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At least 451 records · Page 25

Integrated Medical Model (IMM) Project Verification, Validation, and Credibility (VVandC)

The Integrated Medical Model (IMM) Project supports end user requests by employing the Integrated Medical Evidence Database (iMED) and IMM tools as well as subject matter expertise within the Project. The iMED houses data used by the IMM. The IMM is designed to forecast relative changes for a specified set of crew health and mission success risk metrics by using a probabilistic model based on historical data, cohort data, and subject matter expert opinion. A stochastic approach is taken because deterministic results would not appropriately reflect the uncertainty in the IMM inputs. Once the IMM was conceptualized, a plan was needed to rigorously assess input information, framework and code, and output results of the IMM, and ensure that end user requests and requirements were considered during all stages of model development and implementation, as well as lay the foundation for external review and application. METHODS: In 2008, the Project team developed a comprehensive verification and validation (VV) plan, which specified internal and external review criteria encompassing 1) verification of data and IMM structure to ensure proper implementation of the IMM, 2) several validation techniques to confirm that the simulation capability of the IMM appropriately represents occurrences and consequences of medical conditions during space missions, and 3) credibility processes to develop user confidence in the information derived from the IMM. When the NASA-STD-7009 (7009) [1] was published, the Project team updated their verification, validation, and credibility (VVC) project plan to meet 7009 requirements and include 7009 tools in reporting VVC status of the IMM. Construction of these tools included meeting documentation and evidence requirements sufficient to meet external review success criteria. RESULTS: IMM Project VVC updates are compiled recurrently and include updates to the 7009 Compliance and Credibility matrices. Reporting tools have evolved over the lifetime of the IMM Project to better communicate VVC status. This has included refining original 7009 methodology with augmentation from the HRP NASA-STD-7009 Guidance Document working group and the NASA-HDBK-7009 [2]. End user requests and requirements are being satisfied as evidenced by ISS Program acceptance of IMM risk forecasts, transition to an operational model and simulation tool, and completion of service requests from a broad end user consortium including operations, science and technology planning, and exploration planning. IMM v4.0 is slated for operational release in the FY015 and current VVC assessments illustrate the expected VVC status prior to the completion of customer lead external review efforts. CONCLUSIONS: The VVC approach established by the IMM Project of incorporating Project-specific recommended practices and guidelines for implementing the 7009 requirements is comprehensive and includes the involvement of end users at every stage in IMM evolution. Methods and techniques used to quantify the VVC status of the IMM Project represented a critical communication tool in providing clear and concise suitability assessments to IMM customers. These processes have not only received approval from the local NASA community but have also garnered recognition by other federal agencies seeking to develop similar guidelines in the medical modeling community.

Walton, M.↗

A counter example in linear feature selection theory

The linear feature selection problem in multi-class pattern recognition is described as that of linearly transforming statistical information from n-dimensional (real Euclidean) space into k-dimensional space, while requiring that average interclass divergence in the transformed space decrease as little as possible. Divergence is the expected interclass divergence derived from Hajek two-class divergence; it is known that there always exists a k x n matrix B such that the transformation determined by B maximizes the divergence in k-dimensional space. It is known that, if Q is any k x k invertible matrix, and B is as defined above, then QB again maximizes the divergence in k-space. It is shown that the converse of this result is false: two matrices exist, B sub 1 and B sub 2, each of which maximizes transformed divergence, which are not related in the fashion B sub 2 = QB sub 1 for any k x k matrix Q.

Brown, D. R.↗

On the Possibility of Ill-Conditioned Covariance Matrices in the First-Order Two-Step Estimator

The first-order two-step nonlinear estimator, when applied to a problem of orbital navigation, is found to occasionally produce first step covariance matrices with very low eigenvalues at certain trajectory points. This anomaly is the result of the linear approximation to the first step covariance propagation. The study of this anomaly begins with expressing the propagation of the first and second step covariance matrices in terms of a single matrix. This matrix is shown to have a rank equal to the difference between the number of first step states and the number of second step states. Furthermore, under some simplifying assumptions, it is found that the basis of the column space of this matrix remains fixed once the filter has removed the large initial state error. A test matrix containing the basis of this column space and the partial derivative matrix relating first and second step states is derived. This square test matrix, which has dimensions equal to the number of first step states, numerically drops rank at the same locations that the first step covariance does. It is formulated in terms of a set of constant vectors (the basis) and a matrix which can be computed from a reference trajectory (the partial derivative matrix). A simple example problem involving dynamics which are described by two states and a range measurement illustrate the cause of this anomaly and the application of the aforementioned numerical test in more detail.

Garrison, James L.↗

Feature engineering descriptors, transforms, and machine learning for grain boundaries and variable-sized atom clusters

Abstract Obtaining microscopic structure-property relationships for grain boundaries is challenging due to their complex atomic structures. Recent efforts use machine learning to derive these relationships, but the way the atomic grain boundary structure is represented can have a significant impact on the predictions. Key steps for property prediction common to grain boundaries and other variable-sized atom clustered structures include: (1) describing the atomic structure as a feature matrix, (2) transforming the variable-sized feature matrix to a fixed length common to all structures, and (3) applying a machine learning algorithm to predict properties from the transformed matrices. We examine how these steps and different combinations of engineered features impact the accuracy of grain boundary energy predictions using a database of over 7000 grain boundaries. Additionally, we assess how different engineered features support interpretability, offering insights into the physics of the structure-property relationships.

36 MATERIALS SCIENCE↗

State variable representations in digital control systems with MA-prefiltered measurements

This paper derives three discrete state variable representations for a continuous-time plant driven by a zero-order hold with a combination of instantaneous measurements and measurements prefiltered by a multiinput/multioutput moving average (MA) process. These representations allow the control system engineer to model plants of this type accurately in a form which permits him to use standard techniques to design digital feedback controllers for them. An example is presented which illustrates how to obtain the coefficient matrices in each representation. Guidelines are presented for choosing the best representation to use for any given plant of this type.

Polites, Michael E.↗

Improved Plate and Beam Models for Thermoviscoelastic Constitutive Modeling of Composites

The effective properties of composites are influenced by the time-dependent behavior of polymer matrices very sensitive to changes in temperature. Improved plate and beam models are required to efficiently design, and simulate composite structures when the long-term performance of large anisotropic composite structures is the matter of interest. In this work, mechanics of structure genome (MSG) is used to con-struct linear thermoviscoelastic plate and beam models that can homogenize three-dimensional heterogeneous materials made of constituents with time- and temperature-dependent behavior. The formulation derives the transient strain energy based on integral formulation for thermorheologically simple materials subject to finite temperature changes with the restriction that the strain is small. The reduced time parameter is introduced to relate the time-temperature dependency of the anisotropic material by means of master curves at reference conditions. The new formulation has been implemented in SwiftCompTM, a general-purpose multiscale constitutive modeling code based on MSG. Experimental data and three-dimensional direct numerical simulations of thin-ply high-strain composites (TP-HSC) using a commercial finite element analysis (FEA) package are conducted to verify the accuracy of SwiftCompTM results. The paper also analyzes the relationship between the shift factor of the polymer matrix and the temperature dependencies of the effective beam properties.

Finite element analysis↗

Analysis of urban area land cover using SEASAT Synthetic Aperture Radar data

Digitally processed SEASAT synthetic aperture raar (SAR) imagery of the Denver, Colorado urban area was examined to explore the potential of SAR data for mapping urban land cover and the compatability of SAR derived land cover classes with the United States Geological Survey classification system. The imagery is examined at three different scales to determine the effect of image enlargement on accuracy and level of detail extractable. At each scale the value of employing a simplistic preprocessing smoothing algorithm to improve image interpretation is addressed. A visual interpretation approach and an automated machine/visual approach are employed to evaluate the feasibility of producing a semiautomated land cover classification from SAR data. Confusion matrices of omission and commission errors are employed to define classification accuracies for each interpretation approach and image scale.

Henderson, F. M.↗

Molecular Spectroscopy in Astrophysics: The Case of Polycyclic Aromatic Hydrocarbons

The role of molecular spectroscopy in astrophysics and astrochemistry is discussed in the context of the study of large, complex, carbon-bearing molecules, namely, Polycyclic Aromatic Hydrocarbons or PAHs. These molecular species are now thought to be widespread in the interstellar medium in their neutral and ionized forms. Identifying the carriers responsible for unidentified interstellar spectral bands will allow to derive important information on cosmic elemental abundances as well as information on the physical conditions (density, temperature) reigning in specific interstellar environments. These, in turn, are key elements for a correct understanding of the energetic mechanisms that govern the origin and the evolution of the interstellar medium. A multidisciplinary approach - combining astronomical observations with laboratory simulations and theoretical modeling - is required to address these complex issues. Laboratory spectra of several PAHs, isolated at low temperature in inert gas matrices or seeded in a supersonic jet expansion, are discussed here and compared to the astronomical spectra of reddened, early type, stars. The electronic spectroscopy of PAHs in the ultraviolet, visible, and near-infrared domains is reviewed and an assessment of the potential contribution of PAHs to the interstellar extinction in the ultraviolet and in the visible is discussed.

Salama, Farid↗

Dynamic Stability of Uncertain Laminated Beams Under Subtangential Loads

Because of the inherent complexity of fiber-reinforced laminated composites, it can be challenging to manufacture composite structures according to their exact design specifications, resulting in unwanted material and geometric uncertainties. In this research, we focus on the deterministic and probabilistic stability analysis of laminated structures subject to subtangential loading, a combination of conservative and nonconservative tangential loads, using the dynamic criterion. Thus a shear-deformable laminated beam element, including warping effects, is derived to study the deterministic and probabilistic response of laminated beams. This twenty-one degrees of freedom element can be used for solving both static and dynamic problems. In the first-order shear deformable model used here we have employed a more accurate method to obtain the transverse shear correction factor. The dynamic version of the principle of virtual work for laminated composites is expressed in its nondimensional form and the element tangent stiffness and mass matrices are obtained using analytical integration The stability is studied by giving the structure a small disturbance about an equilibrium configuration, and observing if the resulting response remains small. In order to study the dynamic behavior by including uncertainties into the problem, three models were developed: Exact Monte Carlo Simulation, Sensitivity Based Monte Carlo Simulation, and Probabilistic FEA. These methods were integrated into the developed finite element analysis. Also, perturbation and sensitivity analysis have been used to study nonconservative problems, as well as to study the stability analysis, using the dynamic criterion.

Goyal, Vijay K.↗

Non-intrusive data-driven model reduction for differential–algebraic equations derived from lifting transformations

In this paper we present a non-intrusive data-driven approach for model reduction of nonlinear systems. The approach considers the particular case of nonlinear partial differential equations (PDEs) that form systems of partial differential–algebraic equations (PDAEs) when lifted to polynomial form. Such systems arise, for example, when the governing equations include Arrhenius reaction terms (e.g., in reacting flow models) and thermodynamic terms (e.g., the Helmholtz free energy terms in a phase-field solidification model). Using the known structured form of the lifted algebraic equations, the approach computes the reduced operators for the algebraic equations explicitly, using straightforward linear algebra operations on the basis matrices. The reduced operators for the differential equations are inferred from lifted snapshot data using operator inference, which solves a linear least squares regression problem. The approach is illustrated for the nonlinear model of solidification of a pure material. The lifting transformations reformulate the solidification PDEs as a system of PDAEs that have cubic structure. The operators of the lifted system for this solidification example have affine dependence on key process parameters, permitting us to learn a parametric reduced model with operator inference. Numerical experiments show the effectiveness of the resulting reduced models in capturing key aspects of the solidification dynamics.

42 ENGINEERING↗

On the peridynamic effective force state and multiphase constitutive correspondence principle

This article concerns modeling unsaturated deformable porous media as an equivalent single-phase and single-force state peridynamic material through the effective force state. The balance equations of linear momentum and mass of unsaturated porous media are presented by defining relevant peridynamic states. The energy balance of unsaturated porous media is utilized to derive the effective force state for the solid skeleton that is an energy conjugate to the nonlocal deformation state of the solid, and the suction force state. Through an energy equivalence, a multiphase constitutive correspondence principle is built between classical unsaturated poromechanics and peridynamic unsaturated poromechanics. The multiphase correspondence principle provides a means to incorporate advanced constitutive models in classical unsaturated porous theory directly into unsaturated peridynamic poromechanics. Finally, numerical simulations of localized failure in unsaturated porous media under different matric suctions are presented to demonstrate the feasibility of modeling the mechanical behavior of such three-phase materials as an equivalent single-phase peridynamic material through the effective force state concept.

42 ENGINEERING↗

Entanglement, partial set of measurements, and diagonality of the density matrix in the parton model

To study quantum properties of the hadron wavefunction at small x, we derived the reduced density matrix for soft gluons in the CGC framework. We explicitly showed that the reduced density matrix is not diagonal in the particle number basis. The off-diagonal components are usually ignored in the conventional parton model. We thus defined the density matrix of ignorance by keeping only the part of the reduced density matrix which can be probed in a limited set of experimental measurements. We calculated Von Neumann entropy for both the reduced and ignorance density matrices. The entropy of ignorance is always greater than the entanglement entropy (computed drom the reduced density matrix) of gluons. Finally, we showed that the CGC reduced density matrix for soft gluons can be diagonalized in a thermal basis with Boltzmann weights suggesting thermalization of new quasi-particle states which we dubbed entangolons.

Duan, Haowu↗

Designing linear lattices for round beam in electron storage rings using the solution by linear matrices analysis

For some synchrotron light source beamline applications, a round beam is preferable to a flat one. A conventional method of obtaining round beam in an electron storage ring is to shift its tune close to a linear difference resonance. The linearly coupled beam dynamics is analyzed with perturbation theories, which have certain limitations. In this paper, we adopt the Solution by LInear Matrices (SLIM) analysis to calculate exact beam sizes to design round beam lattices. The SLIM analysis can deal with a generally linearly coupled accelerator lattice. The effects of various coupling sources on beam emittances and sizes can be studied within a self-consistent frame. Both the on- and off-resonance schemes to obtain round beams are explained with examples. The SLIM formalism for two widely used magnet models: combined-function bending magnets, and planar wigglers and undulators, is also derived.

43 PARTICLE ACCELERATORS↗

Stability of distributed parameter systems.

A theorem is derived for the stability of solutions of general linear partial differential equations. A norm of the state space in the form of multiple integrals over the spatial domain is used for the Liapunov functional. Theorems and lemmas are also given for linear time-invariant constant coefficient distributed parameter systems, a class of nonlinear distributed parameter systems and for others with a Lure-type nonlinearity. The theorem conditions are similar to those known for corresponding ordinary differential equations but with operators replacing matrices.

Park, K. E.↗

Clast assemblages of possible deep-seated /77517/ and immiscible-melt /77538/ origins in Apollo 17 breccias

Breccia samples 77517 and 77538 are composed of abundant mineral and lithic clasts set in porous, poorly sintered matrices. Clast assemblages in the two rocks are of contrasting composition and origin. Breccia 77517 has Mg-rich olivine and pyroxene and calcic plagioclase clasts, indicating limited, almost exclusively ANT-suite parentage. A significant feature is the presence of an assemblage (aluminous enstatite, forsterite, anorthite, aluminous spinel) corresponding to spinel cataclasite, a rock type of deep-seated (about 60 km) crustal origin. Breccia 77538 contains Fe-rich pyroxene and rather sodic plagioclase clasts, indicative of predominantly KREEP and/or mare derivation. An important feature is the occurrence of high-K and high-Fe lithic clasts whose compositions resemble those of immiscible-melts produced during late-stage magmatic crystallization, and which probably originated via silicate liquid immiscibility in a KREEP or mare basalt magma. Both rocks contain numerous fine-grained breccia clasts which represent material that has been modified by impact processes at or very near the moon's surface.

Warner, R. D.↗

Fully Associative, Nonisothermal, Potential-Based Unified Viscoplastic Model for Titanium-Based Matrices

A number of titanium matrix composite (TMC) systems are currently being investigated for high-temperature air frame and propulsion system applications. As a result, numerous computational methodologies for predicting both deformation and life for this class of materials are under development. An integral part of these methodologies is an accurate and computationally efficient constitutive model for the metallic matrix constituent. Furthermore, because these systems are designed to operate at elevated temperatures, the required constitutive models must account for both time-dependent and time-independent deformations. To accomplish this, the NASA Lewis Research Center is employing a recently developed, complete, potential-based framework. This framework, which utilizes internal state variables, was put forth for the derivation of reversible and irreversible constitutive equations. The framework, and consequently the resulting constitutive model, is termed complete because the existence of the total (integrated) form of the Gibbs complementary free energy and complementary dissipation potentials are assumed a priori. The specific forms selected here for both the Gibbs and complementary dissipation potentials result in a fully associative, multiaxial, nonisothermal, unified viscoplastic model with nonlinear kinematic hardening. This model constitutes one of many models in the Generalized Viscoplasticity with Potential Structure (GVIPS) class of inelastic constitutive equations.

Source record↗

Root system architecture and environmental flux analysis in mature crops using 3D root mesocosms

Current methods of root sampling typically only obtain small or incomplete sections of root systems and do not capture their true complexity. To facilitate the visualization and analysis of full-sized plant root systems in 3-dimensions, we developed customized mesocosm growth containers. While highly scalable, the design presented here uses an internal volume of 45 ft 3 (1.27 m 3 ), suitable for large crop and bioenergy grass root systems to grow largely unconstrained. Furthermore, they allow for the excavation and preservation of 3-dimensional root system architecture (RSA), and facilitate the collection of time-resolved subterranean environmental data. Sensor arrays monitoring matric potential, temperature and CO 2 levels are buried in a grid formation at various depths to assess environmental fluxes at regular intervals. Methods of 3D data visualization of fluxes were developed to allow for comparison with root system architectural traits. Following harvest, the recovered root system can be digitally reconstructed in 3D through photogrammetry, which is an inexpensive method requiring only an appropriate studio space and a digital camera. We developed a pipeline to extract features from the 3D point clouds, or from derived skeletons that include point cloud voxel number as a proxy for biomass, total root system length, volume, depth, convex hull volume and solidity as a function of depth. Ground-truthing these features with biomass measurements from manually dissected root systems showed a high correlation. We evaluated switchgrass, maize, and sorghum root systems to highlight the capability for species wide comparisons. We focused on two switchgrass ecotypes, upland (VS16) and lowland (WBC3), in identical environments to demonstrate widely different root system architectures that may be indicative of core differences in their rhizoeconomic foraging strategies. Finally, we imposed a strong physiological water stress and manipulated the growth medium to demonstrate whole root system plasticity in response to environmental stimuli. Hence, these new “3D Root Mesocosms” and accompanying computational analysis provides a new paradigm for study of mature crop systems and the environmental fluxes that shape them.

59 BASIC BIOLOGICAL SCIENCES↗

Polarimetric signatures of sea ice. 1: Theoretical model

Physical, structral, and electromagnetic properties and interrelating processes in sea ice are used to develop a composite model for polarimetric backscattering signatures of sea ice. Physical properties of sea ice constituents such as ice, brine, air, and salt are presented in terms of their effects on electromagnetic wave interactions. Sea ice structure and geometry of scatterers are related to wave propagation, attenuation, and scattering. Temperature and salinity, which are determining factors for the thermodynamic phase distribution in sea ice, are consistently used to derive both effective permittivities and polarimetric scattering coefficients. Polarmetric signatures of sea ice depend on crystal sizes and brine volumes, which are affected by ice growth rates. Desalination by brine expulsion, drainage, or other mechanisms modifies wave penetration and scattering. Sea ice signatures are further complicated by surface conditions such as rough interfaces, hummocks, snow cover, brine skim, or slush layer. Based on the same set of geophysical parameters characterizing sea ice, a composite model is developed to calculate effective permittivities and backscattering covariance matrices at microwave frequencies to interpretation of sea ice polarimetric signatures.

Nghiem, S. V.↗