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At least 469 records · Page 26

Analytical, experimental, and Monte Carlo system response matrix for pinhole SPECT reconstruction

Purpose: To assess the performance of two approaches to the system response matrix (SRM) calculation in pinhole single photon emission computed tomography (SPECT) reconstruction. Methods: Evaluation was performed using experimental data from a low magnification pinhole SPECT system that consisted of a rotating flat detector with a monolithic scintillator crystal. The SRM was computed following two approaches, which were based on Monte Carlo simulations (MC-SRM) and analytical techniques in combination with an experimental characterization (AE-SRM). The spatial response of the system, obtained by using the two approaches, was compared with experimental data. The effect of the MC-SRM and AE-SRM approaches on the reconstructed image was assessed in terms of image contrast, signal-to-noise ratio, image quality, and spatial resolution. To this end, acquisitions were carried out using a hot cylinder phantom (consisting of five fillable rods with diameters of 5, 4, 3, 2, and 1 mm and a uniform cylindrical chamber) and a custom-made Derenzo phantom, with center-to-center distances between adjacent rods of 1.5, 2.0, and 3.0 mm. Results: Good agreement was found for the spatial response of the system between measured data and results derived from MC-SRM and AE-SRM. Only minor differences for point sources at distances smaller than the radius of rotation and large incidence angles were found. Assessment of the effect on the reconstructed image showed a similar contrast for both approaches, with values higher than 0.9 for rod diameters greater than 1 mm and higher than 0.8 for rod diameter of 1 mm. The comparison in terms of image quality showed that all rods in the different sections of a custom-made Derenzo phantom could be distinguished. The spatial resolution (FWHM) was 0.7 mm at iteration 100 using both approaches. The SNR was lower for reconstructed images using MC-SRM than for those reconstructed using AE-SRM, indicating that AE-SRM deals better with the projection noise than MC-SRM. Conclusions: The authors' findings show that both approaches provide good solutions to the problem of calculating the SRM in pinhole SPECT reconstruction. The AE-SRM was faster to create and handle the projection noise better than MC-SRM. Nevertheless, the AE-SRM required a tedious experimental characterization of the intrinsic detector response. Creation of the MC-SRM required longer computation time and handled the projection noise worse than the AE-SRM. Nevertheless, the MC-SRM inherently incorporates extensive modeling of the system and therefore experimental characterization was not required.

62 RADIOLOGY AND NUCLEAR MEDICINE↗

SU-F-T-322: A Comparison of Two Si Detectors for in Vivo Dosimetry

Purpose: To compare two types of semiconductor detectors for in vivo dosimetry by their dependence from various parameters in different conditions. Methods: QED yellow (Sun Nuclear) and EDP (Scanditronix) Si detectors were radiated by a Varian Clinac 2300 ix with 6 and 18 MV energies. 10 cm thickness water equivalent phantom consisted of 30×30 cm{sup 2} squared plates was used for experiments. Dose dependencies for different beam angles (0 – 180°), field size (3–40 cm), dose (50 – 300 MU), and dose rates (50 – 300 MU/min) were obtained and calibrated with Standard Farmer chamber (PTW). Results: Reproducibility, linearity, dose rate, angular dependence, and field size dependence were obtained for QED and EDP. They show no dose-rate dependence in available clinical dose rate range (100–600 MU/min). Both diodes have linear dependence with increasing the dose. Therefore even in case of high radiation therapy (including total body irradiation) it is not necessary to apply an additional correction during in vivo dosimetry. The diodes have different behavior for angular and field size dependencies. QED diode showed that dose value is stable for beam angles from 0 to 60°, for 60–180° correction factor has to be applied for each beam angle during in vivo measurements. For EDP diode dose value is sensitive to beam angle in whole range of angles. Conclusion: The study shows that QED diode is more suitable for in vivo dosimetry due to dose value independence from incident beam angle in the range 0–60°. There is no need in correction factors for increasing of dose and dose rate for both diodes. The next step will be to carry out measurements in non-standard conditions of total body irradiation. After this modeling of these experiments with Monte Carlo simulation for comparison calculated and obtained data is planned.

60 APPLIED LIFE SCIENCES↗

Measuring SNM Isotopic Distributions using FRAM

The first group of slides provides background information on the isotopic composition of plutonium. It is shown that 240 Pu is the critical isotope in neutron coincidence/multiplicity counting. Next, response function analysis to determine isotopic composition is discussed. The isotopic composition can be determined by measuring the net peak counts from each isotope and then taking the ratio of the counts for each isotope relative to the total counts for the element. Then FRAM (Fixed energy Response function Analysis with Multiple efficiencies) is explained. FRAM can control data acquisition, automatically analyze newly acquired data, analyze previously acquired data, provide information on the quality of the analysis, and facilitate analysis in unusual situations (non-standard energy calibrations, gamma rays from non-SNM isotopes, poor spectra (within limits)).

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

Closeout Briefing for PSL Technical Survey of MSTS SCP (JASPER) [PowerPoint]

NNSA Order 56XB (Chapter 13.2) requires the Primary Standards Laboratory (PSL) to perform technical surveys on the integrated contractors participating in the NNSA Standards and Calibration Program. In addition to Chapter 13.2, the surveys check for compliance with ISO/IEC 17025 and the PSLM. The PSL Technical Survey is a joint activity of the NNSA and the PSL. The PSL is responsible for the technical portion of the survey and the NNSA is responsible for the quality portion. The Technical Survey report is issued by the NNSA.

42 ENGINEERING↗

Enabling Efficient Surveillance, Control, and Automation of Geothermal Operations with Advanced Predictive Analytics

Automation and control of geothermal energy production and operations require reliable and efficient predictive tools. While physics-based simulation offers a comprehensive tool for predicting energy production performance in geothermal systems, predicting the behavior of geothermal reservoirs involves complex multi-physics processes with coupling effects, highly uncertain input parameters and subsurface descriptions. Moreover, building, running, and integrating simulation models into standard model calibration and optimization workflows entail significant technical and computational efforts. An emerging alternative to physics-based simulation is data-driven predictive analytics models that have gained popularity in energy industry. In this report, we develop novel predictive models for integration into real-time fault diagnosis and model predictive control algorithms to improve the efficiency of energy production operations in geothermal reservoirs. The report includes two major research Thrust Areas, that is, the surface power plant and the subsurface reservoir.

15 GEOTHERMAL ENERGY↗

Synchrotron X-ray Microdiffraction and Fluorescence Imaging of Mineral and Rock Samples

In this paper, we describe a detailed procedure for acquiring and processing x-ray microfluorescence (μXRF), and Laue and powder microdiffraction two-dimensional (2D) maps at beamline 12.3.2 of the Advanced Light Source (ALS), Lawrence Berkeley National Laboratory. Measurements can be performed on any sample that is less than 10 cm x 10 cm x 5 cm, with a flat exposed surface. The experimental geometry is calibrated using standard materials (elemental standards for XRF, and crystalline samples such as Si, quartz, or Al 2 O 3 for diffraction). Samples are aligned to the focal point of the x-ray microbeam, and raster scans are performed, where each pixel of a map corresponds to one measurement, e.g. , one XRF spectrum or one diffraction pattern. The data are then processed using the in-house developed software XMAS, which outputs text files, where each row corresponds to a pixel position. Representative data from moissanite and an olive snail shell are presented to demonstrate data quality, collection, and analysis strategies.

36 MATERIALS SCIENCE↗

Cosmology Large Angular Scale Surveyor (CLASS): 90 GHz Telescope Pointing, Beam Profile, Window Function, and Polarization Performance

The Cosmology Large Angular Scale Surveyor (CLASS) is a telescope array that observes the cosmic microwave background (CMB) over ∼75% of the sky from the Atacama Desert, Chile, at frequency bands centered near 40, 90, 150, and 220 GHz. CLASS measures the large angular scale CMB polarization to constrain the tensor-to-scalar ratio and the optical depth to last scattering. This paper presents the optical characterization of the 90 GHz telescope. Observations of the Moon establish the pointing while dedicated observations of Jupiter are used for beam calibration. The standard deviations of the pointing error in azimuth, elevation, and boresight angle are 1$^{'}_.$3, 2$^{'}_.$1, and 2$^{'}_.$0, respectively, over the first 3 yr of observations. This corresponds to a pointing uncertainty ∼7% of the beam’s full width at half-maximum (FWHM). The effective azimuthally symmetrized instrument 1D beam estimated at 90 GHz has an FWHM of 0$^°_.$620 ± 0$^°_.$003 and a solid angle of 138.7 ± 0.6(stats.) ± 1.1(sys.) μsr integrated to a radius of 4°. The corresponding beam window function drops to $b^2_ℓ$ = 0.93, 0.71, 0.14 at ℓ = 30, 100, 300, respectively. Far-sidelobes are studied using detector-centered intensity maps of the Moon and measured to be at a level of 10 −3 or below relative to the peak. The polarization angle of Tau A estimated from preliminary survey maps is 149°.6 ± 0°.2(stats.) in equatorial coordinates. The instrumental temperature-to-polarization (T → P) leakage fraction, inferred from per-detector demodulated Jupiter scan data, has a monopole component at the level of 1.7 × 10 −3 , a dipole component with an amplitude of 4.3 × 10 −3 , with no evidence of quadrupolar leakage.

79 ASTRONOMY AND ASTROPHYSICS↗

Fraunhofer line-dept sensing applied to water

An experimental Fraunhofer line discriminator is basically an airborne fluorometer, capable of quantitatively measuring the concentration of fluorescent substances dissolved in water. It must be calibrated against standards and supplemented by ground-truth data on turbidity and on approximate vertical distribution of the fluorescent substance. Quantitative use requires that it be known in advance what substance is the source of the luminescence emission; qualitative sensing, or detection of luminescence is also possible. The two approaches are fundamentally different, having different purposes, different applications, and different instruments. When used for sensing of Rhodamine WT dye in coastal waters and estuaries, the FLD is sensing in the spectral region permitting nearly maximum depth of light penetration.

Stoertz, G. E.↗

Monitoring forest land from high altitude and from space

Forest inventory, forest stress, and standardization and calibration studies are presented. These include microscale photointerpretation of forest and nonforest land classes, multiseasonal film densities for automated forest and nonforest land classification, trend and spread of bark beetle infestations from 1968 through 1971, aerial photography for determining optimum levels of stand density to reduce such infestations, use of airborne spectrometers and multispectral scanners for previsual detection of Ponderosa pine trees under stress from insects and diseases, establishment of an earth resources technology satellite test site in the Black Hills and the identification of natural resolution targets, detection of root disease impact on forest stands by sequential orbital and suborbital multispectral photography, and calibration of color aerial photography.

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Piston manometer as an absolute standard for vacuum-gauge calibration.

Determination of total pressure in a calibration volume by measuring the force on a thin circular disk, of accurately-known area, that is freely suspended in a hole in the container wall, so that the disk is substantially flush with the wall. The disk almost fills the hole, so that there is a narrow annular gap. A continuous flow of calibrating gas, injected into the container in order to maintain a desired pressure, passes through the annular gap to a diffusion pump. The ratio of pressures on the two faces of the disk is on the order of 100:1, so that downstream pressure need be known only nominally in order to deduce the upstream pressure. Force on the disk is measured by a balance that is calibrated in situ with dead weights. In one arrangement, pressures in the range from 10 to 500 microtorr were measured with an estimated probable error of (1 microtorr + 1%).

Warshawsky, I.↗

Piston manometer as an absolute standard for vacuum-gauge calibration.

Determination of the total pressure in a calibration volume by measuring the force on a thin circular disk, of accurately known area, that is freely suspended in a hole in the container wall, so that the disk is substantially flush with the wall. The disk almost fills the hole, so that there is a narrow annular gap. A continuous flow of calibrating gas, injected into the container in order to maintain a desired pressure, passes through the annular gap to a diffusion pump. The ratio of pressures on the two faces of the disk is of the order of 100:1, so that downstream pressure need be known only nominally in order to deduce the upstream surface. Force on the disk is measured by a balance that is calibrated in situ with dead weights. In one arrangement, pressures in the range from 10 to 500 microtorr were measured with an estimated probable error of (1 microtorr + 1%).

Warshawsky, I.↗

Piston manometer as an absolute standard for vacuum-gage calibration in the range 2 to 500 millitorr

A thin disk is suspended, with very small annular clearance, in a cylindrical opening in the base plate of a calibration chamber. A continuous flow of calibration gas passes through the chamber and annular opening to a downstream high vacuum pump. The ratio of pressures on the two faces of the disk is very large, so that the upstream pressure is substantially equal to net force on the disk divided by disk area. This force is measured with a dynamometer that is calibrated in place with dead weights. A probable error of + or - (0.2 millitorr plus 0.2 percent) is attainable when downstream pressure is known to 10 percent.

Warshawsky, I.↗

In situ transfer standard for ultrahigh vacuum gage calibration

A compact insitu calibration assembly, for ultrahigh vacuum gauges is described. The system depends on the repeatable generation of a specific gas pressure by the dissociation of a solid solution chemical compound when subjected to a given temperature. A precise temperature measurement is related to the pressure generated within the vacuum by the properties of the solid solution compound. this accurately establishes the gas pressure which in turn is used to calibrate a vacuum gauge. Also included is a metering orifice used in the calibration system and which is made movable to facilitate the degassing bakeout required in ultrahigh vacuum devices.

Outlaw, R. A.↗

Monitoring forest land from high altitude and from space

The significant findings are reported for remote sensing of forest lands conducted during the period October 1, 1965 to December 31, 1972. Forest inventory research included the use of aircraft and space imagery for forest and nonforest land classification, and land use classification by automated procedures, multispectral scanning, and computerized mapping. Forest stress studies involved previsual detection of ponderosa pine under stress from insects and disease, bark bettle infestations in the Black Hills, and root disease impacts on forest stands. Standardization and calibration studies were made to develop a field test of an ERTS-matched four-channel spectrometer. Calibration of focal plane shutters and mathematical modeling of film characteristic curves were also studied. Documents published as a result of all forestry studies funded by NASA for the Earth Resources Survey Program from 1965 through 1972 are listed.

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Determination of left ventricular size and shape

Significant advances have occurred over the past 15 years in the ability to measure ventricular dimensions. Angiocardiography still remains the most reliable method for overall determination of chamber size and shape and serves as a standard for calibration or comparison for newer methods. Improvements in the use of radiographic methods over the next few years are anticipated with more extensive use of multiplane studies associated with repeated injections of improved contrast materials that produce fewer physiological effects or with substances that adhere to the endocardial surfaces. It is also anticipated that existing methods for automatically obtaining dimensional information from X rays will be continued and improved.

Sandler, H.↗

Demonstration of optical navigation measurements on Mariner 10

An experiment was performed on the Mariner 10 Venus/Mercury mission to assess the performance of the onboard television cameras and ground-based software used in the optical navigation measurement system. The elements of the system, calibration, and distortion are considered. The navigation technique requires detection of stars in the same field of view as the target body. The star detection capability is discussed with reference to required threshold, calibration factors, standard conditions, camera sensitivity, response uniformity, and the effect of image smearing. Tests conducted during the Mariner 10 encounters with Mercury demonstrated that a large bright planet can be imaged simultaneously with faint stars to provide accurate navigation data. Improvements are suggested in the system for the Mariner Jupiter/Saturn 1977 and later missions.

Stanton, R. H.↗