Configuration of the Xilinx Zynq-7000 All Programmable SoC Memory Resources for Loosely-Coupled Lockstep Applications.
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Described herein are various technologies pertaining to confirming an integrity of a FPGA. A verifier circuit is placed into an FPGA bitstream to enable external verification of the FPGA configuration in real time without requiring readout of the FPGA configuration itself. Number generators are utilized to generate a key which is shared between the FPGA and an external verification component (VC). The key is utilized to configure an initial state of sequence registers respectively located on both the FPGA and the VC. When the FPGA is operating with an approved configuration, output from the sequence registers at the FPGA and the VC are the same.
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Described herein is a method for identifying synthetic inducible promoters that have specified induction and/or repression for DNA binding proteins such as an allosteric transcription factor and an inducer molecule. The method includes an in vitro selection from an unselected polynucleotide library comprising a plurality of random degeneracies, and an in vivo selection to produce an induced promoter library. Produced is an induction table, which allows the selection of a promoter with specific induction and/or repression properties. Also included are biosensors containing the synthetic inducible promoters.
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Provided are implantable, injectable and/or surface mounted biomedical devices and related methods for interfacing with a target tissue. The devices have a substrate, one or more microfluidic channels embedded in or supported by the substrate and a fluid actuator in operational communication with one or more reservoirs and responsive to a wireless control signal. The components of the device are specially configured and packaged to be ultra-thin and mechanically compliant. In some embodiments, the devices are self-powered and fully implantable. The devices can be shaped to provide injection in a minimally invasive manner, thereby avoiding unnecessary tissue damage and providing a platform for long-term implantation for interfacing with biological tissue.
A pseudo-random sequence generator for use within a universal lidar system and its corresponding method of operation. The pseudo-random sequence generator uses synchronized shift registers that are in series Binary adders are provided. The signal output of each of the shift registers is tapped and directed to the binary adders. High-speed switches are provided between the shift registers and the binary adders. The switches are programmed to connect only two of the shift registers to the binary adders for each of the pseudo-random patterns being generated. The binary adders generate an output signal that is received by the first shift register. The signal propagates through all the shift registers to the last shift register. The last shift register outputs a pseudo-random sequence.
The United Kingdom Government remains committed to the policy of geological disposal. All major nuclear nations are actively pursuing geological disposal. It is internationally recognised that geological disposal represents the safest and most sustainable option as the end point of the management of high level waste and spent fuel considered as waste. Other countries that have also decided on a policy of geological disposal include Canada, Finland, France, Switzerland, Sweden and the United States of America. The United Kingdom Government continues to favour an approach to siting a Geological Disposal Facility that is based on the willingness of local communities to participate in the siting process. Construction and operation of a Geological Disposal Facility will be a multi-billion pound project that will provide skilled employment for hundreds of people over many decades. It will contribute greatly to the local economy and wider socio-economic framework. There are also likely to be spin-off industry benefits, infrastructure investments, benefits to local education or academic resources, and positive impacts on local service industries that support the facility and its workforce. It is also likely to involve major investments in local transport facilities and other infrastructure, which would remain after the facility had been closed. The United Kingdom Government published a renewed process for siting a Geological Disposal Facility in 2014 - the Implementing Geological Disposal White Paper. This paper discusses the status of activities in the 2014 White Paper that have been accomplished or are underway through to 2016. (authors)
This paper analyses some challenges of environmental rehabilitation (ER) projects in developing countries that the authors have encountered over the past two decades in many parts of the world, discusses the reasons and proposes ways to mitigate them. In the life cycle of an ER project, some stages that are particularly decisive for the lasting rehabilitation success are considered here: (1) site characterisation/baseline studies, (2) justification and development of remediation objectives, site end states and a remediation strategy, and (3) the after-care phase. This paper argues that the time available in many ER projects in developing countries using international funding is very often insufficient, and discusses the reasons for some of the most important bottlenecks: (1) time realistically required to produce thorough baseline data and obtain historic site information that are indispensable to develop a robust remediation design, (2) lack of an adequate legal and regulatory framework, overlapping and/or conflicting provisions of national standards and discrepancies with international best practice, (3) unmanaged stakeholder expectations regarding the actual health and environmental risks, justification and prioritisation of remedial actions, and the achievable remediation end state. Insufficient resources for after-care, monitoring and, if required, corrective action is another major issue that, in the experience of the authors, jeopardises the sustainability of remediation success. Consequently by applying the lessons learnt from previous ER projects in developing (and developed) countries and taking them on board during the programming phase of new ER projects, international funding agencies could greatly help to avoid these obstacles. (authors)
The Aspo Hard Rock Laboratory (HRL), located in the Simpevarp area in the municipality of Oskarshamn in Sweden, Figure 1, constitutes an important part of the Swedish Nuclear Fuel and Waste Management (SKB) work with design and construction of a deep geological repository for final disposal of spent nuclear fuel. One of the fundamental reasons behind SKB's decision to construct an underground laboratory was to create an opportunity for research, development and demonstration in a realistic and undisturbed rock environment down to repository depth. Most of the research has concerned with processes of importance for the long-term safety of a future final repository and the capability to model the processes taking place at repository depth. Demonstration addresses the performance of the engineered barriers and practical means of constructing a repository and emplacing the canisters containing spent fuel. SKB will in the coming years more focus on using the Aspo HRL for demonstrating technology for and function of important parts of the repository system before constructing and operate the spent nuclear fuel repository in Forsmark. Aspo HRL includes both a research village with office space for 100 persons and different laboratories, e.g. Chemistry and Material Science Laboratory and Bentonite Laboratory, and an underground research laboratory to a depth of 460 m. The Aspo HRL is also open for other organisations to be used for their own projects and experiments not only related to nuclear waste management research. (authors)
The Czech Republic's deep geological repository (DGR) policy sets out a number of important milestones including the selection of candidate sites by 2018 and the selection of a final site by 2025. The final commissioning of the Czech DGR is planned for 2065. In 2010 a screening process was completed employing geological and other criteria that resulted in the identification of 7 potentially suitable sites, all situated in crystalline - granite host rock environments. The next step of the process will result in a reduction both in the number of sites and the surface area of remaining sites based on preliminary safety evaluations and socioeconomic, political and environmental criteria. In order to better understand the behaviour of crystalline host rock environments for DGR safety case purposes, the Radioactive Waste Repository Authority (RAWRA) made decided to enhance the extent of in-situ measurements and research at a depth corresponding to that of the future DGR. In the second half of 2013, RAWRA commenced the construction of the Bukov Underground Research Facility (Bukov URF) in the southern section of the Rozna uranium mine at a depth of 600 m below the earth's surface in a geologically well-mapped area of a Moldanubic crystalline rock formation which is composed principally of migmatised gneisses, migmatites and granulites. The Bukov URF will be, first and foremost, a research facility at which work will be conducted focusing on the taking of geophysical measurements, petrographic, mineralogic, geochemical research and the in-situ determination of the physical - mechanical, geochemical and hydrogeological properties of the host rock massif. The research results will form input data which will be used to both support and improve the safety of the future DGR. (authors)