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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 55 records · Page 3

Transferrin receptor targeting by de novo sheet extension

The de novo design of polar protein–protein interactions is challenging because of the thermodynamic cost of stripping water away from the polar groups. Here, we describe a general approach for designing proteins which complement exposed polar backbone groups at the edge of beta sheets with geometrically matched beta strands. We used this approach to computationally design small proteins that bind to an exposed beta sheet on the human transferrin receptor (hTfR), which shuttles interacting proteins across the blood–brain barrier (BBB), opening up avenues for drug delivery into the brain. We describe a design which binds hTfR with a 20 nM K d , is hyperstable, and crosses an in vitro microfluidic organ-on-a-chip model of the human BBB. Our design approach provides a general strategy for creating binders to protein targets with exposed surface beta edge strands.

59 BASIC BIOLOGICAL SCIENCES↗

De novo design of transmembrane β barrels

Transmembrane β-barrel proteins (TMBs) are of great interest for single-molecule analytical technologies because they can spontaneously fold and insert into membranes and form stable pores, but the range of pore properties that can be achieved by repurposing natural TMBs is limited. We leverage the power of de novo computational design coupled with a “hypothesis, design, and test” approach to determine TMB design principles, notably, the importance of negative design to slow β-sheet assembly. We design new eight-stranded TMBs, with no homology to known TMBs, that insert and fold reversibly into synthetic lipid membranes and have nuclear magnetic resonance and x-ray crystal structures very similar to the computational models. These advances should enable the custom design of pores for a wide range of applications.

Vorobieva, Anastassia A.↗

Near-conjugate observations of inverted-V electron precipitation using DE 1 and DE 2

A major focus of auroral research has been related to the inverted-V electron precipitation event, distinguished by the 'inverted-V' variation of peak energy flux in an energy-time spectrogram. Thieman and Hoffman (1984), in an examination of plasma data from near-conjugate DE 1/2 passes in the southern hemisphere, have found that some inverted-V events remain reasonably stable over a time span of up to 18 min, while other events change over shorter time periods. The present investigation has the objective to study quantitatively the energization of inverted-V electron fluxes and to compare the results with predictions from adiabatic acceleration by an electrostatic field. The obtained results suggest that the turbulent processes might contirbute minimally to the energy flux of secondary electrons for some events, but significantly for others.

Lin, C. S.↗

Programa de Diseno, Fabricacion y Pruebas del Sistema de Desalinizacion por Olas del NREL: Preprint (Spanish Translation)

To de-risk the U.S. Department of Energy's Waves to Water Prize, the National Renewable Energy Laboratory (NREL) developed a modular, wave powered desalination system. The prize was open to wave energy converter (WEC) designs that generate electricity or WECs that desalinate water mechanically. This added installation risks due to the variance in competitor devices, and the aggressive installation timeline. To reduce these risks NREL developed a wave energy converter (WEC) that the installation team could use to practice installation techniques prior to the competitors arriving to ensure all steps had been considered prior to the event. This was achieved by developing a WEC with a modular power-take-off (PTO). The modular PTO can be configured in one configuration to drive an electric generator that sends electricity to a pier. The electricity that is generated is converted, and stored, so that it can be used to power an electric pump that feeds water to a Reverse Osmosis (RO) desalination unit. In the other configuration the generator is replaced with a pump and seawater is pumped to the RO system on the pier without any electrons being generated. This WEC is formally known as the Hydraulic and Electric Reverse Osmosis (HERO) WEC. For the English version of this report, see NREL/CP-5700-86623 (https://www.nrel.gov/docs/fy24osti/86623.pdf).

laboratory testing↗

Recommendations for Establishing Local Rural Electrification Programs Using Photovoltaic Systems [Recomendaciones Para la Implantacidn de Programas Locales de Electrificacidn Rural con Sistemas Fotovoltaicos]

Photovoltaic (PV) technology is becoming one the best options for supplying electricity to rural communities far from electrical networks and which have a small and disperse demand for electricity. As the cost of the technology goes down and its development advances, opportunities for applying it continue to grow. As a result, in the near future we will probably see an increase in massive application programs of this technology in rural Mexico. This document presents some of the most relevant problems needing immediate solution to increase the possibility of success in establishing photovoltaic programs for rural electrification in Mexico. These problems are influenced by economic, technological, engineering, infrastructural, social and political issues. The paper presents the requirements for an industrial center based on PV technology, the accessibility of replacement parts and maintenance service, development of financial solutions, training of the users and introducing norms and technical regulations. The document summarizes the issue of rural electrification in Mexico, emphasizing the low population density in these areas. A brief description is given of photovoltaics showing different configurations that can be utilized for supplying electricity to the rural areas. The issues involved and recommendations for introducing PV systems to the rural area are described.

14 SOLAR ENERGY↗

Techno-economic analysis of biomass value-added processing informed by pilot scale de-ashing of paper sludge feedstock

Paper sludge biomass represents an underutilized feedstock rich in pulped and processed cellulose which is currently a waste stream with significant disposal cost to industry for landfilling services. Effective fractionation of the cellulose from paper sludge presents an opportunity to yield cellulose as feedstock for value-added processes. A novel approach to cellulose fractionation is the sidehill screening system, herein studied at the pilot-plant scale. Composition analysis determined ash removal and carbohydrate retention of both sidehill and high-performance benchtop screening systems. Sidehill screening resulted in greater carbohydrates retention relative to benchtop screening (90% vs 66%) and similar ash removal (95% vs 98%). Techno-economic analysis for production of sugar syrup yielded a minimum selling price of $331/metric ton of sugar syrup including disposal savings, significantly less than a commercial sugar syrup without fractionation. Furthermore, sensitivity analysis showed that screening conditions played a significant role in economic feasibility for cellulosic yield and downstream processes.

09 BIOMASS FUELS↗

Session de formation de l'USAID en Haiti n2: Introduction a l'outil Engage [Slides]

Welcome to Engage! Engage is a capacity expansion modeling tool supported by the National Renewable Energy Laboratory and based on the Calliope open-source capacity expansion model developed by the ETH Zurich University, maintained at the TU Delft University. Engage is an accessible (free, open-access, web-hosted) and flexible web-based energy system planning application for rapid multiple-energy-form energy system scenario exploration. Its cloud-based, collaborator-sharable data model, intuitive interface and visualization capabilities facilitate collaboration and communication among teams, with experts, and among diverse stakeholder groups exploring energy system implications from district to national-scale models. This training series was developed under USAID to empower Haitian stakeholders to explore modeling scenarios in Engage to develop a Haiti Energy Master Plan. This training series includes a general overview of how Engage works along with tailored exercises that target Haiti's specific energy needs, such as modeling the capacity expansion of the bulk power system, fuel scarcity challenges, the development of microgrids, and the economic viability of transmission strategies. See NREL/PR-7A40-88836 for the English translation of this document.

24 POWER TRANSMISSION AND DISTRIBUTION↗

Seance de formation de l'USAID en Haiti n3: Expansion des capacites [Slides]

Welcome to Engage! Engage is a capacity expansion modeling tool supported by the National Renewable Energy Laboratory and based on the Calliope open-source capacity expansion model developed by the ETH Zurich University, maintained at the TU Delft University. Engage is an accessible (free, open-access, web-hosted) and flexible web-based energy system planning application for rapid multiple-energy-form energy system scenario exploration. Its cloud-based, collaborator-sharable data model, intuitive interface and visualization capabilities facilitate collaboration and communication among teams, with experts, and among diverse stakeholder groups exploring energy system implications from district to national-scale models. This training series was developed under USAID to empower Haitian stakeholders to explore modeling scenarios in Engage to develop a Haiti Energy Master Plan. This training series includes a general overview of how Engage works along with tailored exercises that target Haiti's specific energy needs, such as modeling the capacity expansion of the bulk power system, fuel scarcity challenges, the development of microgrids, and the economic viability of transmission strategies. See NREL/PR-7A40-88837 for the English translation of this document.

24 POWER TRANSMISSION AND DISTRIBUTION↗

Implementación acelerada del almacenamiento de energía en los países de RELAC [Accelerated Energy Storage Deployment in RELAC Countries]

"Renewables in Latin America and the Caribbean" or RELAC is a regional initiative across Latin America and the Caribbean (LAC) that was created at the end of 2019, within the framework of the United Nations Climate Action Summit, with the objective of reaching at least 70% of renewable energy installed capacity, and 80% of the region's total electricity generation from renewables by 2030. 16 countries are members (Barbados, Bolivia, Chile, Colombia, Costa Rica, Dominican Republic, Ecuador, El Salvador, Guatemala, Haiti, Honduras, Nicaragua, Panama, Paraguay, Peru, and Uruguay), and others are in discussions to join. RELAC provides these countries with support in addressing technical and financial needs to increase renewable energy penetration, matchmaking with financial resources to support capacity building needs and implementation of RE expansion plans, and knowledge exchange via peer-learning, and best practices in renewable energy integration to the electrical grid. This is the Spanish translation of NREL/TP-7A40-89643.

29 ENERGY PLANNING, POLICY, AND ECONOMY↗

De novo Materials Design of Catalytic Surface Motifs for Water-Gas-Shift (Final Progress Report DOE Grant DE-SC0019281)

This project was aimed at developing innovative theoretical methods and models to understand essential catalysis-relevant issues such as CO 2 conversion, fuel cells, and lithium batteries. Through collaborations with experimentalists, we strive to develop new quantum and machine learning methods for the understanding of surface and interfacial chemistry that can empower the design of energy and sustainability systems. Overall, our work under this grant brings cross-disciplinary insights into catalytic materials, microenvironments, and other conditions, which can serve to provide design rules for the next generation of catalysts.

25 ENERGY STORAGE↗