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Dosimetric commissioning and quality assurance of scanned ion beams at the Italian National Center for Oncological Hadrontherapy

Purpose: To describe the dosimetric commissioning and quality assurance (QA) of the actively scanned proton and carbon ion beams at the Italian National Center for Oncological Hadrontherapy. Methods: The laterally integrated depth-dose-distributions (IDDs) were acquired with the PTW Peakfinder, a variable depth water column, equipped with two Bragg peak ionization chambers. FLUKA Monte Carlo code was used to generate the energy libraries, the IDDs in water, and the fragment spectra for carbon beams. EBT3 films were used for spot size measurements, beam position over the scan field, and homogeneity in 2D-fields. Beam monitor calibration was performed in terms of number of particles per monitor unit using both a Farmer-type and an Advanced Markus ionization chamber. The beam position at the isocenter, beam monitor calibration curve, dose constancy in the center of the spread-out-Bragg-peak, dose homogeneity in 2D-fields, beam energy, spot size, and spot position over the scan field are all checked on a daily basis for both protons and carbon ions and on all beam lines. Results: The simulated IDDs showed an excellent agreement with the measured experimental curves. The measured full width at half maximum (FWHM) of the pencil beam in air at the isocenter was energy-dependent for both particle species: in particular, for protons, the spot size ranged from 0.7 to 2.2 cm. For carbon ions, two sets of spot size are available: FWHM ranged from 0.4 to 0.8 cm (for the smaller spot size) and from 0.8 to 1.1 cm (for the larger one). The spot position was accurate to within ±1 mm over the whole 20 × 20 cm{sup 2} scan field; homogeneity in a uniform squared field was within ±5% for both particle types at any energy. QA results exceeding tolerance levels were rarely found. In the reporting period, the machine downtime was around 6%, of which 4.5% was due to planned maintenance shutdowns. Conclusions: After successful dosimetric beam commissioning, quality assurance measurements performed during a 24-month period show very stable beam characteristics, which are therefore suitable for performing safe and accurate patient treatments.

60 APPLIED LIFE SCIENCES↗

Polarized proton beam for eRHIC

RHIC has provided polarized proton collisions from 31 GeV to 255 GeV in the past decade. To preserve polarization through numerous depolarizing resonances through the whole accelerator chain, harmonic orbit correction, partial snakes, horizontal tune jump system and full snakes have been used. In addition, close attentions have been paid to betatron tune control, orbit control and beam line alignment. The polarization of 60% at 255 GeV has been delivered to experiments with 1.8×10 11 bunch intensity. For the eRHIC era, the beam brightness has to be maintained to reach the desired luminosity. Since we only have one hadron ring in the eRHIC era, existing spin rotator and snakes can be converted to six snake configuration for one hadron ring. With properly arranged six snakes, the polarization can be maintained at 70% at 250 GeV. This paper summarizes the effort and plan to reach high polarization with small emittance for eRHIC.

43 PARTICLE ACCELERATORS↗

Search for short-baseline oscillations at the NOvA Near Detector

Anomalous results from past neutrino experiments have been interpreted as potential evidence for an additional sterile neutrino with a mass on order of 1 eV, but this evidence remains inconclusive. The NOvA Near Detector is a 300 ton almost fully-active fine- grained liquid scintillator detector, that was designed for electron-neutrino identification. The detector is placed along the Fermilab NuMI beam line 1 km from the target and 14.6 mrad off-axis. At this off-axis angle the detector is exposed to a narrow band beam peaked at 2 GeV. Therefore the NOvA Near Detector will see neutrinos with a L/E range that is sensitive to oscillations between active neutrinos and light sterile neutrinos. In this report we discuss NOvA sensitivity from the joint electron-neutrino disappearance and muon-neutrino disappearance analysis search for short-baseline sterile neutrino mixing.

43 PARTICLE ACCELERATORS↗

Technological developments and accelerator improvements for the FRIB beam power ramp-up

The Facility for Rare Isotope Beams (FRIB) began operation with 1 kW beam power for scientific users in May 2022 upon completion of 8 years of project construction. The ramp-up to the ultimate beam power of 400 kW, planned over a 6-year period, will enable the facility to reach its full potential for scientific discovery in isotope science and applications. In December 2023, a record-high beam power of 10.4 kW uranium was delivered to the target. Technological developments and accelerator improvements are being made over the entire facility and are key to completion of the power ramp-up. Major technological developments entail the phased deployment of high-power beam-intercepting systems, including the charge strippers, the charge selection systems, the production target, and the beam dump, along with support systems, including non-conventional utilities (NCU) and remote handling facilities. Major accelerator improvements include renovations to aging legacy systems associated with experimental beam lines and system automation for improved operational efficiency and better machine availability. Experience must be gained to safely handle the increased radiological impacts associated with high beam power; extensive machine studies and advanced beam tuning procedures are needed to minimize uncontrolled beam losses for the desired operating conditions. This paper discusses the technological developments and accelerator improvements with emphasis on major R&D efforts.

43 PARTICLE ACCELERATORS↗

A 500 KV INVERTED GEOEMTRY FEEDTHROUGH FOR A HIGH VOLT-AGE DC ELECTRON GUN

The Continuous Electron Beam Accelerator Facility injector at Jefferson Lab (JLab) utilizes an inverted-geometry ceramic insulator photogun operating at 130 kV direct current to generate spin-polarized electron beams for high-energy nuclear physics experiments. A second photogun delivers 180 keV beam for commissioning a SRF booster in a testbed accelerator, and a larger version delivers 300 keV magnetized beam in a test stand beam line. This contribution reports on the development of an unprecedented inverted-insulator with cable connector for reliably applying 500 kV DC to a future polarized beam photogun, to be designed for operating at 350 kV without field emission. Such a photogun design could then be used for generating a polarized electron beam to drive a spin-polarized positron source as a demonstrator for high energy nuclear physics at JLab. There are no commercial cable connectors that fit the large inverted insulators required for that voltage range. Our proposed concept is based on a modified epoxy receptacle with intervening SF6 layer and a test electrode in a vacuum vessel.

Hernandez-Garcia, C.↗

High Energy Micron Scale Pixel Hybrid Detector

The objective of this technology development project has been to fabricate and characterize a new X-ray area image sensor innovation designed for high efficiency detection and imaging of hard X-rays (>20 KeV) with micron scale pixel resolution. A key technology component consists of a monolithic hybrid X-ray detector built by layering an amorphous Selenium X-ray photoconductor film directly deposited on a small pitch (7.8μm) CMOS active pixel readout array. A specific goal of this work is to provide a new detector tool to researchers working with synchrotron light sources, to extend the depth of exploration into nanoscale structures, and do so cost effectively. Early generation X-ray imaging detector tools fail to provide adequate resolving power and efficiency at high energies and our innovation provides a solution. A majority of proposed phase I tasks were completed. Those tasks included, in collaboration with KA Imaging, successful fabrication of specified a-Se layers on a 1Mpixel CMOS readout array to create the direct hybrid X-ray imaging array, packaging of the imaging array, assembly of electronics into a shielded detector box, loading user interface software for camera control and image capture, and performing initial (no X-ray) detector evaluation at Farrier Microengineering facilities. After initial tests, extensive testing using the X-ray beam line 1-BM source at Argonne National Laboratory Advanced Photon Source(ANL-APS) was performed. Imaging performance studies were conducted at multiple X-ray beam energies. Studies included X-ray response vs. X-ray energy, vs. applied detector field strength (HV), response linearity vs. integration time, MTF vs. beam energy, image lag measurements, and micron scale resolution pattern target imaging. This high energy micron scale X-ray detection technology is a first of a kind to be evaluated at the ANL-APS and is supported by Dr. Antonino Miceli, head of the detector physics group. Accomplishments include the first successful demonstration of a 1Mpix amorphous Selenium on CMOS readout direct hybrid X-ray imaging detector at a DOE sponsored National Laboratory. Modeled performance predictions were confirmed, proving micron scale resolution as well as an order of magnitude increase in conversion efficiency over conventional scintillator detector performance. A discovery of evidence of propagation-based phase contrast edge enhancement was unplanned and will be exploited in future experiments. This phase 1 technology demonstration verifies the efficacy of proposed high energy micron scale pixel X-ray hybrid a-Se imaging array products. The new detector products will cost effectively replace early generation detector technologies that currently fail to address increasing demand for tools to study nano structures and physical processes at high X-ray energies above 20keV. For example, current systems for transmission X-ray microscopy have low efficiency and available large pixel (~55µm) direct detectors do not offer sufficient resolution for Bragg fringe imaging at high energies. This detector innovation will solve these inadequacies. The new detector technology will compete in a $50M scientific X-ray detector market, growing at 6%, and will benefit Microtomography(µCT), X-ray diffractometry (XRD), Coherent Diffraction Imaging (CDI) applications. One application specified by Dr. Miceli at ANL is the 3D reconstruction of compact crystals at high energies requires small pixel high efficiency X-ray detectors. Farrier Microengineering, working with colleagues at KA Imaging and the University of Waterloo, successfully achieved the critical objectives of the Phase I proposal. We have proven the technical feasibility of this innovation by building and successfully testing a 1Mpixel a-Se/CMOS hybrid direct X-ray imaging array. Our commercialization roadmap of detector products will be implemented during a phase II project. We will demonstrate a migration of the technology to larger detector array sizes, improved temporal performance with detector layer engineering, and improved environmental and operational stability. Manufacturability and cost effectiveness are key objectives and product designs will leverage current state of the art CMOS wafer fabrication quality and volume manufacturing economics.

36 MATERIALS SCIENCE↗

Synchrotron Light Options at Super-B

Super-B is a planned asymmetric high luminosity e{sup +}e{sup -} collider at the {Upsilon}(4S) resonance as PEP-II and KEKB, to be built in Italy. The Super-B High (HER, 7 GeV) and Low (LER, 4 GeV) Energy beams characteristics are comparable to NSLS-II and other state of the art synchrotron light sources. This suggests the use of this facility, either parasitically or in dedicated runs, as light source. In this paper we compare the characteristics of the synchrotron light generated at Super-B with existing, in construction and proposed facilities. We investigate different schemes to incorporate the generation of synchrotron radiation in the collider lattice design and look at different beam line layouts for users. In the past high energy particle colliders were designed to collide as many particle as possible. This was done by maximizing the beam current, using relative large emittances and squeezing the beam at the interaction point. During the operation of PEP II the limits of both raising the beam currents and squeezing the beam were experienced. Therefore the optics was modified to lower emittance. The successful test of the 'large Piwinski angle' and crab waist scheme, with extremely low design emittances, at the DAPHNE collider at Frascati made it the design choice for Super-B. Both HER and LER have been designed to meet these requirements and the design parameters relevant to our study, are shown in Table 1. As comparison the design parameters from NSLS II and other state of the art synchrotron light sources have been added to this table. From these parameters it is obvious that synchrotron radiation generated from both HER and LER is comparable to this last generation sources.

43 PARTICLE ACCELERATORS↗

Radiological Consequences of Beam Loss at Front End by FLUKA during Top-off Injection into the Storage Ring for PROJECT Beamlines

NSLS-II plans to run the top-off mode operation in the near future. Particle tracking simulations proved that an errant injected electron beam can be confined to the beam-line frontend inside the storage ring tunnel by use of appropriate apertures and interlocks. Photon shutter collimator 2 (C2) was selected as the safe point (i.e. electron beam can’t travel beyond the safe point). FLUKA simulations have been carried out with the current beamline front ends and ratchet wall configurations to independently verify the previous calculations performed [1].

36 MATERIALS SCIENCE↗

Low energy beam transport for facility for rare isotope beams driver linear particle accelerator

The driver linac for the facility for rare isotope beams (FRIB) will provide a wide range of primary ion beams for nuclear physics research. The linac will be capable of accelerating a uranium beam to an energy of up to 200 Mev/u and delivering it to a fragmentation target with a maximum power of 400 kW. Stable ion beams will be produced by a high performance electron cyclotron resonance ion source operating at 28 GHz. The ion source will be located on a high voltage platform to reach an initial beam energy of 12 keV/u. After extraction, the ion beam will be transported vertically down to the linac tunnel in a low energy beam transport (LEBT) system and injected into a radio frequency quadrupole (RFQ) operating at a frequency of 80.5 MHz. To meet the beam power requirements, simultaneous acceleration of two-charge states will be used for heavier ions ({>=}Xe). This paper presents the layout of the FRIB LEBT and the beam dynamics in the LEBT. In particular, simulation and design of the beam line section before charge state selection will be detailed. The need to use an achromatic design for the charge state selection system and the advantage of an ion beam collimation system to limit the emittance of the beam injected into the RFQ will be discussed in this paper.

43 PARTICLE ACCELERATORS↗

An extraction scheme for future CEBAF FFA based energy upgrade

Jefferson lab is considering an energy increase from current 12 GeV to 22 GeV for its CEBAF accelerator. This will be accomplished by recirculating 5-6 additional turns through two parallel CEBAF LINACs using an FFA arc at each end of the racetrack. The total recirculation turns would be 10 times, the first four turns use present conventional arcs to make the 180-degree bends from one LINAC to the other. However, the last 5-6 turns will all share a single beam line inside two FFA arcs. This reduces the footprint and the cost of the project significantly. On the other hand, having the trajectories of last 5-6 recirculating beams close to each other makes it challenging to extract beams from different passes with different energies. In this paper we will explain our present extraction system for 12 GeV, our challenges and limitations, and a possible extraction solution for the 22 GeV upgrade with the goal of extracting beam at different turns/energies to different experimental halls.

Accelerator Physics↗

Beam Pipe HOM Absorber for 750 MHz RF Cavity Systems

This joint project of Muons, Inc., Cornell University and SLAC was supported by a Phase I and Phase II grant monitored by the SBIR Office of Science of the DOE. Beam line HOM absorbers are a critical part of future linear colliders. The use of lossy materials at cryogenic temperatures has been incorporated in several systems. The design in beam pipes requires cylinders of lossy material mechanically confined in such a way as to absorb the microwave energy from the higher-order modes and remove the heat generated in the lossy material. Furthermore, the potential for charge build-up on the surface of the lossy material requires the conductivity of the material to remain consistent from room temperature to cryogenic temperatures. In this program a mechanical design was developed that solved several design constraints: a) fitting into the existing Cornell load vacuum component, b) allowing the use of different material compositions, c) a thermal design that relied upon the compression of the lossy ceramic material without adding stress. Coating experiments were performed that indicated the design constraints needed to fully implement this approach for solving the charge build-up problem inherent in using lossy ceramics. In addition, the ACE3P program, used to calculate the performance of lossy cylinders in beam pipes in general, was supported by this project. Code development and documentation to allow for the more wide spread use of the program was a direct result of this project was well.

43 PARTICLE ACCELERATORS↗

Extraction scheme for future CEBAF FFA based energy upgrade

Jefferson lab is considering an energy increase from current 12 GeV to 22 GeV for its CEBAF accelerator. This will be accomplished by recirculating 5-6 additional turns through two parallel CEBAF LINACs using an FFA arc at each end of the racetrack. The total recirculation turns would be 10 times, the first four turns use present conventional arcs to make the 180-degree bends from one LINAC to the other. However, the last 5-6 turns will all share a single beam line inside two FFA arcs. This reduces the footprint and the cost of the project significantly. On the other hand, having the trajectories of last 5-6 recirculating beams close to each other makes it challenging to extract beams from different passes with different energies. In this paper we will explain our present extraction system for 12 GeV, our challenges and limitations, and a possible extraction solution for the 22 GeV upgrade with the goal of extracting beam at different turns/energies to different experimental halls.

Kazimi, Reza↗

Gamma ray facilities at the University of Maryland cyclotron

A special beam line was set up in a separate shielded experimental room to provide a low background station for gamma-ray measurements at the University of Maryland cyclotron. The transmitted beam leaving the target is gathered in by a magnetic quadrupole lens located 1.8 m further downstream and focused on a Faraday cup located on the far side of the 2.5 m thick concrete shielding wall of the experimental room. A software computer program permits timing information ot be obtained using the cyclotron beam fine structure as a time reference for the observed gamma-ray events. Measurements indicate a beam fine structure width of less than 1.2 nanoseconds repeated, for example, in the case of 140 MeV alpha particles every 90 nanoseconds. Twelve contiguous time channels of adjustable width may be set as desired with reference to the RF signal. This allows the creation of 12 separate 8192 channel analyzers.

Hornyak, W. F.↗

Measurement of the surface profile of a curved optical surface with rotation phase-shifting lateral shear cyclic path optical configuration

We present a new (to our knowledge) technique for introducing phase shifts between the laterally sheared emergent beam components of a cyclic path optical configuration (CPOC). The phase shifts are introduced by applying a small change in the angle of incidence of the incident beam due to the small angular rotation of the CPOC setup. Phase-shifting interferometry has been applied along with this phase-shifting technique for a CPOC with lateral shear to find the surface slope/profile of curved optical surfaces. Results for a spherical optical surface have been discussed. An optical setup for measurement of the surface profile of toroidal beam line mirrors of synchrotron radiation sources is proposed.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗

Optimization of AC Dipole Parameters for the Mu2e Extinction System

The Mu2e experiment is being planned at Fermilab to measure the rate for muons to convert to electrons in the field of an atomic nucleus with unprecedented precision. This experiment uses an 8 GeV primary proton beam consisting of short ({approx}200 nsec FW) bunches, separated by 1.7 {mu}sec. It is vital that out-of-bunch beam be suppressed at the level of 10{sup -10} or less. This poster describes the parametric analysis which was done to determine the optimum harmonics and magnet specifications for this system, as well as the implications for the beam line optics.

43 PARTICLE ACCELERATORS↗

Geant4 simulations on Compton scattering of laser photons on relativistic electrons

Using Geant4, a complex simulation code of the interaction between laser photons and relativistic electrons was developed. We implemented physically constrained electron beam emittance and spacial distribution parameters and we also considered a Gaussian laser beam. The code was tested against experimental data produced at the γ-ray beam line GACKO (Gamma Collaboration Hutch of Konan University) of the synchrotron radiation facility NewSUBARU. Here we will discuss the implications of transverse missallignments of the collimation system relative to the electron beam axis.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗

WE-EF-303-06: Feasibility of PET Image-Based On-Line Proton Beam-Range Verification with Simulated Uniform Phantom and Human Brain Studies

Purpose: To study the feasibility of clinical on-line proton beam range verification with PET imaging Methods: We simulated a 179.2-MeV proton beam with 5-mm diameter irradiating a PMMA phantom of human brain size, which was then imaged by a brain PET with 300*300*100-mm{sup 3} FOV and different system sensitivities and spatial resolutions. We calculated the mean and standard deviation of positron activity range (AR) from reconstructed PET images, with respect to different data acquisition times (from 5 sec to 300 sec with 5-sec step). We also developed a technique, “Smoothed Maximum Value (SMV)”, to improve AR measurement under a given dose. Furthermore, we simulated a human brain irradiated by a 110-MeV proton beam of 50-mm diameter with 0.3-Gy dose at Bragg peak and imaged by the above PET system with 40% system sensitivity at the center of FOV and 1.7-mm spatial resolution. Results: MC Simulations on the PMMA phantom showed that, regardless of PET system sensitivities and spatial resolutions, the accuracy and precision of AR were proportional to the reciprocal of the square root of image count if image smoothing was not applied. With image smoothing or SMV method, the accuracy and precision could be substantially improved. For a cylindrical PMMA phantom (200 mm diameter and 290 mm long), the accuracy and precision of AR measurement could reach 1.0 and 1.7 mm, with 100-sec data acquired by the brain PET. The study with a human brain showed it was feasible to achieve sub-millimeter accuracy and precision of AR measurement with acquisition time within 60 sec. Conclusion: This study established the relationship between count statistics and the accuracy and precision of activity-range verification. It showed the feasibility of clinical on-line BR verification with high-performance PET systems and improved AR measurement techniques. Cancer Prevention and Research Institute of Texas grant RP120326, NIH grant R21CA187717, The Cancer Center Support (Core) Grant CA016672 to MD Anderson Cancer Center.

60 APPLIED LIFE SCIENCES↗

Laser-assisted high-energy proton pulse extraction for feasibility study of co-located muon source at the SNS

Here, we have experimentally demonstrated the first non-intrusive 1-GeV proton beam extraction for the generation of muons with a temporal structure optimized for Muon Spin Relaxation/Rotation/Resonance (μSR) applications. The proton pulses are extracted based on the laser neutralization of 1 GeV hydrogen ion (H - ) beam in the high energy beam transport of the Spallation Neutron Source (SNS) accelerator. The maximum flux of the extracted proton beam based on laser neutralization causes only 0.2% reduction of the total proton beam used for neutron production, a marked difference from the 20% reduction at other co-located muon and neutron facilities, and thus the proposed method will result in negligible impact on the SNS operation. This paper describes the development of a fiber/solid-state hybrid laser system that has high flexibility of pulse structure and output power, initial experiments on laser neutralization of beam and separation of H 0 beam from the existing SNS accelerator beam line, conversion of H 0 to proton at the SNS linac dump, and measurement results of 30 ns/50 kHz proton pulses. This system conclusively demonstrates the feasibility of laser-based proton beam extraction to power a world-leading μSR facility at the SNS.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗