling life. This study introduces Ga 62.5 In 21.5 Sn 16 (Galinstan) liquid metal (LM) as an active liquid alternative to conventional passive solid fillers, aiming at realizing self‐healing protection against dendrite problems. Compared to solid inorganics, for example silica, LM droplets could more significantly reduce polymer crystallinity and enhance Li‐ion conductivity due to their liquid nature, especially at temperatures below the polymer melting point. More importantly, LMs are unraveled as dynamic chemical traps, which are capable of blocking and consuming lithium dendrites upon contact via in situ alloying during battery operation and further inhibiting dendritic growth due to the lower deposition energy barrier of the formed Li‐LM alloy. As a proof of concept, by strategically designing an asymmetric CPE with the active LM filling, a solid‐state Li/LiFePO 4 battery achieves promising full‐cell functionality with notable rate performance and stable cycle life. This active filler‐mediated self‐healing approach could bring new insights into the battery design in versatile solid‐state systems.

Wu, Kai↗

Hypervelocity Impact Testing of Nickel Hydrogen Battery Cells

Nickel-Hydrogen (Ni/H2) battery cells have been used on several satellites and are planned for use on the International Space Station. In January 1992, the NASA Lewis Research Center (LeRC) conducted hypervelocity impact testing on Ni/H2 cells to characterize their failure modes. The cell's outer construction was a 24 mil-thick Inconel 718 pressure vessel. A sheet of 1.27 cm thick honeycomb was placed in front of the battery cells during testing to simulate the on-orbit box enclosure. Testing was conducted at the NASA White Sands Test Facility (WSTF). The hypervelocity gun used was a 7.6 mm (0.30 caliber) two-stage light gas gun. Test were performed at speeds of 3, 6, and 7 km/sec using aluminum 2017 spherical particles of either 4.8 or 6.4 mm diameter as the projectile. The battery cells were electrically charged to about 75 percent of capacity, then back-filled with hydrogen gas to 900 psi simulating the full charge condition. High speed film at 10,000 frames/sec was taken of the impacts. Impacts in the dome area (top) and the electrode area (middle) of the battery cells were investigated. Five tests on battery cells were performed. The results revealed that in all of the test conditions investigated, the battery cells simply vented their hydrogen gas and some electrolyte, but did not burst or generate any large debris fragments.

Frate, David T.↗

Prediction of Emission from Wire Polarizing Grids

A simple inhomogeneous circuit model for a grid comprised of wires with circular cross section is derived and compared to measured observations. The proposed approximations are valid in the limit the geometric parameters for the grid are small compared to the wavelength of the incident radiation. Expressions for the emission, reflection, and transmission are provided. The accuracy of this circuit model is compared against full wave numerical simulations as a function of grid filling fraction. For perpendicular illumination of the grid the expressions used in the literature for zero thickness polarizers are recovered. For parallel illumination the influence of the finite wire thickness has a non-negectable influence on the emission properties of a wire grid polarizer is found.

Wollack, Edward↗

Pratt and Whitney cryogenic turbopump bearing experience

Successful, reusable bearings require lubrication, traditionally, a transfer film from sacrificial cage wear. Early testing included materials screening programs to identify suitable cryogenic cage materials. A specially developed element tester that simulated the function of a ball bearing cage was used. Suitable materials must provide lubrication with an acceptably low wear rate, without abrading contacting surfaces. The most promising materials were tested in full scale bearings at speeds up to 4 MDN. Teflon, filled with 40 percent bronze powder, was the best performing material. A variety of bearings were designed and successfully tested in LH2 and LOX. Bearings with bronze filled Teflon cages were successfully tested for 150 hrs. In overload tests, the same design was tested for 5 hrs at maximum Hertz stresses above 450 ksi and an additional 5 hrs with a maximum Hertz stress exceeding 500 ksi. Four bearings were tested in LOX for 25 hrs, with a maximum time per bearing of 10 hrs.

Poole, W. E.↗

Fluid System Angular Momentum and Moment Fluctuations Driven by Gravity Gradient or Gravity Jitter in Microgravity

The dynamical behaviour of fluids affected by the asymmetric gravity gradient acceleration and gravity jitter acceleration, in particular the effect of surface tension on partially-filled rotating fluids with special example applicable to a full-scale Gravity Probe-B Spacecraft dewar tank have been investigated. Results of slosh wave excitation along liquid-vapor interface induced by gravity gradient acceleration indicated that one-up one-down and one-down one-up oscillations of two bubbles in the cross-section of doughnut profiles in the vertical r-z plane of rotating dewar, and an eccentric contour of bubble rotating around the axis of dewar in horizontal r-Theta plane. Results of slosh wave excitation along liquid-vapor interface induced by gravity jitter acceleration indicated equivalent to time-dependent oscillatory forces which push bubble in the combined bubble motion of down-and-up and leftward-and-rightward as the bubble is rotating with respect to rotating dewar axis. Fluctuations of angular momentum, fluid moment and bubble mass center caused by slosh wave excitations driven by gravity gradient acceleration or gravity jitter acceleration are also investigated.

Hung, R. J.↗

Defective secretion of mucilage is the cellular basis for agravitropism in primary roots of Zea mays cv. Ageotropic

Root caps of primary, secondary, and seminal roots of Z. mays cv. Kys secrete large amounts of mucilage and are in close contact with the root all along the root apex. These roots are strongly graviresponsive. Secondary and seminal roots of Z. mays cv. Ageotropic are also strongly graviresponsive. Similarly, their caps secrete mucilage and closely appress the root all along the root apex. However, primary roots of Z. mays cv. Ageotropic are non-responsive to gravity. Their caps secrete negligible amounts of mucilage and contact the root only at the extreme apex of the root along the calyptrogen. These roots become graviresponsive when their tips are coated with mucilage or mucilage-like materials. Peripheral cells of root caps of roots of Z. mays cv. Kys contain many dictyosomes associated with vesicles that migrate to and fuse with the plasmalemma. Root-cap cells of secondary and seminal (i.e. graviresponsive) roots of Z. mays cv. Ageotropic are similar to those of primary roots of Z. mays cv. Kys. However, root-cap cells of primary (i.e. non-graviresponsive) roots of Z. mays cv. Ageotropic have distended dictyosomal cisternae filled with an electron-dense, granular material. Large vesicles full of this material populate the cells and apparently do not fuse with the plasmalemma. Taken together, these results suggest that non-graviresponsiveness of primary roots of Z. mays cv. Ageotropic results from the lack of apoplastic continuity between the root and the periphery of the root cap. This is a result of negligible secretion of mucilage by cells along the edge of the root cap which, in turn, appears to be due to the malfunctioning of dictyosomes in these cells.

NASA Discipline Number 29-20↗