Legacy analysis of dark matter annihilation from the Milky Way dwarf spheroidal galaxies with 14 years of Fermi -LAT data
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McDaniel, Alex (ORCID:0000000284361254)↗
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Results for “Level Of Conservation”
Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.
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Search for squarks and gluinos in final states with jets and missing transverse momentum using 139 fb -1 of $ \sqrt{s} $ = 13 TeV pp collision data with the ATLAS detector
A search for the supersymmetric partners of quarks and gluons (squarks and gluinos) in final states containing jets and missing transverse momentum, but no electrons or muons, is presented. The data used in this search were recorded by the ATLAS experiment in proton-proton collisions at a centre-of-mass energy of $\sqrt{s}$ = 13 TeV during Run 2 of the Large Hadron Collider, corresponding to an integrated luminosity of 139 fb -1 . The results are interpreted in the context of various R -parity-conserving models where squarks and gluinos are produced in pairs or in association and a neutralino is the lightest supersymmetric particle. An exclusion limit at the 95% confidence level on the mass of the gluino is set at 2.30 TeV for a simplified model containing only a gluino and the lightest neutralino, assuming the latter is massless. For a simplified model involving the strong production of mass-degenerate first- and second-generation squarks, squark masses below 1.85 TeV are excluded if the lightest neutralino is massless. These limits extend substantially beyond the region of supersymmetric parameter space excluded previously by similar searches with the ATLAS detector.
72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗
Exploration of mass splitting and muon/tau mixing parameters for an eV-scale sterile neutrino with IceCube
We present the first three-parameter fit to a 3+1 sterile neutrino model using 7.634 years of data from the IceCube Neutrino Observatory on $ν$ μ + $\overline{ν}$ μ charged-current interactions in the energy range 500–9976 GeV. Our analysis is sensitive to the mass-squared splitting between the heaviest and lightest mass state (Δm$^{2}_{41}$), the mixing matrix element connecting muon flavor to the fourth mass state (|U μ4 | 2 ), and the element connecting tau flavor to the fourth mass state (|U $\tau$4 | 2 ). Predicted propagation effects in matter enhance the signature through a resonance as atmospheric neutrinos from the Northern Hemisphere traverse the Earth to the IceCube detector at the South Pole. The remaining sterile neutrino matrix elements are left fixed, with |U e4 | 2 = 0 and δ 14 = 0, as they have a negligible effect, and δ 24 = π is set to give the most conservative limits. The result is consistent with the no-sterile neutrino hypothesis with a probability of 4.3%. Profiling the likelihood of each parameter yields the 90% confidence levels: 2.4eV 2 < Δm$^{2}_{41}$) < 9.6eV 2 , 0.0081< |U μ4 | 2 < 0.10, and |U $\tau$4 | 2 < 0.035, which narrows the allowed parameter-space for |U $\tau$4 | 2 . However, the primary result of this analysis is the first map of the 3+1 parameter space exploring the interdependence of Δm$^{2}_{41}$, |U μ4 | 2 , and |U $\tau$4 | 2 .
72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗
A gene desert required for regulatory control of pleiotropic Shox2 expression and embryonic survival
ABSTRACT The Shox2 homeodomain transcriptional regulator is known for its critical functions during mouse embryogenesis, enabling accurate development of limbs, craniofacial structures, neural populations and the cardiac conduction system. At the genomic level, the Shox2 gene is flanked by an extensive gene desert, a continuous non-coding genomic region spanning over 500 kilobases that contains a multitude of evolutionarily conserved elements with predicted cis -regulatory activities. However, the transcriptional enhancer potential of the vast majority of these elements in combination with the biological necessity of the gene desert have not yet been explored. Using transgenic reporter assays in mouse embryos to validate an extensive set of stringent epigenomic enhancer predictions, we identify several novel gene desert enhancers with distinct tissue-specific activities in Shox2 expressing tissues. 4C-seq chromatin conformation capture further uncovers a repertoire of gene desert enhancers with overlapping activities in the proximal limb, in a compartment essential for Shox2 -mediated stylopod formation. Leveraging CRISPR/Cas9 to delete the gene desert region contained in the Shox2 topologically associated domain (TAD), we demonstrate that this complex cis -regulatory platform is essential for embryonic survival and required for control of region-specific Shox2 expression in multiple developing tissues. While transcription of Shox2 in the embryonic limb is only moderately affected by gene desert loss, Shox2 expression in craniofacial and cardiac domains is nearly abolished. In particular, Shox2 transcripts in the sinus venosus (SV) encompassing the sinoatrial node (SAN) were depleted in embryos lacking the gene desert, likely accounting for the embryonic lethality due to Shox2 -dependency of the SAN pacemaker. Finally, we discover a 1.5kb SV enhancer within the deleted gene desert region, which may act as a genomic module controlling the development of the cardiac conduction system. In summary, our results identify a gene desert indispensable for pleiotropic patterning and highlight the importance of these extensive regulatory landscapes for embryonic development and viability.
Abassah-Oppong, Samuel↗
Enhancing the EVI-X National Framework to Address Emerging Questions on Charging Infrastructure Deployment
As national investments in EV charging infrastructure accelerate, this project advances the state-of-the-art in infrastructure analysis to better inform deployment strategies. It enhances NLR's EVI-X Suite, a set of tools supporting national network planning, local site design, and financial evaluation. These capabilities will position VTO to provide timely analysis to the DOT/DOE Joint Office, and to guide the strategic buildout of the national charging network. EVI-X development is closely coordinated with other VTO-funded efforts to ensure consistent, integrated use of key inputs and outputs, including EV adoption scenarios from TEMPO and infrastructure designs developed through EVs@Scale.
32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗
Machine learning analysis reveals relationship between pomacentrid calls and environmental cues
Sound production rates of fishes can be used as an indicator for coral reef health, providing an opportunity to utilize long-term acoustic recordings to assess environmental change. As acoustic datasets become more common, computational techniques need to be developed to facilitate analysis of the massive data files produced by long-term monitoring. Machine learning techniques demonstrate an advantage in the identification of fish sounds over manual sampling approaches. Here we evaluated the ability of convolutional neural networks to identify and monitor call patterns for pomacentrids (damselfishes) in a tropical reef region of the western Pacific. A stationary hydrophone was deployed for 39 mo (2014-2018) in the National Park of American Samoa to continuously record the local marine acoustic environment. A neural network was trained—achieving 94% identification accuracy of pomacentrids—to demonstrate the applicability of machine learning in fish acoustics and ecology. The distribution of sound production was found to vary on diel and interannual timescales. Additionally, the distribution of sound production was correlated with wind speed, water temperature, tidal amplitude, and sound pressure level. This research has broad implications for state-of-the-art acoustic analysis and promises to be an efficient, scalable asset for ecological research, environmental monitoring, and conservation planning.
59 BASIC BIOLOGICAL SCIENCES↗
Transition from incoherence to coherence in the spontaneous emission of extended systems
Using the results of a previous paper, we study the evolution of a completely excited system of N two-level atoms, distributed in a circular cylinder with dimensions much larger than the wavelength, interacting with all modes of radiation field. We emphasize the distinction between r-conserving (rC) and r-nonconserving (rNC) processes (r is the so-called cooperation number). Considering the number of photons emitted as the discrete independent variable, the evolution is described by a partial difference equation. Numerical solutions of this equation show the transition from rNC dominance at the beginning to rC dominance later. This is also a transition from incoherent to coherent emission of radiation.
Lee, C. T.↗
Predicting ground level impacts of solid rocket motor testing
Beginning in August of 1988 and continuing until the present, NASA at Stennis Space Center, Mississippi has conducted environmental monitoring of selected static test firings of the solid rocket motor used on the Space Shuttle. The purpose of the study was to assess the modeling protocol adapted for use in predicting plume behavior for the Advanced Solid Rocket Motor that is to be tested in Mississippi beginning in the mid-1990's. Both motors use an aluminum/ammonium perchlorate fuel that produces HCl and Al2O3 particulates as the major combustion products of concern. A combination of COMBUS.sr and PRISE.sr subroutines and the INPUFF model are used to predict the centerline stabilization height, the maximum concentration of HCl and Al2O3 at ground level, and distance to maximum concentration. Ground studies were conducted to evaluate the ability of the model to make these predictions. The modeling protocol was found to be conservative in the prediction of plume stabilization height and in the concentrations of the two emission products predicted.
Douglas, Willard L.↗
Analytical investigation of off-design performance of a transonic turbine
The off-design performance and a breakdown of the losses of a transonic turbine were determined by an analytical method that was previously developed for turbines of more conservative design. The analytically obtained performance map is compared with the performance map obtained from an experimental investigation of the turbine. The rotor hub conditions of incidence angle, relative Mach number, and reaction calculated from the analytical results are compared with those calculated from experimental data. The loss breakdown obtained for the transonic turbine did not differ substantially from that previously obtained from a turbine of more conservative design, except that large stator-exit shock losses were predicted for the transonic turbine at low speeds. The trends of the rotor hub incidence angle, relative Mach number, and reaction calculated from the analytical results agreed well with those calculated from the experimental data over the performance range. These trends indicate that, compared with a turbine of more conservative design, the transonic turbine operated over a much smaller range of incidence angle, a much wider range of rotor relative Mach number, and at a considerably lower level of reaction. Good over-all agreement was obtained between the analytically predicted performance and the experimental performance, except at 40-percent design speed, where in the analysis the stator reached limiting loading before the rotor choked. Since this discrepancy resulted from errors in the simplifying assumptions used in the analysis, it is regarded as a limitation in the analytical method as applied to a transonic turbine.
Whitney, Warren J↗
Hyaloscypha finlandica Metabolome Repository
This repository provides the curated data tables, manuscript figure and table exports, dependency records, and workflow scripts supporting an integrated comparative genomics and untargeted LC-MS/MS metabolomics analysis of Hyaloscypha finlandica strain PMI 746, a root-associated dark septate endophyte of poplar. The repository includes genome-mining summaries from antiSMASH, FunBGCeX, BGC-Prophet, and BiG-SCAPE; processed metabolomics inputs; metabolite annotation evidence; statistical outputs; and publication-facing figures and tables. Raw LC-MS/MS spectra, full genome/protein downloads, and large generated tool outputs are referenced through public archive/accession records and are not stored in Git.
59 BASIC BIOLOGICAL SCIENCES↗
Modelica-based system modeling for studying control-related faults in chiller plants and boiler plants serving large office buildings
System modeling is critical when studying operation faults in chiller plants and boiler plants. However, current fault models have difficulties faithfully representing the operation of chiller plants and boiler plants under the effects of those faults, especially the control-related ones. In this study, we present a systematic method to develop high-fidelity models for approximating the behaviors of chiller plants and boiler plants under faulty conditions. Compared to existing ones, the resulting fault models have two advantages: first, they better characterize the dynamic patterns in the system operation. In those models, control architecture and control logic are faithfully implemented. Thus, they can be used to study control-related faults, such as incorrect staging control due to sensor bias and mistuned feedback control. Second, they are readily extensible and can support large-scale investigations to explore different faulty conditions/scenarios. Those models are established in a hierarchical structure while modules in each layer can be redeclared and parameterized at upper layers. In such a case, modifications to the models can be realized through model modifiers and the process can be easily streamlined with scripts. We applied the proposed models in a comprehensive fault impact evaluation of the 13 control-related faults of chiller and boiler plants. In this evaluation, the proposed plant model is coupled with the EnergyPlus thermal load model to study the impact of various faulty scenarios. Based on the evaluation results, we identified the faults that have the most significant impacts on the operation of the chiller and boiler plants, respectively. We also found that the relationship between the impacts of the studied faults and the severity level of the faults are highly non-linear
Huang, Sen↗
Aggregate residential demand flexibility behavior: A novel assessment framework
Residential demand flexibility (DF) could save the U.S. electric grid up to 10 GW of peak demand while supporting increased amounts of renewable generation. However, less than 40% of the estimated DF peak reduction capacity is currently realized, and less than 8% of American households are enrolled. These low participation rates are combined with high rates of "overriding" a DF event and eventual opt-outs among enrolled customers. There is still not a comprehensive understanding of the drivers of DF participation and occupant interaction with DF program signals. We, therefore, present a novel survey processing framework to assess occupant DF-relevant behavior from the American Time Use Survey (ATUS). Using the framework, we summarize both the extensive and intensive behavior of more than 200,000 ATUS respondents (2003-2018 data) and provide insights on the DF-relevant behavior of residential occupants, which is generally overlooked in the literature. Here we use the framework to identify the activity priorities of residential occupants in the United States during different DF-relevant periods (critical peak, peak, and off-peak). These preferred activities capture overlooked routine behaviors that could be barriers to DF participation, if ignored, and might explain the high levels of overrides often exhibited by participants of demand response.
32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗
Rural EVSE Planning and Analysis
The dataset includes detailed anonymized public charging station usage from several rural stations on the ChargePoint and Shell Recharge Solutions (formerly Greenlots) networks situated in and around Athens, Ohio, a rural Appalachian community. Both Level 2 and DC fast charging stations are represented. Historical data in the set date back to 2019; additional data will be uploaded semiannually until the project's completion in 2023. Each charging session recorded includes information on date and time, location, charging station level, session duration, energy delivered, and fuel savings.
32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗
Calculating Average Hot Water Mixes of Residential Plumbing Fittings Using the ANSI 301-2019 Hot Water Draw Model and National Residential Data to Estimate Hot Water Use in Showerheads and Lavatory Faucets
Available studies of hot water use percentages may not necessarily be generalized to a national level given regional differences, varying methodological approaches, and limited sample sizes. While some publicly available usage data, reports, and surveys estimate actual household usage, a lack of water use data specific to end uses make more precise savings calculations difficult. Additionally, most hot water draw models tend to focus on overall household use and may not readily estimate lavatory fixture use. However, reviewing more recent studies and standards enables the U.S. Environmental Protection Agency’s WaterSense program to update its estimates for hot water use and consumers’ corresponding energy and monetary savings to better reflect realworld conditions. This report specifically focuses on improving hot water use and savings estimates of lavatory faucets and showerheads. To estimate the hot water use of lavatory faucets and showerheads, we employed the 2015 Residential Energy Consumption Surveys (RECS) microdata alongside the ANSI 301-2019 Hot Water Draw Model. These estimates account for regional differences in hot water use, including regional cold water inlet temperatures. As a result, the refinements presented in this report are more robust, more recent, and better describe the geographic variation than previous inputs used by the WaterSense program. In addition, the approach described in this paper can be updated over time or tailored to regionally specific needs given available inputs. We conclude that hot water percentages for showers and faucets calculated using publicly available national data are close to the percentages found by regional studies and are consistent with household-level models of water use.
32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗
Comparative genomic and transcriptomic analyses of trans-kingdom pathogen Fusarium solani species complex reveal degrees of compartmentalization
Background: The Fusarium solani species complex (FSSC) comprises fungal pathogens responsible for mortality in a diverse range of animals and plants, but their genome diversity and transcriptome responses in animal pathogenicity remain to be elucidated. We sequenced, assembled and annotated six chromosome-level FSSC clade 3 genomes of aquatic animal and plant host origins. We established a pathosystem and investigated the expression data of F. falciforme and F. keratoplasticum in Chinese softshell turtle (Pelodiscus sinensis) host. Results: Comparative analyses between the FSSC genomes revealed a spectrum of conservation patterns in chromosomes categorised into three compartments: core, fast-core (FC), and lineage-specific (LS). LS chromosomes contribute to variations in genomes size, with up to 42.2% of variations between F. vanettenii strains. Each chromosome compartment varied in structural architectures, with FC and LS chromosomes contain higher proportions of repetitive elements with genes enriched in functions related to pathogenicity and niche expansion. We identified differences in both selection in the coding sequences and DNA methylation levels between genome features and chromosome compartments which suggest a multi-speed evolution that can be traced back to the last common ancestor of Fusarium. We further demonstrated that F. falciforme and F. keratoplasticum are opportunistic pathogens by inoculating P. sinensis eggs and identified differentially expressed genes also associated with plant pathogenicity. These included the most upregulated genes encoding the CFEM (Common in Fungal Extracellular Membrane) domain. Conclusions: The high-quality genome assemblies provided new insights into the evolution of FSSC chromosomes, which also serve as a resource for studies of fungal genome evolution and pathogenesis. This study also establishes an animal model for fungal pathogens of trans-kingdom hosts.
59 BASIC BIOLOGICAL SCIENCES↗
Lower Omo Food Security & Agriculture: Mapping Land Cover Change in Unprotected and Protected Areas in the Lower Omo River Valley, Ethiopia
Ethiopia is home to unique wildlife, biodiversity, and ecosystem services and, like much of the world, is undergoing population growth, development, and land use change. As a result, some biodiverse regions may be at risk of being urbanized, cultivated as agricultural plots, or losing access to water bodies that are essential for maintaining both terrestrial and aquatic life. The DEVELOP team partnered with the Ethiopian Wildlife Conservation Authority to quantify the land cover change between the years 1994, 2010, and 2018. The team utilized Ethiopia’s dry season (January to May) for training point development which was crucial in differentiating the level of greenness between the four land cover classes: water, natural vegetation, cultivated land, and bare ground. The study area covered 62,000 sq.km of the Lower Omo River Valley and includes eight protected areas. We used Landsat 5 Thematic Mapper, Landsat 7 Enhanced Thematic Mapper Plus, Landsat 8 Operational Land Imager, and Shuttle Radar Topography Mission imagery within Google Earth Engine to employ a Random Forest Classifier and identify these four distinct classes. For each of our supervised classifications, overall model accuracy was between 83% (2018) and 89% (1994). Between 1994 and 2018, the Lower Omo Valley experienced an overall increase of 258.57% in water bodies and 291.23% in cultivated areas, while experiencing an 8.91% decrease in natural vegetation and 18.76% bare ground. There was an increase in water bodies and cultivated land and a decrease in natural vegetation and bare ground in unprotected areas and all protected areas. However, protected areas disproportionately experienced an increase in land cover change, including Tama Community Conservation Area which saw a 17,272.33% increase between 1994 and 2018.
Food Security & Agriculture↗
Modeling Impacts of Resilience Architectures for Extreme-Scale Storage Systems
The Scientific Modeling and Simulation of Storage project focused on improving our ability to store information reliably. The project, done jointly at the University of Wisconsin-Madison, Los Alamos National Laboratories, and Sandia National Laboratories, had the main goal of transforming the art of reliable storage system construction into a more precise science. Along those lines, the project developed numerous tools to expose problems in existing systems; these tools, when applied to the state of the art, uncovered numerous flaws in existing approaches, showing that they both are error prone and in some cases contain serious design flaws. The project also led to the creation of new approaches in reliable system construction. One such approach shows how a storage system can adapt its behavior on the fly to deliver higher performance when there are few underlying failures, but then act more conservatively when more failures are occurring to ensure the safe storage of user data. Another approach develops a storage system consistency model which both delivers high performance but high levels of reliability, a significant advance over previous approaches. Overall, the tools developed within the project advanced the science of reliable storage design, and the new approaches that resulted advanced the science of storage system construction.
97 MATHEMATICS AND COMPUTING↗
Overexpression of a Sugarcane BAHD Acyltransferase Alters Hydroxycinnamate Content in Maize Cell Wall
The purification of hydroxycinnamic acids [ p -coumaric acid ( p CA) and ferulic acid (FA)] from grass cell walls requires high-cost processes. Feedstocks with increased levels of one hydroxycinnamate in preference to the other are therefore highly desirable. We identified and conducted expression analysis for nine BAHD acyltransferase ScAts genes from sugarcane. The high conservation of AT10 proteins, together with their similar gene expression patterns, supported a similar role in distinct grasses. Overexpression of ScAT10 in maize resulted in up to 75% increase in total p CA content. Mild hydrolysis and derivatization followed by reductive cleavage (DFRC) analysis showed that p CA increase was restricted to the hemicellulosic portion of the cell wall. Furthermore, total FA content was reduced up to 88%, resulting in a 10-fold increase in the p CA/FA ratio. Thus, we functionally characterized a sugarcane gene involved in p CA content on hemicelluloses and generated a C4 plant that is promising for valorizing p CA production in biorefineries.
59 BASIC BIOLOGICAL SCIENCES↗