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At least 487 records · Page 27

SILVERRUSH. XIV. Ly α Luminosity Functions and Angular Correlation Functions from 20,000 Ly α Emitters at z ∼ 2.2–7.3 from up to 24 deg 2 HSC-SSP and CHORUS Surveys: Linking the Postreionization Epoch to the Heart of Reionization

Abstract We present luminosity functions (LFs) and angular correlation functions (ACFs) derived from 18,960 Ly α emitters (LAEs) at z = 2.2−7.3 over a wide survey area of ≲24 deg 2 that are identified in the narrowband data of the HSC-SSP and CHORUS surveys. Confirming the large sample with 241 spectroscopically identified LAEs, we determine Ly α LFs and ACFs in the brighter luminosity range down to 0.5 L ⋆ , and confirm that our measurements are consistent with previous studies but offer significantly reduced statistical uncertainties. The improved precision of our ACFs allows us to clearly detect one-halo terms at some redshifts, and provides large-scale bias measurements that indicate host halo masses of ∼10 11 M ⊙ over z ≃ 2−7. By comparing our Ly α LF (ACF) measurements with reionization models, we estimate the neutral hydrogen fractions in the intergalactic medium to be x H i < 0.05 (= 0.06 − 0.03 + 0.12 ) at z = 5.7 and x H i = 0.1 5 − 0.08 + 0.10 ( 0.21 − 0.14 + 0.19 ), 0.1 8 − 0.12 + 0.14 , and 0.7 5 − 0.13 + 0.09 at z = 6.6, 7.0, and 7.3, respectively. Our findings suggest that the neutral hydrogen fraction remains relatively low, x H i ≲ 0.2, at z = 5−7, but increases sharply at z > 7, reaching x H i ∼ 0.9 by z ≃ 8−9, as indicated by recent JWST studies. The combination of our results from LAE observations with recent JWST observations suggests that the major epoch of reionization occurred at z ∼ 7−8, likely driven by the emergence of massive sources emitting significant ionizing photons.

Umeda, Hiroya (ORCID:0009000801675129)↗

Partial Wave Analysis of Strange Mesons Decaying to K+p+p- in the Reaction ¿p ¿ K+p+p-¿(1520) and the Commissioning of the GlueX DIRC Detector

Hadron spectroscopy is a cornerstone of our understanding of the strong nuclear interactions. Studying the hadron spectrum led to the postulation of quarks and gluons, and the development of Quantum Chromodynamics (QCD), the theory of the strong nuclear force. Today hadron spectroscopy provides an important test of QCD, particularly in the non-perturbative energy regime. One such test is the existence of hybrid hadrons that have gluonic degrees of freedom, e.g. q ?qg states, that are allowed by QCD but have remained elusive in experimental searches. The GlueX experiment located at Thomas Jefferson National Accelerator Facility, is designed to map the light meson spectrum, including hybrid mesons, produced by a linearly polarized photon beam that is scattered off of a liquid hydrogen target. This dissertation concerns the installation and commissioning of the GlueX DIRC upgrade and the analysis of three reactions measured by the GlueX experiment. The GlueX DIRC is a particle identification detector installed as an upgrade to the GlueX experiment in 2019 to improve the experiment?s ability to distinguish pions and kaons. The DIRC uses Cherenkov photons radiated by charged particles that travel faster than the speed of light in the detector medium to determine the velocity of said particles. The velocity measurement is used in conjunction with momentum measurements from other detectors to determine the mass of the particle. The DIRC will be essential to the future of strange meson spectroscopy in GlueX. The reactions ?p ? K+K??+??p, ?p ? K+K??0?0p, ?p ? K+K??0?p were initially chosen for this analysis to search for the hybrid meson candidate ?(2170) and related resonances. The ?(2170) has been observed in e+e? collider experiments decaying to K+K??+?? and K+K??0?0, among other final states. The ?(2170) was not observed in this analysis. The reaction ?p ? K+?+???(1520), a subset of the ?p ? K+K??+??p reaction, was analyzed with a Partial Wave Analysis (PWA) in order to study strange mesons that decay to K+?+??. In the PWA, a useful model for the angular distributions was found but no significant structures could be observed due to statistical limitations.

Hurley, Andrew↗

Atomic Data and Spectral Line Intensities for Ne III

A number of satellites and rockets have been launched to observe radiation from the Sun and other astrophysical objects. Line radiation is emitted when the electron impact excited levels decay to the lower levels by photon emission. From this radiation, the physical parameters such as electron temperature and density of the astrophysical plasma, elemental abundance, and opacity can be inferred. Ne III lines have been observed in H II regions, Ne-rich filaments in supernovae, and planetary nebulae. The allowed line at 489.50 Angstroms due to the transition 2s(sup 2) 2p(sup 5) (sup 3) P2 (goes to) 2s(sup 2)2p(sup 4)(sup 3)P2 has been identified in the solar spectrum by Vernazza and Reeves using Skylab observations. Other Ne III lines in the solar EUV spectrum have been reported by Thomas and Neupert based on observations from the Solar EUV Rocket Telescope and Spectrograph (SERTS) instrument. Atomic data for Ne III have been calculated by using a set of programs developed at, University College, London. The Superstructure and Distorted Wave (DW) programs have been updated over the years. In the Superstructure program, configuration interaction can be taken into account and radial functions are calculated in a modified Thomas-Fermi-Amaldi potential. This is a statistical potential and depends on parameters lambda 1 which are determined by optimizing the weighted sum of term energies. They are found to be lambda(sub 0)=1.2467, lambda(sub 1)=1.1617, and lambda(sub 2)=1.0663. The relativistic corrections are included by using the Breit-Pauli Hamiltonian as a perturbation to the nonrelativistic Hamiltonian. The same potential is used to calculate reactance matrices in the DW approximation in LS coupling. Collision strengths in intermediate coupling are obtained by using term coupling coefficients obtained from the Superstructure program. In this calculation, the configurations used are 2s(sup 2)2p(sup 4), 2s2p(sup 5), 2s(sup 2)2p(sup 3)3s, 2s(sup 2)p(sup 3)3d giving rise to 57 fine-structure levels in intermediate coupling.

Bhatia, A. K.↗

Noise reduction in X-ray photon correlation spectroscopy with convolutional neural networks encoder–decoder models

Abstract Like other experimental techniques, X-ray photon correlation spectroscopy is subject to various kinds of noise. Random and correlated fluctuations and heterogeneities can be present in a two-time correlation function and obscure the information about the intrinsic dynamics of a sample. Simultaneously addressing the disparate origins of noise in the experimental data is challenging. We propose a computational approach for improving the signal-to-noise ratio in two-time correlation functions that is based on convolutional neural network encoder–decoder (CNN-ED) models. Such models extract features from an image via convolutional layers, project them to a low dimensional space and then reconstruct a clean image from this reduced representation via transposed convolutional layers. Not only are ED models a general tool for random noise removal, but their application to low signal-to-noise data can enhance the data’s quantitative usage since they are able to learn the functional form of the signal. We demonstrate that the CNN-ED models trained on real-world experimental data help to effectively extract equilibrium dynamics’ parameters from two-time correlation functions, containing statistical noise and dynamic heterogeneities. Strategies for optimizing the models’ performance and their applicability limits are discussed.

36 MATERIALS SCIENCE↗

Time-Resolved Hanbury Brown–Twiss Interferometry of On-Chip Biphoton Frequency Combs Using Vernier Phase Modulation

Biphoton frequency combs (BFCs) are promising quantum sources for large-scale and high-dimensional quantum information and networking systems. In this context, the spectral purity of individual frequency bins will be critical for realizing quantum networking protocols like teleportation and entanglement swapping. Measurement of the temporal autocorrelation function of the unheralded signal or idler photons comprising the BFC is a key tool for characterizing their spectral purity and in turn verifying the utility of the biphoton state for networking protocols. Yet the experimentally obtainable precision for measuring BFC correlation functions is often severely limited by detector jitter. The fine temporal features in the correlation function—not only of practical value in quantum information, but also of fundamental interest in the study of quantum optics—are lost as a result. We propose a scheme to circumvent this challenge through electro-optic phase modulation, experimentally demonstrating time-resolved Hanbury Brown–Twiss characterization of BFCs generated from an integrated 40.5-GHz Si 3 N 4 microring, up to a 3×3-dimensional two-qutrit Hilbert space. Through slight detuning of the electro-optic drive frequency from the comb’s free spectral range, our approach leverages Vernier principles to magnify temporal features, which would otherwise be averaged out by detector jitter. We demonstrate our approach under both continuous-wave and pulsed-pumping regimes, finding excellent agreement with theory. In conclusion, our method reveals not only the collective statistics of the contributing frequency bins but also their temporal shapes—features lost in standard fully integrated autocorrelation measurements.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗

EGRET observations of the Vela pulsar, PSR0833-45

During the all sky survey (May 1991 to November 1992) of the Compton Gamma Ray Observatory, the Vela pulsar PSR0833-45 was in the field of view of the Energetic Gamma Ray Experiment Telescope (EGRET) in ten separate viewing periods. The pulsar was detected in each one. The average intensity from 100 MeV to 2GeV was (7.8 +/- 1.0) x 10(exp -6) photons /sq cm/s, which indicates that the pulsar in the years 1991/92 was in a state comparable to the low fluxes observed in 1977-1980. No significant changes in intensity were detected during the EGRET observations. The total spectrum of PSR0833-45 measured by EGRET can be described by a power-law with index -1.70 +/- 0.02 over the range 30 MeV to 2 GeV. The extrapolation of this spectrum into the 3-30 MeV range agrees with the observations by COMPTEL. Above 2-4 GeV EGRET detects a strong spectral break. The lightcurves obtained show a familiar structure in the phase histogram: two peaks separated by 0.424 +/- 0.002 in phase with considerable emission in the phase interval between the peaks. The first gamma ray peak maximum trails the single radio peak maximum by 10.54 +/- 0.09 ms (= 0.118 +/- 0.001 in phase). The widths of the emission peaks (FWHM) are 2.7 ms for the first peak (0.03 phase) and 4.1 ms for the second peak (0.05 phase). The widths are approximately constant below a GeV, but show a tendency to become narrower at higher energies. The statistics available for the Vela observations allow for a division of the lightcurve into eight phase intervals. The emission peak cores (central FWHM) with leading and trailing wings and two interval regions were defined and spectra were derived for all parts of the lightcurve. The energy spectra for the eight phase intervals show significant differences: the first peak (approximately E(exp -1.81 +/- 0.04)) is somewhat softer than the second peak (approximately E(exp -1.71 +/- 0.03)); the wings attached to each peak show softer spectra than the core of the peaks; the interval emission has the hardest spectrum (approximately E(exp -1.52 +/- 0.03)).

Kanbach, G.↗

Determination of X-ray detection limit and applications in perovskite X-ray detectors

X-ray detection limit and sensitivity are important figure of merits for perovskite X-ray detectors, but literatures lack a valid mathematic expression for determining the lower limit of detection for a perovskite X-ray detector. In this work, we present a thorough analysis and new method for X-ray detection limit determination based on a statistical model that correlates the dark current and the X-ray induced photocurrent with the detection limit. The detection limit can be calculated through the measurement of dark current and sensitivity with an easy-to-follow practice. Alternatively, the detection limit may also be obtained by the measurement of dark current and photocurrent when repeatedly lowering the X-ray dose rate. While the material quality is critical, we show that the device architecture and working mode also have a significant influence on the sensitivity and the detection limit. Our work establishes a fair comparison metrics for material and detector development.

47 OTHER INSTRUMENTATION↗

Forecasting constraints on the mean free path of ionizing photons at z ≥ 5.4 from the Lyman-α forest flux autocorrelation function

ABSTRACT Fluctuations in Lyman-α (Ly α) forest transmission towards high-z quasars are partially sourced from spatial fluctuations in the ultraviolet background, the level of which are set by the mean free path of ionizing photons (λmfp). The autocorrelation function of Ly α forest flux characterizes the strength and scale of transmission fluctuations and, as we show, is thus sensitive to λmfp. Recent measurements at z ∼ 6 suggest a rapid evolution of λmfp at z > 5.0 which would leave a signature in the evolution of the autocorrelation function. For this forecast, we model mock Ly α forest data with properties similar to the XQR-30 extended data set at 5.4 ≤ z ≤ 6.0. At each z, we investigate 100 mock data sets and an ideal case where mock data matches model values of the autocorrelation function. For ideal data with λmfp = 9.0 cMpc at z = 6.0, we recover $\lambda _{\text{mfp}}=12^{+6}_{-3}$ cMpc. This precision is comparable to direct measurements of λmfp from the stacking of quasar spectra beyond the Lyman limit. Hypothetical high-resolution data leads to a $\sim 40~{{\ \rm per\ cent}}$ reduction in the error bars over all z. The distribution of mock values of the autocorrelation function in this work is highly non-Gaussian for high-z, which should caution work with other statistics of the high-z Ly α forest against making this assumption. We use a rigorous statistical method to pass an inference test, however future work on non-Gaussian methods will enable higher precision measurements.

Astronomy & Astrophysics↗

Coherent Mode Decomposition for Kolmogorov Optical Turbulence in a Finite Aperture

An analysis of the coherent mode decomposition of an optical field after propagation through atmospheric turbulence is presented. The coherent modes represent an ideal basis by which to decompose the field for design of mode-limited optical systems. Due to rotational symmetry of the Fredholm integral operator for Kolmogorov optical turbulence, the coherent modes exhibit separable solutions classified by a radial and azimuthal mode index. The study of the coherent modes is then reduced to that of the radial functions determined by the coherence ratio and obscuration ratio. Analysis of the spectrum of eigenvalues yields sharp bounds on the efficiency of receivers using incoherent or coherent combining with mode-limited photonic devices in the presence of Kolmogorov turbulence. The effective number of modes needed to represent Kolmogorov optical turbulence is studied via the von Neumann entropy, purity, and largest eigenvalue, and the differences in the different definitions is discussed. The similarity of the coherent modes to linearly polarized (LP) fiber modes is quantified yielding a precise characterization of the maximum gain that can be achieved in mode-limited systems via mode shaping techniques. As a final application, a mode sorting technique is presented for optimally splitting power from atmospherically degraded light into a finite number of modes simultaneously maximizing total coupling efficiency and minimizing the difference in average power between channels.

free-space optical communication↗

Weak Hard X-Ray Emission from Two Broad Absorption Line Quasars Observed with NuStar: Compton-Thick Absorption or Intrinsic X-Ray Weakness?

We present Nuclear Spectroscopic Telescope Array (NuSTAR) hard X-ray observations of two X-ray weak broad absorption line (BAL) quasars, PG 1004+130 (radio loud) and PG 1700+518 (radio quiet). Many BAL quasars appear X-ray weak, probably due to absorption by the shielding gas between the nucleus and the accretion-disk wind. The two targets are among the optically brightest BAL quasars, yet they are known to be significantly X-ray weak at rest-frame 2-10 keV (16-120 times fainter than typical quasars). We would expect to obtain approx. or equal to 400-600 hard X-ray (is greater than or equal to 10 keV) photons with NuSTAR, provided that these photons are not significantly absorbed N(sub H) is less than or equal to 10(exp24) cm(exp-2). However, both BAL quasars are only detected in the softer NuSTAR bands (e.g., 4-20 keV) but not in its harder bands (e.g., 20-30 keV), suggesting that either the shielding gas is highly Compton-thick or the two targets are intrinsically X-ray weak. We constrain the column densities for both to be N(sub H) 7 × 10(exp 24) cm(exp-2) if the weak hard X-ray emission is caused by obscuration from the shielding gas. We discuss a few possibilities for how PG 1004+130 could have Compton-thick shielding gas without strong Fe Kα line emission; dilution from jet-linked X-ray emission is one likely explanation. We also discuss the intrinsic X-ray weakness scenario based on a coronal-quenching model relevant to the shielding gas and disk wind of BAL quasars. Motivated by our NuSTAR results, we perform a Chandra stacking analysis with the Large Bright Quasar Survey BAL quasar sample and place statistical constraints upon the fraction of intrinsically X-ray weak BAL quasars; this fraction is likely 17%-40%.

nuclei↗

Coherent Mode Decomposition for Kolmogorov Optical Turbulence in a Finite Aperture

An analysis of the coherent mode decomposition of an optical field after propagation through atmospheric turbulence is presented. The coherent modes represent an ideal basis by which to decompose the field for design of mode-limited optical systems. Using the rotational symmetry of the Fredholm integral operator for Kolmogorov optical turbulence, it is shown that the coherent modes exhibit separable solutions classified by radial and azimuthal quantum numbers. The study of the coherent modes is then reduced that of the radial functions determined by the aperture-coherence diameter ratio and obscuration ratio. Analysis of the spectrum of eigenvalues yields sharp bounds on the efficiency of receivers using incoherent or coherent combining with mode-limited photonic devices in the presence of Kolmogorov turbulence. The effective number of modes needed to represent Kolmogorov optical turbulence is studied via the von Neumann entropy, purity, and largest eigenvalue, and the differences in the different definitions is discussed. The similarity of the coherent modes to linearly polarized (LP) fiber modes is quantified yielding a precise characterization of the maximum gain that can be achieved in mode-limited systems via mode shaping techniques. As a final application, a mode sorting technique is presented for optimally splitting power from atmospherically degraded light into a finite number of modes simultaneously maximizing total coupling efficiency and minimizing the average and instantaneous power ratio between channels.

free-space optical communication↗

Direct electron-pair production by high energy heavy charged particles

Direct electron pain production via virtual photons by moving charged particles is a unique electro-magnetic process having a substantial dependence on energy. Most electro-magnetic processes, including transition radiation, cease to be sensitive to the incident energy above 10 TeV/AMU. Thus, it is expected, that upon establishment of cross section and detection efficiency of this process, it may provide a new energy measuring technique above 10 TeV/AMU. Three accelerator exposures of emulsion chambers designed for measurements of direct electron-pains were performed. The objectives of the investigation were to provide the fundamental cross-section data in emulsion stacks to find the best-fit theoretical model, and to provide a calibration of measurements of direct electron-pairs in emulsion chamber configurations. This paper reports the design of the emulsion chambers, accelerator experiments, microscope measurements, and related considerations for future improvements of the measurements, and for possible applications to high energy cosmic ray experiments. Also discussed are the results from scanning 56m of emulsion tracks at 1200x magnification so that scanning efficiency is optimized. Measurements of the delta-ray range spectrum were also performed for much shorter track lengths, but with sufficiently large statistics in the number of measured delta-rays.

Takahashi, Y.↗

Direct Detection Doppler Lidar for Spaceborne Wind Measurement

Aerosol and molecular based versions of the double-edge technique can be used for direct detection Doppler lidar spaceborne wind measurement. The edge technique utilizes the edge of a high spectral resolution filter for high accuracy wind measurement using direct detection lidar. The signal is split between an edge filter channel and a broadband energy monitor channel. The energy monitor channel is used for signal normalization. The edge measurement is made as a differential frequency measurement between the outgoing laser signal and the atmospheric backscattered return for each pulse. As a result the measurement is insensitive to laser and edge filter frequency jitter and drift at a level less than a few parts in 10(exp 10). We have developed double edge versions of the edge technique for aerosol and molecular-based lidar measurement of the wind. Aerosol-based wind measurements have been made at Goddard Space Flight Center and molecular-based wind measurements at the University of Geneva. We have demonstrated atmospheric measurements using these techniques for altitudes from 1 to more than 10 km. Measurement accuracies of better than 1.25 m/s have been obtained with integration times from 5 to 30 seconds. The measurements can be scaled to space and agree, within a factor of two, with satellite-based simulations of performance based on Poisson statistics. The theory of the double edge aerosol technique is described by a generalized formulation which substantially extends the capabilities of the edge technique. It uses two edges with opposite slopes located about the laser frequency at approximately the half-width of each edge filter. This doubles the signal change for a given Doppler shift and yields a factor of 1.6 improvement in the measurement accuracy compared to the single edge technique. The use of two high resolution edge filters substantially reduces the effects of Rayleigh scattering on the measurement, as much as order of magnitude, and allows the signal to noise ratio to be substantially improved in areas of low aerosol backscatter. We describe a method that allows the Rayleigh and aerosol components of the signal to be independently determined using the two edge channels and an energy monitor channel. The effects of Rayleigh scattering may then subtracted from the measurement and we show that the correction process does not significantly increase the measurement noise for Rayleigh to aerosol ratios up to 10. We show that for small Doppler shifts a measurement accuracy of 0.4 m/s can be obtained for 5000 detected photon, 1.2 m/s for 1000 detected photons, and 3.7 m/s for 50 detected photons for a Rayleigh to aerosol ratio of 5. Methods for increasing the dynamic range of the aerosol-based system to more than +/- 100 m/s are given.

Korb, C. Laurence↗

Search for $\mu^- \rightarrow e^+$ conversion: what can be learned from the SINDRUM-II positron data on a gold target

In their 2006 paper setting the current limit on \mumemconv\ conversion search on a gold target \cite{sindrum_ii:Bertl2006}, the SINDRUM-II collaboration published, along with the electron momentum distribution, the momentum distribution of reconstructed positrons. Near the positron spectrum endpoint, there is a statistically significant excess of observed events over the expected background. We estimate that in the region 88 MeV/c < p < 95 MeV/c there are 13 events with an expected background of about 1-1.5 event, which has not been discussed by the authors. Those 13 events form a bump with a width consistent with the experimental resolution, making one think of a $\mu^- \rightarrow e^+$ conversion signal. However, the reconstructed position of the bump is about 1 MeV/c, or $\sim\ 4\sigma_p$, lower than the expected $\mu^- Au \rightarrow e^+ Ir $ signal, which strongly discourages the exotic interpretation. The excess, however, could be due to an exclusive dipole radiative muon capture (RMC) transition $^{197}Au(GS) ~\rightarrow~ ^{197}Pt(GS)$ with the branching fraction of about $2\cdot 10^{-4}$. Such a transition would not be resolved by the existing RMC measurements. We conclude that the exclusive RMC transitions could significantly modify the positron spectrum near the kinematic endpoint, to fully exploit the physics potential of the upcoming experiments such as Mu2e and COMET, a better theoretical understanding of the RMC spectrum on nuclei is needed. A high-resolution measurement of the RMC photon spectra has to be carried out. Without that, the sensitivity of the searches for $\mu^- \rightarrow e^+$ and $\mu^- \rightarrow e^-$ might be severely limited by unknown probabilities of RMC transitions to the exclusive low-lying states of the daughter nuclei.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

Approximate Bayesian Computation applied to the Diffuse Gamma-Ray Sky

ABSTRACT Many sources contribute to the diffuse gamma-ray background (DGRB), including star forming galaxies, active galactic nuclei, and cosmic ray interactions in the Milky Way. Exotic sources, such as dark matter annihilation, may also make some contribution. The photon counts-in-pixels distribution is a powerful tool for analysing the DGRB and determining the relative contributions of different sources. However, including photon energy information in a likelihood analysis of the counts-in-pixels distribution quickly becomes computationally intractable as the number of source types and energy bins increase. Here, we apply the likelihood-free method of approximate Bayesian computation (ABC) to the problem. We consider a mock analysis that includes contributions from dark matter annihilation in Galactic subhaloes as well as astrophysical backgrounds. We show that our results using ABC are consistent with the exact likelihood when energy information is discarded, and that significantly tighter parameter constraints can be obtained with ABC when energy information is included. ABC presents a powerful tool for analysing the DGRB and understanding its varied origins.

79 ASTRONOMY AND ASTROPHYSICS↗

Disordered hyperuniform solid state materials

Disordered hyperuniform (DHU) states are recently discovered exotic states of condensed matter. DHU systems are similar to liquids or glasses in that they are statistically isotropic and lack conventional long-range translational and orientational order. On the other hand, they completely suppress normalized infinite-wavelength density fluctuations like crystals and, in this sense, possess a hidden long-range correlation. Very recently, there have been several exciting discoveries of disordered hyperuniformity in solid-state materials, including amorphous carbon nanotubes, amorphous 2D silica, amorphous graphene, defected transition metal dichalcogenides, defected pentagonal 2D materials, and medium/high-entropy alloys. It has been found that the DHU states of these materials often possess a significantly lower energy than other disorder models and can lead to unique electronic and thermal transport properties, which results from mechanisms distinct from those identified for their crystalline counterparts. For example, DHU states can enhance electronic transport in 2D amorphous silica; DHU medium/high-entropy alloys realize the Vegard's law and possess enhanced electronic bandgaps and thermal transport at low temperatures. These unique properties open up many promising potential device applications in optoelectronics and thermoelectrics. Here, we provide a focused review on these important new developments of hyperuniformity in solid-state materials, taking an applied and “materials” perspective, which complements the existing reviews on hyperuniformity in physical systems and photonic materials. As a result, future directions and outlook are also provided, with a focus on the design and discovery of DHU quantum materials for quantum information science and engineering.

2D materials↗

Application of FISH based G2-PCC assay for the cytogenetic assessment of high radiation dose exposures: Potential implications for rapid triage biodosimetry

The main goal of this study is to test the utility of calyculin A induced G2-PCC assay as a biodosimetry triage tool for assessing a wide range of low and acute high radiation dose exposures of photons. Towards this initiative, chromosome aberrations induced by low and high doses of x-rays were evaluated and characterized in G2-prematurely condensed chromosomes (G2-PCCs) by fluorescence in situ hybridization (FISH) using human centromere and telomere specific PNA (peptide nucleic acid) probes. A dose dependent increase in the frequency of dicentric chromosomes was observed in the G2-PCCs up to 20 Gy of x-rays. The combined yields of dicentrics and rings in the G2-PCCs showed a clear dose dependency up to 20 Gy from 0.02/cell for 0.1 Gy to 14.98/cell for 20 Gy. Centric rings were observed more frequently than acentric ring chromosomes in the G2-PCCs at all the radiation doses from 1 Gy to 20 Gy. A head-to-head comparison was also performed by FISH on the yields of chromosome aberrations induced by different doses of x-rays (0 Gy -7.5 Gy) in colcemid arrested metaphase chromosomes and calyculin A induced G2-PCCs. In general, the frequencies of dicentrics, rings and acentric fragments were slightly higher in G2-PCCs than in colcemid arrested metaphase chromosomes at all the radiation doses, but the differences were not statistically significant. To reduce the turnaround time for absorbed radiation dose estimation, attempt was made to obtain G2-PCCs by reducing the culture time to 36 hrs. The absorbed doses estimated in x-rays irradiated (0,1,2 and 4 Gy) G2-PCCs after 36 hrs of culture were grossly like that of G2-PCCs and colcemid arrested metaphase chromosomes prepared after 48 hrs of culture. Our study indicates that the shortened version of calyculin A induced G2-PCC assay coupled with the FISH staining technique can serve as an effective triage biodosimetry tool for large-scale radiological/nuclear incidents.

Science & Technology - Other Topics↗

Two-sample discrimination of Poisson means

This paper presents a statistical test for detecting significant differences between two random count accumulations. The null hypothesis is that the two samples share a common random arrival process with a mean count proportional to each sample's exposure. The model represents the partition of N total events into two counts, A and B, as a sequence of N independent Bernoulli trials whose partition fraction, f, is determined by the ratio of the exposures of A and B. The detection of a significant difference is claimed when the background (null) hypothesis is rejected, which occurs when the observed sample falls in a critical region of (A, B) space. The critical region depends on f and the desired significance level, alpha. The model correctly takes into account the fluctuations in both the signals and the background data, including the important case of small numbers of counts in the signal, the background, or both. The significance can be exactly determined from the cumulative binomial distribution, which in turn can be inverted to determine the critical A(B) or B(A) contour. This paper gives efficient implementations of these tests, based on lookup tables. Applications include the detection of clustering of astronomical objects, the detection of faint emission or absorption lines in photon-limited spectroscopy, the detection of faint emitters or absorbers in photon-limited imaging, and dosimetry.

Lampton, M.↗