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DOE OSTI2015

Mass assembly of stellar systems and their evolution with the SMA (MASSES). multiplicity and the physical environment in L1448N

We present continuum and molecular line observations at 230 and 345 GHz from the Submillimeter Array (SMA) toward three protostars in the Perseus L1448N region. The data are from the large project “Mass Assembly of Stellar Systems and their Evolution with the SMA.” Three dust continuum sources, Source B, Source NW, and Source A, are detected at both frequencies. These sources have corresponding emission peaks in C{sup 18}O (J=2→1), {sup 13}CO (J=2→1), and HCO{sup +} (J=4→3), and have offsets with N{sub 2}D{sup +} (J=3→2) peaks. High angular resolution data from a complementary continuum survey with the Karl G. Jansky Very Large Array show that Source B is associated with three 8 mm continuum objects, Source NW with two, and Source A remains single. These results suggest that multiplicity in L1448N exists at different spatial scales from a few thousand AU to <100 AU. Velocity gradients in each source obtained from two-dimensional fits to the SMA C{sup 18}O emission are found to be perpendicular to within 20° of the outflow directions as revealed by {sup 12}CO (J=2→1). We have observed that Sources B and NW with multiplicity have higher densities than Source A without multiplicity. This suggests that thermal Jeans fragmentation can be relevant in the fragmentation process. However, we have not observed a difference in the ratio between rotational and gravitational energy between sources with and without multiplicity. We also have not observed a trend between non-thermal velocity dispersions and the level of fragmentation. Our study has provided the first direct and comprehensive comparison between multiplicity and core properties in low-mass protostars, although based on small number statistics.

79 ASTRONOMY AND ASTROPHYSICS↗

DOE OSTI2016

Improvements in simulation of multiple scattering effects in ATLAS fast simulation

Fast ATLAS Tracking Simulation (Fatras) package was verified on single layer geometry with respect to full simulation with GEANT4. Fatras hadronic interactions and multiple scattering simulation were studied in comparison with GEANT4. Disagreement was found in multiple scattering distributions of primary charged particles (μ, π, e). A new model for multiple scattering simulation was implemented in Fatras. The model was based on R. Frühwirth’s mixture models. New model was tested on single layer geometry and a good agreement with GEANT4 was achieved. Also a comparison of reconstructed tracks’ parameters was performed for Inner Detector geometry, and Fatras with new multiple scattering model proved to have better agreement with GEANT4. New model of multiple scattering was added as a part of Fatras package in the development release of ATLAS software—ATHENA.

74 ATOMIC AND MOLECULAR PHYSICS↗

DOE OSTI2015

Multiplicity Counting

This set of slides begins by giving background and a review of neutron counting; three attributes of a verification item are discussed: 240 Pu eff mass; α, the ratio of (α,n) neutrons to spontaneous fission neutrons; and leakage multiplication. It then takes up neutron detector systems – theory & concepts (coincidence counting, moderation, die-away time); detector systems – some important details (deadtime, corrections); introduction to multiplicity counting; multiplicity electronics and example distributions; singles, doubles, and triples from measured multiplicity distributions; and the point model: multiplicity mathematics.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

DOE OSTI2023

Measurements of J/ ψ Production vs. Event Multiplicity in Forward Rapidity in p + p Collisions in the PHENIX Experiment

J / Ψ, a charmonium bound state made of a charm and an anti-charm quark, was discovered in the 1970s and confirmed the quark model. Because the mass of charm quarks is significantly above the quantum chromodynamics (QCD) scale Λ QCD , charmonia are considered excellent probes to test perturbative quantum chromodynamics (pQCD) calculations. In recent decades, they have been studied extensively at different high-energy colliders. However, their production mechanisms, which involve multiple scales, are still not very well understood. Recently, in high-multiplicity p + p collisions at RHIC and at the LHC, a significant enhancement of J / Ψ production yield has been observed, which suggests a strong contribution of multi-parton interaction (MPI). This is different from the traditional pQCD picture, where charm quark pairs are produced from a single hard scattering between partons in p + p collisions. In this work, we will report the J / Ψ normalized production yield as a function of normalized charged particle multiplicity over a board range of rapidity and event multiplicity in the J / Ψ → μ + μ – channel with PHENIX Run 15 p + p data at $\sqrt s$ =200 GeV. The results are compared with PYTHIA 8 simulations with the MPI option turned on and off. Finally, the outlooks of J / Ψ in p + Au and Au + p collisions, along with color glass condensate (CGC) predictions and the multiplicity-dependent Ψ(2S) /J / Ψ ratio in p + p data, will be briefly discussed.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

DOE OSTI2016

Comparison of the Performance of Various Correlated Fission Multiplicity Monte Carlo Codes

When measuring special nuclear material for a large array of national security needs, it is often important to accurately predict outcomes of the physical experiment using Monte Carlo radiation transport codes. Historically, radiation transport codes have uncorrelated fission emissions. In reality, both spontaneous and induced fissions release particles that are correlated in time, energy, and multiplicity. This work investigates the performance of various current Monte Carlo codes that take into account the correlated physics of fission neutrons. Only fission neutrons are of interest and the physics of gamma production in fission is ignored. Because of their large impact on correlated neutron results, underlying fission neutron multiplicity distributions utilized by the different codes are also compared. The codes currently being compared include MCNP{sup R}6, MCNP{sup R}6/FREYA, and MCNPX-PoliMi. By default, MCNP{sup R}6 uses a bounded integer treatment to sample the number of neutrons emitted from each fission event. The FMULT card, an optional input in MCNP that allows for user definition of spontaneous and induced fission parameters, can be utilized to call either built-in or user-specified multiplicities to replace the bounded integer treatment. Similarly, MCNPX-PoliMi utilizes one of a few different built-in multiplicity sets. MCNPX-PoliMi also models the multiplicity dependence of emitted neutron energy in spontaneous fission. It is possible to use an anisotropic model for emitted fission neutrons in MCNPXPoliMi, but this option was not used. For MCNP{sup R}6/FREYA, the FREYA fission event generator determines the number of particles emitted for each fission event and gives the results to MCNP{sup R}6 for transport. The fission event generator uses fission fragment mass and kinetic energy distributions, unbounded statistical evaporation models, and conservation of energy and momentum to generate the number, energy, and direction of neutrons released by each fission event. (authors)

73 NUCLEAR PHYSICS AND RADIATION PHYSICS↗

DOE OSTI2025

Multiple Twinning in Nacre and Aragonite

Twinning occurs when two crystals share a coherent interface along which their lattices are mirror symmetric. Here, twinning is investigated in biogenic and geologic aragonite (CaCO 3 ) in columnar nacre from the red abalone Haliotis rufescens, sheet nacre from the black-lip pearl oyster Pinctada margaritifera, and geologic aragonite. All samples exhibit the expected single (110) twins, characterized by a 116.2° rotation of the aragonite a-axis. Surprisingly, multiple twins—double, triple, quadruple—are also observed, each involving successive 116.2° rotations of the a-axis around the c-axis. Multiple twinning is concomitant but distinct from the well-known cyclic twinning of aragonite. Multiple twinning is most prevalent in columnar nacre, reaching up to quadruple twins, most frequently occurring between nacre tablets in the same column, whereas sheet nacre and geologic aragonite exhibit up to triple twins. The frequency of twins decreases with increasing twin multiple, consistent with a physical rather than biological origin. This interpretation is supported by observations in geologic aragonite and by simulations of columnar nacre growth, which incorporate only nucleation rate, growth rate, and basic geometric constraints, yet they reproduce the observed twinning behavior in columnar nacre, reinforcing the conclusion that multiple twinning arises from physical growth mechanisms.

Schmidt, Connor A. [Univ. of Wisconsin, Madison, W↗

DOE OSTI2011

Charged particle multiplicities in pp interactions at sqrt(s) = 0.9, 2.36, and 7 TeV

Measurements of primary charged hadron multiplicity distributions are presented for non-single-diffractive events in proton-proton collisions at centre-of-mass energies of sqrt(s) = 0.9, 2.36, and 7 TeV, in five pseudorapidity ranges from |eta|<0.5 to |eta|<2.4. The data were collected with the minimum-bias trigger of the CMS experiment during the LHC commissioning runs in 2009 and the 7 TeV run in 2010. The multiplicity distribution at sqrt(s) = 0.9 TeV is in agreement with previous measurements. At higher energies the increase of the mean multiplicity with sqrt(s) is underestimated by most event generators. The average transverse momentum as a function of the multiplicity is also presented. The measurement of higher-order moments of the multiplicity distribution confirms the violation of Koba-Nielsen-Olesen scaling that has been observed at lower energies.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

DOE OSTI2015

Forward-backward multiplicity correlations in pp collisions at $\sqrt{s}$ = 0.9, 2.76 and 7 TeV

The strength of forward-backward (FB) multiplicity correlations is measured by the ALICE detector in proton-proton (pp) collisions at $\sqrt{s}$ = 0.9, 2.76 and 7 TeV. The measurement is performed in the central pseudorapidity region (|η| < 0.8) for the transverse momentum p T > 0.3 GeV/c. Two separate pseudorapidity windows of width ($\delta$η) ranging from 0.2 to 0.8 are chosen symmetrically around η = 0. The multiplicity correlation strength (b corr ) is studied as a function of the pseudorapidity gap (η gap ) between the two windows as well as the width of these windows. The correlation strength is found to decrease with increasing η gap and shows a non-linear increase with $\delta$η. A sizable increase of the correlation strength with the collision energy, which cannot be explained exclusively by the increase of the mean multiplicity inside the windows, is observed. The correlation coefficient is also measured for multiplicities in different configurations of two azimuthal sectors selected within the symmetric FB η-windows. Two different contributions, the short-range (SR) and the long-range (LR), are observed. The energy dependence of b corr is found to be weak for the SR component while it is strong for the LR component. Moreover, the correlation coefficient is studied for particles belonging to various transverse momentum intervals chosen to have the same mean multiplicity. Both SR and LR contributions to b corr are found to increase with p T in this case. Results are compared to PYTHIA and PHOJET event generators and to a string-based phenomenological model. In conclusion, the observed dependencies of b corr add new constraints on phenomenological models.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗

DOE OSTI2025

Search for jet quenching with dijets from high-multiplicity pPb collisions at $\sqrt{s_{NN}}$ = 8.16 TeV

The first measurement of the dijet transverse momentum balance xj in proton-lead (pPb) collisions at a nucleon-nucleon center-of-mass energy of $\sqrt{s_{NN}}$ = 8.16 TeV is presented. The xj observable, defined as the ratio of the subleading over leading jet transverse momentum in a dijet pair, is used to search for jet quenching effects. The data, corresponding to an integrated luminosity of 174.6 nb −1 , were collected with the CMS detector in 2016. The x j distributions and their average values are studied as functions of the charged-particle multiplicity of the events and for various dijet rapidity selections. The latter enables probing hard scattering of partons carrying distinct nucleon momentum fractions x in the proton- and lead-going directions. The former, aided by the high-multiplicity triggers, allows probing for potential jet quenching effects in high-multiplicity events (with up to 400 charged particles), for which collective phenomena consistent with quark-gluon plasma (QGP) droplet formation were previously observed. The ratios of x j distributions for high- to low-multiplicity events are used to quantify the possible medium effects. These ratios are consistent with simulations of the hard-scattering process that do not include QGP production. These measurements set an upper limit on medium-induced energy loss of the subleading jet of 1.26% of its transverse momentum at the 90% confidence level in high multiplicity pPb events.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

DOE OSTI2023

Inclusive and multiplicity dependent production of electrons from heavy-flavour hadron decays in pp and p-Pb collisions

Measurements of the production of electrons from heavy-flavour hadron decays in pp collisions at $\sqrt{s}$ = 13 TeV at midrapidity with the ALICE detector are presented down to a transverse momentum (p T ) of 0.2 GeV/c and up to p T = 35 GeV/c, which is the largest momentum range probed for inclusive electron measurements in ALICE. In p-Pb collisions, the production cross section and the nuclear modification factor of electrons from heavy-flavour hadron decays are measured in the p T range 0.5 < p T < 26 GeV/c at $\sqrt{s_{NN}}$= 8.16 TeV. The nuclear modification factor is found to be consistent with unity within the statistical and systematic uncertainties. In both collision systems, first measurements of the yields of electrons from heavy-flavour hadron decays in different multiplicity intervals normalised to the multiplicity-integrated yield (self-normalised yield) at midrapidity are reported as a function of the self-normalised charged-particle multiplicity estimated at midrapidity. The self-normalised yields in pp and p-Pb collisions grow faster than linear with the self-normalised multiplicity. A strong p T dependence is observed in pp collisions, where the yield of high-p T electrons increases faster as a function of multiplicity than the one of low-p T electrons. The measurement in p-Pb collisions shows no p T dependence within uncertainties. The self-normalised yields in pp and p-Pb collisions are compared with measurements of other heavy-flavour, light-flavour, and strange particles, and with Monte Carlo simulations.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

DOE OSTI2024

Investigating strangeness enhancement with multiplicity in pp collisions using angular correlations

A study of strange hadron production associated with hard scattering processes and with the underlying event is conducted to investigate the origin of the enhanced production of strange hadrons in small collision systems characterised by large charged-particle multiplicities. For this purpose, the production of the single-strange meson ${\textrm{K}}_{\textrm{S}}^0$ and the double-strange baryon Ξ ± is measured, in each event, in the azimuthal direction of the highest-p T particle (“trigger” particle), related to hard scattering processes, and in the direction transverse to it in azimuth, associated with the underlying event, in pp collisions at $\sqrt{s}$ = 5.02 TeV and $\sqrt{s}$ = 13 TeV using the ALICE detector at the LHC. The per-trigger yields of ${\textrm{K}}_{\textrm{S}}^0$ and Ξ ± are dominated by the transverse-to-leading production (i.e., in the direction transverse to the trigger particle), whose contribution relative to the toward-leading production is observed to increase with the event charged-particle multiplicity. The transverse-to-leading and the toward-leading Ξ ± /${\textrm{K}}_{\textrm{S}}^0$ yield ratios increase with the multiplicity of charged particles, suggesting that strangeness enhancement with multiplicity is associated with both hard scattering processes and the underlying event. The relative production of Ξ ± with respect to ${\textrm{K}}_{\textrm{S}}^0$ is higher in transverse-to-leading processes over the whole multiplicity interval covered by the measurement. The ${\textrm{K}}_{\textrm{S}}^0$ and Ξ ± per-trigger yields and yield ratios are compared with predictions of three different phenomenological models, namely Pythia8.2 with the Monash tune, Pythia8.2 with ropes and EPOS LHC. The comparison shows that none of them can quantitatively describe either the transverse-to-leading or the toward-leading yields of ${\textrm{K}}_{\textrm{S}}^0$ and Ξ ± .

hadron-hadron scattering↗

DOE OSTI2015

Simultaneous Multiple Preoperative Localizations of Small Pulmonary Lesions Using a Short Hook Wire and Suture System

PurposeThe aim of the study was to retrospectively evaluate simultaneous multiple hook wire placement outcomes before video-assisted thoracoscopic surgery (VATS).Materials and MethodsThirty-eight procedures were performed on 35 patients (13 men and 22 women; mean age, 59.9 years) with 80 lung lesions (mean diameter 7.9 mm) who underwent simultaneous multiple hook wire placements for preoperative localizations. The primary endpoints were technical success, complications, procedure duration, and VATS outcome; secondary endpoints included comparisons between technical success rates, complication rates, and procedure durations of the 238 single-placement procedures performed. Complications were also evaluated.ResultsIn 35 procedures including 74 lesions, multiple hook wire placements were technically successful; in the remaining three procedures, the second target placement was aborted because of massive pneumothorax after the first placement. Although complications occurred in 34 procedures, no grade 3 or above adverse event was observed. The mean procedure duration was 36.4 ± 11.8 min. Three hook wires dislodged during patient transport to the surgical suite. Seventy-four successfully marked lesions were resected. Six lesions without hook wires were successfully resected after detection by palpation with an additional mini-thoracotomy or using subtle pleural changes as a guide. The complication rates and procedure durations of multiple-placement procedures were significantly higher (P = 0.04) and longer (P < 0.001) than those in the single-placement group, respectively, while the technical success rate was not significantly different (P = 0.051).ConclusionsSimultaneous multiple hook wire placements before VATS were clinically feasible, but increased the complication rate and lengthened the procedure time.

62 RADIOLOGY AND NUCLEAR MEDICINE↗

DOE OSTI2018

Upscaling permeability for three-dimensional fractured porous rocks with the multiple boundary method

Upscaling permeability of grid blocks is crucial for groundwater models. A novel upscaling method for three-dimensional fractured porous rocks is presented. The objective of the study was to compare this method with the commonly used Oda upscaling method and the volume averaging method. First, the multiple boundary method and its computational framework were defined for three-dimensional stochastic fracture networks. Then, the different upscaling methods were compared for a set of rotated fractures, for tortuous fractures, and for two discrete fracture networks. The results computed by the multiple boundary method are comparable with those of the other two methods and fit best the analytical solution for a set of rotated fractures. The errors in flow rate of the equivalent fracture model decrease when using the multiple boundary method. Furthermore, the errors of the equivalent fracture models increase from well-connected fracture networks to poorly connected ones. Finally, the diagonal components of the equivalent permeability tensors tend to follow a normal or log-normal distribution for the well-connected fracture network model with infinite fracture size. By contrast, they exhibit a power-law distribution for the poorly connected fracture network with multiple scale fractures. The study demonstrates the accuracy and the flexibility of the multiple boundary upscaling concept. This makes it attractive for being incorporated into any existing flow-based upscaling procedures, which helps in reducing the uncertainty of groundwater models.

58 GEOSCIENCES↗

DOE OSTI2014

EEN regulates the proliferation and survival of multiple myeloma cells by potentiating IGF-1 secretion

Highlights: • Levels of EEN expression paralleled with the rate of cell proliferation. • EEN was involved in the proliferation and survival of multiple myeloma (MM) cells. • EEN regulated the activity of IGF-1-Akt/mTOR pathway. • EEN regulated proliferation and survival of MM cells by enhancing IGF-1 secretion. - Abstract: The molecular mechanisms of multiple myeloma are not well defined. EEN is an endocytosis-regulating molecule. Here we report that EEN regulates the proliferation and survival of multiple myeloma cells, by regulating IGF-1 secretion. In the present study, we observed that EEN expression paralleled with cell proliferation, EEN accelerated cell proliferation, facilitated cell cycle transition from G1 to S phase by regulating cyclin-dependent kinases (CDKs) pathway, and delayed cell apoptosis via Bcl2/Bax-mitochondrial pathway. Mechanistically, we found that EEN was indispensable for insulin-like growth factor-1 (IGF-1) secretion and the activation of protein kinase B-mammalian target of rapamycin (Akt-mTOR) pathway. Exogenous IGF-1 overcame the phenotype of EEN depletion, while IGF-1 neutralization overcame that of EEN over-expression. Collectively, these data suggest that EEN may play a pivotal role in excessive cell proliferation and insufficient cell apoptosis of bone marrow plasma cells in multiple myeloma. Therefore, EEN may represent a potential diagnostic marker or therapeutic target for multiple myeloma.

60 APPLIED LIFE SCIENCES↗

DOE OSTI2016

Forward-backward multiplicity correlations in pp, p+Pb and Pb+Pb collisions with the ATLAS detector

Two-particle pseudorapidity correlations are measured in √s NN = 2.76 TeV Pb+Pb, √s NN = 5.02 TeV p +Pb and √s = 13 TeV pp collisions [ATLAS Collaboration, ATLAS-CONF-2015-051; ATLAS-CONF-2015-020]. Correlation function is measured using charged particles in the pseudorapidity range |η|<2.4 with transverse momentum p T >0.2 GeV, and it is measured as a function of event multiplicity, defined by number of charged particles with |η|<2.5 and p T >0.4 GeV. The correlation function is decomposed into a short-range component (SRC) and a long-range component (LRC). The SRC differs significantly between the opposite-charge pairs and same-charge pairs, and between the three collision systems at similar multiplicity. The LRC is described approximately by 1 + n1n2 in all collision systems over the full multiplicity range. The values of are consistent between the opposite-charge and same-charge pairs, and are similar for the three collision systems at similar multiplicity. The values of and the magnitude of the SRC both follow a power-law dependence on the event multiplicity.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

DOE OSTI2021

Multiplicity scaling of light nuclei production in relativistic heavy-ion collisions

Using the nucleon coalescence model based on kinetic freeze-out nucleons from the 3D MUSIC+UrQMD and the 2D VISHNU hybrid model with a crossover equation of state, we study the multiplicity dependence of deuteron ( d ) and triton ( t ) production from central to peripheral Au+Au collisions at s NN = 7.7, 14.5, 19.6, 27, 39, 62.4 and 200 GeV and Pb+Pb at s NN = 2.76 TeV, respectively. It is found that the ratio N t N p / N d 2 of the proton yield N p , deuteron yield N d and triton yield N t exhibits a scaling behavior in its multiplicity dependence, i.e., decreasing monotonically with increasing charged-particle multiplicity. A similar multiplicity scaling of this ratio is also found in the nucleon coalescence calculation based on kinetic freeze-out nucleons from a multiphase transport (AMPT) model. The scaling behavior of N t N p / N d 2 can be naturally explained by the interplay between the sizes of light nuclei and the nucleon emission source. We further argue that the multiplicity scaling of N t N p / N d 2 can be used to validate the production mechanism of light nuclei, and the collision energy dependence of this yield ratio can further serve as a baseline in the search for the QCD critical point in relativistic heavy-ion collisions.

79 ASTRONOMY AND ASTROPHYSICS↗

DOE OSTI2013

Multiple proviral integration events after virological synapse-mediated HIV-1 spread

HIV-1 can move directly between T cells via virological synapses (VS). Although aspects of the molecular and cellular mechanisms underlying this mode of spread have been elucidated, the outcomes for infection of the target cell remain incompletely understood. We set out to determine whether HIV-1 transfer via VS results in productive, high-multiplicity HIV-1 infection. We found that HIV-1 cell-to-cell spread resulted in nuclear import of multiple proviruses into target cells as seen by fluorescence in-situ hybridization. Proviral integration into the target cell genome was significantly higher than that seen in a cell-free infection system, and consequent de novo viral DNA and RNA production in the target cell detected by quantitative PCR increased over time. Our data show efficient proviral integration across VS, implying the probability of multiple integration events in target cells that drive productive T cell infection. - Highlights: • Cell-to-cell HIV-1 infection delivers multiple vRNA copies to the target cell. • Cell-to-cell infection results in productive infection of the target cell. • Cell-to-cell transmission is more efficient than cell-free HIV-1 infection. • Suggests a mechanism for recombination in cells infected with multiple viral genomes.

60 APPLIED LIFE SCIENCES↗

DOE OSTI2024

Innovative dead-time correction and background subtraction for neutron multiplicity measurements using neural networks

Abstract The number of neutrons emitted from a nuclear reaction plays a crucial role in various fields, including nuclear theory, nuclear nonproliferation, nuclear energy and nuclear criticality safety. Accurate determination of neutron multiplicities requires the application of several corrections, with dead-time correction and background subtraction being particularly significant. These corrections become more challenging for neutron detectors with time-dependent neutron capture. In this work, we perform a comprehensive study of three existing methods used for dead-time correction and background subtraction in neutron detectors with time-dependent neutron capture. The methods were tested for dead-times in the range from 0 to 1 μs using a Monte Carlo model simulating the dead-time and background effects in the standard neutron multiplicity probability distribution of $$^{252}$$ 252 Cf. The previous methods showed larger than desired uncertainty or systematic trade off. Those uncertainties prompted the development of a novel approach using neural networks trained with data from Monte Carlo simulations. The Neural Network method enabled the correction of neutron multiplicity probabilities more accurately than the other methods with fractional errors smaller than 3% for multiplicities around the peak of $$^{252}$$ 252 Cf. A similar approach using neural networks could be applied to problems where the system being studied can be accurately simulated without having an accurate analytical description available. The neural network method presented in this paper can be easily expanded if multiplicities greater than 10 are expected.

73 NUCLEAR PHYSICS AND RADIATION PHYSICS↗