SEARCH · Engineering Papers

Results for “evaluation platform”

Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

SourceResearch connectionFrom yearThrough year

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 415 records · Page 23

All sources NASA NTRS DOE OSTI

DOE OSTI2024

Energy Efficiency Analysis and Grid Service Results for Commercial Buildings using the VOLTRON IoT Platform

In fiscal year 2021 (FY21), the Commercial Buildings Integration Program (CBI) within the Building Technologies Office (BTO), funded PNNL to conduct a field evaluation of the AIRCx and ILC using an Internet-of-Things (IoT) platform, VOLTTRON. The primary goal of the project is to show that software solutions deployed and delivered through an IoT-platform can identify energy efficiency opportunities and manage peak load (beyond the traditional demand response) in commercial buildings. There are also two secondary goals: 1) show that the energy efficiency solutions will result in identification of significant savings opportunities (10% to 30%) as well as energy cost reductions (10% to 15%) by managing the peak load in commercial buildings, and 2) show that an IoT-based software solution is more cost-effective compared to a manual process in meeting the Re-tuning/retro commissioning (RCx) mandates and there is a pathway for broader adoption of this approach. This report provides AIRCx and ILC results for two building located in District of Columbia managed by the energy service provider Intellimation.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗

DOE OSTI2022

AI-Enabled Robots for Automated Nondestructive Evaluation and Repair of Power Plant Boilers. Final Report

Boiler failure could cause loss of life and safety issues, cost hundreds of thousands of dollars in equipment repairs, property damage and production losses, and drive up the cost of electric power. Boiler maintenance is challenging and risky for inspectors working on scaffolding in confined hazardous spaces inside of a boiler and sometimes the space is hard to access. The operation is also time-consuming due to the large area of vertical structures for inspection and the tremendous effort needed for scaffolding. Recently, the use of robotics (e.g., drones and crawlers) in power plants for maintenance is growing rapidly. However, the existing robotics solutions show two notable technological gaps: no live repair capability, and no Artificial Intelligence (AI) for smart autonomy. The objective of this project is to develop an integrated autonomous robotic platform that is equipped with compact non-destructive evaluation (NDE) sensors to perform live inspection, operates onboard repair devices to perform live repair, and uses AI for intelligent data fusion and predictive analysis for automated and smart spatiotemporal inspection, analysis and repair of the furnace walls in coal-fired boilers. The approach to achieve the objective includes developing NDE sensors with signal processing techniques, designing and evaluating repair devices for robots based on fusion and solid-state technologies, and an autonomous robotic platform that can attach to and navigate on boiler furnace walls using magnetic drive tracks. The robot is also powered by AI to automate data gathering (e.g., 3D mapping and damage localization) and predictive analysis. This project has advanced the state-of-the-art by providing technological breakthroughs including compact NDE and repair tools for robots, AI capabilities for smart autonomy, and a robotic platform for automated boiler maintenance. This project has great potential to result in significant benefits including limiting or eliminating the need to send operators to assess difficult-to-access or hazardous areas, enabling automated live inspection and repair, avoiding time consuming scaffolding (especially for partial maintenance during unplanned outage), collecting comprehensive and well-organized data smartly, and avoiding or limiting the need for onsite or remote piloting technicians. The impacts can be tremendous in terms of the time and cost savings, reducing the risk for human operators, and increasing boiler reliability, usability, and efficiency. In addition, by developing the new technologies on the autonomous inspection and repair robot, by involving multiple undergraduate and graduate students working together with the faculty members on this project, and by generating knowledge and building up collaborations with industrial partners, this effort will significantly update the education capabilities, support long-term fundamental research, and maintain the leadership of Colorado School of Mines and Michigan State University in energy fields.

20 FOSSIL-FUELED POWER PLANTS↗

DOE OSTI2018

Radioactive Test Platform Demonstrating the Direct Feed Low-Activity Waste Process at Hanford - 18628

The Hanford Site is implementing a phased process for treating liquid legacy radioactive waste. The process is called the Direct Feed Low-Activity Waste process (DFLAW). The DFLAW includes a filtration and ion-exchange unit in the Low-Activity Waste Pretreatment System (LAWPS) that removes solids and cesium. This pretreat feed is then sent to a vitrification facility where glass-forming solids are added and the waste is turned into glass in a melter. The melter off-gas liquid condensate is evaporated in the Effluent Management Facility (EMF), with the concentrate recycled back into the feed. A laboratory-scale test platform has been built to test various aspects of the DFLAW process using samples of actual radioactive waste. The current platform represents four of the major unit operations: filtration, ion-exchange, vitrification, and off-gas condensation. A lab scale EMF is being designed to supplement the current platform. The platform is expandable to add any or all unit operations. The radioactive test platform has three missions. The first is simply to demonstrate the DFLAW process with real waste. A second objective is to address flowsheet gaps and opportunities, some of which require testing with real waste. Some gaps and opportunities include addressing the fate of mercury in the flowsheet, evaluating salt and aluminum precipitation, and proving new glass formulations with real waste. A third objective of the radioactive test platform is to demonstrate or evaluate future operations and alternative flowsheets. Some of the future operations evaluated will be the life expectancy of the resin in real waste, resin sampling, evaluation of how waste affects melter throughput, and grouting various primary and secondary waste streams. The radioactive test platform is therefore a crucial tool for verifying and optimizing the DFLAW flowsheet at Hanford with real waste. (authors)

12 MANAGEMENT OF RADIOACTIVE AND NON-RADIOACTIVE W↗

NASA NTRS1998

Automated Generation of Message-Passing Programs: An Evaluation Using CAPTools

Scientists at NASA Ames Research Center have been developing computational aeroscience applications on highly parallel architectures over the past ten years. During that same time period, a steady transition of hardware and system software also occurred, forcing us to expend great efforts into migrating and re-coding our applications. As applications and machine architectures become increasingly complex, the cost and time required for this process will become prohibitive. In this paper, we present the first set of results in our evaluation of interactive parallelization tools. In particular, we evaluate CAPTool's ability to parallelize computational aeroscience applications. CAPTools was tested on serial versions of the NAS Parallel Benchmarks and ARC3D, a computational fluid dynamics application, on two platforms: the SGI Origin 2000 and the Cray T3E. This evaluation includes performance, amount of user interaction required, limitations and portability. Based on these results, a discussion on the feasibility of computer aided parallelization of aerospace applications is presented along with suggestions for future work.

Hribar, Michelle R.↗

NASA NTRS2002

Automated Generation of Message-Passing Programs: An Evaluation Using CAPTools

Hribar, Michelle R.↗

DOE OSTI2026

AutoBEM: A scalable framework for nationwide building energy simulation and retrofit evaluation in the United States

This paper presents AutoBEM, an integrated, automated framework for nationwide building energy modeling and retrofit evaluation in the United States. Unlike prior UBEM platforms that either rely primarily on representative stock sampling or operate at city scale, AutoBEM automates the generation of building-resolved, physics-based EnergyPlus/OpenStudio simulation models at national scale using GIS-derived geometry, prototype-based assumptions, and standardized scalable workflows. Leveraging the Model America dataset and high-performance computing, AutoBEM generates and simulates energy models for 122.9 million buildings, representing 97.8% of the U.S. building stock. These models are being made publicly and freely available as the Model America v1.0 (MAv1) dataset. AutoBEM supports detailed, building-level assessments of energy consumption, CO2 emissions, and post-processed anthropogenic heat emissions (AHE), and evaluates 151 energy conservation measures (ECMs) using localized utility pricing and building characteristics. In addition, AutoBEM incorporates both typical and future climate conditions through integration with Typical Meteorological Year (TMY) and Future TMY (fTMY) weather data derived from IPCC scenarios. In a case study of Phoenix, Arizona, AutoBEM identified several high-efficiency HVAC upgrades and selected envelope measures with short modeled payback periods (1.5 years) for certain building types and standards. Simulations under future climate scenarios (SSP5–RCP8.5) project an 11.3% increase in electricity use and a 32% reduction in natural gas demand by 2100, underscoring the need for climate-adaptive retrofit planning. By enabling reproducible, bottom-up, and location-specific analysis at scale, AutoBEM provides a step toward a national digital twin of the built environment and supports data-driven screening and planning for decarbonization, resilience, and energy equity.

Li, Hang [ORNL] (ORCID:0000000306001920)↗

DOE OSTI2026

Rapid Evaluation of Amine-Functionalized Solvents for Biomass Deconstruction Using High-Throughput Screening and One-Pot Enzymatic Saccharification

Efficient and sustainable pretreatment of lignocellulosic biomass is critical for biofuel and biochemical production, yet its optimization is often hindered by slow, labor-intensive experimental methods. Here, we report the first demonstration of a custom-built, miniaturized, high-throughput screening platform integrated with one-pot enzymatic saccharification, enabling parallel evaluation of solvent type, feedstock, and temperature with minimal material use and high reproducibility. As a proof-of-concept, the HTX platform was used to screen five amine-functionalized solvents, including isopropanolamine, butylamine, N-methylbutylamine, ethanolamine, and ethanolamine acetate across three bioenergy crops (sorghum, poplar, and switchgrass) and pretreatment temperatures ranging from 80 to 140 °C. Vacuum drying successfully removed more than 99% of the solvents from the pretreated biomass, eliminating the need for water washing prior to saccharification. Isopropanolamine and N-methylbutylamine yielded the highest glucose (70–80%) and xylose (58–67%) release, with trends reflecting feedstock recalcitrance. The produced hydrolysates supported robust growth of an engineered strain of the yeast Rhodosporidium toruloides, confirming biocompatibility. This high-throughput platform provides a scalable, feedstock-agnostic framework for rapid pretreatment screening, accelerating solvent–feedstock pairing and process optimization. Its ability to integrate pretreatment, solvent removal, saccharification, and microbial conversion in a miniaturized format offers significant advantages for cost-competitive biorefinery development.

Biomass↗

NASA NTRS2010

Platform for Post-Processing Waveform-Based NDE

Signal- and image-processing methods are commonly needed to extract information from the waves, improve resolution of, and highlight defects in an image. Since some similarity exists for all waveform-based nondestructive evaluation (NDE) methods, it would seem that a common software platform containing multiple signal- and image-processing techniques to process the waveforms and images makes sense where multiple techniques, scientists, engineers, and organizations are involved. NDE Wave & Image Processor Version 2.0 software provides a single, integrated signal- and image-processing and analysis environment for total NDE data processing and analysis. It brings some of the most useful algorithms developed for NDE over the past 20 years into a commercial-grade product. The software can import signal/spectroscopic data, image data, and image series data. This software offers the user hundreds of basic and advanced signal- and image-processing capabilities including esoteric 1D and 2D wavelet-based de-noising, de-trending, and filtering. Batch processing is included for signal- and image-processing capability so that an optimized sequence of processing operations can be applied to entire folders of signals, spectra, and images. Additionally, an extensive interactive model-based curve-fitting facility has been included to allow fitting of spectroscopy data such as from Raman spectroscopy. An extensive joint-time frequency module is included for analysis of non-stationary or transient data such as that from acoustic emission, vibration, or earthquake data.

Roth, Don J.↗

NASA NTRSDate not supplied

Network Emulation Testbed Capabilities for Prototyping Space DTN Software and Protocols

This paper delves into network emulation tools essential for evaluating and designing Delay Tolerant Networking (DTN) protocols in space and satellite networking. It surveys and assesses the capability of current testbeds to create realistic test environments crucial for developing and evaluating DTN protocols. Specifically, this study provides a comprehensive overview of key DTN protocol stacks and related network emulation platforms and a detailed exploration of NASA’s research facilities. Finally, the paper underscores the fundamental emulation capabilities and the importance of a standardized framework for scenario creation, highlighting its vital role in evaluating and advancing future emulation platforms for space DTN.

Network Emulation and Simulation↗

NASA NTRS1982

Evaluation of ERIM optically processed SEASAT SAR data

The results of three studies on the radiometric and geometric properties of optically processed SEASAT SAR imagery are summarized. The accuracy with which the image scale can be predicted based upon a knowledge of the SAR platform and recording system parameters and the processor characteristics was evaluated. The considerations involved in making radiometric measurements from image films, the use of point targets for calibrating the effects of Doppler spectrum shifts on the radiometric calibration of the SAR image data over extended swath lengths was evaluated

Shuchman, R. A.↗

DOE OSTI2020

Development of a Reference Design for a Cyber-Physical System

The purpose of this thesis is to develop a reference design to assist in the selection of security practices in power electronics design. A prototype will be developed from this reference design for evaluation. This evaluation will include a brief cost/benefit analysis to gauge the efficacy of implementing each layer of security throughout the power electronics design process. This thesis will also describe the obstacles and effectiveness of integrating a Trusted Platform Module (TPM) into a cyber-hardened grid-connected device. The TPM device is a secured crypto processor that assists in generating, storing, and restricting the use of cryptographic keys. The emphasis of this research is to establish integrity, authenticity, and confidentiality within a system by providing a baseline of security concerns for segments of the system. This research considers communication, control, and hardware level securities. The scope of this thesis will review the necessary security methods as well as consider the effects these methods have on the embedded system, to assess the desired security to responsiveness trade off. Applying this approach to a design process will alleviate various unknowns of appending security to a power electronics design. This thesis describes the specific vulnerabilities introduced within this grid-edge environment, and how the liabilities within the system can be mitigated. Initially, common security techniques will be considered to establish a guideline to benchmark performance and resource costs of the system. The foundation will be a non-hardened power electronic system platform with industry standard communication protocols. Several security techniques and attack vectors will then be evaluated to contribute to the base level platform. Other fail-safe features take place to gauge progress of the selected approach, non-inclusive to the TPM. Collectively, this investigation will determine a valid experiment by appraising and categorizing resource allocation, performance overhead, and monetary cost analysis results into a reference design. The prototype will then demonstrate methods to relieve common threats that are purposefully implemented into the design.

Blair, Nicholas Paul↗

DOE OSTI2020

Density Matrix Quantum Circuit Simulation via the BSP Machine on Modern GPU Clusters

As quantum computers evolve, simulations of quantum programs on classical computers will be essential in validating quantum algorithms, understanding the effect of system noise, and design applications for future quantum computers. In this paper, we propose a novel multi-GPU programming model called MG-BSP that constructs a virtual BSP machine on top of modern multi-GPU platforms, and tweak the programming model to build a multi-GPU density matrix quantum simulator. We propose and evaluated a new formulation minimizing communication and prove that the transformation conserves original semantics when noise is introduced. We build the tool-chain to support quantum assembly open standard, synthesize testing quantum circuit, and enable ultra-deep quantum simulation. We evaluated our design on four state-of-the-art multi-GPU platforms including the latest DGX-1 and DGX-2 systems. We demonstrate simulation of 1 million gates in 94 minutes, far deeper circuits than has been demonstrated in prior work. A roofline-model analysis show that we have reached near-optimal performance under memory bound.

Li, Ang↗

DOE OSTI2019

Coupling of an atmospheric pressure microplasma ionization source with an Orbitrap Fusion Lumos Tribrid 1M mass analyzer for ultra-high resolution isotopic analysis of uranium

The coupling of a combined atomic and molecular (CAM) ionization source, the liquid sampling-atmospheric pressure glow discharge (LS-APGD) microplasma to an Orbitrap Fusion Lumos Tribrid 1M mass spectrometer is described as a significant step towards the elimination of isobaric interferences in elemental/isotopic mass spectrometry. The developed setup permits broadband, elemental mass spectra to be easily acquired at a mass resolution (m/Δm) of 500 000. A new ion source housing and integrated control system provide enhanced stability and sensitivity of the microplasma ion source in comparison to the previous designs. Detailed evaluation of the ion sampling parameters provided insight into differences with other Orbitrap platforms leading to a 5-fold increase in resolution in elemental/isotopic analysis. The roles of data acquisition/ion processing parameters were evaluated with regards to the precision and accuracy of 235 U/ 238 U isotope ratios. Significantly, the precision of those measurements improves as a function of pre-set mass resolution up to a value of 1 000 000, where a precision of 0.086% RSD is obtained for uranium concentrations of 100 ng mL− 1 . Analytical response curves (log–log), acquired for the two uranium isotopes at a resolution of 120 000 were linear (R 2 = 0.9969) over more than 5 orders of magnitude, with limits of detection of 1 pg mL −1 for U. Based on 60 μL injection volumes, this represents a mass of 70 fg 235 U. These figures of merit satisfy International Target Values (ITVs) for Measurement Uncertainties in Safeguarding Nuclear Materials set by the International Atomic Energy Agency (IAEA). Ultimately, and totally unique from beam-type instruments, the move to the higher-resolution Orbitrap platform provides all of the benefits of high mass resolution, with no penalties in sensitivity, precision, or dynamic range for uranium analysis.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

DOE OSTI2023

Control System of Multi-Port Autonomous Reconfigurable Solar Power Plant (MARS) & HIL Platforms for Design

Multi-port autonomous reconfigurable solar power plant (MARS) provides an attractive alternative to connect photovoltaic (PV) and energy storage systems (ESSs) to high-voltage direct current (HVdc) links and high-voltage alternating current (ac) grids. In this paper, a unique hierarchical control system of MARS is proposed and evaluated. To evaluate the control system and associated algorithms in early-stage research of complex architectures like MARS, it is important to develop unique suitable hardware-in-the-loop (HIL) platforms. In this paper, the HIL platforms for MARS to evaluate the performance of the hierarchical control system and the control algorithms implemented are presented. Further, they help with the design process of control systems. The real-time simulation models and algorithms that are utilized for MARS in the HIL platforms are also discussed in the paper. The HIL experiments of the control system of MARS showcase the capability to provide continuity of operation under faults and frequency support to the power grid during loss of generation. They also showcase the stability of the proposed hierarchical control system of MARS.

14 SOLAR ENERGY↗

NASA NTRSDate not supplied

Lunar Node – 1: Initial Flight Results and the Role of Surface Psuedolites in Lunar Navigation

On February 22, 2024, the Intuitive Machines IM-1 NOVA-C lander, nick-named Odysseus, landed on the lunar surface, carrying with it a cadre of NASA scientific and technology demonstration payloads. These payloads and missions marked the first delivery of NASA instruments to operate from the lunar surface since the Apollo landings. One of these payloads is Lunar Node -1 (LN-1), a navigation beacon demonstration mission. The payload was designed and built by NASA’s Marshall Space Flight Center. The payload’s main goal was to demonstrate and provide insight into the use of lunar surface-based radio navigation aids. As part of the mission, LN-1 successfully conducted multiple one-way transmissions from the NOVA-C vehicle to Deep Space Network ground receivers using its onboard S-band transmitter, while being disciplined by an onboard Space Chip Scale Atomic Clock. LN-1 transmitted to DSN on an almost daily basis during transit to the moon, including two surface passes. The payload was originally plan to conduct 7-10 days of surface operation as an always-on beacon. These passes focused on evaluating two main navigation approaches: performance and stability of ranging using time-based transfer techniques on a cubesat size and grade platform, as well as one-way psuedonoise ranging approaches. To assess performance, the measurements were compared to independent navigation solutions using multiple approaches including: one-way Doppler tracking, two-way Doppler Tracking, and visual verification of the landing location provided by visual observations from orbital platforms. While the mission only conducted limited surface operations, the data provides some initial insight to performance form the lunar surface. These results are compared with initial ground-based testing as well as continued evaluation of the flight-space platform using multiple grades of oscillators for maintaining clock and frequency stability. These focus on the timing stability of platform in a deep-space environment as well variations in state determination. Given these insights, this paper provides additional description and evaluation of how this approach can be utilized as part of a broader lunar navigation architecture, such as being developed and deployed across multiple international space agencies. Analysis is provided to develop overall timing requirements and assessment of operational scenarios, such as orbit and surface location determination. In addition, the results support discussion as to how surface pseudolites could best be used within existing standard signal definitions, such as defined in the LunaNet Interoperability Specifications. This will consider concerns such as the near-/far- problem as well as operational considerations, including whether a beacon is better suited as two- or one-way ranging platform. The use cases are focused on how these psuedolites can provide additional coverage to augment and support planned operational coverage. For example, this analysis provides analysis of mid-latitude surface missions, where there may be limited geometry and availability of orbital relays. The results will show how these navigation psuedolites can fit within the developing architecture to provide additional robustness, capability, and support multiple use cases. Lastly, the paper will discuss challenges and next steps to be addressed in the implementation and testing of a follow-on payload and a continued path towards demonstration and integration of this capability into Lunar PNT architectures.

Evan Anzalone↗

NASA NTRSDate not supplied

Lunar Node – 1: Initial Flight Results and the Role of Surface Psuedolites in Lunar Navigation

On February 22, 2024, Intuitive Machines NOVA-C lander, nick-named Odysseus, landed on the lunar surface, carrying with it a cadre of NASA scientific and technology demonstration payloads. These payloads and missions marked the first delivery of NASA instruments to operate from the lunar surface since the Apollo landings. One of these payloads is Lunar Node -1 (LN-1), a navigation beacon demonstration mission. The payload was designed and built by NASA’s Marshall Space Flight Center. The payload’s main goal was to demonstrate and provide insight into the use of lunar surface-based radio navigation aids. As part of the mission, LN-1 successfully conducted multiple one-way transmissions from the NOVA-C vehicle to Deep Space Network ground receivers using its onboard S-band transmitter, while being disciplined by an onboard Space Chip Scale Atomic Clock. LN-1 transmitted to DSN on an almost daily basis during transit to the moon, including two surface passes. The payload was originally plan to conduct 7-10 days of surface operation as an always-on beacon. These passes focused on evaluating two main navigation approaches: performance and stability of ranging using time-based transfer techniques on a cubesat size and grade platform, as well as one-way psuedonoise ranging approaches. To assess performance, the measurements were compared to independent navigation solutions using multiple approaches including: one-way Doppler tracking, two-way Doppler Tracking, and visual verification of the landing location provided by visual observations from orbital platforms. While the mission only conducted limited surface operations, the data provides some initial insight to performance form the lunar surface. These results are compared with initial ground-based testing as well as continued evaluation of the flight-space platform using multiple grades of oscillators for maintaining clock and frequency stability. These focus on the timing stability of platform in a deep-space environment as well variations in state determination. Given these insights, this paper provides additional description and evaluation of how this approach can be utilized as part of a broader lunar navigation architecture, such as being developed and deployed across multiple international space agencies. Analysis is provided to develop overall timing requirements and assessment of operational scenarios, such as orbit and surface location determination. In addition, the results support discussion as to how surface pseudolites could best be used within existing standard signal definitions, such as defined in the LunaNet Interoperability Specifications. This will consider concerns such as the near-/far- problem as well as operational considerations, including whether a beacon is better suited as two- or one-way ranging platform. The use cases are focused on how these psuedolites can provide additional coverage to augment and support planned operational coverage. For example, this analysis provides analysis of mid-latitude surface missions, where there may be limited geometry and availability of orbital relays. The results will show how these navigation psuedolites can fit within the developing architecture to provide additional robustness, capability, and support multiple use cases. Lastly, the paper will discuss challenges and next steps to be addressed in the implementation and testing of a follow-on payload and a continued path towards demonstration and integration of this capability into Lunar PNT architectures.

Evan J Anzalone↗

DOE OSTI2026

Prediction of non-intuitive metabolic targets with bayesian metabolic control analysis to improve 3-hydroxypropionic acid production in Aspergillus niger

Development of efficient bioconversion processes is limited by the ability to predictably improve metabolic flux. Here we deployed Bayesian Metabolic Control Analysis as a platform to integrate multi-omics data with metabolic modeling and evaluated its ability to predict genetic interventions that improve metabolic flux. Global Metabolomics and proteomics data was collected from 17 Aspergillus niger strains engineered to produce the platform biochemical 3-hydroxypropionic acid from which seven actional genetic interventions were predicted from significant flux control coefficients. Of the suggested genetic interventions, two were present within the intuitively designed strains used for training (malonic semialdehyde dehydrogenase and pyruvate carboxylase) while five predicted targets were present within non-intuitive areas of the metabolic network including 5-formyltetrahydrofolate deformylase and four mitochondrial enzymes, alcohol dehydrogenase, succinyl-CoA ligase, aspartate aminotransferase, and malate dehydrogenase. Six of the targets were validated in the highest performing 3-HP strain used for multi-omics data generation which contained a prior disruption of the highest scoring target malonic semialdehyde dehydrogenase. Predicted directional perturbation of five of the six tested targets significantly improved titer and rate of 3-HP production and two significantly improved yield. The greatest improvements were observed following disruption of the non-intuitive target succinyl-CoA ligase which increased titer by 39% and yield by 29% (to 20.4 g/L 3-HP and 0.31 g 3-HP/g glucose) over the strains used for training. This study demonstrates the utility of Bayesian Metabolic Control Analysis and highlights the ability to predict meaningful genetic targets in unexpected areas of metabolism to improve engineered strains for bioconversion.

3-hydroxypropionic acid↗

NASA NTRS1965

Dynamic testing.

Dynamic response of inertial platform systems examining comparison, growing exponential, Fourier analysis and exponential series methods of response evaluation

GYROSCOPIC STABILITY↗