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At least 505 records · Page 28

THE TURBULENT ORIGIN OF OUTFLOW AND SPIN MISALIGNMENT IN MULTIPLE STAR SYSTEMS

The protostellar outflows of wide-separation forming binaries frequently appear misaligned. We use magneto-hydrodynamic simulations to investigate the alignment of protostellar spin and molecular outflows for forming binary pairs. We show that the protostellar pairs, which form from turbulent fragmentation within a single parent core, have randomly oriented angular momentum. Although the pairs migrate to closer separations, their spins remain partially misaligned. We produce {sup 12}CO(2-1) synthetic observations of the simulations and characterize the outflow orientation in the emission maps. The CO-identified outflows exhibit a similar random distribution and are also statistically consistent with the observed distribution of molecular outflows. We conclude that the observed misalignment provides a clear signature of binary formation via turbulent fragmentation. The persistence of misaligned outflows and stellar spins following dynamical evolution may provide a signature of binary origins for more evolved multiple star systems.

79 ASTRONOMY AND ASTROPHYSICS↗

Modeling the Observed Solar Cycle Variations of the Quasi-biennial Oscillation (QBO): Amplification by Wave Forcing

In several papers, the solar cycle (SC) effect in the lower atmosphere has been linked observationally to the Quasi-biennial Oscillation (QBO) of the zonal circulation, which is generated primarily by small-scale gravity waves (GW). Salby and Callaghan (2000) in particular analyzed the QBO, covering more than 40 years, and discovered that it contains a large SC signature at 20 km. With our Numerical Spectral Model (NSM), we conducted a 3D study to describe the QBO under the influence of the SC, and some results have been published (Mayr et al., GRL, 2005,2006). For a SC period of 10 years, the relative amplitude of radiative forcing is taken to vary exponentially with height, i.e., 0.2% at the surface, 2% at 50 km, 20% at 100 km and above. Applying spectral analysis to filter out and identify the SC signature, the model generates a relatively large modulation of the QBO, which reproduces the observations qualitatively. Our numerical results demonstrate that the modulation of the QBO, with constant phase relative to the SC, persist at least for 60 years. The same model run generates in the seasonal variations a hemispherically symmetric Equatorial Annual Oscillation (EAO, with 12-month period), which is confined to low latitudes like the QBO and is also modulated by the SC. Although the amplitude of the EAO is relatively small, its SC modulation is large, and it is in phase with that of the QBO. The SC modulated EAO is evidently the pathway and pacemaker for the solar influence on the QBO. To shed light on the dynamical processes involved, we present model results that show how the seasonal cycle induces the SC modulations of the EAO and QBO. Our analysis further demonstrates that the SC modulations of the QBO and EAO are amplified by the GW interaction with the flow. The GW momentum source clearly shows a SC modulation that is in phase with the corresponding modulations of the QBO and EAO. By tapping the momentum from the upward propagating GWs, the QBO and EAO apparently serve as conduits to amplify and transfer to lower altitudes the larger SC variations in the UV absorbed in the mesosphere. Our model also produces in the temperature variations of the QBO and EAO measurable SC modulations at polar latitudes near the tropopause, and such signatures have been reported in the literature. Contrary to conventional interpretation, however, we suggest that the effects are generated at least in part by the meridional circulation, and planetary waves presumably, which redistribute the energy from the equatorial region where wave forcing is very efficient and thereby amplifies the SC influence.

Mayr, Hans G.↗

Adaptive Modal Identification for Flutter Suppression Control

In this paper, we will develop an adaptive modal identification method for identifying the frequencies and damping of a flutter mode based on model-reference adaptive control (MRAC) and least-squares methods. The least-squares parameter estimation will achieve parameter convergence in the presence of persistent excitation whereas the MRAC parameter estimation does not guarantee parameter convergence. Two adaptive flutter suppression control approaches are developed: one based on MRAC and the other based on the least-squares method. The MRAC flutter suppression control is designed as an integral part of the parameter estimation where the feedback signal is used to estimate the modal information. On the other hand, the separation principle of control and estimation is applied to the least-squares method. The least-squares modal identification is used to perform parameter estimation.

Aeroelasticity↗

An Empirical Model of Radiation Belt Electron Pitch Angle Distributions Based On Van Allen Probes Measurements

Based on over 4 years of Van Allen Probes measurements, an empirical model of radiation belt electron equatorial pitch angle distribution (PAD) is constructed. The model, developed by fitting electron PADs with Legendre polynomials, provides the statistical PADs as a function of L-shell (L = 1-6), magnetic local time, electron energy (~30 keV to 5.2 MeV), and geomagnetic activity (represented by the Dst index) and is also the first empirical PAD model in the inner belt and slot region. For megaelectron volt electrons, model results show more significant day-night PAD asymmetry of electrons with higher energies and during disturbed times, which is caused by geomagnetic field configuration and flux radial gradient changes. Steeper PADs with higher fluxes around 90° pitch angle and lower fluxes at lower pitch angles for higher energy electrons and during active times are also present, which could be due to electromagnetic ion cyclotron wave scattering. For hundreds of kiloelectron volt electrons, cap PADs are generally present in the slot region during quiet times and their energy-dependent features are consistent with hiss wave scattering, while during active times, cap PADs are less significant especially at outer part of slot region, which could be due to the complex energizing and transport processes. The 90°-minimum PADs are persistently present in the inner belt and appear in the slot region during active times, and minima at 90° pitch angle are more significant for electrons with higher energies, which could be a critical evidence in identifying the underlying physical processes responsible for the formation of 90°-minimum PADs.

Zhao, H.↗

Randomized control trial of moderate dose vitamin D alters microbiota stability and metabolite networks in healthy adults

ABSTRACT Evidence indicates that both vitamin D and the gut microbiome are involved in the process of colon carcinogenesis. However, it is unclear what effects supplemental vitamin D 3 has on the gut microbiome and its metabolites in healthy adults. We conducted a double-blind, randomized, placebo-controlled trial to identify the acute and long-term microbiota structural and metabolite changes that occur in response to a moderate dose (4,000 IU) of vitamin D 3 for 12 weeks in healthy adults. Our results demonstrated a significant increase in serum 25-hydroxy-vitamin D (25(OH)D) in the treatment group compared to placebo ( P < 0.0001). Vitamin D 3 significantly increased compositional similarity ( P < 0.0001) in the treatment group, and enriched members of the Bifidobacteriaceae family. We also identified a significant inverse relationship between the percent change in serum 25(OH)D and microbial stability in the treatment group ( R = −0.52, P < 0.019). Furthermore, vitamin D 3 supplementation resulted in notable metabolic shifts, in addition to resulting in a drastic rewiring of key gut microbial-metabolic associations. In conclusion, we show that a moderate dose of vitamin D 3 among healthy adults has unique acute and persistent effects on the fecal microbiota, and suggest novel mechanisms by which vitamin D may affect the host-microbiota relationship. IMPORTANCE Preventative measures to reduce the rise in early-onset colorectal cancer are of critical need. Both vitamin D, dietary and serum levels, and the gut microbiome are implicated in the etiology of colorectal cancer. By understanding the intimate relationship between vitamin D, the gut microbiome, and its metabolites, we may be able to identify key mechanisms that can be targeted for intervention, including inflammation and metabolic dysfunction. Furthermore, the similarity of vitamin D to cholesterol, which is metabolized by the gut microbiome, gives precedence to its ability to produce metabolites that can be further studied and leveraged for controlling colorectal cancer incidence and mortality.

Wyatt, Madhur↗

“It’s Raining Bits”: Patterns in Directional Precipitation Persistence Across the United States

The spatial and temporal ordering of precipitation occurrence impacts ecosystems, streamflow, and water availability. For example, both large-scale climate patterns and local landscapes drive weather events, and the typical speeds and directions of these events moving across a basin dictate the timing of flows at its outlet. We address the predictability of precipitation occurrence at a given location, based on the knowledge of past precipitation at surrounding locations. We identify ‘‘dominant directions of precipitation influence’’ across the continental United States based on a gridded daily dataset. Specifically, we apply information theory–based measures that characterize dominant directions and strengths of spatial and temporal precipitation dependencies. On a national average, this dominant direction agrees with the prevalent direction of weather movement from west to east across the country, but regional differences reflect topographic divides, precipitation gradients, and different climatic drivers of precipitation. Trends in these information relationships and their correlations with climate indices over the past 70 years also show seasonal and spatial divides. This study expands upon a framework of information-based predictability to answer questions about spatial connectivity in addition to temporal persistence. The methods presented here are generally useful to understand many aspects of weather and climate variability.

North America↗

NuSTAR HARD X-RAY SURVEY OF THE GALACTIC CENTER REGION. II. X-RAY POINT SOURCES

We present the first survey results of hard X-ray point sources in the Galactic Center (GC) region by NuSTAR. We have discovered 70 hard (3–79 keV) X-ray point sources in a 0.6 deg 2 region around Sgr A* with a total exposure of 1.7 Ms, and 7 sources in the Sgr B2 field with 300 ks. We identify clear Chandra counterparts for 58 NuSTAR sources and assign candidate counterparts for the remaining 19. The NuSTAR survey reaches X-ray luminosities of ~4x and ~8 x 10 32 erg s -1 at the GC (8 kpc) in the 3–10 and 10–40 keV bands, respectively. The source list includes three persistent luminous X-ray binaries (XBs) and the likely run-away pulsar called the Cannonball. New source-detection significance maps reveal a cluster of hard (>10 keV) X-ray sources near the Sgr A diffuse complex with no clear soft X-ray counterparts. The severe extinction observed in the Chandra spectra indicates that all the NuSTAR sources are in the central bulge or are of extragalactic origin. Spectral analysis of relatively bright NuSTAR sources suggests that magnetic cataclysmic variables constitute a large fraction (>40%–60%). Both spectral analysis and logN–logS distributions of the NuSTAR sources indicate that the X-ray spectra of the NuSTAR sources should have kT > 20 keV on average for a single temperature thermal plasma model or an average photon index of Γ = 1.5–2 for a power-law model. These findings suggest that the GC X-ray source population may contain a larger fraction of XBs with high plasma temperatures than the field population.

79 ASTRONOMY AND ASTROPHYSICS↗

Anastomosing hemangioma of the liver: a case series

Purpose: To report imaging and pathologic features of five pathologically proven anastomosing hemangiomas of the liver (AHL). Methods: A retrospective review for AHL was conducted using our institutional database from 6/2004 to 3/2018. Histology proven AHL with radiologic imaging available for review were included. A total of five patients who met our criteria were identified from our institutional database. Computed tomography, ultrasound, and magnetic resonance imaging findings, including location, size, attenuation/signal intensity, enhancement characteristics, and additional imaging data were reviewed. The clinical and pathological data were also reviewed. Results: The imaging characteristics of AHL are variable, but features such as peripheral or diffuse hyperintensity on diffusion weighted imaging, arterial hyperenhancement without globular interrupted enhancement, and persistent enhancement without complete filling in the delayed phases were more characteristic of AHL. Imaging also demonstrated a lack of aggressive features. Conclusions: AHL present a diagnostic dilemma as they can mimic more malignant lesions, such as angiosarcoma, both on imaging and at pathology. While the imaging characteristics of AHL are variable, there are some features which can help distinguish AHL from other liver lesions. When the diagnosis of anastomosing hemangioma is known, the management of choice is primarily surveillance, as intervention can cause unnecessary morbidity, and no degeneration to malignancy has been identified to date.

62 RADIOLOGY AND NUCLEAR MEDICINE↗

BLOOD-BASED MULTI-SCALE MODEL FOR CANCER RISK FROM GCR IN GENETICALLY DIVERSE POPULATIONS

OBJECTIVES AND METHODS This project addresses the challenge of understanding and predicting individual radiation sensitivity by integrating genetics, demographics and biomarker characteristics across species (mice and humans). We hypothesize that ex vivo DNA repair response to GCR components is a central determinant of cancer risk from space radiation and can serve as a biomarker of radiation risk in combination with genetics. Automated image quantification of 53BP1+ radiation-induced foci (RIF) during the first 4-48 h post-irradiation was performed as a function of dose and LET in non-immortalized primary skin fibroblasts derived from 76 mice across 15 strains (5 inbred reference strains and 10 collaborative-cross strains) exposed to X rays (0.1, 1 and 4 Gy), 350 MeV/n 40Ar and 600 MeV/n 56Fe (1.1 and 3 particles/100μm2), as well as in peripheral blood mononuclear cells (PBMCs) from 768 healthy donors (matched ethnicity, 50/50 male/female, 18-70 years old) exposed to gamma rays (0.1 and 1 Gy), 350 MeV/n 28Si, 350 MeV/n 40Ar and 600 MeV/n 56Fe (1.1 and 3 particles/100μm2). QUANTIFICATION OF 53BP1+ FOCI IN VITRO AND ASSOCIATIONS TO IN VIVO RADIATION SUSCEPTIBILITY IN 15 MOUSE STRAINS We reported in vitro repair kinetic and repairable fractions of RIF for the 15 mouse strains and introduced a mathematical model for RIF as a function of time, dose and LET. We noted that the metabolic activity of cells modulates the RIF response, and we introduced the open access tool terRIFic (Tool for Enhanced Results of RIF In Cells, https://radbiolab.shinyapps.io/terrific/) to correct for such bias using confluence level. Notably, at 4h post-irradiation, RIF/Gy decreased with dose or LET: as the dose or LET increases, so does the proximity of DNA double-strand-breaks (DSB) and our data suggest that proximal DSBs are brought together inside isolated RIF for repair. The RIF/Gy trend was inverted at 24h, suggesting RIF with high DSB content are more difficult to repair. We showed that in vitro metrics correlate with in vivo measurements in the same 15 mouse strains, such as survival levels of immune cells or spontaneous cancer incidence, suggesting a relationship between the efficiency of DSB repair and cancer risk or radiation toxicity. In addition to the efficiency of repair and persistent RIF, the amount of spontaneous foci before irradiation was also found to be strain dependent. Finally, we performed genome-wide association study in the same 15 mouse strains using all RIF phenotypes measured in vitro, identifying genes of interest and validating RIF as an ideal biomarker for individual radiation sensitivity. BASELINE 53BP1+ FOCI PREDICTS INDIVIDUAL HUMAN RESPONSE TO GCR COMPONENTS Based on the analysis of radiation responses of 576 donor PBMCs (using quantification of 53BP1+ foci, oxidative stress and cell death), we observed a wide variability of subject- and LET-dependent radiation responses, with radiation-induced DNA repair foci increasing with LET, though oxidative stress being notably reduced by high-LET irradiation, potentially due to a switch between hydrogen peroxide and oxygen radical-based mechanisms. We identified a relationship between few spontaneous DNA foci at baseline and increased DNA repair after irradiation, accompanied by an alteration in immunoregulatory cytokine secretion, which might be adapted as biomarkers to predict ionizing radiation sensitivity. Among demographic variables, only latent cytomegalovirus infection and age were predictive of high baseline foci formation. Finally, we have performed low-throughput whole genome sequencing of all samples and are currently in the process of identifying the genes and pathways associated with low and high-LET ionizing radiation sensitivity in humans.

53BP1↗

KMT-2021-BLG-1150Lb: Microlensing Planet Detected Through a Densely Covered Planetary-Caustic Signal

Aims. Recently, there have been reports of various types of degeneracies in the interpretation of planetary signals induced by planetary caustics. In this work we check whether such degeneracies persist in the case of well-covered signals by analyzing the lensing event KMT-2021-BLG-1150, the light curve of which exhibits a densely and continuously covered short-term anomaly. Methods. In order to identify degenerate solutions, we thoroughly investigated the parameter space by conducting dense grid searches for the lensing parameters. We then checked the severity of the degeneracy among the identified solutions. Results. We identify a pair of planetary solutions resulting from the well-known inner-outer degeneracy, and find that interpreting the anomaly is not subject to any degeneracy other than the inner-outer degeneracy. The measured parameters of the planet separation (normalized to the Einstein radius) and mass ratio between the lens components are ( s , q ) in ∼ (1.297, 1.10 × 10 −3 ) for the inner solution and ( s , q ) out ∼ (1.242, 1.15 × 10 −3 ) for the outer solution. According to a Bayesian estimation, the lens is a planetary system consisting of a planet with a mass M p = 0.88 +0.38 −0.36 M J and its host with a mass M h = 0.73 +0.32 −0.30 M ⊙ lying toward the Galactic center at a distance D L = 3.8 +1.3 −1.2 kpc. By conducting analyses using mock data sets prepared to mimic those obtained with data gaps and under various observational cadences, we find that gaps in data can result in various degenerate solutions, while the observational cadence does not pose a serious degeneracy problem as long as the anomaly feature can be delineated.

Gravitational microlensing↗

Beyond Binary: Automated PLC Memory Forensics through RGB Image Analysis and Deep Learning

The introduction of Industry 4.0 and the evolution of industrial control systems (ICS) to adopt Internet-based technologies enhanced productivity, but have inadvertently increased their vulnerability to cyber-based malicious attacks. When an ICS system is compromised, security analysts need to identify the root cause quickly to start the recovery process and develop mitigation strategies to safeguard against future instances. Memory forensics is critical in the analysis process to ascertain what occurred. To date, approaches to analyze the persistent memory in ICS devices are limited, and almost nonexistent for volatile memory. This paper proposes an automated methodology, COMA, for PLC memory dump analysis using computer vision and deep learning techniques. Specifically, COMA converts the sequences of bytes in a PLC memory dump to RGB pixels and creates a deep learning model that learns the underlying patterns and features of pre-labeled forensic artifacts in images and segments them into distinct regions. COMA then uses the trained model to automatically segment new memory images and extract forensic artifacts. We evaluate COMA on a Schneider Electric Modicon M221 PLC involving two cyber-based attack scenarios: (i) code injection and (ii) code modification. The empirical results show that COMA can successfully detect attack artifacts in memory dumps in both scenarios.

Asmar Awad, Rima↗

Improvements to sample processing and measurement to enable more widespread environmental application of tritium

Previous measurements have demonstrated the wealth of information that tritium (T) can provide on environmentally relevant processes. We present modifications to sample preparation approaches that enable T measurement by proportional counting on small sample sizes equivalent to 120 mg of water and demonstrate the accuracy of these methods on a suite of standardized water samples. This enhanced method should provide the analytical flexibility needed to address persistent knowledge gaps in our understanding of T behavior in the environment.

low background↗

Likelihood of Bone Recurrence in Prior Sites of Metastasis in Patients With High-Risk Neuroblastoma

Purpose/Objectives: Despite recent improvements in outcomes, 40% of children with high-risk neuroblastoma will experience relapse, facing a guarded prognosis for long-term cure. Whether recurrences are at new sites or sites of original disease may guide decision making during initial therapy. Methods and Materials: Eligible patients were retrospectively identified from institutional databases at first metastatic relapse of high-risk neuroblastoma. Included patients had disease involving metaiodobenzylguanidine (MIBG)-avid metastatic sites at diagnosis and first relapse, achieved a complete or partial response with no more than one residual MIBG-avid site before first relapse, and received no total body irradiation or therapy with {sup 131}I-MIBG before first relapse. Anatomically defined metastatic sites were tracked from diagnosis through first relapse to determine tendency of disease to recur at previously involved versus uninvolved sites and to assess whether this pattern was influenced by site irradiation. Results: Of 159 MIBG-avid metastatic sites identified among 43 patients at first relapse, 131 (82.4%) overlapped anatomically with the set of 525 sites present at diagnosis. This distribution was similar for bone sites, but patterns of relapse were more varied for the smaller subset of soft tissue metastases. Among all metastatic sites at diagnosis in our subsequently relapsed patient cohort, only 3 of 19 irradiated sites (15.8%) recurred as compared with 128 of 506 (25.3%) unirradiated sites. Conclusions: Metastatic bone relapse in neuroblastoma usually occurs at anatomic sites of previous disease. Metastatic sites identified at diagnosis that did not receive radiation during frontline therapy appeared to have a higher risk of involvement at first relapse relative to previously irradiated metastatic sites. These observations support the current paradigm of irradiating metastases that persist after induction chemotherapy in high-risk patients. Furthermore, they raise the hypothesis that metastatic sites appearing to clear with induction chemotherapy may also benefit from radiotherapeutic treatment modalities (external beam radiation or {sup 131}I-MIBG)

62 RADIOLOGY AND NUCLEAR MEDICINE↗

Spatial Heterogenous Redox Couples Degradation in Sodium-Ion Battery Cathode Materials and the Mitigation of Voltage Fade by Blocking Oxygen Release

The use of anionic redox has become a new paradigm for improving the energy density of rechargeable batteries, which is essential for improving the market competitiveness of sodium-ion batteries. However, issues such as voltage attenuation and cycling stability degradation persist in layered oxide anion redox cathode materials. Here, in this study, we systematically investigate the classic Na-ion cathode material Na 0.6 Li 0.2 Mn 0.8 O 2 , and the primary causes of voltage decay are identified as the activation of cations and the reduction in anion redox activity. In addition, the activation of cations is closely associated with anion reactions. Through the application of sophisticated multiscale synchrotron absorption spectroscopy and imaging techniques, we have identified a pronounced pattern of spatially dependent degradation in the evolution of redox couples, which is more evident from the material’s surface to its core. With this understanding, we introduced a surface fluorination approach that modulates the local chemical coordination environment. This strategy increases the formation energy of surface oxygen vacancies and locks transition metals oxide state. Consequently, it enables more reversible anionic redox reactions, which block the spatial progression of degradation and mitigates voltage decay.

25 ENERGY STORAGE↗

Early Cardiac Mitochondrial Molecular and Functional Responses to Acute Anthracycline Treatment in Wistar Rats

Abstract Doxorubicin (DOX) is an anticancer drug widely used to treat human and nonhuman tumors but the late and persistent cardio-toxicity reduces the therapeutic utility of the drug. The full mechanism(s) of DOX-induced acute, subchronic and delayed toxicity, which has a preponderant mitochondrial component, remains unclear; therefore, it is clinically relevant to identify early markers to identify patients who are predisposed to DOX-related cardiovascular toxicity. To address this, Wistar rats (16 weeks old) were treated with a single DOX dose (20 mg/kg, i.p.); then, mRNA, protein levels and functional analysis of mitochondrial endpoints were assessed 24 h later in the heart, liver, and kidney. Using an exploratory data analysis, we observed cardiac-specific alterations after DOX treatment for mitochondrial complexes III, IV, and preferentially for complex I. Conversely, the same analysis revealed complex II alterations are associated with DOX response in the liver and kidney. Interestingly, H2O2 production by the mitochondrial respiratory chain as well as loss of calcium-loading capacity, markers of subchronic toxicity, were not reliable indicators of acute DOX cardiotoxicity in this animal model. By using sequential principal component analysis and feature correlation analysis, we demonstrated for the first time alterations in sets of transcripts and proteins, but not functional measurements, that might serve as potential early acute markers of cardiac-specific mitochondrial toxicity, contributing to explain the trajectory of DOX cardiac toxicity and to develop novel interventions to minimize DOX cardiac liabilities.

Pereira, Gonçalo C.↗

Coronal holes and high-speed wind streams

Coronal holes, regions of unusually low density and low temperature in the solar corona, are identified as Bartel's M regions, i.e., sources of high-speed wind streams that produce recurrent geomagnetic variations. Throughout the Skylab period the polar caps of the sun were coronal holes, and at lower latitudes the most persistent and recurrent holes were equatorial extensions of the polar caps. The holes rotated 'rigidly' at the equatorial synodic rate. They formed in regions of unipolar photospheric magnetic field, and their internal magnetic fields diverged rapidly with increasing distance from the sun. The geometry of the magnetic field in the inner corona seems to control both the physical properties of the holes and the global distribution of high-speed wind streams in the heliosphere. Phenomenological models for the birth and decay of coronal holes have been proposed.

Zirker, J. B.↗

Introgression and persistence of cultivar alleles in wild carrot ( Daucus carota ) populations in the United States

Abstract Premise Cultivated species and their wild relatives often hybridize in the wild, and the hybrids can survive and reproduce in some environments. However, it is unclear whether cultivar alleles are permanently incorporated into the wild genomes or whether they are purged by natural selection. This question is key to accurately assessing the risk of escape and spread of cultivar genes into wild populations. Methods We used genomic data and population genomic methods to study hybridization and introgression between cultivated and wild carrot (Daucus carota) in the United States. We used single nucleotide polymorphisms (SNPs) obtained via genotyping by sequencing for 450 wild individuals from 29 wild georeferenced populations in seven states and 144 cultivars from the United States, Europe, and Asia. Results Cultivated and wild carrot formed two genetically differentiated groups, and evidence of crop–wild admixture was detected in several but not all wild carrot populations in the United States. Two regions were identified where cultivar alleles were present in wild carrots: California and Nantucket Island (Massachusetts). Surprisingly, there was no evidence of introgression in some populations with a long‐known history of sympatry with the crop, suggesting that post‐hybridization barriers might prevent introgression in some areas. Conclusions Our results provide support for the introgression and long‐term persistence of cultivar alleles in wild carrots populations. We thus anticipate that the release of genetically engineered (GE) cultivars would lead to the introduction and spread of GE alleles in wild carrot populations.

Plant Sciences↗

Persistent Heavy Winter Nitrate Pollution Driven by Increased Photochemical Oxidants in Northern China

Nitrate is an increasingly important component of fine particulate matter (PM2.5) during winter in northern China. Past emission control has been ineffective in reducing winter nitrate. Here, we use extensive observations and a model with state-of-theart nitrogen chemistry to identify the key factors that control the nitrate formation in the heavily polluted North China Plain (NCP). In contrast to the previous view of weak winter photochemistry, we show that the O3 and OH productions are sufficiently high in winter to facilitate fast gas-phase and heterogeneous conversion of NOX to nitrate over the NCP. Increasing O3 and OH productions from higher precursor levels and fast ROX cycling accelerate the nitrate generation during heavy pollution. We find that the 31.8% reduction of NOX emissions from 2010 to 2017 in the NCP lowers surface nitrate by only 0.2% and even increases nitrate in some polluted areas. This is mainly due to the increase of O3 and OH (by~30%), which has subsequently increased the conversion efficiency of NOX to HNO3 (by 38.7%). Future control strategies for the winter haze should also aim to lower photochemical oxidants, via larger and synchronized NOX and VOCs emissions reduction, to overcome the effects of nonlinear photochemistry and aerosol chemical feedback.

Fu, Xiao↗