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At least 379 records · Page 21

Structural basis for botulinum neurotoxin E recognition of synaptic vesicle protein 2

Botulinum neurotoxin E (BoNT/E) is one of the major causes of human botulism and paradoxically also a promising therapeutic agent. Here we determined the co-crystal structures of the receptor-binding domain of BoNT/E (H C E) in complex with its neuronal receptor synaptic vesicle glycoprotein 2A (SV2A) and a nanobody that serves as a ganglioside surrogate. These structures reveal that the protein-protein interactions between H C E and SV2 provide the crucial location and specificity information for H C E to recognize SV2A and SV2B, but not the closely related SV2C. At the same time, H C E exploits a separated sialic acid-binding pocket to mediate recognition of an N-glycan of SV2. Structure-based mutagenesis and functional studies demonstrate that both the protein-protein and protein-glycan associations are essential for SV2A-mediated cell entry of BoNT/E and for its potent neurotoxicity. Our studies establish the structural basis to understand the receptor-specificity of BoNT/E and to engineer BoNT/E variants for new clinical applications.

59 BASIC BIOLOGICAL SCIENCES↗

On the mechanism of soot nucleation. II. E-bridge formation at the PAH bay

A recently proposed mechanism of soot nucleation based upon the formation of a rotationally-activated dimer in the collision of an aromatic molecule and a radical leading to a stable, doubly-bonded E-bridge between them, rooted in the existence of a five-membered ring on the molecule edge, has been further investigated with a focus on the 5-6 E-bridge forming in the reaction of a PAH cyclopenta group with a bay site of another PAH. As a prototype reaction of this kind, we examined the reaction between 4-phenanthrenyl and acenaphthylene and, to project these results to larger aromatic structures, we also explored the size effect of the E-bridge forming reactions by computing the 1-naphthyl + acenaphthylene system and comparing these results with the prior results for pyrenyl + acepyrene. The two systems have been studied through high-level G3(MP2,CC)//B3LYP/6-311G(d,p) ab initio calculations of their potential energy surfaces combined with the RRKM/Master Equation calculations of reaction rate constants. With PAH monomers of similar sizes involved, the formation of E-bridge structures at the bay radical sites appeared to be faster and lead to increased nucleation rates as compared to the zigzag-forming ones. Furthermore, a model combining both the bay and zigzag rotationally-induced formation of E-bridges successfully reaches the level of nucleation fluxes comparable to those of the irreversible pyrene dimerization, thus affirming the rotationally-activated dimerization as a feasible mechanism for soot particle nucleation.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

Anticathode effect on electron kinetics in electron beam generated E × B plasma

Electron beam (e-beam) generated plasmas with applied crossed electric and magnetic (E x B) fields are promising for low damage processing of materials with applications to microelectronics and quantum information systems. In cylindrical e-beam E x B plasmas, radial confinement of electrons and ions is achieved by an axial magnetic field and radial electric field, respectively. To control the axial confinement of electrons, such e-beam generated plasma sources may incorporate a conducting boundary known as an anticathode, which is placed on the axially opposite side of the plasma from the cathode. In this work, it is shown that varying the anticathode voltage bias can control the degree to which the anticathode collects or repels incident electrons, allowing control of warm electron (electron energies in 10–30 eV range) and beam electron population confinement. It is suggested that the effect of the anticathode bias on the formation of these distinct electron populations is also associated with the transition between weak turbulence and strong Langmuir turbulence.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

Empirical evaluation of all unique Cas9 protospacers in E. coli reveal widespread functionality and rules for gRNA design

The Cas9 nuclease has become central to modern methods and technologies in synthetic biology, largely due to the ease with which it can be targeted to specific DNA loci via guide RNAs (gRNAs). Reports vary widely on the actual specificity of this targeting, with some studies observing 60% of gRNAs possessing no activity against the genome, yet an assumption persists within the E. coli community that inactive gRNAs are rare. To resolve these contradictions, we evaluated the activity of 463 000 unique gRNAs in the E. coli K12 MG1655 genome. We show that the overwhelming majority (at least 93%) of unique gRNAs are functional while only 0.3% are nonfunctional. These nonfunctional gRNAs exhibit strong spacer self-interaction, which can either be excluded using a simple design rule or “repaired” during library design. Finally, this work provides the greater microbial synthetic biology community both a set of nearly half a million empirically evaluated E. coli gRNAs as well as a thoroughly evaluated experimental procedure, complete with appropriate controls for Cas9 activity, for conducting Cas9 assays in E. coli specifically and bacteria more generally. Lastly, we have produced a webapp to allow users to easily browse and extract gRNA sequences from the E. coli genome, which can be accessed at https://grna.ornl.gov.

Kammerdiener, Elise K. [Oak Ridge National Laborat↗

Distribution function of nuclei from $\mathcal{e}^±$ scattering in the presence of a strong primordial magnetic field

The amplitude of the primordial magnetic field (PMF) is constrained from observational limits on primordial nuclear abundances. Within this constraint, it is possible that nuclear motion is regulated by Coulomb scattering with electrons and positrons (e ± s), while e ± s are affected by a PMF rather than collisions. For example, at a temperature of 10 9 K, thermal nuclei typically experience ~ 10 21 scatterings per second that are dominated by very small angle scattering leading to minuscule changes in the nuclear kinetic energy of order $\mathcal{O}$(1) eV. In this paper the upper limit on the effects of a possible discretization of the e ± momenta by the PMF on the nuclear momentum distribution is estimated under the extreme assumptions that the momentum of the e ± is relaxed before and after Coulomb scattering to Landau levels, and that during Coulomb scattering the PMF is neglected. This assumption explicitly breaks the time reversal invariance of Coulomb scattering, and the Maxwell-Boltzmann distribution is not a trivial steady state solution of the Boltzmann equation under these assumptions. Here we numerically evaluate the collision terms in the Boltzmann equation, and show that the introduction of a special direction in the e ± distribution by the PMF generates no directional dependence of the collisional destruction term of nuclei. Large anisotropies in the nuclear distribution function are then constrained from big bang nucleosynthesis. Ultimately, we conclude that a PMF does not significantly affect the isotropy or big bang nucleosynthesis.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗

RFA Measurement of E-Cloud Generation Process at Fermilab Main Injector

Fermilab aims to provide greater beam power for the neutrino physics program. As the beam power increases, the unwanted production of secondary electrons in the beam pipe, known as ‘electron cloud’ or ‘E-cloud’ may become disruptive to high intensity operation. Instrumentation has been deployed in the Fermilab Main Injector (MI) to study E-cloud. One of these is a Retard Field Analyzer (RFA) that can be used to directly measure E-cloud generation at the location of the instrument. Studies of the dependence of E-cloud on beam intensity and bunch length have been carried out. The experimental results are compared to POSINST simulations. These simulations are guided by measurements from a Secondary Electron Yield (SEY) test stand installed in the MI to measure the SEY of materials such as the beam pipe stainless steel. The SEY has a strong influence on the E-cloud density. Results of these comprehensive studies comparing the RFA data with realistic MI simulations will be presented.

43 PARTICLE ACCELERATORS↗

Safety Functions and Features, Events and Processes for the E-Area Performance Assessment

The DOE Technical Standard, “Disposal Authorization Statement and Tank Closure Documentation,” (DOE 2017) recommends the use of safety functions and features, events and processes (FEPs) to support development of conceptual models and identification of scenarios to be considered in a performance assessment (PA). The FEP process provides a means to describe how a PA considers and addresses the factors that could influence the performance of key barriers. Understanding the roles of barriers in terms of limiting migration helps to focus on how changes in the system could lead to a situation where those roles cannot be fulfilled and there is the potential for compromised performance. The FEPs screening and review process was used to identify FEPs that are relevant for the EArea Low-Level Waste Facility (LLWF) and specifically those FEPs that could have a detrimental impact on the effectiveness of a given safety function. For this PA, a default list of FEPs developed at the International Atomic Energy Agency (IAEA 2004) and an approach implemented for PAs at the Hanford and Idaho sites (Mehta et al. 2016, DOE-ID 2019) are used to identify processes and events that could influence the effectiveness of a given safety function for the E-Area LLWF (e.g., subsidence can impact the safety function of the cover system and lead to increased infiltration). The Hanford and Idaho PAs represent two of the most recent applications of this approach. The PA evaluates the potential impacts of changes in performance of different features of the system and demonstrates that the safety functions represent multiple and redundant barriers. Barrier analyses, assuming a safety function is not present, also test the robustness of the system in the event of the loss of one or more safety functions. Such evaluations also support a qualitative illustration of the concept of defense in depth. The safety concept for closure of the E-Area LLWF (generically referred to as “E-Area”) encompasses a variety of different features (i.e., administrative controls, natural site features, and engineered barriers) that reduce the potential impacts on human health and the environment from the residual waste that will remain after closure. These features can be represented as a collection of safety functions acting independently and as a system to provide for overall safety. In some applications, there have been attempts to assign numerical expectations to specific safety functions, but that is not the intent in this case. The concept of safety functions is used more qualitatively in two ways for this PA: 1. To illustrate the robustness of the E-Area design, operational practices and closure approach by documenting features that are and are not credited in different modeling cases. 2. To identify the roles of the different features and potential processes and events that could compromise the performance of safety features and need to be considered when developing the modeling approach. This report addresses both safety functions and FEPs for the E-Area PA.

12 MANAGEMENT OF RADIOACTIVE AND NON-RADIOACTIVE W↗

Optimal Transport for e/$\pi^0$ Particle Classification in LArTPC Neutrino Experiments

Separation of electron signals from $\pi^0$ backgrounds is crucial for neutrino oscillation measurements and searches for Beyond Standard Model (BSM) physics in current and future Liquid Argon Time Projection Chamber (LArTPC) experiments. e/$\pi^0$ separation has been a reconstruction challenge since both e and $\pi^0$ present as electromagnetic showers, and often only one out of the two showers produced by $\pi^0$ is reconstructed correctly. This research aims to improve the performance of e/$\pi^0$ separation using optimal transport (OT), by leveraging on the topological differences in the showers produced by the two particles. OT is a method which compares two distributions by finding the most efficient way to transform, or “move” from one to the other. This work uses the MicroBooNE open samples public dataset to test the e/$\pi^0$ separation performance of the method on events which incorporate realistic modeling of LArTPC detector response. Reconstructed 3D energy deposits are projected onto a plane perpendicular to the primary shower, allowing OT to better detect the topological differences between the two types of particles without the need to separately reconstruct all the showers in the events. Different distance metrics for OT are tested and preliminary results on e/$\pi^0$ separation are presented.

43 PARTICLE ACCELERATORS↗

DECOVALEX-2023: Task E Final Report

This is the Task E final report for DECOVALEX-2023. Task E is focused on understanding thermal, two-phase hydrological, and mechanical (TH2M) processes, especially related to predicting brine migration in the excavation damaged zone around a heated excavation in salt. Salt is attractive as a disposal medium for radioactive waste because it is self-healing and is essentially impermeable and essentially non-porous in the far field (away from excavations). Investigation of the short-term (days to years) near-field (centimeters to tens of meters) behavior of salt is important for radioactive waste disposal because this early period strongly controls the amount of brine in a salt repository. Brine leads to corrosion of waste forms and waste packages, and possible dissolution of radionuclides with brine transport being a potential transport vector to the accessible environment. The main test case used in Task E is the ongoing Brine Availability Test in Salt (BATS) heater test located underground at the Waste Isolation Pilot Plant (WIPP) near Carlsbad, New Mexico, USA. The Task was divided into a series of Steps. Step 0 was an introduction to processes in salt, that included matching historical unheated brine inflow data from boreholes at WIPP and matching temperature observations during BATS heater test 1a. Step 1 included validation of models against a thermo-poroelastic analytical solution relevant to heated boreholes in salt, and two-phase flow around an excavation in salt. Step 2 required all the individual components covered in steps 0 and 1 to come together to match observed brine inflow behavior during the BATS 1a heater test. There were a range of approaches from the teams, from mechanistic to prescriptive. Given the uncertainties in the problem, some teams used one- or two-dimensional models of the processes, while other teams included more geometrical complexity in three-dimensional models. The key learning points from Task E have been: • Heat conduction through salt typically requires non-linear thermal conductivity (as a function of temperature), but most models do a good job matching observations, given appropriate adjustments to the applied power and some thermocouple locations. • Thermal pressurization requires coupled thermal-hydrological-mechanical (THM) responses that consider the thermal expansion of the fluid and solid phases. • Initialization of two-phase flow models around a borehole or excavation in salt are more realistically represented as “wetting up”, rather than “drying down” (i.e., the initial state after excavation is mostly dry, rather than mostly wet). • The BATS 1a heater test includes a significant release of brine after the end of heating, which requires a large increase in permeability to recreate. Task E has been a great learning experience for all the teams involved, and feedback from the modeling teams has led to changes in the design of follow-on BATS experiments, which are now ongoing underground at WIPP. There was a balance throughout the task between freedom to model phenomena how each team saw fit, and prescriptiveness in problem design to bring the modeling teams closer together to allow attribution of smaller differences between models to different modeling choices. The modeling approaches seem to go through two phases: an early phase of discovery or testing, and a later phase of refinement and improvement. In future modeling efforts, different field data could be used (e.g., BATS 2) and more time should be included in the processes for teams to make multiple model refinement or even significant changes to their conceptual model or setup, based on lessons learned from the modeling exercise.

12 MANAGEMENT OF RADIOACTIVE AND NON-RADIOACTIVE W↗

Mapping Rare Earths and Toxics in E-Waste via Hyperspectral Imaging and Machine Learning

Electronic waste (e-waste) presents a mounting challenge to environmental sustainability due to its complex composition, which includes high-value rare earth elements, hazardous organic compounds, and non-recyclable plastics. Accurate and scalable material classification is essential for enabling efficient resource recovery and safe recycling practices. This study introduces a confidence-aware classification pipeline that combines mid-infrared hyperspectral imaging (HSI), spectral angle mapping (SAM), and iterative machine learning to perform pixel-level material identification across e-waste devices. A curated spectral library encompassing artificial materials (e.g., plastic iron oxide, galvanized metals), minerals (e.g., allanite, hematite), and organic compounds (e.g., benzanthracene, toluene) was used to generate pseudo-labels, each assigned a confidence score based on SAM-derived spectral similarity. High-confidence samples from seven consumer electronics—digital cameras, keyboards, laptop fans, modems, motherboards, TV remotes, and speakers—were iteratively expanded and classified using models such as Support Vector Machine (SVM), Random Forest, Gradient Boosting Classifier, Partial Least Squares Discriminant Analysis (PLSDA) and Logistic Regression. The best-performing classifiers achieved macro F1 scores approaching 1.0. Results revealed widespread plastic content (dominated by plastic iron oxide), the presence of rare earth-bearing minerals like cerium-containing allanite, and pervasive detection of hazardous organics such as benzanthracene. Principal Component Analysis (PCA) visualizations and confusion matrices confirmed high separability and robust classification performance. This methodology enables precise, non-destructive, and scalable classification of heterogeneous e-waste streams. It supports automated, hazard-aware sorting in recycling workflows, facilitating selective recovery of critical materials and compliance with circular economy goals. The confidence-aware framework provides a foundation for real-time deployment in industrial settings, offering significant implications for smart e-recycling infrastructure and policy-driven material stewardship.

Circular economy↗

Measurements of the temperature and $E$-mode polarization of the cosmic microwave background from the full 500-square-degree SPTpol dataset

Using the full four-year SPTpol 500 deg 2 dataset in both the 95 and 150 GHz frequency bands, we present measurements of the temperature and E-mode polarization of the cosmic microwave background (CMB), as well as the E-mode polarization autopower spectrum (EE) and temperature-E-mode cross-power spectrum (TE) in the angular multipole range 50 < ℓ < 8000. We find the SPTpol dataset to be self-consistent, passing several internal consistency tests based on maps, frequency bands, bandpowers, and cosmological parameters. The full SPTpol dataset is well-fit by the ΛCDM model, for which we find H 0 = 70.48 ± 2.16 km s -1 Mpc -1 and Ω m = 0.271 ± 0.026, when using only the SPTpol data and a Planck-based prior on the optical depth to reionization. The ΛCDM parameter constraints are consistent across the 95 GHz-only, 150 GHz-only, TE-only, and EE-only data splits. Between the ℓ < 1000 and ℓ > 1000 data splits, the ΛCDM parameter constraints are borderline consistent at the ∼2σ level. This consistency improves when including a parameter A L , the degree of lensing of the CMB inferred from the smearing of acoustic peaks. When marginalized over A L , the ΛCDM parameter constraints from SPTpol are consistent with those from Planck. In conclusion, the power spectra presented here are the most sensitive measurements of the lensed CMB damping tail to date for roughly ℓ > 1700 in TE and ℓ > 2000 in EE.

79 ASTRONOMY AND ASTROPHYSICS↗

Search for e → τ charged lepton flavor violation at the EIC with the ECCE detector

The recently approved Electron-Ion Collider (EIC) will provide a unique new opportunity for searches of charged lepton flavor violation (CLFV) and other new physics scenarios. In contrast to the e ↔ μ CLFV transition for which very stringent limits exist, there is still a relatively large discovery space for the e → τ CLFV transition, potentially to be explored by the EIC. Here, with the latest detector design of ECCE (EIC Comprehensive Chromodynamics Experiment) and projected integral luminosity of the EIC, we find the τ-leptons created in the DIS process ep → τX are expected to be identified with high efficiency. A first ECCE simulation study, restricted to the 3-prong τ-decay mode and with limited statistics for the Standard Model backgrounds, estimates that the EIC will be able to improve the current exclusion limit on e → τ CLFV by an order of magnitude. As a result, the very high vertex resolution of the ECCE detector configuration plays a critical role in τ identification.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

Electropolymerized-molecularly imprinted polymers (E-MIPS) as sensing elements for the detection of dengue infection

Here, a straightforward in situ detection method for dengue infection was demonstrated through the molecular imprinting of a dengue nonstructural protein 1 (NS1) epitope into an electropolymerized molecularly imprinted polyterthiophene (E-MIP) film sensor. The key enabling step in the sensor fabrication is based on an epitope imprinting strategy, in which short peptide sequences derived from the original target molecules were employed as the main template for detection and analysis. The formation of the E-MIP sensor films was facilitated using cyclic voltammetry (CV) and monitored in situ by electrochemical quartz crystal microbalance (EC-QCM). Surface properties were analyzed using different techniques including atomic force microscopy (AFM), X-ray photoelectron spectroscopy (XPS), and polarization modulation-infrared reflection-adsorption (PM-IRRAS). The standard calibration curve (R = 0.9830) was generated for the detection of the epitope, Ac-VHTWTEQYKFQ-NH 2 , with a linear range of 0.2 to 30 μg/mL and detection limit of 0.073 μg/mL. A separate calibration curve (R = 0.9786) was obtained using spiked buffered solutions of dengue NS1 protein, which resulted in a linear range of 0.2 to 10 μg/mL and a detection limit of 0.056 μg/mL. The fabricated E-MIP sensor exhibited long-term stability, high sensitivity, and good selectivity towards the targeted molecules. These results indicated that the formation of the exact and stable cavity imprints in terms of size, shape, and functionalities was successful. In our future work, we aim to use our E-MIP sensors for NS1 detection in real-life samples such as serum and blood.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

Response of thermal and fast-ion transport to beam ion population, rotation and T e / T i in the DIII-D steady state hybrid scenario

The thermal and fast-ion transport properties of DIII-D steady-state hybrid discharges with normalized beta β N ≳ 3 are studied at low injected torque and an increased electron to ion temperature ratio T e / T i . Linear stability analysis performed with the TGLF turbulent code indicates that a high-k mode is usually dominant at smaller radii, whereas a low-k mode is usually dominant at larger radii in these plasmas. A reduction in the net injected torque from 8.6 to 4.3 N-m leads to reduced E × B shear and hence, an enhanced turbulence that was observed on the Doppler backscattering diagnostic and was also computed with TGLF. As T e / T i in the core was increased from 0.57 to 0.66 by adding electron cyclotron current drive (ECCD) to these plasmas, higher levels of transport are observed with increased high-k modes indicated by TGLF. The fast-ion transport level varied over an order of magnitude in these discharges depending on whether Alfvén eigenmodes, fishbones, or no instabilities were observed. Hybrid plasmas with fishbones have decreased fast-ion transport, compared to plasmas with Alfvén eigenmodes, since they are resonant with a smaller portion of phase space and their resonance is farther from the wall. This reduction in fast-ion transport with ECCD mitigates the increase in turbulent transport, resulting in higher performance than expected during strong electron heating. Similarly, the lowest fast-ion transport was observed in the low torque plasma, which also led to better than expected performance at this torque value. Finally, the thermal and fast-ion transport changes observed as the torque/rotation and T e / T i are varied indicate possible methods for transferring this scenario to a reactor.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

First evidence of dominant influence of E × B drifts on plasma cooling in an advanced slot divertor for tokamak power exhaust

Addressing power exhaust in tokamaks is presently recognized as one of the major remaining open issues for the development of fusion reactors. At the forefront of this endeavor is the effort to develop an advanced divertor by maximizing dissipation of plasma power and momentum inside the divertor. Here, we demonstrate, for the first time, that the electromagnetic (E × B) drifts exert a key influence on plasma and gas dynamics in a new advanced slot divertor in the DIII-D tokamak, named the small angle slot (SAS). SAS leverages the effect of drifts to achieve a highly dissipative divertor with electron temperature T e ≲ 10 eV over a wide range of plasma densities, for ion B × ∇B away from the divertor, as used for advanced tokamak operation on DIII-D. Modeling with the SOLPS-ITER code shows that for this drift direction, the E × B flow carries particles toward the outer common flux region (CFR) via the private flux region (PFR), reinforcing neutral recycling and enhancing divertor dissipation. In contrast, for the opposite field direction, the E × B flow carries particles away from the outer CFR into the PFR, offsetting the anticipated SAS geometric effects. Furthermore, this finding is an important step in the understanding of the behavior of advanced divertors for achieving a power exhaust solution for fusion reactors.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

E × B flow driven electron temperature bifurcation in a closed slot divertor with ion B × ∇ B away from the X-point in the DIII-D tokamak

An electron temperature bifurcation is observed in the small angle slot divertor, which has been developed to enhance neutral cooling across the divertor target by coupling a closed slot structure with appropriate target shaping. Experiments in the DIII-D tokamak and associated SOLPS-ITER modeling with full drifts find a strong interplay between drifts and divertor geometry on divertor dissipation. The coupling of divertor geometry and drift flows can strongly affect the path towards divertor detachment onset as the plasma density is raised. With the strike point on the inner slanted surface and ion B × ∇B away from the magnetic X-point, bifurcative transitions were observed with sharp decrease of T e towards detachment onset both experimentally and computationally. This differs from the situation for the open divertor where the T e cliff was only observed for ion B × ∇B towards the X-point. SOLPS-ITER modeling with full drifts demonstrates that the magnitude of the E × B drift flow is comparable with the main plasma flow. The reversal of both the poloidal and radial E × B flows near the strike point leads to rapid density accumulation right near the separatrix, which results in bifurcative step transition of divertor conditions with cold plasma across the entire divertor target plate. Furthermore, these results indicate that the interplay between geometry and drifts should be fully taken into account in future fusion reactor divertor designs.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

Measurement of the $\textit{B}(\textit{E}2 ↑)$ strengths of 36 Ca and 38 Ca

In this work, the $B(E2, 0^+_1 → 2^+_1)$ strengths of 36 Ca and 38 Ca are measured to be 131(20) $e^2\text{fm}^4$ and 101(11) $e^2\text{fm}^4$, respectively. The $\textit{B}(\textit{E}2)$ value for 36 Ca required a measurement of the p/γ branching ratio because the 2 + state is proton unbound. This branching ratio is $B_p$=0.087(8). These $\textit{B}(\textit{E}2)$ and branching-ratio values can be reproduced in the shell-model with the ZMB2 interaction, an interaction that predicts the $\textit{Z} = 20 \textit{sd}$-shell closure is incomplete with large proton pf-shell occupancies in the ground state. These occupancies are at odds with other shell-model and energy-density-functional calculations of 36 Ca. New data are used to provide an update on constraints of the density dependence of the symmetry energy through mirror charge-radii differences as well as to help reduce uncertainties of the astrophysical important 35 K(p,γ) reaction.

73 NUCLEAR PHYSICS AND RADIATION PHYSICS↗

Measurement of the helicity asymmetry $${\mathbb {E}}$$ for the $$\vec {\gamma }\vec {p} \rightarrow p \pi ^0$$ reaction in the resonance region: The CLAS Collaboration

Abstract The double-spin-polarization observable $${\mathbb {E}}$$ E for $$\vec {\gamma }\vec {p}\rightarrow p\pi ^0$$ γ → p → → p π 0 has been measured with the CEBAF Large Acceptance Spectrometer (CLAS) at photon beam energies $$E_\gamma $$ E γ from 0.367 to $$2.173~\textrm{GeV}$$ 2.173 GeV (corresponding to center-of-mass energies from 1.240 to $$2.200~\textrm{GeV}$$ 2.200 GeV ) for pion center-of-mass angles, $$\cos \theta _{\pi ^0}^{c.m.}$$ cos θ π 0 c . m . , between $$-$$ - 0.86 and 0.82. These new CLAS measurements cover a broader energy range and have smaller uncertainties compared to previous CBELSA data and provide an important independent check on systematics. These measurements are compared to predictions as well as new global fits from The George Washington University, Mainz, and Bonn-Gatchina groups. Their inclusion in multipole analyses will allow us to refine our understanding of the single-pion production contribution to the Gerasimov-Drell-Hearn sum rule and improve the determination of resonance properties, which will be presented in a future publication.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗