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At least 451 records · Page 25

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NASA NTRS1995

A Compact Fiber Optic Eye Diagnostics System

A new fiber optic probe development for determining transport properties of sub-micron particles in fluids experiments in a microgravity environment has been applied to study different parts of the eye. The probe positioned in front of an eye, delivers a low power (approximately a few mu W) light from a laser diode into the eye and guides the light which is back scattered by different components (aqueous humor, lens, and vitreous humor) of the eye through a receiving optical fiber to a photo detector. The probe provides rapid determination of macromolecular diffusivities and their respective size distributions in the eye lens and the gel-like material in the vitreous humor. For a clinical use, the probe is mounted on a standard slit-lamp apparatus simply using Hruby lens holder. The capability of detecting cataracts, both nuclear and cortical, in their early stages of formation, in a non invasive and quantitative fashion, has the potential in patient monitoring and in developing and testing new drugs or diet therapies to 'dissolve' or slow down the cataract formation before the surgery becomes necessary. The ability to detect biochemical and macromolecular changes in the vitreous structure can be very useful in identifying certain diseases of the posterior chamber and their complications, e.g., posterior vitreous detachment and diabetic retinopathy.

Ansari, Rafat R.↗

NASA NTRS1995

Laser-Induced Incandescence Calibration via Gravimetric Sampling

Various beam imaging and/or sheet forming optics delivered light at 1064 nm from a pulsed Nd:YAG laser for use either as a beam of 3 mm radius or as a laser sheet. Imaging measurements were performed with a grated intensified array camera equipped with an ultraviolet f4.5 lens and a 40 mm extension tube. Point measurements were performed using an ultraviolet 250 mm focal length lens to collect and focus the laser induced incandescence (LII) signal into a 1 meter long quartz optical fiber which directed the LII signal to a 1/4 meter monochromator. An aperture preceding the lens restricted the signal collection region to 1 cm along the laser beam at the center of the gravimetric chimney. Signals from the PMT were processed by a boxcar integrator whereas the images were captured digitally using a frame-grabber with 16 MByte of on-board memory. Both 'point' and planar measurements were made with detector gates of 250 ns to minimize possible morphology bias in collection of the LII signal. Additionally, the imaging measurements were performed with broadband spectral collection of the LII signal to maximize the signal and again minimize any potential effects of morphology dependent heating and/or cooling rates. Digital delay generators controlled the firing of he laser, detector gates and data acquisition. Neutral density filters were used for both sets of measurements to maintain signal levels within linear dynamic ranges of the detectors, the range being determined prior to experiments.

VanderWal, R. L.↗

NASA NTRS1996

A tunable crystal diffraction telescope for the International Space Station

A focusing gamma ray telescope is proposed for use onboard the International Space Station. It consists of a tunable crystal diffraction lens which focuses gamma rays onto a small array of germanium detectors located on an extendable boom. While the weight of such an instrument is less than 500 kg, it features an angular resolution of 15 arcsec, an energy resolution of 2 keV and a 3 sigma sensitivity of the order of 10(exp -7) photons/sq cm sec for any individual narrow line at energies of between 200 and 1300 keV. The scientific potential of such a telescope is discussed. The principles of a diffraction lens and a tunable diffraction lens are described.

VonBallmoos, P.↗

NASA NTRS1999

Multi Spectral Imaging System

An optical imaging system provides automatic co-registration of a plurality of multi spectral images of an object which are generated by a plurality of video cameras or other optical detectors. The imaging system includes a modular assembly of beam splitters, lens tubes, camera lenses and wavelength selective filters which facilitate easy reconfiguration and adjustment of the system for various applications. A primary lens assembly generates a real image of an object to be imaged on a reticle which is positioned at a fixed length from a beam splitter assembly. The beam splitter assembly separates a collimated image beam received from the reticle into multiple image beams, each of which is projected onto a corresponding one of a plurality of video cameras. The lens tubes which connect the beam splitter assembly to the cameras are adjustable in length to provide automatic co-registration of the images generated by each camera.

Spiering, Bruce A.↗

NASA NTRS1998

Shear/Defocus Sensitivity of the Mid Infrared Channel (MIR) of the Composite Infrared Spectrometer (CIRS) for the Cassini Mission to Saturn

The Composite Infrared Spectrometer (CIRS) of the Cassini mission to Saturn has two interferometers covering the far infrared and mid infrared wavelength region. The mid infrared wavelength interferometer has a focal plane consisting of a germanium focus lens and HgCdTe array. System level calibration of the CIRS Flight Unit indicated a discrepancy between the expected and actual signal levels. Testing on the CIRS breadboard and Engineering Unit indicated that defocus of the germanium lens could significantly reduce the modulation efficiency of the interferometer in the presence of a moderate degree of wavefront shear. Defocus of the lens in the focal plane was of concern because of the temperature dependence of the index of refraction of germanium and our nominal operation temperature of 170 K. The shear/defocus interaction was extensively investigated and correlated to a newly developed analytical model, It was eventually determined that the CIRS instrument was in focus, had no appreciable wavefront shear and was operating near theoretical limits. The shear/defocus effect is however, of considerable interest, since it has not been described in previous literature on interferometers.

Martino, Anthony J.↗

NASA NTRS1999

Design and Evaluation of a Telecompressor for a Cassegrain

In order to make better use of their telescope's available field for imaging, avid telescope users make use of an optical device known as a telecompressor also known as a Shapley lens or a focal reducer. Rather than widening the field like a Barlow lens by increasing the telescope's focal length a telecompressor does the opposite compressing the field by shortening the telescope's focal length. This allows for shorter exposure times for film and the potential to fit a telescope's entire field onto a CCD camera. A simple telecompressor would consist of a single positive lens. Such a system would be in adequate for astrophotography, which is why telecompressors like many other refractive optical systems are corrected for certain wavelengths of light. Sometimes a telescope can benefit from having the telecompressor designed just for that particular telescope. The director of the observatory at Texas A&M University Kingsville has been contemplating whether or not a custom made telecompressor would hold any benefits. The report discusses the preliminary design and evaluation of an astronomical achromat according to the third order aberration theory. The achromat is then optimized by finite ray-tracing. The achromat's performance as a telecompressor is compared to the performance of a telecompressor designed just for the telescope at TAMUK. The results indicate that the achromat performs about as well as the custom telecompressor. Analysis also presented that the custom telecompressor was optimized for the wrong system could potentially perform much better if it were optimized on the correct system. However in the meantime an ordinary achromat should suit the system well enough for CCD astroimaging.

Carden, Russell↗

NASA NTRS2002

Is There a Cosmological Constant?

The grant contributed to the publication of 18 refereed papers and 5 conference proceedings. The primary uses of the funding have been for page charges, travel for invited talks related to the grant research, and the support of a graduate student, Charles Keeton. The refereed papers address four of the primary goals of the proposal: (1) the statistics of radio lenses as a probe of the cosmological model (#1), (2) the role of spiral galaxies as lenses (#3), (3) the effects of dust on statistics of lenses (#7, #8), and (4) the role of groups and clusters as lenses (#2, #6, #10, #13, #15, #16). Four papers (#4, #5, #11, #12) address general issues of lens models, calibrations, and the relationship between lens galaxies and nearby galaxies. One considered cosmological effects in lensing X-ray sources (#9), and two addressed issues related to the overall power spectrum and theories of gravity (#17, #18). Our theoretical studies combined with the explosion in the number of lenses and the quality of the data obtained for them is greatly increasing our ability to characterize and understand the lens population. We can now firmly conclude both from our study of the statistics of radio lenses and our survey of extinctions in individual lenses that the statistics of optically selected quasars were significantly affected by extinction. However, the limits on the cosmological constant remain at lambda < 0.65 at a 2-sigma confidence level, which is in mild conflict with the results of the Type la supernova surveys. We continue to find that neither spiral galaxies nor groups and clusters contribute significantly to the production of gravitational lenses. The lack of group and cluster lenses is strong evidence for the role of baryonic cooling in increasing the efficiency of galaxies as lenses compared to groups and clusters of higher mass but lower central density. Unfortunately for the ultimate objective of the proposal, improved constraints on the cosmological constant, the next large survey for gravitational lenses did not release its results during the term of the proposal. The research supported the career development. of six graduate students (polar, Fletcher, Herold, Keeton, Deng and Rusin) and two post-docs (Labor and Munoz).

Kochanek, Christopher↗

NASA NTRS1987

Ocular Screening System

Used to detect eye problems in children through analysis of retinal reflexes, the system incorporates image processing techniques. VISISCREEN's photorefractor is basically a 35 millimeter camera with a telephoto lens and an electronic flash. By making a color photograph, the system can test the human eye for refractive error and obstruction in the cornea or lens. Ocular alignment problems are detected by imaging both eyes simultaneously. Electronic flash sends light into the eyes and the light is reflected from the retina back to the camera lens. Photorefractor analyzes the retinal reflexes generated by the subject's response to the flash and produces an image of the subject's eyes in which the pupils are variously colored. The nature of a defect, where such exists, is identifiable by atrained observer's visual examination.

Source record↗

NASA NTRS1983

Close-Range Photogrammetry with Video Cameras

Examples of photogrammetric measurements made with video cameras uncorrected for electronic and optical lens distortions are presented. The measurement and correction of electronic distortions of video cameras using both bilinear and polynomial interpolation are discussed. Examples showing the relative stability of electronic distortions over long periods of time are presented. Having corrected for electronic distortion, the data are further corrected for lens distortion using the plumb line method. Examples of close-range photogrammetric data taken with video cameras corrected for both electronic and optical lens distortion are presented.

Burner, A. W.↗

NASA NTRS1989

Laboratory Calibration and Characterization of Video Cameras

Some techniques for laboratory calibration and characterization of video cameras used with frame grabber boards are presented. A laser-illuminated displaced reticle technique (with camera lens removed) is used to determine the camera/grabber effective horizontal and vertical pixel spacing as well as the angle of non-perpendicularity of the axes. The principal point of autocollimation and point of symmetry are found by illuminating the camera with an unexpanded laser beam, either aligned with the sensor or lens. Lens distortion and the principal distance are determined from images of a calibration plate suitable aligned with the camera. Calibration and characterization results for several video cameras are presented. Differences between these laboratory techniques and test range and plumb line calibration are noted.

Burner, A. W.↗

NASA NTRS1997

Anterior segment sparing to reduce charged particle radiotherapy complications in uveal melanoma

PURPOSE: The purpose of this investigation is to delineate the risk factors in the development of neovascular glaucoma (NVG) after helium-ion irradiation of uveal melanoma patients and to propose treatment technique that may reduce this risk. METHODS AND MATERIALS: 347 uveal melanoma patients were treated with helium-ions using a single-port treatment technique. Using univariate and multivariate statistics, the NVG complication rate was analyzed according to the percent of anterior chamber in the radiation field, tumor size, tumor location, sex, age, dose, and other risk factors. Several University of California San Francisco-Lawrence Berkeley National Laboratory (LBNL) patients in each size category (medium, large, and extralarge) were retrospectively replanned using two ports instead of a single port. By using appropriate polar and azimuthal gaze angles or by treating patients with two ports, the maximum dose to the anterior segment of the eye can often be reduced. Although a larger volume of anterior chamber may receive a lower dose by using two ports than a single port treatment. We hypothesize that this could reduce the level of complications that result from the irradiation of the anterior chamber of the eye. Dose-volume histograms were calculated for the lens, and compared for the single and two-port techniques. RESULTS: NVG developed in 121 (35%) patients. The risk of NVG peaked between 1 and 2.5 years posttreatment. By univariate and multivariate analysis, the percent of lens in the field was strongly correlated with the development of NVG. Other contributing factors were tumor height, history of diabetes, and vitreous hemorrhage. Dose-volume histogram analysis of single-port vs. two-port techniques demonstrate that for some patients in the medium and large category tumor groups, a significant decrease in dose to the structures in the anterior segment of the eye could have been achieved with the use of two ports. CONCLUSION: The development of NVG after helium-ion irradiation is correlated to the amount of lens, anterior chamber in the treatment field, tumor height, proximity to the fovea, history of diabetes, and the development of vitreous hemorrhage. Although the influence of the higher LET deposition of helium-ions is unclear, this study suggests that by reducing the dose to the anterior segment of the eye may reduce the NVG complications. Based on this retrospective analysis of LBNL patients, we have implemented techniques to reduce the amount of the anterior segment receiving a high dose in our new series of patients treated with protons using the cyclotron at the UC Davis Crocker Nuclear Laboratory (CNL).

NASA Discipline Radiation Health↗

NASA NTRS1994

Characterization of the alpha-gamma and alpha-beta complex: evidence for an in vivo functional role of alpha-crystallin as a molecular chaperone

Previous studies have demonstrated that in vitro, alpha-crystallin can protect other lens proteins against extensive denaturation and aggregation. The mechanism of this protection involves preferential binding of the partially denatured protein to a central region of the native alpha-crystallin complex. To test whether a similar phenomenon might occur in vivo, a high molecular weight aggregate (HMWA) fraction was isolated from the aged bovine lens. Negative staining of this preparation revealed the presence of particles of 13-14 nm diameter, characteristic of alpha-crystallin. Immunolocalization of the same particles using antiserum specific for gamma- and beta-crystallins demonstrated preferential binding of these crystallins to the central region of the alpha-crystallin complex. Together, these results provide evidence that in the intact lens, the alpha-crystallins are functionally important molecular chaperones.

NASA Discipline Developmental Biology↗

NASA NTRS2005

Inspection of the Space Shuttle External Tank SOFI Using Near-Field and Focused Millimeter Wave Nondestructive Testing Techniques

The Space Shuttle Columbia's catastrophic failure has been attributed to a piece of external tank SOFI (Spray On Foam Insulation) striking the left wing of the orbiter causing significant damage to some of the reinforced carbon/carbon leading edge wing panels. Subsequently, several nondestructive testing (NDT) techniques have been considered for inspecting the external tank. One such method involves using millimeter waves which have been shown to easily penetrate through the foam and provide high resolution images of its interior structures. This paper presents the results of inspecting three different SOFI covered panels by reflectometers at millimeter wave frequencies, specifically at 100 GHz. Each panel was fitted with various embedded anomalies/inserts representing voids and unbonds of diferent shapes, sizes and locations within each panel. In conjunction with these reJqectome&rs, radiators including a focused lens antenna and a small horn antenna were used. The focused lens antenna provided for a footprint diameter of approximately 1.25 cm (0.5") at 25.4 cm (10") away from the lens surface. The horn antenna was primarily operated in its near-field for obtaining relatively high resolution images. These images were produced using 2 0 scanning mechanisms. Discussions of the difference between the capabilities of these two types of antennas (radiators) for the purpose of inspecting the SOFI as it relates to the produced images are also presented.

Kharkovsky, S.↗

NASA NTRS2005

Promising Results from Three NASA SBIR Solar Array Technology Development Programs

Results from three NASA SBIR solar array technology programs are presented. The programs discussed are: 1) Thin Film Photovoltaic UltraFlex Solar Array; 2) Low Cost/Mass Electrostatically Clean Solar Array (ESCA); and 3) Stretched Lens Array SquareRigger (SLASR). The purpose of the Thin Film UltraFlex (TFUF) Program is to mature and validate the use of advanced flexible thin film photovoltaics blankets as the electrical subsystem element within an UltraFlex solar array structural system. In this program operational prototype flexible array segments, using United Solar amorphous silicon cells, are being manufactured and tested for the flight qualified UltraFlex structure. In addition, large size (e.g. 10 kW GEO) TFUF wing systems are being designed and analyzed. Thermal cycle and electrical test and analysis results from the TFUF program are presented. The purpose of the second program entitled, Low Cost/Mass Electrostatically Clean Solar Array (ESCA) System, is to develop an Electrostatically Clean Solar Array meeting NASA s design requirements and ready this technology for commercialization and use on the NASA MMS and GED missions. The ESCA designs developed use flight proven materials and processes to create a ESCA system that yields low cost, low mass, high reliability, high power density, and is adaptable to any cell type and coverglass thickness. All program objectives, which included developing specifications, creating ESCA concepts, concept analysis and trade studies, producing detailed designs of the most promising ESCA treatments, manufacturing ESCA demonstration panels, and LEO (2,000 cycles) and GEO (1,350 cycles) thermal cycling testing of the down-selected designs were successfully achieved. The purpose of the third program entitled, "High Power Platform for the Stretched Lens Array," is to develop an extremely lightweight, high efficiency, high power, high voltage, and low stowed volume solar array suitable for very high power (multi-kW to MW) applications. These objectives are achieved by combining two cutting edge technologies, the SquareRigger solar array structure and the Stretched Lens Array (SLA). The SLA SquareRigger solar array is termed SLASR. All program objectives, which included developing specifications, creating preliminary designs for a near-term SLASR, detailed structural, mass, power, and sizing analyses, fabrication and power testing of a functional flight-like SLASR solar blanket, were successfully achieved.

Eskenazi, Mike↗

NASA NTRS2005

Various Analyses of Structures and Systems Pertaining to Optical Communications

The Optical Communications Group intends to experiment with a 2 by 2 meter Fresnel lens to determine its likelihood as an alternative to focusing mirrors for optical communications. The lens was delivered in four sections. A support structure was required for the lens in order to hold the four sections in a single flat plane with an adjustable degree angle. In order to use the 200-in. Hale telescope for optical communications purposes, an optical filter membrane must used to pass the communications wavelength while blocking sunlight wavelengths. This filter must withstand wind gusts of up to 50 miles per hour. Stress analysis predicts that the membrane will survive with a safety factor greater than two. The methods used were verified by pressure testing the material. Mechanical and thermodynamic analyses were performed on a simple Golay cell in order to optimize its dimensions for best performance. Flexures are examined as an inexpensive alternative to traditional methods for kinematically constraining a 1.5-meter spherical mirror.

Petersen, Collin W.↗

NASA NTRS1977

Cataract Surgery Tool

The NASA-McGannon cataract surgery tool is a tiny cutter-pump which liquefies and pumps the cataract lens material from the eye. Inserted through a small incision in the cornea, the tool can be used on the hardest cataract lens. The cutter is driven by a turbine which operates at about 200,000 revolutions per minute. Incorporated in the mechanism are two passages for saline solutions, one to maintain constant pressure within the eye, the other for removal of the fragmented lens material and fluids. Three years of effort have produced a design, now being clinically evaluated, with excellent potential for improved cataract surgery. The use of this tool is expected to reduce the patient's hospital stay and recovery period significantly.

Source record↗

NASA NTRS2007

The NASA-Sponsored Study of Cataract in Astronauts (NASCA). Relationship of Exposure to Radiation in Space and the Risk of Cataract Incidence and Progression. Report 1: Recruitment and Methodology

The NASA Study of Cataract in Astronauts (NASCA) is a five-year, multi-centered, investigation of lens opacification in populations of U.S. astronauts, military pilots, and ground-based (nonaviator) comparison participants. For astronauts, the explanatory variable of most interest is radiation exposure during space flight, however to properly evaluate its effect, the secondary effects of age, nutrition, general health, solar ocular exposure, and other confounding variables encountered in non-space flight must also be considered. NASCA contains an initial baseline, cross-sectional objective assessment of the severity of cortical (C), nuclear (N), and posterior subcapsular (PSC) lens opacification, and annual follow-on assessments of severity and progression of these opacities in the population of astronauts and in participants sampled from populations of military pilots and ground-based exposure controls. From these data, NASCA will estimate the degree to which space radiation affects lens opacification for astronauts and how the overall risks of each cataract type for astronauts compared with those of the other exposure control groups after adjusting for differences in age and other explanatory variables.

Chylack, Leo T.↗

NASA NTRS2003

Robust incoherent fiber optic bundle decoder

Apparatus and method for calibrating an incoherent fiber optic bundle for use in transmitting visual or infrared coherent images. The apparatus includes a computer, a computer video monitor, an objective lens adjacent to the input end of the bundle, a second lens adjacent the output end of the bundle, and a CCD camera. The camera transmits video data to the monitor to produce an illuminated fiber optic image. The coordinates for the center of each fiber is found through an imaging process and the output fibers coordinates are related to the input fiber coordinates and processed in the computer to produce a mapping lookup-table (LUT) unique to the specific fiber bundle. Remapping of the LUT due to changes in the lens focus, CCD camera, or the addition of an infrared filter is accomplished by a software utility in the computer.

Roberts, Hilary E.↗