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At least 469 records · Page 26

Association of particulate air pollution and acute mortality: involvement of ultrafine particles?

Recent epidemiological studies show an association between particulate air pollution and acute mortality and morbidity down to ambient particle concentrations below 100 micrograms/m3. Whether this association also implies a causality between acute health effects and particle exposure at these low levels is unclear at this time; no mechanism is known that would explain such dramatic effects of low ambient particle concentrations. Based on results of our past and most recent inhalation studies with ultrafine particles in rats, we propose that such particles, that is, particles below approximately 50 nm in diameter, may contribute to the observed increased mortality and morbidity In the past we demonstrated that inhalation of highly insoluble particles of low intrinsic toxicity, such as TiO2, results in significantly increased pulmonary inflammatory responses when their size is in the ultrafine particle range, approximately 20 nm in diameter. However, these effects were not of an acute nature and occurred only after prolonged inhalation exposure of the aggregated ultrafine particles at concentrations in the milligrams per cubic meter range. In contrast, in the course of our most recent studies with thermodegradation products of polytetrafluoroethylene (PTFE) we found that freshly generated PTFE fumes containing singlet ultrafine particles (median diameter 26 nm) were highly toxic to rats at inhaled concentrations of 0.7-1.0 x 10(6) particles/cm3, resulting in acute hemorrhagic pulmonary inflammation and death after 10-30 min of exposure. We also found that work performance of the rats in a running wheel was severely affected by PTFE fume exposure. These results confirm reports from other laboratories of the highly toxic nature of PTFE fumes, which cannot be attributed to gas-phase components of these fumes such as HF, carbonylfluoride, or perfluoroisobutylene, or to reactive radicals. The calculated mass concentration of the inhaled ultrafine PTFE particles in our studies was less than 60 micrograms/m3, a very low value to cause mortality in healthy rats. Aging of the fumes with concomitant aggregation of the ultrafine particles significantly decreases their toxicity. Since ultrafine particles are always present in the urban atmosphere, we suggest that they play a role in causing acute lung injury in sensitive parts of the population.

NASA Discipline Environmental Health↗

Structural and functional analyses of human cerebral cortex using a surface-based atlas

We have analyzed the geometry, geography, and functional organization of human cerebral cortex using surface reconstructions and cortical flat maps of the left and right hemispheres generated from a digital atlas (the Visible Man). The total surface area of the reconstructed Visible Man neocortex is 1570 cm2 (both hemispheres), approximately 70% of which is buried in sulci. By linking the Visible Man cerebrum to the Talairach stereotaxic coordinate space, the locations of activation foci reported in neuroimaging studies can be readily visualized in relation to the cortical surface. The associated spatial uncertainty was empirically shown to have a radius in three dimensions of approximately 10 mm. Application of this approach to studies of visual cortex reveals the overall patterns of activation associated with different aspects of visual function and the relationship of these patterns to topographically organized visual areas. Our analysis supports a distinction between an anterior region in ventral occipito-temporal cortex that is selectively involved in form processing and a more posterior region (in or near areas VP and V4v) involved in both form and color processing. Foci associated with motion processing are mainly concentrated in a region along the occipito-temporal junction, the ventral portion of which overlaps with foci also implicated in form processing. Comparisons between flat maps of human and macaque monkey cerebral cortex indicate significant differences as well as many similarities in the relative sizes and positions of cortical regions known or suspected to be homologous in the two species.

NASA Discipline Neuroscience↗

A psychophysiological evaluation of the perceived urgency of auditory warning signals

One significant concern that pilots have about cockpit auditory warnings is that the signals presently used lack a sense of priority. The relationship between auditory warning sound parameters and perceived urgency is, therefore, an important topic of enquiry in aviation psychology. The present investigation examined the relationship among subjective assessments of urgency, reaction time, and brainwave activity with three auditory warning signals. Subjects performed a tracking task involving automated and manual conditions, and were presented with auditory warnings having various levels of perceived and situational urgency. Subjective assessments revealed that subjects were able to rank warnings on an urgency scale, but rankings were altered after warnings were mapped to a situational urgency scale. Reaction times differed between automated and manual tracking task conditions, and physiological data showed attentional differences in response to perceived and situational warning urgency levels. This study shows that the use of physiological measures sensitive to attention and arousal, in conjunction with behavioural and subjective measures, may lead to the design of auditory warnings that produce a sense of urgency in an operator that matches the urgency of the situation.

Sound↗

Megafans of the Northern Kalahari Basin

We identify eleven megafans (partial cones of fluvial sediment, >80 km radius) in the northern Kalahari Basin, using several criteria based on VIS and IR remotely sensed data and SRTM-based surface morphology reconstructions. Two other features meet fewer criteria of the form which we class as possible megafans. The northern Kalahari megafans are located in a 1700 km arc around the southern and eastern flanks of the Angola's Bié Plateau, from northern Namibia through northwest Botswana to western Zambia. Three lie in the Owambo subbasin centered on the Etosha Pan, three in the relatively small Okavango rift depression, and five in the Upper Zambezi basin. The population includes the well-known Okavango megafan (150 km), Namibia's Cubango megafan, the largest megafan in the region (350 km long), and the largest nested group (the five major contiguous megafans on the west slopes of the upper Zambezi Valley). We use new, SRTM-based topographic roughness data to discriminate various depositional surfaces within the flat N. Kalahari landscapes. We introduce the concepts of divide megafans, derived megafans, and fan-margin rivers. Conclusions. (i) Eleven megafan cones total an area of ~190,000 sq km. (ii) Different controls on megafan size operate in the three component basins: in the Okavango rift structural controls become the prime constraint on megafan length by controlling basin dimensions. Megafans in the other les constricted basins appear to conform to classic relationships fan area, slope, and feeder-basin area. (iii) Active fans occupy the Okavango rift depression with one in the Owambo basin. The rest of the population are relict but recently active fans (surfaces are relict with respect to activity by the feeder river). (iv) Avulsive behavior of the formative river-axiomatic for the evolution of megafans-has resulted in repeated rearrangements of regional drainage, with likely effects in the study area well back into the Neogene. Divide megafans comprise the majority of the identified features, some of which have delivered water and sediment alternately to neighboring basins in the course of normal avulsion activity, likely resulting in significant changes in the hydrologies of two of the study-area subbasins. (v) Paleoclimatic inferences extracted from fluvial and lacustrine sediments therefore need to take account of avulsion-driven drainage configurations, especially where these are autogenically controlled.

Wilkinson, M. J.↗

Kinetic energy budgets during the life cycle of intense convective activity

Synoptic-scale data at three- and six-hour intervals are employed to study the relationship between changing kinetic energy variables and the life cycles of two severe squall lines. The kinetic energy budgets indicate a high degree of kinetic energy generation, especially pronounced near the jet-stream level. Energy losses in the storm environment are due to the transfer of kinetic energy from grid to subgrid scales of motion; large-scale upward vertical motion carries aloft the kinetic energy generated by storm activity at lower levels. In general, the time of maximum storm intensity is also the time of maximum energy conversion and transport.

Fuelberg, H. E.↗

'Microquasars' and the X-ray background

The recent discovery of small active nuclei (via emission lines) in normal spiral galaxies greatly expands the range of the quasar phenomenon. By using the relationship between Lx and L(H-alpha) found in more luminous Seyfert galaxies and assuming that it holds for smaller active nuclei, a bivariate X-ray luminosity function can be calculated. This luminosity function fits naturally onto the higher luminosity X-ray luminosity function derived from the HEAO-1/A2 survey. The contribution to the X-ray background from small active nuclei hiding in large spiral galaxies is greater than 15 percent.

Elvis, M.↗

Determining the rate of forest conversion in Mato Grosso, Brazil, using Landsat MSS and AVHRR data

AVHRR-LAC thermal data and Landsat MSS and TM spectral data were used to estimate the rate of forest clearing in Mato Grosso, Brazil, between 1981 and 1984. The Brazilian state was stratified into forest and nonforest. A list sampling procedure was used in the forest stratum to select Landsat MSS scenes for processing based on estimates of fire activity in the scenes. Fire activity in 1984 was estimated using AVHRR-LAC thermal data. State-wide estimates of forest conversion indicate that between 1981 and 1984, 353,966 ha + or - 77,000 ha (0.4 percent of the state area) were converted per year. No evidence of reforestation was found in this digital sample. The relationship between forest clearing rate (based on MSS-TM analysis) and fire activity (estimated using AVHRR data) was noisy (R-squared = 0.41). The results suggest that AVHRR data may be put to better use as a stratification tool than as a subsidiary variable in list sampling.

Nelson, Ross↗

Mechanical load induces sarcoplasmic wounding and FGF release in differentiated human skeletal muscle cultures

The transduction mechanism (or mechanisms) responsible for converting a mechanical load into a skeletal muscle growth response are unclear. In this study we have used a mechanically active tissue culture model of differentiated human skeletal muscle cells to investigate the relationship between mechanical load, sarcolemma wounding, fibroblast growth factor release, and skeletal muscle cell growth. Using the Flexcell Strain Unit we demonstrate that as mechanical load increases, so too does the amount of sarcolemma wounding. A similar relationship was also observed between the level of mechanical load inflicted on the cells and the amount of bFGF (FGF2) released into the surrounding medium. In addition, we demonstrate that the muscle cell growth response induced by chronic mechanical loading in culture can be inhibited by the presence of an antibody capable of neutralizing the biological activity of FGF. This study provides direct evidence that mechanically induced, sarcolemma wound-mediated FGF release is an important autocrine mechanism for transducing the stimulus of mechanical load into a skeletal muscle growth response.

NASA Center JSC↗

A survey of chromospherically active stars

Photometric and/or spectroscopic observations have been obtained of 52 late-type stars which are suspected or known to be chromospherically active. Although not all types of observations were obtained for each star, these observations include all-sky BVRI Johnson photometry, ultraviolet spectrograms, low-dispersion blue-wavelength spectrograms, and high-dispersion red-wavelength spectrograms. From the spectroscopic observations v sin i's, radial velocities, and the appearance of the Ca II H and K emission lines have been determined as well as the H-alpha line. The photometric observations indicate that chromospherically active stars have V - R and V - I color excesses. Such excesses will affect the surface fluxes determined with the surface brightness-color relationship. On the other hand all-sky BVRI photometry appears to be an excellent way to identify chromospherically active stars. A small group of moderately rapidly rotating, possibly single G8-K2 giants has been found. These stars have very modest chromospheric activity and so are not FK comae stars. A number of other unusual chromospherically active stars are identified.

Fekel, F. C.↗

A review of the 11-year solar cycle, the QBO, and the atmosphere relationship

The papers published by Labitzke (1987) and by Labitzke and Van Loon (1988) indicated that the separation of Winter stratospheric data according to the phase of the Quasi-Biennial Oscillation (Q.B.O.) led to a largely improved relationship with the 11 year solar cycle. Since then, this possible relationship has been studied and extended from the surface to the lower thermosphere and its extension to other seasons is in progress. An opportunity is provided to review the state of the problem and to attempt to give a general view of the experimentally observed responses of the atmosphere to solar activity, when considering the phases of the Q.B.O. After a brief recall of the relationship discovered in the winter stratosphere, its extension downwards, upwards and to the other seasons are successively reviewed. The existing models are not adequate right now to represent the solar influence as they only take into account the change in UV flux, but before being able to use the large scale dynamics in a coupled radiative photochemical model, one needs to understand the mechanism able to explain the forcing from the lower atmosphere or the surface which could be induced by a change in solar activity.

Chanin, M. L.↗

Relationship Between Rainfall in the Northern Hemisphere and Impulses of the Torque in the Sun's Motion

The analysis of major change in the angular momentum of the sun's irregular motion about the barycenter of the solar system, represented by extrema in the running variance of impulses of the torque (IOT), discloses a connection with both extrema in the Gleissberg cycle of secular sunspot activity and maxima in the thickness of varves from Lake Saki, Crimea. This significant relationship can be traced back to the 7th century. Further inquiries link the running variance in IOT to rainfall over central Europe, England, Wales, eastern United States, and India, as well as to temperature in Europe. This significant correlation covers more than 130 years.

Landscheidt, T.↗

COVID-19 Lockdowns Drive Decline in Active Fires in Southeastern United States

Fire is a common ecosystem process in forests and grasslands worldwide. Increasingly, ignitions are controlled by human activities either through suppression of wildfires or intentional ignition of prescribed fires. The Southeastern United States leads the nation in prescribed fire, burning ca. 80% of the countries extent annually. The COVID-19 pandemic radically changed human behavior as workplaces implemented social-distancing guidelines and provided an opportunity to evaluate relationships between humans and fire as fire management plans were postponed or cancelled. Using active fire data from satellite-based observations, we found that in the Southeastern United States, COVID-19 led to a 21% reduction in fire activity compared to the 2003-2019 average. The reduction was more pronounced for federally managed lands, up to 41% below average compared to the past 20-years (38% below average compared to the past decade). Declines in fire activity were partly affected by an unusually wet February before the COVID-19 shutdown began in mid-March 2020. Despite the wet spring, the predicted number of active fire detections was still lower than expected, confirming a COVID-19 signal on ignitions. In addition, prescribed fire management statistics, reported by US federal agencies, confirmed the satellite observations, and showed that following the wet February and before the mid-March COVID-19 shutdown, cumulative burned area was approaching record highs across the region. With fire return intervals in the Southeastern United States as frequent as 1-2 years, COVID-19 fire impacts will contribute to an increasing backlog in necessary fire management activities, affecting biodiversity and future fire danger.

Biological Sciences↗

Fundamental investigation of stress corrosion cracking

Two principle areas studied were stress corrosion crack growth rates of a titanium alloy in liquid environments containing halide ions and pitting corrosion of titanium in bromide solutions. Two initial assumptions were made, that the rate of propagation was controlled by a macroscopic solution parameter and that this parameter was viscosity. A series of solutions were prepared using lithium chloride as the solute and water, methanol, glycerin, formic acid, acetone, dimethyl sulphoxide, etc. As solvents, these solutions were prepared with a 5:1 solvent-solute ratio. Viscosity was varied by changing the temperature and it was found: (1) In all solvents the velocity of cracking was proportional to the reciprocal of the viscosity. (2) Each solvent gave a separate relationship, (3) The temperature dependence and numerical values for the apparent activation energy of cracking and viscosity were the same.

Beck, T. R.↗

Imaging of X-ray aurorae from Spacelab

The Atmospheric X-ray Emission Telescope (AXET) is designed to image and measure the spatial, temporal, and spectral distributions of X-ray aurorae produced in the upper atmosphere by precipitating energetic electrons. The bremsstrahlung-produced X radiation penetrates to stratospheric depths where it can modify ozone, conductivity, and other critical atmospheric parameters. Remote sensing of this radiation from topside will provide vital data on solar-terrestrial relationships and mechanisms that could help trigger tropospheric response to solar activity. The X rays also provide direct information concerning the dynamics of radiation-belt processes within the magnetosphere. AXET is designed to detect sources up to 50 keV and to image them below 25 keV by means of directionally sensitive proportional counters with passive collimators. It will be mounted in the Space Shuttle on a single fixed platform designed to optimize viewing conditions for the anticipated orbits and aspects of early Spacelab missions.

Goldberg, R. A.↗

A survey of coronal holes and their solar wind associations throughout sunspot cycle 20

Space-borne X-ray and XUV observations during the period 1963-74 (corresponding approximately with solar cycle 20) have been used to investigate the relationship between the occurrence and variability of coronal holes and solar activity, i.e., the solar wind. Results indicate that polar holes (prominent at solar minimum) decreased in area as solar activity increased. The equatorial holes were also small during this period and persisted for one or two solar rotations only. Solar wind streams in excess of 500 km/s were associated with coronal holes at less than 40 deg latitude, although solar coronal holes appear to have no associated wind streams at earth.

Broussard, R. M.↗

Relationship between the kinetic energy budget and intensity of convection

Synoptic data collected over the eastern United States during the fourth Atmospheric Variability Experiment, April 24 and 25, 1975, is used to study the relationship between the kinetic energy budget and the intensity of convective activity. It is found that areas of intense convective activity are also major centers of kinetic energy activity. Energy processes increase in magnitude with an increase in convection intensity. Large generation of kinetic energy is associated with intense convection, but large quantities of energy are transported out of the area of convection. The kinetic energy budget associated with grid points having no convection differs greatly from the budgets of the three categories of convection. Weak energy processes are not associated with convection.

Fuelberg, H. E.↗

Planetary wave coupling between the troposphere and the middle atmosphere as a possible sun-weather mechanism

The possibility of planetary wave coupling between the troposphere and solar-induced alterations in the upper atmosphere providing a viable mechanism for giving rise to sun-weather relationships is investigated. Some of the observational evidence for solar-activity-induced effects on levels of the upper atmosphere ranging from the thermosphere down to the lower stratosphere are reviewed. It is concluded that there is evidence for such effects extending down to the middle stratosphere and below. Evidence is also reviewed that these effects are due to changes in solar ultraviolet emission during disturbed solar conditions. A theoretical planetary wave model is then used to see at what levels in the upper atmosphere moderate changes in the mean zonal wind state would result in tropospheric changes. It is concluded that changes in the mean zonal flow of about 20% at levels in the vicinity of 35 km or below would give rise to changes in the tropospheric planetary wave pattern that are less than but on the same order as the observed interannual variability in the tropospheric wave pattern at middle and high latitudes.

Geller, M. A.↗