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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 469 records · Page 26

Characterization of Humanized Mouse Model of Organophosphate Poisoning and Detection of Countermeasures via MALDI-MSI

Organophosphoate (OP) chemicals are known to inhibit the enzyme acetylcholinesterase (AChE). Studying OP poisoning is difficult because common small animal research models have serum carboxylesterase, which contributes to animals’ resistance to OP poisoning. Historically, guinea pigs have been used for this research; however, a novel genetically modified mouse strain (KIKO) was developed with nonfunctional serum carboxylase (Es1 KO) and an altered acetylcholinesterase (AChE) gene, which expresses the amino acid sequence of the human form of the same protein (AChE KI). KIKO mice were injected with 1xLD50 of an OP nerve agent or vehicle control with or without atropine. After one to three minutes, animals were injected with 35 mg/kg of the currently fielded Reactivator countermeasure for OP poisoning. Postmortem brains were imaged on a Bruker RapifleX ToF/ToF instrument. Data confirmed the presence of increased acetylcholine in OP-exposed animals, regardless of treatment or atropine status. More interestingly, we detected a small amount of Reactivator within the brain of both exposed and unexposed animals; it is currently debated if reactivators can cross the blood–brain barrier. Further, we were able to simultaneously image acetylcholine, the primary affected neurotransmitter, as well as determine the location of both Reactivator and acetylcholine in the brain. This study, which utilized sensitive MALDI-MSI methods, characterized KIKO mice as a functional model for OP countermeasure development.

2-PAM↗

Processing, Microstructure, and Properties of Bimetallic Steel-Ni Alloy Powder HIP

This work explores technical feasibility in hot isostatic pressing (HIP) manufacturing of an integral bimetallic component using steel and Ni alloy powder for supercritical carbon dioxide (sCO2) turbomachinery. Lab-scale bimetallic HIP specimens using HAYNES® 282® and SS316L or SS415 powder are investigated in powder configuration, heat treatment, microstructure, and tensile properties up to 400 °C. Interdiffusion profiles at dissimilar alloy interfaces caused by HIP cycle is predicted by DICTRA simulations and validated by electron probe microanalysis (EPMA). The interdiffusion distance of most elements is around 100 μm, while C and N have a higher interdiffusion distance. Dense distribution of Ti-rich carbonitrides and alumina particles are found to decorate prior particle boundaries near joining interface on the 282 side, affecting tensile strength across interface as well as tensile failure location. A higher amount of excessive carbonitride formation near interface is observed in SS316L/282 than in SS415/282, which is consistent with the predicted greater degree of interdiffusion effect in SS316L/282. Typical HAYNES® 282® heat treatment condition is applicable to 282/SS316L and 282/SS415 combinations, resulting in a higher strength than cast CF8M and CA6NM. A pilot-scale bimetallic SS415/282 pipe is then demonstrated to show the promise of scaleup.

36 MATERIALS SCIENCE↗

Bolide Infrasound Signal Morphology and Yield Estimates: A Case Study of Two Events Detected by a Dense Acoustic Sensor Network

Two bolides (2016 June 2 and 2019 April 4) were detected at multiple regional infrasound stations, with many of the locations receiving multiple detections. Analysis of the received signals was used to estimate the yield, location, and trajectory, as well as the type of shock that produced the received signal. The results from the infrasound analysis were compared with ground-truth information that was collected through other sensing modalities. This multimodal framework offers an expanded perspective on the processes governing bolide shock generation and propagation. The majority of signal features showed reasonable agreement between the infrasound-based interpretation and the other observational modalities, though the yield estimate from the 2019 bolide was significantly lower using the infrasound detections. There was also evidence suggesting that one of the detections was from a cylindrical shock that was initially propagating upward, which is unusual though not impossible.

79 ASTRONOMY AND ASTROPHYSICS↗

A study of the utilization of ERTS-1 data from the Wabash River Basin

The author has identified the following significant results. For the urban land use analysis project, classification results were good to excellent for the following classes: single family residential, commercial/industrial, cloud, cloud shadow, trees, and water. Grassy areas were defined fairly well, but residential areas located between multi-family residential and single-family residential were misclassified as grassy. Residential areas dominated by tree cover, termed wooded residential, were unable to be classified in a single class. Data points in such areas were classified randomly as either grassy or trees.

Landgrebe, D. A.↗

Icelandic geothermal activity and the mercury of the Greenland icecap.

Aerometric studies concerning the level of atmospheric mercury were conducted at a number of sites in Iceland during June and July 1972. Samples from widely separated locations yielded Hg concentrations well above the range commonly cited for unpolluted air. Atmospheric mercury may be introduced in part by degassing fluid magmas. However, the release from fine ash could also serve as a vehicle. It is pointed out that from the mid-17th century to the present, Iceland has recorded nearly 50 volcanic eruptions.

Siegel, B. Z.↗

Studies of acceleration processes in the corona using ion measurements on the solar probe mission

The energy spectra and composition of particles escaping from the Sun provide essential information on mechanisms responsible for their acceleration, and may also be used to characterize the regions where they are accelerated and confined and through which they propagate. The suprathermal energy range, which extends from solar wind energies (approximately 1 KeV) to about 1 MeV/nucleon, is of special interest to studies of nonthermal acceleration processes because a large fraction of particles is likely to be accelerated into this energy range. Data obtained from near earth observations of particles in the suprathermal energy range are reviewed. The necessary capabilities of an a ion composition experiment in the solar probe mission and the required ion measurements are discussed. A possible configuration of an instrument consisting of an electrostatic deflection system, modest post acceleration, and a time of flight versus energy system is described as well as its possible location on the spacecraft.

Gloeckler, G.↗

The use of surface reflections in lunar seismograms

The use of polarization filters is demonstrated on lunar seismograms. Body-wave arrivals from artificial impacts are identified as surface reflections, which may be used for improving our knowledge of the lunar interior or to relocate surface events if an approximate location is known as well as an approximate model.

Jarosch, H. S.↗

The moon - Sources of the crustal magnetic anomalies

Evidence from low altitude Apollo 16 subsatellite magnetometer measurements of the lunar near side is presented showing that basin and crater ejecta are major sources of lunar magnetic anomalies. It is found that anomalies increase in amplitude and complexity with a decrease in altitude, indicating localized, near surface sources, but it is also found that anomalies are less intense and numerous over maria than over highlands. Also, few anomalies are found to be associated with young craters, eliminating direct shock magnetization as a possible cause, but numerous anomalies are present over formations not flooded by mare basalts. The largest observed anomaly is well correlated with the location of a conspicuous deposit, believed to be crater ejecta, with a mean magnetization level of 5.2 + or - 2.4 x 10 to the -2 electromagnetic units/g. It is also concluded that the magnetization of the lunar crust must have taken place over a period of over one billion years.

Hood, L. L.↗

Clear air turbulence studies with microwave radiometers

The flight testing of two passive microwave radiometers for the detection of clear air turbulence (CAT) is discussed. A 55.3 GHz radiometer was used to measure altitude temperature profiles, and a 180 GHz radiometer was used for monitoring line-of-sight integrated water vapor content. The sequence of altitude temperature profiles, spaced 17 seconds apart (3.5 km), enable inversion layer and tropopause properties to be studied. On some occasions, the altitude distribution of CAT severity correlated well with inversion layer location. On other occasions, turbulence was not located within 55.3 GHz measured layers, possibly indicating cases of topography-generated CAT, where inversion layer would not necessarily be expected. Evidence was obtained supporting the hypothesis that CAT is generated within layers containing levels of wind shear that cannot be supported by the layer's lapse rate; i.e., that Kelvin-Helmholtz wave breakdown can generate CAT. The 180 GHz radiometer failed to warn of CAT events. It is suggested that the radiometer's sensitivity (1 K) was inadequate for detecting the small variations in line-of-sight water vapor content.

Gary, B. L.↗

The distant bow shock and magnetotail of Venus - Magnetic field and plasma wave observations

An examination of the magnetic field and plasma wave data obtained by the Pioneer Venus orbiter in the wake region behind Venus discloses a well developed bow shock whose location is similar to that observed on previous missions in contrast to the dayside bow shock. Venus also has a well developed magnetotail in which the field strenght is enhanced over magnetosheath values and in which the magnetic field is aligned approximately with the solar wind direction. The boundary between magnetosheath and magnetotail is also marked by a change in the plasma wave spectrum.

Russell, C. T.↗

Confinement and acceleration of cosmic rays in galactic superbubbles

The role of the newly discovered galactic superbubbles on the confinement and acceleration of cosmic rays is examined. It is shown that these structures naturally account for the lifetime and the local origin of the cosmic rays, as well as for the location of galactic gamma-ray sources not associated with pulsars.

Kafatos, M.↗

AFWAL space control technology program

An overview of space oriented control technology programs which are applicable to flexible large space structures is presented. The spacecraft control activity is interdisciplinary with activities in structures, structural dynamics and control brought together. The large flexible structures to be controlled have many physical factors that influence the final controllability of the vehicle. Factors are studied such as rigidity of both structural elements and joints, damping inherent in both material as well as discrete dampers located throughout the structure, and the bandwidth of both sensors and actuators used to sense motion and control it. Descriptions of programs both in-house and contracted are given.

Hoehne, V. O.↗

Simulating transitional flow and heat transfer over the flat plate and circular cylinder using a K-epsilon turbulence model

A boundary layer computer code, called TEXSTAN, has been used to simulate external, transitional, fluid flow and heat transfer over the flat plate and circular cylinder. Turbulence modeling was accomplished by using a low-Reynolds number K-epsilon turbulence model. The study was made for free-stream turbulence intensities less than 15 percent. The comparison of the flat plate heat transfer predictions to experimental data showed good agreement, for the location of transition as well as in the heat transfer coefficient. The typical discrepancy in predicting the heat transfer coefficient was less than 5 percent of the measured value.

Sullivan, T. J.↗

Grid convergence for adaptive methods

The ability of adaptive methods to obtain accurate results is examined using two different Euler solvers for a near-sonic flow containing several important flow features. It is shown that the accuracy obtained can be greatly affected by the lack of resolution of smooth portions of the flow caused by adapting only to the more prevalent flow features such as discontinuities. In particular, common methods of adaptation can lead to results in which shocks are well resolved but whose locations are highly inaccurate due to the lack of resolution of the smoother regions. An explanation for this behavior is given and a correction is proposed.

Warren, Gary P.↗

Orbit-determination performance of Doppler data for interplanetary cruise trajectories. Part 1: Error analysis methodology

An error covariance analysis methodology is used to investigate different weighting schemes for two-way (coherent) Doppler data in the presence of transmission-media and observing-platform calibration errors. The analysis focuses on orbit-determination performance in the interplanetary cruise phase of deep-space missions. Analytical models for the Doppler observable and for transmission-media and observing-platform calibration errors are presented, drawn primarily from previous work. Previously published analytical models were improved upon by the following: (1) considering the effects of errors in the calibration of radio signal propagation through the troposphere and ionosphere as well as station-location errors; (2) modelling the spacecraft state transition matrix using a more accurate piecewise-linear approximation to represent the evolution of the spacecraft trajectory; and (3) incorporating Doppler data weighting functions that are functions of elevation angle, which reduce the sensitivity of the estimated spacecraft trajectory to troposphere and ionosphere calibration errors. The analysis is motivated by the need to develop suitable weighting functions for two-way Doppler data acquired at 8.4 GHz (X-band) and 32 GHz (Ka-band). This weighting is likely to be different from that in the weighting functions currently in use; the current functions were constructed originally for use with 2.3 GHz (S-band) Doppler data, which are affected much more strongly by the ionosphere than are the higher frequency data.

Ulvestad, J. S.↗

Issues in designing transport layer multicast facilities

Multicasting denotes a facility in a communications system for providing efficient delivery from a message's source to some well-defined set of locations using a single logical address. While modem network hardware supports multidestination delivery, first generation Transport Layer protocols (e.g., the DoD Transmission Control Protocol (TCP) (15) and ISO TP-4 (41)) did not anticipate the changes over the past decade in underlying network hardware, transmission speeds, and communication patterns that have enabled and driven the interest in reliable multicast. Much recent research has focused on integrating the underlying hardware multicast capability with the reliable services of Transport Layer protocols. Here, we explore the communication issues surrounding the design of such a reliable multicast mechanism. Approaches and solutions from the literature are discussed, and four experimental Transport Layer protocols that incorporate reliable multicast are examined.

Dempsey, Bert J.↗

Comparisons of satellite retrieved layer temperature and correlative radiosonde data

A quantitative analysis of satellite temperature accuracy is performed using an extensive correlative data set for selected radiosonde stations along eastern North America from midlatitudes through the tropics. The satellite-retrieved layer temperature agrees with the radiosonde temperature within +/- 1.2 K globally, although variations are observed with layers as well as radiosonde station locations. The satellite measurement show lowest sensitivity and accuracy for the Layer 7 temperature in general.

Lee, H. S.↗

Fully coupled resonant-triad interaction in an adverse-pressure-gradient boundary layer

The nonlinear resonant-triad interaction, proposed by Raetz (1959), Craik (1971), and others for a Blasius boundary layer, is analyzed here for an adverse-pressure-gradient boundary layer. We assume that the adverse pressure gradient is in some sense weak and, therefore, that the instability growth rate is small. This ensures that there is a well-defined critical layer located somewhere within the flow and that the nonlinear interaction is effectively confined to that layer. The initial interaction is of the parametric resonance type, even when the modal amplitudes are all of the same order. This means that the oblique instability waves exhibit faster than exponential growth and that the growth rate of the two-dimensional mode remains linear. However, the interaction and the resulting growth rates become fully coupled, once oblique-mode amplitudes become sufficiently large, but the coupling terms are now quartic, rather than quadratic as in the Craik (1971) analysis. More importantly, however, new nonlinear interactions, which were not present in the Craik-type analyses, now come into play. These interactions eventually have a dominant effect on the instability wave development.

Goldstein, M. E.↗