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At least 433 records · Page 24

Performance and mood-state parameters during 30-day 6 degrees head-down bed rest with exercise training

The study was designed to determine if performance and mood impairments occur in bed-rested subjects, and if different exercise-training regimens modify or prevent them. Eighteen normal, healthy men were divided on the basis of age, peak oxygen uptake, and maximal isometric knee extension strength into three similar groups: no exercise (NOE), isotonic exercise (ITE), and isokinetic exercise (IKE). A 15-min battery of 10 performance tests and 8 mood and 2 sleep scales were administered daily during ambulatory control, 30 d of absolute bed rest (BR), and 4 d of ambulatory recovery. Performance test proficiency increased (p < 0.05) for all three groups during BR in 7 of 10 tests and there were no consistent significant differences between the three groups. However, during BR, the ITE group was distinguished from the other groups by a decline (p < 0.05) in the activation mood dimension and in two of its constituent scales (motivation and concentration), and by improvement (p < 0.05) in the trouble-falling-asleep and psychological-tension scales. Since few deleterious changes in performance and mood occurred in the three groups and did not exceed baseline ambulatory levels, we conclude that mood and performance did not deteriorate in response to prolonged BR and were not altered by exercise training. However, the decline in activation mood scales in the ITE group may reflect overtraining or excess total workload in this group.

NASA Center ARC↗

Tocopherol in Elder Self-Neglect

Although elder self-neglect is the most common form of elder mistreatment, its pathophysiology is not well understood. Alpha-tocopherol is a lipid soluble antioxidant required for the preservation of cell membranes. Since the association between tocopherol and cognitive impairment in older adults has been described, we explored the possibility of its role in elder self-neglect. OBJECTIVE: (1) To determine whether serum tocopherol levels are associated with elder self-neglect, and (2) to assess the association of serum tocopherol levels and cognitive function in elder self-neglect. METHODS: Serum tocopherol levels were measured in a cohort of 67 self-neglecting elders and 67 matched controls, recruited for the Consortium for Research in Elder Self-neglect of Texas. Pearson s correlation tests were performed to assess bivariate associations between serum tocopherol levels and cognitive function. RESULTS: Mean serum alpha-tocopherol levels were 10.8 +/- 4.7 ug/mL in self-neglect group and 13.0 +/- 4.9 ug/mL in control group (p = 0.006, unpaired student s t-test). None of the participants from either group had alpha-tocopherol level lower than the reference range. Mean serum gamma-tocopherol levels were 2.0 +/- 1.0 ug/mL in self-neglect group and 2.0 +/- 1.1 in control group (p=0.83). Proportion of the elders with gamma-tocopherol level lower than the reference range were 4.5% (3/66) in self-neglect group and 10.4% (7/67) in control group (p=0.32, Fisher s Exact Test). Among the self-neglecting elders, no association was found between serum alpha-tocopherol levels and the Mini-Mental State Examination (MMSE) or the Wolf-Klein Clock Drawing Test (CDT) scores (r =-0.42, p=0.75 for MMSE; r=0.08, p=0.54 for CDT). No association was found between serum gamma-tocopherol levels and the MMSE or the CDT (r=-0.12, p=0.35 for MMSE; r=0.05, p=0.68 for CDT). CONCLUSION: In our sample, neither alpha-tocopherol nor gamma-tocopherol appears to have a role in pathophysiology of elder self-neglect. Nevertheless, significantly lower serum alpha-tocopherol levels in the self neglect group merits further research.

Aung, K.↗

A computerized databank of decompression sickness incidence in altitude chambers

This report describes a hypobaric decompression sickness databank (HDSD) for use with personal computers. The databank consolidates some of the decompression sickness (DCS) information that has accumulated from altitude chamber tests from 1942 to the present. The information was transcribed to a data collection form, screened for accuracy and duplication, and then added to the databank through a computer keyboard. The databank consists of two files; 63 fields contain details of the test conditions in the altitude chamber, the outcome of the test in terms of DCS and venous gas emboli, the physical characteristics of the group of subjects who underwent the test, and the denitrogenation procedures prior to decompression. The HDSD currently contains 378 records that represent 130,012 altitude exposures from 80 sources: scientific journal articles, government and contractor reports, and chapters from books.

Conkin, Johnny↗

TAO Test Vector Evaluation Rev. 1

A group of encounter sets is evaluated as a standard for defining and refining both performance-based and functional-based terminal area MOPS requirements. DAIDALUS-alerting is used together with a variety of sensor configurations: (1) ADS-B level surveillance, (2) TCAS II, (3) ground-based RADAR with three different sets of error parameters.

Adami, Tony↗

Length scale effects of micro- and meso-scale tensile tests of unirradiated and irradiated Zircaloy-4 cladding

Zircaloy-4 is an essential material for cladding structures within fission-based reactors. To explore the changes in properties measured on differing length scales, FIB-machined micro-scale tensile tests were performed on both irradiated and control groups of Zircaloy-4. This was correlated with tensile testing on femtosecond laser-machined meso-scale specimens. Pronounced size effects were found when varying specimen geometry. Increases in tensile geometry size were associated with a reduction in measured yield stress for both irradiated and unirradiated samples. Here, meso-scale testing found strength and strain values similar to that of bulk-scale testing.

36 MATERIALS SCIENCE↗

Life history strategies among soil bacteria—dichotomy for few, continuum for many

Abstract Study of life history strategies may help predict the performance of microorganisms in nature by organizing the complexity of microbial communities into groups of organisms with similar strategies. Here, we tested the extent that one common application of life history theory, the copiotroph-oligotroph framework, could predict the relative population growth rate of bacterial taxa in soils from four different ecosystems. We measured the change of in situ relative growth rate to added glucose and ammonium using both 18O–H2O and 13C quantitative stable isotope probing to test whether bacterial taxa sorted into copiotrophic and oligotrophic groups. We saw considerable overlap in nutrient responses across most bacteria regardless of phyla, with many taxa growing slowly and few taxa that grew quickly. To define plausible life history boundaries based on in situ relative growth rates, we applied Gaussian mixture models to organisms’ joint 18O–13C signatures and found that across experimental replicates, few taxa could consistently be assigned as copiotrophs, despite their potential for fast growth. When life history classifications were assigned based on average relative growth rate at varying taxonomic levels, finer resolutions (e.g., genus level) were significantly more effective in capturing changes in nutrient response than broad taxonomic resolution (e.g., phylum level). Our results demonstrate the difficulty in generalizing bacterial life history strategies to broad lineages, and even to single organisms across a range of soils and experimental conditions. We conclude that there is a continued need for the direct measurement of microbial communities in soil to advance ecologically realistic frameworks.

59 BASIC BIOLOGICAL SCIENCES↗

The Influence of SiC on the Ablation Response of Advanced Refractory Composite Materials

In continuing our studies of advanced refractory composite materials we have recently completed an arc-jet test series of a diverse group of ceramics and ceramic matrix composites. The compositions range from continuous fiber reinforced ceramics to monoliths. Many of these materials contain SiC and one objective of this test series was to identify the influence of SiC oxidation mechanisms on material performance. Hence the arc heater was operated at two conditions; one in which the passive oxidation of SiC would be dominant and the other where the active oxidation of SiC would be dominant. It is shown here that the active oxidation mechanism of SiC does not dominate material performance when it is present at levels equal to or below 20 volume percent.

Bull, Jeffrey D.↗

Novel Problem Solving - The NASA Solution Mechanism Guide

Over the past five years, the Human Health and Performance (HH&P) Directorate at the NASA Johnson Space Center (JSC) has conducted a number of pilot and ongoing projects in collaboration and open innovation. These projects involved the use of novel open innovation competitions that sought solutions from "the crowd", non-traditional problem solvers. The projects expanded to include virtual collaboration centers such as the NASA Human Health and Performance Center (NHHPC) and more recently a collaborative research project between NASA and the National Science Foundation (NSF). These novel problem-solving tools produced effective results and the HH&P wanted to capture the knowledge from these new tools, to teach the results to the directorate, and to implement new project management tools and coursework. The need to capture and teach the results of these novel problem solving tools, the HH&P decided to create a web-based tool to capture best practices and case studies, to teach novice users how to use new problem solving tools and to change project management training/. This web-based tool was developed with a small, multi-disciplinary group and named the Solution Mechanism Guide (SMG). An alpha version was developed that was tested against several sessions of user groups to get feedback on the SMG and determine a future course for development. The feedback was very positive and the HH&P decided to move to the beta-phase of development. To develop the web-based tool, the HH&P utilized the NASA Tournament Lab (NTL) to develop the software with TopCoder under an existing contract. In this way, the HH&P is using one new tool (the NTL and TopCoder) to develop the next generation tool, the SMG. The beta-phase of the SMG is planed for release in the spring of 2014 and results of the beta-phase testing will be available for the IAC meeting in September. The SMG is intended to disrupt the way problem solvers and project managers approach problem solving and to increase the use of novel and more cost and time effective problem solving tools such as open innovation, collaborative research, and virtual collaborative project centers. The HH&P envisions changing project management coursework by including the SMG in the teaching of project management problem solving tools.

Keeton, Kathryn E.↗

Novel platinum group metal-free catalyst ink deposition system for combinatorial polymer electrolyte fuel cell performance evaluation

Here, a new system for rapid and precise fabrication of polymer electrolyte fuel cell (PEFC) membrane-electrode assemblies (MEAs) is introduced to facilitate rapid testing and characterization of platinum group metal-free (PGM-free) catalysts, with minimal waste of materials, using commercial combinatorial hardware and multi-channel potentiostat. The commercial combinatorial system, designed for high-throughput catalyst activity evaluation (i.e., low overpotential and current densities) using gas-diffusion electrodes (GDEs), has been further developed to enable simultaneous evaluation of the high current density performance on air of twenty-five cathodes prepared by coating catalyst-ionomer inks directly onto the membrane using a newly-developed deposition system. A nanopipette or micropipette coupled to a precise peristaltic pump is being used for precise and even catalyst ink deposition onto the membrane in each of twenty-five circular electrodes with areas of <1 cm 2 and in the precise locations required by the commercial combinatorial MEA hardware. The automated ink deposition system is coupled with a custom-designed heated vacuum table mounted on a computer-controlled XY stage to prevent deformation of the membrane and electrode layers during ink deposition onto the membrane. This system was utilized to evaluate the impact of ionomer to catalyst ratio on the hydrogen-air fuel cell performance of the PGM-free catalyst.

25 ENERGY STORAGE↗

Effect of five lubricants on life of AISI 9310 spur gears

Spur-gear surface fatigue tests were conducted with five lubricants using a single lot of consumable-electrode vacuum melted (CVM) AISI 9310 spur gears. The lot of gears was divided into five groups, each of which was tested with a different lubricant. The test lubricants are classified as either a synthetic hydrocarbon, mineral oil, or ester-based lubricant. All five lubricants have imilar viscosity and pressure-viscosity coefficients. A pentaerythritol base stock without sufficient antiwear additives produced a surface fatigue life pproximately 22 percent that of the same base stock with chlorine and phosphorus type additives. The presence of sulfur type antiwear additives in the lubricant did not appear to affect the surface fatigue life of the gears tested. No statistical difference in the 10-percent surface fatigue life was produced with four of the five lubricants.

Townsend, D. P.↗

Traditional plant functional groups explain variation in economic but not size-related traits across the tundra biome

Aim: Plant functional groups are widely used in community ecology and earth system modelling to describe trait variation within and across plant communities. However, this approach rests on the assumption that functional groups explain a large proportion of trait variation among species. We test whether four commonly used plant functional groups represent variation in six ecologically important plant traits. Location: Tundra biome. Time period: Data collected between 1964 and 2016. Major taxa studied: 295 tundra vascular plant species. Methods: We compiled a database of six plant traits (plant height, leaf area, specific leaf area, leaf dry matter content, leaf nitrogen, seed mass) for tundra species. We examined the variation in species-level trait expression explained by four traditional functional groups (evergreen shrubs, deciduous shrubs, graminoids, forbs), and whether variation explained was dependent upon the traits included in analysis. We further compared the explanatory power and species composition of functional groups to alternative classifications generated using post-hoc clustering of species-level traits. Results: Traditional functional groups explained significant differences in trait expression, particularly among traits associated with resource economics, which were consistent across sites and at the biome scale. However, functional groups explained 19% of overall trait variation and poorly represented differences in traits associated with plant size. Post-hoc classification of species did not correspond well with traditional functional groups, and explained twice as much variation in species-level trait expression. Main conclusion: Traditional functional groups only coarsely represent variation in well-measured traits within tundra plant communities, and better explain resource economic traits than size-related traits. We recommend caution when using functional group approaches to predict tundra ecosystem change, or ecosystem functions relating to plant size, such as albedo or carbon storage. We argue that alternative classifications or direct use of specific plant traits could provide new insight for ecological prediction and modelling.

59 BASIC BIOLOGICAL SCIENCES↗

The impacts of training on change deafness and build-up in a flicker task

Performance on auditory change detection tasks can be improved by training. We examined the stimulus specificity of these training effects in behavior and ERPs. A flicker change detection task was employed in which spatialized auditory scenes were alternated until a "change" or "same" response was made. For half of the trials, scenes were identical. The other half contained changes in the spatial locations of objects from scene to scene. On Day 1, participants were either trained on this auditory change detection task (trained group), or trained on a non-auditory change detection task (control group). On Day 2, all participants were tested on the flicker task while EEG was recorded. The trained group showed greater change detection accuracy than the control group. They were less biased to respond "same" and showed full generalization of learning from trained to novel auditory objects. ERPs for "change" compared to "same" trials showed more negative going P1, N1, and P2 amplitudes, as well as a larger P3b amplitude. The P3b amplitude also differed between the trained and control group, with larger amplitudes for the trained group. Analysis of ERPs to scenes viewed prior to a decision revealed build-up of a difference between "change" and "same" trials in N1 and P2. Results demonstrate that training has an impact early in the "same" versus "change" decision-making process, and that the flicker paradigm combined with the ERP method can be used to study the build-up of change detection in auditory scenes.

60 APPLIED LIFE SCIENCES↗

sOPTICS: a modified density-based algorithm for identifying galaxy groups/clusters and brightest cluster galaxies

A direct approach to studying the galaxy–halo connection is to analyse groups and clusters of galaxies that trace the underlying dark matter haloes, emphasizing the importance of identifying galaxy clusters and their associated brightest cluster galaxies (BCGs). In this work, we test and propose a robust density-based clustering algorithm that outperforms the traditional Friends-of-Friends (FoF) algorithm in the currently available galaxy group/cluster catalogues. Our new approach is a modified version of the Ordering Points To Identify the Clustering Structure (OPTICS) algorithm, which accounts for line-of-sight positional uncertainties due to redshift space distortions by incorporating a scaling factor, and is thereby referred to as sOPTICS. When tested on both a galaxy group catalogue based on semi-analytic galaxy formation simulations and observational data, our algorithm demonstrated robustness to outliers and relative insensitivity to hyperparameter choices. In total, we compared the results of eight clustering algorithms. The proposed density-based clustering method, sOPTICS, outperforms FoF in accurately identifying giant galaxy clusters and their associated BCGs in various environments with higher purity and recovery rate, also successfully recovering 115 BCGs out of 118 reliable BCGs from a large galaxy sample. Furthermore, when applied to an independent observational catalogue without extensive re-tuning, sOPTICS maintains high recovery efficiency, confirming its flexibility and effectiveness for large-scale astronomical surveys.

79 ASTRONOMY AND ASTROPHYSICS↗

Biomass yield in a genetically diverse Miscanthus sacchariflorus germplasm panel phenotyped at five locations in Asia, North America, and Europe

Abstract Miscanthus is a high‐yielding bioenergy crop that is broadly adapted to temperate and tropical environments. Commercial cultivation of Miscanthus is predominantly limited to a single sterile triploid clone of Miscanthus × giganteus , a hybrid between Miscanthus sacchariflorus and M. sinensis. To expand the genetic base of M. × giganteus , the substantial diversity within its progenitor species should be used for cultivar improvement and diversification. Here, we phenotyped a diversity panel of 605 M. sacchariflorus from six previously described genetic groups and 27 M. × giganteus genotypes for dry biomass yield and 16 yield‐component traits, in field trials grown over 3 years at one subtropical location (Zhuji, China) and four temperate locations (Foulum, Denmark; Sapporo, Japan; Urbana, Illinois; and Chuncheon, South Korea). There was considerable diversity in yield and yield‐component traits among and within genetic groups of M. sacchariflorus , and across the five locations. Biomass yield of M. sacchariflorus ranged from 0.003 to 34.0 Mg ha −1 in year 3. Variation among the genetic groups was typically greater than within, so selection of genetic group should be an important first step for breeding with M. sacchariflorus . The Yangtze 2x genetic group (=ssp. lutarioriparius ) of M. sacchariflorus had the tallest and thickest culms at all locations tested. Notably, the Yangtze 2x genetic group's exceptional culm length and yield potential were driven primarily by a large number of nodes (>29 nodes culm −1 average over all locations), which was consistent with the especially late flowering of this group. The S Japan 4x, the N China/Korea/Russia 4x, and the N China 2x genetic groups were also promising genetic resources for biomass yield, culm length, and culm thickness, especially for temperate environments. Culm length was the best indicator of yield potential in M. sacchariflorus . These results will inform breeders' selection of M. sacchariflorus genotypes for population improvement and adaptation to target production environments.

59 BASIC BIOLOGICAL SCIENCES↗

Integration of CFD and Wind-Tunnel Testing at NASA

The debate over when wind-tunnel testing will be replaced by Computational Fluid Dynamics (CFD) comes and goes. More recently, however, the debate has subsided with a more collaborative spirit between practitioners of these two disciplines. Combining these complementary disciplines has led to significant improvements in both as well as better understanding of aero- and fluid dynamics. Also, as CFD codes become more accurate, the need for comparisons with experimental data has increased. New measurement techniques, pressure-sensitive paint and off-body velocity measurements for example, have provided detailed, high-quality data for the comparisons. In-tunnel CFD simulations are also providing more direct comparisons between predicted and measured flows. Given this newenvironment, a concerted effort is now underway to facilitate in-tunnel CFD for the 12 major wind tunnels operated by NASA.The Aerosciences Evaluation and Test Capabilities Portfolio (AETC) manages the major aerodynamic ground-testing facilities within NASA. This group is responsible for the operation, maintenance, and improvement of the wind-tunnel facilities and their capabilities. AETC has recently added a project to integrate CFD and wind-tunnel testing to better support customers of the NASA wind tunnels and to better understand the flow in the wind tunnels themselves. Being able to perform CFD simulations of wind-tunnel models in the wind tunnel environment providesthe cleanest way to assess the accuracy of the simulations relative to test data. AETC plans to provide accurate geometry and guidance to wind-tunnel customers who request it, to facilitate in-tunnel simulations. How this effort got started will be presented along with the status and plans for the project.

CFD↗

LANDSAT Range Resource Information System

A series of test products were developed from LANDSAT data sets for North Central Texas that paralleled the needs of ranchers, technical personnel, and the media. The products and evaluation questionnaires were mailed to approximately 150 ranchers who had reported an interest in evaluating the information systems. In addition to the rancher group, fourteen media people and a thirty-three member group in the agri business/technical community was also chosen to receive test products. The group responses are analyzed. Examples of the test products and associated questionnaires are included.

Boyd, W. E.↗

Future Liver Remnant Indocyanine Green Plasma Clearance Rate as a Predictor of Post-hepatectomy Liver Failure After Portal Vein Embolization

PurposeTo evaluate the utility of future liver remnant plasma clearance rate of indocyanine green (ICGK-F) for predicting post-hepatectomy liver failure (PHLF) compared with percentage future liver remnant volume-to-total liver volume ratio (%FLR) after portal vein embolization (PVE).Materials and MethodsPVE procedures in 20 patients (15 patients underwent PVE with absolute ethanol; 5 patients with gelatin particles) from 2010 to 2017 were analyzed. %FLR = future liver remnant volume (ml)/[total liver volume (ml) − tumor volume (ml)] × 100; ICGK-F = plasma clearance rate of indocyanine green (ICGK) × %FLR/100 were calculated before and after PVE. PHLF was categorized according to the criteria of the International Study Group of Liver Surgery. For predicting PHLF, we compared the ICGK-F and %FLR after PVE between the grade A PHLF group and the non-grade A PHLF (grades B and C) group.ResultsAll PVE procedures were successful. While the ICGK-F of the grade A PHLF group (median 0.073, n = 16) was about twice that of the non-grade A PHLF group (median 0.043, n = 4), showing a significant difference (Mann–Whitney U test: P = 0.002), there was no significant difference in %FLR between the grade A PHLF group and the non-grade A PHLF group (Mann–Whitney U test: P = 0.335).ConclusionICGK-F was significantly higher in the grade A PHLF group than in the non-grade A PHLF group (grades B and C), and ICGK-F was more useful for predicting PHLF than %FLR.

62 RADIOLOGY AND NUCLEAR MEDICINE↗

Reexamination of the Edge Crack Torsion Test for Determining the Mode III Delamination Toughness of Laminated Composites

The edge crack torsion (ECT) test is reexamined to address two primary concerns with this method. The first of these relates to inconsistencies in the data reduction procedure that was originally proposed and is most commonly used to compute the mode III interlaminar fracture toughness, G(sub IIIc), from the experimental data. The second relates to the observation that plies neighboring the preimplanted insert in the standard ECT layup are unable to contain initiation and growth of intralaminar cracks, and that growth of these cracks contributes to errors in the apparent values of G(sub IIIc). To address these issues, an alternative data reduction technique, which uses a polynomial expression to represent the ECT specimen’s compliance versus crack length relation, is proposed. The accuracy and potential drawbacks of this expression are investigated using FE simulations. Next, seven groups of ECT specimens are fabricated and tested. Each of these groups contains specimens with preimplanted inserts that are bounded by plies at different +q and -q orientations. The seven groups consist of values of q that vary from 0° to 90° in 15° increments. Tests on these specimens show that intralaminar cracking occurs in specimens from all batches except those for which q equals 15° or 30°. However, values of G(sub IIIc) measured using specimens with these two ply orientations were not equal and, for q = 30°, the values of G(sub IIIc) that were obtained were not completely independent of initial starter crack length. Potential issues accounting for these observations and other challenges associated with measuring G(sub IIIc) using the ECT test are discussed.

Polymer matrix composites↗