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At least 397 records · Page 22

RapidEELS: machine learning for denoising and classification in rapid acquisition electron energy loss spectroscopy

Recent advances in detectors for imaging and spectroscopy have afforded in situ, rapid acquisition of hyperspectral data. While electron energy loss spectroscopy (EELS) data acquisition speeds with electron counting are regularly reaching 400 frames per second with near-zero read noise, signal to noise ratio (SNR) remains a challenge owing to fundamental counting statistics. In order to advance understanding of transient materials phenomena during rapid acquisition EELS, trustworthy analysis of noisy spectra must be demonstrated. In this study, we applied machine learning techniques to denoise high frame rate spectra, benchmarking with slower frame rate “ground truths”. The results provide a foundation for reliable use of low SNR data acquired in rapid, in-situ spectroscopy experiments. Such a tool-set is a first step toward both automation in microscopy as well as use of these methods to interrogate otherwise poorly understood transformations.

36 MATERIALS SCIENCE↗

High resolution >40 keV x-ray radiography using an edge-on micro-flag backlighter at NIF-ARC

Radiography of low-contrast features in high-density materials evolving on a nanosecond timescale requires a bright photon source in the tens of keV range with high temporal and spatial resolution. One application for sources in this category is the study of dynamic material strength in samples compressed to Mbar pressures at the National Ignition Facility, high-resolution measurements of plastic deformation under conditions relevant to meteor impacts, geophysics, armor development, and inertial confinement fusion. Here, we present radiographic data and the modulation transfer function (MTF) analysis of a multi-component test object probed at ~100 keV effective backlighter energy using a 5 μm-thin dysprosium foil driven by the NIF Advanced Radiographic Capability (ARC) short-pulse laser (~2 kJ, 10 ps). The thin edge of the foil acts as a bright line-projection source of hard x rays, which images the test object at 13.2× magnification into a filtered and shielded image plate detector stack. The system demonstrates a superior contrast of shallow (5 μm amplitude) sinusoidal ripples on gold samples up to 90 μm thick as well as enhanced spatial and temporal resolution using only a small fraction of the laser energy compared to an existing long-pulse-driven backlighter used routinely at the NIF for dynamic strength experiments.

47 OTHER INSTRUMENTATION↗

Characterisation of signal-induced noise in Hamamatsu R11265 Multianode Photomultiplier Tubes

Signal-induced noise is observed in Hamamatsu R11265 Multianode Photomultiplier Tubes, manifesting up to several microseconds after the single photoelectron response signal and localised in specific anodes. The mean number of noise pulses varies between devices, and shows significant dependence on the applied high-voltage. The characterisation of this noise and the mitigation strategies to perform optimal single-photon counting at 40 MHz, as required by the LHCb Ring-Imaging Cherenkov detectors, are reported.

47 OTHER INSTRUMENTATION↗

VitroJet: new features and case studies

Single-particle cryo-electron microscopy has become a widely adopted method in structural biology due to many recent technological advances in microscopes, detectors and image processing. Before being able to inspect a biological sample in an electron microscope, it needs to be deposited in a thin layer on a grid and rapidly frozen. The VitroJet was designed with this aim, as well as avoiding the delicate manual handling and transfer steps that occur during the conventional grid-preparation process. Since its creation, numerous technical developments have resulted in a device that is now widely utilized in multiple laboratories worldwide. It features plasma treatment, low-volume sample deposition through pin printing, optical ice-thickness measurement and cryofixation of pre-clipped Autogrids through jet vitrification. This paper presents recent technical improvements to the VitroJet and the benefits that it brings to the cryo-EM workflow. A wide variety of applications are shown: membrane proteins, nucleosomes, fatty-acid synthase, Tobacco mosaic virus, lipid nanoparticles, tick-borne encephalitis viruses and bacteriophages. These case studies illustrate the advancement of the VitroJet into an instrument that enables accurate control and reproducibility, demonstrating its suitability for time-efficient cryo-EM structure determination.

59 BASIC BIOLOGICAL SCIENCES↗

HSolo v.1.0

SAND2021-11023 O HSolo is a library for estimating similarity, affine, projective homographies from matches produced by image feature detectors such as SURF and SIFT. Sandia National Laboratories is a multimission laboratory managed and operated by National Technology & Engineering Solutions of Sandia, LLC, a wholly owned subsidiary of Honeywell International Inc., for the U.S. Department of Energy’s National Nuclear Security Administration under contract DE-NA0003525.

Gonzales, Antonio↗

Even Higher-Level Synthesis: An Exploration of AI Hardware Accelerators using HLS4ML

With the rise of artificial intelligence, the popularization of deep learning, and a constantly evolving industry, the demand for flexible and efficient tools has never been greater. As algorithms grow more complex, their runtime and energy consumption increase exponentially. Customized hardware accelerators, long used for specific mathematical operations, remain essential for managing modern applications' computational and power demands. Hardware accelerators can speed up complex computations by orders of magnitude, but their manual design and verification processes are often challenging and time-consuming. High-Level Synthesis (HLS) provides a solution by transforming high-level algorithm descriptions, typically written in C++ or SystemC, into synthesizable RTL suitable for hardware implementation. This approach reduces development time for RTL engineers while offering flexibility beyond what traditional handwritten RTL can provide. We extended this capability to the machine-learning domain with the open-source framework hls4ml, which allows neural networks trained in Python frameworks like Tensorflow or PyTorch to be synthesized into efficient hardware representations for the traditional FPGA and ASIC flows. This breakthrough addresses the growing need for reduced design turnaround and easy verification of ML hardware accelerators with low latency and power efficiency constraints. During this tutorial, we will demonstrate how Python complements HLS by simplifying the ML design process, bridging the gap between software and hardware development. Attendees will explore how we translate neural networks modeled in Python into fixed-point C++ models suitable for HLS workflows. We will dive into strategies like Value-Range Analysis and Quantization-Aware Training, which optimize these designs for deployment and evaluate their accuracy, power consumption, and energy efficiency. To exemplify these concepts, experts from Fermilab will share their experiences applying this technology to high-energy physics experiments, where real-time, low-latency processing is critical. Over the years, Fermilab engineers have demonstrated how deep neural networks, optimized for hardware using hls4ml, can meet the stringent requirements of trigger systems at the CERN Large Hadron Collider. These systems rely on rapid decision-making to process immense data volumes while retaining only the most relevant events for further analysis. The application of hls4ml has also been extended to innovative technologies like smart pixel arrays. These smart pixels integrate ML inference capabilities directly into sensor devices, enabling localized data processing at the pixel level. This approach drastically reduces the need to transmit raw data to external processing units, significantly decreasing power consumption and latency. By embedding neural networks within the pixel architecture, the smart pixels can identify and prioritize relevant data in real time, providing a highly efficient solution for edge computing in scenarios such as particle detectors and imaging systems. Fermilab's work highlights the potential of hardware-accelerated ML in scenarios where both speed and power efficiency are mission-critical. Through this tutorial, attendees will gain valuable insights into the challenges and solutions of deploying ML in hardware. Understanding how HLS and hls4ml streamline the development of neural network-based hardware accelerators is fundamental for the industry's future. Participants will learn how these technologies are shaping the future of AI and scientific computing.

Di Guglielmo, Giuseppe [Fermilab]↗

Quantum Vision Transformers for Quark–Gluon Classification

We introduce a hybrid quantum-classical vision transformer architecture, notable for its integration of variational quantum circuits within both the attention mechanism and the multi-layer perceptrons. The research addresses the critical challenge of computational efficiency and resource constraints in analyzing data from the upcoming High Luminosity Large Hadron Collider, presenting the architecture as a potential solution. In particular, we evaluate our method by applying the model to multi-detector jet images from CMS Open Data. The goal is to distinguish quark-initiated from gluon-initiated jets. We successfully train the quantum model and evaluate it via numerical simulations. Using this approach, we achieve classification performance almost on par with the one obtained with the completely classical architecture, considering a similar number of parameters.

Comajoan Cara, Marçal (ORCID:0009000126263752)↗

Ultraviolet stellar spectrophotometry from a balloon platform

A 40 centimeter diameter aperture, balloon-borne telescope and ultraviolet spectrometer is described and selected scientific results are briefly reviewed. The general configuration of the 0.4 angstrom resolution instrument is shown and the utilization of servo-controlled secondary mirror, image dissector detector, and special mirror coatings are discussed. An outlook for astronomical research in the mid-ultraviolet from balloon-borne telescopes is presented together with future development plans for JSC's balloon-borne payload.

Kondo, Y.↗

Proposal to National Aeronautics and Space Administration for continuation of a grazing incidence imaging telescope for X-ray astronomy using sounding rockets

The construction of a high resolution imaging telescope experiment payload suitable for launch on an Astrobee F sounding rocket was proposed. Also integration, launch, and subsequent data analysis effort were included. The payload utilizes major component subassemblies from the HEAO-B satellite program which were nonflight development units for that program. These were the X ray mirror and high resolution imager brassboard detector. The properties of the mirror and detector were discussed. The availability of these items for a sounding rocket experiment were explored with the HEAO-B project office.

Murray, B.↗

Infrared astronomy after IRAS

The development of infrared astronomy in the wake of IRAS is discussed. Attention is given to an overview of next generation infrared telescope technology, with emphasis on the Space Infrared Telescope Facility (SIRTF) which has been built to replace IRAS in the 1990s. Among the instruments to be included on SIRTF are: a wide-field high-resolution camera covering the infrared range 3-30 microns with large arrays of detectors; an imaging photometer operating in the range 3-700 microns; and a spectrograph covering the range 2.5-200 microns with resolutions of 2 and 0.1 percent. Observational missions for the SIRTF are proposed in connection with: planetary formation; star formation; cosmic energy sources; active galactic nuclei; and quasars.

Rieke, G. H.↗

Calibration and analysis for a 0.53 micron incoherent Doppler lidar

A ground based, prototype Doppler lidar is being developed to demonstrate the feasibility of an incoherent detection technique to remotely measure winds in the atmosphere. This prototype system consists of a narrow band, single frequency laser transmitter, a high resolution, Fabry-Perot Interferometer utilizing a multichannel image plane detector and a data acquisition system. A description of the prototype Doppler lidar hardware is given in Rosenberg and Sroga, 1985. The calibration and analysis procedures for this system is described. Preliminary results from data obtained with the system pointed vertically is presented.

Sroga, J.↗

Post flight analysis of NASA standard star trackers recovered from the solar maximum mission

The flight hardware returned after the Solar Maximum Mission Repair Mission was analyzed to determine the effects of 4 years in space. The NASA Standard Star Tracker would be a good candidate for such analysis because it is moderately complex and had a very elaborate calibration during the acceptance procedure. However, the recovery process extensively damaged the cathode of the image dissector detector making proper operation of the tracker and a comparison with preflight characteristics impossible. Otherwise, the tracker functioned nominally during testing.

Newman, P.↗

High resolution diffraction imaging of crystals grown in microgravity and closely related terrestrial crystals

Irregularities found in three crystals grown in space, in four crystals grown entirely on the ground were examined and compared. Irregularities were observed in mercuric iodide, lead tin telluride, triglycine sulfate, and gallium arsenide by high resolution synchrotron x radiation diffraction imaging. Radiation detectors made from mercuric iodide crystals grown in microgravity were reported to perform far better than conventional detectors grown from the same material under full gravity. Effort is now underway to reproduce these 'space' crystals, optimize their properties, and extend comparable superiority to other types of materials.

Steiner, B.↗

EXOSS - A hard X-ray and soft gamma-ray astronomy mission

The Energetic X-ray Observatory on Space Station (EXOSS) is a mission concept for high-sensitivity coded-aperture sky surveys and studies of the spectral and temporal behavior of astrophysical sources from approximately 3 keV to 1 MeV. The scientific motivation for the mission and the instrument requirements, including the need for high angular resolution to resolve and identify numerous detectable sources, are summarized. Two baseline telescopes are described: one employing a 1.4-sq-m array of Xe gas imaging proportional counters to cover the 3 to 100 keV range with 1 arcmin resolution; the second using a 2.8-sq-m array of NaI/CsI imaging phoswich detectors to span the 20 keV to MeV range with 12 arcmin resolution.

Cook, W. R.↗

Segmented mirror figure control for a space-based far-IR astronomical telescope

For segmented large mirrors to be used effectively for astronomy they must be actively aligned and controlled to extreme levels of precision. We consider the figure control problem for a spaceborne far-IR telescope, the Precision Segmented Reflector Project Focus Moderate Mission Telescope. We propose a two-stage approach. A figure initialization controller is used to achieve initial phasing and alignment of the telescope using an imaging science detector. A figure maintenance controller keeps the telescope aligned during normal operation using a laser metrology optical truss sensor system. We show that performance of any figure control system is subject to limits on the controllability of the wavefront. Maintenance controllers are additionally limited by considerations of the observability of the wavefront from the maintenance sensors. We show preliminary results for the figure initialization controller. We present a 'Wavefront Compensation' method for figure maintenance control that minimizes wavefront errors due to misalignment errors.

Redding, David↗

Balloon-based interferometric techniques

A balloon-borne triple-etalon Fabry-Perot Interferometer, observing the Doppler shifts of absorption lines caused by molecular oxygen and water vapor in the far red/near infrared spectrum of backscattered sunlight, has been used to evaluate a passive spaceborne remote sensing technique for measuring winds in the troposphere and stratosphere. There have been two successful high altitude balloon flights of the prototype UCL instrument from the National Scientific Balloon Facility at Palestine, TE (May 80, Oct. 83). The results from these flights have demonstrated that an interferometer with adequate resolution, stability and sensitivity can be built. The wind data are of comparable quality to those obtained from operational techniques (balloon and rocket sonde, cloud-top drift analysis, and from the gradient wind analysis of satellite radiance measurements). However, the interferometric data can provide a regular global grid, over a height range from 5 to 50 km in regions of clear air. Between the middle troposphere (5 km) and the upper stratosphere (40 to 50 km), an optimized instrument can make wind measurements over the daylit hemisphere with an accuracy of about 3 to 5 m/sec (2 sigma). It is possible to obtain full height profiles between altitudes of 5 and 50 km, with 4 km height resolution, and a spatial resolution of about 200 km, along the orbit track. Below an altitude of about 10 km, Fraunhofer lines of solar origin are possible targets of the Doppler wind analysis. Above an altitude of 50 km, the weakness of the backscattered solar spectrum (decreasing air density) is coupled with the low absorption crosssection of all atmospheric species in the spectral region up to 800 nm (where imaging photon detectors can be used), causing the along-the-track resolution (or error) to increase beyond values useful for operational purposes. Within the region of optimum performance (5 to 50 km), however, the technique is a valuable potential complement to existing wind measuring systems and can provide a low cost addition to powerful active (LIDAR) wind measuring systems now under development.

Rees, David↗

Development of a 0.5 micrometer incoherent Doppler lidar for space application

This paper describes the current status of a prototype 0.53 micrometer Doppler lidar system under development at RCA. This system consists of a frequency doubled Nd:YAG laser constrained to yield a narrow bandwidth, single frequency pulse, a Fabry-Perot Inteferometer (FPI) using an Image Plane Detector (IPD) to measure the backscatter spectrum for each pulse and a Data Acquisition System (DAS) to sample, store, and analyze the backscattered signal. These individual subsystem components have been assembled and preliminary atmospheric testing has recently begun. Atmospheric backscatter spectra are presented which demonstrate the capabilities of this system to distinguish between return signals from aerosols, molecules, and clouds.

Rosenberg, A.↗

Development and applications of laser-induced incandescence

Several NASA-funded investigations focus on soot processes and radiative influences of soot in diffusion flames given their simplicity, practical significance, and potential for theoretical modeling. Among the physical parameters characterizing soot, soot volume fraction, f(sub v), a function of particle size and number density, is often of chief practical interest in these investigations, as this is the geometrical property that directly impacts radiative characteristics and the temperature field of the flame and is basic to understanding soot growth and oxidation processes. Diffusion flames, however, present a number of challenges to the determination of f(sub v) via traditional extinction measurements. Laser-induced incandescence (LII) possesses several advantages compared to line-of-sight extinction techniques for determination of f(sub v). Since LII is not a line-of-sight technique, similar to fluorescence, it possesses geometric versatility allowing spatially resolved measurements of f(sub v) in real time in nonaxisymmetric systems without using deconvolution techniques. The spatial resolution of LII is determined by the detector and imaging magnification used. Neither absorption by polycyclic aromatic hydrocarbons (PAH's) nor scattering contributes to the signal. Temporal capabilities are limited only by the laser pulse and camera gate duration, with measurements having been demonstrated with 10 ns resolution. Because of these advantages, LII should be applicable to a variety of combustion processes involving both homogeneous and heterogeneous phases. Our work has focussed on characterization of the technique as well as exploration of its capabilities and is briefly described.

Vanderwal, Randy L.↗