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At least 361 records · Page 20

Flame Detector

Scientific Instruments, Inc. has now developed a second generation, commercially available instrument to detect flames in hazardous environments, typically refineries, chemical plants and offshore drilling platforms. The Model 74000 detector incorporates a sensing circuit that detects UV radiation in a 100 degree conical field of view extending as far as 250 feet from the instrument. It operates in a bandwidth that makes it virtually 'blind' to solar radiation while affording extremely high sensitivity to ultraviolet flame detection. A 'windowing' technique accurately discriminates between background UV radiation and ultraviolet emitted from an actual flame, hence the user is assured of no false alarms. Model 7410CP is a combination controller and annunciator panel designed to monitor and control as many as 24 flame detectors. *Model 74000 is no longer being manufactured.

Source record↗

Aid for the Visually Impaired

Viewstar is a video system that magnifies and focuses words so partially sighted people can read or type from printed or written copy. Invented by Dr. Leonard Weinstein, a Langley engineer, the device enables Sandra Raven, Weinstein's stepdaughter, who is legally blind, to work as a clerk typist. Weinstein has also developed other magnification systems for individual needs.

Source record↗

Rocket Engine Turbine Blade Surface Pressure Distributions Experiment and Computations

Understanding the unsteady aspects of turbine rotor flow fields is critical to successful future turbine designs. A technology program was conducted at NASA's Marshall Space Flight Center to increase the understanding of unsteady environments for rocket engine turbines. The experimental program involved instrumenting turbine rotor blades with miniature surface mounted high frequency response pressure transducers. The turbine model was then tested to measure the unsteady pressures on the rotor blades. The data obtained from the experimental program is unique in two respects. First, much more unsteady data was obtained (several minutes per set point) than has been possible in the past. Also, an extensive steady performance database existed for the turbine model. This allowed an evaluation of the effect of the on-blade instrumentation on the turbine's performance. A three-dimensional unsteady Navier-Stokes analysis was also used to blindly predict the unsteady flow field in the turbine at the design operating conditions and at +15 degrees relative incidence to the first-stage rotor. The predicted time-averaged and unsteady pressure distributions show good agreement with the experimental data. This unique data set, the lessons learned for acquiring this type of data, and the improvements made to the data analysis and prediction tools are contributing significantly to current Space Launch Initiative turbine airflow test and blade surface pressure prediction efforts.

Hudson, Susan T.↗

Improving Vision

Many people are familiar with the popular science fiction series Star Trek: The Next Generation, a show featuring a blind character named Geordi La Forge, whose visor-like glasses enable him to see. What many people do not know is that a product very similar to Geordi's glasses is available to assist people with vision conditions, and a NASA engineer's expertise contributed to its development. The JORDY(trademark) (Joint Optical Reflective Display) device, designed and manufactured by a privately-held medical device company known as Enhanced Vision, enables people with low vision to read, write, and watch television. Low vision, which includes macular degeneration, diabetic retinopathy, and glaucoma, describes eyesight that is 20/70 or worse, and cannot be fully corrected with conventional glasses.

Source record↗

Microwave Observations of Precipitation and the Atmosphere

This research effort had three elements devoted to improving satellite-derived passive microwave retrievals of precipitation rate: morphological rain-rate retrievals, warm rain retrievals, and extension of a study of geostationary satellite options. The morphological precipitation-rate retrieval method uses for the first time the morphological character of the observed storm microwave spectra. The basic concept involves: 1) retrieval of point rainfall rates using current algorithms, 2) using spatial feature vectors of the observations over segmented multi-pixel storms to estimate the integrated rainfall rate for that storm (cu m/s), and 3) normalization of the point rain-rate retrievals to ensure consistency with the storm-wide retrieval. This work is ongoing, but two key steps have been completed: development of a segmentation algorithm for defining spatial regions corresponding to single storms for purposes of estimation, and reduction of some of the data from NAST-M that will be used to support this research going forward. The warm rain retrieval method involved extension of Aquai/AIRS/AMSU/HSB algorithmic work on cloud water retrievals. The central concept involves the fact that passive microwave cloud water retrievals over approx. 0.4 mm are very likely associated with precipitation. Since glaciated precipitation is generally detected quite successfully using scattering signatures evident in the surface-blind 54- and 183-GHz bands, this new method complements the first by permitting precipitation retrievals of non-glaciated events. The method is most successful over ocean, but has detected non-glaciated convective cells over land, perhaps in their early formative stages. This work will require additional exploration and validation prior to publication. Passive microwave instrument configurations for use in geostationary orbit were studied. They employ parabolic reflectors between 2 and 4 meters in diameter, and frequencies up to approx.430 GHz; this corresponds to nadir spot diameters as small as 10 km.

Staelin, David H.↗

Fitting Flux Ropes to a Global MHD Solution: A Comparison of Techniques

Flux rope fitting (FRF) techniques are an invaluable tool for extracting information about the properties of a subclass of CMEs in the solar wind. However, it has proven difficult to assess their accuracy since the underlying global structure of the CME cannot be independently determined from the data. In contrast, large-scale MHD simulations of CME evolution can provide both a global view as well as localized time series at specific points in space. In this study we apply 5 different fitting techniques to 2 hypothetical time series derived from MHD simulation results. Independent teams performed the analysis of the events in "blind tests", for which no information, other than the time series, was provided. F rom the results, we infer the following: (1) Accuracy decreases markedly with increasingly glancing encounters; (2) Correct identification of the boundaries of the flux rope can be a significant limiter; and (3) Results from techniques that infer global morphology must be viewed with caution. In spite of these limitations, FRF techniques remain a useful tool for describing in situ observations of flux rope CMEs.

Riley, Pete↗

Strain-Gage Loads Calibration Parametric Study

This paper documents a parametric study of various aircraft wing-load test features that affect the quality of the resultant derived shear, bending-moment, and torque strain-gage load equations. The effect of the following on derived strain-gage equation accuracy are compared: single-point loading compared with distributed loading, variation in applied test load magnitude, number of applied load cases, and wing-box-only compared with control-surface loading. The subject of this study is an extensive wing-load calibration test of the Active Aeroelastic Wing F/A-18 airplane. Selected subsets of the available test data were used to derive load equations using the linear regression method. Results show the benefit of distributed loading and the diminishing-return benefits of test load magnitudes and number of load cases. The use of independent check cases as a quality metric for the derived load equations is shown to overcome blind extrapolating beyond the load data used to derive the load equations.

Lokos, William A.↗

Libration Point Navigation Concepts Supporting Exploration Vision

Farquhar described several libration point navigation concepts that would appear to support NASA s current exploration vision. One concept is a Lunar Relay Satellite operating in the vicinity of Earth-Moon L2, providing Earth-to-lunar far-side and long- range surface-to-surface navigation and communications capability. Reference [ 1] lists several advantages of such a system in comparison to a lunar orbiting relay satellite constellation. Among these are one or two vs. many satellites for coverage, simplified acquisition and tracking due to very low relative motion, much longer contact times, and simpler antenna pointing. An obvious additional advantage of such a system is that uninterrupted links to Earth avoid performing critical maneuvers "in the blind." Another concept described is the use of Earth-Moon L1 for lunar orbit rendezvous, rather than low lunar orbit as was done for Apollo. This rendezvous technique would avoid large plane change and high fuel cost associated with high latitude landing sites and long stay times. Earth-Moon L1 also offers unconstrained launch windows from the lunar surface. Farquhar claims this technique requires only slightly higher fuel cost than low lunar orbit rendezvous for short-stay equatorial landings. Farquhar also describes an Interplanetary Transportation System that would use libration points as terminals for an interplanetary shuttle. This approach would offer increased operational flexibility in terms of launch windows, rendezvous, aborts, etc. in comparison to elliptical orbit transfers. More recently, other works including Folta[3] and Howell[4] have shown that patching together unstable trajectories departing Earth-Moon libration points with stable trajectories approaching planetary libration points may also offer lower overall fuel costs than elliptical orbit transfers. Another concept Farquhar described was a Deep Space Relay at Earth-Moon IA and/or L5 that would serve as a high data rate optical navigation and communications relay satellite. The advantages in comparison to a geosynchronous relay are minimal Earth occultation, distance from large noise sources on Earth, easier pointing due to smaller relative velocity, and a large baseline for interferometry if both L4 and L5 are used.

Carpenter, J. Russell↗

Ocular input for human melatonin regulation: relevance to breast cancer

The impact of breast cancer on women across the world has been extensive and severe. As prevalence of breast cancer is greatest in industrialized regions, exposure to light at night has been proposed as a potential risk factor. This theory is supported by the epidemiological observations of decreased breast cancer in blind women and increased breast cancer in women who do shift-work. In addition, human, animal and in vitro studies which have investigated the melatonin-cancer dynamic indicate an apparent relationship between light, melatonin and cancer, albeit complex. Recent developments in understanding melatonin regulation by light in humans are examined, with particular attention to factors that contribute to the sensitivity of the light-induced melatonin suppression response. Specifically, the role of spectral characteristics of light is addressed, and recent relevant action spectrum studies in humans and other mammalian species are discussed. Across five action spectra for circadian and other non-visual responses, a peak sensitivity between 446-484 nm was identified. Under highly controlled exposure circumstances, less than 1 lux of monochromatic light elicited a significant suppression of nocturnal melatonin. In view of the possible link between light exposure, melatonin suppression and cancer risk, it is important to continue to identify the basic related ocular physiology. Visual performance, rather than circadian function, has been the primary focus of architectural lighting systems. It is now necessary to reevaluate lighting strategies, with consideration of circadian influences, in an effort to maximize physiological homeostasis and health.

Review↗

The effect of exercise and rest duration on the generation of venous gas bubbles at altitude

BACKGROUND: Decompression, as occurs with aviators and astronauts undergoing high altitude operations or with deep-sea divers returning to surface, can cause gas bubbles to form within the organism. Pressure changes to evoke bubble formation in vivo during depressurization are several orders of magnitude less than those required for gas phase formation in vitro in quiescent liquids. Preformed micronuclei acting as "seeds" have been proposed, dating back to the 1940's. These tissue gas micronuclei have been attributed to a minute gas phase located in hydrophobic cavities, surfactant-stabilized microbubbles, or arising from musculoskeletal activity. The lifetimes of these micronuclei have been presumed to be from a few minutes to several weeks. HYPOTHESIS: The greatest incidence of venous gas emboli (VGE) will be detected by precordial Doppler ultrasound with depressurization immediately following lower extremity exercise, with progressively reduced levels of VGE observed as the interval from exercise to depressurization lengthens. METHODS: In a blinded cross-over design, 20 individuals (15 men, 5 women) at sea level exercised by performing knee-bend squats (150 knee flexes over 10 min, 235-kcal x h(-1)) either at the beginning, middle, or end of a 2-h chair-rest period without an oxygen prebreathe. Seated subjects were then depressurized to 6.2 psia (6,706 m or 22,000 ft altitude equivalent) for 120 min with no exercise performed at altitude. RESULTS: Of the 20 subjects with VGE in the pulmonary artery, 10 demonstrated a greater incidence of bubbles with exercise performed just prior to depressurization, compared with decreasing bubble grades and incidence as the interval of rest increased prior to depressurization. No decompression illness was reported. CONCLUSIONS: There is a significant increase in decompression-induced bubble formation at 6.2 psia when lower extremity exercise is performed just prior to depressurization as compared with longer rest intervals. Analysis indicated that micronuclei half-life is on the order of an hour under these hypobaric conditions.

Controlled Clinical Trial↗

Integration of human sleep-wake regulation and circadian rhythmicity

The human sleep-wake cycle is generated by a circadian process, originating from the suprachiasmatic nuclei, in interaction with a separate oscillatory process: the sleep homeostat. The sleep-wake cycle is normally timed to occur at a specific phase relative to the external cycle of light-dark exposure. It is also timed at a specific phase relative to internal circadian rhythms, such as the pineal melatonin rhythm, the circadian sleep-wake propensity rhythm, and the rhythm of responsiveness of the circadian pacemaker to light. Variations in these internal and external phase relationships, such as those that occur in blindness, aging, morning and evening, and advanced and delayed sleep-phase syndrome, lead to sleep disruptions and complaints. Changes in ocular circadian photoreception, interindividual variation in the near-24-h intrinsic period of the circadian pacemaker, and sleep homeostasis can contribute to variations in external and internal phase. Recent findings on the physiological and molecular-genetic correlates of circadian sleep disorders suggest that the timing of the sleep-wake cycle and circadian rhythms is closely integrated but is, in part, regulated differentially.

Review↗

Analysis and visualization of single-trial event-related potentials

In this study, a linear decomposition technique, independent component analysis (ICA), is applied to single-trial multichannel EEG data from event-related potential (ERP) experiments. Spatial filters derived by ICA blindly separate the input data into a sum of temporally independent and spatially fixed components arising from distinct or overlapping brain or extra-brain sources. Both the data and their decomposition are displayed using a new visualization tool, the "ERP image," that can clearly characterize single-trial variations in the amplitudes and latencies of evoked responses, particularly when sorted by a relevant behavioral or physiological variable. These tools were used to analyze data from a visual selective attention experiment on 28 control subjects plus 22 neurological patients whose EEG records were heavily contaminated with blink and other eye-movement artifacts. Results show that ICA can separate artifactual, stimulus-locked, response-locked, and non-event-related background EEG activities into separate components, a taxonomy not obtained from conventional signal averaging approaches. This method allows: (1) removal of pervasive artifacts of all types from single-trial EEG records, (2) identification and segregation of stimulus- and response-locked EEG components, (3) examination of differences in single-trial responses, and (4) separation of temporally distinct but spatially overlapping EEG oscillatory activities with distinct relationships to task events. The proposed methods also allow the interaction between ERPs and the ongoing EEG to be investigated directly. We studied the between-subject component stability of ICA decomposition of single-trial EEG epochs by clustering components with similar scalp maps and activation power spectra. Components accounting for blinks, eye movements, temporal muscle activity, event-related potentials, and event-modulated alpha activities were largely replicated across subjects. Applying ICA and ERP image visualization to the analysis of sets of single trials from event-related EEG (or MEG) experiments can increase the information available from ERP (or ERF) data. Copyright 2001 Wiley-Liss, Inc.

Non-NASA Center↗

Comparison of efficacy of ginger with various antimotion sickness drugs

Ginger and several other medications were compared with scopolamine and d-amphetamine for effectiveness in prevention of motion sickness. Methods: Double-blind techniques were used. The subjects were given the medications two hours before they were rotated in a chair making head movements until a symptom total short of vomiting was reached. Standardized N.A.S.A. techniques were used for speed of rotation and end-point of motion sickness. Results: The three doses of ginger were all at the placebo level of efficacy. Amitriptyline, ethopropazine and trihexyphenidyl increased the tolerated head movements but the increase was not statistically significant. Significant levels of protection were produced by dimenhydrinate, promethazine, scopolamine and d-amphetamine. Protection was further increased by combination of these latter drugs with d-amphetamine. Efficacy was greatest as the dose was increased. Conclusions: The medication of choice in this study was scopolamine 0.6 mg with d-amphetamine 10 mg. This combination provided good protection with acceptable side effects.

Non-NASA Center↗

Radio frequency interference at Jodrell Bank Observatory within the protected 21 cm band

Radio frequency interference (RFI) will provide one of the most difficult challenges to systematic Searches for Extraterrestrial Intelligence (SETI) at microwave frequencies. The SETI-specific equipment is being optimized for the detection of signals generated by a technology rather than those generated by natural processes in the universe. If this equipment performs as expected, then it will inevitably detect many signals originating from terrestrial technology. If these terrestrial signals are too numerous and/or strong, the equipment will effectively be blinded to the (presumably) weaker extraterrestrial signals being sought. It is very difficult to assess how much of a problem RFI will actually represent to future observations, without employing the equipment and beginning the search. In 1983 a very high resolution spectrometer was placed at the Nuffield Radio Astronomy Laboratories at Jodrell Bank, England. This equipment permitted an investigation of the interference environment at Jodrell Bank, at that epoch, and at frequencies within the 21 cm band. This band was chosen because it has long been "protected" by international agreement; no transmitters should have been operating at those frequencies. The data collected at Jodrell Bank were expected to serve as a "best case" interference scenario and provide the minimum design requirements for SETI equipment that must function in the real and noisy environment. This paper describes the data collection and analysis along with some preliminary conclusions concerning the nature of the interference environment at Jodrell Bank.

NASA Discipline Number 52-60↗

Short-term hemodynamic performance of the mitral Carpentier-Edwards PERIMOUNT pericardial valve. Carpentier-Edwards PERIMOUNT Investigators

BACKGROUND: Although long-term durability data exist, little data are available concerning the hemodynamic performance of the Carpentier-Edwards PERIMOUNT pericardial valve in the mitral position. METHODS: Sixty-nine patients who were implanted with mitral PERIMOUNT valves at seven international centers between January 1996 and February 1997 consented to participate in a short-term echocardiography follow-up. Echocardiographs were collected at a mean of 600+/-133 days after implantation (range, 110 to 889 days); all underwent blinded core lab analysis. RESULTS: At follow-up, peak gradients were 9.09+/-3.43 mm Hg (mean, 4.36+/-1.79 mm Hg) and varied inversely with valve size (p < 0.05). The effective orifice areas were 2.5+/-0.6 cm2 and tended to increase with valve size (p = 0.08). Trace mitral regurgitation (MR) was common (n = 48), 9 patients had mild MR, 1 had moderate MR, none had severe MR. All MR was central (n = 55) or indeterminate (n = 3). No paravalvular leaks were observed. Mitral regurgitation flow areas were 3.4+/-2.8 cm2 and were without significant volumes. CONCLUSIONS: In this multicenter study, these mitral valves are associated with trace, although physiologically insignificant, central MR. Despite known echocardiographic limitations, the PERIMOUNT mitral valves exhibit similar hemodynamics to other prosthetic valves.

Clinical Trial↗

Comparison of MPEG-1 digital videotape with digitized sVHS videotape for quantitative echocardiographic measurements

Digital format is rapidly emerging as a preferred method for displaying and retrieving echocardiographic studies. The qualitative diagnostic accuracy of Moving Pictures Experts Group (MPEG-1) compressed digital echocardiographic studies has been previously reported. The goals of the present study were to compare quantitative measurements derived from MPEG-1 recordings with the super-VHS (sVHS) videotape clinical standard. Six reviewers performed blinded measurements from still-frame images selected from 20 echocardiographic studies that were simultaneously acquired in sVHS and MPEG-1 formats. Measurements were obtainable in 1401 (95%) of 1486 MPEG-1 variables compared with 1356 (91%) of 1486 sVHS variables (P <.001). Excellent agreement existed between MPEG-1 and sVHS 2-dimensional linear measurements (r = 0.97; MPEG-1 = 0.95[sVHS] + 1.1 mm; P <.001; Delta = 9% +/- 10%), 2-dimensional area measurements (r = 0.89), color jet areas (r = 0.87, p <.001), and Doppler velocities (r = 0.92, p <.001). Interobserver variability was similar for both sVHS and MPEG-1 readings. Our results indicate that quantitative off-line measurements from MPEG-1 digitized echocardiographic studies are feasible and comparable to those obtained from sVHS.

NASA Discipline Cardiopulmonary↗

Qualitative and quantitative effects of harmonic echocardiographic imaging on endocardial edge definition and side-lobe artifacts

Harmonic imaging is a new ultrasonographic technique that is designed to improve image quality by exploiting the spontaneous generation of higher frequencies as ultrasound propagates through tissue. We studied 51 difficult-to-image patients with blinded side-by-side cineloop evaluation of endocardial border definition by harmonic versus fundamental imaging. In addition, quantitative intensities from cavity versus wall were compared for harmonic versus fundamental imaging. Harmonic imaging improved left ventricular endocardial border delineation over fundamental imaging (superior: harmonic = 71.1%, fundamental = 18.7%; similar: 10.2%; P <.001). Quantitative analysis of 100 wall/cavity combinations demonstrated brighter wall segments and more strikingly darker cavities during harmonic imaging (cavity intensity on a 0 to 255 scale: fundamental = 15.6 +/- 8.6; harmonic = 6.0 +/- 5.3; P <.0001), which led to enhanced contrast between the wall and cavity (1.89 versus 1.19, P <.0001). Harmonic imaging reduces side-lobe artifacts, resulting in a darker cavity and brighter walls, thereby improving image contrast and endocardial delineation.

NASA Discipline Cardiopulmonary↗

Stress-induced reactivation of Epstein-Barr virus in astronauts

Herpesviruses are leading causes of infectious blindness and death in immunocompromised individuals. Impaired cellular immunity, which is known to result in increased frequency and severity of herpesvirus infections, has been demonstrated both during and after spaceflight. Therefore, we examined whether Epstein-Barr virus (EBV), a well-characterized latent herpesvirus, undergoes reactivation in astronauts. Sera from Shuttle astronauts, taken before and after spaceflight, were examined for evidence of EBV reactivation. The geometric mean antibody titer to EBV viral capsid antigen (VCA) was significantly increased prior to flight compared to baseline (p = 0. 0001). After spaceflight, evidence of acute lytic replication was found in which 8- to 64-fold increases in EBV early antigen (EA) antibodies occurred without significant increases in antibodies to measles virus. Additionally, stress-induced shifts in circulating leukocytes and elevated levels of urinary cortisol and epinephrine were found. Overall, significant increases in EA or high VCA/EA antibody titers were found in 8 of 23 (35%) male astronauts and 3 of 5 (60%) female astronauts. These results indicate that stress reactivates EBV prior to flight and suggest that acute lytic replication of EBV occurs during spaceflight. Copyright 2000 S. Karger AG, Basel.

NASA Discipline Environmental Health↗