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At least 451 records · Page 25

Color Breakup In Sequentially-Scanned LC Displays

In sequentially-scanned liquid-crystal displays the chromatic components of color pixels are distributed in time. For such displays eye, head, display, and image-object movements can cause the individual color elements to be visible. We analyze conditions (scan designs, types of eye movement) likely to produce color breakup.

Arend, L.↗

Evaluating the Subjective Straight Ahead Before and After Spaceflight

Introduction. This joint European Space Agency/NASA pre- and post-flight study investigates the influence of exposure to microgravity on the subjective straight ahead (SSA) in crewmembers returning from long-duration expeditions to the International Space Station (ISS). The SSA is a measure of the internal representation of body orientation and to be influenced by stimulation of sensory systems involved in postural control. The use of a vibrotactile sensory aid to correct the representation of body tilted relative to gravity is also tested as a countermeasure. This study addresses the sensorimotor research gap to "determine the changes in sensorimotor function over the course of a mission and during recovery after landing." Research Plans. The ISS study will involve eight crewmembers who will participate in three pre-flight sessions (between 120 and 60 days before launch) and then three post-flight sessions on R plus 0/1 day, R plus 4 days, and R plus 8 days. Sixteen control subjects were also tested during three sessions to evaluate the effects of repeated testing and to establish normative values. The experimental protocol includes measurements of gaze and arm movements during the following tasks: (1) Near & Far Fixation: The subject is asked to look at actual targets in the true straight-ahead direction or to imagine these targets in the dark. Targets are located at near distance (arm's length) and far distance (beyond 2 meters). This task is successively performed with the subject's body aligned with the gravitational vertical, and with the subject's body tilted in pitch relative to the gravitational vertical using a tilt chair. Measures are then compared with and without a vibrotactile sensory aid that indicates how far one has tilted relative to the vertical; (2) Eye and Arm Movements: The subject is asked to look and point in the SSA direction in darkness and then make horizontal and vertical eye or arm movements, relative to Earth coordinates (allocentric) and to the subject's head/body reference (egocentric). This task is successively performed with the subject's body aligned with the gravitational vertical, and with subject's body tilted in roll using a tilt chair; (3) Linear Vestibulo-Ocular Reflex: The subject is asked to fixate actual visual targets at near and far distances in the true straight-ahead direction, and to evaluate the distance of these targets. The subject is asked to continue fixating the same imagined targets in darkness while he/she is passively accelerated up and down on a spring-loaded vertical linear accelerator. Results. In the control subject population, the perceived tilt angles, translations, and distances were remarkably close to the actual values. The pointing tasks indicated that the orientation of arm saccades was influenced by both the gravitational vertical and the body idiotropic vector. Repeating the testing did not reveal any significant changes. Preliminary results obtained in three crewmembers before and after flight will also be presented. Applications. A change in an individual's egocentric reference might have negative consequences on evaluating the direction of an approaching object or on the accuracy of reaching movements or locomotion. Consequently, investigating how microgravity affects the target location will have theoretical, operational, and even clinical implications for future space exploration missions. The use of vibrotactile feedback as a sensorimotor countermeasure is applicable to balance therapy applications for patients with vestibular loss and the elderly to mitigate risks due to loss of spatial orientation.

Campbell, D. J.↗

The role of reafference in recalibration of limb movement control and locomotion

The reafference model has frequently been used to explain spatial constancy during eye and head movements. We have found that its basic concepts also form part of the information processing necessary for the control and recalibration of reaching movements. Reaching was studied in a novel force environment--a rotating room that creates centripetal forces of the type that could someday substitute for gravity in space flight, and Coriolis forces which are side effects of rotation. We found that inertial, noncontacting Coriolis forces deviate the path and endpoint of reaching movements, a finding that shows the inadequacy of equilibrium position models of movement control. Repeated movements in the rotating room quickly lead to normal movement patterns and to a failure to perceive the perturbing forces. The first movements made after rotation stops, without Coriolis forces present, show mirror-image deviations and evoke perception of a perturbing force even though none is present. These patterns of sensorimotor control and adaptation can largely be explained on the basis of comparisons of efference copy, reafferent muscle spindle, and cutaneous mechanoreceptor signals. We also describe experiments on human locomotion using an apparatus similar to that which Mittelstaedt used to study the optomotor response of the Eristalis fly. These results show that the reafference principle relates as well to the perception of the forces acting on and exerted by the body during voluntary locomotion.

NASA Discipline Neuroscience↗

Spatial Orientation and Balance Control Changes Induced by Altered Gravito-Inertial Force Vectors

Seventeen healthy and eight vestibular deficient subjects were exposed to an interaural centripetal acceleration of 1 G (resultant 45 deg roll tilt of 1.4 G) on a 0.8 meter radius centrifuge for a period of 90 minutes in the dark. The subjects sat with head fixed upright, except every 4 of 10 minutes when instructed to rotate their head so that their nose and eyes pointed towards a visual point switched on every 3 to 5 seconds at random places (within +/- 30 deg) in the Earth horizontal plane. Motion sickness caused some subjects to limit their head movements during significant portions of the 90 minute period, and led three normal subjects to stop the test earlier. Eye movements, including directed saccades for subjective Earth- and head-referenced planes, were recorded before, during, and immediately after centrifugation using electro-oculography. Postural stability measurements were made before and within ten minutes after centrifugation. In normal subjects, postural sway and multisegment body kinematics were gathered during an eyes-closed head movement cadence (sway-referenced support platform), and in response to translational/rotational platform perturbations. A significant increase in postural sway, segmental motion amplitude and hip frequency was observed after centrifugation. This effect was short-lived, with a recovery time of several postural test trials. There were also asymmetries in the direction of post-centrifugation center of sway and head tilt which depended on the subject's orientation during the centrifugation adaptation period (left ear or right ear out). To delineate the effect of the magnitude of the gravito-inertial vector versus its direction during the adaptive centrifugation period, we tilted eight normal subjects in the roll axis at a 45 deg angle in the dark for 90 minutes without rotational motion. Their postural responses did not change following the period of tilt. Based on verbal reports, normal subjects overestimated roll-tilt during 90 minutes of both tilt and centrifugation stimuli. Subjective estimates of head-horizontal, provided by directed saccades, revealed significant errors after approximately 30 minutes that tended to increase only in the group who underwent centrifugation. Immediately after centrifugation, subjects reported feeling tilted on average 10 degrees in the opposite direction, which was in agreement with the direction of their earth-directed saccades. In vestibular deficient (VD) subjects, postural sway was measured using a sway-referenced or earth-fixed support surface, and with or without a head movement sequence. 'Me protocol was selected for each patient during baseline testing, and corresponded to the most challenging condition in which the patient was able to maintain balance with eyes closed. Bilaterally VD subjects showed no postural decrement after centrifugation, while unilateral VD subjects had varying degrees of decrement. Unilateral VD subjects were tested twice; they underwent centrifugation both with right ear out and left ear out. Their post-centrifuation center of sway shifted at right angles depending on the centrifuge GIF orientation. Bilateral VD subjects bad shifts as well, but no consistent directional trend. VD subjects underestimated roll-tilt during centrifugation, These results suggest that orientation of the gravito-inertial vector and its magnitude arc both used by the central nervous system for calibration of multiple orientation systems. A change in the background gravito-inertial force (otolith input) can rapidly initiate postural and perceptual adaptation in several sensorimotor systems, independent of a structured visual surround.

Kaufman, Galen D.↗

Induction of illusory self-rotation and nystagmus by a rotating sound-field

Subjects seated in darkness often experience illusory self-rotation when exposed to a rotating sound field. Compelling illusions of a self-rotation are generally accompanied by nystagmoid movements of the eyes with the slow phase in the direction opposite that of the experienced self-rotation. These phenomena are related to the functioning of a spatial constancy mechanism by which a stable distinction is normally maintained between movements of self and movements of the environment. The appearance of nystagmus during illusory self-rotating indicates that apparent body orientation can influence oculomotor control.

Lackner, J. R.↗

Sunlight reflections from a solar power satellite on solar mirrors should not harm the eyes

The potential hazard imposed by the reflection of the Sun's image by the solar power satellite (SPS) was examined. In the worst case, where the transmitter is assumed to be a perfect mirror reflecting the Sun's image normal to the atmosphere, the total energy received by the eye would be 3.36 x 10 to the -7th power watts. The eye's optics would blur the 5.6 sec of art image of the transmitter over a disk approximately 6 minutes arc in diameter, reducing the maximum intensity at the retina by 99%. A given cone in the retina would receive even less energy due to the constant random microtremors and microsaccadic movements of the eye muscles which move the retina over an area some 8 minutes of arc in radius, even during steady fixation. Therefore, very conservative estimates show that the reflections from the transmitter could be viewed safety for at least 3.2 hours and that the entire SPS structure could be viewed for a minimum of 1 hour. The solares mirror is briefly considered and is shown to be safe to view for at least 2.4 minutes.

Hyson, M. T.↗

Ocular Counter-Rolling During Centrifugation and Static Tilt

Activation of the gravity sensors in the inner ear-the otoliths-generates reflexes that act to maintain posture and gaze. Ocular counter-rolling (OCR) is an example of such a reflex. When the head is tilted to the side, the eyes rotate around the line of sight in the opposite direction (i.e., counter-rolling). While turning comers, undergoing centrifugation, or making side-to-side tilting head movements, the OCR reflex orients the eyes towards the sum of the accelerations from body movements and gravity. Deconditioning of otolith-mediated reflexes following adaptation to microgravity has been proposed as the basis of many of the postural, locomotor, and gaze control problems experienced by returning astronauts. Evidence suggests that OCR is reduced postflight in about 75% of astronauts tested; but the data are sparse, primarily due to difficulties in recording rotational eye movements. During the Neurolab mission, a short-arm human centrifuge was flown that generated sustained sideways accelerations of 0.5-G and one-G to the head and upper body. This produces OCR; and so for the first time, the responses to sustained centrifugation could be studied without the influence of Earth's gravity on the results. This allowed us to determine the relative importance of sideways and vertical acceleration in the generation of OCR. This also provided the first test of the effects of exposure to artificial gravity in space on postflight otolith-ocular reflexes. There was little difference between the responses to centrifugation in microgravity and on Earth. In both conditions, the induced OCR was roughly proportional to the applied acceleration, with the OCR magnitude during 0.5-G centrifugation approximately 60% of that generated during one-G centrifugation. The overall mean OCR from the four payload crewmembers in response to one-G of sideways acceleration was 5.7 plus or minus 1.1 degree (mean and SD) on Earth. Inflight one-G centrifugation generated 5.7 plus or minus 1.1 degree of OCR, which was a small but significant decrease in OCR magnitude. The postflight OCR was 5.9 plus or minus 1.4 degree, which was not significantly different from preflight values. During both 0.5-G and one-G centrifugation in microgravity, where the head vertical gravitational component was absent, the OCR magnitude was not significantly different from that produced by an equivalent acceleration during static tilt on Earth. This suggests that the larger OCR magnitude observed during centrifugation on Earth was due to the larger body vertical linear acceleration component, which may have activated either the otoliths or the body tilt receptors. In contrast to previous studies, there was no decrease in OCR gain postflight. Our findings raise the possibility that inflight exposure to artificial gravity, in the form of intermittent one-G and 0.5-G centripetal acceleration, may have been a countermeasure to deconditioning of otolith-based orientation reflexes.

Cohen, Bernard↗

Comparison of Active and Passive Head Impulse Testing of the Horizontal Vestibulo-Ocular Reflex: Exploring the Feasibility of Different Approaches for Spaceflight

INTRODUCTION: Astronauts experience a wide variety of sensorimotor disturbances primarily due to microgravity-induced vestibular adaptations during spaceflight. Head Impulse Testing (HIT) will be conducted during the Complement of Integrated Protocols for Human Exploration Research program(CIPHER) Vestibular Health study to examine changes in the horizontal vestibulo-ocular reflex in response to high-velocity head movements to detect changes in peripheral vestibular function [1,2]. However, correct interpretation will require consideration of potential artifacts and the constraints of conducting this test across different phases of the mission. Therefore, the aims of our study were to (1) examine reliability across different test operators, and (2) compare results of active (aHIT) versus passive (pHIT) approaches to evaluate the feasibility of self-administered versus operator-assisted approaches. A comparison of responses with visual viewing of a wall target (default condition) versus vision occluded evaluated the influence of other oculomotor control influence across conditions, and comparison with computer-generated rotator head impulse tests (rHIT) examined the variability associated with the ocular responses independent of the variability in executing the head movements themselves. METHODS: Seventeen non-astronaut volunteers (male n=12, age=22.9 ± 3.0; female n=5, age=27.0 ± 6.0, mean ± std) completed HIT testing using video-oculography (VOG) goggles and a high-torque rotator system. The test order was counterbalanced across conditions: (1) passive head-on-torso (pHIT, default condition for flight study) using two operators (Op1 and Op2), (2) active head-on-torso (aHIT, subject initiated), and (3) passive head and torso using rotary chair (rHIT). Eye and head movement data were processed to obtain gain in each direction. The main outcome measures were average gain and asymmetry [1], as well as the percentage of acceptable trials not excluded due to insufficient head amplitude or recording artifacts. RESULTS: While the pHIT gains were similar with vision (1.032 ± 0.043) and vision occluded (1.029 ± 0.038) conditions, the percentage of acceptable trials was greater with vision (Op1 = 93.0%, Op2 = 93.2%) versus occluded (Op1 = 70.7%, Op2 = 67.6%). The reliability between operators was greater for pHIT gain (Intraclass Correlation, ICC = 0.66, p = 0.001) than for pHIT asymmetry (ICC = 0.57, p = 0.01). The percentage of acceptable trials reduced by ~20% during the self-administered aHITs for both visual conditions and tended to be lower than computer-generated rHITs (76% versus 83%). While the aHIT gains were not significantly different than pHIT gains for vision or vision occluded conditions, these measures were poorly correlated. Both aHIT and pHIT gains were significantly greater than the rHIT gains, presumably due to the reduced velocities from the rotator. The asymmetry measures were poorly correlated across pHIT, aHIT, and rHIT conditions, although none of the subjects had asymmetries greater than 16%. DISCUSSION: Our findings support the feasibility of using the standard pHIT methodology for spaceflight. Similarities between visual conditions reflect that these responses are mediated by the peripheral lateral canals rather than other oculomotor mechanisms. The inter-tester reliability was acceptable despite differences in the tester training. In addition to concerns of non-vestibular mechanisms introduced during self-administered aHITs [2], operator-assisted pHITs resulted in higher percentage of acceptable trials and should result in more efficient and reliable measures during spaceflight.

M R Ehrenburg↗

Dynamics of subjective discomfort in motion sickness as measured with a magnitude estimation method

Eight subjects, wearing left-right vision reversing goggles, executed sequences of controlled active head movements to provoke motion sickness. Head movement sequences were interspaced with periods of eye closure and no head movement to permit partial remission of symptoms between sequences. Subjects reported the level of discomfort experienced by using a magnitude estimation technique derived from Stevens' (1957) ratio scaling method. Using this approach, we demonstrated that the time course of subjective discomfort exhibits a profile, similar in all our subjects, characterized by both fast and slow response components. The potential usefulness of magnitude estimation for research on the dynamic properties of the mechanism generating motion sickness symptoms is discussed.

Bock, O. L.↗

TROPHY: A Topologically Robust Physics-Informed Tracking Framework for Tropical Cyclones

Tropical cyclones (TCs) are among the most destructive weather systems. Realistically and efficiently detecting and tracking TCs are critical for assessing their impacts and risks. In particular, the eye is a signature feature of a mature TC. Therefore, knowing the eyes’ locations and movements is crucial for both operational weather forecasts and climate risk assessments. Recently, a multilevel robustness framework has been introduced to study the critical points of time-varying vector fields. The framework quantifies the robustness (i.e., structural stability) of critical points across varying neighborhoods. By relating the multilevel robustness with critical point tracking, the framework has demonstrated its potential in cyclone tracking. An advantage is that it identifies cyclonic features using only 2D wind vector fields, which is encouraging as most tracking algorithms require multiple dynamic and thermodynamic variables at different altitudes. A disadvantage is that the framework does not scale well computationally for datasets containing a large number of cyclones. Herein this paper introduces a topologically robust physics-informed tracking framework (TROPHY) for TC tracking. The main idea is to integrate physical knowledge of TC to drastically improve the computational efficiency of multilevel robustness framework for large-scale climate datasets. First, during preprocessing, we propose a physics-informed feature selection strategy to filter 90% of critical points that are short-lived and have low stability, thus preserving good candidates for TC tracking. Second, during in-processing, we impose constraints during the multilevel robustness computation to focus only on physics-informed neighborhoods of TCs. We apply TROPHY to 30 years of 2D wind fields from reanalysis data in ERA5 and generate a number of TC tracks. In comparison with the observed tracks, we demonstrate that TROPHY can capture TC characteristics (e.g., frequency, intensity, duration, latitudes with maximum intensity, and genesis) that are comparable to and sometimes even better than a well-validated TC tracking algorithm that requires multiple dynamic and thermodynamic scalar fields.

97 MATHEMATICS AND COMPUTING↗

Operations manual for the patient assist device

Quadriplegic patients and multiple amputee patients are almost totally dependent on nursing personnel for any activities or interests in which they participate. A patient assist device is reported which provides patient control over electrical devices in his environment. The patient operates three switches to acquire control over a desired electrical appliance. The type switches employed are chosen to conform to patient capabilities, even when such capabilities are as limited as eye or head movements. The switch operations are sensed and converted into command signals by the patient assist device to control ten electrical appliances simulataneously and independently.

Schrader, M. A.↗

A Macintosh-Based Scientific Images Video Analysis System

A set of experiments was designed at MIT's Man-Vehicle Laboratory in order to evaluate the effects of zero gravity on the human orientation system. During many of these experiments, the movements of the eyes are recorded on high quality video cassettes. The images must be analyzed off-line to calculate the position of the eyes at every moment in time. To this aim, I have implemented a simple inexpensive computerized system which measures the angle of rotation of the eye from digitized video images. The system is implemented on a desktop Macintosh computer, processes one play-back frame per second and exhibits adequate levels of accuracy and precision. The system uses LabVIEW, a digital output board, and a video input board to control a VCR, digitize video images, analyze them, and provide a user friendly interface for the various phases of the process. The system uses the Concept Vi LabVIEW library (Graftek's Image, Meudon la Foret, France) for image grabbing and displaying as well as translation to and from LabVIEW arrays. Graftek's software layer drives an Image Grabber board from Neotech (Eastleigh, United Kingdom). A Colour Adapter box from Neotech provides adequate video signal synchronization. The system also requires a LabVIEW driven digital output board (MacADIOS II from GW Instruments, Cambridge, MA) controlling a slightly modified VCR remote control used mainly to advance the video tape frame by frame.

Groleau, Nicolas↗

Primate translational vestibuloocular reflexes. IV. Changes after unilateral labyrinthectomy

The effects of unilateral labyrinthectomy on the properties of the translational vestibuloocular reflexes (trVORs) were investigated in rhesus monkeys trained to fixate near targets. Translational motion stimuli consisted of either steady-state lateral and fore-aft sinusoidal oscillations or short-lasting transient displacements. During small-amplitude, steady-state sinusoidal lateral oscillations, a small decrease in the horizontal trVOR sensitivity and its dependence on viewing distance was observed during the first week after labyrinthectomy. These deficits gradually recovered over time. In addition, the vertical response component increased, causing a tilt of the eye velocity vector toward the lesioned side. During large, transient lateral displacements, the deficits were larger and longer lasting. Responses after labyrinthectomy were asymmetric, with eye velocity during movements toward the side of the lesion being more compromised. The most profound effect of the lesions was observed during fore-aft motion. Whereas responses were kinematically appropriate for fixation away from the side of the lesion (e.g., to the left after right labyrinthectomy), horizontal responses were anticompensatory during fixation at targets located ipsilateral to the side of the lesion (e.g., for targets to the right after right labyrinthectomy). This deficit showed little recovery during the 3-mo post-labyrinthectomy testing period. These results suggest that inputs from both labyrinths are important for the proper function of the trVORs, although the details of how bilateral signals are processed and integrated remain unknown.

NASA Discipline Neuroscience↗

Modulation of vergence by off-vertical yaw axis rotation in the monkey: normal characteristics and effects of space flight

Horizontal movements of both eyes were recorded simultaneously using scleral search coils in 2 rhesus monkeys before and after the COSMOS 2229 space-flight of 1992-1993. Another 9 monkeys were tested at comparable time intervals and served as controls. Ocular vergence, defined as the difference in horizontal position between the left and right eyes, was measured during off-vertical yaw axis rotation (OVAR) in darkness. Vergence was modulated sinusoidally as a function of head position with regard to gravity during OVAR. The amplitude of peak-to-peak modulation increased with increments in tilt of the angle of the rotational axis (OVAR tilt angle) that ranged from 15 degrees to 90 degrees. Of the 11 monkeys tested, 1 had no measurable modulation in vergence. In the other 10, the mean amplitude of the peak to peak modulation was 5.5 degrees +/- 1.3 degrees at 90 degrees tilt. Each of these monkeys had maximal vergence when its nose was pointed close to upward (gravity back; mean phase: -0.9 degree +/- 26 degrees). After space flight, the modulation in vergence was reduced by over 50% for the two flight monkeys, but the phase of vergence modulation was not altered. The reduction in vergence modulation was sustained for the 11-day postflight testing period. We conclude that changes in vergence are induced in monkeys by the sinusoidal component of gravity acting along the naso-occipital axis during yaw axis OVAR, and that the modulation of the vergence reflex is significantly less sensitive to linear acceleration after space flight.

Flight Experiment↗

Dynamic Visual Acuity: a Functionally Relevant Research Tool

Coordinated movements between the eyes and head are required to maintain a stable retinal image during head and body motion. The vestibulo-ocular reflex (VOR) plays a significant role in this gaze control system that functions well for most daily activities. However, certain environmental conditions or interruptions in normal VOR function can lead to inadequate ocular compensation, resulting in oscillopsia, or blurred vision. It is therefore possible to use acuity to determine when the environmental conditions, VOR function, or the combination of the two is not conductive for maintaining clear vision. Over several years we have designed and tested several tests of dynamic visual acuity (DVA). Early tests used the difference between standing and walking acuity to assess decrements in the gaze stabilization system after spaceflight. Supporting ground-based studies measured the responses from patients with bilateral vestibular dysfunction and explored the effects of visual target viewing distance and gait cycle events on walking acuity. Results from these studies show that DVA is affected by spaceflight, is degraded in patients with vestibular dysfunction, changes with target distance, and is not consistent across the gait cycle. We have recently expanded our research to include studies in which seated subjects are translated or rotated passively. Preliminary results from this work indicate that gaze stabilization ability may differ between similar active and passive conditions, may change with age, and can be affected by the location of the visual target with respect to the axis of motion. Use of DVA as a diagnostic tool is becoming more popular but the functional nature of the acuity outcome measure also makes it ideal for identifying conditions that could lead to degraded vision. By doing so, steps can be taken to alter the problematic environments to improve the man-machine interface and optimize performance.

Peters, Brian T.↗

Optical flow versus retinal flow as sources of information for flight guidance

The appropriate description is considered of visual information for flight guidance, optical flow vs. retinal flow. Most descriptions in the psychological literature are based on the optical flow. However, human eyes move and this movement complicates the issues at stake, particularly when movement of the observer is involved. The question addressed is whether an observer, whose eyes register only retinal flow, use information in optical flow. It is suggested that the observer cannot and does not reconstruct the image in optical flow; instead they use retinal flow. Retinal array is defined as the projections of a three space onto a point and beyond to a movable, nearly hemispheric sensing device, like the retina. Optical array is defined as the projection of a three space environment to a point within that space. And flow is defined as global motion as a field of vectors, best placed on a spherical projection surface. Specifically, flow is the mapping of the field of changes in position of corresponding points on objects in three space onto a point, where that point has moved in position.

Cutting, James E.↗