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Mars Sample Quarantine Protocol Workshop

The Mars Sample Quarantine Protocol (QP) Workshop was convened to deal with three specific aspects of the initial handling of a returned Mars sample: 1) biocontainment, to prevent uncontrolled release of sample material into the terrestrial environment; 2) life detection, to examine the sample for evidence of live organisms; and 3) biohazard testing, to determine if the sample poses any threat to terrestrial life forms and the Earth's biosphere. During the first part of the Workshop, several tutorials were presented on topics related to the workshop in order to give all participants a common basis in the technical areas necessary to achieve the objectives of the Workshop.

DeVincenzi, Donald L.↗

Lay and Expert Perceptions of Planetary Protection

As space scientists and engineers plan new missions to Mars and other planets in our solar system, they will face critical questions about the potential for biological contamination of planetary surfaces. In a society that places ever-increasing importance on the role of public involvement in science and technology policy, questions about risks of biological contamination will be examined and debated in the media, and will lead to the formation of public perceptions of planetary-contamination risks. These perceptions will, over time, form an important input to the development of space policy. Previous research in public and expert perceptions of technological risks and hazards has shown that many of the problems faced by risk-management organizations are the result of differing perceptions of risk (and risk management) between the general public and scientific and technical experts. These differences manifest themselves both as disagreements about the definition (and level) of risk associated with a scientific, technological or industrial enterprise, and as distrust about the ability of risk-management organizations (both public and private) to adequately protect people's health and safety. This report presents the results of a set of survey studies designed to reveal perceptions of planetary exploration and protection from a wide range of respondents, including both members of the general public and experts in the life sciences. The potential value of this research lies in what it reveals about perceptions of risk and benefit that could improve risk-management policies and practices. For example, efforts to communicate with the public about Mars sample return missions could benefit from an understanding of the specific concerns that nonscientists have about such a mission by suggesting areas of potential improvement in public education and information. Assessment of both public and expert perceptions of risk can also be used to provide an advanced signal of aspects of planetary exploration and protection that may be particularly sensitive or controversial and that could prove problematic from a risk-management standpoint, perhaps warranting a more stringent risk-management approach than would otherwise be the case based on technical considerations alone. The design of the study compares perceptions and attitudes about space exploration relevant to a Mars sample return mission between three respondent groups: (1) members of The Planetary Society, a group representing individuals with a strong interest in space-related issues, (2) a group of university-aged students, representing a population relatively sensitive to environmental hazards, and (3) a group of life scientists outside of the space research community. Members of The Planetary Society received the survey as part of a special issue of The Planetary Report on planetary protection, which contained a number of background articles on planetary protection and related topics. A synopsis of the issue was prepared as an introduction to the survey for the other two groups.

Race, Margaret S.↗

Reconsidering the Theological and Ethical Implications of Extraterrestrial Life

As we stand on the threshold of a new millennium, we also find ourselves at the brink of a new and exciting era in space exploration. In fact, this new era has already begun, with the successful landing and exploration of Mars by the Pathfinder mission in July 1997. Pathfinder represents an important scientific accomplishment for NASA because it demonstrated the agency's ability to successfully explore space at a relatively modest price. At the same time, Pathfinder revealed once again the genuine interest and fascination that people all over planet Earth have for space exploration. The recent Pathfinder mission to Mars was only the first in an ambitious series of NASA missions planned for exploration of Mars, Earth's nearest planetary neighbor where extraterrestrial life is a real possibility. In March 1998, the next step in this exploration takes place, when the Mars Global Surveyor--which is already in orbit around Mars--begins photographing and mapping the Martian surface. NASA plans to continue its exploration with additional landers and orbiters taking off for Mars every 26 months, when the paths of Mars and Earth bring them in closer proximity. By the year 2005, NASA hopes to launch a mission that will return martian samples to Earth. And, as early as 2011, astronauts could be rocketing from Earth for the first human landing on the Red Planet. In the distant future, there may be even more grandiose plans, including the possibility of engineering an atmosphere on Mars that could support biological life.

Randolph, Richard O.↗

Planetary Protection, Sample Return Missions and Mars Exploration: History, Status, and Future Needs

As the prospect grows for a Mars sample return mission early in the next millennium, it will be important to ensure that appropriate planetary protection (PP) controls are incorporated into the mission design and implementation from the start. The need for these PP controls is firmly based on scientific considerations and backed by a number of national and international agreements and guidelines aimed at preventing harmful cross contamination of planets and extraterrestrial bodies. The historical precedent for the use of PP measures on both unmanned and manned missions traces from post-Sputnik missions to the present, with periodic modifications as new information was obtained. In consideration of the anticipated attention to PP questions by both the scientific/technical community and the public, this paper presents a comprehensive review of the major issues and problems surrounding PP for a Mars Sample Return (MSR) mission, including an analysis of arguments that have been raised for and against the imposition of PP measures. Also discussed are the history and foundations for PP policies and requirements; important research areas needing attention prior to defining detailed PP requirements for a MSR mission; and legal and public awareness issues that must be considered with mission planning.

DeVincenzi, Donald L.↗

Mars Sample Handling Protocol Workshop Series

This document is the report resulting from the first workshop of the series on development of the criteria for a Mars sample handling protocol. Workshop 1 was held in Bethesda, Maryland on March 20-22, 2000. This report serves to document the proceedings of Workshop 1; it summarizes relevant background information, provides an overview of the deliberations to date, and helps frame issues that will need further attention or resolution in upcoming workshops. Specific recommendations are not part of this report.

Rummel, John D.↗

Bring'em Back Alive or at Least Carefully

Within the next decade, the world's space agencies plan to launch a variety of robotic spacecraft that will return samples from the surface of Mars, the tail of a comet, the nucleus of a comet, the surface of an asteroid, and the solar wind. Most of these places are not considered likely spots for life, but any mission returning from a location with the potential for harboring life will require special containment and handling because of the possible inclusion of living entities within returned samples. In its 1997 report on sample return from Mars, the Space Studies Board of the National Research Council (NRC) noted that the only risk of significant adverse effects would be from returning a replicating organism. Furthermore, the report noted: 'While the probability of returning a replicating biological entity in a sample from Mars' is judged to be low and the risk of pathogenic or ecological effects is lower still, the risk is not zero. Therefore, it is reasonable that NASA adopt a prudent approach, erring on the side of caution and safety when dealing with returned samples. More recently, a 1998 NRC report on small solar system bodies (asteroids, comets, planetary satellites, and interplanetary dust) recommended a similarly cautious approach for samples returned from anywhere else within the solar system that could have environmental conditions conducive for harboring life. We have not detected life elsewhere in the solar system, at least not yet. Nonetheless, the rationale behind the conservative approach to sample handling is similar to the environmental, health, and safety measures taken on Earth when transporting or handling infectious agents or importing non-native organisms to a new area. Better safe than sorry.

Race, Margaret S.↗

Integrating Public Perspectives in Sample Return Planning

Planning for extraterrestrial sample returns, whether from Mars or other solar system bodies, must be done in a way that integrates planetary protection concerns with the usual mission technical and scientific considerations. Understanding and addressing legitimate societal concerns about the possible risks of sample return will be a critical part of the public decision making process ahead. This paper presents the results of two studies, one with lay audiences, the other with expert microbiologists, designed to gather information, on attitudes and concerns about sample return risks and planetary protection. Focus group interviews with lay subjects, using generic information about Mars sample return and a preliminary environmental impact assessment, were designed to obtain an indication of how the factual content is perceived and understood by the public. A research survey of microbiologists gathered information on experts' views and attitudes about sample return, risk management approaches and space exploration risks. These findings, combined with earlier research results on risk perception, will be useful in identifying levels of concern and potential conflicts in understanding between experts and the public about sample return risks. The information will be helpful in guiding development of the environmental impact statement and also has applicability to proposals for sample return from other solar system bodies where scientific uncertainty about extraterrestrial life may persist at the time of mission planning.

Race, Margaret S.↗

Planetary Protection, Sample Return Missions and Mars Exploration: History, Status, and Future Needs

As the prospect grows for a Mars sample return mission early in the next millennium, it will be important to ensure that appropriate planetary protection (PP) controls are incorporated into the mission design and implementation from the start. The need for these PP controls is firmly based on scientific considerations and backed by a number of national and international agreements and guidelines aimed at preventing harmful cross contamination of planets and extraterrestrial bodies. The historical precedent for the use of PP measures on both unmanned and manned missions traces from post-Sputnik missions to the present, with periodic modifications as new information was obtained. In consideration of the anticipated attention to PP questions by both the scientific/technical community and the public, this paper presents a comprehensive review of the major issues and problems surrounding PP for a Mars Sample Return (MSR) mission, including an analysis of arguments that have been raised for and against the imposition of PP measures. Also discussed are the history and foundations for PP policies and requirements; important research areas needing attention prior to defining detailed PP requirements for a MSR mission; and legal and public awareness issues that must be considered with mission planning.

DeVincenzi, Donald L.↗

Reconsidering the Theological and Ethical Implications of Extraterrestrial Life

As we stand on the threshold of a new millennium, we also find ourselves at the brink of a new and exciting era in space exploration. In fact, this new era has already begun, with the successful landing and exploration of Mars by the Pathfinder mission in July 1997. Pathfinder represents an important scientific accomplishment for NASA because it demonstrated the agency's ability to successfully explore space at a relatively modest price. At the same time, Pathfinder revealed once again the genuine interest and fascination that people all over planet Earth have for space exploration. The Pathfinder mission is just one of several recent events-both scientific and cultural-that reveal this deep and almost unquenchable curiosity about space-and the possibility that there is life "out there." In August 1996, the public was captivated with NASA's announcement that a meteorite from Mars may contain evidence of early microscopic life. Shortly after the NASA announcement, media coverage of the discovery-and public discourse concerning the discovery-turned to an examination of the theological implications of evidence for extraterrestrial, albeit unintelligent, life. To a lesser extent, public reaction to the Hale-Bopp comet in the Spring of 1996 is also suggestive of many persons' deep passion to know more about space.

Randolph, Richard O.↗

Mars Sample Handling Protocol Workshop Series: Workshop 2

Numerous NASA reports and studies have identified Planetary Protection (PP) as an important part of any Mars sample return mission. The mission architecture, hardware, on-board experiments, and related activities must be designed in ways that prevent both forward- and back-contamination and also ensure maximal return of scientific information. A key element of any PP effort for sample return missions is the development of guidelines for containment and analysis of returned sample(s). As part of that effort, NASA and the Space Studies Board (SSB) of the National Research Council (NRC) have each assembled experts from a wide range of scientific fields to identify and discuss issues pertinent to sample return. In 1997, the SSB released its report on recommendations for handling and testing of returned Mars samples. In particular, the NRC recommended that: a) samples returned from Mars by spacecraft should be contained and treated as potentially hazardous until proven otherwise, and b) rigorous physical, chemical, and biological analyses [should] confirm that there is no indication of the presence of any exogenous biological entity. Also in 1997, a Mars Sample Quarantine Protocol workshop was convened at NASA Ames Research Center to deal with three specific aspects of the initial handling of a returned Mars sample: 1) biocontainment, to prevent 'uncontrolled release' of sample material into the terrestrial environment; 2) life detection, to examine the sample for evidence of organisms; and 3) biohazard testing, to determine if the sample poses any threat to terrestrial life forms and the Earth's biosphere. In 1999, a study by NASA's Mars Sample Handling and Requirements Panel (MSHARP) addressed three other specific areas in anticipation of returning samples from Mars: 1) sample collection and transport back to Earth; 2) certification of the samples as non-hazardous; and 3) sample receiving, curation, and distribution. To further refine the requirements for sample hazard testing and the criteria for subsequent release of sample materials from quarantine, the NASA Planetary Protection Officer convened an additional series of workshops beginning in March 2000. The overall objective of these workshops was to develop comprehensive protocols to assess whether the returned materials contain any biological hazards, and to safeguard the purity of the samples from possible terrestrial contamination. This document is the report of the second Workshop in the Series. The information herein will ultimately be integrated into a final document reporting the proceedings of the entire Workshop Series along with additional information and recommendations.

Rummel, John D.↗

Mars Sample Handling Protocol Workshop Series

This report provides a record of the proceedings and recommendations of Workshop 3 of the Series, which was held in San Diego, California, March 19-21, 2001. Materials such as the Workshop agenda and participant lists as well as complete citations of all references and a glossary of terms and acronyms appear in the Appendices. Workshop 3 builds on the deliberations and findings of the earlier workshops in the Series, which have been reported separately. During Workshop 3, five individual sub-groups were formed to discuss the following topics: (1) Unifying Properties of Life, (2) Morphological organization and chemical properties, (3) Geochemical and geophysical properties, (4) Chemical Method and (5) Cell Biology Methods.

Race, Margaret S.↗

A Draft Protocol for Detecting Possible Biohazards in Martian Samples Returned to Earth

In preparation for missions to Mars that will involve the return of samples, it is necessary to prepare for the safe receiving, handling, testing, distributing, and archiving of martian materials here on Earth. Previous groups and committees have studied selected aspects of sample return activities, but a specific protocol for handling and testing of returned -=1 samples from Mars remained to be developed. To refine the requirements for Mars sample hazard testing and to develop criteria for the subsequent release of sample materials from precautionary containment, NASA Planetary Protection Officer, working in collaboration with CNES, convened a series of workshops to produce a Protocol by which returned martian sample materials could be assessed for biological hazards and examined for evidence of life (extant or extinct), while safeguarding the samples from possible terrestrial contamination. The Draft Protocol was then reviewed by an Oversight and Review Committee formed specifically for that purpose and composed of senior scientists. In order to preserve the scientific value of returned martian samples under safe conditions, while avoiding false indications of life within the samples, the Sample Receiving Facility (SRF) is required to allow handling and processing of the Mars samples to prevent their terrestrial contamination while maintaining strict biological containment. It is anticipated that samples will be able to be shipped among appropriate containment facilities wherever necessary, under procedures developed in cooperation with international appropriate institutions. The SRF will need to provide different types of laboratory environments for carrying out, beyond sample description and curation, the various aspects of the protocol: Physical/Chemical analysis, Life Detection testing, and Biohazard testing. The main principle of these tests will be described and the criteria for release will be discussed, as well as the requirements for the SRF and its personnel.

Viso, M.↗

A Draft Test Protocol for Detecting Possible Biohazards in Martian Samples Returned to Earth

This document presents the first complete draft of a protocol for detecting possible biohazards in Mars samples returned to Earth; it is the final product of the Mars Sample Handling Protocol Workshop Series, convened in 2000-2001 by NASA's Planetary Protection Officer. The goal of the five-workshop Series vas to develop a comprehensive protocol by which returned Martian sample materials could be assessed for the presence of any biological hazard(s) while safeguarding the purity of the samples from possible terrestrial contamination The reference numbers for the proceedings from the five individual Workshops.

John D. Rummel↗

Anticipating the reaction: public concern about sample return missions

Shifts in public attitude that may affect extraterrestrial sample return include increased public participation in the legal and regulatory environment, institutionalized public vigilance, politicization of technological debates and shifts in the nature of public decision-making, and a risk-averse public accustomed to mass media coverage that focuses on hazards and disasters. The ice-minus recombinant DNA experiment is used as an example of the effects of public opinion on scientific experimentation.

NASA Center ARC↗

Planetary protection, legal ambiguity and the decision making process for Mars sample return

As scientists and mission planners develop planetary protection requirements for future Mars sample return missions, they must recognize the socio-political context in which decisions about the mission will be made and pay careful attention to public concerns about potential back contamination of Earth. To the extent that planetary protection questions are unresolved or unaddressed at the time of an actual mission, they offer convenient footholds for public challenges in both legal and decision making realms, over which NASA will have little direct control. In this paper, two particular non-scientific areas of special concern are discussed in detail: 1) legal issues and 2) the decision making process. Understanding these areas is critical for addressing legitimate public concerns as well as for fulfilling procedural requirements regardless whether sample return evokes public controversy. Legal issues with the potential to complicate future missions include: procedural review under National Environmental Policy Act (NEPA); uncertainty about institutional control and authority; conflicting regulations and overlapping jurisdictions; questions about international treaty obligations and large scale impacts; uncertanities about the nature of the organism; and constitutional and regulatory concerns about quarantine, public health and safety. In light of these important legal issues, it is critical that NASA consider the role and timing of public involvement in the decision making process as a way of anticipating problem areas and preparing for legitimate public questions and challenges to sample return missions.

NASA Discipline Number 59-10↗

Influence of Planetary Protection Guidelines on Waste Management Operations

Newly outlined missions in the Space Exploration Initiative include extended human habitation on Mars. During these missions, large amounts of waste materials will be generated in solid, liquid and gaseous form. Returning these wastes to Earth will be extremely costly, and will therefore likely remain on Mars. Untreated, these wastes are a reservoir of live/dead organisms and molecules considered to be "biomarkers" i.e., indicators of life). If released to the planetary surface, these materials can potentially confound exobiology experiments and disrupt Martian ecology indefinitely (if existent). Waste management systems must therefore be specifically designed to control release of problematic materials both during the active phase of the mission, and for any specified post-mission duration. To effectively develop waste management requirements for Mars missions, planetary protection guidelines must first be established. While previous policies for Apollo lunar missions exist, it is anticipated that the increased probability of finding evidence of life on Mars, as well as the lengthy mission durations will initially lead to more conservative planetary protection measures. To facilitate the development of overall requirements for both waste management and planetary protection for future missions, a workshop was conducted to identify how these two areas interface, and to establish a preliminary set of planetary protection guidelines that address waste management operations. This paper provides background regarding past and current planetary protection and waste management issues, and their interactions. A summary of the recommended planetary protection guidelines, anticipated ramifications and research needs for waste management system design for both forward (Mars) and backward (Earth) contamination is also provided.

Hogan, John A.↗