Monitoring and prediction of nervous functions in space.
Monitoring human performance during manned orbital flight for assessment of central nervous system function, noting animal studies during simulated stresses of space flight
FLIGHT SIMULATION↗
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Biomechanical Modeling of the Deadlift Exercise to Improve the Efficacy of Resistive Exercise Microgravity Countermeasures
During long-duration spaceflight missions, astronauts exposure to microgravity without adequate countermeasures can result in losses of muscular strength and endurance, as well as loss of bone mass. As a countermeasure to this challenge, astronauts engage in resistive exercise during spaceflight to maintain their musculoskeletal function. The Hybrid Ultimate Lifting Kit (HULK) has been designed as a prototype exercise device for an exploration-class vehicle; the HULK features a much smaller footprint than previous devices such as the Advanced Resistive Exercise Device (ARED) on the International Space Station (ISS), which makes the HULK suitable for extended spaceflight missions in vehicles with limited volume. As current ISS exercise countermeasure equipment represents an improvement over previous generations of such devices, the ARED is being employed as a benchmark of functional performance. This project involves the development of a biomechanical model of the deadlift exercise, and is novel in that it is the first exercise analyzed in this context to include the upper limbs in the loading path, in contrast to the squat, single-leg squat, and heel raise exercises also being modeled by our team. OpenSim software is employed to develop these biomechanical models of humans performing resistive exercises to assess and improve the new exercise device designs. Analyses include determining differences in joint and muscle forces when using different loading strategies with the device, comparing and contrasting with the ARED benchmark, and determining whether the loading is sufficient to maintain musculoskeletal health. During data collection, the number of repetitions, load, cadence, stance, and grip width are controlled in order to facilitate comparisons between loading configurations. To date, data have been collected for two human subjects performing the deadlift exercise on the HULK device using two different loading conditions. Recorded data include motion capture, electromyography (EMG), ground reaction forces, device load cell data, photos and videos, and anthropometric data. Work is ongoing to perform biomechanical analyses including inverse kinematics and inverse dynamics to compare different versions of the deadlift model in order to determine which provides an appropriate level of detail to study this exercise. This work is supported by the National Space Biomedical Research Institute through NCC 9-58.
physical exercise↗
Challenges to Health During Deep Space Exploration Missions
Long duration missions outside of low Earth orbit will present unique challenges to the maintenance of human health. Stressors with physiologic and psychological impacts are inherent in exploration missions, including reduced gravity, increased radiation, isolation, limited habitable volume, circadian disruptions, and cabin atmospheric changes. Operational stressors such as mission timeline and extravehicular activities must also be considered, and these varied stressors may act in additive or synergistic fashions. Should changes to physiology or behavior manifest as a health condition, the rendering of care in an exploration environment must also be considered. Factors such as the clinical background of the crew, inability to evacuate to Earth in a timely manner, communication delay, and limitations in available medical resources will have an impact on the assessment and treatment of these conditions. The presentations associated with this panel will address these unique challenges from the perspective of several elements of the NASA Human Research Program, including Behavioral Health and Performance, Human Health Countermeasures, Space Radiation, and Exploration Medical Capability.
Watkins, S.↗
Sensor Technologies on Flexible Substrates
NASA Ames has developed sensor technologies on flexible substrates integrated into textiles for personalized environment monitoring and human performance evaluation. Current technologies include chemical sensing for gas leak and event monitoring and biological sensors for human health and performance monitoring. Targeted integration include next generation EVA suits and flexible habitats.
sensors↗
Humans on the International Space Station-How Research, Operations, and International Collaboration are Leading to New Understanding of Human Physiology and Performance in Microgravity
As the International Space Station (ISS) nears completion, and full international utilization is achieved, we are at a scientific crossroads. ISS is the premier location for research aimed at understanding the effects of microgravity on the human body. For applications to future human exploration, it is key for validation, quantification, and mitigation of a wide variety of spaceflight risks to health and human performance. Understanding and mitigating these risks is the focus of NASA s Human Research Program. However, NASA s approach to defining human research objectives is only one of many approaches within the ISS international partnership (including Roscosmos, the European Space Agency, the Canadian Space Agency, and the Japan Aerospace Exploration Agency). Each of these agencies selects and implements their own ISS research, with independent but related objectives for human and life sciences research. Because the science itself is also international and collaborative, investigations that are led by one ISS partner also often include cooperative scientists from around the world. The operation of the ISS generates significant additional data that is not directly linked to specific investigations. Such data comes from medical monitoring of crew members, life support and radiation monitoring, and from the systems that have been implemented to protect the health of the crew (such as exercise hardware). We provide examples of these international synergies in human research on ISS and highlight key early accomplishments that derive from these broad interfaces. Taken as a whole, the combination of diverse research objectives, operational data, international sharing of research resources on ISS, and scientific collaboration provide a robust research approach and capability that no one partner could achieve alone.
Ronbinson, Julie A.↗
Effects of adaptive automation on operator-system performance - 103
Adaptive automation (AA) is the dynamic, real-time change in the degree of automation in response to situational changes. AA systems are being developed in many industries, including for nuclear power plant applications. AA is a promising means of mitigating human performance issues that often arise in highly automated systems. The purpose of this Nuclear Regulatory Commission study was to characterize important AA design features, define the effects of AA on performance, examine the human factors engineering (HFE) guidance available to design and evaluate AA systems, and identify research and development needs. In general, we found that AA improves task performance and situation awareness (SA) while managing workload. Although the research is limited, AA also supports operator recognition of automation failure and recovery. Research on human-system interfaces has identified principles showing promise for supporting SA, including failure detection, and limiting workload. Research further suggests that AA systems are both more effective, and less disruptive and distracting, when they follow rules of interaction similar to those used by human crewmembers. Our general conclusion about the HFE guidance available to designers and reviewers is that it is limited and has not kept pace with automation technology. We discuss several research and development needs that will help support a better understanding of where and how AA should be used and support the development of more comprehensive guidance for AA safety reviews. (authors)
22 GENERAL STUDIES OF NUCLEAR REACTORS↗
Working Time and Fatigue Management
There are physiological limits to human performance, influenced by the internal programming of the sleep homeostat and circadian rhythms. This presentation will provide information about the physiology underlying fatigue, and provide some strategies for better sleep and for managing alertness on the job. This presentation will be provided to personnel at Kennedy Space Center.
fatigue↗
Light Water Reactor Sustainability Program: Use of Time Distributions to Predict Operator Procedure Performance in Dynamic Human Reliability Analysis
The Human Unimodel for Nuclear Technology to Enhance Reliability (HUNTER) framework affords software capable of conducting human reliability analysis (HRA) using a dynamic approach built around operating procedures (OPs) from nuclear power plants (NPPs). Previous HUNTER reports document the development of this software tool, the coupling of HUNTER to the simulator code, the collection of operator performance data by using simulators to calibrate HUNTER models, and linking HUNTER to probabilistic risk assessment (PRA) software. The present report largely addresses two topics. The first is a new function in HUNTER called the HUNTER Procedure Performance Predictor (P3). HUNTER P3 uses HUNTER’s built in Monte Carlo tools featuring human performance variability to identify potential error traps in procedures. The second topic is time distribution analysis to generate time inputs for dynamic HRA. The current analysis was performed to investigate time distributions for task primitives, which are the minimum task unit of analysis used in dynamic HRA modeling. Using the time distribution data, the elapsed time for human actions in an extended loss of AC power (ELAP) scenario is then investigated. Time data and prediction are essential for modeling procedure performance.
99 GENERAL AND MISCELLANEOUS↗
NRC Reviewer Aid for Evaluating the Human Factors Engineering Aspects of Small Modular Reactors
Small modular reactors (SMRs) are a promising approach to meeting future energy needs. Although the electrical output of an individual SMR is relatively small compared to that of typical commercial nuclear plants, they can be grouped to produce as much energy as a utility demands. Furthermore, SMRs can be used for other purposes, such as producing hydrogen and generating process heat. The design characteristics of many SMRs differ from those of current conventional plants and may require a distinct concept of operations (ConOps). The U.S. Nuclear Regulatory Commission (NRC) conducted research to examine the human factors engineering (HFE) and the operational aspects of SMRs. The research identified thirty potential human-performance issues that should be considered in the NRC's reviews of SMR designs and in future research activities. The purpose of this report is to support NRC HFE reviewers of SMR applications by identifying some of the questions that can be asked of applicants whose designs have characteristics identified in the issues. The questions for each issue were identified and organized based on the review elements and guidance contained in Chapter 18 of the Standard Review Plan (NUREG-0800), and the Human Factors Engineering Program Review Model (NUREG-0711).
08 HYDROGEN↗
Shiftwork and Managing Fatigue
There are physiological limits to human performance influenced by the internal programming of the sleep homeostat and circadian rhythms. The presentation will provide information about the physiology underlying fatigue, and provide some strategies for better sleep and for managing alertness on the job. This presentation was originally provided to engineers, technicians and other personnel at Stennis Space Center supporting the accelerated Green Run project (March 2020).
shiftwork↗
Utilizing Gaps and Performance Measures to Inform NASA Environmental Control and Life Support Systems and Human Health and Performance Capability Technology Decisions
Human spaceflight is a complex endeavor requiring multiple capabilities for transportation, crew health, scientific goals, and safe return to Earth. The difference between spaceflight proven capabilities and those needed for future exploration architectures is defined as a capability gap. Capability gaps are not technology specific. Each capability gap may be closed with a wide array of technologies that have unique benefits and challenges. Determining what a capability’s relevant and distinguishing key performance parameters (KPPs) are for a mission is critical. Mass, power, and volume are always constrained and important, but defining these in a way normalized by performance is very important. KPP definition for reliability, dormancy, and integration needs are hard to define but critical. Outside of technical considerations, the programmatic factors of the estimated time to develop the technology and how the technology validation objectives are matured are strong considerations in which technologies should be pursued and how they should leverage earlier mission elements. The Environmental Control and Life Support (ECLSS) and Crew Health and Performance (CHP) capability areas are decomposed to high level gaps. While KPPs should be technology agnostic, they can be used to both compare technologies and measure progress of technology development over time. KPPs help define when the gap is closed, and the core mission objectives can be accomplished. Proposed technology improvements to enhance a capability should balance improved KPPs and against investments in other capabilities that are not yet closed. A selection of gaps, KPPs, and validation objectives and their formulation, current state, and how they inform capability roadmap planning are discussed.
Life Support↗
Trade Space Analyses: Balancing Crew and Mission Design Parameters
In 2020, the Associate Administrator for Human Exploration and Operations and the Agency’s Federated Board requested an assessment to develop a methodology for trade space analysis comparing crew size for Mars missions against mission design parameters. The NASA Engineering and Safety Center (NESC) conducted an assessment to develop a methodology for systematic, repeatable trade space analysis for crew size and developed an initial set of human performance models and a list of candidate crew tasks for NASA’s first mission to Mars. This report contains the results of the NESC assessment.
Humans to Mars↗
Guidance for Deployment of Mobile Technologies for Nuclear Power Plant Field Workers
This report is a guidance document prepared for the benefit of commercial nuclear power plants’ (NPPs) supporting organizations and personnel who are considering or undertaking deployment of mobile technology for the purpose of improving human performance and plant status control (PSC) for field workers in an NPP setting. This document especially is directed at NPP business managers, Electric Power Research Institute, Institute of Nuclear Power Operations, and other non-Information Technology personnel. This information is not intended to replace basic project management practices or reiterate these processes, but is to support decision-making, planning, and preparation of a business case.
46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗
Meta‐Analysis and Regression Modeling of the Impacts of Four Indoor Environmental Quality Metrics on Office Performance
Awareness of how buildings interact with the occupant experience—especially human performance—is becoming more prevalent, as seen by increasing interest and investment in healthy built environments. However, there is a need to synthesize the wide array of existing indoor environmental assessment and performance research in a way that can translate directly to building design and operation. Existing research in this area typically focuses on a single isolated metric and has not focused on making the results utilizable by building practitioners. The aim of this research is to investigate existing office performance literature through meta‐analyses and produce regression models for four indoor environmental quality (IEQ) metrics to support critical decision‐making for building operation and renovation. To reach this aim, a literature review was conducted to identify studies that measure the impact of changing ventilation rate, temperature, horizontal illuminance, and noise level in offices on occupant task performance. This repository of field and laboratory studies was analyzed to visualize the trends between the selected IEQ metrics and task performance. The temperature, ventilation rate, and horizontal illuminance regression models showed clear improvement potential when modifying indoor conditions toward the defined high‐performance range, while the regression model for noise level was inconclusive. The discussion notes the importance of designing holistically for all components of these IEQ categories to utilize the results, for example, good filtration on outdoor air for quantifying ventilation impact and uniform overhead lighting with low contrast for quantifying horizontal illuminance impact. The novelty of this work is in considering multiple facets of the indoor environment under a single, unified analysis schema and producing IEQ‐based performance gains that can directly inform cost‐benefit analyses of building design and renovation.
60 APPLIED LIFE SCIENCES↗
Examining the Relationship between Self-Reported Workload and Resilient Performance in Airline Flight Crews
Workload has long been associated with human performance in aviation. High workload is typically viewed as a system design problem. The aim of this work was to find observable behaviors that guard cognitive resource margins; thus, improve handling of perturbations that arise. Twelve commercial airline flight crews participated in an experiment at NASA Langley Research Center. We explored workload data (NASA Task Load Index) self-reported after completing flight simulation scenarios to see how different individuals, using the same technologies, cope with challenging situations. A trained observer from the same airline as the study participants assessed performance. We differentiated a lower workload crew from a higher workload crew and analyzed their workload and performance. Results indicate that the workload may be a component of pilots’ resilient performance. Initial strategies that reduced workload were classified and these types of behaviors, if implemented correctly, might assist pilots in maintaining functional workload resource margins.
Michael Stewart↗
Examining the Relationship Between Workload and Resilient Performance in Airline Flight Crews
Workload has long been associated with human performance in aviation. High workload is typically viewed as a system design problem. The aim of this work was to find observable behaviors that guard cognitive resource margins; thus, improve handling of perturbations that arise. Twelve commercial airline flight crews participated in an experiment at NASA Langley Research Center. We explored workload data (NASA Task Load Index) self-reported after completing flight simulation scenarios to see how different individuals, using the same technologies, cope with challenging situations. A trained observer from the same airline as the study participants assessed performance. We differentiated a lower workload crew from a higher workload crew and analyzed their workload and performance. Results indicate that the workload may be a component of pilots’ resilient performance. Initial strategies that reduced workload were classified and these types of behaviors, if implemented correctly, might assist pilots in maintaining functional workload resource margins.
Michael Stewart↗
Development of Concentration Ratios and Transfer Factors for Human and Ecological Probabilistic Performance Assessments - 19781
Human and ecological risk assessments utilize concentration ratios and transfer factors to calculate contaminant concentrations in plant and animal tissues in equilibrium with soil or water (concentration ratios) or based on an animal's contaminant intake from various media (transfer factors). These ratios and factors are used to evaluate human dose via food ingestion pathways and to evaluate ecological dose to an organism. In a probabilistic performance assessment, concentration ratio and transfer factor distributions are developed for every element, and these distributions are applied across the spatial and temporal domain of the assessment. As a result, it is necessary to scale the underlying data distributions by applying the central limit theorem to develop appropriate distributions of the mean for the temporal and spatial scale of the model. Herein we discuss the methodologies for identifying and ranking references, and how to develop statistical distributions of concentration ratios and transfer factors for probabilistic performance assessment models. We also discuss factors that could be pertinent to differences when selecting references and developing distributions for human versus ecological risk assessment scenarios. (authors)
12 MANAGEMENT OF RADIOACTIVE AND NON-RADIOACTIVE W↗
Elucidating regulatory processes of intense physical activity by multi-omics analysis
Abstract Background Physiological and biochemical processes across tissues of the body are regulated in response to the high demands of intense physical activity in several occupations, such as firefighting, law enforcement, military, and sports. A better understanding of such processes can ultimately help improve human performance and prevent illnesses in the work environment. Methods To study regulatory processes in intense physical activity simulating real-life conditions, we performed a multi-omics analysis of three biofluids (blood plasma, urine, and saliva) collected from 11 wildland firefighters before and after a 45 min, intense exercise regimen. Omics profiles post- versus pre-exercise were compared by Student’s t -test followed by pathway analysis and comparison between the different omics modalities. Results Our multi-omics analysis identified and quantified 3835 proteins, 730 lipids and 182 metabolites combining the 3 different types of samples. The blood plasma analysis revealed signatures of tissue damage and acute repair response accompanied by enhanced carbon metabolism to meet energy demands. The urine analysis showed a strong, concomitant regulation of 6 out of 8 identified proteins from the renin-angiotensin system supporting increased excretion of catabolites, reabsorption of nutrients and maintenance of fluid balance. In saliva, we observed a decrease in 3 pro-inflammatory cytokines and an increase in 8 antimicrobial peptides. A systematic literature review identified 6 papers that support an altered susceptibility to respiratory infection. Conclusion This study shows simultaneous regulatory signatures in biofluids indicative of homeostatic maintenance during intense physical activity with possible effects on increased infection susceptibility, suggesting that caution against respiratory diseases could benefit workers on highly physical demanding jobs.
59 BASIC BIOLOGICAL SCIENCES↗