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At least 523 records · Page 29

Morphological Changes in Rat Vestibular System Following Weightlessness

Mammalian gravity receptors (maculas) are morphologically organized for weighted, parallel distributed processing of information. There are two basic circuits: 1) highly channeled, type I cell to calyx; and 2) distributed modifying, type II cells to calyces and processes. The latter circuit should be the more adaptable since it modifies final output. To test this hypothesis, rats were flown in microgravity for 9 days aboard a space shuttle and euthanized shortly after landing. Hair cells and ribbon synapses from maculas of 3 flight and 3 ground control rats were studied ultrastructurally in blocks of 50 serial sections. Synapses increased by approximately 41% in type I cells and by approximately 55% in type II cells in flight animals. There was a shift toward the spherular form of ribbon synapse in both types of hair cells in flight animals. Current findings tend to support the stated hypothesis and indicate that mature utricular hair cells retain synaptic plasticity, permitting adaptation to an altered gravitational environment.

Ross, Muriel D.↗

Integrated Planning for Telepresence with Time Delays

Teleoperation of remote robotic systems over time delays in the range of 2-10 seconds poses a unique set of challenges. In the context of a supervisory control system for the JSC Robonaut humanoid robot, we have developed an 'intelligent assistant' that integrates an Artificial Intelligence planner (JSHOP2) with execution monitoring of the state of both the human supervisor and the remote robot. The assistant reasons simultaneously about the world state on both sides of the time delay, which represents a novel application of this technology. The purpose of the assistant is to provide advice to the human supervisor about current and future activities, derived from a sequence of high-level goals to be achieved. To do this, the assistant must simultaneously monitor and react to various data sources, including actions taken by the supervisor who is issuing commands to the robot (e.g. with a data glove), actions taken by the robot, and the environment of the robot, both as currently perceived over the time delay, along with the current sequence of goals. We have developed a 'leader/follower' software architecture to handle the dual time-shifted streams of execution feedback. In this paper we describe the integrated planner and its executive, and how it operates in normal and anomaly situations.

remote robotic systems↗

PSR J2021+4026 in the Gamma Cygni Region: The First Variable Gamma-Ray Pulsar Seen by the Fermi LAT

Long-term monitoring of PSR J2021+4026 in the heart of the Cygnus region with the Fermi Large Area Telescope unveiled a sudden decrease in flux above 100 MeV over a timescale shorter than a week. The "jump" was near MJD 55850 (2011 October 16), with the flux decreasing from (8.33 plus or minus 0.08)×10(exp −10) erg cm(exp −2) s(exp −1) to (6.86 plus or minus 0.13)× 10 (exp −1)0 erg cm (exp −2) s(exp −1). Simultaneously, the frequency spindown rate increased from (7.8 plus or minus 0.1) × 10(exp −13) Hz s(exp −1) to (8.1 plus or minus 0.1) × 10(exp −1)3 Hz s(exp −1). Significant (greater than 5 sigma) changes in the pulse profile and marginal (less than 3 sigma) changes in the emission spectrum occurred at the same time. There is also evidence for a small, steady flux increase over the 3 yr preceding MJD 55850. This is the first observation at gamma-ray energies of mode changes and intermittent behavior, observed at radio wavelengths for other pulsars. We argue that the change in pulsed gamma-ray emission is due to a change in emission beaming and we speculate that it is precipitated by a shift in the magnetic field structure, leading to a change of either effective magnetic inclination or effective current.

pulsars: individual↗

Proposed Trace Gas Measurements Over the Western United States for TROPOMI Validation

The Alpha Jet Atmospheric eXperiment (AJAX), located in the Bay Area of California, is a joint effort between NASA Ames Research Center and H211, LCC. AJAX makes in-situ airborne measurements of trace gases 2-4 times per month, resulting in over 216 flights since 2011. Current measurements include ozone (O3), carbon dioxide (CO2), methane (CH4), water (H2O), formaldehyde (HCHO), and meteorological measurements (i.e., ambient pressure, temperature, and 3D winds). Currently, the AJAX team is working to incorporate nitrogen dioxide (NO2) measurements with a Cavity Attenuated Phase Shift Spectrometer (CAPS). Successful science flights coincident with satellite overpasses have been performed since 2011 by the Alpha Jet, with more than 40 flights under the Greenhouse Observing SATellite (GOSAT) and several flights under the Orbiting Carbon Observatory-2 (OCO-2). Results from these flights, which have covered a range of different surfaces and seasonal conditions, will be presented. In-situ vertical profiles of O3, CO2, CH4, H2O, HCHO, and NO2 from the surface to 28,000 feet made by AJAX will also be valuable for satellite validation of data products obtained from the TROPOspheric Montoring Instrument (TROPOMI). TROPOMI is on board the Copernicus Sentinel-5 precursor (S5p) satellite, with level 2 products including O3, CO, CH4, HCHO, NO2, and aerosols.

Parworth, Caroline L.↗

PVAnalytics: A Python Package for Automated Processing of Solar Time Series Data

Multiple publicly available software packages exist that analyze solar time series data, including RdTools and Solar Data Tools, among others. Several of these packages contain their own unique quality assurance (QA) and feature recognition algorithms. The python PVAnalytics package was developed to offer an internally consistent source for these analysis tools, making it easier for the end user to deploy these routines on his or her solar data. The PVAnalytics package currently contains routines for outlier detection, inverter clipping detection, irradiance and temperature checks, orientation checks, and data shift detection, among other functions. These functions have been aggregated from various sources including Solar Forecast Arbiter, RdTools, and the QA process developed by NREL's PV Fleets Initiative. We are continuously adding new functionality to the package, including documentation, examples and algorithms. By bundling QA functionality into a single software package, we hope to make PVAnalytics a comprehensive software library to support analysis of solar metadata and time series data.

data cleaning↗

Exploitation of SAR data for measurement of ocean currents and wave velocities

Methods of extracting information on ocean currents and wave orbital velocities from SAR data by an analysis of the Doppler frequency content of the data are discussed. The theory and data analysis methods are discussed, and results are presented for both aircraft and satellite (SEASAT) data sets. A method of measuring the phase velocity of a gravity wave field is also described. This method uses the shift in position of the wave crests on two images generated from the same data set using two separate Doppler bands. Results of the current measurements are pesented for 11 aircraft data sets and 4 SEASAT data sets.

Shuchman, R. A.↗

Particle/fluid simulations of an eruptive flare: Identifying the field-aligned currents responsible for the hard x-rays

While magnetohydrodynamics (MHD) can provide a reasonable description of the overall magnetic reconnection that is believed to drive flares, additional, and often separate processes have to be envoked to in order to explain the electron acceleration that is responsible for many of the observed flare emissions. A new model that incorporates the dynamic coronal current sheets, the reconnection site, and possible electron acceleration processes is developed through the use of two-dimensional particle and modified two-fluid simulations. The specific example of an eruptive flare driven by the coalescence of flux tubes supported by prescribed photospheric current elements is evaluated. It is shown that the electrons and ions have differential trajectories through the coronal current sheet which leads to the development of additonal plasma currents that flow around the surface of the current sheet. These surface currents are explicitly neglected in MHD but they are vital to the flare dynamics because they divert current from the coronal current sheet into the chromosphere, producing an effective resistivity that aids the development of fast reconnection. Because the surface currents are in the plane of the magnetic field, electrons in them experience strong acceleration and can account for the observed hard X-ray emissions. Model predictions are compared with observed time profiles of hard X-ray emissions and Doppler shifts seen in soft X-ray line emissions and are able to account for such features as (1) the asymmetry in the rise and decay time of the hard X-rays, (2) the apparent delay between the largest Doppler shifts and the hard X-ray peak, and (3) the relatively low intensity of the blue-shifted component. The use of particle and fluid simulations is important because it provides different, but complementary treatments of the electron acceleration, the global magnetic morphology, and the flare current system.

Winglee, R. M.↗

UV background fluctuations and three-point correlations in the large-scale clustering of the Lyman α forest

Using the Lyman α (Lyα) Mass Association Scheme, we make theoretical predictions for the three-dimensional three-point correlation function (3PCF) of the Lyα forest at redshift z = 2.3. We bootstrap results from the (100 h -1 Mpc) 3 Horizon hydrodynamic simulation to a (1 h -1 Gpc) 3 N -body simulation, considering both a uniform ultraviolet background (UVB) and a fluctuating UVB sourced by quasars with a comoving n q ≈ 10 -5 h 3 Mpc -3 placed either in massive haloes or randomly. On scales of 10–30 h -1 Mpc, the flux 3PCF displays hierarchical scaling with the square of the two-point correlation function (2PCF), but with an unusual value of Q ≡ ζ 123 /(ξ 12 ξ 13 + ξ 12 ξ 23 + ξ 13 ξ 23 ) ≈ -4.5 that reflects the low bias of the Lyα forest and the anticorrelation between mass density and transmitted flux. For halo-based quasars and an ionizing photon mean free path of λ = 300 h -1 Mpc comoving, UVB fluctuations moderately depress the 2PCF and 3PCF, with cancelling effects on Q . For λ = 100 or 50 h -1 Mpc, UVB fluctuations substantially boost the 2PCF and 3PCF on large scales, shifting the hierarchical ratio to Q ≈ -3. We scale our simulation results to derive rough estimate of the detectability of the 3PCF in current and future observational data sets for the redshift range z = 2.1–2.6. At r = 10 and 20 h -1 Mpc, we predict a signal-to-noise ratio (SNR) of ~9 and ~7, respectively, for both Baryon Oscillation Spectroscopic Survey (BOSS) and extended BOSS (eBOSS), and ~37 and ~25 for Dark Energy Spectroscopic Instrument (DESI). At r = 40 h -1 Mpc the predicted SNR is lower by a factor of ~3–5. Measuring the flux 3PCF would provide a novel test of the conventional paradigm of the Lyα forest and help separate the contributions of UVB fluctuations and density fluctuations to Lyα forest clustering, thereby solidifying its foundation as a tool of precision cosmology.

Astronomy & Astrophysics↗

Investigation of the Effects of Facility Background Pressure on the Performance and Voltage-Current Characteristics of the High Voltage Hall Accelerator

The National Aeronautics and Space Administration (NASA) Science Mission Directorate In-Space Propulsion Technology office is sponsoring NASA Glenn Research Center to develop a 4 kW-class Hall thruster propulsion system for implementation in NASA science missions. A study was conducted to assess the impact of varying the facility background pressure on the High Voltage Hall Accelerator (HiVHAc) thruster performance and voltage-current characteristics. This present study evaluated the HiVHAc thruster performance in the lowest attainable background pressure condition at NASA GRC Vacuum Facility 5 to best simulate space-like conditions. Additional tests were performed at selected thruster operating conditions to investigate and elucidate the underlying physics that change during thruster operation at elevated facility background pressure. Tests were performed at background pressure conditions that are three and ten times higher than the lowest realized background pressure. Results indicated that the thruster discharge specific impulse and efficiency increased with elevated facility background pressure. The voltage-current profiles indicated a narrower stable operating region with increased background pressure. Experimental observations of the thruster operation indicated that increasing the facility background pressure shifted the ionization and acceleration zones upstream towards the thrusters anode. Future tests of the HiVHAc thruster are planned at background pressure conditions that are expected to be two to three times lower than what was achieved during this test campaign. These tests will not only assess the impact of reduced facility background pressure on thruster performance, voltage-current characteristics, and plume properties; but will also attempt to quantify the magnitude of the ionization.

Pressure Effects↗

Climate Shifts Within Major Agricultural Seasons for +1.5 and +2.0 °C Worlds: HAPPI Projections and AgMIP Modeling Scenarios

This study compares climate changes in major agricultural regions and current agricultural seasons associated with global warming of +1.5 or +2.0 °C above pre-industrial conditions. It describes the generation of climate scenarios for agricultural modeling applications conducted as part of the Agricultural Model Intercomparison and Improvement Project (AgMIP) Coordinated Global and Regional Assessments. Climate scenarios from the Half a degree Additional warming, Projections, Prognosis and Impacts project (HAPPI) are largely consistent with transient scenarios extracted from RCP4.5 simulations of the Coupled Model Intercomparison Project phase 5 (CMIP5). Focusing on food and agricultural systems and top-producing breadbaskets in particular, we distinguish maize, rice, wheat, and soy season changes from global annual mean climate changes. Many agricultural regions warm at a rate that is faster than the global mean surface temperature (including oceans) but slower than the mean land surface temperature, leading to regional warming that exceeds 0.5 °C between the +1.5 and +2.0 °C Worlds. Agricultural growing seasons warm at a pace slightly behind the annual temperature trends in most regions, while precipitation increases slightly ahead of the annual rate. Rice cultivation regions show reduced warming as they are concentrated where monsoon rainfall is projected to intensify, although projections are influenced by Asian aerosol loading in climate mitigation scenarios. Compared to CMIP5, HAPPI slightly underestimates the CO2 concentration that corresponds to the +1.5 °C World but overestimates the CO2 concentration for the +2.0 °C World, which means that HAPPI scenarios may also lead to an overestimate in the beneficial effects of CO2 on crops in the +2.0 °C World. HAPPI enables detailed analysis of the shifting distribution of extreme growing season temperatures and precipitation, highlighting widespread increases in extreme heat seasons and heightened skewness toward hot seasons in the tropics. Shifts in the probability of extreme drought seasons generally tracked median precipitation changes; however, some regions skewed toward drought conditions even where median precipitation changes were small. Together, these findings highlight unique seasonal and agricultural region changes in the +1.5 °C and +2.0 °C worlds for adaptation planning in these climate stabilization targets.

Alexander C. Ruane↗

Data for "Soil carbon dynamics during drying vs. rewetting: Importance of antecedent moisture conditions"

This dataset contains data used for the paper "Soil carbon dynamics during drying vs. rewetting: importance of antecedent moisture conditions". The Related References field will be updated with a full citation when available.Soil moisture influences soil carbon dynamics, including microbial growth and respiration. The response of such ‘soil respiration’ to moisture changes is generally assumed to be linear and reversible, i.e. to depend only on the current moisture state. Current models thus do not account for antecedent soil moisture conditions when determining soil respiration or the available substrate pool. We conducted a laboratory incubation to determine how the antecedent conditions of drought and flood influenced soil organic matter (SOM) chemistry, bioavailability, and respiration. We sampled soils from an upland coastal forest, Beaver Creek, WA USA, and subjected them to drying and rewetting treatments. For the drying treatment, field moist soils were saturated and then dried to 75, 50, 35, and 5 % saturation. In the rewetting treatment, field moist soils were air-dried and then rewet to 35, 50, 75, and 100 % saturation. We measured respiration and water extractable organic carbon (WEOC) concentrations and used 1H-NMR and FT-ICR-MS to characterize the WEOC pool across the treatments. The drying vs. wetting treatment strongly influenced SOM bioavailability, as rewet soils (with antecedent drought) had greater WEOC concentrations and respiration fluxes compared to the drying soils (with antecedent flood). In addition, air-dry soils had the highest WEOC concentrations, and the NMR-resolved peaks showed a strong contribution of protein groups in these soils. Both NMR and FT-ICR-MS analyses indicated increased contribution of complex aromatic groups/molecules in the rewet soils, compared to the drying soils. We suggest that drying introduced organic matter into the WEOC pool via desorption of aromatic molecules and/or by microbial cell lysis, and this stimulated microbial mineralization rates. Our work indicates that even short-term shifts in antecedent moisture conditions can strongly influence soil C dynamics at the core scale. The predictive uncertainties in current soil models may be reduced by a more accurate representation of soil water and C persistence that includes a mechanistic and quantitative understanding of the impact of antecedent moisture conditions.This dataset contains a compressed (.zip) archive of the data and R scripts used for this manuscript. The dataset includes files in .csv and .txt format, which can be accessed and processed using MS Excel or R. NMR data are provided as raw output data (accessed in Bruker TopSpin or MestreNova) as well as the MestreNova-processed files. This archive can also be accessed on GitHub at https://github.com/kaizadp/hysteresis_and_soil_carbon (DOI: 10.5281/zenodo.4432885).

1H-NMR↗

Rotor response for transient unbalance changes in a nonlinear simulation

Transient unbalance shifts were determined not to excite a rotor instability in the high pressure turbomachinery of the Space Shuttle Main Engine using the current rotor dynamic models. Sudden unbalance changes of relatively small magnitudes during fast-speed ramps showed stable nonsynchronous motion depending on the resultant unbalance distribution at subsequent high speed dwells. Transient moment unbalance may initiate a limit cycle subsynchronous response that shortly decays, but a persistent subsynchronous with large amplitudes was never achieved. These limit cycle subsynchronous amplitudes appear to be minimized with lower unbalance magnitudes, which indicates improved rotor balancing would sustain synchronous motion only. The transient unbalance phenomenon was determined to be an explanation for synchronous response shifts often observed during engine tests.

Hine, M. J.↗

Blood Pressure Responses and Mineral Ocorticoid Levels in the Suspended Rat Model for Weightlessness

Cardiovascular responses and fluid/electrolyte shifts seen during space flight are attributed to cephalad redistribution of vascular fluid. The antiorthostatic (AO) rat (suspended head down tilted, 15-20 deg) is used to model these responses. Current studies show that elevated blood pressures in A0 rats are sustained for periods up to seven days. Comparisons are made with presuspension rats. Increased blood pressure in head down tilted subjects suggests a specific response to A0 positioning, potentially relatable to cephalad fluid shift. To assess a role for hormonal regulation of sodium excretion, serum aldosterone levels were measured.

Musacchia, X. J.↗

microRNAs (miR 9, 124, 155 and 224) transdifferentiate mouse macrophages to neurons

Highlights: • miR 9, miR 124 and miR155 could reprogramme macrophages to mature neurons. • miR-induced neuronal reprogramming involves stem cell-like intermediate phenotype. • miR 9, miR 124 and miR155 could also reprogramme CD133+ stem cells to mature neurons. Development is an irreversible process of differentiating the undifferentiated cells to functional cells. Brain development involves generation of cells with varied phenotype and functions, which is limited during adulthood, stress, damage/degeneration. Cellular reprogramming makes differentiation reversible process with reprogramming somatic/stem cells to alternative fate with/without stem cells. Exogenously expressed transcription factors or small molecule inhibitors have driven reprogramming of stem/somatic cells to neurons providing alternative approach for pre-clinical/clinical testing and therapeutics. Here in, we report a novel approach of microRNA (miR)- induced trans-differentiation of macrophages (CD11b high) to induced neuronal cells (iNCs) (neuronal markershigh- Nestin, Nurr1, Map2, NSE, Tubb3 and Mash1) without exogenous use of transcription factors. miR 9, 124, 155 and 224 successfully transdifferentiated macrophages to neurons with transient stem cell-like phenotype. We report trans differentiation efficacy 18% and 21% with miR 124 and miR 155. in silico(String 10.0, miR gator, mESAdb, TargetScan 7.0) and experimental analysis indicate that the reprogramming involves alteration of pluripotencygenes like Oct4, Sox2, Klf4, Nanog and pluripotency miR, miR 302. iNCs also shifted to G0 phase indicating manipulation of cell cycle by these miRs. Further, CD133+ intermediate cells obtained during current protocol could be differentiated to iNCs using miRs. The syanpsin{sup +} neurons were functionally active and displayed intracellular Ca{sup +2} evoke on activation. miRs could also transdifferentiate bone marrow-derived macrophages and peripheral blood mononuclear cells to neuronal cells. The current protocol could be employed for direct in vivo reprogramming of macrophages to neurons without teratoma formation for transplantation and clinical studies.

60 APPLIED LIFE SCIENCES↗

Response of Banded Whistler Mode Waves to the Enhancement of Solar Wind Dynamic Pressure in the Inner Earth's Magnetosphere

With observations of Van Allen Probe A, in this letter we display a typical event where banded whistler waves shifted up their frequencies with frequency bands broadening as a response to the enhancement of solar wind dynamic pressure. Meanwhile, the anisotropy of electrons with energies about several tens of keV was observed to increase. Through the comparison of the calculated wave growth rates and observed wave spectral intensity, we suggest that those banded whistler waves observed with frequencies shifted up and frequency bands broadening could be locally excited by these hot electrons with increased anisotropy. The current study provides a great in situ evidence for the influence on frequencies of banded whistler waves by the enhancement of solar wind dynamic pressures, which reveals the important role of solar wind dynamic pressures playing in the frequency properties of banded whistler waves.

79 ASTRONOMY AND ASTROPHYSICS↗

Abiotic selection of microbial genome size in the global ocean

Abstract Strong purifying selection is considered a major evolutionary force behind small microbial genomes in the resource-poor photic ocean. However, very little is currently known about how the size of prokaryotic genomes evolves in the global ocean and whether patterns reflect shifts in resource availability in the epipelagic and relatively stable deep-sea environmental conditions. Using 364 marine microbial metagenomes, we investigate how the average genome size of uncultured planktonic prokaryotes varies across the tropical and polar oceans to the hadal realm. We find that genome size is highest in the perennially cold polar ocean, reflecting elongation of coding genes and gene dosage effects due to duplications in the interior ocean microbiome. Moreover, the rate of change in genome size due to temperature is 16-fold higher than with depth up to 200 m. Our results demonstrate how environmental factors can influence marine microbial genome size selection and ecological strategies of the microbiome.

59 BASIC BIOLOGICAL SCIENCES↗

Characterization of thin CdTe solar cells with a CdSeTe front layer

Thin CdTe photovoltaic device efficiencies show significant improvement with the incorporation of a CdSeTe alloy layer deposited between a MgZnO emitter and CdTe absorber. CdTe and CdSeTe/CdTe devices fabricated by close-space sublimation with a total absorber thickness of 1.5 µm are studied using microscopy measurements and show minimal diffusion of Se into the CdTe. Current loss analysis shows that the CdSeTe layer is the primary absorber in the CdSeTe/CdTe structure, and fill factor loss analysis shows that ideality-factor reduction is the dominant mechanism of fill factor loss. Improvement in the CdSeTe/CdTe absorber quality compared to CdTe is also reflected in spectral and time-resolved photoluminescence measurements. Current density vs. voltage measurements show an increase in current density of up to 2 mA/cm 2 with the addition of CdSeTe due to a band gap shift from 1.5 to 1.42 eV for CdTe and CdSeTe/CdTe absorbers respectively. Voltage deficit is lower with the incorporation of the CdSeTe layer, corroborated by improved electroluminescence intensity. Here, the addition of CdSeTe into CdTe device structures has increased device efficiencies from 14.7% to 15.6% for absorbers with a total thickness less than two microns.

14 SOLAR ENERGY↗