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At least 451 records · Page 25

ICAT: The Interactive Corpus Analysis Tool

The Interactive Corpus Analysis Tool (ICAT) is a Python library for creating dashboards to explore textual datasets and build simple binary classification models to help filter through them and focus on entries of interest. This tool uses a form of interactive machine learning (IML), a paradigm of “machine teaching” (Simard et al., 2017) that sits at the intersection of the fields of human computer interaction (HCI), visual analytics, and machine learning. The intent of ICAT is to allow subject matter experts (SME) with limited to no experience in machine learning to benefit from an iterative human-in-the-loop (HITL) approach to building their own model without needing to understand the details of the underlying algorithm. This interactivity is achieved by allowing the user to create features, label data points, and visually manipulate a representation of the features to manually cluster and investigate data, while a model is trained on the fly based on these actions. ICAT is built on top of the Panel (Holoviz, 2018) library, using a combination of Vega, a custom IPyWidget using D3, and ipyvuetify, and is intended to be used inside of a Jupyter environment.

Martindale, Nathan [Oak Ridge National Laboratory ↗

Racoons ( Procyon Lotor ) Show Higher Trypanosoma Cruzi Detection Rates than Virginia Opossums ( Didelphis Virginiana ) in South Carolina, USA

Chagas disease, a significant public health concern in the Americas, is caused by a protozoan parasite, Trypanosoma cruzi. The life cycle of T. cruzi involves kissing bugs (Triatoma spp.) functioning as vectors and mammalian species serving as hosts. Raccoons (Procyon lotor) and opossums (Didelphis virginiana) have been identified as important reservoir species in the life cycle of T. cruzi, but prevalence in both species in the southeastern US is currently understudied. We quantified T. cruzi prevalence in these two key reservoir species across our study area in South Carolina, US, and identified factors that may influence parasite detection. We collected whole blood from 183 raccoons and 126 opossums and used PCR to detect the presence of T. cruzi. We then used generalized linear models with parasite detection status as a binary response variable and predictor variables of land cover, distance to water, sex, season, and species. Our analysis indicated that raccoons experienced significantly higher parasite detection rates than Virginia opossums, with T. cruzi prevalence found to be 26.5% (95% confidence interval [CI], 20.0–33.8) in raccoons and 10.5% (95% CI, 5.51–17.5) in opossums. Altogether, our results concur with previous studies, in that T. cruzi is established in reservoir host populations in natural areas of the southeastern US.

60 APPLIED LIFE SCIENCES↗

A study of the diffusional behavior of a two-phase metal matrix composite exposed to a high temperature environment

The progress of diffusion-controlled filament-matrix interaction in a metal matrix composite where the filaments and matrix comprise a two-phase binary alloy system was studied by mathematically modeling compositional changes resulting from prolonged elevated temperature exposure. The analysis treats a finite, diffusion-controlled, two-phase moving-interface problem by means of a variable-grid finite-difference technique. The Ni-W system was selected as an example system. Modeling was carried out for the 1000 to 1200 C temperature range for unidirectional composites containing from 6 to 40 volume percent tungsten filaments in a Ni matrix. The results are displayed to show both the change in filament diameter and matrix composition as a function of exposure time. Compositional profiles produced between first and second nearest neighbor filaments were calculated by superposition of finite-difference solutions of the diffusion equations.

Tenney, D. R.↗

Light curve of the optical counterpart of 2A0311-227

Visual and blue light curves are presented for the optical counterpart of the X-ray source 2A0311-227. This system, which is the newest member of the AM Herculis class of binaries, has an orbital period of 81 minutes which also modulates the visual light curve. A Fourier analysis of the data has revealed the presence of a 6-minute oscillation, at least in the visual light curve. Whether or not it is also present in the blue light curve is unclear.

Williams, G.↗

Is 1220 Crocus a precessing, binary asteroid?

Photoelectric data of the asteroid 1220 Crocus over a 13 night period in 1984 revealed the presence of two separate periods. The light curves were indicative of a precessing body, but not one in free precession due to motions induced by a collision. Closer examinations revealed periods of 30.7 and 7.9 hr with amplitudes of 0.87 and 0.15 mag, respectively. An analysis of the source of an external torque which could be causing a forced precession led to the hypothesis that 1220 Crocus has a satellite. Verification of the binary asteroid configuration will depend on more detailed light curves, the possible modulation of the shorter period by the longer, and possible use of the Space Telescope.

Binzel, R. P.↗

Modeling ethanol/water adsorption in all-silica zeolites using the real adsorbed solution theory

A comprehensive set of single-component and binary isotherms were collected for ethanol/water adsorption into the siliceous forms of 185 known zeolites using grand-canonical Monte Carlo simulations. Using these data, a systematic analysis of ideal/real adsorbed-solution theory (IAST/RAST) was conducted and activity coefficients were derived for ethanol/water mixtures adsorbed in different zeolites based on RAST. It was found that activity coefficients of ethanol are close to unity while activity coefficients of water are larger in most zeolites, indicating a positive excess free energy of the mixture. This observation can be attributed to water/ethanol interactions being less favorable than water/water interactions in the single-component adsorption of water at comparable loadings. The deviation from ideal behavior can be highly structure-dependent but no clear correlation with pore diameters was identified. Furthermore, our analysis also demonstrates the following: (1) accurate unary isotherms in the low-loading regime are critical for obtaining physically sensible activity coefficients; (2) the global regression scheme to solve for activity model parameters performs better than fitting activity models to activity coefficients calculated locally at each binary state point; and (3) including the dependence on adsorption potential offers only a minor benefit for describing binary adsorption at the lowest fugacities. Finally, the Margules activity model was found incapable of capturing the non-ideal adsorption behavior over the entire range of fugacities and compositions in all zeolites, but for conditions typical of solution-phase adsorption, RAST predictions using zeolite-specific or even bulk Margules parameters provide an improved description compared to IAST.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

MAXI J1848-015: The first detection of relativistically moving outflows from a globular cluster X-ray binary

Over the past decade, observations of relativistic outflows from outbursting X-ray binaries in the Galactic field have grown significantly. In this work, we present the first detection of moving and decelerating radio-emitting outflows from an X-ray binary in a globular cluster. MAXI J1848−015 is a recently discovered transient X-ray binary in the direction of the globular cluster GLIMPSE-C01. Using observations from the Karl G. Jansky Very Large Array, and a monitoring campaign with the MeerKAT observatory for 500 days, we model the motion of the outflows. This represents some of the most intensive, long-term coverage of relativistically moving X-ray binary outflows to date. We use the proper motions of the outflows from MAXI J1848−015 to constrain the component of the intrinsic jet speed along the line of sight, βint COS θejection, to be =0.19 ± 0.02. Assuming it is located in GLIMPSE-C01, at 3.4 kpc, we determine the intrinsic jet speed, βint = 0.79 ± 0.07, and the inclination angle to the line of sight, θejection = 76° ± 2°. This makes the outflows from MAXI J1848−015 somewhat slower than those seen from many other known X-ray binaries. We also constrain the maximum distance to MAXI J1848−015 to be 4.3 kpc. Finally, we discuss the implications of our findings for the nature of the compact object in this system, finding that a black hole primary is a viable (but as-of-yet unconfirmed) explanation for the observed properties of MAXI J1848−015. If future data and/or analysis provide more conclusive evidence that MAXI J1848−015 indeed hosts a black hole, it would be the first black hole X-ray binary in outburst identified in a Galactic globular cluster.

A. Bahramian↗

Benchmark Dose Analysis of DNA Damage Biomarker Responses Provides Compound Potency and Adverse Outcome Pathway Information for the Topoisomerase II Inhibitor Class of Compounds

Genetic toxicology data have traditionally been utilized for hazard identification to provide a binary call for a compound's risk. Recent advances in the scientific field, especially with the development of high‐throughput methods to quantify DNA damage, have influenced a change of approach in genotoxicity assessment. The in vitro MultiFlow® DNA Damage Assay is one such method which multiplexes γH2AX, p53, phospho‐histone H3 biomarkers into a single‐flow cytometric analysis (Bryce et al., [2016]: Environ Mol Mutagen 57:546–558). This assay was used to study human TK6 cells exposed to each of eight topoisomerase II poisons for 4 and 24 hr. Using PROAST v65.5, the Benchmark Dose approach was applied to the resulting flow cytometric datasets. With “compound” serving as covariate, all eight compounds were combined into a single analysis, per time point and endpoint. The resulting 90% confidence intervals, plotted in Log scale, were considered as the potency rank for the eight compounds. The in vitro MultiFlow data showed a maximum confidence interval span of 1Log, which indicates data of good quality. Patterns observed in the compound potency rank were scrutinized by using the expert rule‐based software program Derek Nexus, developed by Lhasa Limited. Compound sub‐classification and structural alerts were considered contributory to the potencies observed for the topoisomerase II poisons studied herein. The Topo II poison Adverse Outcome Pathway was evaluated with MultiFlow endpoints serving as Key Events. The step‐wise approach described herein can be considered as a foundation for risk assessment of compounds within a specific mode of action of interest. Environ. Mol. Mutagen. 2020. © 2020 Wiley Periodicals, Inc.

Wheeldon, Ryan P.↗

Triply eclipsing triple stars in the northern TESS fields: TICs 193993801, 388459317, and 52041148

In this work we report the discovery and analysis of three new triply eclipsing triple star systems found with the TESS mission during its observations of the northern skies: TICs 193993801, 388459317, and 52041148. We utilized the TESS precision photometry of the binary eclipses and third-body eclipsing events, ground-based archival and follow-up photometric data, eclipse timing variations, archival spectral energy distributions, as well as theoretical evolution tracks in a joint photodynamical analysis to deduce the system masses and orbital parameters of both the inner and outer orbits. In one case (TIC 193993801) we also obtained radial velocity measurements of all three stars. This enabled us to `calibrate' our analysis approach with and without `truth' (i.e., RV) data. We find that the masses are good to 1-3% accuracy with RV data and 3-10% without the use of RV data. In all three systems we were able to find the outer orbital period before doing any detailed analysis by searching for a longer-term periodicity in the ASAS-SN archival photometry data -- just a few thousand ASAS-SN points enabled us to find the outer periods of 49.28 d, 89.86 d, and 177.0 d, respectively. From our full photodynamical analysis we find that all three systems are coplanar to within 1 ∘ −3 ∘ . The outer eccentricities of the three systems are 0.003, 0.10, and 0.62, respectively (i.e., spanning a factor of 200). The masses of the three stars {Aa, Ab, and B} in the three systems are: {1.31, 1.19, 1.34}, {1.82, 1.73, 2.19}, and {1.62, 1.48, 2.74} M ⊙ , respectively.

Tamás Borkovits↗

The Disk Wind in the Rapidly Spinning Stellar-mass Black Hole 4U 1630-472 Observed with NuSTAR

We present an analysis of a short NuSTAR observation of the stellar-mass black hole and low-mass X-ray binary 4U 1630−472. Reflection from the inner accretion disk is clearly detected for the first time in this source, owing to the sensitivity of NuSTAR. With fits to the reflection spectrum, we find evidence for a rapidly spinning black hole, a∗ = 0.985(+0.005/−0.014) (1 sigma statistical errors). However, archival data show that the source has relatively low radio luminosity. Recently claimed relationships between jet power and black hole spin would predict either a lower spin or a higher peak radio luminosity. We also report the clear detection of an absorption feature at 7.03 +/- 0.03 keV, likely signaling a disk wind. If this line arises in dense, moderately ionized gas (log xi = 3.6(+0.2/−0.3) and is dominated by He-like Fe xxv, the wind has a velocity of v/c = 0.043(+0.002/−0.007) (12900(+600/−2100) km s(exp −1)). If the line is instead associated with a more highly ionized gas (log xi = 6.1(+0.7/−0.6)), and is dominated by Fe xxvi, evidence of a blueshift is only marginal, after taking systematic errors into account. Our analysis suggests the ionized wind may be launched within 200-1100 Rg, and may be magnetically driven.

accretion disks↗

Adaptive-Sweep Algorithm for Spacecraft Carrier Acquisition and Tracking: System Analysis and Implementation

This paper presents an adaptive-sweep algorithm that can be used in conjunction with a Phased-Lock Loop to acquire and track the carrier of a Binary Phase-shift Keying signal with residual carrier. This algorithm is useful in proximity links where no Doppler pre-compensation is available at the transmitter, and allows the receiver to acquire the incoming carrier even if the experienced Doppler shift is several orders of magnitude larger than the PLL bandwidth. Other applications for this algorithm include Multiple Uplink per Antenna at the Deep Space Network, and generation of observables (Doppler shift, Doppler rate, range rate) for in-situ navigation purposes. This paper enhances a previously presented adaptive-sweep algorithm and its performance analysis in two fronts. First, the algorithm now uses the direction function to automatically estimate the required frequency jump to achieve PLL lock. This enables a fully adaptive-sweep scheme in which system implementer does not need to manually select thresholds. On the other hand, we study the system performance in the presence of Additive White Gaussian Noise and derive necessary conditions for the system to operate at low signal-to-noise conditions. This allows us to create design rules that specify all parameters of the algorithm given a set of system-level requirements. To test the performance of the proposed algorithm, we implement it in GNU Radio, an open-source Software-Defined Radio that interfaces with several commercial radio peripherals. We use this implementation to demonstrate carrier lock and quantify system performance under different noise conditions. We also test the algorithm using open-loop recordings of two downlinks between the Lunar Reconnaissance Orbiter and the Deep Space Network. We show that even after large frequency jumps (tens of kHz), the proposed system is able to rapidly reacquire the carrier and continue operation.

Divsalar, Dariush↗

Techno-Economic Analysis of Greenfield Geothermal Hybrid Power Plants using a Solar or Natural Gas Steam Topping Cycle

The relatively low generation costs associated with wind, solar photovoltaic (PV), and natural-gas power plants make it challenging for geothermal power plants to produce and sell the power that has the reliability and sustainability characteristics that are greatly needed in U.S. power markets. This is especially true for geothermal resources with low-to-medium temperatures, which results in relatively low-thermal efficiency and generation costs that are higher than those for wind, solar PV, and natural gas. This analysis evaluates solar thermal- and natural-gas combustion waste heat recovery-based topping cycle hybridization of geothermal binary power plants. This approach provides several benefits that may allow geothermal power plants to generate power at more competitive costs. First, the addition of solar thermal energy or natural-gas combustion waste heat input to a geothermal power plant provides additional heat input that can be converted to electrical power. Second, the temperature level of the heat obtained from concentrating solar collectors or natural-gas combustion exhaust is higher than that of geothermal heat, which provides opportunities for improving the efficiency of the conversion of thermal energy to electrical power. Third, the ease with which solar thermal systems integrate with energy storage and the flexibility of natural gas means power generation can occur during peak demand periods. The hybrid cycles are compared to equivalently sized, co-located, independent geothermal, concentrating solar, and/or natural-gas power plants. The hybrid cycle tends to produce slightly more power than the standalone plants combined. However, the hybrid plant Levelized Cost of Energy (LCOE) is slightly higher than the LCOE of the combined standalone power plants for each of the case study locations investigated. Using the steam-topping cycle, organic Rankine cycle (ORC)-bottoming cycle hybrid plant design to combine a solar thermal resource and low- temperature geothermal resource (<120 degrees C) leads to a hybrid plant with a lower LCOE than a standalone geothermal-only system. Thus, hybrid plants may enable the economic development of geothermal resources in locations with low geothermal resource temperatures. However, in areas with higher geothermal resource temperatures (>120 degrees C), the geothermal-only plant has a lower LCOE than the hybrid cycle and thus could be developed without the need for solar heat addition. iv A geothermal-natural-gas reciprocating engine hybrid plant was evaluated for an Elk Hills, California case study location. The Elk Hills case study analysis indicates that when the natural-gas engine operates for more than 12 hours per day the hybrid plant can produce power at an LCOE lower than a standalone geothermal plant, and comparable to that of the standalone natural-gas reciprocating engine, while also reducing the carbon intensity of the power generated relative to the standalone natural-gas engine. This may represent a scenario in which the hybrid plant provides an opportunity for the deployment of a low-temperature geothermal resource that otherwise may have an LCOE too high to develop and operate as a standalone resource, while also reducing the carbon intensity of natural-gas generation sources. A "triple-hybrid" plant that combines natural gas, solar thermal, thermal energy storage, and geothermal was also investigated. A natural-gas combustion turbine (NGCT) is added to the geothermal-solar hybrid such that the hot exhaust gas from the gas turbine provides an alternative source of heat to the steam turbine of the hybrid cycle. Analysis results suggest that the triple-hybrid plant has a significantly higher energy generation and revenue than a standalone NGCT or the original geothermal-solar hybrid. The triple-hybrid design benefits most from using a smaller solar field so that the solar energy can be dispatched at the most valuable times available. The triple-hybrid plant also has a lower LCOE than the standalone NGCT. The triple-hybrid plant was evaluated making simple assumptions about the dispatch profile of the gas cycle, and more nuanced and realistic dispatching schedules should be analyzed in future work.

15 GEOTHERMAL ENERGY↗

FIRM image analysis: A machine learning workflow for quantifying extracellular matrix components from electron microscopy images

The extracellular matrix (ECM) is a complex network of biomolecules that plays an integral role in the structure, processes, and signaling mechanisms of cells and tissues. Identifying and quantifying changes in these matrix components provides insight into the mechanisms behind specific tissue remodeling processes; however, quantifying these changes is challenging due to difficult imaging conditions, complexity of the ECM, and the subtlety of these changes. Current imaging techniques allow us to visualize these critical remodeling events and developments in image analysis have employed a combination of analysis software and machine learning techniques to improve the efficiency and accuracy with which features are measured. Although image analysis has seen much improvement in recent years, there has been no technique developed to address ambiguity in feature edges in electron microscopy images. Presented here is a new machine learning-based workflow for the analysis of microscopy images named FIRM (Feature Identification from Raw Microscopy) that uses a random forest classifier to identify ECM features of interest and generate binary segmentation masks for quantification with ImageJ-FIJI. FIRM performed with an F1 score of 0.794 and greater than 80% accuracy for number and size of features detected. FIRM had similar deviation from the ground truth in the number of identified fibrils, fibril size, and size distributions when compared to human analyses. The results suggest that FIRM performs as well as manual analysis and requires a fraction of the time. This analysis technique is more efficient, eliminates user bias, and can be easily optimized to identify a variety of features, making it useful for any discipline requiring image analysis.

Science & Technology - Other Topics↗

Quantitative investigation of surface structure and interatomic potential with impact-collision ion scattering spectroscopy

Helium ion beam interactions with materials have important implications for magnetic confinement fusion, material modification, and helium ion microscopy. These interactions depend on the precise physics of how helium ions channel into the materials, which can vary greatly based on the local crystalline orientation. Here, we performed a dedicated experiment to investigate helium ion channeling in a well-characterized tungsten single crystal. Time-of-flight impact-collision ion scattering spectroscopy was used to obtain multi-angle maps of the backscattering intensity for 3 keV He + → W(111). We found that the backscattering intensity profile arising from helium ion channeling could be well described by a shadow cone analysis. This analysis revealed that subsurface W atoms as deep as the ninth monolayer contributed to the backscattering intensity profile. Binary collision approximation simulations were performed with MARLOWE to model the experimental maps with sufficient accuracy to allow for quantitative comparisons using reliability factors. These quantitative comparisons were applied to investigate how the W lattice structure and He–W interatomic potential affect the multi-angle maps.

75 CONDENSED MATTER PHYSICS, SUPERCONDUCTIVITY AND↗

Efficient loading of reduced data ensembles produced at ORNL SNS/HFIR neutron time-of-flight facilities

We present algorithmic improvements to the loading operations of certain reduced data ensembles produced from neutron scattering experiments at Oak Ridge National Laboratory (ORNL) facilities. Ensembles from multiple measurements are required to cover a wide range of the phase space of a sample material of interest. They are stored using the standard NeXus schema on individual HDF5 files. This makes it a scalability challenge, as the number of experiments stored increases in a single ensemble file. The present work follows up on our previous efforts on data management algorithms, to address identified input output (I/O) bottlenecks in Mantid, an open-source data analysis framework used across several neutron science facilities around the world. We reuse an in-memory binary-tree metadata index that resembles data access patterns, to provide a scalable search and extraction mechanism. In addition, several memory operations are refactored and optimized for the current common use cases, ranging most frequently from 10 to 180, and up to 360 separate measurement configurations. Results from this work show consistent speed ups in wall-clock time on the Mantid LoadMD routine, ranging from 19% to 23% on average, on ORNL production computing systems. The latter depends on the complexity of the targeted instrument-specific data and the system I/O and compute variability for the shared computational resources available to users of ORNL’s Spallation Neutron Source (SNS) and the High Flux Isotope Reactor (HFIR) instruments. Nevertheless, we continue to highlight the need for more research to address reduction challenges as experimental data volumes, user time and processing costs increase.

Godoy, William↗

Techno-Economic Analysis of Greenfield Geothermal Hybrid Power Plants using a Solar or Natural Gas Steam Topping Cycle

The relatively low generation costs associated with wind, solar PV, and natural gas power plants make it challenging for geothermal power plants to produce and sell the power that has the reliability and sustainability characteristics that are greatly needed in US power markets. This is especially true for geothermal resources with low to medium temperatures, which results in relatively low thermal efficiency and generation costs that are higher than those for wind, solar PV, and natural gas. This analysis evaluates solar thermal- and natural gas combustion waste heat recovery-based topping cycle hybridization of geothermal binary power plants. This approach provides several benefits that may allow geothermal power plants to generate power at more competitive costs. First, the addition of solar thermal energy or natural gas combustion waste heat input to a geothermal power plant provides additional heat input that can be converted to electrical power. Second, the temperature level of the heat obtained from concentrating solar collectors or natural gas combustion exhaust is higher than that of geothermal heat, which provides opportunities for improving the efficiency of the conversion of thermal energy to electrical power. Third, the ease with which solar thermal systems integrate with energy storage and the flexibility of natural gas means power generation can occur during peak demand periods.

14 SOLAR ENERGY↗

Assurance of Reasoning Enabled Systems (ARES)

ARES was in part motivated by the determination of President’s Council of Advisors on Science and Technology (PCAST) on May 13th, 2023 that published a set of inquiries: In an era in which convincing images, audio, and text can be generated with ease on a massive scale, how can we ensure reliable access to verifiable, trustworthy information? How can we be certain that a particular piece of media is genuinely from the claimed source? What technologies, policies, and infrastructure can be developed to detect and counter AI-generated disinformation? In an effort to automatically analyze and patch/optimize code the work in this report describes various neural Machine Learning (ML) analysis engine implementations to assist in situations where source code is deficient or completely lacking to decompile (lift) binary code to ’C’. The goal is to gradually reduce human intervention. To this end, two Large Language Model (LLM) variants (Code LLama 2, LLama 3.1 and Starcoder1, Starcoder 2) where finetuned with ’before/after’ code pairs on the OpenBLAS library. LLama trained on the lowering process, Starcoder trained on the lifting process with National Security Agency’s (NSA) open-source Ghidra decompiler assist. The inferencing test results indicate correctness for only very short sequences for Starcoder 2. Moving forward, the experiments conclude with a set of recommendations of required resources and technologies

97 MATHEMATICS AND COMPUTING↗

IUE observations and interpretation of the symbiotic star RW Hya

The IUE observations of the high excitation symbiotic star RW Hya (gM2 + pec) are discussed. Analysis of the intense UV continuum observed between 1100 A to 2000 A suggests this star is a binary system in which the secondary is identified as a hot subdwarf with T sub eff being approximately 100,000 K. A distance to the system of 1000 pc is deduced. The UV spectrum consists of mainly semiforbidden and allowed transition lines of which the CIV (1548 A, 1550 A) emission lines are particularly strong, and UV continuum at both shorter and longer wavelengths. Strong forbidden lines seem to be absent suggesting the presence of a nebula of high densities. Tidal interaction between the red giant primary and the hot subdwarf is suggested as a likely means to form the observed nebula. RW Hya is suggested as a possible source of soft X-ray emission from material accreting onto the surface of the hot subdwarf. Detection of such emission with HEAO-B would give information if this accretion is taking place via Roche lobe overlow or via capture from a stellar wind emitted by the primary. A general discussion of elemental and ionic abundances in the nebula is also presented.

Kafatos, M.↗