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At least 487 records · Page 27

A statistical model of diurnal variation in human growth hormone

The diurnal pattern of growth hormone (GH) serum levels depends on the frequency and amplitude of GH secretory events, the kinetics of GH infusion into and clearance from the circulation, and the feedback of GH on its secretion. We present a two-dimensional linear differential equation model based on these physiological principles to describe GH diurnal patterns. The model characterizes the onset times of the secretory events, the secretory event amplitudes, as well as the infusion, clearance, and feedback half-lives of GH. We illustrate the model by using maximum likelihood methods to fit it to GH measurements collected in 12 normal, healthy women during 8 h of scheduled sleep and a 16-h circadian constant-routine protocol. We assess the importance of the model components by using parameter standard error estimates and Akaike's Information Criterion. During sleep, both the median infusion and clearance half-life estimates were 13.8 min, and the median number of secretory events was 2. During the constant routine, the median infusion half-life estimate was 12.6 min, the median clearance half-life estimate was 11.7 min, and the median number of secretory events was 5. The infusion and clearance half-life estimates and the number of secretory events are consistent with current published reports. Our model gave an excellent fit to each GH data series. Our analysis paradigm suggests an approach to decomposing GH diurnal patterns that can be used to characterize the physiological properties of this hormone under normal and pathological conditions.

Non-NASA Center↗

Continuous liquid level measurements with time domain reflectometry

A time domain reflectometer is considered as a closed loop, one-dimensional radar system. Applying the principle of time domain reflectometry to the detection of cryogenic liquid levels, measurements on the order of + or - 0. 3% of total liquid level probe length are possible. The time domain reflectometer liquid level measurement is independent of liquid density variations and is simple to calibrate and operate. Construction of the liquid level sensing probe is described.

Cruz, J. E.↗

Directional reflectance factor distributions for cover types of Northern Africa

Directional reflectance factors that spanned the entire exitance hemisphere were collected on the ground throughout the morning period for common cover types in Tunisia, Africa. NOAA 7/8 AVHRR bands 1(0.58-0.68 micron) and 2 (0.7301.1 micron) were used in data collection. The cover types reported were a plowed field, annual grassland, steppe grassland, hard wheat, salt plain, and irrigated wheat. Several of these cover types had geometric structures that are extreme as compared to those reported in the literature. Comparisons were made between the dynamics of the observed reflectance distributions and those reported in the literature. It was found that the dynamics of the measured data could be explained by a combination of soil and vegetation scattering components. The data and analysis further validated physical principles that cause the reflectance distribution dynamics as proposed by field and simulation studies in the literature. Finally, the normalized difference transformation (Band 2 - Band 1)/(Band 1 + Band 2), which is useful in monitoring vegetation cover, generally decreased the variation in signal with changing view angle. However, several exceptions were noted.

Kimes, D. S.↗

Land-surface temperature measurement from space - Physical principles and inverse modeling

To apply the multiple-wavelength (split-window) method used for satellite measurement of sea-surface temperature from thermal-infrared data to land-surface temperatures, the authors statistically analyze simulations using an atmospheric radiative transfer model. The range of atmospheric conditions and surface temperatures simulated is wide enough to cover variations in clear atmospheric properties and surface temperatures, both of which are larger over land than over sea. Surface elevation is also included in the simulation as the most important topographic effect. Land covers characterized by measured or modeled spectral emissivities include snow, clay, sands, and tree leaf samples. The empirical inverse model can estimate the surface temperature with a standard deviation less than 0.3 K and a maximum error less than 1 K, for viewing angles up to 40 degrees from nadir under cloud-free conditions, given satellite measurements in three infrared channels. A band in the region from 10.2 to 11.0 microns will usually give the most reliable single-band estimate of surface temperature. In addition, a band in either the 3.5-4.0-micron region or in the 11.5-12.6-micron region must be included for accurate atmospheric correction, and a band below the ozone absorption feature at 9.6 microns (e.g., 8.2-8.8 microns) will increase the accuracy of the estimate of surface temperature.

Wan, Zhengming↗

Deflections of anisotropic sandwich beams with variable face sheets and core thicknesses

A sandwich construction consists of a low-density core material with high strength face sheets bounded to the top and bottom surfaces. The construction has been widely used in the aerospace and marine industries due to its outstanding characteristics such as noise absorption, weight minimization, heat insulation, and better bending stiffness. In sandwich structures used in high-performance aircraft, the face sheets are often made of fiber-reinforced composite materials and the core is made of honeycomb. The structures may also have variable thickness so as to satisfy aerodynamic requirements. In the stress analysis, the constant-thickness face sheets are usually considered as membrane and the core is assumed to be inextensible but deformable in the thickness direction. The static behavior of variable-thickness, isotropic and homogeneous sandwich beams was successfully studied by employing a constant-thickness theory but allowing stiffnesses to vary in accordance with local thickness variations. It has been recently found in a refined theory that the analyses based on the constant thickness theory locally can lead to significant errors in structural responses if the sandwich beam is thickness-tapered and the cores are deformable in transverse shear. The errors arise mainly from two factors: (1) the transverse shear components of the membrane forces in the face sheets alter the transverse shears carried by the core; and (2) the face-sheet membrane strains arise from transverse shear deformation of the core. In practice the variable thickness may not only exist in core but also in face sheets. The thickness-variations may even be a type of step function. In this case the transverse shear stress in the face sheets and bending stress in the core should be taken into account in the refined theory mentioned. In the present study, energy principles are employed in deriving governing equations for general bending of anisotropic sandwich beams with variable thickness in both face sheets and cores. Solutions to these equations are based on a finite difference scheme. As an example in application, a simply supported thickness-tapered sandwich beam subject to a concentrated load at its center is considered. Let W' be the maximum deflection of the beam in which face sheets are considered as membrane, while W'' is that based on using the modified refined theory. It is found that W' is always larger than W'', however, the magnitude of (W'- W'') appears to be insensitive to the change of the taper of the beam.

Lu, Chu-Ho↗

A Powerful Toolkit for Synthetic Biology: Over 3.8 Billion Years of Evolution

The combination of evolutionary with engineering principles will enhance synthetic biology. Conversely, synthetic biology has the potential to enrich evolutionary biology by explaining why some adaptive space is empty, on Earth or elsewhere. Synthetic biology, the design and construction of artificial biological systems, substitutes bio-engineering for evolution, which is seen as an obstacle. But because evolution has produced the complexity and diversity of life, it provides a proven toolkit of genetic materials and principles available to synthetic biology. Evolution operates on the population level, with the populations composed of unique individuals that are historical entities. The source of genetic novelty includes mutation, gene regulation, sex, symbiosis, and interspecies gene transfer. At a phenotypic level, variation derives from regulatory control, replication and diversification of components, compartmentalization, sexual selection and speciation, among others. Variation is limited by physical constraints such as diffusion, and chemical constraints such as reaction rates and membrane fluidity. While some of these tools of evolution are currently in use in synthetic biology, all ought to be examined for utility. A hybrid approach of synthetic biology coupled with fine-tuning through evolution is suggested

Rothschild, Lynn J.↗

Acoustic Radiation Pressure

The theoretical foundation of acoustic radiation pressure in plane wave beams is reexamined. It is shown from finite deformation theory and the Boltzmann-Ehrenfest Adiabatic Principle that the Brillouin stress tensor (BST) is the radiation stress in Lagrangian coordinates (not Eulerian coordinates) and that the terms in the BST are not the momentum flux density and mean excess Eulerian stress but are simply contributions to the variation in the wave oscillation period resulting from changes in path length and true wave velocity, respectively, from virtual variations in the strain. It is shown that the radiation stress in Eulerian coordinates is the mean Cauchy stress (not the momentum flux density, as commonly assumed) and that Langevin's second relation does not yield an assessment of the mean Eulerian pressure, since the enthalpy used in the traditional derivations is a function of the thermodynamic tensions - not the Eulerian pressure. It is shown that the transformation between Lagrangian and Eulerian quantities cannot be obtained from the commonly-used expansion of one of the quantities in terms of the particle displacement, since the expansion provides only the difference between the value of the quantity at two different points in Cartesian space separated by the displacement. The proper transformation is obtained only by employing the transformation coefficients of finite deformation theory, which are defined in terms of the displacement gradients. Finite deformation theory leads to the result that for laterally unconfined, plane waves the Lagrangian and Eulerian radiation pressures are equal with the value (1/4)(2K) along the direction of wave propagation, where (K) is the mean kinetic energy density, and zero in directions normal to the propagation direction. This is contrary to the Langevin result that the Lagrangian radiation pressure in the propagation direction is equal to (2K) and the BST result that the Eulerian radiation pressure in that direction is the momentum flux density.

Finite deformation theory↗

Study of methods for direct optical address of integrated optical circuits

Methods for introducing optical information directly, without intervening recording and storage steps, into integrated optical data-processing devices are surveyed. The information is taken to be in the form of a one-dimensional variation of intensity across the beam. Physical phenomena that may be utilized are evaluated, and the most suitable presently known classes of materials for exploitation of each type of interaction are discussed. A variety of possible device configurations are suggested and general principles are outlined whereby many more device types can be generated. A simple experimental device was demonstrated and its operation was analyzed.

Wood, V. E.↗

Computational Fluid Dynamics Modeling of Nickel Hydrogen Batteries

An electrochemical Ni-H2 battery model has been expanded to include thermal effects. A thermal energy conservation equation was derived from first principles. An electrochemical and thermal coupled model was created by the addition of this equation to an existing multiphase, electrochemical model. Charging at various rates was investigated and the results validated against experimental data. Reaction currents, pressure changes, temperature profiles, and concentration variations within the cell are predicted numerically and compared with available data and theory.

Cullion, R.↗

Multiangle Implementation of Atmospheric Correction (MAIAC):: Radiative Transfer Basis and Look-up Tables - 1

This paper describes a radiative transfer basis of the algorithm MAIAC which performs simultaneous retrievals of atmospheric aerosol and bidirectional surface reflectance from the Moderate Resolution Imaging Spectroradiometer (MODIS). The retrievals are based on an accurate semianalytical solution for the top-of-atmosphere reflectance expressed as an explicit function of three parameters of the Ross-Thick Li-Sparse model of surface bidirectional reflectance. This solution depends on certain functions of atmospheric properties and geometry which are precomputed in the look-up table (LUT). This paper further considers correction of the LUT functions for variations of surface pressure/height and of atmospheric water vapor, which is a common task in the operational remote sensing. It introduces a new analytical method for the water vapor correction of the multiple ]scattering path radiance. It also summarizes the few basic principles that provide a high efficiency and accuracy of the LUT ]based radiative transfer for the aerosol/surface retrievals and optimize the size of LUT. For example, the single-scattering path radiance is calculated analytically for a given surface pressure and atmospheric water vapor. The same is true for the direct surface-reflected radiance, which along with the single-scattering path radiance largely defines the angular dependence of measurements. For these calculations, the aerosol phase functions and kernels of the surface bidirectional reflectance model are precalculated at a high angular resolution. The other radiative transfer functions depend rather smoothly on angles because of multiple scattering and can be calculated at coarser angular resolution to reduce the LUT size. At the same time, this resolution should be high enough to use the nearest neighbor geometry angles to avoid costly three ]dimensional interpolation. The pressure correction is implemented via linear interpolation between two LUTs computed for the standard and reduced pressure levels. A linear mixture and a modified linear mixture methods are used to represent different aerosol types in the aerosol/surface retrievals from several base models of the fine and coarse aerosol fractions. In summary, the developed LUT algorithm allows fast high-accuracy simulations of the outgoing radiance with full variability of the atmospheric and surface bidirectional reflectance properties for the aerosol/surface remote sensing.

Lyapustin, Alexei↗

Estimation of Rotary Stability Derivatives at Subsonic and Transonic Speeds

The first part of this paper pertains to the estimation of subsonic rotary stability derivatives of wings. The unsteady potential flow problem is solved by a superposition of steady flow solutions. Numerical results for the damping coefficients of triangular wings are presented as functions of aspect ratio and Mach number, and are compared with experimental results over the Mach number range 0 to 1. In the second part, experimental results are used. to point out a close correlation between the nonlinear variations with angle of attack of the static pitching-moment curve slope and the damping-in-pitch coefficient. The underlying basis for the correlation is found as a result of an analysis in which the indicial function concept and. the principle of super-position are adapted to apply to the nonlinear problem. The form of the result suggests a method of estimating nonlinear damping coefficients from results of static wind-tunnel measurements.

Tobak, Murray↗

Lunar topography - Global determination by radar.

Previous methods used for two-dimensional radar mapping of the moon are contrasted with new techniques that add altitude information to the radar map. Delay-Doppler stereoscopy and delay-Doppler interferometry are shown to provide surface-height variations with higher accuracy and better global fidelity than has been possible previously. Sample results are presented for altitude contours on the moon as obtained with the Haystack and Westford radar systems of the Massachusetts Institute of Technology. An appendix describes the mathematical principles of delay-Doppler interferometry in determining the position of an arbitrary reflecting region of the lunar surface from measurements of the time delay, Doppler shift, and fringe phase of radar echoes from that region.

Shapiro, I. I.↗

The application of NAVSTAR Differential GPS to civil helicopter operations

Principles concerning the operation of the NAVSTAR Global Positioning Systems (GPS) are discussed. Selective availability issues concerning NAVSTAR GPS and differential GPS concepts are analyzed. Civil support and market potential for differential GPS are outlined. It is concluded that differential GPS provides a variation on the baseline GPS system, and gives an assured, uninterrupted level of accuracy for the civilian community.

Beser, J.↗

Controls on Variations of Surface Energy, Water, and Carbon Budgets within Large-Scale Amazon Basin

A key research focus of the LBA Research Program is understanding the space-time variations in interlinked surface energy, water, and carbon budgets, the controls on these variations, and the implications of these controls on the carbon sequestering capacity of the large scale forest-pasture system that dominates the Amaz6nia landscape. Quantification of these variations and controls are investigated by a combination of in situ measurements, remotely sensed measurements from space, and a realistically forced hydrometeorological model coupled to a carbon assimilation model, capable of simulating details within the surface energy and water budgets along with the principle processes of photosynthesis and respiration. Herein we describe the results of an investigation concerning the space-time controls of carbon sources and sinks distributed over the large scale Amazon basin. The results are derived from a carbon-water-energy budget retrieval system for the large scale Amazon basin, which uses a coupled carbon assimilation-hydrometeorological model as an integrating system, forced by both in situ meteorological measurements and remotely sensed radiation and precipitation fluxes obtained from a combination of GOES, SSM/I, TOMS, and TRh4M satellite measurements. Results include validation of (a) retrieved surface radiation and precipitation fluxes based on 30-min averaged surface measurements taken at Ji-Parani in Rondania and Manaus in Amazonas, and (b) modeled sensible, latent, and C02 fluxes based on tower measurements taken at Reserva Jaru, Manaus and Fazenda Nossa Senhora. The space-time controls on carbon sequestration are partitioned into sets of factors classified by: (1) above canopy meteorology, (2) incoming surface radiation, (3) precipitation interception, and (4) indigenous stomatal processes varied over the different land covers of pristine rainforest, partially, and fully logged rainforests, and pasture lands. These are the principle meteorological, thermodynamical, hydrological, and biophysical control paths which perturb net carbon fluxes and sequestration, produce time-space switching of carbon sources and sinks, undergo modulation through atmospheric boundary layer feedbacks, and respond to any discontinuous intervention on the landscape itself such as produced by human intervention in converting rainforest to pasture or conducting selective/clearcut logging operations. The results demonstrate how relative carbon sequestration capacity of the Amazonian ecosystem responds to these controls, and how interpretation of space-time heterogeneities in carbon sequestration depends on a fairly exact quantification of the interacting non-linear properties of photosynthesis in response to incoming solar flux, air-canopy temperatures, and leaf water interception -- and soil respiration in response to upper layer soil temperature and water content. The results also show how the interpretation of the control processes is highly sensitive to the scales at which the surface fluxes are analyzed.

Smith, Eric A.↗

Self-consistent many-electron theory of electron work functions and surface potential characteristics for selected metals

Electron work functions, surface potentials, and electron number density distributions and electric fields in the surface region of 26 metals were calculated from first principles within the free electron model. Calculation proceeded from an expression of the total energy as a functional of the electron number density, including exchange and correlation energies, as well as a first inhomogeneity term. The self-consistent solution was obtained via a variational procedure. Surface barriers were due principally to many-body effects; dipole barriers were small only for some alkali metals, becoming quite large for the transition metals. Surface energies were inadequately described by this model, which neglects atomistic effects. Reasonable results were obtained for electron work functions and surface potential characteristics, maximum electron densities varying by a factor of over 60.

Smith, J. R.↗

Acoustic, Flow Related, and Performance Related Experimental Results for Generation 1.5 High Speed Civil Transport (HSCT) 2-Dimensional Exhaust Nozzles

The principle objectives of the current program were to experimentally investigate the repeatability of acoustic and aerodynamic characteristics of 2D-CD mixer-ejector nozzles and the effects on the acoustic and aerodynamic characteristics of 2D mixer-ejectors due to (1) the configurational variations, which include mixers with aligned CD chutes, aligned convergent chutes, and staggered CD chutes and aerodynamic cycle variables, (2) treatment variations by using different treatment materials, treating the ejector with varying area, location, and treatment thickness for a mixer-ejector configuration, and (3) secondary inlet shape (i.e., a more realistic inlet) and the blockage across the inlet (a possible fin-like structure needed for installation purpose) by modifying one of the inlet of a mixer-ejector configuration. The objectives also included the measurement dynamic pressures internal to the ejector for a few selected configuration to examine the internal noise characteristics.

Salikuddin, M.↗

Ab initio ground states of strongly-correlated materials on quantum computers

The accurate first-principles description of strongly-correlated materials is an important and challenging problem in condensed matter physics. Ab initio downfolding has emerged as a way of deriving accurate many-body Hamiltonians including strong correlations, representing a subspace of interest of a material, using density functional theory calculations as a starting point. However, the solution of these material-specific models can scale exponentially on classical computers, constituting a challenge. Here we propose that utilizing quantum computers for obtaining the properties of downfolded Hamiltonians yields an accurate description of the ground state properties of strongly-correlated systems, while circumventing the exponential scaling problem. We benchmark the solution of Hubbard-like models obtained through downfolding by utilizing a classical tensor network implementation of variational quantum eigensolvers (VQE), and we reveal a strategy for driving the optimization through a hybrid minimization of the energy and maximization of the overlap with an approximate solution obtained through low-cost computational methods. This results in a reduction of the energy error by orders of magnitude compared to conventional VQE approaches, and allows us to reproduce long-range correlations for the first time. We demonstrate our first-principles approach for diverse strongly-correlated materials, correctly predicting the antiferromagnetic state of one-dimensional cuprate Ca 2 CuO 3 , the excitonic ground state of monolayer WTe2, and the charge-ordered state of correlated metal SrVO 3 . Our efficient computational implementation allows us to simulate large systems with up to 54 qubits and encompassing up to four correlated bands, which is indicative of the complexity that our framework can address.

Antonios M Alvertis↗

Silicon solar cell process development, fabrication and analysis

Measurements of minority carrier diffusion lengths were made on the small mesa diodes from HEM Si and SILSO Si. The results were consistent with previous Voc and Isc measurements. Only the medium grain SILSO had a distinct advantage for the non grain boundary diodes. Substantial variations were observed for the HEM ingot 4141C. Also a quantitatively scaled light spot scan was being developed for localized diffusion length measurements in polycrystalline silicon solar cells. A change to a more monochromatic input for the light spot scan results in greater sensitivity and in principle, quantitative measurement of local material qualities is now possible.

Leung, D. C.↗