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At least 361 records · Page 20

Accuracy of a dose-area product compared to an absorbed dose to water at a point in a 2 cm diameter field

Purpose: Graphite calorimeters with a core diameter larger than the beam can be used to establish dosimetric references in small fields. The dose-area product (DAP) measured can theoretically be linked to an absorbed dose at a point by the determination of a profile correction. This study aims at comparing the DAP-based protocol to the usual absorbed dose at a point protocol in a 2 cm diameter field for which both references exist. Methods: Two calorimeters were used, respectively, with a sensitive volume of 0.6 cm (for the absorbed dose at a point measurement) and 3 cm diameter (for the DAP measurement). Profile correction was calculated from a 2D dose mapping using three detectors: a PinPoint chamber, a synthetic diamond, and EBT3 films. A specific protocol to read EBT3 films was implemented and the dose-rate and energy dependences were studied to assure a precise measurement, especially in the penumbra and out-of-field regions. Results: EBT3 films were found independent on dose rates over the range studied but showed a strong under-response (18%) at low energies. Depending on the dosimeter used for calculating the profile correction, a deviation of 0.8% (PinPoint chamber), 0.9% (diamond), or 1.9% (EBT3 films) was observed between the calibration coefficient derived from DAP measurements and the one directly established in terms of absorbed dose to water at a point. Conclusions: The DAP method can currently be linked to the classical dosimetric reference system based in an absorbed dose at a point only with a confidence interval of 95% (k = 2). None of the detectors studied can be used to determine an absorbed dose to water at a point from a DAP measurement with an uncertainty smaller than 1.2%.

60 APPLIED LIFE SCIENCES↗

SU-F-T-14: Dosimetric Impacts of Various Uncertainties in Cervical Cancer HDR Brachytherapy: Are Conventional Point Doses Good Surrogates for 3D Dosimetry?

Purpose: In the context of evaluating dosimetric impacts of a variety of uncertainties involved in HDR Tandem-and-Ovoid treatment, to study the correlations between conventional point doses and 3D volumetric doses. Methods: For 5 cervical cancer patients treated with HDR T&O, 150 plans were retrospectively created to study dosimetric impacts of the following uncertainties: (1) inter-fractional applicator displacement between two treatment fractions within a single insertion by applying Fraction#1 plan to Fraction#2 CT; (2) positional dwell error simulated from −5mm to 5mm in 1mm steps; (3) simulated temporal dwell error of 0.05s, 0.1s, 0.5s, and 1s. The original plans were based on point dose prescription, from which the volume covered by the prescription dose was generated as the pseudo target volume to study the 3D target dose effect. OARs were contoured. The point and volumetric dose errors were calculated by taking the differences between original and simulated plans. The correlations between the point and volumetric dose errors were analyzed. Results: For the most clinically relevant positional dwell uncertainty of 1mm, temporal uncertainty of 0.05s, and inter-fractional applicator displacement within the same insertion, the mean target D90 and V100 deviation were within 1%. Among these uncertainties, the applicator displacement showed the largest potential target coverage impact (2.6% on D90) as well as the OAR dose impact (2.5% and 3.4% on bladder D2cc and rectum D2cc). The Spearman correlation analysis shows a correlation coefficient of 0.43 with a p-value of 0.11 between target D90 coverage and H point dose. Conclusion: With the most clinically relevant positional and temporal dwell uncertainties and patient interfractional applicator displacement within the same insertion, the dose error is within clinical acceptable range. The lack of correlation between H point and 3D volumetric dose errors is a motivator for the use of 3D treatment planning in cervical HDR brachytherapy.

60 APPLIED LIFE SCIENCES↗

SU-F-T-36: Dosimetric Comparison of Point Based Vs. Target Based Prescription for Intracavitary Brachytherapy in Cancer of the Cervix

Purpose: Improved patient imaging used for planning the treatment of cervical cancer with Tandem and Ovoid (T&O) Intracavitary high-dose-rate brachytherapy (HDR) now allows for 3D delineation of target volumes and organs-at-risk. However, historical data relies on the conventional point A-based planning technique. A comparative dosimetric study was performed by generating both target-based (TBP) and point-based (PBP) plans for ten clinical patients. Methods: Treatment plans created using Elekta Oncentra v. 4.3 for ten consecutive cervical cancer patients were analyzed. All patients were treated with HDR using the Utrecht T&O applicator. Both CT and MRI imaging modalities were utilized to delineate clinical target volume (CTV) and organs-at-risk (rectum, sigmoid, bladder, and small bowel). Point A (left and right), vaginal mucosa, and ICRU rectum and bladder points were defined on CT. Two plans were generated for each patient using two prescription methods (PBP and TBP). 7Gy was prescribed to each point A for each PBP plan and to the target D90% for each TBP plan. Target V90%, V100%, and V200% were evaluated. In addition, D0.1cc and D2cc were analyzed for each organ-at-risk. Differences were assessed for statistical significance (p<0.05) by use of Student’s t-test. Results: Target coverage was comparable for both planning methods, with each method providing adequate target coverage. TBP showed lower absolute dose to the target volume than PBP (D90% = 7.0Gy vs. 7.4Gy, p=0.028), (V200% = 10.9cc vs. 12.8cc, p=0.014), (ALeft = 6.4Gy vs. 7Gy, p=0.009), and (ARight = 6.4Gy vs. 7Gy, p=0.013). TBP also showed a statistically significant reduction in bladder, rectum, small bowel, and sigmoid doses compared to PBP. There was no statistically significant difference in vaginal mucosa or ICRU-defined rectum and bladder dose. Conclusion: Target based prescription resulted in substantially lower dose to delineated organs-at-risk compared to point based prescription, while maintaining similar target coverage.

60 APPLIED LIFE SCIENCES↗

Spin Berry points as crucial for ultrafast demagnetization

Laser-induced ultrafast demagnetization has puzzled researchers around the world for over two decades. Intrinsic complexity in electronic, magnetic and phononic subsystems is difficult to understand microscopically. So far, it is not possible to explain demagnetization using a single mechanism, which suggests a crucial piece of information still missing. In this paper, we return to a fundamental aspect of physics: spin and its change within each band in the entire Brillouin zone. We employ face-centered cubic (fcc) Ni as an example and use an extremely dense k mesh to map out spin changes for every band close to the Fermi level along all the high symmetry lines. To our surprise, spin angular momentum at some special k points abruptly changes from [Formula: see text] to [Formula: see text] simply by moving from one crystal momentum point to the next. This explains why intraband transitions, which the spin superdiffusion model is based upon, can induce a sharp spin moment reduction, and why electric current can change spin orientation in spintronics. These special k points, which are called spin Berry points [M. V. Berry, Proc. R. Soc. Lond. A 393 (1984) 45], are not random and appear when several bands are close to each other, so the Berry potential of spin majority states is different from that of spin minority states. Although within a single band, spin Berry points jump, when we group several neighboring bands together, they form distinctive smooth spin Berry lines. It is the band structure that disrupts those lines. Spin Berry points are crucial to laser-induced ultrafast demagnetization and spintronics.

Physics↗

Coincidence of the Measured Voltage Peak and the Measured Current Inflection Point in Exploding Metals

Exploding Bridgewire (EBW) Detonators and Exploding Foil Initiators (EFI's, e.g. Slappers) have unique current and voltage characteristics marked by a large voltage spike and an inflection point in the current. Mathematically, it is shown that the voltage peak and the current inflection point must align in time. Models concur with the math and show voltage peaks occurring at the same point in time as the inflection point. Circuit analysis is performed to demonstrate why the voltage peak and current inflection point will almost never align in time for an experiment. To correctly analyze exploding metal behavior, the current inflection point and voltage peak must be manually aligned in time. These conclusions apply to single detonators where current and voltage is measured on those detonators. In multi-detonator systems, the conclusions herein apply only for cases where current and voltage are obtained for each detonator individually. The conclusions will begin to break down as measurements become combined.

36 MATERIALS SCIENCE↗

Deep learning models for interpretation of point of care ultrasound in military working dogs

Introduction: Military working dogs (MWDs) are essential for military operations in a wide range of missions. With this pivotal role, MWDs can become casualties requiring specialized veterinary care that may not always be available far forward on the battlefield. Some injuries such as pneumothorax, hemothorax, or abdominal hemorrhage can be diagnosed using point of care ultrasound (POCUS) such as the Global FAST® exam. This presents a unique opportunity for artificial intelligence (AI) to aid in the interpretation of ultrasound images. In this article, deep learning classification neural networks were developed for POCUS assessment in MWDs. Methods: Images were collected in five MWDs under general anesthesia or deep sedation for all scan points in the Global FAST® exam. For representative injuries, a cadaver model was used from which positive and negative injury images were captured. A total of 327 ultrasound clips were captured and split across scan points for training three different AI network architectures: MobileNetV2, DarkNet-19, and ShrapML. Gradient class activation mapping (GradCAM) overlays were generated for representative images to better explain AI predictions. Results: Performance of AI models reached over 82% accuracy for all scan points. The model with the highest performance was trained with the MobileNetV2 network for the cystocolic scan point achieving 99.8% accuracy. Across all trained networks the diaphragmatic hepatorenal scan point had the best overall performance. However, GradCAM overlays showed that the models with highest accuracy, like MobileNetV2, were not always identifying relevant features. Conversely, the GradCAM heatmaps for ShrapML show general agreement with regions most indicative of fluid accumulation. Discussion: Overall, the AI models developed can automate POCUS predictions in MWDs. Preliminarily, ShrapML had the strongest performance and prediction rate paired with accurately tracking fluid accumulation sites, making it the most suitable option for eventual real-time deployment with ultrasound systems. Further integration of this technology with imaging technologies will expand use of POCUS-based triage of MWDs.

59 BASIC BIOLOGICAL SCIENCES↗

Space Shuttle Earth Observation sensors pointing and stabilization requirements study

The shuttle orbiter inertial measurement unit (IMU), located in the orbiter cabin, is used to supply inertial attitude reference signals; and, in conjunction with the onboard navigation system, can provide a pointing capability of the navigation base accurate to within plus or minus 0.5 deg for earth viewing missions. This pointing accuracy can degrade to approximately plus or minus 2.0 deg for payloads located in the aft bay due to structural flexure of the shuttle vehicle, payload structural and mounting misalignments, and calibration errors with respect to the navigation base. Drawbacks to obtaining pointing accuracy by using the orbiter RCS jets are discussed. Supplemental electromechanical pointing systems are developed to provide independent pointing for individual sensors, or sensor groupings. The missions considered and the sensors required for these missions and the parameters of each sensor are described. Assumptions made to derive pointing and stabilization requirements are delineated.

Source record↗

Magnetic suspension and pointing system

An apparatus is reported for accurate pointing of instruments on a carrier vehicle and for isolation of the instruments from the vehicle's motion disturbances. The apparatus includes two assemblies with connecting interfaces. The first assembly is attached to the carrier vehicle and consists of an azimuth gimbal and an elevation gimbal which provide coarse pointing by allowing two rotations of the instruments relative to the carrier vehicle. The second or vernier pointing assembly is made up of magnetic suspension and fine pointing actuators, roll motor segments, and an instrument mounting plase which provides appropriate magnetic circuits for the actuators and the roll motor segments. The vernier pointing assembly provides attitude fine pointing and roll positioning of the instruments as well as six degree-of-freedom isolation from carrier motion disturbances.

Anderson, W. W.↗

The Annular Suspension and Pointing System

The Annular Suspension and Pointing System (ASPS) is a general purpose mount designed to provide orientation, mechanical isolation, and fine pointing for space experiments. The ASPS consists of two assemblies, the first being a set of two gimbals attached to a carrier spacecraft (e.g., Space Shuttle) and providing coarse pointing, and the second a magnetic vernier pointing and isolation assembly attached to the inner gimbal of the first assembly and providing fine pointing. Discussion of the evolution of this concept, required related technology, and data from analyses and simulations predicting pointing accuracies that allowed the specification of hardware design requirements is presented.

Anderson, W. W.↗

The Use of Principal Components for Creating Improved Imagery for Geometric Control Point Selection

A directed principal component (PC) analysis and its transformation was applied to 7-channel thematic mapper simulator (TMS) data and 4-channel LANDSAT multispectral scanner system (MSS) data collected over the city of Lancaster, Pennsylvania, to create improved imagery for geometric control point selection for image to image registration. Nineteen temporally stable geometric control points, such as road interactions and bridges, were selected for a 236 sq km area. The control points were visible on both the TMS and MSS imagery. On the first attempt the corresponding image control points were selected on both data sets without using the principal components transformation. Many of the road intersection locations were visible but the actual road crossings could not be distinguished. As a result, mensuration errors using raw data exceeded the equivalent of two (79 x 79 m) pixels. The application of a guided principal components transformation yielded TMS and MSS single band images showing improved detail in the scene's urban and residential infrastructure. The PC transformed data sets were then utilized for the reselection of geometric control points. By shown greater detail, control points on both the TMS and MSS imagery could be located with greater precision using the PC transformed data.

Imhoff, M. L.↗

Experimental results for the rapid determination of the freezing point of fuels

Two methods for the rapid determination of the freezing point of fuels were investigated: an optical method, which detected the change in light transmission from the disappearance of solid particles in the melted fuel; and a differential thermal analysis (DTA) method, which sensed the latent heat of fusion. A laboratory apparatus was fabricated to test the two methods. Cooling was done by thermoelectric modules using an ice-water bath as a heat sink. The DTA method was later modified to eliminate the reference fuel. The data from the sample were digitized and a point of inflection, which corresponds to the ASTM D-2386 freezing point (final melting point), was identified from the derivative. The apparatus was modifified to cool the fuel to -60 C and controls were added for maintaining constant cooling rate, rewarming rate, and hold time at minimum temperature. A parametric series of tests were run for twelve fuels with freezing points from -10 C to -50 C, varying cooling rate, rewarming rate, and hold time. Based on the results, an optimum test procedure was established. The results showed good agreement with ASTM D-2386 freezing point and differential scanning calorimetry results.

Mathiprakasam, B.↗

Impact of magnetic isolation on pointing system performance in the presence of structural flexibility

The inertial pointing stability of a gimbal pointing system (AGS) was compared with a magnetic pointing/gimbal followup system (ASPS), under certain conditions of system structural flexibility and disturbance inputs from the gimbal support structure. Separate 3 degree-of-freedom (3DOF) linear models based on NASTRAN modal flexibility data for the gimbal and support structures were generated for the ASPS configurations. Using the models inertial pointing control loops providing 6dB of gain margin and 45 deg of phase margin were defined for each configuration. The pointing loop bandwidth obtained for the ASPS is more than twice the level achieved for the AGS configuration. The AGS limit is attributed to the gimbal and support structure flexibility. As a result of the higher ASPS pointing loop bandwidth and the disturbance rejection provided by the magnetic isolation ASPS pointing performane is significantly better than that of the AGS system. The low frequency peak of the ASPS transfer function from base disturbance to payload angular motion is almost 60dB lower than AGS low frequency peak.

Seller, J.↗

Earth observing system instrument pointing control modeling for polar orbiting platforms

An approach to instrument pointing control performance assessment for large multi-instrument platforms is described. First, instrument pointing requirements and reference platform control systems for the Eos Polar Platforms are reviewed. Performance modeling tools including NASTRAN models of two large platforms, a modal selection procedure utilizing a balanced realization method, and reduced order platform models with core and instrument pointing control loops added are then described. Time history simulations of instrument pointing and stability performance in response to commanded slewing of adjacent instruments demonstrates the limits of tolerable slew activity. Simplified models of rigid body responses are also developed for comparison. Instrument pointing control methods required in addition to the core platform control system to meet instrument pointing requirements are considered.

Briggs, H. C.↗

Minimum-time pointing control of a two-link manipulator

Minimum-time pointing control for the end-effector of a planar, two-link manipulator is developed. Minimum-time pointing control is a new area of research for multilink manipulators, which can be applied to rapid retargeting control of a multibody spacecraft. The minimum-time control problem of aligning the second link of the two-link manipulator with a given target point is considered. A numerical method called the minimizing-boundary-condition method is used to determine optimal solutions for the two-point boundary-value problem associated with first-order necessary conditions. Minimum-time solutions for different models of pointing systems are compared. The results of the comparison show that a two-link manipulator with two degree-of-freedom performs better than a conventional one-link system for minimum-time pointing.

Wie, Bong↗

Precision pointing compensation for DSN antennas with optical distance measuring sensors

The pointing control loops of Deep Space Network (DSN) antennas do not account for unmodeled deflections of the primary and secondary reflectors. As a result, structural distortions due to unpredictable environmental loads can result in uncompensated boresight shifts which degrade pointing accuracy. The design proposed here can provide real-time bias commands to the pointing control system to compensate for environmental effects on pointing performance. The bias commands can be computed in real time from optically measured deflections at a number of points on the primary and secondary reflectors. Computer simulations with a reduced-order finite-element model of a DSN antenna validate the concept and lead to a proposed design by which a ten-to-one reduction in pointing uncertainty can be achieved under nominal uncertainty conditions.

Scheid, R. E.↗

Analysis of the flight dynamics of the Solar Maximum Mission (SMM) off-sun scientific pointing

Algorithms are presented which were created and implemented by the Goddard Space Flight Center's (GSFC's) Solar Maximum Mission (SMM) attitude operations team to support large-angle spacecraft pointing at scientific objectives. The mission objective of the post-repair SMM satellite was to study solar phenomena. However, because the scientific instruments, such as the Coronagraph/Polarimeter (CP) and the Hard X ray Burst Spectrometer (HXRBS), were able to view objects other than the Sun, attitude operations support for attitude pointing at large angles from the nominal solar-pointing attitudes was required. Subsequently, attitude support for SMM was provided for scientific objectives such as Comet Halley, Supernova 1987A, Cygnus X-1, and the Crab Nebula. In addition, the analysis was extended to include the reverse problem, computing the right ascension and declination of a body given the off-Sun angles. This analysis led to the computation of the orbits of seven new solar comets seen in the field-of-view (FOV) of the CP. The activities necessary to meet these large-angle attitude-pointing sequences, such as slew sequence planning, viewing-period prediction, and tracking-bias computation are described. Analysis is presented for the computation of maneuvers and pointing parameters relative to the SMM-unique, Sun-centered reference frame. Finally, science data and independent attitude solutions are used to evaluate the large-angle pointing performance.

Pitone, D. S.↗

Application of inertial instruments for DSN antenna pointing and tracking

The feasibility of using inertial instruments to determine the pointing attitude of the NASA Deep Space Network antennas is examined. The objective is to obtain 1 mdeg pointing knowledge in both blind pointing and tracking modes to facilitate operation of the Deep Space Network 70 m antennas at 32 GHz. A measurement system employing accelerometers, an inclinometer, and optical gyroscopes is proposed. The initial pointing attitude is established by determining the direction of the local gravity vector using the accelerometers and the inclinometer, and the Earth's spin axis using the gyroscopes. Pointing during long-term tracking is maintained by integrating the gyroscope rates and augmenting these measurements with knowledge of the local gravity vector. A minimum-variance estimator is used to combine measurements to obtain the antenna pointing attitude. A key feature of the algorithm is its ability to recalibrate accelerometer parameters during operation. A survey of available inertial instrument technologies is also given.

Eldred, D. B.↗

A comparison between bright points in a coronal hole and a quiet-sun region

A comparison is made of the morphological structure and temporal behavior of the emission from coronal bright points in a coronal hole and a quiet region, using data from the Harvard EUV experiment on Skylab. It is found that, in both regions, coronal bright points are located at network boundaries and cover a range of sizes from 10 to 40 in in linear extent. In a given bright pint, the peaks of emission in the six different lines, measured simultaneously through the same instrument slit, are not always cospatial, implying that bright points consist of a complex of small-scale loops at different temperatures. The intensity of bright points in both regions is also characterized by a significant temporal variability in all the wavelengths measured. This variability exhibits no regular periodicity. Yet the ratio of the varying (ac) to the constant (dc) components of the emission, in all the bright points studied, has a local maximum at 1-2 x 10 to the 5th k which coincides with the peak of the radiative loss function, and another local maximum at Mg x (1.4 x 10 to the 6th K). It is found that coronal bright points in a coronal hole or a quiet region are indistinguishable structures, and, therefore, conclude that they are independent of the overlying background corona.

Habbal, Shadia Rifai↗