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At least 469 records · Page 26

Intracranial Effects of Artificial Gravity: A 3T MRI Study

INTRODUCTION Spaceflight associated neuro-ocular syndrome (SANS) is characterized by the development of optic disc edema, posterior globe flattening, choroidal/retinal folds and hyperopic refractive errors1. SANS is hypothesized to be a result of headward fluid shifts that invariably occurs in the microgravity environment. As a countermeasure, artificial gravity (AG) through centrifugation has been proposed to reduce this headward fluid shift, however there is no current proof of benefit. The goal of this study was to determine if the application of AG can prevent or reduce known changes in brain volumetry, internal carotid artery (ICA) stroke volume and cerebral spinal fluid (CSF) flow velocity that occurs during simulated chronic headward fluid shift using head down tilt bed rest (HDTBR) methodology2 as an indicator of countermeasure efficacy. METHODS Healthy volunteers were recruited for an IRB approved HDTBR study performed at the German Aerospace Center in Cologne, Germany. Strict six-degree HDTBR was used as a spaceflight analog to induce a continuous headward fluid shift. HDTBR was carried out for 60 days for all subjects. Short-arm centrifugation was utilized to generate AG equating to ~0.3g of acceleration at the level of the eye. The subjects were divided equally into three groups: NoAG (control; n=8), daily intermittent AG (6 x 5 min iAG; n=8), and daily continuous 30 min (cAG; n=8). All studies were performed on a single dedicated 3T MRI Scanner. Pulse-gated MRI phase-contrast flow imaging was used to quantify ICA stroke volume and peak-to-peak CSF flow velocity in the mid cerebral aqueduct. 3D-SPGR was acquired for volumetric segmentation of the brain and CSF spaces. MRI acquisitions were obtained at baseline (BDC), 14 days into HDTBR (HDTBR14), 52 days into HDTBR (HDTBR52) and 3-5 days after HDTBR (recovery, R+3/5).The data were analyzed by the mixed model, which included intervention and time (BDC, HDTBR 14, HDTBR 52, R+3/5) as the fixed effects and included subject as the random effect.RESULTS24 healthy subject volunteers (16 men, 8 women, mean age = 33 years ± 9 [standard deviation] and mean BMI = 24.3 kg/m2 ± 2.0) successfully completed all phases of the study. Strict six-degree HDTBR was characterized by progressive and statistically significant (p<.01) increases in mean combined brain and CSF volumes and mean aqueductal CSF peak-to-peak flow velocity, as well as statistically significant (p<.01) progressive decrease in mean ICA stroke volume from baseline to 52 days post intervention (Figs. 1-3). Compared to baseline, only combined brain and CSF volumes did not return to baseline values in the recovery period (p=NS). Neither iAG nor cAG exerted any significant effects on the measured MRI brain parameters as compared to HDTBR alone (p=NS). CONCLUSION Our results indicate that HDTBR at 6-degrees was effective in producing alterations in ICA stroke volume, aqueductal CSF flow velocity, and combined brain and CSF volumetric change that is associated with chronic headward fluid shift. Short duration, 30-min daily exposure to either iAG or cAG appears to be insufficient in preventing or reducing the effects of chronic HDTBR and thus may not be a suitable countermeasure as currently deployed. AG protocol modifications, including increased duration and magnitude of exposure, should be considered for future research.

L A Kramer↗

Human Thermal Assessment of Traverse and Geology Task Iterations During Simulated Lunar Extravehicular Activity

Spacewalks or extravehicular activities (EVA) in microgravity are mentally and physically demanding. Current microgravity EVAs are predominantly focused on upper body tasks on engineered surfaces; however, the introduction of gravity means that crew members during future lunar EVAs will be required to perform tasks that generate full body workloads such as navigating natural lunar terrain while conducting geological sampling. To date, only 12 people have walked on the surface of the Moon resulting in limited knowledge of suited thermal regulation under lunar-relevant physical workloads. To address this gap, a study is underway to focus on spacesuit operations with simulated lunar EVA workloads. This study presents methodology for collecting standard thermal measures during suit testing. In this pilot study, two suited subjects underwent simulated lunar EVAs using the NASA Active Response Gravity Offload System (ARGOS) to simulate the effects of partial gravity. Each lunar EVA, lasting three to five hours, included various metabolically demanding EVA tasks. Subjects donned the NASA Mark III (MK III) space suit and were offloaded to 1/6th G (lunar gravity). A subset task circuit from one of these simulations replicated an EVA traverse to a lunar crater, taking a geological sample, and returning to base. The suited subject walked one 1500 m (0% grade) and three 500 m traverses at three different grades (10, 20, 30%). Between each traverse, subjects performed geology sampling tasks (0 and 10% grade). Thermal measurements included core and skin temperature, liquid cooling garment (LCG) inlet and outlet temperature, and spacesuit gas inlet and outlet temperature and humidity. Compared to baseline core temperature (S1 = 37.07±0.32 °C, S2 = 37.27±0.01 °C) and mean skin temperature (S1 = 32.38±0.34 °C, S2 = 33.62±0.03 °C), after a 1500 m traverse, each suited subject showed an increased core temperature (S1 = 37.23±0.12 °C, S2 = 37.41±0.11°C) and decreased mean skin temperature (S1 = 32.16±0.17 °C, S2 = 31.53±1.15 °C) at a delta LCG temperature (S1 = 1.86±0.24 °C, S2 = 2.20±0.76 °C) and delta suit humidity (S1 = 9.66±1.49 %, S2 = 11.50±1.58 %). Core temperature continued to increase from compounding traverse and geology tasks (S1 = 38.04±0.03 °C, S2 = 38.1±0.02 °C) accompanied by an increase in delta LCG temperature (S1 = 2.24±0.13 °C, S2 = 2.67±0.12 °C) and delta suit humidity (S1 = 28±2.42 %, S2 = 31±2.13 %). Conversely, as the circuit progressed, mean skin temperature continued to decrease due to sustained LCG heat rejection (S1 = 30.08±0.15 °C, S2 = 30.28±0.07 °C). During the simulated EVA circuit core temperature increased to elevated values and remained elevated as heat was retained while mean skin temperature decreased due to peripheral heat offloaded to the LCG. The thermal measures collected during this study provided critical heat loading dynamics during lunar EVA tasks. Including core and skin temperatures along with suited thermal measures provides a standard data collection scheme for human thermal metrics during EVA task management. Data collected in this configuration can be used to build future lunar EVA task circuits and human thermal predictions.

Bradley Hoffmann↗

The Gravity Recovery and Interior Laboratory Mission

The Gravity Recovery and Interior Laboratory (GRAIL) mission, launched in September 2011, successfully completed its Primary Science Mission in June 2012 and is currently in Extended Mission operations. Competitively selected under a NASA Announcement of Opportunity in December 2007, GRAIL is a Discovery Program mission subject to a mandatory project cost cap. The purpose of the mission is to precisely map the gravitational field of the Moon to reveal its internal structure from crust to core, determine its thermal evolution, and extend this knowledge to other planets. The mission uses twin spacecraft flying in tandem to provide the gravity map. The GRAIL Flight System, consisting of the spacecraft and payload, was developed based on significant heritage from previous missions such an experimental U.S. Air Force satellite, the Mars Reconnaissance Orbiter (MRO) mission, and the Gravity Recovery and Climate Experiment (GRACE) mission. The Mission Operations System (MOS) was based on high-heritage multimission operations developed by NASA's Jet Propulsion Laboratory and Lockheed Martin. Both the Flight System and MOS were adapted to meet the unique challenges posed by the GRAIL mission design. This paper summarizes the implementation challenges and accomplishments of getting GRAIL ready for launch. It also discusses the in-flight challenges and experiences of operating two spacecraft, and mission results.

GRAIL↗

Modification Plans For The NASA 5.2 Second Drop Tower

A design study is currently underway to examine the possibility of converting the NASA Glenn Research Center 5.2 second drop-tower to include testing at partial gravity levels and to increase the test duration to approximately 10 seconds and the number of tests conducted in a day to over 30. This will be achieved by converting to a magnetic-levitation system to drive the test capsule. This conversion will require concessions in certain areas to enable the enhanced capability. In particular the quality of g or vibration attainable in the new design is currently unknown. This capability may trade against payload mass, volume, or test duration. The acceleration quality for partial-g studies and the launch and deceleration levels are also in the process of definition. The status of the redesign study is presented along with discussion of the critical design options. Input from the community is sought to enable optimization of the design for future combustion applications.

microgravity↗

Computational Analysis of Artificial Gravity as a Possible Countermeasure to Spaceflight Induced Bone Loss

During exploration class missions, such as to asteroids and Mars, astronauts will be exposed to reduced gravity for extended periods. Data has shown that astronauts lose bone mass at a rate of 1% to 2% a month in microgravity, particularly in lower extremities such as the proximal femur. Exercise countermeasures have not completely eliminated bone loss from long duration spaceflight missions, which leaves astronauts susceptible to early onset osteoporosis and greater risk of fracture. Introduction of the Advanced Resistive Exercise Device and other large exercise devices on the International Space Station (ISS), coupled with improved nutrition, has further minimized bone loss. However, unlike the ISS, exploration vehicles will have very limited volume and power available to accommodate such capabilities. Therefore, novel concepts like artificial gravity systems are being explored as a means to provide sufficient load stimulus to the musculoskeletal system to mitigate bone changes that may lead to early onset osteoporosis and increased risk of fracture. Currently, there is minimal data available to drive further research and development efforts to appropriately explore such options. Computational modeling can be leveraged to gain insight on the level of osteoprotection that may be achieved using artificial gravity produced by a spinning spacecraft or centrifuge. With this in mind, NASA's Digital Astronaut Project (DAP) has developed a bone remodeling model that has been validated for predicting volumetric bone mineral density (vBMD) changes of trabecular and cortical bone both for gravitational unloading condition and the equivalent of 1g daily load stimulus. Using this model, it is possible to simulate vBMD changes in trabecular and cortical bone under different gravity conditions. In this presentation, we will discuss our preliminary findings regarding if and how artificial gravity may be used to mitigate spaceflight induced bone loss.

Mulugeta, L.↗

Maturation of In-space Welding in Reduced Gravity and Reduced Pressure Environments Through Progression to Suborbital Flight Experiments

Development of in-space welding (ISW) is a key and enabling manufacturing technology as welding is currently involved in producing approximately 90% of durable goods, and this trend is expected to hold for in-space manufacturing as well. ISW is critical to a sustainable space economy. To mature in-space welding, numerous gaps must be closed since NASA has not made a weld in space in 50 years. Advancing laser beam welding (LBW) towards a suborbital flight demonstration will help mature the process for in-space assembly & manufacturing (ISAM) through demonstration in relevant environments and achieving technology readiness milestones. LBW technologies and science improved by this work will benefit in-space manufacturing, long-term sustainability of space structures & operations, and the overall space economy. Ground-based welding of aerospace hardware requires an Edisonian approach to qualify a welding process; however, this approach is infeasible for ISW qualification due to mass, volume, logistic, and cost challenges inherent to the space environment. To address this challenge, we are conducting ground and suborbital tests with partners performing parabolic flights to gather data on LBW processes and infuse them into NASA & partner missions. This progression from ground to flight experiments will elucidate relevant physics during LBW: 1) reduced gravity, 2) reduced pressure, and 3) extreme temperature. Data from post-flight evaluation and in situ instrumentation will feed integrated computational materials engineering (ICME) tools to reduce the burden of ISW infusion by establishing a link between space and terrestrial environments, ultimately accelerating the qualification of LBW in space.

in-space welding↗

Physiological adaptation to space flight

In space, adaptive physiological changes have been observed in virtually all body systems, but how far these changes progress with time is not known. Their time course demonstrates variable patterns; some systems show evidence of gradual and progressive change. Biomedical postflight data have shown that a compensatory period of readaptation to one gravity is required after space flight, with longer intervals required for longer missions. Consistent readaptation trends include orthostatic intolerance and neurovestibular difficulties. For the long-duration missions of the exploration era, it is critical to determine the extent to which deleterious changes (e.g., bone loss and possible immunological changes) can be reversed upon return to earth. Radiation protection is another critical enabling element for missions beyond low earth orbit. Radiation exposure guidelines have not been established for exploration missions. Currently our experience is insufficient to prescribe countermeasures for the stay times associated with a lunar base or a mission to Mars. Artificial gravity may provide a solution, but the level and duration of exposure necessary to prevent deconditioning must be determined. Central issues for medical care in remote settings are preventive, diagnostic, and therapeutic care and the minimization of risk.

Nicogossian, Arnauld E.↗

Phase-Controlled Magnetic Mirror for Wavefront Correction

Typically, light interacts with matter via the electric field and interaction with weakly bound electrons. In a magnetic mirror, a patterned nanowire is fabricated over a metallic layer with a dielectric layer in between. Oscillation of the electrons in the nanowires in response to the magnetic field of incident photons causes a re-emission of photons and operation as a "magnetic mirror." By controlling the index of refraction in the dielectric layer using a local applied voltage, the phase of the emitted radiation can be controlled. This allows electrical modification of the reflected wavefront, resulting in a deformable mirror that can be used for wavefront control. Certain applications require wavefront quality in the few-nanometer regime, which is a major challenge for optical fabrication and alignment of mirrors or lenses. The use of a deformable magnetic mirror allows for a device with no moving parts that can modify the phase of incident light over many spatial scales, potentially with higher resolution than current approaches. Current deformable mirrors modify the incident wavefront by using nano-actuation of a substrate to physically bend the mirror to a desired shape. The purpose of the innovation is to modify the incident wavefront for the purpose of correction of fabrication and alignment-induced wavefront errors at the system level. The advanced degree of precision required for some applications such as gravity wave detection (LISA - Laser Interferometer Space Antenna) or planet finding (FKSI - Fourier-Kelvin Stellar Interferometer) requires wavefront control at the limits of the current state of the art. All the steps required to fabricate a magnetic mirror have been demonstrated. The modification is to apply a bias voltage to the dielectric layer so as to change the index of refraction and modify the phase of the reflected radiation. Light is reflected off the device and collected by a phase-sensing interferometer. The interferometer determines the initial wavefront of the device and fore optics. A wavefront correction is calculated, and voltage profile for each nanowire strip is determined. The voltage is applied, modifying the local index of refraction of the dielectric under the nanowire strip. This modifies the phase of the reflected light to allow wavefront correction.

Hagopian, John↗

Global Bathymetric Prediction For Ocean Modeling and Marine Geophysics

We proposed to construct a complete bathymetric map of the oceans at a 3-10 km resolution by combining all of the available depth soundings collected over the past 30 years with high resolution marine gravity information provided by the Geosat, ERS-1/2, and Topex/Poseidon altimeters. Detailed bathymetry is essential for understanding physical oceanography and marine geophysics. Currents and tides are controlled by the overall shapes of the ocean basins as well as the smaller sharp ocean ridges and seamounts. Because erosion rates are low in the deep oceans, detailed bathymetry reveals the mantle convection patterns, the plate boundaries, the cooling/subsidence of the oceanic lithosphere, the oceanic plateaus, and the distribution of off-ridge volcanoes. We proposed to: (1) Accumulate all available depth soundings collected over the past 30 years; (2) Use the short wavelength (< 160 km) satellite gravity information to interpolate between sparse ship soundings; (3) Improve the resolution of the marine gravity field using enhanced estimates along repeat altimeter profiles together with the dense altimeter measurements; (4) Refine/improve bathymetric predictions using the improved resolution gravity field and also by investigating computer-intensive methods for bathymetric prediction such as inverse theory; and (5) Produce a 'Globe of the Earth' similar to the globe of Venus prepared by the NASA Magellan investigation. This will also include the best available digital land data.

Sandwell, David T.↗

Electrophoresis for biological production

Preparative electrophoresis may provide a unique method for meeting ever more stringent purity requirements. Prolonged near zero gravity in space may permit the operation of preparative electrophoresis equipment with 100 times greater throughput than is currently available. Some experiments with influenza Virus Antigen, Erythropoietin and Antihemophaliac Factor, along with process and economic projections, are briefly reviewed.

Mccreight, L. R.↗

The structure of short gravity waves on the ocean surface

A brief review is given of the salient properties of short gravity waves and the way in which their structure is modified by longer waves or swell, by variable currents, and by internal waves. It is noted that an underlying swell produces a mottled pattern in synthetic aperture radar (SAR) imagery, and an expression is derived giving the fractional modulation in backscattering cross section of the ocean surface in terms of the slope of an underlying swell, the wind direction, and the direction of swell propagation relative to the angle of observation. The expression provides the possibility in appropriate circumstances of estimating the swell slope by remote sensing, in addition to the wavelength and direction of propagation, which can be measured directly from the imagery. An account is also given of the refraction of waves in variable currents and internal waves.

Phillips, O. M.↗

Overview: Fluid acquisition and transfer

This brief overview introduced the symposium session on microgravity fluid acquisition and transfer. It states the objective of NASA efforts in this technology and the approach being taken in the technology program. The problems are outlined and various methods for low-gravity fluid acquisition and transfer are summarized. Applications for the technology are described and an assessment of the current state of the art is presented. NASA and DOD on-going and planned programs are listed.

Meserole, Jere S.↗

Agglomeration of ceramic powders

A research program directed at a critical comparison of numerical models for power agglomeration with experimental observations is currently underway. Central to this program is the quantitative characterization of the distribution of mass within an agglomerate as a function of time. Current experiments are designed to restrict agglomeration to a surface, which is oriented perpendicular to the force of gravity. These experiments are discussed with reference to: their significance to ceramic processing; artifacts which may be avoided in microgravity experiments; and the comparison of information available in real space (from optical microscopy) to that in reciprocal space (from light scattering). The principle machine requirement appears to be a need to obtain information at small scattering angles.

Cawley, James D.↗

Proton Exchange Membrane (PEM) fuel Cell for Space Shuttle

Development of a PEM fuel cell powerplant (PFCP) for use in the Space Shuttle offers multiple benefits to NASA. A PFCP with a longer design life than is delivered currently from the alkaline fuel will reduce Space Shuttle Program maintenance costs. A PFCP compatible with zero-gravity can be adapted for future NASA transportation and exploration programs. Also, the commercial PEM fuel cell industry ensures a competitive environment for select powerplant components. Conceptual designs of the Space Shuttle PFCP have resulted in identification of key technical areas requiring resolution prior to development of a flight system. Those technical areas include characterization of PEM fuel cell stack durability under operational conditions and water management both within and external to the stack. Resolution of the above issues is necessary to adequately control development, production, and maintenance costs for a PFCP.

Hoffman, William C., III↗

Development of Aluminum Composites for a Rocket Engine's Lightweight Thrust Cell

The Aerospike liquid fueled rocket engine for the X-33 aerospace vehicle consists of several thrust cells, which can comprise as much as 25% of the engine weight. The interior wall of the thrust cell chamber is exposed to high temperature combustion products and must be cooled by using liquid hydrogen. Ultimately, reducing engine weight would increase vehicle performance and allow heavier payload capabilities. Currently, the thrust cell's structural jacket and manifolds are made of stainless steel 347, which can potentially be replaced by a lighter material such as an Aluminum (Al) Metal Matrix Composites (MMC). Up to 50% weight reduction can be expected for each of the thrust cell chambers using particulate SiC reinforced Al MMC. Currently, several Al MMC thrust cell structural jackets have been produced, using cost-effective processes such as gravity casting and plasma spray deposition, to demonstrate MMC technology readiness for NASA's advanced propulsion systems.

Lee, Jonathan A.↗

Gas-Liquid Two-Phase Flows Through Packed Bed Reactors in Microgravity

The simultaneous flow of gas and liquid through a fixed bed of particles occurs in many unit operations of interest to the designers of space-based as well as terrestrial equipment. Examples include separation columns, gas-liquid reactors, humidification, drying, extraction, and leaching. These operations are critical to a wide variety of industries such as petroleum, pharmaceutical, mining, biological, and chemical. NASA recognizes that similar operations will need to be performed in space and on planetary bodies such as Mars if we are to achieve our goals of human exploration and the development of space. The goal of this research is to understand how to apply our current understanding of two-phase fluid flow through fixed-bed reactors to zero- or partial-gravity environments. Previous experiments by NASA have shown that reactors designed to work on Earth do not necessarily function in a similar manner in space. Two experiments, the Water Processor Assembly and the Volatile Removal Assembly have encountered difficulties in predicting and controlling the distribution of the phases (a crucial element in the operation of this type of reactor) as well as the overall pressure drop.

Motil, Brian J.↗

Larger, Lighter Space Telescopes by Implementing In-Space Manufacturing Concepts

There is a continuous demand for larger, lighter, and higher quality telescopes from both the astronomical and global surveillance communities one looking up and the other down. Enabling technologies must be developed and implemented that will allow this goal to be financially and technically feasible. The optical systems needed far high spatial resolution surveillance and astronomical applications require large optical, apertures with mention of future systems up to 150 meter in diameter. With traditional optical manufacturing technologies, large optical aperture means high mass and long fabrication lead times with associated high costs. Completely new approaches to optical fabrication must be developed to enable the fabrication of such optical systems. The cost and lead time associated with the fabrication of lightweight, high quality optical systems limits the feasible size of the optics. A primary factor in the launch cost of space optical systems is volume and mass. To minimize the mass of the high quality optics, optical fabricators implement materials with high specific stiffness and use honeycomb, or other structural minimization patterns, to support the optical surface; however, the structure must still be designed to survive launch loads. This sigmficantly adds to the fabrication difficulty and dramatically increases launch costs. One approach to minimizing launch volume and negating the need for the design to survive launch loads is to send the manufacturing facility and raw materials into space and perform the fabrication in-situ. We, are currently performing feasibility studies of initial concepts for inspace manufacturing of optical systems. By utilizing the micro-gravity and vacuum environment of space while eliminating the constraints defined by high launch forces and limited volume of the launch vehicle, the development of large, high quality glass membrane mirrors may be feasible. Several concepts were investigated to address the manufacturing of both optical surfaces and telescope structure. We will describe one of the primary approaches to utilize the space environment for optical manufacturing and describe initial results.

Mooney, James t.↗