Engineering Papers⌕ Search

SEARCH · Engineering Papers

Results for “model weights”

Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 469 records · Page 26

Measurement of Low Amounts of Precipitable Water Vapor Using Ground-Based Millimeterwave Radiometry

Extremely dry conditions characterized by amounts of precipitable water vapor (PWV) as as 1-2 mm commonly occur in high-latitude regions during the winter months. While such atmospheres carry only a few percent of the latent heat energy compared to tropical atmospheres, the effects of low vapor amounts on the polar radiation budget - both directly through modulation of longwave radiation and indirectly through the formation of clouds - are considerable. Accurate measurements of precipitable water vapor (PWV) during such dry conditions are needed to improve polar radiation models for use in understanding and predicting change in the climatically sensitive polar regions. To this end, the strong water vapor absorption at 183.310 GHz provides a unique means of measuring low amounts of PWV. Weighting function analysis, forward model calculations based upon a 7-year radiosonde dataset, and retrieval simulations consistently predict that radiometric measurements made using several millimeter-wavelength (MMW) channels near the 183 GHz line, together with established microwave (MW) measurements at the 22.235 GHz water vapor line and -3 1 GHz atmospheric absorption window can be used to determine within 5% uncertainty the full range of PWV expected in the Arctic. This unique collective capability stands in spite of accuracy limitations stemming from uncertainties due to the sensitivity of the vertical distribution of temperature and water vapor at MMW channels. In this study the potential of MMW radiometry using the 183 GHz line for measuring low amounts of PWV is demonstrated both theoretically and experimentally. The study uses data obtained during March 1999 as part of an experiment conducted at the Department of Energy s Cloud and Radiation Testbed (CART) near Barrow, Alaska. Several radiometers from both NOAA and NASA were deployed during the experiment to provide the first combined MMW and MW ground-based data set during dry arctic conditions. Single-channel retrievals of PWV were performed using the MW and MMW data. Discrepancies in the retrieved values were found to be consistent with differences observed between measured brightness temperatures (TBs) and forward-modeled TBs based on concurrent radiosonde profiles. These discrepancies are greater than can be explained by measurement error alone and are attributed to absorption model uncertainty. We discuss here the measurements, retrieval technique, and line model discrepancies along with difficulties and potential of MMW/MW PWV measurement.

Racette, Paul E.↗

Exercise Prevents Weight Gain and Alters the Gut Microbiota in a Mouse Model of High Fat Diet-Induced Obesity

Diet-induced obesity (DIO) is a significant health concern which has been linked to structural and functional changes in the gut microbiota. Exercise (Ex) is effective in preventing obesity, but whether Ex alters the gut microbiota during development with high fat (HF) feeding is unknown. Determine the effects of voluntary Ex on the gastrointestinal microbiota in LF-fed mice and in HF-DIO. Male C57BL/6 littermates (5 weeks) were distributed equally into 4 groups: low fat (LF) sedentary (Sed) LF/Sed, LF/ Ex, HF/Sed and HF/Ex. Mice were individually housed and LF/Ex and HF/Ex cages were equipped with a wheel and odometer to record Ex. Fecal samples were collected at baseline, 6 weeks and 12 weeks and used for bacterial DNA isolation. DNA was subjected both to quantitative PCR using primers specific to the 16S rRNA encoding genes for Bacteroidetes and Firmicutes and to sequencing for lower taxonomic identification using the Illumina MiSeq platform. Data were analyzed using a one or two-way ANOVA or Pearson correlation. HF diet resulted in significantly greater body weight and adiposity as well as decreased glucose tolerance that were prevented by voluntary Ex (p<0.05). Visualization of Unifrac distance data with principal coordinates analysis indicated clustering by both diet and Ex at week 12. Sequencing demonstrated Ex-induced changes in the percentage of major bacterial phyla at 12 weeks. A correlation between total Ex distance and the ΔCt Bacteroidetes: ΔCt Firmicutes ratio from qPCR demonstrated a significant inverse correlation (r 2 = 0.35, p = 0.043). Conclusion: Ex induces a unique shift in the gut microbiota that is different from dietary effects. Microbiota changes may play a role in Ex prevention of HF-DIO.

59 BASIC BIOLOGICAL SCIENCES↗

Comparative performance of double-focus and quadrupole mass spectrometers

Light-weight flight type double focus and quadruple mass spectrometer models were compared. Data cover size, weight, and power sensitivity required to achieve same resolution sensitivity at given mass number. Comparison was made using mathematical relationships. Analysis was confined to equal ion source area sensitivity variations not more than 40% over mass range.

Wilson, S. K.↗

Test-Anchored Vibration Response Predictions for an Acoustically Energized Curved Orthogrid Panel with Mounted Components

rich body of vibroacoustic test data was recently generated at Marshall Space Flight Center for component-loaded curved orthogrid panels typical of launch vehicle skin structures. The test data were used to anchor computational predictions of a variety of spatially distributed responses including acceleration, strain and component interface force. Transfer functions relating the responses to the input pressure field were generated from finite element based modal solutions and test-derived damping estimates. A diffuse acoustic field model was applied to correlate the measured input sound pressures across the energized panel. This application quantifies the ability to quickly and accurately predict a variety of responses to acoustically energized skin panels with mounted components. Favorable comparisons between the measured and predicted responses were established. The validated models were used to examine vibration response sensitivities to relevant modeling parameters such as pressure patch density, mesh density, weight of the mounted component and model form. Convergence metrics include spectral densities and cumulative root-mean squared (RMS) functions for acceleration, velocity, displacement, strain and interface force. Minimum frequencies for response convergence were established as well as recommendations for modeling techniques, particularly in the early stages of a component design when accurate structural vibration requirements are needed relatively quickly. The results were compared with long-established guidelines for modeling accuracy of component-loaded panels. A theoretical basis for the Response/Pressure Transfer Function (RPTF) approach provides insight into trends observed in the response predictions and confirmed in the test data. The software developed for the RPTF method allows easy replacement of the diffuse acoustic field with other pressure fields such as a turbulent boundary layer (TBL) model suitable for vehicle ascent. Structural responses using a TBL model were demonstrated, and wind tunnel tests have been proposed to anchor the predictions and provide new insight into modeling approaches for this environment. Finally, design load factors were developed from the measured and predicted responses and compared with those derived from traditional techniques such as historical Mass Acceleration Curves and Barrett scaling methods for acreage and component-loaded panels.

Frady, Gregory P.↗

Finite Element Based HWB Centerbody Structural Optimization and Weight Prediction

This paper describes a scalable structural model suitable for Hybrid Wing Body (HWB) centerbody analysis and optimization. The geometry of the centerbody and primary wing structure is based on a Vehicle Sketch Pad (VSP) surface model of the aircraft and a FLOPS compatible parameterization of the centerbody. Structural analysis, optimization, and weight calculation are based on a Nastran finite element model of the primary HWB structural components, featuring centerbody, mid section, and outboard wing. Different centerbody designs like single bay or multi-bay options are analyzed and weight calculations are compared to current FLOPS results. For proper structural sizing and weight estimation, internal pressure and maneuver flight loads are applied. Results are presented for aerodynamic loads, deformations, and centerbody weight.

Gern, Frank H.↗

Data-Driven Robust RVFLNs Modeling of a Blast Furnace Iron-Making Process Using Cauchy Distribution Weighted M-Estimation

Optimal operation of a practical blast furnace (BF) ironmaking process depends largely on a good measurement of molten iron quality (MIQ) indices. However, measuring the MIQ online is not feasible using the available techniques. In this paper, a novel data-driven robust modeling is proposed for online estimation of MIQ using improved random vector functional-link networks (RVFLNs). Since the output weights of traditional RVFLNs are obtained by the least squares approach, a robustness problem may occur when the training dataset is contaminated with outliers. This affects the modeling accuracy of RVFLNs. To solve this problem, a Cauchy distribution weighted M-estimation based robust RFVLNs is proposed. Since the weights of different outlier data are properly determined by the Cauchy distribution, their corresponding contribution on modeling can be properly distinguished. Thus robust and better modeling results can be achieved. Moreover, given that the BF is a complex nonlinear system with numerous coupling variables, the data-driven canonical correlation analysis is employed to identify the most influential components from multitudinous factors that affect the MIQ indices to reduce the model dimension. Finally, experiments using industrial data and comparative studies have demonstrated that the obtained model produces a better modeling and estimating accuracy and stronger robustness than other modeling methods.

42 ENGINEERING↗

Adult weight change and premenopausal breast cancer risk: A prospective pooled analysis of data from 628,463 women

Early-adulthood body size is strongly inversely associated with risk of premenopausal breast cancer. It is unclear whether subsequent changes in weight affect risk. We pooled individual-level data from 17 prospective studies to investigate the association of weight change with premenopausal breast cancer risk, considering strata of initial weight, timing of weight change, other breast cancer risk factors and breast cancer subtype. Hazard ratios (HR) and 95% confidence intervals (CI) were obtained using Cox regression. Among 628,463 women, 10,886 were diagnosed with breast cancer before menopause. Models adjusted for initial weight at ages 18–24 years and other breast cancer risk factors showed that weight gain from ages 18–24 to 35–44 or to 45–54 years was inversely associated with breast cancer overall (e.g., HR per 5 kg to ages 45–54: 0.96, 95% CI: 0.95–0.98) and with oestrogen-receptor(ER)-positive breast cancer (HR per 5 kg to ages 45–54: 0.96, 95% CI: 0.94–0.98). Weight gain from ages 25–34 was inversely associated with ER-positive breast cancer only and weight gain from ages 35–44 was not associated with risk. None of these weight gains were associated with ER-negative breast cancer. Weight loss was not consistently associated with overall or ER-specific risk after adjusting for initial weight. Weight increase from early-adulthood to ages 45–54 years is associated with a reduced premenopausal breast cancer risk independently of early-adulthood weight. Biological explanations are needed to account for these two separate factors.

60 APPLIED LIFE SCIENCES↗

Q-factor of (In,Ga)N containing III-nitride microcavity grown by multiple deposition techniques

A 3λ/2 (In,Ga)N/GaN resonant cavity, designed for ∼415 nm operation, is grown by molecular beam epitaxy and is sandwiched between a 39.5-period (In,Al)N/GaN distributed Bragg reflector (DBR), grown on c-plane GaN-on-sapphire pseudo-substrate by metal-organic vapor phase epitaxy and an 8-period SiO{sub 2}/ZrO{sub 2} DBR, deposited by electron beam evaporation. Optical characterization reveals an improvement in the cavity emission spectral purity of approximately one order of magnitude due to resonance effects. The combination of spectrophotometric and micro-reflectivity measurements confirms the strong quality (Q)-factor dependence on the excitation spot size. We derive simple analytical formulas to estimate leak and residual absorption losses and propose a simple approach to model the Q-factor and to give a quantitative estimation of the weight of cavity disorder. The model is in good agreement with both transfer-matrix simulation and the experimental findings. We point out that the realization of high Q-factor (In,Ga)N containing microcavities on GaN pseudo-substrates is likely to be limited by the cavity disorder.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗

On-Board Propulsion System Analysis of High Density Propellants

The impact of the performance and density of on-board propellants on science payload mass of Discovery Program class missions is evaluated. A propulsion system dry mass model, anchored on flight-weight system data from the Near Earth Asteroid Rendezvous mission is used. This model is used to evaluate the performance of liquid oxygen, hydrogen peroxide, hydroxylammonium nitrate, and oxygen difluoride oxidizers with hydrocarbon and metal hydride fuels. Results for the propellants evaluated indicate that the state-of-art, Earth Storable propellants with high performance rhenium engine technology in both the axial and attitude control systems has performance capabilities that can only be exceeded by liquid oxygen/hydrazine, liquid oxygen/diborane and oxygen difluoride/diborane propellant combinations. Potentially lower ground operations costs is the incentive for working with nontoxic propellant combinations.

Schneider, Steven J.↗

Variational four-dimensional analysis using quasi-geostrophic constraints

A variational four-dimensional analysis technique using quasi-geostrophic models as constraints is examined using gridded fields as data. The analysis method uses a standard iterative nonlinear minimization technique to find the solution to the constraining forecast model which best fits the data as measured by a predefined functional. The minimization algorithm uses the derivative of the functional with respect to each of the initial condition values. This derivative vector is found by inserting the weighted differences between the model solution and the inserted data into a backwards integrating adjoint model. The four-dimensional analysis system was examined by applying it to fields created from a primitive equations model forecast and to fields created from satellite retrievals. The results show that the technique has several interesting characteristics not found in more traditional four-dimensional assimilation techniques. These features include a close fit of the model solution to the observations throughout the analysis interval and an insensitivity to the frequency of data insertion or the amount of data. The four-dimensional analysis technique is very versatile and can be extended to more complex problems with little theoretical difficulty.

Derber, John C.↗

Time Course and Accumulated Risk of Severe Urinary Adverse Events After High- Versus Low-Dose-Rate Prostate Brachytherapy With or Without External Beam Radiation Therapy

Purpose: Severe urinary adverse events (UAEs) include surgical treatment of urethral stricture, urinary incontinence, and radiation cystitis. We compared the incidence of grade 3 UAEs, according to the Common Terminology Criteria for Adverse Events, after low-dose-rate (LDR) and high-dose-rate (HDR) brachytherapy, as well as after LDR plus external beam radiation therapy (EBRT) and HDR plus EBRT. Methods and Materials: Men aged >65 years with nonmetastatic prostate cancer were identified from the Surveillance, Epidemiology, and End Results–Medicare database who were treated with LDR (n=12,801), HDR (n=685), LDR plus EBRT (n=8518), or HDR plus EBRT (n=2392). The populations were balanced by propensity weighting, and the Kaplan-Meier incidence of severe UAEs was compared. Propensity-weighted Cox proportional hazards models were used to compare the adjusted hazard of UAEs. These UAEs were compared with those in a cohort of men not treated for prostate cancer. Results: Median follow-up was 4.3 years. At 8 years, the propensity-weighted cumulative UAE incidence was highest after HDR plus EBRT (26.6% [95% confidence interval, 23.8%-29.7%]) and lowest after LDR (15.7% [95% confidence interval, 14.8%-16.6%]). The absolute excess risk over nontreated controls at 8 years was 1.9%, 3.8%, 8.4%, and 12.9% for LDR, HDR, LDR plus EBRT, and HDR plus EBRT, respectively. These represent numbers needed to harm of 53, 26, 12, and 8 persons, respectively. The additional risk of development of a UAE related to treatment for LDR, LDR plus EBRT, and HDR plus EBRT was greatest within the 2 years after treatment and then continued to decline over time. Beyond 4 years, the risk of development of a new severe UAE matched the baseline risk of the control population for all treatments. Conclusions: Toxicity differences were observed between LDR and HDR, but the differences did not meet statistical significance. However, combination radiation therapy (either HDR plus EBRT or LDR plus EBRT) increases the risk of severe UAEs compared with HDR alone or LDR alone. The highest increased risk of urinary toxicity occurs within the 2 years after therapy and then declines to an approximately 1% increase in incidence per year.

62 RADIOLOGY AND NUCLEAR MEDICINE↗

A Spreadsheet Simulation Tool for Terrestrial and Planetary Balloon Design

During the early stages of new balloon design and development, it is necessary to conduct many trade studies. These trade studies are required to determine the design space, and aid significantly in determining overall feasibility. Numerous point designs then need to be generated as details of payloads, materials, mission, and manufacturing are determined. To accomplish these numerous designs, transient models are both unnecessary and time intensive. A steady state model that uses appropriate design inputs to generate system-level descriptive parameters can be very flexible and fast. Just such a steady state model has been developed and has been used during both the MABS 2001 Mars balloon study and the Ultra Long Duration Balloon Project. Using Microsoft Excel's built-in iteration routine, a model was built. Separate sheets were used for performance, structural design, materials, and thermal analysis as well as input and output sheets. As can be seen from figure 1, the model takes basic performance requirements, weight estimates, design parameters, and environmental conditions and generates a system level balloon design. Figure 2 shows a sample output of the model. By changing the inputs and a few of the equations in the model, balloons on earth or other planets can be modeled. There are currently several variations of the model for terrestrial and Mars balloons, as well there are versions of the model that perform crude material design based on strength and weight requirements. To perform trade studies, the Visual Basic language built into Excel was used to create an automated matrix of designs. This trade study module allows a three dimensional trade surface to be generated by using a series of values for any two design variables. Once the fixed and variable inputs are defined, the model automatically steps through the input matrix and fills a spreadsheet with the resulting point designs. The proposed paper will describe the model in detail, including current variations. The assumptions, governing equations, and capabilities will be addressed. Detailed examples of the model in practice will also be used.

Raquea, Steven M.↗

Graph Metric Learning Quantifies Morphological Differences between Two Genotypes of Shoot Apical Meristem Cells in Arabidopsis

We present a method for learning “spectrally descriptive” edge weights for graphs. We generalize a previously known distance measure on graphs (Graph Diffusion Distance), thereby allowing it to be tuned to minimize an arbitrary loss function. Because all steps involved in calculating this modified GDD are differentiable, we demonstrate that it is possible for a small neural network model to learn edge weights which minimize loss. We apply this method to discriminate between graphs constructed from shoot apical meristem images of two genotypes of Arabidopsis thaliana specimens: wild-type and trm678 triple mutants with cell division phenotype. Training edge weights and kernel parameters with contrastive loss produces a learned distance metric with large margins between these graph categories. We demonstrate this by showing improved performance of a simple k-nearest-neighbors classifier on the learned distance matrix. We also demonstrate a further application of this method to biological image analysis. Once trained, we use our model to compute the distance between the biological graphs and a set of graphs output by a cell division simulator. Comparing simulated cell division graphs to biological ones allows us to identify simulation parameter regimes which characterize mutant vs. wild-type Arabidopsis cells. We find that trm678 mutant cells are characterized by increased randomness of division planes and decreased ability to avoid previous vertices between cell walls.

59 BASIC BIOLOGICAL SCIENCES↗

Assessing changes in eco-productivity of wastewater treatment plants: The role of costs, pollutant removal efficiency, and greenhouse gas emissions

Highlights: • Temporal dynamics of eco-efficiency were measured for wastewater treatment plants. • Individual drivers (costs, pollutants, GHG) of eco-productivity were quantified. • Most of the plants evaluated worsened its eco-efficiency over time. • Operational costs were the main responsible of negative eco-technical change. - Abstract: Improving eco-efficiency of wastewater treatment plants (WWTPs) has been identified as being essential for achieving urban sustainability. Several previous papers have evaluated the eco-efficiency of WWTPs using data envelopment analysis (DEA) models. However, those models provided only a static assessment in that they ignored possible fluctuations over time within each plant. To overcome this temporal limitation, this paper evaluates dynamic eco-efficiency (changes in eco-productivity over time) of WWTPs using the dynamic weighted Russell directional distance model (WRDDM). This approach allows one to obtain an eco-productivity change index for each major component of the WRDDM model (costs, pollutants removal, and greenhouse gas emissions). Our results illustrate that although eco-productivity improved in half of the WWTPs we assessed, there was still potential for improving some eco-efficiency components. Moreover, operational costs and greenhouse gases emissions were the main drivers reducing eco-productivity. This paper demonstrates the importance of evaluating change in eco-productivity over time and in identifying the drivers associated with those changes, both of which can be used to support decision-making focused on the sustainability of WWTPs.

54 ENVIRONMENTAL SCIENCES↗

Tidal dissipation in the moon

Euler's equations of motion, modified to include elasticity and solid friction, were used to study the rotation of the moon. Two heuristic models for the anelasticity were considered: Q independent of frequency and Q inversely proportional to the frequency and Q inversely proportional to the frequency of the strain oscillation. Parameters in each model were estimated by weighted least squares from 9 years of lunar laser range observations. The root mean square of the postfit range residuals was 19 cm in each case. For a strain period of 1 month, the estimates of Q obtained with the two models were similar and surprisingly low: 23 + or - 6. The range of uncertaintly, + or - 6, represents our estimate of the true standard deviation of the estimate of Q, as affected by systematic errors; it is 3 times larger than the formal, statistical, standard error.

Cappallo, R. J.↗

A combination of irinotecan/cisplatinum and irinotecan/temozolomide or tumor-targeting Salmonella typhimurium A1-R arrest doxorubicin- and temozolomide-resistant myxofibrosarcoma in a PDOX mouse model

Highlights: • Myxofibrosarcoma (MFS) is the most common sarcomas in elderly patients. • Established patient-derived orthotopic xenograft (PDOX) of Myxofibrosarcoma. • The MFS PDOX models were DOX, PAZ, and TEM resistant. • Combination of IRN with either TEM or CDDP, and S. typhimurium have clinical potential for myxofibrosarcoma. Myxofibrosarcoma (MFS) is the most common sarcomas in elderly patients and is either chemo-resistant or recurs with metastasis after chemotherapy. This recalcitrant cancer in need of improved treatment. We have established a patient-derived orthotopic xenograft (PDOX) of MFS. The MFS PDOX model was established in the biceps femoris of nude mice and randomized into 7 groups of 7 mice each: control; doxorubicin (DOX); pazopanib (PAZ); temozolomide (TEM); Irinotecan (IRN); IRN combined with TEM; IRN combined with cisplatinum (CDDP) and Salmonella typhimurium A1-R (S. typhimurium A1-R). Treatment was evaluated by relative tumor volume and relative body weight. The MFS PDOX models were DOX, PAZ, and TEM resistant. IRN combined with TEM and IRN combined with CDDP were most effective on the MFS PDOX. S. typhimurium A1-R arrested the MFS PDOX tumor. There was no significant body weight loss in any group. The present study suggests that the combination of IRN with either TEM or CDDP, and S. typhimurium have clinical potential for MFS.

60 APPLIED LIFE SCIENCES↗

New error calibration tests for gravity models using subset solutions and independent data - Applied to GEM-T3

A new method has been developed to provide a direct test of the error calibrations of gravity models based on actual satellite observations. The basic approach projects the error estimates of the gravity model parameters onto satellite observations, and the results of these projections are then compared with data residual computed from the orbital fits. To allow specific testing of the gravity error calibrations, subset solutions are computed based on the data set and data weighting of the gravity model. The approach is demonstrated using GEM-T3 to show that the gravity error estimates are well calibrated and that reliable predictions of orbit accuracies can be achieved for independent orbits.

Lerch, F. J.↗