Engineering Papers⌕ Search

SEARCH · Engineering Papers

Results for “MINIMIZATION”

Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 505 records · Page 28

Numerical minimization of neoclassical poloidal viscosity for supersonic equilibria in tokamak geometry

Extensive experimental evidence has shown that the presence of poloidal flow in tokamaks can dramatically improve transport properties. However, theory indicates that poloidal flows are damped by poloidal viscosity, thus necessitating external drivers, such as neutral beam injection or radio frequency heating. In this work, ideal magnetohydrodynamic equilibria are calculated via the FORTRAN code FLOW [Guazzotto et al., Phys. Plasmas 11, 604 (2004)] and a postprocessor is used to estimate the neoclassical poloidal viscosity. The equilibrium inputs, which correspond to intuitive physical quantities, are then numerically optimized to reduce a viscosity figure of merit. We present supersonic equilibria in tokamak geometry with minimized neoclassical poloidal viscosities for various velocity free function inputs, plasma aspect ratios, and collisionality regimes. Benchmarks are made against an analytic theory as well as a classical expression of poloidal viscosity. Numerical confirmation of the analytic theory is obtained in the high aspect ratio and high collisionality limit. Good agreement is also seen near the plasma core and edge, with discrepancies arising in the intermediate region. Outside of these limits, rotation input function profiles are found that provide ∼order of magnitude improvements over the analytic theory, with additional progress being made toward predictions for tokamak-relevant equilibria.

Physics↗

Banach spaces that realize minimal fillings

It is proved that a real Banach space realizes minimal fillings for all its finite subsets (a shortest network spanning a fixed finite subset always exists and has the minimum possible length) if and only if it is a predual of L{sub 1}. The spaces L{sub 1} are characterized in terms of Steiner points (medians). Bibliography: 25 titles. (paper)

97 MATHEMATICS AND COMPUTING↗

Bioavailable soil Pb minimized by in situ transformation to plumbojarosite

Exposure to lead (Pb) during early life has persistent adverse health effects. During childhood, ingestion of bioavailable Pb in contaminated soils can be a major route of Pb absorption. Remediation to alter physiochemical properties of soil-borne Pb can reduce Pb bioavailability. Our laboratory-based approach for soil Pb remediation uses addition of iron (Fe) sulfate and application of heat to promote formation of plumbojarosite (PLJ), a sparingly soluble Pb-Fe hydroxysulfate mineral. We treated two soils with anthropogenic Pb contamination and samples of clean topsoil spiked with various Pb compounds (i.e., carbonate, chloride, phosphate [P], or sulfate) to convert native Pb species to PLJ and used a mouse assay to assess relative bioavailability (RBA) of Pb in untreated (U) and remediated soils. Bone and blood Pb levels were significantly lower (P < 0.001, Student's t test) in mice that consumed diets amended with remediated soils than with U soils. Estimated RBA for Pb in both remediated natural soils and Pb-mineral spiked soils were reduced by >90% relative to Pb RBA for U soils, which is substantially more effective than other soil amendments, including P. X-ray absorption spectroscopy showed that >90% of all Pb species in remediated soils were converted to PLJ, and ingested PLJ was not chemically transformed during gastrointestinal tract transit. Post treatment neutralization of soil pH did not affect PLJ stability, indicating the feasibility in field conditions. These results suggest that formation of PLJ in contaminated soils can reduce the RBA of Pb and minimize this medium’s role as a source of Pb exposure for young children.

59 BASIC BIOLOGICAL SCIENCES↗

Minimizing the impacts of the ammonia economy on the nitrogen cycle and climate

Ammonia (NH 3 ) is an attractive low-carbon fuel and hydrogen carrier. However, losses and inefficiencies across the value chain could result in reactive nitrogen emissions (NH 3 , NO x , and N 2 O), negatively impacting air quality, the environment, human health, and climate. A relatively robust ammonia economy (30 EJ/y) could perturb the global nitrogen cycle by up to 65 Mt/y with a 5% nitrogen loss rate, equivalent to 50% of the current global perturbation caused by fertilizers. Moreover, the emission rate of nitrous oxide (N 2 O), a potent greenhouse gas and ozone-depleting molecule, determines whether ammonia combustion has a greenhouse footprint comparable to renewable energy sources or higher than coal (100 to 1,400 gCO 2 e/kWh). The success of the ammonia economy hence hinges on adopting optimal practices and technologies that minimize reactive nitrogen emissions. We discuss how this constraint should be included in the ongoing broad engineering research to reduce environmental concerns and prevent the lock-in of high-leakage practices.

54 ENVIRONMENTAL SCIENCES↗

Mechanism-guided engineering of a minimal biological particle for genome editing

The widespread application of genome editing to treat and cure disease requires the delivery of genome editors into the nucleus of target cells. Enveloped delivery vehicles (EDVs) are engineered virally derived particles capable of packaging and delivering CRISPR-Cas9 ribonucleoproteins (RNPs). However, the presence of lentiviral genome encapsulation and replication proteins in EDVs has obscured the underlying delivery mechanism and precluded particle optimization. Here, we show that Cas9 RNP nuclear delivery is independent of the native lentiviral capsid structure. Instead, EDV-mediated genome editing activity corresponds directly to the number of nuclear localization sequences on the Cas9 enzyme. EDV structural analysis using cryo-electron tomography and small molecule inhibitors guided the removal of ~80% of viral residues, creating a minimal EDV (miniEDV) that retains full RNP delivery capability. MiniEDVs are 25% smaller yet package equivalent amounts of Cas9 RNPs relative to the original EDVs and demonstrated increased editing in cell lines and therapeutically relevant primary human T cells. These results show that virally derived particles can be streamlined to create efficacious genome editing delivery vehicles with simpler production and manufacturing.

59 BASIC BIOLOGICAL SCIENCES↗

A minimal complex of KHNYN and zinc-finger antiviral protein binds and degrades single-stranded RNA

Detecting viral infection is a key role of the innate immune system. The genomes of some RNA viruses have a high CpG dinucleotide content relative to most vertebrate cell RNAs, making CpGs a molecular marker of infection. The human zinc-finger antiviral protein (ZAP) recognizes CpG, mediates clearance of the foreign CpG-rich RNA, and causes attenuation of CpG-rich RNA viruses. While ZAP binds RNA, it lacks enzymatic activity that might be responsible for RNA degradation and thus requires interacting cofactors for its function. One of these cofactors, KHNYN, has a predicted nuclease domain. Using biochemical approaches, we found that the KHNYN NYN domain is a single-stranded RNA ribonuclease that does not have sequence specificity and digests RNA with or without CpG dinucleotides equivalently in vitro. We show that unlike most KH domains, the KHNYN KH domain does not bind RNA. Indeed, a crystal structure of the KH region revealed a double-KH domain with a negatively charged surface that accounts for the lack of RNA binding. Rather, the KHNYN C-terminal domain (CTD) interacts with the ZAP RNA-binding domain (RBD) to provide target RNA specificity. We define a minimal complex composed of the ZAP RBD and the KHNYN NYN-CTD and use a fluorescence polarization assay to propose a model for how this complex interacts with a CpG dinucleotide-containing RNA. In the context of the cell, this module would represent the minimum ZAP and KHNYN domains required for CpG-recognition and ribonuclease activity essential for attenuation of viruses with clusters of CpG dinucleotides.

Yeoh, Zoe C. (ORCID:0000000226949068)↗

Sequential Selection for Minimizing the Variance with Application to Crystallization Experiments

For many crystal-based products (e.g., pharmaceuticals, energy storage), the size uniformity is not only a key quality attribute, but sometimes also an indicator of other attributes such as solid purity. This article proposes a sequential selection approach to find a proper experimental setting that leads to high uniformity, or equivalently, small variance for crystal sizes, from the advanced slug flow reaction crystallization process of a model crystal, called manganese oxalate hydrate. The proposed sequential selection approach contains a Bayesian adaptive method to incorporate new uniformity measurements in each step and two design acquisition functions to improve the selection of the most promising experimental setting in terms of minimizing the variance. We study the performance of the proposed approach through multiple synthetic numerical studies, as well as a case study based on data from slug flow crystallization experiments. Throughout these studies, the proposed approach shows competitive performance in identifying the best experimental setting.

Expected improvement↗

Generating synthetic magnetic field intermittency using a Minimal Multiscale Lagrangian Mapping approach

The Minimal Multiscale Lagrangian Mapping procedure developed in the context of neutral fluid turbulence is a simple method for generating synthetic vector fields. Using a sequence of low-pass filtered fields, fluid particles are displaced at their rms speed for some scale-dependent time interval, and then interpolated back to a regular grid. Fields produced in this way are seen to possess certain properties of real turbulence. This paper extends the technique to plasmas by taking into account the coupling between the velocity and magnetic fields. We examine several possible applications to plasma systems. One use is as initial conditions for simulations, wherein these synthetic fields may efficiently produce a strongly intermittent cascade. The intermittency properties of the synthetic fields are also compared with those of the solar wind. Finally, studies of cosmic ray transport and modulation in the test particle approximation may benefit from improved realism in synthetic fields produced in this way.

79 ASTRONOMY AND ASTROPHYSICS↗

2D dilaton-gravity, deformations of the minimal string, and matrix models

A large class of two-dimensional dilaton-gravity theories in asymptotically AdS2 spacetimes are holographically dual to a matrix integral, interpreted as an ensemble average over Hamiltonians. Viewing these theories as Jackiw–Teitelboim gravity with a gas of defects, we extend this duality to a broader class of dilaton potentials compared to previous work by including conical defects with small deficit angles. In order to do this we show that these theories are equal to the large p limit of a natural deformation of the (2, p) minimal string theory.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗

The Gutzwiller conjugate gradient minimization method for correlated electron systems

In this report we review our recent work on the Gutzwiller conjugate gradient minimization method, an ab initio approach developed for correlated electron systems. The complete formalism has been outlined that allows for a systematic understanding of the method, followed by a discussion of benchmark studies of dimers, one- and two-dimensional single-band Hubbard models. In the end, we present some preliminary results of multi-band Hubbard models and large-basis calculations of F 2 to illustrate our efforts to further reduce the computational complexity.

75 CONDENSED MATTER PHYSICS, SUPERCONDUCTIVITY AND↗

Minimizing separatrix crossings through isoprominence

Abstract A simple property of magnetic fields that minimizes bouncing to passing type transitions of guiding center orbits is defined and discussed. This property, called isoprominence, is explored through the framework of a near-axis expansion. It is shown that isoprominent magnetic fields for a toroidal configuration exist to all orders in a formal expansion about a magnetic axis. Some key geometric features of these fields are described.

confinement↗

On the Vainshtein mechanism in the minimal model of massive gravity

We reinvestigate the fate of the Vainhstein mechanism in the minimal model of dRGT massive gravity. As the latter is characterised by the complete absence of interactions in the decoupling limit, we study their structure at higher energies. We show that in static spherically symmetric configurations, the lowest energy scale of interactions is pushed up to the Planck mass. This fact points towards an absence of Vainshtein mechanism in this framework, but does not prove it. By resorting to the exact vacuum equations of motion, we show that there is indeed an obstruction that precludes any recovery of General Relativity under the conditions of stationarity and spherical symmetry. However, we argue that the latter are too restrictive and might miss some important physical phenomena. Indeed, we point out that in generic non spherically symmetric or time-dependent situations, interactions arising at energies arbitrarily close to the energy scale of the decoupling limit reappear. This leads us to question whether the small degree of spherical symmetry breaking in the solar system can be sufficient to give rise to a successful Vainshtein mechanism.

79 ASTRONOMY AND ASTROPHYSICS↗

Dark matter in the minimal inverse seesaw mechanism

We consider the possibility of simultaneously addressing the dark matter problem and neutrino mass generation in the minimal inverse seesaw realisation. The Standard Model is extended by two right-handed neutrinos and three sterile fermionic states, leading to three light active neutrino mass eigenstates, two pairs of (heavy) pseudo-Dirac mass eigenstates and one (mostly) sterile state with mass around the keV, possibly providing a dark matter candidate, and accounting for the recently observed and still unidentified monochromatic 3.5 keV line in galaxy cluster spectra. The conventional production mechanism through oscillation from active neutrinos can account only for ∼ 43% of the observed relic density. This can be slightly increased to ∼ 48% when including effects of entropy injection from the decay of light (with mass below 20 GeV) pseudo-Dirac neutrinos. The correct relic density can be achieved through freeze-in from the decay of heavy (above the Higgs mass) pseudo-Dirac neutrinos. This production is only effective for a limited range of masses, such that the decay occurs not too far from the electroweak phase transition. We thus propose a simple extension of the inverse seesaw framework, with an extra scalar singlet coupling to both the Higgs and the sterile neutrinos, which allows to achieve the correct dark matter abundance in a broader region of the parameter space, in particular in the low mass region for the pseudo-Dirac neutrinos.

79 ASTRONOMY AND ASTROPHYSICS↗

LHC prospects for minimal decaying dark matter

We study the possible signals at LHC of the minimal models of decaying dark matter. Those models are characterized by the fact that DM interacts with SM particles through renormalizable coupling with an additional heavier charged state. Such interaction allows to produce a substantial abundance of DM in the early Universe via the decay of the charged heavy state, either in- or out-of-equilibrium. Moreover additional couplings of the charged particle open up decay channels for the DM, which can nevertheless be sufficiently long-lived to be a good DM candidate and within reach of future Indirect Detection observations. We compare the cosmologically favored parameter regions to the LHC discovery reach and discuss the possibility of simultaneous detection of DM decay in Indirect Detection.

79 ASTRONOMY AND ASTROPHYSICS↗

Wormholes minimally violating the null energy condition

We consider novel wormhole solutions supported by a matter content that minimally violates the null energy condition. More specifically, we consider an equation of state in which the sum of the energy density and radial pressure is proportional to a constant with a value smaller than that of the inverse area characterising the system, i.e., the area of the wormhole mouth. This approach is motivated by a recently proposed cosmological event, denoted {sup t}he little sibling of the big rip{sup ,} where the Hubble rate and the scale factor blow up but the cosmic derivative of the Hubble rate does not [1]. By using the cut-and-paste approach, we match interior spherically symmetric wormhole solutions to an exterior Schwarzschild geometry, and analyse the stability of the thin-shell to linearized spherically symmetric perturbations around static solutions, by choosing suitable properties for the exotic material residing on the junction interface radius. Furthermore, we also consider an inhomogeneous generalization of the equation of state considered above and analyse the respective stability regions. In particular, we obtain a specific wormhole solution with an asymptotic behaviour corresponding to a global monopole.

79 ASTRONOMY AND ASTROPHYSICS↗

Superradiance and black hole bomb in five-dimensional minimal ungauged supergravity

We examine the black hole bomb model which consists of a rotating black hole of five-dimenensional minimal ungauged supergravity and a reflecting mirror around it. For low-frequency scalar perturbations, we find solutions to the Klein-Gordon equation in the near-horizon and far regions of the black hole spacetime. To avoid solutions with logarithmic terms, we assume that the orbital quantum number l takes on nearly, but not exactly, integer values and perform the matching of these solutions in an intermediate region. This allows us to calculate analytically the frequency spectrum of quasinormal modes, taking the limits as l approaches even or odd integers separately. We find that all l modes of scalar perturbations undergo negative damping in the regime of superradiance, resulting in exponential growth of their amplitudes. Thus, the model under consideration would exhibit the superradiant instability, eventually behaving as a black hole bomb in five dimensions.

79 ASTRONOMY AND ASTROPHYSICS↗

Chaotic inflation limits for non-minimal models with a Starobinsky attractor

We investigate inflationary attractor points by analysing non-minimally coupled single field inflation models in two opposite limits; the 'flat' limit in which the first derivative of the conformal factor is small and the 'steep' limit, in which the first derivative of the conformal factor is large. We consider a subset of models that yield Starobinsky inflation in the steep conformal factor, strong coupling, limit and demonstrate that they result in φ{sup 2n}-chaotic inflation in the opposite flat, weak coupling, limit. The suppression of higher order powers of the inflaton field in the potential is shown to be related to the flatness condition on the conformal factor. We stress that the chaotic attractor behaviour in the weak coupling limit is of a different, less universal, character than the Starobinsky attractor. Agreement with the COBE normalisation cannot be obtained in both attractor limits at the same time and in the chaotic attractor limit the scale of inflation depends on the details of the conformal factor, contrary to the strong coupling Starobinsky attractor.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗