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At least 415 records · Page 23

Hindlimb Suspension as a Model to Study Ophthalmic Complications in Microgravity Status Report: Optimization of Rat Retina Flat Mounts Staining to Study Vascular Remodeling

Preliminary data from a prior tissue‐sharing experiment has suggested that early growth response protein‐1 (Egr1), a transcription factor involved in various stress responses in the vasculature, is induced in the rat retina after 14 days of hindlimb suspension (HS) and may be evidence that mechanical stress is occurring secondary to the cephalad fluid shift. This mechanical stress could cause changes in oxygenation of the retina, and the subsequent ischemia‐ or inflammation‐driven hypoxia may lead to microvascular remodeling. This microvascular remodeling process can be studied using image analysis of retinal vessels and can be then be quantified by the VESsel GENeration Analysis (VESGEN) software, a computational tool that quantifies remodeling patterns of branching vascular trees and capillary or vasculogenic networks. Our project investigates whether rodent HS is a valid model to study the effects of simulated‐weightlessness on ocular structures and their relationship with intracranial pressure (ICP). One of the hypotheses to be tested is that HS‐induced cephalad fluid shift is accompanied by vascular engorgement that produces changes in retinal oxygenation, leading to oxidative stress, hypoxia, microvascular remodeling, and cellular degeneration. We have optimized the procedure to obtain flat mounts of rat retina, staining of the endothelial lining in vasculature and acquisition of high quality images suitable for VESGEN analysis. Briefly, eyes were fixed in 4% paraformaldehyde for 24 hours and retinas were detached and then mounted flat on microscope slides. The microvascular staining was done with endothelial cell‐specific isolectin binding, coupled to Alexa‐488 fluorophore. Image acquisition at low magnification and high resolution was performed using a new Leica SP8 confocal microscope in a tile pattern across the X,Y plane and multiple sections along the Z‐axis. This new confocal microscope has the added capability of dye separation using the Linear Unmixing method and allows us to remove the autofluorescence originating from the photoreceptor layer. In summary, we have an improved method for studying the retinal microvasculature that will provide an increase in the quality of images captured and will be applied throughout the various animal cohorts of the recentlyinitiated study that will evaluate rodent HS as a model to study ophthalmic complications in microgravity.

Theriot, Corey A.↗

Curved Diffractive X-ray Optics for X-ray Astronomy

We report on a concept for curved diffractive X-ray optics (CDXO). CDXO would enable potential new optical designs for X-ray instruments, such as a two element spectrometer, in which the secondary element of an X-ray mirror pair is patterned with an X-ray grating. A two-element spectrometer design eliminates the grating assembly, resulting in decreased instrument mass and reduced power requirements. In addition, a two-element spectrometer may realize cost/schedule savings by eliminating a separate grating alignment effort, and yield increased effective area over three element designs. We present a raytrace concept study of a two-element spectrometer compact enough to fit within a sounding rocket payload. We also review the progress made in electron-beam lithography (EBL) techniques that would enable curved diffractive X-ray optics to be patterned, and outline a procedure by which the accuracy of the EBL patterning process can be measured interferometrically.

Casey T. DeRoo↗

Magnetotail views at 33R(sub E): IMP 8 magnetometer observations

This paper presents magnetic field vector (B) maps, electric current vector (curl B) maps, magnetic force (JxB) contour maps, and total field contour maps covering the full tail cross section in the yz plane. The maps are based on 16 years of 5-min averages of Interplanetary Monitoring Platform (IMP) 8 magnetic field data. During this time, IMP 8 traversed the tail between -25R(sub E) and -40R(sub E) in the x direction. Its average x distance was -33R(sub E). For this average distance we show separate maps for low and high dipole tilts, corresponding to equinox and northern hemisphere summer seasons. The low-tilt (equinox) maps show symmetrical field and current patterns; the high-tilt (solstice) maps show the cross-tail current sheet arcing above the equatorial diagonal in the center and dipping below it on the flanks. The shape of warped current sheet fits Fairfield's (1980) displaced ellipse model fairly well. The distance at which the current sheet is hinged to the magnetic equator is found to be 9.88R(sub E) and is independent of Kp. The z profile of current density shows a central peak, 3R(sub E) full width at half maximum, and smaller, flanking shoulders. A Harris sheet profile with a 7R(sub E) thickness fits the B(sub x) profile. Though these are magnetic field data, the JxB maps clearly outline the plasma sheet. This approach also gives 7R(sub E) thickness. Many of the average field and current features inferred and demonstrated in earlier studies are confirmed here; some of them are seen for the first time in full cross-section view. Among new features revealed are a large current vortex in the winter hemisphere lobe, a dawn-dusk asymmetry in the JxB force in the plasma sheet (it is stronger on the duskside), and a separation of the cross-tail current sheet into core and wing parts.

Kaymaz, Zerefsan↗

Exploratory flight investigation of aircraft response to the wing vortex wake generated by jet transport aircraft

The effect of intercepting wing tip vortices generated by large jet transports, including jumbo jets, over separation distances from 1 nautical mile to 15 nautical miles is evaluated on the basis of the response of a vortex probe airplane in the roil mode. The vortex probe test aircraft included a representative general aviation airplane, an executive jet, a fighter, and light and medium weight jet transports. The test conditions and airplane configurations were comparable to those normally used during takeoff, landing, or holding pattern operations. For flight safety the tests were performed at altitudes from 9500 feet to 12,500 feet. In addition to an evaluation of the probe airplane response, a flight test technique is suggested for determining minimum separation distance, using as variable the ratio of vortex-induced roll acceleration to maximum lateral control acceleration and the gross weight of the generating aircraft.

Andrews, W. H.↗

Time series analysis of compressor noise.

Description of a method to determine compressor directivity at discrete frequencies by separation of the tone power from the noise background. The technique developed effected the separation by Fourier analysis of the sound pressure autocorrelation at large lags. This produced experimental directivity results which compared reasonably well with the theoretical patterns except near the compressor axis.

Hardin, J. C.↗

Agricultural land use mapping

The author has identified the following significant results. Agricultural areas were selected or analysis in southeastern Pennsylvania, north central Montana, and southern Texas. These three sites represent a broad range of soils, soil parent materials, climate, modes of agricultural operation, crops, and field sizes. In each of these three sites, ERTS-1 digital data were processed to determine the feasibility of automatically mapping agricultural land use. In Pennsylvania, forest land, cultivated land, and water were separable within a 25,000 acre area. Four classes of water were also classified and identified, using ground truth. A less complex land use pattern was analyzed in Hill County, Montana. A land use map was prepared shown alternating patterns of summer fallow and stubble fields. The location of farmsteads could be inferred, along with that of a railroad line. A river and a creek flowing into the river were discernible. Six categories of water, related to sediment content and depth, were defined in the reservoir held by the Fresno dam. These classifications were completed on a 150 square mile area. Analysis of the data from Texas is in its formative stages. A test site has been selected and a brightness map has been produced.

Mcmurtry, G. J.↗

Intermode calibration of diode-laser spectra using tandem etalons

The paper deals with an approach which can improve the accuracy of etalon calibration of tunable diode-laser (TDL) spectra in the IR and extend absolute calibration among several isolated modes. Two etalons placed in the laser beam produce a combined fringe pattern that, with the aid of a monochromator mode selector, can be used to establish the number of fringes between any two spectral points separated by a large frequency interval. This technique has been applied to several similar cases for calibration of isolated modes or verification of the identity of lines of known frequency.

Jennings, D. E.↗

Crop identification studies using Landsat data Separation of barley from other spring small grains and corn and soybean decision logic

Two labeling procedures were developed which identify various agricultural crops through the use of Landsat data. One procedure separates barley from other spring small grains, and the other identifies corn and soybeans. For both procedures, a minimum data set (critical acquisition time) has been designated. Landsat data in both image format and various graphic displays were used along with ancillary data to obtain information which aided in labeling the spectral signatures. The corn and soybean procedure also employed a structured decision logic. Test results for the barley separation procedure emphasized the importance of obtaining a critical acquisition and showed some success especially in areas where spring crops followed the expected growth patterns. Two tests of the corn and soybean procedure produced good labeling accuracies. Problems with the procedure were easy to identify, and some solutions were implemented for the second test. Automation of various parts of the procedure and extension to other crops and regions were recommended.

Dailey, C. L.↗

Hotspots, basalts, and the evolution of the mantle

It is noted that the trace element concentration patterns of continental and ocean island basalts and of mid-ocean ridge basalts are complementary. Estimates of the relative sizes of the source regions for these fundamentally different basalt types can be arrived at from the trace element enrichment-depletion patterns. Their combined volume occupies the greater part of the mantle above the 670 km discontinuity. It is pointed out that the source regions separated as a result of early mantle differentiation and crystal fractionation from the resulting melt. The mid-ocean ridge basalts source evolved from an eclogite cumulate that gave up its late-stage enriched fluids at various times to the shallower mantle and continental crust. The mid-ocean ridge basalts source is rich in garnet and clinopyroxene, while the continental and ocean island basalt source is a garnet peridotite that has experienced secondary enrichment. These relationships are found to be consistent with the evolution of a terrestrial magma ocean.

Anderson, D. L.↗

A psychophysiological assessment of operator workload during simulated flight missions

The applicability of the dual-task event-related (brain) potential (ERP) paradigm to the assessment of an operator's mental workload and residual capacity in a complex situation of a flight mission was demonstrated using ERP measurements and subjective workload ratings of student pilots flying a fixed-based single-engine simulator. Data were collected during two separate 45-min flights differing in difficulty; flight demands were examined by dividing each flight into four segments: takeoff, straight and level flight, holding patterns, and landings. The P300 ERP component in particular was found to discriminate among the levels of task difficulty in a systematic manner, decreasing in amplitude with an increase in task demands. The P300 amplitude is shown to be negatively correlated with deviations from command headings across the four flight segments.

Kramer, Arthur F.↗

Currents between tethered electrodes in a magnetized laboratory plasma

Laboratory experiments on important plasma physics issues of electrodynamic tethers were performed. These included current propagation, formation of wave wings, limits of current collection, nonlinear effects and instabilities, charging phenomena, and characteristics of transmission lines in plasmas. The experiments were conducted in a large afterglow plasma. The current system was established with a small electron-emitting hot cathode tethered to an electron-collecting anode, both movable across the magnetic field and energized by potential difference up to V approx.=100 T(sub e). The total current density in space and time was obtained from complete measurements of the perturbed magnetic field. The fast spacecraft motion was reproduced in the laboratory by moving the tethered electrodes in small increments, applying delayed current pulses, and reconstructing the net field by a linear superposition of locally emitted wavelets. With this technique, the small-amplitude dc current pattern is shown to form whistler wings at each electrode instead of the generally accepted Alfven wings. For the beam electrode, the whistler wing separates from the field-aligned beam which carries no net current. Large amplitude return currents to a stationary anode generate current-driven microinstabilities, parallel electric fields, ion depletions, current disruptions and time-varying electrode charging. At appropriately high potentials and neutral densities, excess neutrals are ionized near the anode. The anode sheath emits high-frequency electron transit-time oscillations at the sheath-plasma resonance. The beam generates Langmuir turbulence, ion sound turbulence, electron heating, space charge fields, and Hall currents. An insulated, perfectly conducting transmission line embedded in the plasma becomes lossy due to excitation of whistler waves and magnetic field diffusion effects. The implications of the laboratory observations on electrodynamic tethers in space are discussed.

Stenzel, R. L.↗

A Three-Dimensional Coupled Internal/External Simulation of a Film-Cooled Turbine Vane

A three-dimensional Navier-Stokes simulation has been performed for a realistic film-cooled turbine vane using the LeRC-HT code. The simulation includes the flow regions inside the coolant plena and film cooling holes in addition to the external flow. The vane is the subject of an upcoming NASA Glenn Research Center experiment and has both circular cross-section and shaped film cooling holes. This complex geometry is modeled using a multi-block grid which accurately discretizes the actual vane geometry including shaped holes. The simulation matches operating conditions for the planned experiment and assumes periodicity in the spanwise direction on the scale of one pitch of the film cooling hole pattern. Two computations were performed for different isothermal wall temperatures, allowing independent determination of heat transfer coefficients and film effectiveness values. The results indicate separate localized regions of high heat transfer coefficient values, while the shaped holes provide a reduction in heat flux through both parameters. Hole exit data indicate rather simple skewed profiles for the round holes, but complex profiles for the shaped holes with mass fluxes skewed strongly toward their leading edges.

Heidmann, James D.↗

Complexity Management Using Metrics for Trajectory Flexibility Preservation and Constraint Minimization

The growing demand for air travel is increasing the need for mitigating air traffic congestion and complexity problems, which are already at high levels. At the same time new surveillance, navigation, and communication technologies are enabling major transformations in the air traffic management system, including net-based information sharing and collaboration, performance-based access to airspace resources, and trajectory-based rather than clearance-based operations. The new system will feature different schemes for allocating tasks and responsibilities between the ground and airborne agents and between the human and automation, with potential capacity and cost benefits. Therefore, complexity management requires new metrics and methods that can support these new schemes. This paper presents metrics and methods for preserving trajectory flexibility that have been proposed to support a trajectory-based approach for complexity management by airborne or ground-based systems. It presents extensions to these metrics as well as to the initial research conducted to investigate the hypothesis that using these metrics to guide user and service provider actions will naturally mitigate traffic complexity. The analysis showed promising results in that: (1) Trajectory flexibility preservation mitigated traffic complexity as indicated by inducing self-organization in the traffic patterns and lowering traffic complexity indicators such as dynamic density and traffic entropy. (2)Trajectory flexibility preservation reduced the potential for secondary conflicts in separation assurance. (3) Trajectory flexibility metrics showed potential application to support user and service provider negotiations for minimizing the constraints imposed on trajectories without jeopardizing their objectives.

Idris, Husni↗

Engineered Multifunctional Surfaces for Fluid Handling

Designs incorporating variations in capillary geometry and hydrophilic and/or antibacterial surface properties have been developed that are capable of passive gas/liquid separation and passive water flow. These designs can incorporate capillary grooves and/or surfaces arranged to create linear and circumferential capillary geometry at the micro and macro scale, radial fin configurations, micro holes and patterns, and combinations of the above. The antibacterial property of this design inhibits the growth of bacteria or the development of biofilm. The hydrophilic property reduces the water contact angle with a treated substrate such that water spreads into a thin layer atop the treated surface. These antibacterial and hydrophilic properties applied to a thermally conductive surface, combined with capillary geometry, create a novel heat exchanger capable of condensing water from a humid, two-phase water and gas flow onto the treated heat exchanger surfaces, and passively separating the condensed water from the gas flow in a reduced gravity application. The overall process to generate the antibacterial and hydrophilic properties includes multiple steps to generate the two different surface properties, and can be divided into two major steps. Step 1 uses a magnetron-based sputtering technique to implant the silver atoms into the base material. A layer of silver is built up on top of the base material. Completion of this step provides the antibacterial property. Step 2 uses a cold-plasma technique to generate the hydrophilic surface property on top of the silver layer generated in Step 1. Completion of this step provides the hydrophilic property in addition to the antibacterial property. Thermally conductive materials are fabricated and then treated to create the antibacterial and hydrophilic surface properties. The individual parts are assembled to create a condensing heat exchanger with antibacterial and hydrophilic surface properties and capillary geometry, which is capable of passive phase separation in a reduced gravity application. The plasma processes for creating antibacterial and hydrophilic surface properties are suitable for applications where water is present on an exposed surface for an extended time, such that bacteria or biofilms could form, and where there is a need to manage the water on the surface. The processes are also suitable for applications where only the hydrophilic property is needed. In particular, the processes are applicable to condensing heat exchangers (CHXs), which benefit from the antibacterial properties as well as the hydrophilic properties. Water condensing onto the control surfaces of the CHX will provide the moist conditions necessary for the growth of bacteria and the formation of biofilms. The antibacterial properties of the base layer (silver) will mitigate and prevent the growth of bacteria and formation of biofilms that would otherwise reduce the CHX performance. In addition, the hydrophilic properties reduce the water contact angle and prevent water droplets from bridging between control surfaces. Overall, the hydrophilic properties reduce the pressure drop across the CHX.

Thomas, Chris↗

Evolution of Dendritic Extended 3D Patterns during Directional Solidification: Microgravity Experiments in DECLIC-DSI onboard ISS and Phase-field Modeling

To characterize the dynamical formation of three-dimensional (3D) arrays of dendrites under diffusive growth conditions, in situ monitoring of a series of experiments on a transparent succinonitrile – 0.46 wt% camphor model alloy was carried out under low gravity in the DECLIC Directional Solidification Insert onboard the International Space Station. These experiments offer continuous interface observation and enable the construction of space-time evolution maps of dendrite location and primary spacing during directional solidification. We present the evolution of dendritic extended 3D patterns for a large range of parameters displaying different levels of side branching in both experiments and phase-field simulations. The combined and separate effects of macroscopic interface curvature and crystal mis-orientation are evidenced and detailed. In addition, the aligned dendritic array caused by the invasion of dendrites formed at the edge of the crucible border is investigated.

Kaihua Ji↗

Multi-Dimensional Damage Detection for Surfaces and Structures

Current designs for inflatable or semi-rigidized structures for habitats and space applications use a multiple-layer construction, alternating thin layers with thicker, stronger layers, which produces a layered composite structure that is much better at resisting damage. Even though such composite structures or layered systems are robust, they can still be susceptible to penetration damage. The ability to detect damage to surfaces of inflatable or semi-rigid habitat structures is of great interest to NASA. Damage caused by impacts of foreign objects such as micrometeorites can rupture the shell of these structures, causing loss of critical hardware and/or the life of the crew. While not all impacts will have a catastrophic result, it will be very important to identify and locate areas of the exterior shell that have been damaged by impacts so that repairs (or other provisions) can be made to reduce the probability of shell wall rupture. This disclosure describes a system that will provide real-time data regarding the health of the inflatable shell or rigidized structures, and information related to the location and depth of impact damage. The innovation described here is a method of determining the size, location, and direction of damage in a multilayered structure. In the multi-dimensional damage detection system, layers of two-dimensional thin film detection layers are used to form a layered composite, with non-detection layers separating the detection layers. The non-detection layers may be either thicker or thinner than the detection layers. The thin-film damage detection layers are thin films of materials with a conductive grid or striped pattern. The conductive pattern may be applied by several methods, including printing, plating, sputtering, photolithography, and etching, and can include as many detection layers that are necessary for the structure construction or to afford the detection detail level required. The damage is detected using a detector or sensory system, which may include a time domain reflectometer, resistivity monitoring hardware, or other resistance-based systems. To begin, a layered composite consisting of thin-film damage detection layers separated by non-damage detection layers is fabricated. The damage detection layers are attached to a detector that provides details regarding the physical health of each detection layer individually. If damage occurs to any of the detection layers, a change in the electrical properties of the detection layers damaged occurs, and a response is generated. Real-time analysis of these responses will provide details regarding the depth, location, and size estimation of the damage. Multiple damages can be detected, and the extent (depth) of the damage can be used to generate prognostic information related to the expected lifetime of the layered composite system. The detection system can be fabricated very easily using off-the-shelf equipment, and the detection algorithms can be written and updated (as needed) to provide the level of detail needed based on the system being monitored. Connecting to the thin film detection layers is very easy as well. The truly unique feature of the system is its flexibility; the system can be designed to gather as much (or as little) information as the end user feels necessary. Individual detection layers can be turned on or off as necessary, and algorithms can be used to optimize performance. The system can be used to generate both diagnostic and prognostic information related to the health of layer composite structures, which will be essential if such systems are utilized for space exploration. The technology is also applicable to other in-situ health monitoring systems for structure integrity.

Williams, Martha↗

Utilization of ERTS-1 data to monitor and classify eutrophication of inland lakes

The author has identified the following significant results. Significant findings are: (1) one-acre lakes and one-acre islands are detectable; (2)removal of atmospheric parameters derived from RPMI measurements show test lakes to have reflectances of 3.1 to 5.5% in band 4 and 0.3 to 2.3% in band 5; (3) failure to remove reflectance caused by atmosphere results in errors up to 500% in computing lake reflectance from ERTS-1 data; (4) in band 4, up to seven reflectance levels were observed in test lakes; (5) reflectance patterns have been displayed on a color-coded TV monitor and on computer-generated gray scales; (6) deep and shallow water can be separated by a trained photointerpreter and automatic machine processing, with estimates of water depth possible in some cases; (7) RPMI provides direct spectral signature measurements of lakes and lake features such as algal scums and floating plants; (8) a method is reported for obtaining lake color, as estimated by Forel-Ule standards, from ERTS-1 data; (9) a strong correlation between browner water color, diminishing water transparency; and (10) classifying lake eutrophication by observation of surface scums or macrophytes in shallow water seems straightforward.

Rogers, R. H.↗

Some aspects of calculating flows about three-dimensional subsonic inlets

Various three dimensional inlet models were calculated based on the potential flow model. Results are presented in the forms of surface static pressure, flow angularity, surface flow pattern, and inlet flow field. It is indicated that the extension of the lower lip can reduce the adverse pressure gradient and increase the flow separation bound.

Kao, H. C.↗