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NASA NTRS2003

Wilbur and Orville Wright: A Reissue of a Chronology Commemorating the Hundredth Anniversary of the Birth of Orville Wright, August 19, 1871

During the year 2003, hundreds of events will mark the one-hundredth anniversary of the Wright brothers historic first flights at Kitty Hawk, North Carolina. The centennial year will witness exhibitions, lectures, television documentaries, films, air shows, flight recreations of Wright aircraft, the issuing of postage stamps and medals, the publication of dozens of new books and articles, and numerous other commemorative activities. One of these events, although not likely to make the evening news, is among the most important of all in terms of a lasting contribution to the observance of this ultimate aviation milestone: the reprinting of Arthur G. Renstrom WIlbur & Orville Wrght: A Chronology Commemorating the Hundredth Anniversary of the Birth of Orville Wright, August 19, 1871. Since its appearance in 1975, Wilbur end Orville Wright: A Chronology has become indispensable to students and authors concerned with the life and work of the famous brothers. No doubt every book on the subject published in the last quarter century, including three of my own, was written with this treasure close at hand. This volume is far more than a simple compilation of dates and facts. Renstrom was a master reference librarian and bibliographer with a passion for aviation and the Wright brothers. He brought his considerable research skills to bear on the topic, and the result is a richly detailed, ever-informative, often entertaining walk through the lives and achievements of these two extraordinary individuals. Renstrom was not content to offer a date with a one-line tidbit. His entries are brimming with information. This is a highly readable reference work that, believe it or not, can be enjoyably read from cover to cover. The project was clearly a labor of love by a talented professional. During most of the last twenty years, I have been privileged to be the curator of the 1903 Wright Flyer at the Smithsonian Institution s National Air and Space Museum. The position brings a steady stream of inquiries about the Wright airplane and the endlessly fascinating brothers who created it. I do not know how I would have done this job without Renstrom s superb volume on my bookshelf. It is the first place I go to check anything on the Wright brothers, and I typically find what I am looking for in its pages. Arthur Renstrom also published two other classic reference works on the Wright brothers: Wilbur & Orville Wright: A Bibliography Commemorating the Hundredth Anniversary of the Birth of Wilbur Wright, April 16, 1867, in 1968 (an updated revision was published by the National Aeronautics and Space Administration in 2002) and Wilbur & Orville Wright, Pictorial Materials: A Documentary Guide in 1982, completing a series of research tools for which there are few peers on any subject. He was also part of the team that produced the landmark two-volume compilation of the Wrights letters, notebooks, and diaries in 1953, The Papers of Wilbur and Orville Wright, edited by Marvin W. McFarland. Renstrom s contribution to the documentation and preservation of the Wright story is a lasting legacy that will serve researchers, students, and general enthusiasts for generations to come. In this busy, high-profile anniversary year, the reprinting of a nearly thirty-year-old reference book may seem a mundane and quiet contribution to the celebration surrounding the Wright brothers world-changing achievement, but it is perhaps one of the most important. The U.S. Centennial of Flight Commission and NASA are to be commended for their foresight.

Renstrom, Arthur George↗
NASA NTRS1999

Vortex Wakes of Subsonic Transport Aircraft

A historical overview will be presented of the research conducted on the structure and modification of the vortices generated by the lifting surfaces of subsonic transport aircraft. The seminar will describe the three areas of vortex research; namely, the magnitude of the hazard posed, efforts to reduce the hazard to an acceptable level, and efforts to develop a systematic means for avoiding vortex wakes. It is first pointed out that the characteristics of lift-generated vortices are related to the aerodynamic shapes that produce them and that various arrangements of surfaces can be used to produce different vortex structures. The largest portion of the research conducted to date has been directed at finding ways to reduce the hazard potential of lift-generated vortices shed by subsonic transport aircraft in the vicinity of airports during landing and takeoff operations. It is stressed that lift-generated vortex wakes are so complex that progress towards a solution requires application of a combined theoretical and experimental research program because either alone often leads to incorrect conclusions. It is concluded that a satisfactory aerodynamic solution to the wake-vortex problem at airports has not yet been found but a reduction in the impact of the wake-vortex hazard on airport capacity may become available in the foreseeable future through wake-vortex avoidance concepts currently under study. The material to be presented in this overview is drawn from articles published in aerospace journals that are available publicly.

Rossow, Vernon J.↗
NASA NTRS2016

Genelab: Scientific Partnerships and an Open-Access Database to Maximize Usage of Omics Data from Space Biology Experiments

NASA's mission includes expanding our understanding of biological systems to improve life on Earth and to enable long-duration human exploration of space. The GeneLab Data System (GLDS) is NASA's premier open-access omics data platform for biological experiments. GLDS houses standards-compliant, high-throughput sequencing and other omics data from spaceflight-relevant experiments. The GeneLab project at NASA-Ames Research Center is developing the database, and also partnering with spaceflight projects through sharing or augmentation of experiment samples to expand omics analyses on precious spaceflight samples. The partnerships ensure that the maximum amount of data is garnered from spaceflight experiments and made publically available as rapidly as possible via the GLDS. GLDS Version 1.0, went online in April 2015. Software updates and new data releases occur at least quarterly. As of October 2016, the GLDS contains 80 datasets and has search and download capabilities. Version 2.0 is slated for release in September of 2017 and will have expanded, integrated search capabilities leveraging other public omics databases (NCBI GEO, PRIDE, MG-RAST). Future versions in this multi-phase project will provide a collaborative platform for omics data analysis. Data from experiments that explore the biological effects of the spaceflight environment on a wide variety of model organisms are housed in the GLDS including data from rodents, invertebrates, plants and microbes. Human datasets are currently limited to those with anonymized data (e.g., from cultured cell lines). GeneLab ensures prompt release and open access to high-throughput genomics, transcriptomics, proteomics, and metabolomics data from spaceflight and ground-based simulations of microgravity, radiation or other space environment factors. The data are meticulously curated to assure that accurate experimental and sample processing metadata are included with each data set. GLDS download volumes indicate strong interest of the scientific community in these data. To date GeneLab has partnered with multiple experiments including two plant (Arabidopsis thaliana) experiments, two mice experiments, and several microbe experiments. GeneLab optimized protocols in the rodent partnerships for maximum yield of RNA, DNA and protein from tissues harvested and preserved during the SpaceX-4 mission, as well as from tissues from mice that were frozen intact during spaceflight and later dissected on the ground. Analysis of GeneLab data will contribute fundamental knowledge of how the space environment affects biological systems, and as well as yield terrestrial benefits resulting from mitigation strategies to prevent effects observed during exposure to space environments.

bioinformatics↗
NASA NTRS2016

GeneLab: Scientific Partnerships and an Open-Access Database to Maximize Usage of Omics Data from Space Biology Experiments

NASA's mission includes expanding our understanding of biological systems to improve life on Earth and to enable long-duration human exploration of space. The GeneLab Data System (GLDS) is NASAs premier open-access omics data platform for biological experiments. GLDS houses standards-compliant, high-throughput sequencing and other omics data from spaceflight-relevant experiments. The GeneLab project at NASA-Ames Research Center is developing the database, and also partnering with spaceflight projects through sharing or augmentation of experiment samples to expand omics analyses on precious spaceflight samples. The partnerships ensure that the maximum amount of data is garnered from spaceflight experiments and made publically available as rapidly as possible via the GLDS. GLDS Version 1.0, went online in April 2015. Software updates and new data releases occur at least quarterly. As of October 2016, the GLDS contains 80 datasets and has search and download capabilities. Version 2.0 is slated for release in September of 2017 and will have expanded, integrated search capabilities leveraging other public omics databases (NCBI GEO, PRIDE, MG-RAST). Future versions in this multi-phase project will provide a collaborative platform for omics data analysis. Data from experiments that explore the biological effects of the spaceflight environment on a wide variety of model organisms are housed in the GLDS including data from rodents, invertebrates, plants and microbes. Human datasets are currently limited to those with anonymized data (e.g., from cultured cell lines). GeneLab ensures prompt release and open access to high-throughput genomics, transcriptomics, proteomics, and metabolomics data from spaceflight and ground-based simulations of microgravity, radiation or other space environment factors. The data are meticulously curated to assure that accurate experimental and sample processing metadata are included with each data set. GLDS download volumes indicate strong interest of the scientific community in these data. To date GeneLab has partnered with multiple experiments including two plant (Arabidopsis thaliana) experiments, two mice experiments, and several microbe experiments. GeneLab optimized protocols in the rodent partnerships for maximum yield of RNA, DNA and protein from tissues harvested and preserved during the SpaceX-4 mission, as well as from tissues from mice that were frozen intact during spaceflight and later dissected on the ground. Analysis of GeneLab data will contribute fundamental knowledge of how the space environment affects biological systems, and as well as yield terrestrial benefits resulting from mitigation strategies to prevent effects observed during exposure to space environments.

spaceflight↗
DOE OSTI2020

Task 12 PV Sustainability - Life Cycle Inventories and Life Cycle Assessments of Photovoltaic Systems

Life Cycle Assessment (LCA) is a structured, comprehensive method of quantifying material- and energy-flows and their associated impacts in the life cycles of products (i.e., goods and services). One of the major goals of IEA PVPS Task 12 is to provide guidance on assuring consistency, balance, transparency and quality of LCA to enhance the credibility and reliability of the results. The current report presents the latest consensus life cycle inventories among the authors, PV LCA experts in North America, Europe, Asia and Australia. At this time consensus is limited to four technologies for which there are well-established and up-to-date life cycle inventory (LCI) data (mono- and multi-crystalline Si, CdTe, CIGS, as well as one emerging technology (perovskite silicon tandem). LCIs are necessary for LCA and the availability of such data is often the greatest barrier for conducting LCA. The Task 12 LCA experts have put great efforts in gathering and compiling the LCI data presented in this report. These include detailed inputs and outputs during manufacturing of cell, wafer, module, and balance-of-system (i.e., structural and electrical components) that were estimated from actual production and operation facilities. In addition, data are presented to enable analyses of various types of PV installations; these include operational data of rooftop and ground-mount PV systems and country-specific PV-mixes. The LCI datasets presented in this report are the latest that are available to the public describing the status in 2018 for crystalline Si (some manufacturing data from 2011 were not updated), 2015 and 2017-2018 for CdTe, 2010 for CIGS, 2010 for HCPV, and 2017 for perovskite silicon tandem technology.

14 SOLAR ENERGY↗
NASA NTRS2009

A Landsat-Based Assessment of Mobile Bay Land Use and Land Cover Change from 1974 to 2008

The Mobile Bay region has experienced noteworthy land use and land cover (LULC) change in the latter half of the 20th century. Accompanying this change has been urban expansion and a reduction of rural land uses. Much of this LULC change has reportedly occurred since the landfall of Hurricane Frederic in 1979. The Mobile Bay region provides great economic and ecologic benefits to the Nation, including important coastal habitat for a broad diversity of fisheries and wildlife. Regional urbanization threatens the estuary s water quality and aquatic-habitat dependent biota, including commercial fisheries and avian wildlife. Coastal conservation and urban land use planners require additional information on historical LULC change to support coastal habitat restoration and resiliency management efforts. This presentation discusses results of a Gulf of Mexico Application Pilot project that was conducted in 2008 to quantify and assess LULC change from 1974 to 2008. This project was led by NASA Stennis Space Center and involved multiple Gulf of Mexico Alliance (GOMA) partners, including the Mobile Bay National Estuary Program (NEP), the U.S. Army Corps of Engineers, the National Oceanic and Atmospheric Administration s (NOAA s) National Coastal Data Development Center (NCDDC), and the NOAA Coastal Services Center. Nine Landsat images were employed to compute LULC products because of their availability and suitability for the application. The project also used Landsat-based national LULC products, including coastal LULC products from NOAA s Coastal Change & Analysis Program (C-CAP), available at 5-year intervals since 1995. Our study was initiated in part because C-CAP LULC products were not available to assess the region s urbanization prior to 1995 and subsequent to post Hurricane Katrina in 2006. This project assessed LULC change across the 34-year time frame and at decadal and middecadal scales. The study area included the majority of Mobile and Baldwin counties that encompass Mobile Bay. In doing so, each date of Landsat data was classified using an end-user defined modified Anderson level 1 classification scheme. LULC classifications were refined using a decision rule approach in conjunction with available C-CAP products. Individual dates of LULC classifications were validated by image interpretation of stratified random locations on raw Landsat color composite imagery in combination with higher resolution remote sensing and in-situ reference data. The results indicate that during the 34-year study period, urban areas increased from 96,688 to 150,227 acres, representing a 55.37% increase, or 1.63% per annum. Most of the identified urban expansion results from conversion of rural forest and agriculture to urban cover types. Final LULC mapping and metadata products were produced for the entire study area as well as watersheds of concern within the study area. Final project products, including LULC trend information, were incorporated into the Mobile Bay NEP State of the Bay report. Products and metadata were transferred to NOAA NCDDC to allow free online accessibility and use by GOMA partners and by the public.

Spruce, Joseph↗
NASA NTRS2004

Collaborative Aerospace Research and Fellowship Program at NASA Glenn Research Center

During the summer of 2004, a 10-week activity for university faculty entitled the NASA-OAI Collaborative Aerospace Research and Fellowship Program (CFP) was conducted at the NASA Glenn Research Center in collaboration with the Ohio Aerospace Institute (OAI). This is a companion program to the highly successful NASA Faculty Fellowship Program and its predecessor, the NASA-ASEE Summer Faculty Fellowship Program that operated for 38 years at Glenn. The objectives of CFP parallel those of its companion, viz., (1) to further the professional knowledge of qualified engineering and science faculty,(2) to stimulate an exchange of ideas between teaching participants and employees of NASA, (3) to enrich and refresh the research and teaching activities of participants institutions, and (4) to contribute to the research objectives of Glenn. However, CFP, unlike the NASA program, permits faculty to be in residence for more than two summers and does not limit participation to United States citizens. Selected fellows spend 10 weeks at Glenn working on research problems in collaboration with NASA colleagues and participating in related activities of the NASA-ASEE program. This year's program began officially on June 1, 2004 and continued through August 7, 2004. Several fellows had program dates that differed from the official dates because university schedules vary and because some of the summer research projects warranted a time extension beyond the 10 weeks for satisfactory completion of the work. The stipend paid to the fellows was $1200 per week and a relocation allowance of $1000 was paid to those living outside a 50-mile radius of the Center. In post-program surveys from this and previous years, the faculty cited numerous instances where participation in the program has led to new courses, new research projects, new laboratory experiments, and grants from NASA to continue the work initiated during the summer. Many of the fellows mentioned amplifying material, both in undergraduate and graduate courses, on the basis of the summer s experience at Glenn. A number of 2004 fellows indicated that proposals to NASA will grow out of their summer research projects. In addition, some journal articles and NASA publications will result from this past summer s activities. Fellows from past summers continue to send reprints of articles that resulted from work initiated at Glenn. This report is intended primarily to summarize the research activities comprising the 2004 CFP Program at Glenn. Particular research studies include: 1) Development of an Imaging-Based, Computational Fluid Dynamics Tool to Assess Fluid Mechanics in Experimental Models that Simulate Blood Vessels; 2) Analysis of Nanomaterials Produced from Precursors; and 3) LEO Propagation Analysis Tool.

Heyward, Ann O.↗
DOE OSTI2024

M3SF-24LL010302052-Comprehensive Analysis of Radionuclide Interaction with Hydrothermally Altered Repository Materials

This progress report (Level 3 Milestone Number M3SF-24LL010302052) summarizes research conducted at Lawrence Livermore National Laboratory (LLNL) within the Crystalline Work Package Number SF-24LL01030205. The research is focused on actinide and radionuclide sequestration in hydrothermally altered repository materials. In FY24, we completed a rigorous analysis of Se sorption to iron oxide phases using our L-SCIE sorption database. This effort explicitly accounts for surface titration behavior of oxide surfaces that was the subject of a recently published manuscript (Han et al., 2023). With this in mind, our Se sorption analysis now yields a more robust workflow for developing self-consistent surface complexation modeling approaches that can be adapted to specific SCM conceptual and numerical approaches (i.e. non-electrostatic, diffuse layer, triple layer models). In late FY24, we plan to publish the results of our comprehensive surface complexation modeling of Se(IV) and Se(VI) sorption to iron oxide mineral phases and provide a path forward to developing robust radionuclide sorption models for use in performance assessment. In FY24, we also submitted a manuscript summarizing our approach to integrating radionuclide sorption and coprecipitation phenomena and evaluation of radionuclide partitioning values across a range of radionuclides relevant to performance assessment. We demonstrated our approach in detail using Se sorption and coprecipitation with iron oxide minerals as a test case. This manuscript was recently accepted for publication in Applied Geochemistry (Balboni et al., Accepted). We also continued experiments to identify radionuclide interaction with hydrothermally altered crystalline repository and backfill materials. Recent research performed at Los Alamos National Laboratory (LANL) and Sandia National Laboratory (SNL) has provided key insights regarding the hydrothermal alteration behavior of bentonite backfill in the presence of repository materials (steel, concrete, etc.). We are now examining how mineral alteration affects retardation behavior of a suite of radionuclides of interest to repository performance assessment. These experiments also allow us to test the predictive ability of our component additivity approach to surface complexation and ion exchange. Our guiding hypothesis is that a robust surface complexation/ion exchange model and associated database, developed using our L-SCIE approach, can effectively predict changes in radionuclide sorption behavior resulting from the hydrothermal alteration of mineralogy in a repository near field. A short update of results to date is presented below.

38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEA↗
NASA NTRS2015

NEAs: Phase Angle Dependence of Asteroid Class and Diameter from Observational Studies

We will discuss the results of a planned observation campaign of Near Earth Asteroids (NEAs), 1999 CU3, 2002 GM2, 2002 FG7, and 3691 Bede with instruments on the United Kingdom Infrared Telescope (UKIRT) from 15-Mar-2015 to 28-April 2015 UT. We will study the phase-angle dependence of the reflectance and thermal emission spectra. Recent publications reveal that the assignment of the asteroid class from visible and near-IR spectroscopy can change with phase angle for NEAs with silicate-bearing minerals on their surfaces (S-class asteroids) (Thomas et al. 2014, Icarus 228, 217; Sanchez et al. 2012 Icarus 220, 36). Only three of the larger NEAs have been measured at a dozen phase angles and the trends are not all the same, so there is not yet enough information to create a phase-angle correction. Also, the phase angle effect is not characterized well for the thermal emission including determination of the albedo and the thermal emission. The few NEAs were selected for our study amongst many possible targets based on being able to observe them through a wide range of phase angles, ranging from less than about 10 degrees to greater than 45 degrees over the constrained date range. The orbits of NEAs often generate short observing windows at phase angles higher than 45 deg (i.e., whizzing by Earth and/or close to dawn or dusk). Ultimately, lowering the uncertainty of the translation of asteroid class to meteorite analog and of albedo and size determinations are amongst our science goals. On a few specific nights, we plan to observe the 0.75-2.5 micron spectra with IRTF+SpeX for comparison with UKIRT data including 5-20 micron with UKIRT+UIST/Michelle to determine as best as possible the albedos. To ensure correct phasing of spectroscopic data, we augment with TRAPPIST-telescope light curves and R-band guider image data. Our observations will contribute to understanding single epoch mid-IR and near-IR measurements to obtain albedo, size and IR beaming parameters (the outcomes of thermal models) and asteroid spectral class.

phase-angle↗
DOE OSTI2025

Constraints on cosmology and baryonic feedback with joint analysis of Dark Energy Survey Year 3 lensing data and ACT DR6 thermal Sunyaev-Zel'dovich effect observations

We present a joint analysis of weak gravitational lensing (shear) data obtained from the first three years of observations by the Dark Energy Survey and thermal Sunyaev-Zel'dovich (tSZ) effect measurements from a combination of Atacama Cosmology Telescope (ACT) and Planck data. A combined analysis of shear (which traces the projected mass) with the tSZ effect (which traces the projected gas pressure) can jointly probe both the distribution of matter and the thermodynamic state of the gas, accounting for the correlated effects of baryonic feedback on both observables. We detect the shear$~\times~$tSZ cross-correlation at a 21$\sigma$ significance, the highest to date, after minimizing the bias from cosmic infrared background leakage in the tSZ map. By jointly modeling the small-scale shear auto-correlation and the shear$~\times~$tSZ cross-correlation, we obtain $S_8 = 0.811^{+0.015}_{-0.012}$ and $\Omega_{\rm m} = 0.263^{+0.023}_{-0.030}$, results consistent with primary CMB analyses from Planck and P-ACT. We find evidence for reduced thermal gas pressure in dark matter halos with masses $M < 10^{14} \, M_{\odot}/h$, supporting predictions of enhanced feedback from active galactic nuclei on gas thermodynamics. A comparison of the inferred matter power suppression reveals a $2-4\sigma$ tension with hydrodynamical simulations that implement mild baryonic feedback, as our constraints prefer a stronger suppression. Finally, we investigate biases from cosmic infrared background leakage in the tSZ-shear cross-correlation measurements, employing mitigation techniques to ensure a robust inference. Our code is publicly available on GitHub.

Pandey, S. [Johns Hopkins U.; Columbia U.] (ORCID:↗
NASA NTRS2015

New York City Panel on Climate Change 2015 Report Introduction

The climate of the New York City metropolitan region is changing annual temperatures are hotter, heavy downpours are increasingly frequent, and the sea is rising. These trends, which are also occurring in many parts of the world, are projected to continue and even worsen in the coming decades because of higher concentrations of greenhouse gases in the atmosphere caused by burning of fossil fuels and clearing of forests for agriculture. These changing climate hazards increase the risks for the people, economy, and infrastructure of New York City. As was demonstrated by Hurricane Sandy, coastal and low-lying areas, the elderly and very young, and lower-income neighborhoods are highly vulnerable. In response to these climate challenges, New York City is developing a broad range of climate resiliency policies and programs, as well as the knowledge base to support them. The knowledge base includes up-to-date climate, sea level rise, and coastal flooding projections; a Climate Resiliency Indicators and Monitoring System; and resiliency studies. A special attribute of the New York City response to these challenges is the recognition that both the knowledge base and the programs and policies it supports need to evolve through time as climate risks unfold in the coming decades. In early September 2012, just weeks before Hurricane Sandy hit, the New York City Council passed Local Law 42 that established the New York City Panel on Climate Change (NPCC) as an ongoing body serving the City of New York. The NPCC is required to meet at least twice each calendar year to review recent scientific data on climate change and its potential impacts, and to make recommendations on climate projections for the coming decades to the end of the century. These projections are due within one year of the publication of the Intergovernmental Panel on Climate Change Assessment Reports (http:www.ipcc.ch), or at least every three years. The NPCC also advises the Mayor's Office of Sustainability and the Mayor's Office of Recovery and Resiliency (ORR) on the development of a community- or borough-level communications strategy intended to ensure that the public is informed about the findings of the panel, including the creation of a summary of the climate change projections for dissemination to city residents.

hurricanes↗
NASA NTRS2020

A Systems Analysis Approach to Understanding the Physiological Adaptation to Spaceflight

This book is a summary of interdisciplinary research (physiology, space medicine, engineering, computer science, mathematics) that spans two decades (1972-1992). The research was an attempt to use systems analysis, mathematical modeling, computer simulations, and database systems to integrate the biomedical spaceflight data that was being collected during this period. The goal of the effort was to achieve a better understanding of the human physiological response to short-term and long-term space travel. The activity was primarily devoted to analyzing the biomedical results of Skylab (1973-74), a series of three space missions which is still ranked as the most comprehensive of all long-term biomedical space studies to date. This work was begun as a coordinated effort between the National Aeronautics and Space Administration (Johnson Space Center) and the General Electric Company’s Space Division (Houston, TX). It was the intent that this multidisciplined, integrative approach could reveal aspects of the then-new science of microgravity adaptation that were not obvious by adhering to the traditional methodology of examining each organ system in isolation. Some joint work with the Russians, including the Apollo-Soyez test project and a joint bedrest study was also supported during this period. In the 1980’s the systems analysis group’s effort was redirected to support the science management of human and animal experiments on the Space Shuttle. A few examples from this era are also included in the book. Parts of this work have been published elsewhere, presented at technical meetings, and documented in reports with limited distribution. These publications will be referenced throughout the text and the interested reader is advised to use these as resource material where additional details are desired. The intent of this book is not to reproduce these documents but rather to present a coherent view of the integrative analysis under one cover. This volume contains the first detailed publication (other than in internal reports) of an extensive metabolic balance analysis of Skylab data, the development and validation of the “Whole-Body Algorithm,” and simulation studies of diverse hypogravic environments. An analysis of cardiovascular deconditioning and a description of the calcium regulatory model are also new. A long period has passed between the completion of the main body of work represented in this book and its publication in this form. It was inevitable that new research efforts would lead to developments related to the spaceflight problems addressed and thereby make some of our biomedical conclusions obsolete. Although in some cases reference to more recent work have been included, for the most part this book should be considered an historical summary demonstrating the approach and utility of systems analysis and computer modeling in the NASA Life Sciences program at the time the studies were conducted.

Leonard, Joel I.↗
DOE OSTI2024

Indicators of Global Climate Change 2023: annual update of key indicators of the state of the climate system and human influence

Intergovernmental Panel on Climate Change (IPCC) assessments are the trusted source of scientific evidence for climate negotiations taking place under the United Nations Framework Convention on Climate Change (UNFCCC). Evidence-based decision-making needs to be informed by up-to-date and timely information on key indicators of the state of the climate system and of the human influence on the global climate system. However, successive IPCC reports are published at intervals of 5–10 years, creating potential for an information gap between report cycles. We follow methods as close as possible to those used in the IPCC Sixth Assessment Report (AR6) Working Group One (WGI) report. We compile monitoring datasets to produce estimates for key climate indicators related to forcing of the climate system: emissions of greenhouse gases and short-lived climate forcers, greenhouse gas concentrations, radiative forcing, the Earth's energy imbalance, surface temperature changes, warming attributed to human activities, the remaining carbon budget, and estimates of global temperature extremes. The purpose of this effort, grounded in an open-data, open-science approach, is to make annually updated reliable global climate indicators available in the public domain. As they are traceable to IPCC report methods, they can be trusted by all parties involved in UNFCCC negotiations and help convey wider understanding of the latest knowledge of the climate system and its direction of travel. The indicators show that, for the 2014–2023 decade average, observed warming was 1.19 [1.06 to 1.30] °C, of which 1.19 [1.0 to 1.4] °C was human-induced. For the single-year average, human-induced warming reached 1.31 [1.1 to 1.7] °C in 2023 relative to 1850–1900. The best estimate is below the 2023-observed warming record of 1.43 [1.32 to 1.53] °C, indicating a substantial contribution of internal variability in the 2023 record. Human-induced warming has been increasing at a rate that is unprecedented in the instrumental record, reaching 0.26 [0.2–0.4] °C per decade over 2014–2023. This high rate of warming is caused by a combination of net greenhouse gas emissions being at a persistent high of 53±5.4 Gt CO 2 e yr -1 over the last decade, as well as reductions in the strength of aerosol cooling. Despite this, there is evidence that the rate of increase in CO 2 emissions over the last decade has slowed compared to the 2000s, and depending on societal choices, a continued series of these annual updates over the critical 2020s decade could track a change of direction for some of the indicators presented here.

54 ENVIRONMENTAL SCIENCES↗
NASA NTRS2006

Progress and Plans in Support of the Polar Community

Feedback provided by the Antarctic community has proven instrumental in positively influencing the direction of the GCMD's development. For example, in response to requests for a stand alone metadata authoring tool, a new shareable software package called docBUILDER solo will be released to the public in March 2006. This tool permits researchers to document their data during experiments and observational periods in the field. The international polar community has also played a key role in encouraging support for the foreign language character set in the metadata display and tools (10% of the records in the AMD hold foreign characters). In the upcoming release, the full ISO character set, which also includes mathematical symbols, will be supported. Additional upgrades include the ability for users to search for data sets based on pre-selected temporal and spatial resolution ranges. Data providers are strongly encouraged to populate the resolution fields for their data sets, although these fields are not currently required. In prior versions, browser incompatibilities often resulted in unreliable performance for users attempting to initiate a spatial search using a map based on Java applet technology. The GCMD will offer an integrated Google map and date search, replacing the applet technology and enhancing the geospatial and temporal searches. It is estimated that 30% of the records in the AMD have direct access to data. A growing number of these records can be accessed through data service links. Related data services are therefore becoming valuable assets in facilitating the use and visualization of data. Users will gain the ability to refine services using the same options as those available for data set searches. Data providers are encouraged to describe available data-related services through the directory. Future plans include offering web services through a SOAP interface and extending semantic queries for the polar regions through the use of ontologies. The Open Archives Initiative's (OAI) Protocol for Metadata Harvesting (PMH) has been successfully tested with several organizations and appears to be a prime candidate for sharing metadata within the community. The GCMD anticipates contributing to the design of the data management system for the International Polar Year and to the ongoing efforts in the years to come. Further enhancements will be discussed at the meeting.

Olsen, Lola M.↗
DOE OSTI2022

Machine Learning of All Mycobacterium tuberculosis H37Rv RNA-seq Data Reveals a Structured Interplay between Metabolism, Stress Response, and Infection

Mycobacterium tuberculosis is one of the most consequential human bacterial pathogens, posing a serious challenge to 21st century medicine. A key feature of its pathogenicity is its ability to adapt its transcriptional response to environmental stresses through its transcriptional regulatory network (TRN). While many studies have sought to characterize specific portions of the M. tuberculosis TRN, and some studies have performed system-level analysis, few have been able to provide a network-based model of the TRN that also provides the relative shifts in transcriptional regulator activity triggered by changing environments. Here, we compiled a compendium of nearly 650 publicly available, high quality M. tuberculosis RNA-sequencing data sets and applied an unsupervised machine learning method to obtain a quantitative, top-down TRN. It consists of 80 independently modulated gene sets known as “iModulons,” 41 of which correspond to known regulons. These iModulons explain 61% of the variance in the organism’s transcriptional response. We show that iModulons (i) reveal the function of poorly characterized regulons, (ii) describe the transcriptional shifts that occur during environmental changes such as shifting carbon sources, oxidative stress, and infection events, and (iii) identify intrinsic clusters of regulons that link several important metabolic systems, including lipid, cholesterol, and sulfur metabolism. This transcriptome-wide analysis of the M. tuberculosis TRN informs future research on effective ways to study and manipulate its transcriptional regulation and presents a knowledge-enhanced database of all published high-quality RNA-seq data for this organism to date.

59 BASIC BIOLOGICAL SCIENCES↗
NASA NTRS2018

NASA Earth Science Data Rescue Efforts

Historically, at the end of a NASA mission, earth and space science data were stored at NASA's National Space Science Data Center (NSSDC). The original data archive consisted of both magnetic tapes and film media. As data storage technology improved, data from later missions were stored on disks and platters and higher capacity magnetic media for online accessibility. To conserve physical space at NASA archive sites and to meet disaster recovery guidelines, historical data originally stored on magnetic tapes and film were moved to the Federal Archives and Record Center (FRC) as a temporary holding area until its long-term value was determined by NASA. All records at the FRC are controlled by the NASA Records Retention Schedule (NRRS) which determines the disposal date for each record. On that date, responsible NASA parties are notified that all scheduled records should be reviewed and assessed to determine if they continue to hold significant historical, scientific or administrative value. For Earth Science data records being held at FRC, the Earth Science Data and Information System (ESDIS) Project office is the party responsible for making the value assessment that determines which records warrant preservation and which are ready for proper disposal according to NASA guidelines. Once the data's long-term value is determined, ESDIS takes definitive steps to preserve this data for future discovery and access. Deteriorating media containing historic data of value are recalled from FRC and brought back to ESDIS. Through a tedious, laborious process, digital data are recovered and restored to modern formats with improved metadata and documentation to aid discovery. The restored digital products are then incorporated into our modern online archive, and made immediately accessible to the public. In this paper, we will discuss how we identify data-at-risk, ways to minimize data loss, how we plan for recovery, how we delegate recovery activities to our archive facilities, and how we make recovered data more accessible.

Data Systems; Social and Information sciences↗
NASA NTRS2013

Closeout Report for the Refractory Metal Accelerated Heat Pipe Life Test Activity

With the selection of a gas-cooled reactor, this heat pipe accelerated life test activity was closed out and its resources redirected. The scope of this project was to establish the long-term aging effects on Mo-44.5%Re sodium heat pipes when subjected to space reactor temperature and mass fluences. To date, investigators have demonstrated heat pipe life tests of alkali metal systems up to .50,000 hours. Unfortunately, resources have not been available to examine the effect of temperature, mass fluence, or impurity level on corrosion or to conduct post-test forensic examination of heat pipes. The key objective of this effort was to establish a cost/time effective method to systematically test alkali metal heat pipes with both practical and theoretical benefits. During execution of the project, a heat pipe design was established, a majority of the laboratory test equipment systems specified, and operating and test procedures developed. Procurements for the heat pipe units and all major test components were underway at the time the stop work order was issued. An extremely important outcome was the successful fabrication of an annular wick from Mo-5%Re screen (the single, most difficult component to manufacture) using a hot isostatic pressing technique. This Technical Publication (TP) includes specifics regarding the heat pipe calorimeter water-cooling system, vendor design for the radio frequency heating system, possible alternative calorimeter designs, and progress on the vanadium equilibration technique. The methods provided in this TP and preceding project documentation would serve as a good starting point to rapidly implement an accelerated life test. Relevant test data can become available within months, not years, and destructive examination of the first life test heat pipe might begin within 6 months of test initiation. Final conclusions could be drawn in less than a quarter of the mission duration for a long-lived, fission-powered, deep space probe.

Martin, J.↗
NASA NTRS2017

Clast Selection and Metallographic Cooling Rates: Initial Results on Type 1A and 2A Mesosiderites

We initiated a comprehensive study on selected clasts and metal of mesosiderites using SEM, electron microprobe and the complete suite of noble gases. Here we report initial results on the petrography of selected clasts and metallographic cooling rates using the central Ni method used in sev-eral publications. We focus on the approach of selecting grains in least recrystallized mesosiderites. Hence, especially (lithic) clasts in type 1A, 1B, 2A and 2B are the first choice. They provide highest primitive-ness and least annealing/metamorphism. All grains selected should be in close proximity to each other. Lithic clasts in mesosiderites are of high interest be-cause of their igneous texture and similarity to eucrites and howardite petrography. We find pyrox-enes (px) and plagioclase (plag) attached to each other which implies a common formation history. It will be interesting to see differences and similarities in their noble gas inventory (CRE ages, trapped components and closure temperature). In addition, we will investi-gate variations of the lithic clasts toward similar grains in the thick sections which are not igneous. Plag grains are the best bases for noble gas measurements con-cerning He to Ar and Ar-Ar dating since it delivers im-portant target elements. We focus on plag grains in close contact to olivine (olv) / px grains to assess weth-er both grains show noble gas patterns being similar or different. Phosphate grains are suitable for Kr and Xe measurements since they yield REE abundances (tar-get elements).

Mesosiderites↗