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At least 55 records · Page 3

Reanalysis of Rodent Data from Spacelab Life Sciences-1

The space bioscience field has long been plagued by the challenge of spaceflight with effects of radiation and microgravity. Having multiple and repeated spaceflight experiments for model organisms to solve these space stressors is costly and time consuming. Therefore, reusing and reanalyzing legacy experiments is one way that scientists can draw new conclusions in a timely manner and without using too many resources. Moreover, advances in general biological knowledge allows legacy experiments to be placed into more complete context.Here we aim to analyze all data and metadata taken from rats flown on the SLS-1 mission to create a comprehensive biological model that can be supplemented with current data to allow new discoveries in how space flown organisms adapt to the space environment. Our approach begins with the identification of all the data and metadata, including graphs and tables, for SLS-1 in NASA archives and other sources. Then, each piece of data and metadata will be digitized, reformatted and analyzed. Lastly, a previously developed astronaut model will be used to create the data framework and a comprehensive biological rodent model. The datasets we are using is from the 1991 SpaceLab Life Science 1 (SLS-1) NASA Mission. This was the first designated spacelab mission flown. All 29 rodents were tested for nine days in two different habitats: Research Animal Holding Facility (RAHF) and Animal Enclosure Module (AEM). The rodents were prepared for a live return and compared to a ground control. A total of 30 rodent experiments were accepted as flight studies on the mission. By digitization and reorganizing SLS-1 rat data we will both directly generate new insights and indirectly enable other scientists to by providing the data and metadata in a digitized form.

Space Biology↗

Reanalysis of Rodent Data from Spacelab Life Science-1

The space bioscience field has long been plagued by the challenge of spaceflight with effects of radiation and microgravity. Having multiple and repeated spaceflight experiments for model organisms to solve these space stressors is costly and time consuming. Therefore, reusing and reanalyzing legacy experiments is one way that scientists can draw new conclusions in a timely manner and without using too many resources. Moreover, advances in general biological knowledge allows legacy experiments to be placed into more complete context.Here we aim to analyze all data and metadata taken from rats flown on the SLS-1 mission to create a comprehensive biological model that can be supplemented with current data to allow new discoveries in how space flown organisms adapt to the space environment. Our approach begins with the identification of all the data and metadata, including graphs and tables, for SLS-1 in NASA archives and other sources. Then, each piece of data and metadata will be digitized, reformatted and analyzed. Lastly, a previously developed astronaut model will be used to create the data framework and a comprehensive biological rodent model. The datasets we are using is from the 1991 SpaceLab Life Science 1 (SLS-1) NASA Mission. This was the first designated spacelab mission flown. All 29 rodents were tested for nine days in two different habitats: Research Animal Holding Facility (RAHF) and Animal Enclosure Module (AEM). The rodents were prepared for a live return and compared to a ground control. A total of 30 rodent experiments were accepted as flight studies on the mission. By digitization and reorganizing SLS-1 rat data we will both directly generate new insights and indirectly enable other scientists to by providing the data and metadata in a digitized form.

Space Biology↗

The use of mineral crystals as bio-markers in the search for life on Mars

It is proposed that minerals resulting from biologically controlled mineralization processes be utilized as biomarkers because of their favorable qualities. Universal signatures of life (biomarkers) are discussed in terms of their terrestrial forms and hypothetical Martian counterparts including organics, suites of specific inorganic and organic compounds, and isotopic ratios. It is emphasized that minerals produced under biologic control have morphological and isotopic compositions that are not found in their abiotic counterparts. Other biomarkers are not necessarily indicative of biological origin and are therefore unreliable resources for scientific study. Mineral crystals are also stable over long geological periods, and the minerals from Martian fluvial features can therefore be employed to search for fossils and biomarkers of early biological activity.

Schwartz, D. E.↗

Use of Drying Technologies for Resource Recovery from Solid Wastes and Brines

Long term storage of unprocessed biological wastes and human wastes can present major health issues and a loss of potential resources. Space vehicles and planetary habitats are typically resource-scarce or resource-limited environments for long-term human habitation. To-date, most of the resources will need to be supplied from Earth, but this may not be possible for long duration human exploration. Based on present knowledge, there is only very limited in-situ resources on planetary habitats. Hence, the opportunity to "live off the land" in a planetary habitat is limited. However, if we assume that wastes generated by human explorers are viewed as resources, there is great potential to utilize and recycle them, thereby reducing the requirements for supply Earth and enabling the "live off the land" exploration scenario. Technologies used for the recovery of resources from wastes should be reliable, safe, easy to operate, fail-proof, modular, automated and preferably multifunctional in being capable of handling mixed solid and liquid wastes. For a lunar habitat, energy does not appear to be the major driving factor amongst the technologies studied. Instead, reliability appears to be more important[1] . This paper reports studies to date on drying technologies to remove water from solid wastes and brines. Experimental performance data obtained for recovery water from wastes and brine are presented. Simplicity of operation of hardware and energy efficiency are discussed. Some improvements and modifications to hardware were performed. Hopefully, this information will assist in future efforts in the "downselection" of technologies for recovery of water and resources from solid wastes and brines.

Wignarajah, Kanapathipillai↗

Space Biology in the 21st century

Space Biology is poised to make significant contributions to science in the next century. A carefully crafted, but largely ground-based, program in the United States has evolved major questions that require answers through experiments in space. Science, scientists, and the new long-term spacecrafts designed by NASA will be available for the first time to mount a serious Space Biology effort. The scientific challenge is of such importance that success will provide countless benefits to biologically dependent areas such as medicine, food, and commerce in the decades ahead. The international community is rapidly expanding its role in this field. The United States should generate the resources that will allow progress in Space Biology to match the recognized progress made in aeronautics and the other space sciences.

Halstead, Thora W.↗

Information needs: Perceived and real for state decisionmakers

Remote sensing techniques provide important information for land and water use planning organizations in order to assess coastal developments and their impact on water resources, sediment transport, erosion, and marine biology. Political expediency requires pertinent data acquisition and data dissemination to local populations for coastal zone management decision making.

Schwartz, A. R.↗

Oscillating behavior of carbohydrate granule formation and dinitrogen fixation in the cyanobacterium Cyanothece sp. strain ATCC 51142

It has been shown that some aerobic, unicellular, diazotrophic cyanobacteria temporally separate photosynthetic O2 evolution and oxygen-sensitive N2 fixation. Cyanothece sp. ATCC strain 51142 is an aerobic, unicellular, diazotrophic cyanobacterium that fixes N2 during discrete periods of its cell cycle. When the bacteria are maintained under diurnal light-dark cycles, N2 fixation occurs in the dark. Similar cycling is observed in continuous light, implicating a circadian rhythm. Under N2-fixing conditions, large inclusion granules form between the thylakoid membranes. Maximum granulation, as observed by electron microscopy, occurs before the onset of N2 fixation, and the granules decrease in number during the period of N2 fixation. The granules can be purified from cell homogenates by differential centrifugation. Biochemical analyses of the granules indicate that these structures are primarily carbohydrate, with some protein. Further analyses of the carbohydrate have shown that it is a glucose polymer with some characteristics of glycogen. It is proposed that N2 fixation is driven by energy and reducing power stored in these inclusion granules. Cyanothece sp. strain ATCC 51142 represents an excellent experimental organism for the study of the protective mechanisms of nitrogenase, metabolic events in cyanobacteria under normal and stress conditions, the partitioning of resources between growth and storage, and biological rhythms.

Non-NASA Center↗

Frontier In-Situ Resource Utilization for Enabling Sustained Human Presence on Mars

The currently known resources on Mars are massive, including extensive quantities of water and carbon dioxide and therefore carbon, hydrogen and oxygen for life support, fuels and plastics and much else. The regolith is replete with all manner of minerals. In Situ Resource Utilization (ISRU) applicable frontier technologies include robotics, machine intelligence, nanotechnology, synthetic biology, 3-D printing/additive manufacturing and autonomy. These technologies combined with the vast natural resources should enable serious, pre- and post-human arrival ISRU to greatly increase reliability and safety and reduce cost for human colonization of Mars. Various system-level transportation concepts employing Mars produced fuel would enable Mars resources to evolve into a primary center of trade for the inner solar system for eventually nearly everything required for space faring and colonization. Mars resources and their exploitation via extensive ISRU are the key to a viable, safe and affordable, human presence beyond Earth. The purpose of this paper is four-fold: 1) to highlight the latest discoveries of water, minerals, and other materials on Mars that reshape our thinking about the value and capabilities of Mars ISRU; 2) to summarize the previous literature on Mars ISRU processes, equipment, and approaches; 3) to point to frontier ISRU technologies and approaches that can lead to safe and affordable human missions to Mars; and 4) to suggest an implementation strategy whereby the ISRU elements are phased into the mission campaign over time to enable a sustainable and increasing human presence on Mars.

Moses, Robert W.↗

Lightning NOx Estimates from Space-Based Lightning Imagers

The intense heating of air by a lightning channel, and subsequent rapid cooling, leads to the production of lightning nitrogen oxides (NOx = NO + NO2) as discussed in Chameides [1979]. In turn, the lightning nitrogen oxides (or "LNOx" for brevity) indirectly influences the Earth's climate because the LNOx molecules are important in controlling the concentration of ozone (O3) and hydroxyl radicals (OH) in the atmosphere. Climate is most sensitive to O3 in the upper troposphere, and LNOx is the most important source of NOx in the upper troposphere at tropical and subtropical latitudes; hence, lightning is a useful parameter to monitor for climate assessments. The National Climate Assessment (NCA) program was created in response to the Congressionally-mandated Global Change Research Act (GCRA) of 1990. Thirteen US government organizations participate in the NCA program which examines the effects of global change on the natural environment, human health and welfare, energy production and use, land and water resources, human social systems, transportation, agriculture, and biological diversity. The NCA focuses on natural and human-induced trends in global change, and projects major trends 25 to 100 years out. In support of the NCA, the NASA Marshall Space Flight Center (MSFC) continues to assess lightning-climate inter-relationships. This activity applies a variety of NASA assets to monitor in detail the changes in both the characteristics of ground- and space- based lightning observations as they pertain to changes in climate. In particular, changes in lightning characteristics over the conterminous US (CONUS) continue to be examined by this author using data from the Tropical Rainfall Measuring Mission Lightning Imaging Sensor. In this study, preliminary estimates of LNOx trends derived from TRMM/LIS lightning optical energy observations in the 17 yr period 1998-2014 are provided. This represents an important first step in testing the ability to make remote retrievals of LNOx from a satellite-based lightning sensor. As is shown, the methodology can also be directly applied to more recently launched lightning mappers, such as the Geostationary Lightning Mapper, and the International Space Station LIS.

Koshak, William J.↗

Current NASA Plans for Mars In Situ Resource Utilization

The presentation is to provide relevant information to the NASA funded Center for the Utilization of Biological Engineering in Space (CUBES) Institute. The presentation cover the following: 1) What is In Situ Resource Utilization (ISRU), 2) What are the resources of interest at the Moon and Mars, 3) ISRU-related mission requirements and ISRU economics, 4) Challenges and Risk for ISRU, 5) Concept of Operation for Mars ISRU Systems, 6) Current State of the Art (SOA) in ISRU, and 7) Current ISRU development and mission status.

ISRU↗

Investigation using data from ERTS-1 to develop and implement utilization of living marine resources

The author has identified the following significant results. This 15-month ERTS-1 investigation produced correlations between satellite, aircraft, menhaden fisheries, and environmental sea truth data from the Mississippi Sound. Selected oceanographic, meteorological, and biological parameters were used as indirect indicators of the menhaden resource. Synoptic and near real time sea truth, fishery, satellite imagery, aircraft acquired multispectral, photo and thermal IR information were acquired as data inputs. Computer programs were developed to manipulate these data according to user requirements. Preliminary results indicate a correlation between backscattered light with chlorophyll concentration and water transparency in turbid waters. Eight empirical menhaden distribution models were constructed from combinations of four fisheries-significant oceanographic parameters: water depth, transparency, color, and surface salinity. The models demonstrated their potential for management utilization in areas of resource assessment, prediction, and monitoring.

Stevenson, W. H.↗

Review of wildlife resources of Vandenberg Air Force Base, California

Wildlife resources are reviewed for purposes of developing a Base Biological Monitoring Program (BMP) for Vandenberg Air Force Base (VAFB) in Santa Barbara County, California. The review and recommendations were prepared by review of applicable scientific literature and environmental documents for VAFB, discussing information needs with natural resource management professionals at VAFB, and observations of base field conditions. This process found that there are 29 federally listed vertebrates (endangered, threatened, or Category 2) that occur or may occur in the vicinity of VAFB. There are also 63 other state listed or regionally declining species that may occur in the vicinity of VAFB. Habitats of VAFB represent a very valuable environmental resource for rare and declining wildlife in California. However, little information is available on VAFB wildlife resources other than lists of species that occur or are expected to occur. Recommendations are presented to initiate a long-term wildlife monitoring program at VAFB to provide information for environmental impact assessment and wise land use planning.

Breininger, David R.↗

Open Science for Life in Space

Understanding how biology changes in response spaceflight and how these changes affect crew and craft is important to the design of safe, robust and effective space missions. Advances in analytical technologies allow large volumes of new data to be generated from space biological experiments, and a growing library of legacy data can be re-analyzed in the context of a greater understanding of biological systems. This enables powerful insights into how biology changes during spaceflight. However, for this to be fully realized additional tools, programs, and communities must be developed. Now a developing suite of interconnected open science resources (GeneLab, the Ames Life Sciences Data Archive, the NASA Biological Institutional Science Collection, the Biospecimen Sharing Program) can be leveraged by dedicated Analysis Working Groups to accelerate the pace of discovery in the space biological sciences.

Open Science↗

Plant Leachate Nutrient Recovery with Biological, Thermal, and Photocatalytic Pretreatments

Plants are ideal for long term space travel: provide essential resources - oxygen, water, food; Water-soaked plants expel soluble nutrients in a leachate solution - toxins and wastes are also expelled and inhibit growth; biological, thermal, photocatalytic coupled with an acid digestion treatment will hopefully maximize recovery and remove wastes

Nutrient Recovery↗

Microbial Food Safety in Space Production Systems

While traveling to deep space is difficult for many reasons, food is a crucial one. Round-trip Mars mission scenarios last 3 years, demanding food with a shelf-life of 5 years; this means that feeding human crew sustainably for long-duration missions beyond low Earth orbit (LEO) will ultimately lead to a paradigm shift away from the current Earth-based food production system, which depends upon storing and transporting prepackaged foods, and toward bio-regenerative production of food in space. Pharmaceuticals and nutritional supplements face similar challenges. Moreover, the methods we currently use to detect dangerous microbes in food require sample return to Earth, a situation not viable for deep-space missions. While the science behind generating foods and bioproducts is covered by other white papers, in this paper we discuss a crucial gap uniting all of them: how to ensure that such products are free of unwanted microbial contamination and safe for crew to consume. Because Earth-based food safety systems cannot be directly applied in space, safety assurance is currently a critical bottleneck in the space production of food and other bioproducts. Future sustainable deep-space missions will require NASA to devote more resources in the coming decade to understanding the biological and physical science principles underlying microbial food safety in space, and to developing efficient, reliable methods in this area.

microbiology↗

Source Contaminant Control System Design, Operation, and Testing for the Trash Compaction and Processing System

The Trash Compaction and Processing System (TCPS) aims to reduce volume, biologically safen, physically stabilize, manage effluents, and recover resources from astronaut trash in the International Space Station (ISS). This process involves heating the trash to high temperatures, which in turn releases gaseous contaminants. Effluent management scenarios involve releasing these gases back to the ISS cabin after processing and/or directly venting these gases out to space via the Vacuum Exhaust System (VES). Concerns for recovering the gases back to cabin are crew health, safety, and spacecraft environmental impact. The Heat Melt Compactor (HMC) at NASA Ames Research Center (ARC) serves as a test system that supports TCPS development by conducting risk reduction activities associated with an ISS flight demonstration. Previous gas effluent studies were conducted on the HMC. The results consisted of contaminants from the trash exhaust to exceed Spacecraft Maximum Allowable Concentrations (SMAC), which are selected airborne contaminants that can elicit toxicity symptoms to crewmembers via exposure. The Source Contaminant Control System (SCCS) aims to reduce that risk by converting the contaminants into carbon dioxide (CO2) and water (H2O) vapor. The SCCS is composed of a carbon adsorbent bed, to avoid catalyst poisoning, and a catalytic oxidizer (CatOx), which promotes oxidation of the contaminants to CO2 and H2O. In turn, the gases coming out of the SCCS should be compatible to the ISS cabin and systems such as the Trace Contaminant Control System (TCCS). Preparation for SCCS testing alongside the HMC Gen 3 are currently underway at ARC. The main objectives are to evaluate CatOx efficiency by CO2 conversion and characterize effectiveness of removal by comparing contaminant results before and after CatOx. This paper will report on the SCCS design, operation, and testing with results.

Janine Young↗

Source Contaminant Control System Design, Operation, and Testing for the Trash Compaction and Processing System

The Trash Compaction and Processing System (TCPS) aims to reduce volume, biologically safen, physically stabilize, manage effluents, and recover resources from astronaut trash in the International Space Station (ISS). This process involves heating the trash to high temperatures, which in turn releases gaseous contaminants. Effluent management scenarios involve releasing these gases back to the ISS cabin after processing and/or directly venting these gases out to space via the Vacuum Exhaust System (VES). Concerns for recovering the gases back to cabin are crew health, safety, and spacecraft environmental impact. The Heat Melt Compactor (HMC) at NASA Ames Research Center (ARC) serves as a test system that supports TCPS development by conducting risk reduction activities associated with an ISS flight demonstration. Previous gas effluent studies were conducted on the HMC. The results consisted of contaminants from the trash exhaust to exceed Spacecraft Maximum Allowable Concentrations (SMAC), which are selected airborne contaminants that can elicit toxicity symptoms to crewmembers via exposure. The Source Contaminant Control System (SCCS) aims to reduce that risk by converting the contaminants into carbon dioxide (CO2) and water (H2O) vapor. The SCCS is composed of a carbon adsorbent bed, to avoid catalyst poisoning, and a catalytic oxidizer (CatOx), which promotes oxidation of the contaminants to CO2and H2O. In turn, the gases coming out of the SCCS should be compatible to the ISS cabin and systems such as the Trace Contaminant Control System (TCCS). Preparation for SCCS testing alongside the HMC Gen 3 are currently underway at ARC. The main objectives are to evaluate CatOx efficiency by CO2conversion and characterize effectiveness of removal by comparing contaminant results before and after CatOx. This paper will report on the SCCS design, operation, and testing with results.

TCPS↗

Updated Analysis of the Source Contaminant Control System (SCCS) for the Trash Compaction and Processing System (TCPS)

The Trash Compaction and Processing System (TCPS) aims to reduce volume, biologically safen, physically stabilize, manage effluents, and recover resources from astronaut trash in the International Space Station (ISS). This process involves heating the trash to high temperatures, which in turn releases gaseous contaminants. A Source Contaminant Control System (SCCS) is planned to be implemented within the TCPS to convert these contaminants into carbon dioxide (CO 2 ) and water (H 2 O) vapor. The SCCS is composed of a carbon adsorbent bed, to avoid catalyst poisoning, and a catalytic oxidizer (CatOx), which promotes oxidation of the contaminants to CO 2 and H 2 O. In turn, the gases coming out of the SCCS should be compatible to the ISS cabin and systems such as the Trace Contaminant Control System (TCCS). This paper will individually evaluate the carbon bed and CatOx to understand what components the carbon bed removes and what contaminants are converted in the CatOx. Overall, this is an updated analysis of the SCCS design, operation, testing with results, and lessons learned.

Janine Criselda Young↗