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At least 397 records · Page 22

Nanotechnology in agriculture: Opportunities, toxicological implications, and occupational risks

Nanotechnology has the potential to make a beneficial impact on several agricultural, forestry, and environmental challenges, such as urbanization, energy constraints, and sustainable use of resources. However, new environmental and human health hazards may emerge from nano-enhanced applications. This raises concerns for agricultural workers who may become primarily exposed to such xenobiotics during their job tasks. The aim of this review is to discuss promising solutions that nanotechnology may provide in agricultural activities, with a specific focus on critical aspects, challenging issues, and research needs for occupational risk assessment and management in this emerging field. Eco-toxicological aspects were not the focus of the review. Nano-fertilizers, (nano-sized nutrients, nano-coated fertilizers, or engineered metal-oxide or carbon-based nanomaterials per se), and nano-pesticides, (nano-formulations of traditional active ingredients or inorganic nanomaterials), may provide a targeted/controlled release of agrochemicals, aimed to obtain their fullest biological efficacy without over-dosage. Nano-sensors and nano-remediation methods may detect and remove environmental contaminants. However, limited knowledge concerning nanomaterial biosafety, adverse effects, fate, and acquired biological reactivity once dispersed into the environment, requires further scientific efforts to assess possible nano-agricultural risks. In this perspective, toxicological research should be aimed to define nanomaterial hazards and levels of exposure along the life-cycle of nano-enabled products, and to assess those physico-chemical features affecting nanomaterial toxicity, possible interactions with agro-system co-formulants, and stressors. Overall, this review highlights the importance to define adequate risk management strategies for workers, occupational safety practices and policies, as well as to develop a responsible regulatory consensus on nanotechnology in agriculture. - Highlights: • Nanotechnology can help precision farming and sustainable agriculture development. • Nano-innovations for agriculture may impact human and environmental health. • Workers exposed to nanomaterials may face emerging occupational risks. • Toxicology should assess the nanomaterial impact on agrosystems and human beings. • Toxicological research may guide effective risk assessment and management processes.

54 ENVIRONMENTAL SCIENCES↗

Design and Flight Testing of an Inflatable Sunshield for the NGST

The Next Generation Space Telescope (NGST) mission is scheduled to launch in 2007 and be stationed at L2 for a mission life of ten years. The large aperture mirror and optical detectors aboard NGST require shielding from the constant solar energy seen at this orbit. The government reference NGST design, called the Yardstick, baselined a sunshield using an inflation deployment system. During the formulation phase, NGST is spending approximately 25% of the overall budget to foster the development of new technology. The goal is to develop and demonstrate enabling or enhancing technology and provide innovative solutions for the design of the NGST observatory. Inflatable technology falls in the category of enhancing technology due to its advantages in weight, stowed volume and cost. The Inflatable Sunshield in Space (ISIS) flight experiment will provide a realistic space flight demonstration of an inflatable sunshield. The supporting technology development program will provide an information base for the design, manufacture, assembly and testing of large thin membranes and inflatable structural elements for space structures. The ISIS experiment will demonstrate the feasibility of using inflatable technology to passively cool optical systems for NGST and provide correlation between analytical predictions and on orbit results. The experiment will be performed on a Hitchhiker/Space Shuttle mission in late 2001. The ISIS mission is an effort to address several major technical challenges of the NGST inflatable sunshield, namely controlled inflation deployment, plenarity and separation of large stretched membranes, space rigidization of inflatable booms, and dynamic modeling and simulation. This paper will describe the design of the flight experiment and the testing to be performed on-orbit.

Adams, Michael L.↗

Vibration transmission through rolling element bearings. III - Geared rotor system studies

The bearing matrix formulations proposed by Lim and Singh (1990) are extended to analyze the overall dynamics of a geared rotor system which includes a spur gear pair, shafts, rolling-element bearings, a motor, a load, a casing, and flexible or rigid mounts. For this purpose, discrete vibration models are developed and used to predict vibration transmission through the bearings and to investigate the effects of the bearing, casing, and mount dynamics on the dynamic characteristics of the internal rotating system. Analytical predictions show that the theory is capable of predicting the bearing and mount moment transmissibilities in addition to the force transmissibilities. The predicted flexural vibrations of the casing plate are in good agreement with measurements conducted on an experimental set-up that consisted of a high-precision beam and pinion, and four identical rolling element bearings contained in a flexible casing mounted rigidly on a massive foundation.

Lim, T. C.↗

Geometry Optimization of Cable-Based Actuation for Small-Scale Model Testing of a Floating Marine Turbine: Preprint

This research aims to apply combined wave and tidal current loads to a small-scale floating marine current turbine in a wave tank, where an actuation system applies hydrodynamic and mooring forces on the hardware based on results from a simulation. We use a real-time hybrid test setup with physical wave forcing from the wave tank and simulated current and mooring forces implemented through a tensioned cable array. For this paper, we developed an optimization algorithm that adjusts the hardware geometry of the cable array to achieve more efficient tension allocation across the cables for the loads that need to be actuated. By adjusting the points where the cables are attached to the floating platform and the angles between the platform and the winches, an optimal cable geometry can be found to minimize tension variations in the lines, maintain the desired pretension, and prevent excessive tensions. We present the optimization problem formulation, the actuation system evaluation approach, and optimization results that show effective cable actuation setups that are being considered for implementation in the wave tank tests.

cable-based actuation↗

Numerical methods and hypoexponential approximations for gamma distributed delay differential equations

Abstract Gamma distributed delay differential equations (DDEs) arise naturally in many modelling applications. However, appropriate numerical methods for generic gamma distributed DDEs have not previously been implemented. Modellers have therefore resorted to approximating the gamma distribution with an Erlang distribution and using the linear chain technique to derive an equivalent system of ordinary differential equations (ODEs). In this work, we address the lack of appropriate numerical tools for gamma distributed DDEs in two ways. First, we develop a functional continuous Runge–Kutta (FCRK) method to numerically integrate the gamma distributed DDE without resorting to Erlang approximation. We prove the fourth-order convergence of the FCRK method and perform numerical tests to demonstrate the accuracy of the new numerical method. Nevertheless, FCRK methods for infinite delay DDEs are not widely available in existing scientific software packages. As an alternative approach to solving gamma distributed DDEs, we also derive a hypoexponential approximation of the gamma distributed DDE. This hypoexponential approach is a more accurate approximation of the true gamma distributed DDE than the common Erlang approximation but, like the Erlang approximation, can be formulated as a system of ODEs and solved numerically using standard ODE software. Using our FCRK method to provide reference solutions, we show that the common Erlang approximation may produce solutions that are qualitatively different from the underlying gamma distributed DDE. However, the proposed hypoexponential approximations do not have this limitation. Finally, we apply our hypoexponential approximations to perform statistical inference on synthetic epidemiological data to illustrate the utility of the hypoexponential approximation.

97 MATHEMATICS AND COMPUTING↗

System simulation on advanced earth-orbital satellite systems

A system simulation capability for advanced earth-orbital satellite systems (AEUSS) is presented. It is based on analytical assessment capabilities formulated for generic satellite systems in earth-orbital missions. The resulting AEOSS is a custom tailored software coded within the framework of the Macintosh version of the Acius relational database program, 4th Dimension. It projects the required power, weight, and cost for a satellite system. These key elements are computed on the component and subsystem levels, and then the system level. Selected performance analyses for essential components and subsystems are included.

Lee, Hwa-Ping↗

GN and C Design Overview and Flight Test Results from NASA's Max Launch Abort System (MLAS)

The National Aeronautics and Space Administration (NASA) Engineering and Safety Center (NESC) designed, developed and flew the alternative Max Launch Abort System (MLAS) as risk mitigation for the baseline Orion spacecraft launch abort system (LAS) already in development. The NESC was tasked with both formulating a conceptual objective system (OS) design of this alternative MLAS as well as demonstrating this concept with a simulated pad abort flight test. The goal was to obtain sufficient flight test data to assess performance, validate models/tools, and to reduce the design and development risks for a MLAS OS. Less than 2 years after Project start the MLAS simulated pad abort flight test was successfully conducted from Wallops Island on July 8, 2009. The entire flight test duration was 88 seconds during which time multiple staging events were performed and nine separate critically timed parachute deployments occurred as scheduled. Overall, the as-flown flight performance was as predicted prior to launch. This paper provides an overview of the guidance navigation and control (GN&C) technical approaches employed on this rapid prototyping activity. This paper describes the methodology used to design the MLAS flight test vehicle (FTV). Lessons that were learned during this rapid prototyping project are also summarized.

Dennehy, Cornelius J.↗

Robust operative diagnosis as problem solving in a hypothesis space

This paper describes an approach that formulates diagnosis of physical systems in operation as problem solving in a hypothesis space. Such a formulation increases robustness by: (1) incremental hypotheses construction via dynamic inputs, (2) reasoning at a higher level of abstraction to construct hypotheses, and (3) partitioning the space by grouping fault hypotheses according to the type of physical system representation and problem solving techniques used in their construction. It was implemented for a turbofan engine and hydraulic subsystem. Evaluation of the implementation on eight actual aircraft accident cases involving engine faults provided very promising results.

Abbott, Kathy H.↗

Pharmaceutical Product Development: Intranasal Scopolamine (INSCOP) Metered Dose Spray

Motion sickness (MS) has been a problem associated with space flight, the modern military and commercial air and water transportation for many years. Clinical studies have shown that scopolamine is the most effective medication for the prevention of motion sickness (Dornhoffer et al, 2004); however, the two most common methods of administration (transdermal and oral) have performance limitations that compromise its utility. Intranasal administration offers a noninvasive treatment modality, and has been shown to counter many of the problems associated with oral and transdermal administration. With the elimination of the first pass effect by the liver, intranasal delivery achieves higher and more reliable bioavailability than an equivalent oral dose. This allows for the potential of enhanced efficacy at a reduced dose, thus minimizing the occurrence of untoward side effects. An Intranasal scopolamine (INSCOP) gel formulation was prepared and tested in four ground-based clinical trials under an active Investigational New Drug (IND) application with the Food and Drug Administration (FDA). Although there were early indicators that the intranasal gel formulation was effective, there were aspects of formulation viscosity and the delivery system that were less desirable. The INSCOP gel formulation has since been reformulated into an aqueous spray dosage form packaged in a precise, metered dose delivery system; thereby enhancing dose uniformity, increased user satisfaction and palatability, and a potentially more rapid onset of action. Recent reports of new therapeutic indications for scopolamine has prompted a wide spread interest in new scopolamine dosage forms. The novel dosage form and delivery system of INSCOP spray shows promise as an effective treatment for motion sickness targeted at the armed forces, spaceflight, and commercial sea, air, and space travel markets, as well as prospective psychotherapy for mental and emotional disorders.

Putcha, Lakshmi↗

Community-Based Transactive Coordination Mechanism for Enabling Grid Edge Systems

The changing landscape of the electricity industry, characterized by a surge in distributed energy resources (DERs) and proactive customers, necessitates practical solutions for coordinated operations especially at the distribution-level. This paper introduces a community-based transactive coordination mechanism designed to incentivize customers for providing localized and system-level services reflected through real-time prices. The work presents a bidding approach for communities with DERs, such as solar photovoltaic (PV) and battery energy storage systems (BESS), to formulate their price-responsiveness for retail energy coordination, emphasizing a community-centric model. By sending bidding curves to a third-party, the mechanism enables customers with DER assets to actively participate in localized coordination with the load serving entity (LSE), thereby supplementing each other’s and even the utilities needs through a shared energy economy. The proposed transactive mechanism is implemented leveraging a co-simulation framework that integrates a distribution grid simulator and Python-based agents for performance evaluation. Collaboration with a local utility to access real distribution feeder models and consumption profiles yields simulation results demonstrating the potential to reduce costs by 12\% for communities with DERs like PV and BESS.

Community-based coordination, grid-edge systems, R↗

A data-driven framework for error estimation and mesh-model optimization in system-level thermal-hydraulic simulation

We report over the past decades, several computer codes have been developed for simulation and analysis of thermal-hydraulics and system response in nuclear reactors under operating, abnormal transient, and accident conditions. However, simulation errors and uncertainties still inevitably exist even while these codes have been extensively assessed and used. In this work, a data-driven framework (Optimal Mesh/Model Information System, OMIS) is formulated and demonstrated to estimate simulation error and suggest optimal selection of computational mesh size (i.e., nodalization) and constitutive correlations (e.g., wall functions and turbulence models) for low-fidelity, coarse-mesh thermal-hydraulic simulation, in order to achieve accuracy comparable to that of high-fidelity simulation. Using results from high-fidelity simulations and experimental data with many fast-running low-fidelity simulations, an error database is built and used to train a machine learning model that can determine the relationship between local simulation error and local physical features. This machine learning model is then used to generate insight and help correct low-fidelity simulations for similar physical conditions. The OMIS framework is designed as a modularized six-step procedure and accomplished with state-of-the-art methods and algorithms. A mixed-convection case study was performed to illustrate the entire framework.

22 GENERAL STUDIES OF NUCLEAR REACTORS↗

Identification of linear systems by an asymptotically stable observer

A formulation is presented for the identification of a linear multivariable system from single or multiple sets of input-output data. The system input-output relationship is expressed in terms of an observer, which is made asymptotically stable by an embedded eigenvalue assignment procedure. The prescribed eigenvalues for the observer may be real, complex, mixed real and complex, or zero. In this formulation, the Markov parameters of the observer are identified from input-output data. The Markov parameters of the actual system are then recovered from those of the observer and used to obtain a state space model of the system by standard realization techniques. The basic mathematical formulation is derived, and extensive numerical examples using simulated noise-free data are presented to illustrate the proposed method.

Phan, Minh Q.↗

User's guide of TOUGH2-EGS-MP: A Massively Parallel Simulator with Coupled Geomechanics for Fluid and Heat Flow in Enhanced Geothermal Systems VERSION 1.0

TOUGH2-EGS-MP is a parallel numerical simulation program coupling geomechanics with fluid and heat flow in fractured and porous media, and is applicable for simulation of enhanced geothermal systems (EGS). TOUGH2-EGS-MP is based on the TOUGH2-MP code, the massively parallel version of TOUGH2. In TOUGH2-EGS-MP, the fully-coupled flow-geomechanics model is developed from linear elastic theory for thermo-poro-elastic systems and is formulated in terms of mean normal stress as well as pore pressure and temperature. Reservoir rock properties such as porosity and permeability depend on rock deformation, and the relationships between these two, obtained from poro-elasticity theories and empirical correlations, are incorporated into the simulation. This report provides the user with detailed information on the TOUGH2-EGS-MP mathematical model and instructions for using it for Thermal-Hydrological-Mechanical (THM) simulations. The mathematical model includes the fluid and heat flow equations, geomechanical equation, and discretization of those equations. In addition, the parallel aspects of the code, such as domain partitioning and communication between processors, are also included. Although TOUGH2-EGS-MP has the capability for simulating fluid and heat flows coupled with geomechanical effects, it is up to the user to select the specific coupling process, such as THM or only TH, in a simulation. There are several example problems illustrating applications of this program. These example problems are described in detail and their input data are presented. Their results demonstrate that this program can be used for field-scale geothermal reservoir simulation in porous and fractured media with fluid and heat flow coupled with geomechanical effects.

15 GEOTHERMAL ENERGY↗

User's Guide of TOUGH2-EGS. A Coupled Geomechanical and Reactive Geochemical Simulator for Fluid and Heat Flow in Enhanced Geothermal Systems Version 1.0

TOUGH2-EGS is a numerical simulation program coupling geomechanics and chemical reactions for fluid and heat flows in porous media and fractured reservoirs of enhanced geothermal systems. The simulator includes the fully-coupled geomechanical (THM) module, the fully-coupled geochemical (THC) module, and the sequentially coupled reactive geochemistry (THMC) module. The fully-coupled flow-geomechanics model is developed from the linear elastic theory for the thermo-poro-elastic system and is formulated with the mean normal stress as well as pore pressure and temperature. The chemical reaction is sequentially coupled after solution of flow equations, which provides the flow velocity and phase saturation for the solute transport calculation at each time step. In addition, reservoir rock properties, such as porosity and permeability, are subjected to change due to rock deformation and chemical reactions. The relationships between rock properties and geomechanical and chemical effects from poro-elasticity theories and empirical correlations are incorporated into the simulator. This report provides the user with detailed information on both mathematical models and instructions for using TOUGH2-EGS for THM, THC or THMC simulations. The mathematical models include the fluid and heat flow equations, geomechanical equation, reactive geochemistry equations, and discretization methods. Although TOUGH2-EGS has the capability for simulating fluid and heat flows coupled with both geomechanical and chemical effects, it is up to the users to select the specific coupling process, such as THM, THC, or THMC in a simulation. There are several example problems illustrating the applications of this program. These example problems are described in details and their input data are presented. The results demonstrate that this program can be used for field-scale geothermal reservoir simulation with fluid and heat flow, geomechanical effect, and chemical reaction in porous and fractured media.

15 GEOTHERMAL ENERGY↗

The Method of Finite Averages

The Method of Finite Averages (MoFA) is a rigorous multiscale modeling methodology for efficiently modeling multi-physical phenomena in heterogeneous porous media. The code developed in this project aims to perform the numerical calculations required to formulate, implement, and verify MoFA models for Earth and Energy systems (i.e., model verification refers to performing fully-resolved simulations of the systems and comparing their results to those of the models). In general, MoFA transforms partial differential equations (PDEs) describing the fine-scale physics of a system into coupled ordinary differential equations (ODEs)---in time---that describe the coarse-scale---or "average"---physical behaviors of the system. This transformation significantly expedites system simulation, as the coarse-scale ODEs involve vastly fewer degrees of freedom than the fine-scale PDEs. The code developed under this project will allow users to 1.) generate system geometries and numerical meshes, 2.) solve the PDE and ODE systems required for MoFA model formulation and implementation, 3.) solve the PDE systems required to obtain fully-resolved simulation results for model verification, and 4.) compare and plot results (e.g., the model and fully-resolved simulation solutions, the error between the solutions, etc.).

Pietrzyk, KyleM [Lawrence Livermore National Labor↗

On the use of the consistent mass matrix in flexible multibody systems

Two different methods are used in finite element structural analysis to define element mass distribution: consistent and lumped mass approximations. The lumped mass method is currently favored in multibody dynamics software packages because of its computational efficiency. This paper, however, presents a multibody dynamics formulation based on the consistent mass approach which should prove to be as computationally efficient as the lumped mass approach. It is shown that when component flexibility is modelled using modal coordinates, the equations of motion, as formulated by these two methods, are very similar in appearance, thereby facilitating their comparison. It is also shown, through simulation of a simple multibody system, that a system formulated with the lumped mass approximation will often require more finite elements and smaller integration step sizes than the corresponding consistent mass system.

Anthony, Tobin C.↗

Generalized Continuum Phenomenological Model of Viscous Fluid: Analysis of Local Mass Displacements

The concept of local mass displacements (as a measure of nonlocality of the state of a physically small element of a body) is used to formulate a complete system of relations of the gradient-type mathematical model of viscous compressible fluid. In this model, the relationship between the thermomechanical processes and the process of local mass displacements, its irreversibility, and the inertia properties are taken into account. It is shown that, in the stationary approximation, the obtained system of relations enables us to justify the appearance of wedging pressure in thin interlayers of fluid.

42 ENGINEERING↗

Equations of the Local Gradient Electromagnetothermomechanics of Polarizable Nonferromagnetic Bodies with Regard for Electric Quadrupole Moments

We formulate a complete system of relations of the local gradient electromagnetothermomechanics of electrically conductive nonferromagnetic polarizable solid media. The nonlocal character of the constitutive relations of the proposed mathematical model is explained by the presence of electric quadrupole moments in the polarization current. As a result of taking into account these moments, the space of parameters of the thermodynamic state of the body is expanded by including a pair of additional conjugate parameters, namely, the quadrupole moment and the gradient of the vector of electric-field intensity. It is shown that the developed model takes into account the electromechanical interaction for materials with high level of symmetry (isotropic materials) and describes the flexoelectric and thermopolarization effects. We also present the key system of equations for a physically and geometrically linear medium.

97 MATHEMATICS AND COMPUTING↗